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The landscape of genomic imprinting across diverse adult human tissues

Baran, Y., Subramaniam, M., Biton, A., Tukiainen, T., Tsang, E. K., Rivas, M. A., Pirinen, M., Gutierrez-Arcelus, M., Smith, K. S., Kukurba, K. R., Zhang, R., Eng, C., Torgerson, D. G., Urbanek, C., Li, J. B., Rodriguez-Santana, J. R., Burchard, E. G., Seibold, M. A., MacArthur, D. G., Montgomery, S. B. & 3 others, Zaitlen, N. A., Lappalainen, T. & GTEx Consortium, Jul 2015, In : Genome Research. 25, 7, p. 927-936 10 p.

Research output: Contribution to journalArticleScientificpeer-review

The learning for mixtures of multicausal interaction networks

Westerlind, H., Jääskinen, V., Corander, J., Hillert, J. & Koski, T., 2014, (Submitted) In : Statistics in Medicine.

Research output: Contribution to journalArticleScientificpeer-review

The Molecular Genetic Architecture of Self-Employment

van der Loos, M. J. H. M., Rietveld, C. A., Eklund, N., Koellinger, P. D., Rivadeneira, F., Abecasis, G. R., Ankra-Badu, G. A., Baumeister, S. E., Benjamin, D. J., Biffar, R., Blankenberg, S., Boomsma, D. I., Cesarini, D., Cucca, F., de Geus, E. J. C., Dedoussis, G., Deloukas, P., Dimitriou, M., Eiriksdottir, G., Eriksson, J. & 48 others, Gieger, C., Gudnason, V., Hoehne, B., Holle, R., Hottenga, J-J., Isaacs, A., Jarvelin, M-R., Johannesson, M., Kaakinen, M., Kahonen, M., Kanoni, S., Laaksonen, M. A., Lahti, J., Launer, L. J., Lehtimaki, T., Loitfelder, M., Magnusson, P. K. E., Naitza, S., Oostra, B. A., Perola, M., Petrovic, K., Quaye, L., Raitakari, O., Ripatti, S., Scheet, P., Schlessinger, D., Schmidt, C. O., Schmidt, H., Schmidt, R., Senft, A., Smith, A. V., Spector, T. D., Surakka, I., Svento, R., Terracciano, A., Tikkanen, E., van Duijn, C. M., Viikari, J., Voelzke, H., Wichmann, H. -E., Wild, P. S., Willems, S. M., Willemsen, G., van Rooij, F. J. A., Groenen, P. J. F., Uitterlinden, A. G., Hofman, A. & Thurik, A. R., 4 Apr 2013, In : PLoS One. 8, 4, p. Article Number: e60542 15 p.

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The rocky road to personalized medicine: computational and statistical challenges

Corander, J., Aittokallio, T., Ripatti, S. & Kaski, S., 2012, In : Personalized Medicine. 9, 2, p. 109-114 6 p.

Research output: Contribution to journalArticleScientific

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

Fall, T., Hagg, S., Maegi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A-P., Thorleifsson, G., Ladenvall, C., Kals, M., Kuningas, M., Draisma, H. H. M., Ried, J. S., van Zuydam, N. R., Huikari, V., Mangino, M., Sonestedt, E., Benyamin, B., Nelson, C. P., Rivera, N. V. & 31 others, Kristiansson, K., Shen, H., Havulinna, A. S., Dehghan, A., Donnelly, L. A., Kaakinen, M., Nuotio, M-L., Robertson, N., de Bruijn, R. F. A. G., Ikram, M. A., Amin, N., Balmforth, A. J., Braund, P. S., Doney, A. S. F., Doering, A., Elliott, P., Esko, T., Franco, O. H., Gretarsdottir, S., Hartikainen, A-L., Heikkilä, K. V., Herzig, K-H., Holm, H., Hottenga, J. J., Hypponen, E., Kettunen, J., Kaprio, J., Tuomi, T., Groop, L., Ripatti, S. & ENGAGE Consortium, Jun 2013, In : PLoS Medicine. 10, 6, p. e1001474 15 p.

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The role of local partial independence in learning of Bayesian networks

Pensar, J., Nyman, H., Lintusaari, J. & Corander, J., Feb 2016, In : International Journal of Approximate Reasoning. 69, p. 91-105 15 p.

Research output: Contribution to journalArticleScientificpeer-review

The transcriptional landscape of age in human peripheral blood

Peters, M. J., Joehanes, R., Pilling, L. C., Schurmann, C., Conneely, K. N., Powell, J., Reinmaa, E., Sutphin, G. L., Zhernakova, A., Schramm, K., Wilson, Y. A., Kobes, S., Tukiainen, T., Ramos, Y. F., Goering, H. H. H., Fornage, M., Liu, Y., Gharib, S. A., Stranger, B. E., De Jager, P. L. & 31 others, Aviv, A., Levy, D., Murabito, J. M., Munson, P. J., Huan, T., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., van Rooij, J., Stolk, L., Broer, L., Verbiest, M. M. P. J., Jhamai, M., Arp, P., Metspalu, A., Tserel, L., Milani, L., Samani, N. J., Peterson, P., Kasela, S., Codd, V., Peters, A., Ward-Caviness, C. K., Herder, C., Waldenberger, M., Roden, M., Hovatta, I., Perola, M., Ripatti, S., Kettunen, J. & NABEC UKBEC Consortium, Oct 2015, In : Nature Communications. 6, 14 p., 8570.

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The Value of Reducing Eutrophication in European Marine Areas - A Bayesian Meta-analysis

Ahtiainen, H. & Vanhatalo, J., 2012, In : Ecological Economics. 83, p. 1-10 10 p.

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tigre: Transcription factor inference through gaussian process reconstruction of expression for bioconductor

Honkela, A., Gao, P., Ropponen, J., Rattray, M. & Lawrence, N. D., 2011, In : Bioinformatics. 27, 7, p. 1026-1027 2 p.

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Toward Integrative Management Advice of Water Quality, Oil Spills, and Fishery in the Gulf of Finland: A Bayesian Approach

Rahikainen, M., Helle, I., Haapasaari, P., Oinonen, S., Kuikka, S., Vanhatalo, J., Mantyniemi, S. & Hoviniemi, K-M., Feb 2014, In : Ambio. 43, 1, p. 115-123 9 p.

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Towards a Molecular Systems Model of Coronary Artery Disease

Abraham, G., Bhalala, O. G., de Bakker, P. I. W., Ripatti, S. & Inouye, M., Jun 2014, In : Current cardiology reports.. 16, 6, 10 p., 488.

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Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Res Team & Räikkönen, K., Dec 2018, In : Nature Neuroscience. 21, 12, p. 1656-+ 16 p.

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Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 44 others, Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samue, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stancakova, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Gjesing, A. P., Kontto, J., Perola, M., Shaw-Hawkins, S., Havulinna, A. S., Kajantie, E., Tuomi, T., Groop, L., Palotie, A., Ripatti, S., CHARGE Heart Failure Consortiumm, EchoGen Consortiumm, Metastroke Consortiumm, Giant Consortiumm, EPIC-InterAct Consortium, Lifelines Cohort Study, Wellcome Trust Case Control Consor, Understanding Soc Sci Grp, EPIC-CVD Consortium, CHARGE Exome Chip Blood Pressure C, T2D-GENES Consortium, GoT2DGenes Consortium, ExomeBP Consortium & CHD Exome Consortium, Oct 2016, In : Nature Genetics. 48, 10, p. 1151-1161 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Transcriptome Analysis Reveals Signature of Adaptation to Landscape Fragmentation

Somervuo, P., Kvist, J., Ikonen, S., Auvinen, P., Paulin, L., Koskinen, P., Holm, L., Taipale, M., Duplouy, A., Ruokolainen, A., Saarnio, S., Siren, J., Kohonen, J., Corander, J., Frilander, M. J., Ahola, V. & Hanski, I., 2 Jul 2014, In : PLoS One. 9, 7, 12 p., 101467.

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Transcriptome Remodeling Contributes to Epidemic Disease Caused by the Human Pathogen Streptococcus pyogenes

Beres, S. B., Kachroo, P., Nasser, W., Olsen, R. J., Zhu, L., Flores, A. R., de la Riva, I., Paez-Mayorga, J., Jimenez, F. E., Cantu, C., Vuopio, J., Jalava, J., Kristinsson, K. G., Gottfredsson, M., Corander, J., Fittipaldi, N., Di Luca, M. C., Petrelli, D., Vitali, L. A., Raiford, A. & 2 others, Jenkins, L. & Musser, J. M., 2016, In : mBio. 7, 3, 14 p., ARTN 00403-16.

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Transfer of noncoding DNA drives regulatory rewiring in bacteria

Oren, Y., Smith, M. B., Johns, N. I., Zeevi, M. K., Biran, D., Ron, E. Z., Corander, J., Wang, H. H., Alm, E. J. & Pupko, T., 11 Nov 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 45, p. 16112-16117 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Two-phase importance sampling for inference about transmission trees

Numminen, S. E., Chewapreecha, C., Siren, J., Turner, C., Turner, P., Bentley, S. & Corander, J., 2014, In : Proceedings of the Royal Society B. Biological Sciences. 281, 1794, 10 p., 20141324.

Research output: Contribution to journalArticleScientificpeer-review

Understanding pneumococcal serotype 1 biology through population genomic analysis

Chaguza, C., Cornick, J. E., Harris, S. R., Andam, C. P., Bricio-Moreno, L., Yang, M., Yalcin, F., Ousmane, S., Govindpersad, S., Senghore, M., Ebruke, C., Du Plessis, M., Kiran, A. M., Pluschke, G., Sigauque, B., McGee, L., Klugman, K. P., Turner, P., Corander, J., Parkhill, J. & 10 others, Collard, J-M., Antonio, M., von Gottberg, A., Heyderman, R. S., French, N., Kadioglu, A., Hanage, W. P., Everett, D. B., Bentley, S. D. & PAGe Consortium, 8 Nov 2016, In : BMC Infectious Diseases. 16, 14 p., 649.

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Use of Genome-Wide Expression Data to Mine the "Gray Zone" of GWA Studies Leads to Novel Candidate Obesity Genes

Naukkarinen, J., Surakka, I., Pietiläinen, K. H., Rissanen, A., Salomaa, V., Ripatti, S., Yki-Järvinen, H., van Duijn, C. M., Wichmann, H. -E., Kaprio, J., Taskinen, M-R., Peltonen, L. & ENGAGE Consortium, 2010, In : PLoS Genetics. 6, 6, 10 p., e1000976.

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USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

Laurila, P-P., Soronen, J., Kooijman, S., Forsstrom, S., Boon, M. R., Surakka, I., Kaiharju, E., Coomans, C. P., Van den Berg, S. A. A., Autio, A., Sarin, A-P., Kettunen, J., Tikkanen, E., Manninen, T., Metso, J., Silvennoinen, R., Merikanto, K., Ruuth, M., Perttila, J., Makela, A. & 27 others, Isomi, A., Tuomainen, A. M., Tikka, A., Ramadan, U. A., Seppala, I., Lehtimaki, T., Eriksson, J., Havulinna, A., Jula, A., Karhunen, P. J., Salomaa, V., Perola, M., Ehnholm, C., Lee-Rueckert, M., Van Eck, M., Roivainen, A., Taskinen, M-R., Palotie, L., Mervaala, E., Jalanko, A., Hohtola, E., Olkkonen, V. M., Ripatti, S., Kovanen, P. T., Rensen, P. C. N., Suomalainen, A. & Jauhiainenit, M., 27 Jan 2016, In : Science translational medicine. 8, 323, 19 p., ARTN 323ra13.

Research output: Contribution to journalArticleScientificpeer-review

Using ancestry-informative markers to identify fine structure across 15 populations of European origin

Huckins, L. M., Boraska, V., Franklin, C. S., Floyd, J. A. B., Southam, L., Sullivan, P. F., Bulik, C. M., Collier, D. A., Tyler-Smith, C., Zeggini, E., Tachmazidou, I., GCAN, WTCCC3, Kaprio, J., Keski-Rahkonen, A., Raevuori, A. H., Palotie, A. & Ripatti, S., Oct 2014, In : European Journal of Human Genetics. 22, 10, p. 1190-1200 11 p.

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Using Bayes' theorem in behavioural crime linking of serial homicide

Salo, B., Siren, J., Corander, J., Zappala, A., Bosco, D., Mokros, A. & Santtila, P., Sep 2013, In : Legal and Criminological Psychology. 18, 2, p. 356-370 15 p.

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Vain ongelmayksilöihin kohdistuva hylkeenmetsästys vähentää kalavahinkoja

Ahola, M., Jounela, P., Kauhala, K. & Vanhatalo, J., 20 Dec 2014, In : Turun Sanomat. 2014

Research output: Contribution to journalArticleGeneral public

Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk

Walsh, K. M., Codd, V., Smirnov, I. V., Rice, T., Decker, P. A., Hansen, H. M., Kollmeyer, T., Kosel, M. L., Molinaro, A. M., McCoy, L. S., Bracci, P. M., Cabriga, B. S., Pekmezci, M., Zheng, S., Wiemels, J. L., Pico, A. R., Tihan, T., Berger, M. S., Chang, S. M., Prados, M. D. & 15 others, Lachance, D. H., O'Neill, B. P., Sicotte, H., Eckel-Passow, J. E., van der Harst, P., Wiencke, J. K., Samani, N. J., Jenkins, R. B., Wrensch, M. R., ENGAGE Consortium Telomere Grp, Ripatti, S. O., Palotie, A., Eriksson, J., Kaprio, J. & Hovatta, I., Jul 2014, In : Nature Genetics. 46, 7, p. 731-735 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

Orlando, G., Law, P. J., Palin, K., Tuupanen, S., Gylfe, A., Hanninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Kaprio, J., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Ripatti, S., Palotie, A. & 37 others, Järvinen, H., Renkonen-Sinisalo, L., Lepisto, A., Bohm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Tenesa, A., Farrington, S., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Buchanan, D. D., Win, A. K., Hopper, J., Jenkins, M., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Taipale, J., Cheadle, J. P., Dunlop, M. G., Tomlinson, I. P., Aaltonen, L. A. & Houlston, R. S., 1 Jun 2016, In : Human Molecular Genetics. 25, 11, p. 2349-2359 11 p.

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Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study

Cnossen, M. C., Huijben, J. A., van der Jagt, M., Volovici, V., van Essen, T., Polinder, S., Nelson, D., Ercole, A., Stocchetti, N., Citerio, G., Peul, W. C., Maas, A. I. R., Menon, D., Steyerberg, E. W., Lingsma, H. F., CENTER-TBI Investigators, Palotie, A., Pirinen, M., Raj, R. & Ripatti, S., 6 Sep 2017, In : Critical Care. 21, 12 p., 233.

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Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study

van Essen, T. A., den Boogert, H. F., Cnossen, M. C., CENTER-TBI Investigators Partici, Kaukonen, M., Kivisaari, R., Piippo-Karjalainen, A., Raj, R., Tanskanen, P., Palotie, A., Pirinen, M. & Ripatti, S., Mar 2019, In : Acta Neurochirurgica. 161, 3, p. 435-449 15 p.

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Volume of Metric Balls in High-Dimensional Complex Grassmann Manifolds

Pitaval, R-A., Wei, L., Tirkkonen, O. & Corander, J., Sep 2016, In : IEEE Transactions on Information Theory. 62, 9, p. 5105-5116 12 p.

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What's in a Name? Species-Wide Whole-Genome Sequencing Resolves Invasive and Noninvasive Lineages of Salmonella enterica Serotype Paratyphi B

Connor, T. R., Owen, S. V., Langridge, G., Connell, S., Nair, S., Reuter, S., Dallman, T. J., Corander, J., Tabing, K. C., Le Hello, S., Fookes, M., Doublet, B., Zhou, Z., Feltwell, T., Ellington, M. J., Herrera, S., Gilmour, M., Cloeckaert, A., Achtman, M., Parkhill, J. & 5 others, Wain, J., De Pinna, E., Weill, F-X., Peters, T. & Thomson, N., 2016, In : mBio. 7, 4, 9 p., e00527-16.

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Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom

Chheda, H., Palta, P., Pirinen, M., McCarthy, S., Walter, K., Koskinen, S., Salomaa, V., Daly, M., Durbin, R., Palotie, A., Aittokallio, T., Ripatti, S. & Sequencing Initiative Suomi SISu P, Apr 2017, In : European Journal of Human Genetics. 25, 4, p. 477-484 8 p.

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Women's and men's sexual preferences and activities with respect to the partner's age: evidence for female choice

Antfolk, J., Salo, B., Alanko, K., Bergen, E., Corander, J., Sandnabba, N. K. & Santtila, P., Jan 2015, In : Evolution and Human Behavior. 36, 1, p. 73-79 7 p.

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Work-Related Exhaustion and Telomere Length: A Population-Based Study

Ahola, K., Siren, I., Kivimaki, M., Ripatti, S., Aromaa, A., Lönnqvist, J. & Hovatta, I., 2012, In : PLoS One. 7, 7, p. Article Number: e40186 7 p.

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