Bioactivity screening unit

Facility/equipment: Equipment

  • Location

    Biocenter 2

    Helsinki

    Finland

Equipments Details

Description

The Bioactivity Screening Unit provides access to instrumentation and technologies amenable for a wide range of applications in drug discovery, chemical biology and related research fields. Our instrumentation cover automated liquid handling and various detection technologies, allowing flexible design and use of bioassays from biochemical to complex cell-based assays. We also offer guidance in assay selection, development and validation, HTS and follow-up assays. The unit is a member of the Drug Discovery and Chemical Biology (DDCB) network, a national infrastructure platform supported by Biocenter Finland.

Details

NameBioactivity screening unit
Acquisition date14/12/2015

Type of research infrastructure

  • Equipment

Fields of Science and Free Keywords

  • 317 Pharmacy
  • Drug discovery
  • high throughput screening
  • 1182 Biochemistry, cell and molecular biology

ESFRI thematic areas

  • Biological and Medical Sciences

UH research infrastructure classification

  • Research Laboratory

Research Output

Synthesis and Antiproliferative Activity of Marine Bromotyrosine Purpurealidin I and Its Derivatives

Bhat, C., Ilina, P., Tilli, I., Vorácova, M., Bruun, T., Barba, V., Hribernik, N., Lillsunde, K-E., Mäki-Lohiluoma, E., Rüffer, T., Lang, H., Yli-Kauhaluoma, J., Kiuru, P. & Tammela, P., 3 Dec 2018, In : Marine Drugs. 16, 12, 26 p., 481.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors

Tomašič, T., Mirt, M., Barančoková, M., Ilaš, J., Zidar, N., Tammela, P. S. M. & Kikelj, D., 1 Jan 2017, In : Bioorganic & Medicinal Chemistry. 25, 1, p. 338-349 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Discovery of bentzothiazole scaffold-based DNA gyrase B inhibitors

Gjorgjieva, M., Tomašič, T., Barančokova, M., Katsamakas, S., Ilaš, J., Tammela, P., Peterlin Mašič, L. & Kikelj, D., Oct 2016, In : Journal of Medicinal Chemistry. 59, 19, p. 8941-8954 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Projects

EU-OPENSCREEN

Virtanen, H., Wennerberg, K., Urtti, A. & Tammela, P.

01/11/2011 → …

Project: Other project

Activities

  • 3 Membership or other role in research network
  • 1 Other tasks of an expert in private sector

Thermo Fisher Scientific (External organisation)

Päivi Tammela (Expert)
1 Nov 2016

Activity: Membership typesOther tasks of an expert in private sector

Nordic Chemical Biology Consortium (External organisation)

Päivi Tammela (Member)
2014 → …

Activity: Membership typesMembership or other role in research network

Drug Discovery and Chemical Biology Network (DDCB) (External organisation)

Päivi Tammela (Member)
2011 → …

Activity: Membership typesMembership or other role in research network