• Finland

Publications

2020

2019 ESC Guidelines for the dignosis and management of acute pulmonary embolism development Toed in colaboration with the European Respiratory Society (ERS)

Konstantinides, S., Meyer, G., Becattini, C., Bueno, H., Geersing, G-J., Harjola, V-P., Huisman, M., Humbert, M., Jennings, C. S., Jimenez, D., Kucher, N., Lang, I. M., Lankeit, M., Lorusso, R., Mazzolai, L., Meneveau, N., Ainle, F. N., Prandoni, P., Pruszczyk, P., Righini, M. & 3 others, Torbicki, A., Van Belle, E. & Luis Zamorano, J., 21 Jan 2020, In : European Heart Journal. 41, 4, p. 543-603 61 p.

Research output: Contribution to journalArticleScientificpeer-review

Antagonism of peripheral opioid receptors by methylnaltrexone does not prevent morphine tolerance in rats

Blomqvist, K. J., Dudek, K., Viisanen, H., Mätlik, K., Ahlström, F. H. G., Laitila, J., Kalso, E. A., Rauhala, P. V. & Lilius, T. O., 27 May 2020, In : Journal of Neuroscience Research. 2020, 00, 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Antimicrobial Stewardship in Hematological Patients at the intensive care unit: a global cross-sectional survey from the Nine-i Investigators Network

Nine-I Study Grp, Rello, J., Sarda, C., Azoulay, E. & Valkonen, M., Feb 2020, In : European Journal of Clinical Microbiology & Infectious Diseases. 39, 2, p. 385-392 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

A physiologically based pharmacokinetic model of voriconazole integrating time-dependent inhibition of CYP3A4, genetic polymorphisms of CYP2C19 and predictions of drug-drug interactions

Li, X., Frechen, S., Moj, D., Lehr, T., Taubert, M., Hsin, S., Mikus, G., Neuvonen, P. J., Olkkola, K., Saari, T. & Fuhr, U., Jun 2020, In : Clinical Pharmacokinetics. 59, 6, p. 781-808 28 p.

Research output: Contribution to journalArticleScientificpeer-review

Clinical examination findings as predictors of acute kidney injury in critically ill patients

SICS Study Grp, Wiersema, R. E., Koeze, J., Eck, R. J., Vaara, S. T. & Van der Horst, I. C. C., Jan 2020, In : Acta Anaesthesiologica Scandinavica. 64, 1, p. 69–74 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Cold fluids for induction of targeted temperature management: A sub-study of the TTH48 trial

Holm, A., Kirkegaard, H., Taccone, F., Soreide, E., Grejs, A., Duez, C., Jeppesen, A., Toome, V., Hassager, C. C., Rasmussen, B. S., Laitio, T., Storm, C., Hästbacka, J. & Skrifvars, M. B., 1 Mar 2020, In : Resuscitation. 148, p. 90-97 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Costs and Cost-Utility of Critical Care and Subsequent Health Care: A Multicenter Prospective Study*

Jukarainen, S., Mildh, H., Pettilä, V., Häkkinen, U., Peltola, M., Ala-Kokko, T., Reinikainen, M. & Vaara, S. T., May 2020, In : Critical Care Medicine. 48, 5, p. E345-E355 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Data-science-based subgroup analysis of persistent pain during 3 years after breast cancer surgery A prospective cohort study

Loetsch, J., Ultsch, A. & Kalso, E., Mar 2020, In : European Journal of Anaesthesiology. 37, 3, p. 235-246 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Different applications of the KDIGO criteria for AKI lead to different incidences in critically ill patients: a post hoc analysis from the prospective observational SICS-II study

Wiersema, R., Jukarainen, S., Eck, R. J., Kaufmann, T., Koeze, J., Keus, F., Pettilä, V., van der Horst, I. C. C. & Vaara, S. T., 21 Apr 2020, In : Critical Care. 24, 1, 8 p., 164.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Digitaalisia työkaluja kivun hoitoon

Hamunen, K., 2020, In : Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti. 23, 1, p. 7-10 4 p.

Research output: Contribution to journalArticleProfessional

Douleur Neuropathique 4 (DN4) stratifies possible and definite neuropathic pain after surgical peripheral nerve lesion

Aho, T., Mustonen, L., Kalso, E. & Harno, H., Feb 2020, In : European Journal of Pain. 24, 2, p. 413-422 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Doxapram as an additive to propofol sedation for endoscopic retrograde cholangiopancreatography: a placebo-controlled, randomized, double-blinded study

Jokelainen, J., Belozerskikh, A., Mustonen, H., Udd, M., Kylänpää, L., Lindström, O., Mazanikov, M. & Pöyhiä, R., 28 Jan 2020, In : Surgical Endoscopy. 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Early Osmotherapy in Severe Traumatic Brain Injury: An International Multicenter Study

TBI Collaborative, Anstey, J. R., Taccone, F. S., Udy, A. A. & Skrifvars, M. B., Jan 2020, In : Journal of Neurotrauma. 37, 1, p. 178-184 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect and safety of 4% albumin in the treatment of cardiac surgery patients: study protocol for the randomized, double-blind, clinical ALBICS (ALBumin In Cardiac Surgery) trial

Vlasov, H., Juvonen, T., Hiippala, S., Suojaranta, R., Peltonen, M., Schramko, A., Arvonen, K., Salminen, U-S., Kleine Budde, I., Eränen, T., Mazanikov, M., Meinberg, M., Vähäsilta, T., Wilkman, E., Pettilä, V. & Pesonen, E., 28 Feb 2020, In : Trials. 21, 1, 10 p., 235.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Effect of Intravenous Interferon beta-1a on Death and Days Free From Mechanical Ventilation Among Patients With Moderate to Severe Acute Respiratory Distress Syndrome A Randomized Clinical Trial

INTEREST Study Grp, Ranieri, V. M., Pettilä, V., Karvonen, M. K., Jalkanen, J., Nightingale, P., Okkonen, M. & Bellingan, G., 25 Feb 2020, In : JAMA : The Journal of the American Medical Association. 323, 8, p. 725-733 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Electrochemical Detection of Oxycodone and Its Main Metabolites with Nafion-Coated Single-Walled Carbon Nanotube Electrodes

Mynttinen, E., Wester, N., Lilius, T., Kalso, E., Mikladal, B., Varjos, I., Sainio, S., Jiang, H., Kauppinen, E. I., Koskinen, J. & Laurila, T., 16 Jun 2020, In : Analytical Chemistry. 92, 12, p. 8218-8227 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Enhanced recovery protocol in laparoscopic liver surgery

Savikko, J., Vikatmaa, L., Hiltunen, A-M., Mallat, N., Tukiainen, E., Salonen, S-M. & Nordin, A., 27 Feb 2020, In : Surgical Endoscopy. 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

External validation and comparison of the CardShock and IABP-SHOCK II risk scores in real-world cardiogenic shock patients

Rivas-Lasarte, M., Sans-Rosello, J., Collado-Lledo, E., Garcia-Fernandez, V., Noriega, F. J., Hernandez-Perez, F. J., Fernandez-Martinez, J., Ariza, A., Lidon, R-M., Viana-Tejedor, A., Segovia-Cubero, J., Harjola, V-P., Lassus, J., Thiele, H. & Sionis, A., 31 Jan 2020, In : European Heart Journal: Acute Cardiovascular Care. 9 p., 2048872619895230.

Research output: Contribution to journalArticleScientificpeer-review

Gender differences in mortality and quality of life after septic shock: A post-hoc analysis of the ARISE study

ARISE Investigators, Luethi, N., Bailey, M., Harjola, V-P., Okkonen, M., Pettilä, V., Sutinen, E. & Wilkman, E., Feb 2020, In : Journal of Critical Care. 55, p. 177-183 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Haemodynamics and vasopressor support during prolonged targeted temperature management for 48 hours after out-of-hospital cardiac arrest: a post hoc substudy of a randomised clinical trial

Grand, J., Hassager, C., Skrifvars, M. B., Tiainen, M., Grejs, A. M., Jeppesen, A. N., Duez, C. H. V., Rasmussen, B. S., Laitio, T., Nee, J., Taccone, F., Soreide, E. & Kirkegaard, H., 17 Jun 2020, In : European Heart Journal: Acute Cardiovascular Care. 12 p., 2048872620934305.

Research output: Contribution to journalArticleScientificpeer-review

Hospital-at-home network in Finland

Ohvanainen, A., Niemi-Murola, L., Elonheimo, O. & Pöyhiä, R., 14 Feb 2020, In : International Journal of Healthcare Management. 7 p.

Research output: Contribution to journalArticleScientificpeer-review

How near is near infrared spectroscopy in pre-hospital care?

Skrifvars, M. B. & Aneman, A., Jan 2020, In : Acta Anaesthesiologica Scandinavica. 64, 1, p. 2-3 2 p.

Research output: Contribution to journalEditorialScientific

Imaging in patients with suspected acute heart failure: timeline approach position statement on behalf of the Heart Failure Association of the European Society of Cardiology

Celutkiene, J., Lainscak, M., Anderson, L., Gayat, E., Grapsa, J., Harjola, V-P., Manka, R., Nihoyannopoulos, P., Filardi, P. P., Vrettou, R., Anker, S. D., Filippatos, G., Mebazaa, A., Metra, M., Piepoli, M., Ruschitzka, F., Zamorano, J. L., Rosano, G. & Seferovic, P., Feb 2020, In : European Journal of Heart Failure. 22, 2, p. 181-195 15 p.

Research output: Contribution to journalArticleScientificpeer-review

In-hospital cardiac arrest in hospitals with mature rapid response systems - a multicentre, retrospective cohort study

Tirkkonen, J., Skrifvars, M. B., Parr, M., Tamminen, T. & Aneman, A., Apr 2020, In : Resuscitation. 149, p. 109-116 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Kipuklinikan psykologit tarjoavat tukea työkavereille

Sipilä, R., 2020, In : Finnanest.. 53, 3, p. 250-252 3 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Long-term patient-important outcomes after septic shock: A protocol for 1-year follow-up of the CLASSIC trial

Kjaer, M-B. N., Meyhoff, T. S., Madsen, M. B., Hjortrup, P. B., Moller, M. H., Egerod, I., Wetterslev, J., Lange, T., Cronhjort, M., Laake, J. H., Jakob, S. M., Nalos, M., Pettilä, V., van der Horst, I. C. C., Ostermann, M., Mouncey, P., Cecconi, M., Ferrer, R., Malbrain, M. L. N. G., Ahlstedt, C. & 10 others, Hoffmann, S., Bestle, M. H., Gyldensted, L., Nebrich, L., Russell, L., Vang, M., Solling, C., Brochner, A. C., Rasmussen, B. S. & Perner, A., Mar 2020, In : Acta Anaesthesiologica Scandinavica. 64, 3, p. 410-416 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Long-term quality of life after surgery of head and neck cancer with microvascular reconstruction: a prospective study with 4.9-years follow-up

Kainulainen, S., Koivusalo, A. M., Roine, R. P., Wilkman, T., Sintonen, H., Törnwall, J., Thoren, H. & Lassus, P., Mar 2020, In : Oral and Maxillofacial Surgery. 24, 1, p. 11-17 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Machine-learned identification of psychological subgroups with relation to pain interference in patients after breast cancer treatments

Sipilä, R., Kalso, E. & Lötsch, J., Apr 2020, In : Breast. 50, p. 71-80 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Open Access

Mortality prediction models in the adult critically ill: A scoping review

HEALICS Consortium, Keuning, B. E., Kaufmann, T., Wiersema, R., Pettilä, V. & van der Horst, I. C. C., Apr 2020, In : Acta Anaesthesiologica Scandinavica. 64, 4, p. 424-442 19 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Near-Infrared Spectroscopy in Adult Circulatory Shock: A Systematic Review

Varis, E., Pettilä, V. & Wilkman, E., 20 Feb 2020, In : Journal of Intensive Care Medicine. 20 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Noninterventional follow-up vs fluid bolus in RESPONSE to oliguria-The RESPONSE trial protocol and statistical analysis plan

Inkinen, N., Selander, T., Pettila, V., Valkonen, M., Bäcklund, M., Wennervirta, J., Pulkkinen, A., Hästbacka, J. & Vaara, S. T., 28 Apr 2020, In : Acta Anaesthesiologica Scandinavica. 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Nonspecific complaints in the emergency department - a systematic review

Kemp, K., Mertanen, R., Lääperi, M., Niemi-Murola, L., Lehtonen, L. & Castren, M., 28 Jan 2020, In : Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 28, 1, 12 p., 6.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Nuss ja Horner

Peil, P., 2020, In : Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti. 23, 1, p. 39-40 2 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Out-of-hospital Cardiac Arrest across the World: First Report from the International Liaison Committee on Resuscitation (ILCOR)

Kiguchi, T., Okubo, M., Nishiyama, C., Maconochie, I., Ong, M. E. H., Kern, K. B., Wyckoff, M. H., McNally, B., Christensen, E., Tjelmeland, I., Herlitz, J., Perkins, G. D., Booth, S., Finn, J., Shahidah, N., Shin, S. D., Bobrow, B. J., Morrison, L. J., Salo, A., Baldi, E. & 6 others, Burkart, R., Lin, C-H., Jouven, X., Soar, J., Nolan, J. P. & Iwami, T., Jul 2020, In : Resuscitation. 152, p. 39-49 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Pain and postoperative hemorrhage after tonsillectomy

Tolska, K., 2020, In : Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti. 23, 1, p. 58-59 2 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Päiväkirurgisen nielurisaleikkauksen jälkeinen kipu ja verenvuoto.

Tolska, K., 2020, In : Finnanest.. 53, 1, p. 67-69 3 p.

Research output: Contribution to journalArticleProfessional

Open Access

Perimän vaikutus akuutin munuaisvaurion synnyssä

Vilander, L. M., 2020, In : Finnanest.. 53, 3, p. 231-233 3 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Point-of-care creatinine measurements to predict acute kidney injury

Vaara, S. T., Glassford, N., Eastwood, G. M., Canet, E., Mårtensson, J. & Bellomo, R., Jun 2020, In : Acta Anaesthesiologica Scandinavica. 64, 6, p. 766-773 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Posttraumatic epilepsy in intensive care unit–treated pediatric traumatic brain injury patients

Mikkonen, E. D., Skrifvars, M. B., Reinikainen, M., Bendel, S., Laitio, R., Hoppu, S., Ala-Kokko, T., Karppinen, A. & Raj, R., 28 Mar 2020, In : Epilepsia. 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Prevalence of risk-drinking in critically ill patients, screened with carbohydrate-deficient transferrin and AUDIT-C score: A retrospective study

Uljas, E., Jalkanen, V., Kuitunen, A., Hynninen, M. & Hästbacka, J., Feb 2020, In : Acta Anaesthesiologica Scandinavica. 64, 2, p. 216-223 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Protocol and statistical analysis plan for the REstricted fluid therapy VERsus Standard trEatment in Acute Kidney Injury – REVERSE-AKI randomized controlled pilot trial

Vaara, S. T., Ostermann, M., Selander, T., Bitker, L., Schneider, A., Poli, E., Hoste, E., Joannidis, M., Zarbock, A., van Haren, F., Prowle, J., Pettilä, V. & Bellomo, R., Jul 2020, In : Acta Anaesthesiologica Scandinavica. 64, 6, p. 831-838 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Role of oxytocin in prevention of postpartum hemorrhage in unplanned out-of-hospital deliveries treated by emergency medical services

Klemettilä, E., Rahkonen, L., Nuutila, M., Laaperi, M. & Harve-Rytsälä, H., 28 Jan 2020, In : Acta Obstetricia et Gynecologica Scandinavica. 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Sensory profiles in women with neuropathic pain after breast cancer surgery

Mustonen, L., Vollert, J., Rice, A. S. C., Kalso, E. & Harno, H., Jul 2020, In : Breast Cancer Research and Treatment. 182, 2, p. 305-315 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Single-Walled Carbon Nanotube Network Electrodes for the Detection of Fentanyl Citrate

Wester, N., Mynttinen, E., Etula, J., Lilius, T., Kalso, E., Mikladal, B. F., Zhang, Q., Jiang, H., Sainio, S., Nordlund, D., Kauppinen, E., Laurila, T. & Koskinen, J., Feb 2020, In : Acs applied nano materials. 3, 2, p. 1203-1212 19 p.

Research output: Contribution to journalArticleScientificpeer-review

Survival after out-of-hospital cardiac arrest in Europe - Results of the EuReCa TWO study

Gräsner, J-T., Wnent, J., Herlitz, J., Perkins, G. D., Lefering, R., Tjelmeland, I., Koster, R. W., Masterson, S., Rossell-Ortiz, F., Maurer, H., Boettiger, B. W., Moertl, M., Mols, P., Alihodic, H., Hadibegovic, I., Ioannides, M., Truhlar, A., Wissenberg, M., Salo, A., Escutnaire, J. & 17 others, Nikolaou, N., Nagy, E., Jonsson, B. S., Wright, P., Semeraro, F., Clarens, C., Beesems, S., Cebula, G., Correia, V. H., Cimpoesu, D., Raffay, V., Trenkler, S., Markota, A., Stroemsoee, A., Burkart, R., Booth, S. & Bossaert, L., 1 Mar 2020, In : Resuscitation. 148, p. 218-226 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Symptom severity in burning mouth syndrome associates with psychological factors

Forssell, H., Teerijoki-Oksa, T., Puukka, P. & Estlander, A-M., Jun 2020, In : Journal of Oral Rehabilitation. 47, 6, p. 713-719 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Telephone triage performed by nurses reduces non-urgent ambulance missions: A prospective observational pilot study in Finland

Roivainen, P., Hoikka, M. J., Raatiniemi, L., Silfvast, T., Ala-Kokko, T. & Kääriäinen, M., Apr 2020, In : Acta Anaesthesiologica Scandinavica. 64, 4, p. 556-563 8 p.

Research output: Contribution to journalArticleScientificpeer-review

The circadian clock at the intercept of sleep and pain

Palada, V., Gilron, I., Canlon, B., Svensson, C. & Kalso, E., May 2020, In : Pain. 161, 5, p. 894-900 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review