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Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis

Weinert, L. A., Chaudhuri, R. R., Wang, J., Peters, S. E., Corander, J., Jombart, T., Baig, A., Howell, K. J., Vehkala, M., Valimaki, N., Harris, D., Tran Thi Bich Chieu, Nguyen Van Vinh Chau, Campbell, J., Schultsz, C., Parkhill, J., Bentley, S. D., Langford, P. R., Rycroft, A. N., Wren, B. W. & 7 others, Farrar, J., Baker, S., Ngo Thi Hoa, Holden, M. T. G., Tucker, A. W., Maskell, D. J. & BRaDP1T Consortium, Mar 2015, In : Nature Communications. 6, 9 p., 6740.

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Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

eQTLGen Consortium, Timmers, P. R. H. J., Kettunen, J., Perola, M. & Ripatti, S., 15 Jan 2019, In : eLife. 8, 40 p., 39856.

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Genomitiedon arkaluonteisuus on tiukassa elävä myytti

Palotie, A., Kaunisto, M., Kääriäinen, H., Perola, M., Pitkänen, K., Ripatti, S., Soini, S. & Widén, E., 2018, In : Suomen lääkärilehti. 73, 15, p. 916-917 2 p.

Research output: Contribution to journalArticleProfessional

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Geographical structure and differential natural selection among North European populations

McEvoy, B. P., Montgomery, G. W., McRae, A. F., Ripatti, S., Perola, M., Spector, T. D., Cherkas, L., Ahmadi, K. R., Boomsma, D., Willemsen, G., Hottenga, J. J., Pedersen, N. L., Magnusson, P. K. E., Kyvik, K. O., Christensen, K., Kaprio, J., Heikkilä, K., Palotie, A., Widen, E., Muilu, J. & 7 others, Syvänen, A-C., Liljedahl, U., Hardiman, O., Cronin, S., Peltonen, L., Martin, N. G. & Visscher, P. M., 2009, In : Genome Research. 19, 5, p. 804-814 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland

Kerminen, S., Martin, A. R., Koskela, J., Ruotsalainen, S. E., Havulinna, A. S., Surakka, I., Palotie, A., Perola, M., Salomaa, V., Daly, M. J., Ripatti, S. & Pirinen, M., 6 Jun 2019, In : American Journal of Human Genetics. 104, 6, p. 1169-1181 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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GPrank: an R package for detecting dynamic elements from genome-wide time series

Topa, H. & Honkela, A., 4 Oct 2018, In : BMC Bioinformatics. 19, 6 p., 367.

Research output: Contribution to journalArticleScientificpeer-review

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GPstuff: Bayesian Modeling with Gaussian Processes

Vanhatalo, J., Riihimäki, J., Hartikainen, J., Jylänki, P., Tolvanen, V. & Vehtari, A., Apr 2013, In : Journal of Machine Learning Research. 14, p. 1175-1179 5 p.

Research output: Contribution to journalArticleScientificpeer-review

GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment

Rietveld, C. A., Medland, S. E., Derringer, J., Yang, J., Esko, T., Martin, N. W., Westra, H-J., Shakhbazov, K., Abdellaoui, A., Agrawal, A., Albrecht, E., Alizadeh, B. Z., Amin, N., Bamard, J., Baumeister, S. E., Benke, K. S., Bielak, L. F., Boatman, J. A., Boyle, P. A., Davies, G. & 31 others, De Leeuw, C., Eklund, N., Evans, D. S., Ferhmann, R., Fischer, K., Gieger, C., Gjessing, H. K., Haegg, S., Harris, J. R., Hayward, C., Holzapfel, C., Ibrahim-Verbaas, C. A., Ingelsson, E., Jacobsson, B., Joshi, P. K., Jugessur, A., Kaakinen, M., Karjalainen, J., Lahti, J., Nuotio, M-L., Eriksson, J. G., Kaprio, J., Latvala, A., Palotie, A., Perola, M., Räikkönen, K., Ripatti, S., Sarin, A-P., Surakka, I., Widen, E. & LifeLines Cohort Study, 21 Jun 2013, In : Science. 340, 6139, p. 1467-1471 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Haplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland

Martin, A. R., Karczewski, K. J., Kerminen, S., Kurki, M. I., Sarin, A-P., Artomov, M., Eriksson, J. G., Esko, T., Genovese, G., Havulinna, A. S., Kaprio, J., Konradi, A., Korányi, L., Kostareva, A., Männikkö, M., Metspalu, A., Perola, M., Prasad, R. B., Raitakari, O., Rotar, O. & 7 others, Salomaa, V., Groop, L., Palotie, A., Neale, B. M., Ripatti, S., Pirinen, M. & Daly, M. J., 3 May 2018, In : American Journal of Human Genetics. 102, 5, p. 760-775 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

Spjuth, O., Krestyaninova, M., Hastings, J., Shen, H-Y., Heikkinen, J., Waldenberger, M., Langhammer, A., Ladenvall, C., Esko, T., Persson, M-A., Heggland, J., Dietrich, J., Ose, S., Gieger, C., Ried, J. S., Peters, A., Fortier, I., de Geus, E. J. C., Klovins, J., Zaharenko, L. & 16 others, Willemsen, G., Hottenga, J-J., Litton, J-E., Karvanen, J., Boomsma, D. I., Groop, L., Rung, J., Palmgren, J., Pedersen, N. L., McCarthy, M. I., van Duijn, C. M., Hveem, K., Metspalu, A., Ripatti, S., Prokopenko, I. & Harris, J. R., Apr 2016, In : European Journal of Human Genetics. 24, 4, p. 521-528 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Have I Seen You Before? Principles of Bayesian Predictive Classification Revisited

Corander, J., Cui, Y., Koski, T. & Sirén, J., 2013, In : Statistics and Computing. 23, 1, p. 59-73 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Healthcare costs and outcomes in adult patients with juvenile idiopathic arthritis: a population-based study

Mars, N. J., Kerola, A. M., Kauppi, M. J., Pirinen, M., Elonheimo, O. & Sokka-Isler, T., 4 Mar 2019, In : Scandinavian Journal of Rheumatology. 48, 2, p. 114-120 7 p.

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Hierarchical and spatially explicit clustering of DNA sequences with BAPS software

Cheng, L., Connor, T. R., Siren, J., Aanensen, D. M. & Corander, J., 13 Feb 2013, In : Molecular Biology and Evolution. 30, 5, p. 1224-1228 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Hierarchical Bayesian Model for Rare Variant Association Analysis Integrating Genotype Uncertainty in Human Sequence Data

He, L., Pitkaniemi, J., Sarin, A-P., Salomaa, V., Sillanpaa, M. J. & Ripatti, S., Feb 2015, In : Genetic Epidemiology. 39, 2, p. 89-100 12 p.

Research output: Contribution to journalArticleScientificpeer-review

High degree of cryptic population differentiation in the Baltic Sea herring Clupea harengus

Corander, J., Majander, K. K., Cheng, L. & Merila, J., Jun 2013, In : Molecular Ecology. 22, 11, p. 2931-2940 10 p.

Research output: Contribution to journalArticleScientificpeer-review

High-dimensional structure learning of binary pairwise Markov networks: A comparative numerical study

Pensar, J., Xu, Y., Puranen, S., Pesonen, M., Kabashima, Y. & Corander, J., Jan 2020, In : Computational Statistics & Data Analysis. 141, p. 62-76 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms

Kurki, M. I., Gaal, E. I., Kettunen, J., Lappalainen, T., Menelaou, A., Anttila, V., van't Hof, F. N. G., von und zu Fraunberg, M., Helisalmi, S., Hiltunen, M., Lehto, H., Laakso, A., Kivisaari, R., Koivisto, T., Ronkainen, A., Rinne, J., Kiemeney, L. A. L., Vermeulen, S. H., Kaunisto, M. A., Eriksson, J. G. & 15 others, Aromaa, A., Perola, M., Lehtimaki, T., Raitakari, O. T., Salomaa, V., Gunel, M., Dermitzakis, E. T., Ruigrok, Y. M., Rinkel, G. J. E., Niemela, M., Hernesniemi, J., Ripatti, S., de Bakker, P. I. W., Palotie, A. & Jaaskelainen, J. E., Jan 2014, In : PLoS Genetics. 10, 1, 12 p., 1004134.

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Historical Zoonoses and Other Changes in Host Tropism of Staphylococcus aureus, Identified by Phylogenetic Analysis of a Population Dataset

Shepheard, M. A., Fleming, V. M., Connor, T. R., Corander, J., Feil, E. J., Fraser, C. & Hanage, W. P., 7 May 2013, In : PLoS One. 8, 5, 9 p., e62369.

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Hostility in adolescents and adults: a genome-wide association study of the Young Finns

Merjonen, P., Keltikangas-Järvinen, L., Jokela, M., Seppälä, I., Lyytikäinen, L-P., Pulkki-Råback, L., Kivimäki, M., Elovainio, M., Kettunen, J., Ripatti, S., Kähönen, M., Viikari, J., Palotie, A., Peltonen, L., Raitakari, O. T. & Lehtimäki, T., 2011, In : Translational Psychiatry. 1, 7 p., 11.

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How could use of genetic markers prevent coronary heart disease events?

Ripatti, S. & Salomaa, V., Nov 2013, In : Personalized Medicine. 10, 8, p. 769-771 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Allen, H. L., Estrada, K., Lettre, G., Berndt, S. I., Weedon, M. N., Rivadeneira, F., Willer, C. J., Jackson, A. U., Vedantam, S., Raychaudhuri, S., Ferreira, T., Wood, A. R., Weyant, R. J., Segre, A. V., Speliotes, E. K., Wheeler, E., Soranzo, N., Park, J-H., Yang, J., Gudbjartsson, D. & 271 others, Heard-Costa, N. L., Randall, J. C., Qi, L., Smith, A. V., Maegi, R., Pastinen, T., Liang, L., Heid, I. M., Luan, J., Thorleifsson, G., Winkler, T. W., Goddard, M. E., Lo, K. S., Palmer, C., Workalemahu, T., Aulchenko, Y. S., Johansson, A., Zillikens, M. C., Feitosa, M. F., Esko, T., Johnson, T., Ketkar, S., Kraft, P., Mangino, M., Prokopenko, I., Absher, D., Albrecht, E., Ernst, F., Glazer, N. L., Hayward, C., Hottenga, J-J., Jacobs, K. B., Knowles, J. W., Kutalik, Z., Monda, K. L., Polasek, O., Preuss, M., Rayner, N. W., Robertson, N. R., Steinthorsdottir, V., Tyrer, J. P., Voight, B. F., Wiklund, F., Xu, J., Zhao, J. H., Nyholt, D. R., Pellikka, N., Perola, M., Perry, J. R. B., Surakka, I., Tammesoo, M-L., Altmaier, E. L., Amin, N., Aspelund, T., Bhangale, T., Boucher, G., Chasman, D. I., Chen, C., Coin, L., Cooper, M. N., Dixon, A. L., Gibson, Q., Grundberg, E., Hao, K., Junttila, M. J., Kaplan, L. M., Kettunen, J., Koenig, I. R., Kwan, T., Lawrence, R. W., Levinson, D. F., Lorentzon, M., McKnight, B., Morris, A. P., Mueller, M., Ngwa, J. S., Purcell, S., Rafelt, S., Salem, R. M., Salvi, E., Sanna, S., Shi, J., Sovio, U., Thompson, J. R., Turchin, M. C., Vandenput, L., Verlaan, D. J., Vitart, V., White, C. C., Ziegler, A., Almgren, P., Balmforth, A. J., Campbell, H., Citterio, L., De Grandi, A., Dominiczak, A., Duan, J., Elliott, P., Elosua, R., Eriksson, J. G., Freimer, N. B., Geus, E. J. C., Glorioso, N., Haiqing, S., Hartikainen, A-L., Havulinna, A. S., Hicks, A. A., Hui, J., Igl, W., Illig, T., Jula, A., Kajantie, E., Kilpelaeinen, T. O., Koiranen, M., Kolcic, I., Koskinen, S., Kovacs, P., Laitinen, J., Liu, J., Lokki, M-L., Marusic, A., Maschio, A., Meitinger, T., Mulas, A., Pare, G., Parker, A. N., Peden, J. F., Petersmann, A., Pichler, I., Pietiläinen, K. H., Pouta, A., Riddertrale, M., Rotter, J. I., Sambrook, J. G., Sanders, A. R., Schmidt, C. O., Sinisalo, J., Smit, J. H., Stringham, H. M., Walters, G. B., Widen, E., Wild, S. H., Willemsen, G., Zagato, L., Zgaga, L., Zitting, P., Alavere, H., Farrall, M., McArdle, W. L., Nelis, M., Peters, M. J., Ripatti, S., vVan Meurs, J. B. J., Aben, K. K., Ardlie, K. G., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Collins, F. S., Cusi, D., den Heijer, M., Eiriksdottir, G., Gejman, P. V., Hall, A. S., Hamsten, A., Huikuri, H. V., Iribarren, C., Kahonen, M., Kaprio, J., Kathiresan, S., Kiemeney, L., Kocher, T., Launer, L. J., Lehtimaki, T., Melander, O., Mosley, T. H., Musk, A. W., Nieminen, M. S., O'Donnell, C. J., Ohlsson, C., Oostra, B., Palmer, L. J., Raitakari, O., Ridker, P. M., Rioux, J. D., Rissanen, A., Rivolta, C., Schunkert, H., Shuldiner, A. R., Siscovick, D. S., Stumvoll, M., Toenjes, A., Tuomilehto, J., van Ommen, G-J., Viikari, J., Heath, A. C., Martin, N. G., Montgomery, G. W., Province, M. A., Kayser, M., Arnold, A. M., Atwood, L. D., Boerwinkle, E., Chanock, S. J., Deloukas, P., Gieger, C., Gronberg, H., Hall, P., Hattersley, A. T., Hengstenberg, C., Hoffman, W., Lathrop, G. M., Salomaa, V., Schreiber, S., Uda, M., Waterworth, D., Wright, A. F., Assimes, T. L., Barroso, I., Hofman, A., Mohlke, K. L., Boomsma, D. I., Caulfield, M. J., Cupples, L. A., Erdmann, J., Fox, C. S., Gudnason, V., Gyllensten, U., Harris, T. B., Hayes, R. B., Jarvelin, M-R., Mooser, V., Munroe, P. B., Ouwehand, W. H., Penninx, B. W., Pramstaller, P. P., Quertermous, T., Rudan, I., Samani, N. J., Spector, T. D., Voelzke, H., Watkins, H., Wilson, J. F., Groop, L. C., Haritunians, T., Hu, F. B., Kaplan, R. C., Metspalu, A., North, K. E., Schlessinger, D., Wareham, N. J., Hunter, D. J., O'Connell, J. R., Strachan, D. P., Schadt, H. -E., Thorsteinsdottir, U., Peltonen, L., Uitterlinden, A. G., Visscher, P. M., Chatterjee, N., Loos, R. J. F., Boehnke, M., McCarthy, M. I., Ingelsson, E., Lindgren, C. M., Abecasis, G. R., Stefansson, K., Frayling, T. M., Hirschhorn, J. N. & Procardis Consortium, 2010, In : Nature. 467, 7317 , p. 832-838 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Hydrographic responses to regional covariates across the Kara Sea

Mäkinen, J. A-E. & Vanhatalo, J. P., Dec 2016, In : Journal of Geophysical Research : Oceans. 121, 12, p. 8872-8887 16 p.

Research output: Contribution to journalArticleScientificpeer-review

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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Tsoi, L. C., Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, J. E., Kang, H. M., Allen, M. H., McManus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Stahle, M., Burden, A. D., Smith, C. H., Cork, M. J. & 179 others, Estivill, X., Bowcock, A. M., Krueger, G. G., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, F. O., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, R. D., Vukcevic, D., Spencer, C. C. A., Deloukas, P., Mrowietz, U., Schreiber, S., Weidinger, S., Koks, S., Kingo, K., Esko, T., Metspalu, A., Lim, H. W., Voorhees, J. J., Weichenthal, M., Wichmann, H. E., Chandran, V., Rosen, C. F., Rahman, P., Gladman, D. D., Griffiths, C. E. M., Reis, A., Kere, J., Nair, R. P., Franke, A., Barker, J. N. W. N., Abecasis, G. R., Elder, J. T., Trembath, R. C., Duffin, K. C., Helms, C., Goldgar, D., Li, Y., Paschall, J., Malloy, M. J., Pullinger, C. R., Kane, J. P., Gardner, J., Perlmutter, A., Miner, A., Feng, B. J., Hiremagalore, R., Ike, R. W., Christophers, E., Henseler, T., Ruether, A., Schrodi, S. J., Prahalad, S., Guthery, S. L., Fischer, J., Liao, W., Kwok, P., Menter, A., Lathrop, G. M., Wise, C., Begovich, A. B., Onoufriadis, A., Weale, M. E., Hofer, A., Salmhofer, W., Wolf, P., Kainu, K., Saarialho-Kere, U., Suomela, S., Badorf, P., Hueffmeier, U., Kurrat, W., Kuester, W., Lascorz, J., Moessner, R., Schuermeier-Horst, F., Staender, M., Traupe, H., Bergboer, J. G. M., den Heijer, M., van de Kerkhof, P. C., Zeeuwen, P. L. J. M., Barnes, L., Campbell, L. E., Cusack, C., Coleman, C., Conroy, J., Ennis, S., Fitzgerald, O., Gallagher, P., Irvine, A. D., Kirby, B., Markham, T., McLean, W. H. I., McPartlin, J., Rogers, S. F., Ryan, A. W., Zawirska, A., Giardina, E., Lepre, T., Perricone, C., Martin-Ezquerra, G., Pujol, R. M., Riveira-Munoz, E., Inerot, A., Naluai, A. T., Mallbris, L., Wolk, K., Leman, J., Barton, A., Warren, R. B., Young, H. S., Ricano-Ponce, I., Trynka, G., Pellett, F. J., Henschel, A., Aurand, M., Bebo, B., Gieger, C., Illig, T., Moebus, S., Joeckel, K-H., Erbe, R., Donnelly, P., Palotie, L., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Craddock, N., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., McCarthy, M. I., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Samani, N., Viswanathan, A. C., Wood, N. W., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Su, Z., Hunt, S. E., Gwilliam, R., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Perez, M. L., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P. & Wellcome Trust Case Control Consor, Collaborative Assoc Study Psoriasi, Genetic Anal Psoriasis Consortium, Psoriasis Assoc Genetics Extension, Dec 2012, In : Nature Genetics. 44, 12, p. 1341-1348 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification of a Novel Genomic Island Associated with vanD-Type Vancomycin Resistance in Six Dutch Vancomycin-Resistant Enterococcus faecium Isolates

Top, J., Sinnige, J. C., Brouwer, E. C., Werner, G., Corander, J., Severin, J. A., Jansen, R., Bathoorn, E., Bonten, M. J. M., Rossen, J. W. A. & Willems, R. J. L., Mar 2018, In : Antimicrobial Agents and Chemotherapy. 62, 3, 7 p., e01793-17.

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Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution

von Mentzer, A., Connor, T. R., Wieler, L. H., Semmler, T., Iguchi, A., Thomson, N. R., Rasko, D. A., Joffre, E., Corander, J., Pickard, D., Wiklund, G., Svennerholm, A-M., Sjoling, A. & Dougan, G., Dec 2014, In : Nature Genetics. 46, 12, p. 1321-1326 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 33 others, Lu, Y., Zhang, W., Imran, A., Abbas, S., Majeed, F., Trindade, K., Qamar, N., Mallick, N. H., Yaqoob, Z., Saghir, T., Rizvi, S. N. H., Memon, A., Rasheed, S. Z., Memon, F-R., Mehmood, K., Ahmed, N., Qureshi, I. H., Tanveer-us-Salam, Iqbal, W., Malik, U., Mehra, N., Kuo, J. Z., Sheu, W. H-H., Guo, X., Hsiung, C. A., Juang, J-M. J., Taylor, K. D., Hung, Y-J., Lee, W-J., Ripatti, S., CHD Exome Consortium, EPIC-CVD Consortium & EPIC-Interact Consortium, Oct 2017, In : Nature Genetics. 49, 10, p. 1450-+ 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification of seven loci affecting mean telomere length and their association with disease

Codd, V., Nelson, C. P., Albrecht, E., Mangino, M., Deelen, J., Buxton, J. L., Hottenga, J. J., Fischer, K., Esko, T., Surakka, I., Broer, L., Nyholt, D. R., Leach, I. M., Salo, P., Hagg, S., Matthews, M. K., Palmen, J., Norata, G. D., O'Reilly, P. F., Saleheen, D. & 80 others, Amin, N., Balmforth, A. J., Beekman, M., de Boer, R. A., Bohringer, S., Braund, P. S., Burton, P. R., de Craen, A. J. M., Denniff, M., Dong, Y., Douroudis, K., Dubinina, E., Eriksson, J. G., Garlaschelli, K., Guo, D., Hartikainen, A-L., Henders, A. K., Houwing-Duistermaat, J. J., Kananen, L., Karssen, L. C., Kettunen, J., Klopp, N., Lagou, V., van Leeuwen, E. M., Madden, P. A., Maegi, R., Magnusson, P. K. E., Mannisto, S., McCarthy, M. I., Medland, S. E., Mihailov, E., Montgomery, G. W., Oostra, B. A., Palotie, A., Peters, A., Pollard, H., Pouta, A., Prokopenko, I., Ripatti, S., Salomaa, V., Suchiman, H. E. D., Valdes, A. M., Verweij, N., Vinuela, A., Wang, X., Wichmann, H-E., Widen, E., Willemsen, G., Wright, M. J., Xia, K., Xiao, X., van Veldhuisen, D. J., Catapano, A. L., Tobin, M. D., Hall, A. S., Blakemore, A. I. F., van Gilst, W. H., Zhu, H., Erdmann, J., Reilly, M. P., Kathiresan, S., Schunkert, H., Talmud, P. J., Pedersen, N. L., Perola, M., Ouwehand, W., Kaprio, J., Martin, N. G., van Duijn, C. M., Hovatta, I., Gieger, C., Metspalu, A., Boomsma, D. I., Jarvelin, M-R., Slagboom, P. E., Thompson, J. R., Spector, T. D., van der Harst, P., Samani, N. J. & CARDIoGRAM Consortium, Apr 2013, In : Nature Genetics. 45, 4, p. 422-427 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Identifying currents in the gene pool for bacterial populations using an integrative approach

Tang, J., Hanage, W., Fraser, C. & Corander, J., 2009, In : PLoS Computational Biology. 5, 8, p. e1000455 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Identifying differentially expressed transcripts from RNA-seq data with biological variation

Glaus, P., Honkela, A. & Rattray, M., 2012, In : Bioinformatics. 28, 13, p. 1721-1728 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

eQTLGen Consortium, 2018, In : Nature Communications. 9, 1

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Identifying Multiple Potential Metabolic Cycles in Time-Series from Biolog Experiments

Shubin, M., Schaufler, K., Tedin, K., Vehkala, M. & Corander, J., 27 Sep 2016, In : PLoS One. 11, 9, 14 p., 0162276.

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Identifying targets of multiple co-regulating transcription factors from expression time-series by Bayesian model comparison

Titsias, M. K., Honkela, A., Lawrence, N. D. & Rattray, M., 30 May 2012, In : BMC Systems Biology. 6, 21 p., 53.

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Impact of Common Variation in Bone-Related Genes on Type 2 Diabetes and Related Traits

Billings, L. K., Hsu, Y-H., Ackerman, R. J., Dupuis, J., Voight, B. F., Rasmussen-Torvik, L. J., Hercberg, S., Lathrop, M., Barnes, D., Langenberg, C., Hui, J., Fu, M., Bouatia-Naji, N., Lecoeur, C., An, P., Magnusson, P. K., Surakka, I. L., Ripatti, S., Christiansen, L., Dalgard, C. & 21 others, Folkersen, L., Grundberg, E., Eriksson, P., Kaprio, J., Kyvik, K. O., Pedersen, N. L., Borecki, I. B., Province, M. A., Balkau, B., Froguel, P., Shuldiner, A. R., Palmer, L. J., Wareham, N., Meneton, P., Johnson, T., Pankow, J. S., Karasik, D., Meigs, J. B., Kiel, D. P., Florez, J. C. & ASCOT Investigators, DIAGRAM Consortium, MuTHER Consortium, MAGIC Investigators, GEFOS Consortium, 2012, In : Diabetes. 61, 8, p. 2176-2186 11 p.

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Impacts of eutrophication and oil spills on the Gulf of Finland herring stock

Rahikainen, M. K., Hoviniemi, K-M., Mäntyniemi, S. H. P., Vanhatalo, J. P., Helle, S. I., Lehtiniemi, M., Pönni, J. & Kuikka, O. S., 2017, In : Canadian Journal of Fisheries and Aquatic Sciences. 74, 8, p. 1218-1232 15 p.

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Impacts of oil spills on Arctic marine ecosystems: A quantitative and probabilistic risk assessment perspective

Helle, I., Mäkinen, J. A-E., Nevalainen, M. K., Afenyo, M. & Vanhatalo, J., 18 Feb 2020, In : Environmental Science & Technology. 54, 4, p. 2112-2121 10 p.

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Implant survival of constrained acetabular device in primary total hip arthroplasty based on data from the Finnish Arthroplasty Register

Karvonen, M., Laaksonen, I., Pulkkinen, P., Eskelinen, A., Haapakoski, J., Puhto, A-P., Kettunen, J., Manninen, M. & Mäkelä, K. T., Jan 2020, In : Journal of Arthroplasty. 35, 1, p. 219-223 5 p.

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Implications of a Circulating Vaccine-Derived Poliovirus in Nigeria.

Jenkins, H. E., Aylward, R. B., Gasasira, A., Donnelly, C. A., Mwanza, M., Corander, J., Garnier, S., Chauvin, C., Abanida, E., Pate, M. A., Adu, F., Baba, M. & Grassly, N. C., 2010, In : New England Journal of Medicine. 362, p. 2360-2369 10 p.

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Improved Statistical Modeling of Tumor Growth and Treatment Effect in Preclinical Animal Studies with Highly Heterogeneous Responses In Vivo

Laajala, T. D., Corander, J., Saarinen, N. M., Makela, K., Savolainen, S., Suominen, M. I., Alhoniemi, E., Makela, S., Poutanen, M. & Aittokallio, T., 2012, In : Clinical Cancer Research. 18, 16, p. 4385-4396 12 p.

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Improving Illumina assemblies with Hi-C and long reads: An example with the North African dromedary

Elbers, J. P., Rogers, M. F., Perelman, P. L., Proskuryakova, A. A., Serdyukova, N. A., Johnson, W. E., Horin, P., Corander, J., Murphy, D. & Burger, P. A., Jul 2019, In : Molecular Ecology Resources. 19, 4, p. 1015-1026 12 p.

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Including known covariates can reduce power to detect genetic effects in case-control studies

Pirinen, M., Donnelly, P. & Spencer, C. C. A., Aug 2012, In : Nature Genetics. 44, 8, p. 848-851 4 p.

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In defence of model-based inference in phylogeography REPLY

Beaumont, M. A., Nielsen, R., Robert, C., Hey, J., Gaggiotti, O., Knowles, L., Estoup, A., Panchal, M., Corander, J., Hickerson, M., Sisson, S. A., Fagundes, N., Chikhi, L., Beerli, P., Vitalis, R., Cornuet, J-M., Huelsenbeck, J., Foll, M., Yang, Z., Rousset, F. & 2 others, Balding, D. & Excoffier, L., 2010, In : Molecular Ecology. 19, p. 436-446 11 p.

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Index-based approach for estimating vulnerability of Arctic biota to oil spills

Nevalainen, M. K., Vanhatalo, J. & Helle, I., 18 Jun 2019, In : Ecosphere. 10, 6, 24 p., 02766.

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Inference of RNA Polymerase II Transcription Dynamics from Chromatin Immunoprecipitation Time Course Data

wa Maina, C., Honkela, A., Matarese, F., Grote, K., Stunnenberg, H. G., Reid, G., Lawrence, N. D. & Rattray, M., May 2014, In : PLoS Computational Biology. 10, 5, 17 p., e1003598.

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Inference on Population Histories by Approximating Infinite Alleles Diffusion

Siren, J., Hanage, W. P. & Corander, J., Feb 2013, In : Molecular Biology and Evolution. 30, 2, p. 457-468 12 p.

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Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

Int IBD Genetics Consortium, NIDDK IBD Genetics Consortium, T2D-Genes Consortium, Rivas, M. A., Koskela, J., Pirinen, M., Kurki, M., Saavalainen, P., Farkkila, M., Kontula, K., Palotie, A. & Daly, M. J., May 2018, In : PLoS Genetics. 14, 5, 25 p., 1007329.

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Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis

Kachroo, P., Eraso, J. M., Beres, S. B., Olsen, R. J., Zhu, L., Nasser, W., Bernard, P. E., Cantu, C. C., Saavedra, M. O., Arredondo, M. J., Strope, B., Do, H., Kumaraswami, M., Vuopio, J., Gröndahl-Yli-Hannuksela, K., Kristinsson, K. G., Gottfredsson, M., Pesonen, M., Pensar, J., Davenport, E. R. & 11 others, Clark, A. G., Corander, J., Caugant, D. A., Gaini, S., Magnussen, M. D., Kubiak, S. L., Nguyen, H. A. T., Long, S. W., Porter, A. R., DeLeo, F. R. & Musser, J. M., Mar 2019, In : Nature Genetics. 51, 3, p. 548-563 15 p.

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Integrating experimental and distribution data to predict future species patterns

Kotta, J., Vanhatalo, J. P., Jänes, H., Orav-Kotta, H., Rugiu, L., Jormalainen, V., Bobsien, I., Viitasalo, M., Virtanen, E., Nyström Sandman, A., Isaeus, M., Leidenberger, S., Jonsson, P. R. & Johannesson, K., 12 Feb 2019, In : Scientific Reports. 9, 14 p., 1821.

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Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis

Skwark, M. J., Croucher, N. J., Puranen, S., Chewapreecha, C., Pesonen, M., Xu, Y. Y., Turner, P., Harris, S. R., Beres, S. B., Musser, J. M., Parkhill, J., Bentley, S. D., Aurell, E. & Corander, J., Feb 2017, In : PLoS Genetics. 13, 2, 24 p., 1006508.

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Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

Evans, D. M., Spencer, C. C. A., Pointon, J. J., Su, Z., Harvey, D., Kochan, G., Opperman, U., Dilthey, A., Pirinen, M., Stone, M. A., Appleton, L., Moutsianis, L., Leslie, S., Wordsworth, T., Kenna, T. J., Karaderi, T., Thomas, G. P., Ward, M. M., Weisman, M. H., Farrar, C. & 33 others, Bradbury, L. A., Danoy, P., Inman, R. D., Maksymowych, W., Gladman, D., Rahman, P., Morgan, A., Marzo-Ortega, H., Bowness, P., Gaffney, K., Gaston, J. S. H., Smith, M., Bruges-Armas, J., Couto, A-R., Sorrentino, R., Paladini, F., Ferreira, M. A., Xu, H., Liu, Y., Jiang, L., Lopez-Larrea, C., Diaz-Pena, R., Lopez-Vazquez, A., Zayats, T., Band, G., Bellenguez, C., Blackburn, H., Blackwell, J. M., Palotie, L., Rautanen, A., Australo-Anglo-Amer Spondyloarthri, Wellcome Trust Case Control Consor & Spondyloarthrit Res Consortium Can, Aug 2011, In : Nature Genetics. 43, 8, p. 761-767 7 p.

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Inverse finite-size scaling for high-dimensional significance analysis

Xu, Y., Puranen, S., Corander, J. & Kabashima, Y., 6 Jun 2018, In : Physical Review E. 97, 6, 9 p., 062112.

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