Instruct-HiLIFE CryoEM core facility

Facility/equipment: Core Facility

  • Location

    Viikinkaari 9

    Viikki campus, Biocenter 1, staircase C, 1st floor

    00790

    Unknown

Description

CryoEM unit provides high-resolution imaging of nanoparticles, such as virus and protein complexes in the order of 200 KDa upwards (~10 to 300 nm in diameter). CryoEM is particularly useful for objects that are too large, unstable or variable to be studied by X-ray crystallography or NMR. It can be used to understand the structure, assembly and function of various biological macromolecule complexes. The cryoEM data can be used with image processing software to make 3D-models.Training in three-dimensional image reconstruction is given through fortnightly to monthly visits for data processing. Correlative light microscopy and cryoEM is a unique national service.
CryoEM core facility together with Biocomplex, NMR, and protein crystallization core facilities form Instruct-HiLIFE platform of Integrated Structural Cell Biology, which operates both at the Faculty of Biological and Environmental Sciences and Institute of Biotechnology (HiLIFE).

Type of research infrastructure

  • Service
  • Equipment

Fields of Science and Free Keywords

  • 1182 Biochemistry, cell and molecular biology
  • 1183 Plant biology, microbiology, virology
  • 119 Other natural sciences

ESFRI thematic areas

  • Biological and Medical Sciences

UH research infrastructure classification

  • Core Facility