• P.O. Box 65 (Viikinkaari 1), Biocentre 3

    00014 University of Helsinki

    Finland

Organization profile

Organisation Profile

Our ability to see in vastly varying conditions depends critically on the outstanding performance of vision. Vision begins in the neural circuits of the retina, which operates with a remarkable fidelity. We study novel signal processing mechanisms and their adaptive dynamics at the synaptic and cellular-element level across the entire neural circuit of the retina. We do so by combining a battery of techniques allowing precise manipulations of local signal and noise statistics in a well-defined retinal circuit relying on genetically modified mice, molecularly tailored artificial visual pigment molecules, and cutting- edge electrophysiological recording techniques. We seek to understand the functional implications of novel retinal signal processing mechanisms by correlating our results with the output of the entire visual system measured in mouse behavioral experiments and human psychophysics experiments.

For further information please see our website.

More group members

International and National Collaboration Publications and projects within past five years.

Publications

Mice Reach Higher Visual Sensitivity at Night by Using a More Efficient Behavioral Strategy

Koskela, S., Turunen, T. & Ala-Laurila, P., 6 Jan 2020, In : Current Biology. 30, 1, p. 42–53 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Paradoxical Rules of Spike Train Decoding Revealed at the Sensitivity Limit of Vision

Smeds, L., Takeshita, D., Turunen, T., Tiihonen, J. S., Westö, J., Martyniuk, N., Seppänen, A. J. & Ala-Laurila, P., 6 Nov 2019, In : Neuron. 104, 3, p. 576-+ 23 p.

Research output: Contribution to journalArticleScientificpeer-review

Rods progressively escape saturation to drive visual responses in daylight conditions

Tikidji-Hamburyan, A., Reinhard, K., Storchi, R., Dietter, J., Seitter, H., Davis, K. E., Idrees, S., Mutter, M., Walmsley, L., Bedford, R. A., Ueffing, M., Ala-Laurila, P., Brown, T. M., Lucas, R. J. & Muench, T. A., 27 Nov 2017, In : Nature Communications. 8, 17 p., 1813.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Activities

Invited talk: Cosyne workshop "Retinal circuits for seeing nature"

Petri Ala-Laurila (Speaker)
4 Mar 2019

Activity: Talk or presentation typesInvited talk

Mice reach higher visual sensitivity at night due to diurnal modulation of their behavioral strategy

Sanna Koskela (Invited speaker)
11 Sep 2019

Activity: Talk or presentation typesOral presentation

'Circadian Retina' satellite meeting

Sanna Koskela (Attendee)
9 Sep 201911 Sep 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

European Retina Meeting 2019

Lina Smeds (Poster Presentation)
12 Sep 201914 Sep 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

European Neuroscience Conference by Doctoral Students 2019

Lina Smeds (Poster Presentation)
24 Jun 201925 Jun 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Prizes

Marine Biological Laboratory Scholarship Award

Sanna Koskela (Recipient), 1 Mar 2018

Prize: Prizes and awards

Press / Media