Publications 2001 2020

2015

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Gaulton, K. J., Ferreira, T., Lee, Y., Raimondo, A., Maegi, R., Reschen, M. E., Mahajan, A., Locke, A., Rayner, N. W., Robertson, N., Scott, R. A., Prokopenko, I., Scott, L. J., Green, T., Sparso, T., Thuillier, D., Yengo, L., Grallert, H., Wahl, S., Franberg, M. & 199 othersStrawbridge, R. J., Kestler, H., Chheda, H., Eisele, L., Gustafsson, S., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Karssen, L. C., van Leeuwen, E. M., Willems, S. M., Li, M., Chen, H., Fuchsberger, C., Kwan, P., Ma, C., Linderman, M., Lu, Y., Thomsen, S. K., Rundle, J. K., Beer, N. L., van de Bunt, M., Chalisey, A., Kang, H. M., Voight, B. F., Abecasis, G. R., Almgren, P., Baldassarre, D., Balkau, B., Benediktsson, R., Blueher, M., Boeing, H., Bonnycastle, L. L., Bottinger, E. P., Burtt, N. P., Carey, J., Charpentier, G., Chines, P. S., Cornelis, M. C., Couper, D. J., Crenshaw, A. T., van Dam, R. M., Doney, A. S. F., Dorkhan, M., Edkins, S., Eriksson, J. G., Esko, T., Eury, E., Fadista, J., Flannick, J., Fontanillas, P., Fox, C., Franks, P. W., Gertow, K., Gieger, C., Gigante, B., Gottesman, O., Grant, G. B., Grarup, N., Groves, C. J., Hassinen, M., Have, C. T., Herder, C., Holmen, O. L., Hreidarsson, A. B., Humphries, S. E., Hunter, D. J., Jackson, A. U., Jonsson, A., Jorgensen, M. E., Jorgensen, T., Kao, W-H. L., Kerrison, N. D., Kinnunen, L., Klopp, N., Kong, A., Kovacs, P., Kraft, P., Kravic, J., Langford, C., Leander, K., Liang, L., Lichtner, P., Lindgren, C. M., Lindholm, E., Linneberg, A., Liu, C-T., Lobbens, S., Luan, J., Lyssenko, V., Mannisto, S., McLeod, O., Meyer, J., Mihailov, E., Mirza, G., Muehleisen, T. W., Mueller-Nurasyid, M., Navarro, C., Noethen, M. M., Oskolkov, N. N., Owen, K. R., Palli, D., Pechlivanis, S., Peltonen, L., Perry, J. R. B., Platou, C. G. P., Roden, M., Ruderfer, D., Rybin, D., van der Schouw, Y. T., Sennblad, B., Sigurdsson, G., Stancakova, A., Steinbach, G., Storm, P., Strauch, K., Stringham, H. M., Sun, Q., Thorand, B., Tikkanen, E., Tonjes, A., Trakalo, J., Tremoli, E., Tuomi, T., Wennauer, R., Wiltshire, S., Wood, A. R., Zeggini, E., Dunham, I., Birney, E., Pasquali, L., Ferrer, J., Loos, R. J. F., Dupuis, J., Florez, J. C., Boerwinkle, E., Pankow, J. S., van Duijn, C., Sijbrands, E., Meigs, J. B., Hu, F. B., Thorsteinsdottir, U., Stefansson, K., Lakka, T. A., Rauramaa, R., Stumvoll, M., Pedersen, N. L., Lind, L., Keinanen-Kiukaanniemi, S. M., Korpi-Hyovalti, E., Saaristo, T. E., Saltevo, J., Kuusisto, J., Laakso, M., Metspalu, A., Erbel, R., Joecke, K-H., Moebus, S., Ripatti, S., Salomaa, V., Ingelsson, E., Boehm, B. O., Bergman, R. N., Collins, F. S., Mohlke, K. L., Koistinen, H., Tuomilehto, J., Hveem, K., Njolstad, I., Deloukas, P., Donnelly, P. J., Frayling, T. M., Hattersley, A. T., de Faire, U., Hamsten, A., Illig, T., Peters, A., Cauchi, S., Sladek, R., Froguel, P., Hansen, T., Pedersen, O., Morris, A. D., Palmer, C. N. A., Kathiresan, S., Melander, O., Nilsson, P. M., Groop, L. C., Barroso, I., Langenberg, C., Wareham, N. J., O'Callaghan, C. A., Gloyn, A. L., Altshuler, D., Boehnke, M., Teslovich, T. M., McCarthy, M. I., Morris, A. P. & DIAbet Genetics Replication Meta-A, Dec 2015, In : Nature Genetics. 47, 12, p. 1415-1425 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic import and phenotype specific alleles associated with hyper-invasion in Campylobacter jejuni

Baig, A., McNally, A., Dunn, S., Paszkiewicz, K. H., Corander, J. & Manning, G., 24 Oct 2015, In : BMC Genomics. 16, 12 p., 852.

Research output: Contribution to journalArticleScientificpeer-review

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Genetic Loci Associated with Allergic Sensitization in Lithuanians

Sauliene, I., Greiciuviene, J., Sukiene, L., Juskeviciute, N., Benner, C., Zinkeviciene, A., Ripatti, S., Donner, K. & Kainov, D., 27 Jul 2015, In : PLoS One. 10, 7, 7 p., 0134188.

Research output: Contribution to journalArticleScientificpeer-review

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Genetic studies of body mass index yield new insights for obesity biology

Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., Powell, C., Vedantam, S., Buchkovich, M. L., Yang, J., Croteau-Chonka, D. C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z., Luan, J., Maegi, R., Randall, J. C., Winkler, T. W. & 44 othersWood, A. R., Workalemahu, T., Faul, J. D., Smith, J. A., Zhao, J. H., Zhao, W., Chen, J., Fehrmann, R., Hedman, A. K., Karjalainen, J., Schmidt, E. M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bolton, J. L., Bragg-Gresham, L., Eklund, N., Koskenvuo, M., Sandholm, N., Eriksson, J. G., Jousilahti, P., Kaprio, J., Sinisalo, J., Groop, L. C., Kivimaki, M., Perola, M., Tuomilehto, J., LifeLines Cohort Study, ADIPOGen Consortium, AGEN-BMI Working Grp, CARDIOGRAMplusC4D Consortium, CKDGen Consortium, GLGC, ICBP, MAGIC Investigators, MuTHER Consortium, MIGen Consortium, PAGE Consortium, ReproGen Consortium, GENIE Consortium, Int Endogene Consortium, Lokki, M-L. & Ripatti, S. O., 12 Feb 2015, In : Nature. 518, 7538, p. 197-U401 23 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population

Salo, P. P., Vaara, S., Kettunen, J., Pirinen, M., Sarin, A-P., Huikuri, H., Karhunen, P. J., Eskola, M., Nikus, K., Lokki, M-L., Ripatti, S., Havulinna, A. S., Salomaa, V., Palotie, A., Nieminen, M. S., Sinisalo, J. & Perola, M., 28 Oct 2015, In : PLoS One. 10, 10, 16 p., 0140576.

Research output: Contribution to journalArticleScientificpeer-review

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Genome-Wide Analysis of Evolutionary Markers of Human Influenza A(H1N1)pdm09 and A(H3N2) Viruses May Guide Selection of Vaccine Strain Candidates

Belanov, S. S., Bychkov, D., Benner, C., Ripatti, S., Ojala, T., Kankainen, M., Lee, H. K., Tang, J. W-T. & Kainov, D. E., Dec 2015, In : Genome Biology and Evolution. 7, 12, p. 3472-3483 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Genome-wide modeling of transcription kinetics reveals patterns of RNA production delays

Honkela, A., Peltonen, J., Topa, H., Charapitsa, I., Matarese, F., Grote, K., Stunnenberg, H. G., Reid, G., Lawrence, N. D. & Rattray, M., 20 Oct 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 42, p. 13115-13120 6 p.

Research output: Contribution to journalArticleScientificpeer-review

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Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis

Weinert, L. A., Chaudhuri, R. R., Wang, J., Peters, S. E., Corander, J., Jombart, T., Baig, A., Howell, K. J., Vehkala, M., Valimaki, N., Harris, D., Tran Thi Bich Chieu, Nguyen Van Vinh Chau, Campbell, J., Schultsz, C., Parkhill, J., Bentley, S. D., Langford, P. R., Rycroft, A. N., Wren, B. W. & 7 othersFarrar, J., Baker, S., Ngo Thi Hoa, Holden, M. T. G., Tucker, A. W., Maskell, D. J. & BRaDP1T Consortium, Mar 2015, In : Nature Communications. 6, 9 p., 6740.

Research output: Contribution to journalArticleScientificpeer-review

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Hierarchical Bayesian Model for Rare Variant Association Analysis Integrating Genotype Uncertainty in Human Sequence Data

He, L., Pitkaniemi, J., Sarin, A-P., Salomaa, V., Sillanpaa, M. J. & Ripatti, S., Feb 2015, In : Genetic Epidemiology. 39, 2, p. 89-100 12 p.

Research output: Contribution to journalArticleScientificpeer-review

K-Pax2: Bayesian identification of cluster-defining amino acid positions in large sequence datasets

Pessia, A., Grad, Y., Cobey, S., Puranen, J. S. & Corander, J., 15 Jul 2015, In : Microbial Genomics. 1, 1, 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Labeled directed acyclic graphs: a generalization of context-specific independence in directed graphical models

Pensar, J., Nyman, H., Koski, T. & Corander, J., Mar 2015, In : Data Mining and Knowledge Discovery. 29, 2, p. 503-533 31 p.

Research output: Contribution to journalArticleScientificpeer-review

MCMC-Driven Adaptive Multiple Importance Sampling

Martino, L., Elvira, V., Luengo, D. & Corander, J., 2015, INTERDISCIPLINARY BAYESIAN STATISTICS, EBEB 2014. Polpo, A., Louzada, F., Rifo, LLR., Stern, JM. & Lauretto, M. (eds.). Springer, p. 97-109 13 p. (Springer Proceedings in Mathematics & Statistics; vol. 118).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Metabolite Profiling and Cardiovascular Event Risk A Prospective Study of 3 Population-Based Cohorts

Wurtz, P., Havulinna, A. S., Soininen, P., Tynkkynen, T., Prieto-Merino, D., Tillin, T., Ghorbani, A., Artati, A., Wang, Q., Tiainen, M., Kangas, A. J., Kettunen, J., Kaikkonen, J., Mikkila, V., Jula, A., Kahonen, M., Lehtimaki, T., Lawlor, D. A., Gaunt, T. R., Hughes, A. D. & 13 othersSattar, N., Illig, T., Adamski, J., Wang, T. J., Perola, M., Ripatti, S., Vasan, R. S., Raitakari, O. T., Gerszten, R. E., Casas, J-P., Chaturvedi, N., Ala-Korpela, M. & Salomaa, V., 3 Mar 2015, In : Circulation . 131, 9, p. 774-U52 37 p.

Research output: Contribution to journalArticleScientificpeer-review

Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans

Huffman, J. E., Albrecht, E., Teumer, A., Mangino, M., Kapur, K., Johnson, T., Kutalik, Z., Pirastu, N., Pistis, G., Lopez, L. M., Haller, T., Salo, P., Goel, A., Li, M., Tanaka, T., Dehghan, A., Ruggiero, D., Malerba, G., Smith, A. V., Nolte, I. M. & 100 othersPortas, L., Phipps-Green, A., Boteva, L., Navarro, P., Johansson, A., Hicks, A. A., Polasek, O., Esko, T., Peden, J. F., Harris, S. E., Murgia, F., Wild, S. H., Tenesa, A., Tin, A., Mihailov, E., Grotevendt, A., Gislason, G. K., Coresh, J., D'Adamo, P., Ulivi, S., Vollenweider, P., Waeber, G., Campbell, S., Kolcic, I., Fisher, K., Viigimaa, M., Metter, J. E., Masciullo, C., Trabetti, E., Bombieri, C., Sorice, R., Doering, A., Reischl, E., Strauch, K., Hofman, A., Uitterlinden, A. G., Waldenberger, M., Wichmann, H-E., Davies, G., Gow, A. J., Dalbeth, N., Stamp, L., Smit, J. H., Kirin, M., Nagaraja, R., Nauck, M., Schurmann, C., Budde, K., Farrington, S. M., Theodoratou, E., Jula, A., Salomaa, V., Sala, C., Hengstenberg, C., Burnier, M., Maegi, R., Klopp, N., Kloiber, S., Schipf, S., Ripatti, S., Cabras, S., Soranzo, N., Homuth, G., Nutile, T., Munroe, P. B., Hastie, N., Campbell, H., Rudan, I., Cabrera, C., Haley, C., Franco, O. H., Merriman, T. R., Gudnason, V., Pirastu, M., Penninx, B. W., Snieder, H., Metspalu, A., Ciullo, M., Pramstaller, P. P., van Duijn, C. M., Ferrucci, L., Gambaro, G., Deary, I. J., Dunlop, M. G., Wilson, J. F., Gasparini, P., Gyllensten, U., Spector, T. D., Wright, A. F., Hayward, C., Watkins, H., Perola, M., Bochud, M., Kao, W. H. L., Caulfield, M., Toniolo, D., Voelzke, H., Gieger, C., Koettgen, A. & Vitart, V., 26 Mar 2015, In : PLoS One. 10, 3, 21 p., 0119752.

Research output: Contribution to journalArticleScientificpeer-review

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Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe

Mattila, J., Havula, E., Suominen, E., Teesalu, M., Surakka, I., Hynynen, R., Kilpinen, H., Vaananen, J., Hovatta, I., Kakela, R., Ripatti, S., Sandmann, T. & Hietakangas, V., 13 Oct 2015, In : Cell Reports. 13, 2, p. 350-364 15 p.

Research output: Contribution to journalArticleScientificpeer-review

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New genetic loci link adipose and insulin biology to body fat distribution

Shungin, D., Winkler, T. W., Croteau-Chonka, D. C., Ferreira, T., Lockes, A. E., Maegi, R., Strawbridge, R. J., Pers, T. H., Fischer, K., Justice, A. E., Workalemahu, T., Wu, J. M. W., Buchkovich, M. L., Heard-Costa, N. L., Roman, T. S., Drong, A. W., Song, C., Gustafsson, S., Day, F. R., Esko, T. & 401 othersFall, T., Kutalik, Z., Luan, J., Randall, J. C., Scherag, A., Vedantam, S., Wood, A. R., Chen, J., Fehrmann, R., Karjalainen, J., Kahali, B., Liu, C-T., Schmidt, E. M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bragg-Gresham, J. L., Buyske, S., Demirkan, A., Ehret, G. B., Feitosa, M. F., Goel, A., Jackson, A. U., Johnson, T., Kleber, M. E., Kristiansson, K., Mangino, M., Leach, I. M., Medina-Gomez, C., Palmer, C. D., Pasko, D., Pechlivaniss, S., Peters, M. J., Prokopenko, I., Stancakova, A., Sung, Y. J., Tanakam, T., Teumer, A., Van Vliet-Ostaptchouk, J. V., Yengo, L., Zhang, W., Albrecht, E., Arnlov, J., Arscott, G. M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A. J., Berne, C., Blueher, M., Buhringer, S., Bonnet, F., Boettcher, Y., Bruinenberg, M., Carba, D. B., Caspersen, I. H., Clarke, R., Daw, E. W., Deelen, J., Deelman, E., Delgado, G., Doney, A. S. F., Eklund, N., Erdos, M. R., Estrada, K., Eury, E., Friedrichs, N., Garcia, M. E., Giedraitis, V., Gigante, B., Go, A. S., Golay, A., Grallert, H., Grammer, T. B., Graessler, J., Grewal, J., Groves, C. J., Haller, T., Hallmans, G., Hartman, C. A., Hassinen, M., Hayward, C., Heikkila, K., Herzig, K-H., Helmer, Q., Hillege, H. L., Holmen, O., Hunt, S. C., Isaacs, A., Ittermann, T., James, A. L., Johansson, I., Juliusdottir, T., Kalafati, I-P., Kinnunen, L., Koenig, W., Kooner, I. K., Kratzer, W., Lamina, C., Leander, K., Lee, N. R., Lichtner, P., Lind, L., Lindstrom, J., Lobbens, S., Lorentzon, M., Mach, F., Magnusson, P. K. E., Mahajan, A., McArdle, W. L., Menni, C., Merger, S., Mihailov, E., Milani, L., Mills, R., Moayyeri, A., Monda, K. L., Mooijaart, S. P., Muehleisen, T. W., Mulas, A., Mueller, G., Mueller-Nurasyid, M., Nagaraja, R., Nalls, M. A., Narisu, N., Glorioso, N., Nolte, I. M., Olden, M., Rayner, N. W., Renstrom, F., Ried, J. S., Robertson, N. R., Rose, L. M., Sanna, S., Scharnagl, H., Scholtens, S., Sennblad, B., Seufferlein, T., Sitlani, C. M., Smith, A. V., Stirrups, K., Stringham, H. M., Sundstrom, J., Swertz, M. A., Swift, A. J., Syvanen, A-C., Tayo, B. O., Thorand, B., Thorleifsson, G., Tomaschitz, A., Troffa, C., van Oort, F. V. A., Verweij, N., Vonk, J. M., Waite, L. L., Wennauer, R., Wilsgaard, T., Wojczynski, M. K., Wong, A., Zhang, Q., Zhao, J. H., Brennan, E. P., Choi, M., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Gharavi, A. G., Hedman, A. K., Hivert, M-F., Huang, J., Kanoni, S., Karpe, F., Keildson, S., Kiryluk, K., Liang, L., Lifton, R. P., Ma, B., McKnight, A. J., McPherson, R., Metspalu, A., Min, J. L., Moffatt, M. F., Montgomery, G. W., Murabito, J. M., Nicholson, G., Nyholt, D. R., Olsson, C., Perry, J. R. B., Reinmaa, E., Salem, R. M., Sandholm, N., Schadt, E. E., Scott, R. A., Stolk, L., Vallejo, E. E., Westra, H-J., Zondervan, K. T., Amouyel, P., Arveiler, D., Bakker, S. J. L., Beilby, J., Bergman, R. N., Blangero, J., Brown, M. J., Burnier, M., Campbell, H., Chakravarti, A., Chiness, P. S., Claudi-Boehmi, S., Collins, F. S., Crawford, D. C., Danesh, J., de Faire, U., de Geusl, E. J. C., Doerr, M., Erbel, R., Eriksson, J. G., Farrall, M., Ferrannini, E., Ferrieres, J., Forouhi, N. G., Forrester, T., Franco, O. H., Gansevoort, R. T., Gieger, C., Gudnason, V., Haiman, C. A., Harris, T. B., Hattersley, A. T., Heliovaara, M., Hicks, A. A., Hingorani, A. D., Hoffmann, W., Hofman, A., Homuth, G., Humphries, S. E., Hyppoenen, E., Illig, T., Jarvelin, M-R., Johansen, B., Jousilahti, P., Jula, A. M., Kaprio, J., Kee, F., Keinanen-Kiukaanniemi, S. M., Kooner, J. S., Kooperberg, C., Kovacs, P., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Lakka, T. A., Langenberg, C., Le Marchand, L., Lehtimaki, T., Lyssenko, V., Mannisto, S., Marette, A., Matise, T. C., McKenzie, C. A., McKnight, B., Musk, A. W., Mohlenkamp, S., Morris, A. D., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Palmer, L. J., Penninx, B. W., Peters, A., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ridker, P. M., Ritchie, M. D., Rudan, I., Salomaa, V., Samani, N. J., Saramies, J., Sarzynski, M. A., Schwarz, P. E. H., Shuldiner, A. R., Staessen, J. A., Steinthorsdottir, V., Stolk, R. P., Strauch, K., Toenjes, A., Tremblay, A., Tremoli, E., Vohl, M-C., Voelker, U., Vollenweider, P., Wilson, J. F., Witteman, J. C., Adair, L. S., Bochud, M., Boehm, B. O., Bornstein, S. R., Bouchard, C., Cauchi, S., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Cooper, R. S., Dedoussis, G., Ferrucci, L., Froguel, P., Grabe, H-J., Hamsten, A., Hui, J., Hveem, K., Joeckel, K-H., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Maerz, W., Munroe, P. B., Njolstad, I., Oostra, B. A., Palmer, C. N. A., Pedersen, N. L., Perola, M., Perusse, L., Peters, U., Power, C., Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T. E., Saleheen, D., Sinisalo, J., Slagboom, P. E., Snieder, H., Spector, T. D., Thorsteinsdottir, U. R., Stumvoll, M., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., van der Harst, P., Veronesi, G., Walker, M., Wareham, N. J., Watkins, H., Wichmann, H-E., Abecasis, G. R., Assimes, T. L., Berndt, S. I., Boehnkes, M., Borecki, I. B., Deloukas, P., Franke, L., Frayling, T. M., Groop, L. C., Hunter, D. J., Kaplan, R. C., O'Connell, J. R., Qi, L., Schlessinger, D., Strachan, D. P., Stefansson, K., van Dujin, C. M., Willer, C. J., Visscher, P. M., Yang, J., Hirschhorn, J. N., Zillikens, M. C., McCarthy, M. I., Speliotes, E. K., North, K. E., Fox, C. S., Barroso, I., Franks, P. W., Ingelsson, E., Heid, I. M., Loos, R. J. F., Cupples, L. A., Morris, A. P., Lindgren, C. M., Mohlke, K. L., ADIPOGEN Consortium, CARDIOGRAMplusC4D Consortium, CKDGen Consortium, GEFOS Consortium, GENIE Consortium, GLGC, ICBP, Int Endogene Consortium, LifeLines Cohort Study, MAGIC Investigators, MuTHER Consortium, PAGE Consortium, ReproGen Consortium, Lokki, M-L. & Ripatti, S. O., 12 Feb 2015, In : Nature. 518, 7538, p. 187-U378 22 p.

Research output: Contribution to journalArticleScientificpeer-review

Novel R Pipeline for Analyzing Biolog Phenotypic Microarray Data

Vehkala, M., Shubin, M., Connor, T. R., Thomson, N. R. & Corander, J., 18 Mar 2015, In : PLoS One. 10, 3, p. 1-14 14 p., 0118392.

Research output: Contribution to journalArticleScientificpeer-review

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Novel staphylococcal species that form part of a Staphylococcus aureus-related complex: the non-pigmented Staphylococcus argenteus sp nov and the non-human primate-associated Staphylococcus schweitzeri sp nov.

Tong, S. Y. C., Schaumburg, F., Ellington, M. J., Corander, J., Pichon, B., Leendertz, F., Bentley, S. D., Parkhill, J., Holt, D. C., Peters, G. & Giffard, P. M., Jan 2015, In : International Journal of Systematic and Evolutionary Microbiology. 65, p. 15-22 8 p.

Research output: Contribution to journalArticleScientificpeer-review

On the Exact Volume of Metric Balls in Complex Grassmann Manifolds

Pitaval, R-A., Wei, L., Tirkkonen, O. & Corander, J., 2015, 2015 IEEE INFORMATION THEORY WORKSHOP - FALL (ITW). New York: IEEE, p. 297-301 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

On the Finite-SNR Diversity-Multiplexing Tradeoff in Large Rayleigh Product Channels

Zheng, Z., Wei, L., Speicher, R., Mueller, R., Hamalainen, J. & Corander, J., 2015, 2015 IEEE INTERNATIONAL SYMPOSIUM ON INFORMATION THEORY (ISIT): Hong Kong Convention and Exhibition Centre, Hong Kong, 14-19 June 2015, Proceedings. Piscataway, NJ, p. 2593-2597 5 p. (IEEE International Symposium on Information Theory).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

On the Outage Capacity of Orthogonal Space-Time Block Codes Over Multi-Cluster Scattering MIMO Channels

Wei, L., Zheng, Z., Corander, J. & Taricco, G., May 2015, In : IEEE Transactions on Communications. 63, 5, p. 1700-1711 12 p.

Research output: Contribution to journalArticleScientificpeer-review

On the Volume of a Metric Ball in Unitary Group

Wei, L., Pitaval, R-A., Corander, J. & Tirkkonen, O., 2015, 2015 IEEE INTERNATIONAL SYMPOSIUM ON INFORMATION THEORY (ISIT): Hong Kong Convention and Exhibition Centre, Hong Kong, 14-19 June 2015, Proceedings. Piscataway, NJ, p. 191-195 5 p. (IEEE International Symposium on Information Theory).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

PARALLEL INTERACTING MARKOV ADAPTIVE IMPORTANCE SAMPLING

Martino, L., Elvira, V., Luengo, D. & Corander, J., 2015, 2015 23RD EUROPEAN SIGNAL PROCESSING CONFERENCE (EUSIPCO). IEEE, p. 499-503 5 p. (European Signal Processing Conference).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Patterns of genome evolution that have accompanied host adaptation in Salmonella

Langridge, G. C., Fookes, M., Connor, T. R., Feltwell, T., Feasey, N., Parsons, B. N., Seth-Smith, H. M. B., Barquist, L., Stedman, A., Humphrey, T., Wigley, P., Peters, S. E., Maskell, D. J., Corander, J., Chabalgoity, J. A., Barrow, P., Parkhill, J., Dougan, G. & Thomson, N. R., 20 Jan 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 3, p. 863-868 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Pharmacogenomics of Hypertension: A Genome-Wide, Placebo-Controlled Cross-Over Study, Using Four Classes of Antihypertensive Drugs

Hiltunen, T. P., Donner, K. M., Sarin, A-P., Saarela, J., Ripatti, S., Chapman, A. B., Gums, J. G., Gong, Y., Cooper-DeHoff, R. M., Frau, F., Glorioso, V., Zaninello, R., Salvi, E., Glorioso, N., Boerwinkle, E., Turner, S. T., Johnson, J. A. & Kontula, K. K., Jan 2015, In : Journal of the American Heart Association. 4, 1, 26 p., 001521.

Research output: Contribution to journalArticleScientificpeer-review

Population Biology of Intestinal Enterococcus Isolates from Hospitalized and Nonhospitalized Individuals in Different Age Groups

Tedim, A. P., Ruiz-Garbajosa, P., Corander, J., Rodriguez, C. M., Canton, R., Willems, R. J., Baquero, F. & Coque, T. M., Mar 2015, In : Applied and Environmental Microbiology. 81, 5, p. 1820–1831 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Posterior Predictive Comparisons for the Two-sample Problem

Blomstedt, P. & Corander, J., 2015, In : Communications in Statistics: Theory and Methods. 44, 2, p. 376-389 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Probe Region Expression Estimation for RNA-Seq Data for Improved Microarray Comparability

Uziela, K. & Honkela, A., 12 May 2015, In : PLoS One. 10, 5, 18 p., 0126545.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection

Darch, S. E., McNally, A., Harrison, F., Corander, J., Barr, H. L., Paszkiewicz, K., Holden, S., Fogarty, A., Crusz, S. A. & Diggle, S. P., 12 Jan 2015, In : Scientific Reports. 5, 12 p., 7649.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

Artigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., Shrine, N., Obeidat, M., Trochet, H., McArdle, W. L., Alves, A. C., Hui, J., Zhao, J. H., Joshi, P. K., Teumer, A., Albrecht, E., Imboden, M., Rawal, R., Lopez, L. M., Marten, J. & 31 othersEnroth, S., Surakka, I., Polasek, O., Lyytikainen, L-P., Granell, R., Hysi, P. G., Flexeder, C., Mahajan, A., Beilby, J., Bosse, Y., Brandsma, C-A., Campbell, H., Gieger, C., Glaeser, S., Gonzalez, J. R., Grallert, H., Hammond, C. J., Harris, S. E., Hartikainen, A-L., Heliovaara, M., Henderson, J., Hocking, L., Horikoshi, M., Hutri-Kahonen, N., Ingelsson, E., Johansson, A., Kemp, J. P., Kolcic, I., Kumar, A., Ripatti, S. & UK BiLEVE, Dec 2015, In : Nature Communications. 6, 12 p., 8658.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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SMELLY PARALLEL MCMC CHAINS

Martino, L., Elvira, V., Luengo, D., Artes-Rodriguez, A. & Corander, J., 2015, 2015 IEEE INTERNATIONAL CONFERENCE ON ACOUSTICS, SPEECH, AND SIGNAL PROCESSING (ICASSP). p. 4070-4074 5 p. (International Conference on Acoustics Speech and Signal Processing ICASSP).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Targeted Resequencing of the Pericentromere of Chromosome 2 Linked to Constitutional Delay of Growth and Puberty

Cousminer, D. L., Leinonen, J. T., Sarin, A-P., Chheda, H., Surakka, I., Wehkalampi, K., Ellonen, P., Ripatti, S., Dunkel, L., Palotie, A. & Widen, E., 1 Jun 2015, In : PLoS One. 10, 6, 16 p., 0128524.

Research output: Contribution to journalArticleScientificpeer-review

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The Biomarker GlycA is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

Ritchie, S. C., Würtz, P., Nath, A. P., Abraham, G., Havulinna, A. S., Fearnley, L. G., Sarin, A-P., Kangas, A. J., Soininen, P., Aalto, K., Seppälä, I., Raitoharju, E., Salmi, M., Maksimow, M., Männistö, S., Kähönen, M., Juonala, M., Ripatti, S., Lehtimäki, T., Jalkanen, S. & 6 othersPerola, M., Raitakari, O., Salomaa, V., Ala-Korpela, M., Kettunen, J. & Inouye, M., 2015, In : Cell Systems. 1, 4, p. 293-301 9 p.

Research output: Contribution to journalArticleScientificpeer-review

The fine-scale genetic structure of the British population

Leslie, S., Winney, B., Hellenthal, G., Davison, D., Boumertit, A., Day, T., Hutnik, K., Royrvik, E. C., Cunliffe, B., Lawson, D. J., Falush, D., Freeman, C., Pirinen, M., Myers, S., Robinson, M., Donnelly, P., Bodmer, W., Wellcome Trust Case Control & Int Multiple Sclerosis Genetics, 19 Mar 2015, In : Nature. 519, 7543, p. 309-+ 24 p.

Research output: Contribution to journalArticleScientificpeer-review

The impact of low-frequency and rare variants on lipid levels

Surakka, I., Horikoshi, M., Magi, R., Sarin, A-P., Mahajan, A., Lagou, V., Marullo, L., Ferreira, T., Miraglio, B., Timonen, S., Kettunen, J., Pirinen, M., Karjalainen, J., Thorleifsson, G., Hagg, S., Hottenga, J-J., Isaacs, A., Ladenvall, C., Beekman, M., Esko, T. & 31 othersRied, J. S., Nelson, C. P., Willenborg, C., Gustafsson, S., Westra, H-J., Blades, M., de Craen, A. J. M., de Geus, E. J., Deelen, J., Grallert, H., Hamsten, A., Havulinna, A. S., Hengstenberg, C., Houwing-Duistermaat, J. J., Hypponen, E., Karssen, L. C., Lehtimaki, T., Lyssenko, V., Magnusson, P. K. E., Mihailov, E., Mpindi, J-P., Perola, M., Kaprio, J., Groop, L., Eriksson, J. G., Ikonen, E., Kallioniemi, O., Pietiainen, V., Palotie, A., Ripatti, S. & ENGAGE Consortium, Jun 2015, In : Nature Genetics. 47, 6, p. 589-597 9 p.

Research output: Contribution to journalArticleScientificpeer-review

The landscape of genomic imprinting across diverse adult human tissues

Baran, Y., Subramaniam, M., Biton, A., Tukiainen, T., Tsang, E. K., Rivas, M. A., Pirinen, M., Gutierrez-Arcelus, M., Smith, K. S., Kukurba, K. R., Zhang, R., Eng, C., Torgerson, D. G., Urbanek, C., Li, J. B., Rodriguez-Santana, J. R., Burchard, E. G., Seibold, M. A., MacArthur, D. G., Montgomery, S. B. & 3 othersZaitlen, N. A., Lappalainen, T. & GTEx Consortium, Jul 2015, In : Genome Research. 25, 7, p. 927-936 10 p.

Research output: Contribution to journalArticleScientificpeer-review

The transcriptional landscape of age in human peripheral blood

Peters, M. J., Joehanes, R., Pilling, L. C., Schurmann, C., Conneely, K. N., Powell, J., Reinmaa, E., Sutphin, G. L., Zhernakova, A., Schramm, K., Wilson, Y. A., Kobes, S., Tukiainen, T., Ramos, Y. F., Goering, H. H. H., Fornage, M., Liu, Y., Gharib, S. A., Stranger, B. E., De Jager, P. L. & 31 othersAviv, A., Levy, D., Murabito, J. M., Munson, P. J., Huan, T., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., van Rooij, J., Stolk, L., Broer, L., Verbiest, M. M. P. J., Jhamai, M., Arp, P., Metspalu, A., Tserel, L., Milani, L., Samani, N. J., Peterson, P., Kasela, S., Codd, V., Peters, A., Ward-Caviness, C. K., Herder, C., Waldenberger, M., Roden, M., Hovatta, I., Perola, M., Ripatti, S., Kettunen, J. & NABEC UKBEC Consortium, Oct 2015, In : Nature Communications. 6, 14 p., 8570.

Research output: Contribution to journalArticleScientificpeer-review

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Women's and men's sexual preferences and activities with respect to the partner's age: evidence for female choice

Antfolk, J., Salo, B., Alanko, K., Bergen, E., Corander, J., Sandnabba, N. K. & Santtila, P., Jan 2015, In : Evolution and Human Behavior. 36, 1, p. 73-79 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2014

Acinetobacter in the skin microbiota protects from atopic sensitisation

Fyhrquist, N. T., Ruokolainen, L., Suomalainen, A., Lehtimaki, S., Veckman, V., Vendelin, J., Karisola, P., Savinko, T., Lehto, M., Jarva, H., Kosunen, T., Corander, J., Petri, A., von Hertzen, L., Laatikainen, T., Mäkelä, M., Haahtela, T., Greco, D., Hanski & Alenius, H., Sep 2014, In : Allergy : European journal of allergy and clinical immunology. 69, p. 4-5 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Acinetobacter species in the skin microbiota protect against allergic sensitization and inflammation

Fyhrquist, N., Ruokolainen, L., Suomalainen, A., Lehtimaki, S., Veckman, V., Vendelin, J., Karisola, P., Lehto, M., Savinko, T., Jarva, H., Kosunen, T. U., Corander, J., Auvinen, P., Paulin, L., von Hertzen, L., Laatikainen, T., Mäkelä, M., Haahtela, T., Greco, D., Hanski, I. & 1 othersAlenius, H., Dec 2014, In : Journal of Allergy and Clinical Immunology. 134, 6, p. 1301-1320 20 p.

Research output: Contribution to journalArticleScientificpeer-review

A community effort to assess and improve drug sensitivity prediction algorithms

Costello, J. C., Heiser, L. M., Georgii, E., Gonen, M., Menden, M. P., Wang, N. J., Bansal, M., Ammad-ud-din, M., Hintsanen, P., Khan, S. A., Mpindi, J-P., Kallioniemi, O., Honkela, A., Aittokallio, T., Wennerberg, K., Collins, J. J., Gallahan, D., Singer, D., Saez-Rodriguez, J., Kaski, S. & 3 othersGray, J. W., Stolovitzky, G. & NCI DREAM Community, Dec 2014, In : Nature Biotechnology. 32, 12, p. 1202-U57 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Addition chains meet postage stamps: reducing the number of multiplications

Kohonen, J. & Corander, J., 15 Feb 2014, In : Journal of Integer Sequences. 17, 3, 13 p., 14.3.4.

Research output: Contribution to journalArticleScientificpeer-review

A genome-wide association study of anorexia nervosa

Boraska, V., Franklin, C. S., Floyd, J. A. B., Thornton, L. M., Huckins, L. M., Southam, L., Rayner, N. W., Tachmazidou, I., Klump, K. L., Treasure, J., Lewis, C. M., Schmidt, U., Tozzi, F., Kiezebrink, K., Hebebrand, J., Gorwood, P., Adan, R. A. H., Kas, M. J. H., Favaro, A., Santonastaso, P. & 156 othersFernandez-Aranda, F., Gratacos, M., Rybakowski, F., Dmitrzak-Weglarz, M., Kaprio, J., Keski-Rahkonen, A., Raevuori, A., Van Furth, E. F., 't Landt, M. C. T. S-O., Hudson, J. I., Reichborn-Kjennerud, T., Knudsen, G. P. S., Monteleone, P., Kaplan, A. S., Karwautz, A., Hakonarson, H., Berrettini, W. H., Guo, Y., Li, D., Schork, N. J., Komaki, G., Ando, T., Inoko, H., Esko, T., Fischer, K., Maennik, K., Metspalu, A., Baker, J. H., Cone, R. D., Dackor, J., DeSocio, J. E., Hilliard, C. E., O'Toole, J. K., Pantel, J., Szatkiewicz, J. P., Taico, C., Zerwas, S., Trace, S. E., Davis, O. S. P., Helder, S., Buehren, K., Burghardt, R., de Zwaan, M., Egberts, K., Ehrlich, S., Herpertz-Dahlmann, B., Herzog, W., Imgart, H., Scherag, A., Scherag, S., Zipfel, S., Boni, C., Ramoz, N., Versini, A., Brandys, M. K., Danner, U. N., de Kovel, C., Hendriks, J., Koeleman, B. P. C., Ophoff, R. A., Strengman, E., van Elburg, A. A., Bruson, A., Clementi, M., Degortes, D., Forzan, M., Tenconi, E., Docampo, E., Escaramis, G., Jimenez-Murcia, S., Lissowska, J., Rajewski, A., Szeszenia-Dabrowska, N., Slopien, A., Hauser, J., Karhunen, L., Meulenbelt, I., Slagboom, P. E., Tortorella, A., Maj, M., Dedoussis, G., Dikeos, D., Gonidakis, F., Tziouvas, K., Tsitsika, A., Papezova, H., Slachtova, L., Martaskova, D., Kennedy, J. L., Levitan, R. D., Yilmaz, Z., Huemer, J., Koubek, D., Merl, E., Wagner, G., Lichtenstein, P., Breen, G., Cohen-Woods, S., Farmer, A., McGuffin, P., Cichon, S., Giegling, I., Herms, S., Rujescu, D., Schreiber, S., Wichmann, H-E., Dina, C., Sladek, R., Gambaro, G., Soranzo, N., Julia, A., Marsal, S., Rabionet, R., Gaborieau, V., Dick, D. M., Palotie, A., Ripatti, S., Widen, E., Andreassen, O. A., Espeseth, T., Lundervold, A., Reinvang, I., Steen, V. M., Le Hellard, S., Mattingsdal, M., Ntalla, I., Bencko, V., Foretova, L., Janout, V., Navratilova, M., Gallinger, S., Pinto, D., Scherer, S. W., Aschauer, H., Carlberg, L., Schosser, A., Alfredsson, L., Ding, B., Klareskog, L., Padyukov, L., Courtet, P., Guillaume, S., Jaussent, I., Finan, C., Kalsi, G., Roberts, M., Logan, D. W., Peltonen, L., Ritchie, G. R. S., Barrett, J. C., Estivill, X., Hinney, A., Sullivan, P. F., Collier, D. A., Zeggini, E. & Bulik, C. M., Oct 2014, In : Molecular Psychiatry. 19, 10, p. 1085-1094 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Allele-specific regulation of DISC1 expression by miR-135b-5p

Rossi, M., Kilpinen, L. H., Muona, M., Surakka, I., Ingle, C., Lahtinen, J., Hennah, W., Ripatti, S. & Hovatta, I., Jun 2014, In : European Journal of Human Genetics. 22, 6, p. 840-843 4 p.

Research output: Contribution to journalArticleScientificpeer-review

AN ADAPTIVE POPULATION IMPORTANCE SAMPLER

Martino, L., Elvira, V., Luengo, D. & Corander, J., 2014, Unknown host publication. 5 p. (International Conference on Acoustics Speech and Signal Processing ICASSP).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression

Marttinen, P., Pirinen, M., Sarin, A-P., Gillberg, J., Kettunen, J., Surakka, I., Kangas, A. J., Soininen, P., O'Reilly, P., Kaakinen, M., Kahonen, M., Lehtimaki, T., Ala-Korpela, M., Raitakari, O. T., Salomaa, V., Jarvelin, M-R., Ripatti, S. & Kaski, S., 15 Jul 2014, In : Bioinformatics. 30, 14, p. 2026-2034 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

Vimaleswaran, K. S., Cavadino, A., Berry, D. J., Jorde, R., Dieffenbach, A. K., Lu, C., Alves, A. C., Heerspink, H. J. L., Tikkanen, E., Eriksson, J., Wong, A., Mangino, M., Jablonski, K. A., Nolte, I. M., Houston, D. K., Ahluwalia, T. S., van der Most, P. J., Pasko, D., Zgaga, L., Thiering, E. & 34 othersVitart, V., Fraser, R. M., Huffman, J. E., de Boer, R. A., Schoettker, B., Saum, K-U., McCarthy, M. I., Dupuis, J., Herzig, K-H., Sebert, S., Pouta, A., Laitinen, J., Kleber, M. E., Navis, G., Lorentzon, M., Jameson, K., Arden, N., Cooper, J. A., Acharya, J., Hardy, R., Raitakari, O., Ripatti, S., Billings, L. K., Lahti, J., Osmond, C., Penninx, B. W., Rejnmark, L., Lohman, K. K., Eriksson, J. G., Kivimaki, M., LifeLines Cohort Study Investigato, ICBP, CHARGE Consortium & Global Blood Pressure Genetics Gl, Sep 2014, In : The Lancet diabetes & endocrinology. 2, 9, p. 719-729 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Bayesian clustering of DNA sequences using Markov chains and a stochastic partition model

Jääskinen, V., Parkkinen, V., Cheng, L. & Corander, J., Feb 2014, In : Statistical applications in genetics and molecular biology. 13, 1, p. 105-121 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Bayesian Latent Variable Collapsing Model for Detecting Rare Variant Interaction Effect in Twin Study

He, L., Sillanpaa, M. J., Ripatti, S. & Pitkaniemi, J., May 2014, In : Genetic Epidemiology. 38, 4, p. 310-324 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Bayesian predictive modeling and comparison of oil samples

Blomstedt, P., Gauriot, R., Viitala, N., Reinikainen, T. & Corander, J., Jan 2014, In : Journal of Chemometrics. 28, 1, p. 52-59 8 p.

Research output: Contribution to journalArticleScientificpeer-review