Bioactivity screening unit

Facility/equipment: Core Facility

  • Location

    Biocenter 2

    Helsinki

    Finland

Research Output

2018

Synthesis and Antiproliferative Activity of Marine Bromotyrosine Purpurealidin I and Its Derivatives

Bhat, C., Ilina, P., Tilli, I., Vorácova, M., Bruun, T., Barba, V., Hribernik, N., Lillsunde, K-E., Mäki-Lohiluoma, E., Rüffer, T., Lang, H., Yli-Kauhaluoma, J., Kiuru, P. & Tammela, P., 3 Dec 2018, In : Marine Drugs. 16, 12, 26 p., 481.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
2017

Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors

Tomašič, T., Mirt, M., Barančoková, M., Ilaš, J., Zidar, N., Tammela, P. S. M. & Kikelj, D., 1 Jan 2017, In : Bioorganic & Medicinal Chemistry. 25, 1, p. 338-349 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
2016

Discovery of bentzothiazole scaffold-based DNA gyrase B inhibitors

Gjorgjieva, M., Tomašič, T., Barančokova, M., Katsamakas, S., Ilaš, J., Tammela, P., Peterlin Mašič, L. & Kikelj, D., Oct 2016, In : Journal of Medicinal Chemistry. 59, 19, p. 8941-8954 14 p.

Research output: Contribution to journalArticleScientificpeer-review

New N-phenyl-4,5-dibromopyrrolamides and N-phenylindolamides as ATPase inhibitors of DNA gyrase

Zidar, N., Tomasic, T., Macut, H., Sirc, A., Brvar, M., Montalvao, S., Tammela, P., Ilas, J. & Kikelj, D., 30 Mar 2016, In : European Journal of Medicinal Chemistry. 117, p. 197-211 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Synthesis and biological evaluation of crown ether acyl derivatives

Febles, M., Montalvao, S. I. G. H., Crespín, G. D., Norte, M., Padrón, J. M., Tammela, P. S. M., Fernández, J. J. & Daranas, A. H., Nov 2016, In : Bioorganic & Medicinal Chemistry Letters. 26, 22, p. 5591-5593 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
2015

Integrated in vitro - in silico screening strategy for the discovery of antibacterial compounds

Nybond, S., Ghemtio, L., Nawrot, D., Karp, M., Xhaard, H. & Tammela, P., 2015, In : Assay and drug development technologies. 13, 1, p. 25-33 9 p.

Research output: Contribution to journalArticleScientificpeer-review