Publications 2001 2020

2013

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

Fall, T., Hagg, S., Maegi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A-P., Thorleifsson, G., Ladenvall, C., Kals, M., Kuningas, M., Draisma, H. H. M., Ried, J. S., van Zuydam, N. R., Huikari, V., Mangino, M., Sonestedt, E., Benyamin, B., Nelson, C. P., Rivera, N. V. & 31 othersKristiansson, K., Shen, H., Havulinna, A. S., Dehghan, A., Donnelly, L. A., Kaakinen, M., Nuotio, M-L., Robertson, N., de Bruijn, R. F. A. G., Ikram, M. A., Amin, N., Balmforth, A. J., Braund, P. S., Doney, A. S. F., Doering, A., Elliott, P., Esko, T., Franco, O. H., Gretarsdottir, S., Hartikainen, A-L., Heikkilä, K. V., Herzig, K-H., Holm, H., Hottenga, J. J., Hypponen, E., Kettunen, J., Kaprio, J., Tuomi, T., Groop, L., Ripatti, S. & ENGAGE Consortium, Jun 2013, In : PLoS Medicine. 10, 6, p. e1001474 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Urban particle number concentration forecast model evaluation

Mölgaard, B., Birmili, W., Clifford, S., Massling, A., Eleftheriadis, K., Norman, M., Vratolis, S., Wehner, B., Corander, J., Hämeri, K. & Hussein, T., 2013, Proceedings of FCoE in 'Physics, Chemistry, Biology and Meteorology of Atmospheric Composition and Climate Change' Annual Meeting 2013. p. 403-404 2 p. (Report Series in Aerosol Science; vol. Nro 142 (2013)).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientific

Using Bayes' theorem in behavioural crime linking of serial homicide

Salo, B., Siren, J., Corander, J., Zappala, A., Bosco, D., Mokros, A. & Santtila, P., Sep 2013, In : Legal and Criminological Psychology. 18, 2, p. 356-370 15 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

A common variant near the KCNJ2 gene is associated with T-peak to T-end interval

Marjamaa, A., Oikarinen, L., Porthan, K., Ripatti, S., Peloso, G., Noseworthy, P. A., Viitasalo, M., Nieminen, M. S., Kontula, K., Toivonen, L., Palotie, L., Havulinna, A. S., Jula, A., O'Donnell, C. J., Newton-Cheh, C., Perola, M. & Salomaa, V., 2012, In : Heart rhythm.. 9, 7, p. 1099-1103 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

Soronen, J., Laurila, P-P., Naukkarinen, J., Surakka, I., Ripatti, S., Jauhiainen, M., Olkkonen, V. M. & Yki-Järvinen, H., 2012, In : BMC Medical Genomics. 5, 9, p. Article Number: 9 13 p.

Research output: Contribution to journalArticleScientificpeer-review

A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans

Palmer, N. D., McDonough, C. W., Hicks, P. J., Roh, B. H., Wing, M. R., An, S. S., Hester, J. M., Cooke, J. N., Bostrom, M. A., Rudock, M. E., Talbert, M. E., Lewis, J. P., Ferrara, A., Lu, L., Ziegler, J. T., Sale, M. M., Divers, J., Shriner, D., Adeyemo, A., Rotimi, C. N. & 8 othersNg, M. C. Y., Langefeld, C. D., Freedman, B. I., Bowden, D. W., DIAGRAM Consortium, MAGIC Investigators, Ripatti, S. O. & Kaprio, J., 4 Jan 2012, In : PLoS One. 7, 1, p. Article Number:e29202 14 p.

Research output: Contribution to journalArticleScientificpeer-review

A Genome-Wide Association Study of Monozygotic Twin-Pairs Suggests a Locus Related to Variability of Serum High-Density Lipoprotein Cholesterol

Surakka, I., Whitfield, J. B., Perola, M., Visscher, P. M., Montgomery, G. W., Falchi, M., Willemsen, G., de Geus, E. J. C., Magnusson, P. K. E., Christensen, K., Sorensen, T. I. A., Pietiläinen, K. H., Rantanen, T., Silander, K., Widen, E., Muilu, J., Rahman, I., Liljedahl, U., Syvanen, A-C., Palotie, A. & 9 othersKaprio, J., Kyvik, K. O., Pedersen, N. L., Boomsma, D. I., Spector, T., Martin, N. G., Ripatti, S., Palotie, L. & GenomEUtwin Project, Dec 2012, In : Twin Research and Human Genetics. 15, 6, p. 691-699 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Analysis of Detailed Phenotype Profiles Reveals CHRNA5-CHRNA3-CHRNB4 Gene Cluster Association With Several Nicotine Dependence Traits

Broms, U., Wedenoja, J., Largeau, M. R., Korhonen, T., Pitkäniemi, J. M., Keskitalo, K., Happola, A., Heikkila, K. H., Heikkila, K., Ripatti, S., Sarin, A-P., Salminen, O., Paunio, T., Pergadia, M. L., Madden, P. A. F., Kaprio, J. & Loukola, A., 2012, In : Nicotine & Tobacco Research. 14, 6, p. 720-733 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Bayesian Adaptive Approach to Estimating Sample Sizes for Seizures of Illicit Drugs

Moroni, R., Aalberg, L., Reinikainen, T. & Corander, J., 2012, In : Journal of Forensic Sciences. 57, 1, p. 80-85 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Bayesian estimation of bacterial community composition from 454 sequencing data

Cheng, L., Walker, A. W. & Corander, J., 2012, In : Nucleic Acids Research. 40, 12, p. 5240-5249 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Bayesian Modeling with Gaussian Processes using the MATLAB Toolbox GPstuff (v3.4)

Vanhatalo, J., Riihimäki, J., Hartikainen, J., Jylänki, P., Tolvanen, V. & Vehtari, A., 5 Oct 2012, 58 p.

Research output: Book/ReportCommissioned reportProfessional

Bayesian refinement of association signals for 14 loci in 3 common diseases

Maller, J. B., McVean, G., Byrnes, J., Vukcevic, D., Palin, K., Su, Z., Howson, J. M. M., Auton, A., Myers, S., Morris, A., Pirinen, M., Brown, M. A., Burton, P. R., Caulfield, M. J., Compston, A., Farrall, M., Hall, A. S., Hattersley, A. T., Hill, A. V. S., Mathew, C. G. & 18 othersPembrey, M., Satsangi, J., Stratton, M. R., Worthington, J., Craddock, N., Hurles, M., Ouwehand, W., Parkes, M., Rahman, N., Duncanson, A., Todd, J. A., Kwiatkowski, D. P., Samani, N. J., Gough, S. C. L., McCarthy, M. I., Deloukas, P., Donnelly, P. & Wellcome Trust Case Control Consor, Dec 2012, In : Nature Genetics. 44, 12, p. 1294-1301 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Bayesian spatial multispecies modelling to assess pelagic fish stocks from acoustic- and trawl-survey data

Juntunen, T., Vanhatalo, J., Peltonen, H. & Mäntyniemi, S., 2012, In : ICES Journal of Marine Science. 69, 1, p. 95-104

Research output: Contribution to journalArticleScientificpeer-review

Clinical isolates of Yersinia enterocolitica Biotype 1A represent two phylogenetic lineages with differing pathogenicity-related properties

Sihvonen, L. M., Jalkanen, K., Huovinen, E., Toivonen, S., Corander, J., Kuusi, M., Skurnik, M., Siitonen, A. & Haukka, K., 2012, In : BMC Microbiology. 12, 24 p., 208.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Su, Z., Gay, L. J., Strange, A., Palles, C., Band, G., Whiteman, D. C., Lescai, F., Langford, C., Nanji, M., Edkins, S., van der Winkel, A., Levine, D., Sasieni, P., Bellenguez, C., Howarth, K., Freeman, C., Trudgill, N., Tucker, A. T., Pirinen, M., Peppelenbosch, M. P. & 32 othersvan der Laan, L. J. W., Kuipers, E. J., Drenth, J. P. H., Peters, W. H., Reynolds, J. V., Kelleher, D. P., McManus, R., Grabsch, H., Prenen, H., Bisschops, R., Krishnadath, K., Siersema, P. D., van Baal, J. W. P. M., Middleton, M., Petty, R., Gillies, R., Burch, N., Bhandari, P., Paterson, S., Edwards, C., Penman, I., Vaidya, K., Ang, Y., Murray, I., Patel, P., Ye, W., Mullins, P., Wu, A. H., Rautanen, A., Palotie, L., Esophageal Adenocarcinoma Genetics & Wellcome Trust Case Control Consor, Oct 2012, In : Nature Genetics. 44, 10, p. 1131-1136 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci

Tukiainen, T., Kettunen, J., Kangas, A. J., Lyytikainen, L-P., Soininen, P., Sarin, A-P., Tikkanen, E., O'Reilly, P. F., Savolainen, M. J., Kaski, K., Pouta, A., Jula, A., Lehtimaki, T., Kahonen, M., Viikari, J., Taskinen, M-R., Jauhiainen, M., Eriksson, J. G., Raitakari, O., Salomaa, V. & 5 othersJarvelin, M-R., Perola, M., Palotie, A., Ala-Korpela, M. & Ripatti, S., 2012, In : Human Molecular Genetics. 21, 6, p. 1444-1455 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Detection of recombination events in bacterial genomes from large population samples

Marttinen, P., Hanage, W. P., Croucher, N. J., Connor, T. R., Harris, S. R., Bentley, S. D. & Corander, J., 2012, In : Nucleic Acids Research. 40, 1, p. e6 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Forecasting size-fractionated particle number concentrations in the urban atmosphere

Molgaard, B., Hussein, T., Corander, J. & Hämeri, K., 2012, In : Atmospheric Environment. 46, p. 155-163 9 p.

Research output: Contribution to journalArticleScientificpeer-review

FTO genotype is associated with phenotypic variability of body mass index

Yang, J., Loos, R. J. F., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Maegi, R., Waite, L., Smith, A. V., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., Huffman, J. E. & 152 othersWang, S. R., Palmer, C., Esko, T., Fischer, K., Zhao, J. H., Demirkan, A., Isaacs, A., Feitosa, M. F., Luan, J., Heard-Costa, N. L., White, C., Jackson, A. U., Preuss, M., Ziegler, A., Eriksson, J., Kutalik, Z., Frau, F., Nolte, I. M., Van Vliet-Ostaptchouk, J. V., Hottenga, J-J., Jacobs, K. B., Verweij, N., Goel, A., Medina-Gomez, C., Estrada, K., Bragg-Gresham, J. L., Sanna, S., Sidore, C., Tyrer, J., Teumer, A., Prokopenko, I., Mangino, M., Lindgren, C. M., Assimes, T. L., Shuldiner, A. R., Hui, J., Beilby, J. P., McArdle, W. L., Hall, P., Haritunians, T., Zgaga, L., Kolcic, I., Polasek, O., Zemunik, T., Oostra, B. A., Junttila, M. J., Groenberg, H., Schreiber, S., Peters, A., Hicks, A. A., Stephens, J., Foad, N. S., Laitinen, J., Pouta, A., Kaakinen, M., Willemsen, G., Vink, J. M., Wild, S. H., Navis, G., Asselbergs, F. W., Homuth, G., John, U., Iribarren, C., Harris, T., Launer, L., Gudnason, V., O'Connell, J. R., Boerwinkle, E., Cadby, G., Palmer, L. J., James, A. L., Musk, A. W., Ingelsson, E., Psaty, B. M., Beckmann, J. S., Waeber, G., Vollenweider, P., Hayward, C., Wright, A. F., Rudan, I., Groop, L. C., Metspalu, A., Khaw, K. T., van Duijn, C. M., Borecki, I. B., Province, M. A., Wareham, N. J., Tardif, J-C., Huikuri, H. V., Cupples, L. A., Atwood, L. D., Fox, C. S., Boehnke, M., Collins, F. S., Mohlke, K. L., Erdmann, J., Schunkert, H., Hengstenberg, C., Stark, K., Lorentzon, M., Ohlsson, C., Cusi, D., Staessen, J. A., Van der Klauw, M. M., Pramstaller, P. P., Kathiresan, S., Jolley, J. D., Ripatti, S., Jarvelin, M-R., de Geus, E. J. C., Boomsma, D. I., Penninx, B., Wilson, J. F., Campbell, H., Chanock, S. J., van der Harst, P., Hamsten, A., Watkins, H., Hofman, A., Witteman, J. C., Zillikens, M. C., Uitterlinden, A. G., Rivadeneira, F., Zillikens, M. C., Kiemeney, L. A., Vermeulen, S. H., Abecasis, G. R., Schlessinger, D., Schipf, S., Stumvoll, M., Toenjes, A., Spector, T. D., North, K. E., Lettre, G., McCarthy, M. I., Berndt, S. I., Heath, A. C., Madden, P. A. F., Nyholt, D. R., Montgomery, G. W., Martin, N. G., McKnight, B., Strachan, D. P., Hill, W. G., Snieder, H., Ridker, P. M., Thorsteinsdottir, U., Stefansson, K., Frayling, T. M., Hirschhorn, J. N., Goddard, M. E. & Visscher, P. M., 11 Oct 2012, In : Nature. 490, 7419, p. 267-U178 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic Profiling Using Genome-Wide Significant Coronary Artery Disease Risk Variants Does Not Improve the Prediction of Subclinical Atherosclerosis: The Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey - A Meta-Analysis of Three Independent Studies

Hernesniemi, J. A., Seppala, I., Lyytikainen, L-P., Mononen, N., Oksala, N., Hutri-Kahonen, N., Juonala, M., Taittonen, L., Smith, E. N., Schork, N. J., Chen, W., Srinivasan, S. R., Berenson, G. S., Murray, S. S., Laitinen, T., Jula, A., Kettunen, J., Ripatti, S., Laaksonen, R., Viikari, J. & 3 othersKahonen, M., Raitakari, O. T. & Lehtimaki, T., 2012, In : PLoS One. 7, 1, p. e28931 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Fox, C. S., Liu, Y., White, C. C., Feitosa, M., Smith, A. V., Heard-Costa, N., Lohman, K., Johnson, A. D., Foster, M. C., Greenawalt, D. M., Griffin, P., Ding, J., Newman, A. B., Tylavsky, F., Miljkovic, I., Kritchevsky, S. B., Launer, L., Garcia, M., Eiriksdottir, G., Carr, J. J. & 9 othersGudnason, V., Harris, T. B., Cupples, L. A., Borecki, I. B., GIANT Consortium, MAGIC Consortium, GLGC Consortium, Ripatti, S. O. & Kaprio, J., May 2012, In : PLoS Genetics. 8, 5, p. e1002695 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

Bellenguez, C., Bevan, S., Gschwendtner, A., Spencer, C. C. A., Burgess, A. I., Pirinen, M., Jackson, C. A., Traylor, M., Strange, A., Su, Z., Band, G., Syme, P. D., Malik, R., Pera, J., Norrving, B., Lemmens, R., Freeman, C., Schanz, R., James, T., Poole, D. & 70 othersMurphy, L., Segal, H., Cortellini, L., Cheng, Y-C., Woo, D., Nalls, M. A., Mueller-Myhsok, B., Meisinger, C., Seedorf, U., Ross-Adams, H., Boonen, S., Wloch-Kopec, D., Valant, V., Slark, J., Furie, K., Delavaran, H., Langford, C., Deloukas, P., Edkins, S., Hunt, S., Gray, E., Dronov, S., Peltonen, L., Gretarsdottir, S., Thorleifsson, G., Thorsteinsdottir, U., Stefansson, K., Boncoraglio, G. B., Parati, E. A., Attia, J., Holliday, E., Levi, C., Franzosi, M-G., Goel, A., Helgadottir, A., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Worrall, B. B., Kittner, S. J., Mitchell, B. D., Kissela, B., Meschia, J. F., Thijs, V., Lindgren, A., Macleod, M. J., Slowik, A., Walters, M., Rosand, J., Sharma, P., Farrall, M., Sudlow, C. L. M., Rothwell, P. M., Dichgans, M., Donnelly, P., Markus, H. S., ISGC & WTCCC2, Mar 2012, In : Nature Genetics. 44, 3, p. 328-333 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

Kettunen, J., Tukiainen, T., Sarin, A-P., Ortega-Alonso, A., Tikkanen, E., Lyytikainen, L-P., Kangas, A. J., Soininen, P., Wuertz, P., Silander, K., Dick, D. M., Rose, R. J., Savolainen, M. J., Viikari, J., Kahonen, M., Lehtimaki, T., Pietilainen, K. H., Inouye, M., McCarthy, M. I., Jula, A. & 11 othersEriksson, J., Raitakari, O. T., Salomaa, V., Kaprio, J., Jarvelin, M-R., Peltonen, L., Perola, M., Freimer, N. B., Ala-Korpela, M., Palotie, A. & Ripatti, S., 2012, In : Nature Genetics. 44, 3, p. 269-276 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-Wide Association Study Implicates HLA-C*01:02 as a Risk Factor at the Major Histocompatibility Complex Locus in Schizophrenia

Strange, A., Riley, B. P., Spencer, C. C. A., Morris, D. W., Pirinen, M., O'Dushlaine, C. T., Su, Z., Maher, B. S., Freeman, C., Cormican, P., Bellenguez, C., Kenny, E. M., Band, G., Wormley, B., Donohoe, G., Dilthey, A., Moutsianas, L., Quinn, E., Edkins, S., Judge, R. & 34 othersColeman, K., Hunt, S., Tropea, D., Roche, S., Cummings, L., Kelleher, E., McKeon, P., Dinan, T., McDonald, C., Murphy, K. C., O'Callaghan, E., O'Neill, F. A., Waddington, J. L., Walsh, D., Giannoulatou, E., Langford, C., Deloukas, P., Gray, E., Dronov, S., Potter, S., Pearson, R., Vukcevic, D., Tashakkori-Ghanbaria, A., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Duncanson, A., Rautanen, A., Palotie, L., Irish Schizophrenia Genomics Conso, SGENE Consortium, Schizophrenia Working Grp Psychiat & Wellcome Trust Case Control Consor, 15 Oct 2012, In : Biological Psychiatry. 72, 8, p. 620-628 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide meta-analysis of common variant differences between men and women

Wellcome Trust Case Control, 1 Nov 2012, In : Human Molecular Genetics. 21, 21, p. 4805-4815 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution But No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits

Kristiansson, K., Perola, M., Tikkanen, E., Kettunen, J., Surakka, I., Havulinna, A. S., Stancakova, A., Barnes, C., Widen, E., Kajantie, E., Eriksson, J. G., Viikari, J., Kahonen, M., Lehtimaki, T., Raitakari, O. T., Hartikainen, A-L., Ruokonen, A., Pouta, A., Jula, A., Kangas, A. J. & 14 othersSoininen, P., Ala-Korpela, M., Mannisto, S., Jousilahti, P., Bonnycastle, L. L., Jarvelin, M-R., Kuusisto, J., Collins, F. S., Laakso, M., Hurles, M. E., Palotie, A., Palotie, L., Ripatti, S. & Salomaa, V., Apr 2012, In : Circulation. Cardiovascular genetics. 5, 2, p. 242-249 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Tsoi, L. C., Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, J. E., Kang, H. M., Allen, M. H., McManus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Stahle, M., Burden, A. D., Smith, C. H., Cork, M. J. & 179 othersEstivill, X., Bowcock, A. M., Krueger, G. G., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, F. O., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, R. D., Vukcevic, D., Spencer, C. C. A., Deloukas, P., Mrowietz, U., Schreiber, S., Weidinger, S., Koks, S., Kingo, K., Esko, T., Metspalu, A., Lim, H. W., Voorhees, J. J., Weichenthal, M., Wichmann, H. E., Chandran, V., Rosen, C. F., Rahman, P., Gladman, D. D., Griffiths, C. E. M., Reis, A., Kere, J., Nair, R. P., Franke, A., Barker, J. N. W. N., Abecasis, G. R., Elder, J. T., Trembath, R. C., Duffin, K. C., Helms, C., Goldgar, D., Li, Y., Paschall, J., Malloy, M. J., Pullinger, C. R., Kane, J. P., Gardner, J., Perlmutter, A., Miner, A., Feng, B. J., Hiremagalore, R., Ike, R. W., Christophers, E., Henseler, T., Ruether, A., Schrodi, S. J., Prahalad, S., Guthery, S. L., Fischer, J., Liao, W., Kwok, P., Menter, A., Lathrop, G. M., Wise, C., Begovich, A. B., Onoufriadis, A., Weale, M. E., Hofer, A., Salmhofer, W., Wolf, P., Kainu, K., Saarialho-Kere, U., Suomela, S., Badorf, P., Hueffmeier, U., Kurrat, W., Kuester, W., Lascorz, J., Moessner, R., Schuermeier-Horst, F., Staender, M., Traupe, H., Bergboer, J. G. M., den Heijer, M., van de Kerkhof, P. C., Zeeuwen, P. L. J. M., Barnes, L., Campbell, L. E., Cusack, C., Coleman, C., Conroy, J., Ennis, S., Fitzgerald, O., Gallagher, P., Irvine, A. D., Kirby, B., Markham, T., McLean, W. H. I., McPartlin, J., Rogers, S. F., Ryan, A. W., Zawirska, A., Giardina, E., Lepre, T., Perricone, C., Martin-Ezquerra, G., Pujol, R. M., Riveira-Munoz, E., Inerot, A., Naluai, A. T., Mallbris, L., Wolk, K., Leman, J., Barton, A., Warren, R. B., Young, H. S., Ricano-Ponce, I., Trynka, G., Pellett, F. J., Henschel, A., Aurand, M., Bebo, B., Gieger, C., Illig, T., Moebus, S., Joeckel, K-H., Erbe, R., Donnelly, P., Palotie, L., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Craddock, N., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., McCarthy, M. I., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Samani, N., Viswanathan, A. C., Wood, N. W., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Su, Z., Hunt, S. E., Gwilliam, R., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Perez, M. L., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P. & Wellcome Trust Case Control Consor, Collaborative Assoc Study Psoriasi, Genetic Anal Psoriasis Consortium, Psoriasis Assoc Genetics Extension, Dec 2012, In : Nature Genetics. 44, 12, p. 1341-1348 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Identifying differentially expressed transcripts from RNA-seq data with biological variation

Glaus, P., Honkela, A. & Rattray, M., 2012, In : Bioinformatics. 28, 13, p. 1721-1728 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Identifying targets of multiple co-regulating transcription factors from expression time-series by Bayesian model comparison

Titsias, M. K., Honkela, A., Lawrence, N. D. & Rattray, M., 30 May 2012, In : BMC Systems Biology. 6, 21 p., 53.

Research output: Contribution to journalArticleScientificpeer-review

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Impact of Common Variation in Bone-Related Genes on Type 2 Diabetes and Related Traits

Billings, L. K., Hsu, Y-H., Ackerman, R. J., Dupuis, J., Voight, B. F., Rasmussen-Torvik, L. J., Hercberg, S., Lathrop, M., Barnes, D., Langenberg, C., Hui, J., Fu, M., Bouatia-Naji, N., Lecoeur, C., An, P., Magnusson, P. K., Surakka, I. L., Ripatti, S., Christiansen, L., Dalgard, C. & 21 othersFolkersen, L., Grundberg, E., Eriksson, P., Kaprio, J., Kyvik, K. O., Pedersen, N. L., Borecki, I. B., Province, M. A., Balkau, B., Froguel, P., Shuldiner, A. R., Palmer, L. J., Wareham, N., Meneton, P., Johnson, T., Pankow, J. S., Karasik, D., Meigs, J. B., Kiel, D. P., Florez, J. C. & ASCOT Investigators, DIAGRAM Consortium, MuTHER Consortium, MAGIC Investigators, GEFOS Consortium, 2012, In : Diabetes. 61, 8, p. 2176-2186 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Improved Statistical Modeling of Tumor Growth and Treatment Effect in Preclinical Animal Studies with Highly Heterogeneous Responses In Vivo

Laajala, T. D., Corander, J., Saarinen, N. M., Makela, K., Savolainen, S., Suominen, M. I., Alhoniemi, E., Makela, S., Poutanen, M. & Aittokallio, T., 2012, In : Clinical Cancer Research. 18, 16, p. 4385-4396 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Including known covariates can reduce power to detect genetic effects in case-control studies

Pirinen, M., Donnelly, P. & Spencer, C. C. A., Aug 2012, In : Nature Genetics. 44, 8, p. 848-851 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L., Schwantes-An, T-H., Coon, H., Han, Y., Stephens, S. H., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Guobjartsson, D., Hansel, N. N., Jiang, C., Keskitalo-Vuokko, K. & 133 othersLiu, Z., Lyytikainen, L-P., Michel, M., Rawal, R., Hum, S., Rosenberger, A., Scheet, P., Shaffer, J. R., Teumer, A., Thompson, J. R., Vink, J. M., Vogelzangs, N., Wenzlaff, A. S., Wheeler, W., Xiao, X., Yang, B-Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T., Bennett, S., Bergen, A. W., Boyd, H. A., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y-C., Cichon, S., Couper, D., Cucca, F., Dick, D. M., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A. S., Hällfors, J. K., Han, S., Hartmann, A. M., Hayward, C., Heikkila, K., Hewitt, J. K., Hottenga, J. J., Jensen, M. K., Jousilahti, P., Kaakinen, M., Kittner, S. J., Konte, B., Korhonen, T., Landi, M-T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., McNeil, D. W., Medland, S. E., Montgomery, G. W., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M., Polasek, O., Ramos, E. M., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkarsdottir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G., Barnes, K., Bickeboeller, H., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Duan, J., Edenberg, H. J., Francks, C., Gejman, P. V., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M-R., Viikari, J., Kahonen, M., Kendler, K. S., Lehtimaki, T., Levinson, D. F., Marazita, M. L., Marchini, J., Melbye, M., Mitchell, B. D., Murray, J. C., Nothen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Sanders, A. R., Schwartz, A. G., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G. E., Thorgeirsson, T., Volzke, H., Wei, Q., Wichmann, H. -E., Amos, C. I., Breslau, N., Cannon, D. S., Ehringer, M., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Stitzel, J. A., Weiss, R. B., Kraft, P. & Bierut, L. J., 2012, In : Archives of General Psychiatry. 69, 8, p. 854-861 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Integrated Bayesian risk analysis of ecosystem management in the Gulf of Finland, the Baltic Sea: How to do it?

Helle, I., Vanhatalo, J., Rahikainen, M., Mäntyniemi, S. & Kuikka, S., 2012, Joint ICES/PICES Session I Multidisciplinary perspectives in the use (and misuse) of science and scientific advice in Marine Spatial Planning. International Council for the Exploration of the Sea, 16 p. (ICES CM; vol. I, no. 04).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientific

Itämeren suojelussa tarvitaan numeroita

Vanhatalo, J., Helle, I. & Mäntyniemi, S., 9 Feb 2012, In : Helsingin Sanomat.

Research output: Contribution to journalArticleGeneral public

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

DIAbet Genetics Replication, 1 Sep 2012, In : Nature Genetics. 44, 9, p. 991+

Research output: Contribution to journalArticleScientificpeer-review

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Morris, A. P., Voight, B. F., Teslovich, T. M., Ferreira, T., Segre, A. V., Steinthorsdottir, V., Strawbridge, R. J., Khan, H., Grallert, H., Mahajan, A., Prokopenko, I., Kang, H. M., Dina, C., Esko, T., Fraser, R. M., Kanoni, S., Kumar, A., Lagou, V., Langenberg, C., Luan, J. & 31 othersLindgren, C. M., Mueller-Nurasyid, M., Pechlivanis, S., Rayner, N. W., Scott, L. J., Wiltshire, S., Yengo, L., Kinnunen, L., Rossin, E. J., Raychaudhuri, S., Johnson, A. D., Dimas, A. S., Loos, R. J. F., Vedantam, S., Chen, H., Florez, J. C., Fox, C., Liu, C-T., Rybin, D., Couper, D. J., Kao, W. H. L., Li, M., Tikkanen, E., Forsen, T., Eriksson, J. G., Palotie, L., Tuomi, T., Isomaa, B., Tuomilehto, J., Ripatti, S. & Wellcome Trust Case Control, Meta-Anal Glucose Insulin-Related, Genetic Invest ANthropometric, Asian Genetic Epidemiology, S Asian Type 2 Diabet SAT2D, DIAbet Genetics Replication, 1 Sep 2012, In : Nature Genetics. 44, 9, p. 981-990 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Metabolic Signatures of Insulin Resistance in 7,098 Young Adults

Wurtz, P., Makinen, V-P., Soininen, P., Kangas, A. J., Tukiainen, T., Kettunen, J., Savolainen, M. J., Tammelin, T., Viikari, J. S., Ronnemaa, T., Kahonen, M., Lehtimaki, T., Ripatti, S., Raitakari, O. T., Jarvelin, M-R. & Ala-Korpela, M., 2012, In : Diabetes. 61, 6, p. 1372-1380 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

Dastani, Z., Hivert, M-F., Timpson, N., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikainen, L-P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S. & 31 othersPankow, J. S., Uh, H-W., Wu, Y., Bidulescu, A., Rasmussen-Torvik, L. J., Greenwood, C. M. T., Ladouceur, M., Grimsby, J., Manning, A. K., Liu, C-T., Kooner, J., Mooser, V. E., Vollenweider, P., Kapur, K. A., Chambers, J., Wareham, N. J., Langenberg, C., Frants, R., Willems-vanDijk, K., Oostra, B. A., Willems, S. M., Lamina, C., Winkler, T. W., Psaty, B. M., Nuotio, M-L., Perola, M., Eriksson, J. G., GLGC Investigators, DIAGRAM Consortium, MAGIC Consortium, MuTHER Consortium, Ripatti, S., Kaprio, J. & Lokki, M-L., 2012, In : PLoS Genetics. 8, 3, p. e1002607 23 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis

Inouye, M., Ripatti, S., Kettunen, J., Lyytikainen, L-P., Oksala, N., Laurila, P-P., Kangas, A. J., Soininen, P., Savolainen, M. J., Viikari, J., Kahonen, M., Perola, M., Salomaa, V., Raitakari, O., Lehtimaki, T., Taskinen, M-R., Jaervelin, M-R., Ala-Korpela, M., Palotie, A. & de Bakker, P. I. W., 1 Aug 2012, In : PLoS Genetics. 8, 8, p. e1002907

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Phylogeographic variation in recombination rates within a global clone of methicillin-resistant Staphylococcus aureus

Castillo-Ramirez, S., Corander, J., Marttinen, P., Aldeljawi, M., Hanage, W. P., Westh, H., Boye, K., Gulay, Z., Bentley, S. D., Parkhill, J., Holden, M. T. & Feil, E. J., 2012, In : Genome Biology. 13, 12, p. R126 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Voight, B. F., Peloso, G. M., Orho-Melander, M., Frikke-Schmidt, R., Barbalic, M., Jensen, M. K., Hindy, G., Holm, H., Ding, E. L., Johnson, T., Schunkert, H., Samani, N. J., Clarke, R., Hopewell, J. C., Thompson, J. F., Li, M., Thorleifsson, G., Newton-Cheh, C., Musunuru, K., Pirruccello, J. P. & 106 othersSaleheen, D., Chen, L., Stewart, A. F. R., Schillert, A., Thorsteinsdottir, U., Thorgeirsson, G., Anand, S., Engert, J. C., Morgan, T., Spertus, J., Stoll, M., Berger, K., Martinelli, N., Girelli, D., McKeown, P. P., Patterson, C. C., Epstein, S. E., Devaney, J., Burnett, M-S., Mooser, V., Ripatti, S., Surakka, I., Nieminen, M. S., Sinisalo, J-P., Lokki, M-L., Perola, M., Havulinna, A., de Faire, U., Gigante, B., Ingelsson, E., Zeller, T., Wild, P., de Bakker, P. I. W., Klungel, O. H., Maitland-van der Zee, A-H., Peters, B. J. M., de Boer, A., Grobbee, D. E., Kamphuisen, P. W., Deneer, V. H. M., Elbers, C. C., Onland-Moret, N. C., Hofker, M. H., Wijmenga, C., Verschuren, W. M. M., Boer, J. M. A., van der Schouw, Y. T., Rasheed, A., Frossard, P., Demissie, S., Willer, C., Do, R., Ordovas, J. M., Abecasis, G. R., Boehnke, M., Mohlke, K. L., Daly, M. J., Guiducci, C., Burtt, N. P., Surti, A., Gonzalez, E., Purcell, S., Gabriel, S., Marrugat, J., Peden, J., Erdmann, J., Diemert, P., Willenborg, C., Koenig, I. R., Fischer, M., Hengstenberg, C., Ziegler, A., Buysschaert, I., Lambrechts, D., Van de Werf, F., Fox, K. A., El Mokhtari, N. E., Rubin, D., Schrezenmeir, J., Schreiber, S., Schaefer, A., Danesh, J., Blankenberg, S., Roberts, R., McPherson, R., Watkins, H., Hall, A. S., Overvad, K., Rimm, E., Boerwinkle, E., Tybjaerg-Hansen, A., Cupples, L. A., Reilly, M. P., Melander, O., Mannucci, P. M., Ardissino, D., Siscovick, D., Elosua, R., Stefansson, K., O'Donnell, C. J., Salomaa, V., Rader, D. J., Palotie, L., Schwartz, S. M., Altshuler, D. & Kathiresan, S., 2012, In : Lancet. 380, 9841, p. 572-580 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Population structure in the Neisseria, and the biological significance of fuzzy species

Corander, J., Connor, T. R., O'Dwyer, C. A., Kroll, J. S. & Hanage, W. P., 2012, In : Journal of the Royal Society Interface. 9, 71, p. 1208-1215 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Population subdivision and the detection of recombination in non-typable Haemophilus influenzae

Connor, T. R., Corander, J. & Hanage, W. P., Dec 2012, In : Microbiology. 158, no. Pt 12 , p. 2958-2964 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Pubertal Timing and Growth Influences Cardiometabolic Risk Factors in Adult Males and Females

Widen, E., Silventoinen, K., Sovio, U., Ripatti, S., Cousminer, D. L., Hartikainen, A-L., Laitinen, J., Pouta, A., Kaprio, J., Jarvelin, M-R., Peltonen, L. & Palotie, A., 2012, In : Diabetes Care. 35, 4, p. 850-856 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Re-analysis of Bipolar Disorder and Schizophrenia Gene Expression Complements the Kraepelinian Dichotomy

Qian, K., Di Lieto, A., Corander, J., Auvinen, P. & Greco, D., 2012, Advances in Systems Biology. Goryanin, I. I. & Goryachev, A. B. (eds.). New York: Springer, Vol. 736. p. 563-577 15 p. (Advances in Experimental Medicine and Biology; vol. 736, no. 5).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Restricted Gene Flow among Hospital Subpopulations of Enterococcus faecium

Willems, R. J. L., Top, J., van Schaik, W., Leavis, H., Bonten, M., Siren, J., Hanage, W. P. & Corander, J., 2012, In : mBio. 3, 4, p. e00151-12 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Species distribution modeling with Gaussian processes: A case study with the youngest stages of sea spawning whitefish (Coregonus lavaretus L. s.l.) larvae

Vanhatalo, J., Veneranta, L. & Hudd, R., 2012, In : Ecological Modelling. 228, p. 49-58 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Statistical Approach to Quality Control of Large Thermodynamic Databases

Nyman, H., Talonen, T., Roine, A., Hupa, M. & Corander, J., Oct 2012, In : Metallurgical and Materials Transactions B - Process Metallurgy and Materials Processing Science. 43, 5, p. 1113-1118 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Support for involvement of glutamate decarboxylase 1 and neuropeptide y in anxiety susceptibility

Donner, J., Sipila, T., Ripatti, S., Kananen, L., Chen, X., Kendler, K. S., Lönnqvist, J., Pirkola, S., Hettema, J. M. & Hovatta, I., 2012, In : American journal of medical genetics. Part B, Neuropsychiatric genetics. 159B, 3, p. 316-327 12 p.

Research output: Contribution to journalArticleScientificpeer-review