Projects per year
Organization profile
Our ability to see in vastly varying conditions depends critically on the outstanding performance of vision. Vision begins in the neural circuits of the retina, which operates with a remarkable fidelity. We study novel signal processing mechanisms and their adaptive dynamics at the synaptic and cellular-element level across the entire neural circuit of the retina. We do so by combining a battery of techniques allowing precise manipulations of local signal and noise statistics in a well-defined retinal circuit relying on genetically modified mice, molecularly tailored artificial visual pigment molecules, and cutting- edge electrophysiological recording techniques. We seek to understand the functional implications of novel retinal signal processing mechanisms by correlating our results with the output of the entire visual system measured in mouse behavioral experiments and human psychophysics experiments.
For further information please see our website.
Fields of Science
- 3112 Neurosciences
- 1184 Genetics, developmental biology, physiology
International and National Collaboration
Profiles
Projects
- 1 Active
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Retinal OFF ganglion cells allow detection of quantal shadows at starlight
Westö, J., Martyniuk, N., Koskela, S., Turunen, T., Pentikäinen, S. & Ala-Laurila, P., 11 Jul 2022, In: Current Biology. 32, 13, p. 2848-2857 17 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Mice Reach Higher Visual Sensitivity at Night by Using a More Efficient Behavioral Strategy
Koskela, S., Turunen, T. & Ala-Laurila, P., 6 Jan 2020, In: Current Biology. 30, 1, p. 42–53 16 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
The limits of visual sensitivity and its circadian control
Koskela, S., 9 Oct 2020, Helsingin yliopisto.Research output: Thesis › Doctoral Thesis › Collection of Articles
Open Access -
Mice have better performance at night in a photon detection task
Koskela, S., Turunen, T. & Ala-Laurila, P., 2019.Research output: Conference materials › Poster
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Paradoxical Rules of Spike Train Decoding Revealed at the Sensitivity Limit of Vision
Smeds, L., Takeshita, D., Turunen, T., Tiihonen, J. S., Westö, J., Martyniuk, N., Seppänen, A. J. & Ala-Laurila, P., 6 Nov 2019, In: Neuron. 104, 3, p. 576-+ 23 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Activities
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'Circadian Retina' satellite meeting
Sanna Koskela (Attendee)
9 Sep 2019 → 11 Sep 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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European Retina Meeting 2019
Lina Smeds (Poster Presentation)
12 Sep 2019 → 14 Sep 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Mice reach higher visual sensitivity at night due to diurnal modulation of their behavioral strategy
Sanna Koskela (Invited speaker)
11 Sep 2019Activity: Talk or presentation types › Oral presentation
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Invited talk: Cosyne workshop "Retinal circuits for seeing nature"
Petri Ala-Laurila (Speaker)
4 Mar 2019Activity: Talk or presentation types › Invited talk
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Helsinki Network Brain & Mind (External organisation)
Sanna Koskela (Board member)
1 May 2019 → …Activity: Membership types › Membership or other role in national/international committee, council, board
Prizes
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Marine Biological Laboratory Scholarship Award
Koskela, Sanna (Recipient), 1 Mar 2018
Prize: Prizes and awards
Press/Media
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Sammakko näkee paremmin paetessaan kuin paritellessaan – Eläimen näkökyky riippuu siitä, mihin näköä kulloinkin tarvitaan
Sanna Koskela, Petri Ala-Laurila, Kristian Donner & Tuomas Turunen
29/10/2020
1 item of Media coverage
Press/Media: Press / Media
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Finding your way in the dark - Depends on your internal clock
05/01/2020
1 item of Media coverage
Press/Media: Press / Media
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Circadian rhythm affects everything, even the day we see
22/12/2019
1 item of Media coverage
Press/Media: Press / Media
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Finding Your Way in the Dark Depends on Your Internal Clock: Study
21/12/2019
1 item of Media coverage
Press/Media: Press / Media
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Finding your way in the dark depends on your internal clock
19/12/2019 → 20/12/2019
5 items of Media coverage
Press/Media: Press / Media