Research Output per year
Organization profile
Organisation Profile
Our ability to see in vastly varying conditions depends critically on the outstanding performance of vision. Vision begins in the neural circuits of the retina, which operates with a remarkable fidelity. We study novel signal processing mechanisms and their adaptive dynamics at the synaptic and cellular-element level across the entire neural circuit of the retina. We do so by combining a battery of techniques allowing precise manipulations of local signal and noise statistics in a well-defined retinal circuit relying on genetically modified mice, molecularly tailored artificial visual pigment molecules, and cutting- edge electrophysiological recording techniques. We seek to understand the functional implications of novel retinal signal processing mechanisms by correlating our results with the output of the entire visual system measured in mouse behavioral experiments and human psychophysics experiments.
For further information please see our website.
International and National Collaboration
Publications and projects within past five years.
Publications
Mice Reach Higher Visual Sensitivity at Night by Using a More Efficient Behavioral Strategy
Koskela, S., Turunen, T. & Ala-Laurila, P., 6 Jan 2020, In : Current Biology. 30, 1, p. 42–53 16 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Mice have better performance at night in a photon detection task
Koskela, S., Turunen, T. & Ala-Laurila, P., 2019.Research output: Conference materials › Poster
Paradoxical Rules of Spike Train Decoding Revealed at the Sensitivity Limit of Vision
Smeds, L., Takeshita, D., Turunen, T., Tiihonen, J. S., Westö, J., Martyniuk, N., Seppänen, A. J. & Ala-Laurila, P., 6 Nov 2019, In : Neuron. 104, 3, p. 576-+ 23 p.Research output: Contribution to journal › Article › Scientific › peer-review
Rods progressively escape saturation to drive visual responses in daylight conditions
Tikidji-Hamburyan, A., Reinhard, K., Storchi, R., Dietter, J., Seitter, H., Davis, K. E., Idrees, S., Mutter, M., Walmsley, L., Bedford, R. A., Ueffing, M., Ala-Laurila, P., Brown, T. M., Lucas, R. J. & Muench, T. A., 27 Nov 2017, In : Nature Communications. 8, 17 p., 1813.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
The absolute limits of increment and decrement detection at low light levels
Koskela, S., Kilpeläinen, M., Laihi, A., Takeshita, D. & Ala-Laurila, P., 2017.Research output: Conference materials › Poster
Activities
Invited talk: Cosyne workshop "Retinal circuits for seeing nature"
Petri Ala-Laurila (Speaker)4 Mar 2019
Activity: Talk or presentation types › Invited talk
Mice reach higher visual sensitivity at night due to diurnal modulation of their behavioral strategy
Sanna Koskela (Invited speaker)11 Sep 2019
Activity: Talk or presentation types › Oral presentation
'Circadian Retina' satellite meeting
Sanna Koskela (Attendee)9 Sep 2019 → 11 Sep 2019
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
European Retina Meeting 2019
Lina Smeds (Poster Presentation)12 Sep 2019 → 14 Sep 2019
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
European Neuroscience Conference by Doctoral Students 2019
Lina Smeds (Poster Presentation)24 Jun 2019 → 25 Jun 2019
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Prizes
Marine Biological Laboratory Scholarship Award
Sanna Koskela (Recipient), 1 Mar 2018
Prize: Prizes and awards
Press / Media
Interview: Helsingin Sanomat - its Teema magazine
01/01/2016
1 Media contribution
Press/Media: Press / Media
Interview: Academy of Finland website: Tutkijoiden ja rahoitustahojen hyvä kommunikaatio edistää tiedettä
12/11/2015
1 Media contribution
Press/Media: Press / Media