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2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

Zillikens, M. C., Demissie, S., Hsu, Y-H., Yerges-Armstrong, L. M., Chou, W-C., Stolk, L., Livshits, G., Broer, L., Johnson, T., Koller, D. L., Kutalik, Z., Luan, J., Malkin, I., Ried, J. S., Smith, A. V., Thorleifsson, G., Vandenput, L., Zhao, J. H., Zhang, W., Aghdassi, A. & 173 others, Akesson, K., Amin, N., Baier, L. J., Barroso, I., Bennett, D. A., Bertram, L., Biffar, R., Bochud, M., Boehnke, M., Borecki, I. B., Buchman, A. S., Byberg, L., Campbell, H., Obanda, N. C., Cauley, J. A., Cawthon, P. M., Cederberg, H., Chen, Z., Cho, N. H., Choi, H. J., Claussnitzer, M., Collins, F., Cummings, S. R., De Jager, P. L., Demuth, I., Dhonukshe-Rutten, R. A. M., Diatchenko, L., Eiriksdottir, G., Enneman, A. W., Erdos, M., Eriksson, J. G., Eriksson, J., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Garcia, M., Gieger, C., Girke, T., Glazer, N. L., Grallert, H., Grewal, J., Han, B-G., Hanson, R. L., Hayward, C., Hofman, A., Hoffman, E. P., Homuth, G., Hsueh, W-C., Hubal, M. J., Hubbard, A., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J-O., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K-T., Kilpainen, T. O., Klopp, N., Kloth, J. S. L., Koistinen, H. A., Kraus, W. E., Kritchevsky, S., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Launer, L. J., Lee, J-Y., Lerch, M. M., Lewis, J. R., Lind, L., Lindgren, C., Liu, Y., Liu, T., Liu, Y., Ljunggren, O., Lorentzon, M., Luben, R. N., Maixner, W., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellstrom, D., Melov, S., Michaelsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Newman, A., Nielson, C. M., O'Connell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Parker, S. C. J., Peacock, M., Perola, M., Peters, A., Polasek, O., Prince, R. L., Raikkonen, K., Ralston, S. H., Ripatti, S., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schadt, E. E., Schipf, S., Scott, L., Sehmi, J., Shen, J., Shin, C. S., Sigurdsson, G., Smith, S., Soranzo, N., Stancakova, A., Steinhagen-Thiessen, E., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Tan, S-T., Tarnopolsky, M. A., Thompson, P., Thomson, C. A., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Tuomilehto, J., van Schoor, N. M., Verma, A., Vollenweider, P., Voelzke, H., Wactawski-Wende, J., Walker, M., Weedon, M. N., Welch, R., Wichmann, H. -E., Widen, E., Williams, F. M. K., Wilson, J. F., Wright, N. C., Xie, W., Yu, L., Zhou, Y., Chambers, J. C., Doring, A., van Duijn, C. M., Econs, M. J., Gudnason, V., Kooner, J. S., Psaty, B. M., Spector, T. D., Stefansson, K., Rivadeneira, F., Uitterlinden, A. G., Wareham, N. J., Ossowski, V., Waterworth, D., Loos, R. J. F., Karasik, D., Harris, T. B., Ohlsson, C. & Kiel, D. P., 19 Jul 2017, In : Nature Communications. 8, 13 p., 80.

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Learning discrete decomposable graphical models via constraint optimization

Janhunen, T., Gebser, M., Rintanen, J., Nyman, H., Pensar, J. & Corander, J., Jan 2017, In : Statistics and Computing. 27, 1, p. 115-130 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

Rodriguez-Broadbent, H., Law, P. J., Sud, A., Palin, K., Tuupanen, S., Gylfe, A., Hanninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Ripatti, S., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Palotie, A. & 36 others, Renkonen-Sinisalo, L., Lepisto, A., Bohm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Passarelli, M. N., Figueiredo, J. C., Buchanan, D. D., Win, A. K., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Aaltonen, L. A., Cheadle, J. P., Tomlinson, I. P., Dunlop, M. G. & Houlston, R. S., 15 Jun 2017, In : International Journal of Cancer. 140, 12, p. 2701-2708 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Modeling the spatial distribution of larval fish abundance provides essential information for management

Kallasvuo, M., Vanhatalo, J. & Veneranta, L., May 2017, In : Canadian Journal of Fisheries and Aquatic Sciences. 74, 5, p. 636-649 14 p.

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Neuregulin signaling pathway in smoking behavior

Gupta, R., Qaiser, B., He, L., Hiekkalinna, T. S., Zheutlin, A. B., Therman, S., Ollikainen, M., Ripatti, S., Perola, M., Salomaa, V., Milani, L., Cannon, T. D., Madden, P. A. F., Korhonen, T., Kaprio, J. & Loukola, A., 22 Aug 2017, In : Translational Psychiatry. 7, 8 p., 1212.

Research output: Contribution to journalArticleScientificpeer-review

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Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Wain, L. V., Vaez, A., Jansen, R., Joehanes, R., van der Most, P. J., Erzurumluoglu, A. M., O'Reilly, P. F., Cabrera, C. P., Warren, H. R., Rose, L. M., Verwoert, G. C., Hottenga, J-J., Strawbridge, R. J., Esko, T., Arking, D. E., Hwang, S-J., Guo, X., Kutalik, Z., Trompet, S., Shrine, N. & 33 others, Teumer, A., Ried, J. S., Bis, J. C., Smith, A. V., Amin, N., Nolte, I. M., Lyytikainen, L-P., Mahajan, A., Wareham, N. J., Hofer, E., Joshi, P. K., Kristiansson, K., Traglia, M., Havulinna, A. S., Goel, A., Nalls, M. A., Sober, S., Vuckovic, D., Luan, J., Del Greco M, F., Ayers, K. L., Marrugat, J., Ruggiero, D., Lopez, L. M., Niiranen, T., Enroth, S., Palotie, A., Ripatti, S., Sarin, A-P., Perola, M., BIOS Consortium, Lifelines Cohort Study & Understanding Soc Sci Grp, Sep 2017, In : Hypertension. 70, 3, p. E4-+ 49 p.

Research output: Contribution to journalArticleScientificpeer-review

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Predicting ice-induced load amplitudes on ship bow conditional on ice thickness and ship speed in the Baltic Sea

Kotilainen, M., Vanhatalo, J. P., Suominen, M. & Kujala, P., Mar 2017, In : Cold Regions Science and Technology. 135, p. 116–126 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Preparing for the unprecedented - Towards quantitative oil risk assessment in the Arctic marine areas

Nevalainen, M., Helle, I. & Vanhatalo, J., 15 Jan 2017, In : Marine Pollution Bulletin. 114, 1, p. 90-101 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

May-Wilson, S., Sud, A., Law, P. J., Palin, K., Tuupanen, S., Gylfe, A., Hänninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Ripatti, S., Palotie, A. & 34 others, Renkonen-Sinisalo, L., Lepisto, A., Böhm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Fisher, D., Kerr, R., Kerr, D., Passarelli, M. N., Figueiredo, J. C., Buchanan, D. D., Win, A. K., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Aaltonen, L. A., Cheadle, J. P., Tomlinson, I. P., Dunlop, M. G. & Houlston, R. S., Oct 2017, In : European Journal of Cancer. 84, p. 228-238 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Sepelvaltimotautiriskin arviointi genomitietoa hyödyntämällä

Widén, E. & Ripatti, S., 2017, In : Duodecim. 133, 8, p. 776-781 6 p.

Research output: Contribution to journalArticleProfessional

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Spatiotemporal modelling of crown-of-thorns starfish outbreaks on the Great Barrier Reef to inform control strategies

Vanhatalo, J. P., Hosack, G. & Sweatman, H., Jan 2017, In : Journal of Applied Ecology. 54, 1, p. 188-197

Research output: Contribution to journalArticleScientificpeer-review

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Stratified Gaussian graphical models

Nyman, H., Pensar, J. & Corander, J., 2017, In : Communications in Statistics: Theory and Methods. 46, 11, p. 5556-5578 23 p.

Research output: Contribution to journalArticleScientificpeer-review

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Suomi luomassa genomiikan ja terveystiedon internetiä

Palotie, A. & Ripatti, S., 2017, In : Duodecim. 133, 8, p. 771-775 5 p.

Research output: Contribution to journalArticleProfessional

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Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study

Cnossen, M. C., Huijben, J. A., van der Jagt, M., Volovici, V., van Essen, T., Polinder, S., Nelson, D., Ercole, A., Stocchetti, N., Citerio, G., Peul, W. C., Maas, A. I. R., Menon, D., Steyerberg, E. W., Lingsma, H. F., CENTER-TBI Investigators, Palotie, A., Pirinen, M., Raj, R. & Ripatti, S., 6 Sep 2017, In : Critical Care. 21, 12 p., 233.

Research output: Contribution to journalArticleScientificpeer-review

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Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom

Chheda, H., Palta, P., Pirinen, M., McCarthy, S., Walter, K., Koskinen, S., Salomaa, V., Daly, M., Durbin, R., Palotie, A., Aittokallio, T., Ripatti, S. & Sequencing Initiative Suomi SISu P, Apr 2017, In : European Journal of Human Genetics. 25, 4, p. 477-484 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2016

Analysis of differential splicing suggests different modes of short-term splicing regulation

Topa, H. & Honkela, A., 15 Jun 2016, In : Bioinformatics. 32, 12, p. 147-155 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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An object oriented Python interface for atomistic simulations

Hynninen, T., Himanen, L., Parkkinen, V., Musso, T., Corander, J. & Foster, A. S., Jan 2016, In : Computer Physics Communications. 198, p. 230-237 8 p.

Research output: Contribution to journalArticleScientificpeer-review

A reference panel of 64,976 haplotypes for genotype imputation

McCarthy, S., Das, S., Kretzschmar, W., Delaneau, O., Wood, A. R., Teumer, A., Kang, H. M., Fuchsberger, C., Danecek, P., Sharp, K., Luo, Y., Sidorel, C., Kwong, A., Timpson, N., Koskinen, S., Vrieze, S., Scott, L. J., Zhang, H., Mahajan, A., Veldink, J. & 31 others, Peters, U., Pato, C., van Duijn, C. M., Gillies, C. E., Gandin, I., Mezzavilla, M., Gilly, A., Cocca, M., Traglia, M., Angius, A., Barrett, J. C., Boomsma, D., Branham, K., Breen, G., Brummett, C. M., Busonero, F., Campbell, H., Chan, A., Che, S., Chew, E., Collins, F. S., Corbin, L. J., Smith, G. D., Dedoussis, G., Dorr, M., Farmaki, A-E., Ferrucci, L., Groop, L., Palotie, A., Ripatti, S. & Haplotype Reference Consortium, Oct 2016, In : Nature Genetics. 48, 10, p. 1279-1283 5 p.

Research output: Contribution to journalArticleScientificpeer-review

A tribute to Mats Gyllenberg, on the occasion of his 60th birthday

Corander, J., Diekmann, O. & Koski, T., Mar 2016, In : Journal of mathematical biology. 72, 4, p. 793-795 3 p.

Research output: Contribution to journalArticleScientific

Bayesian identification of bacterial strains from sequencing data

Sankar, A., Malone, B. M., Bayliss, S. C., Pascoe, B., Méric, G., Hitchings, M. D., Sheppard, S. K., Feil, E. J., Corander, J. I. & Honkela, A. J. H., 25 Aug 2016, In : Microbial Genomics. 2, 8, 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Bayesian Optimization for Likelihood-Free Inference of Simulator-Based Statistical Models

Gutmann, M. U. & Corander, J., Aug 2016, In : Journal of Machine Learning Research. 17, 47 p.

Research output: Contribution to journalArticleScientificpeer-review

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Combined Analysis of Variation in Core, Accessory and Regulatory Genome Regions Provides a Super-Resolution View into the Evolution of Bacterial Populations

McNally, A., Oren, Y., Kelly, D., Pascoe, B., Dunn, S., Sreecharan, T., Vehkala, M., Välimäki, N., Prentice, M. B., Ashour, A., Avram, O., Pupko, T., Dobrindt, U., Literak, I., Guenther, S., Schaufler, K., Wieler, L. H., Zong Zhiyong, Sheppard, S. K., McInerney, J. O. & 1 others, Corander, J., Sep 2016, In : PLoS Genetics. 12, 9, 16 p., 1006280.

Research output: Contribution to journalArticleScientificpeer-review

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Computing exact clustering posteriors with subset convolution

Kohonen, J. & Corander, J., 2016, In : Communications in Statistics: Theory and Methods. 45, 10, p. 3048-3058 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Context-specific independence in graphical log-linear models

Nyman, H., Pensar, J., Koski, T. & Corander, J., Dec 2016, In : Computational Statistics. 31, 4, p. 1493-1512 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

Sieberts, S. K., Zhu, F., Garcia-Garcia, J., Stahl, E., Pratap, A., Pandey, G., Pappas, D., Aguilar, D., Anton, B., Bonet, J., Eksi, R., Fornes, O., Guney, E., Li, H., Marin, M. A., Panwar, B., Planas-Iglesias, J., Poglayen, D., Cui, J., Falcao, A. O. & 31 others, Suver, C., Hoff, B., Balagurusamy, V. S. K., Dillenberger, D., Neto, E. C., Norman, T., Aittokallio, T., Ammad-ud-din, M., Azencott, C-A., Bellon, V., Boeva, V., Bunte, K., Chheda, H., Cheng, L., Corander, J., Dumontier, M., Goldenberg, A., Gopalacharyulu, P., Hajiloo, M., Hidru, D., Jaiswal, A., Kaski, S., Khalfaoui, B., Khan, S. A., Kramer, E. R., Marttinen, P., Pirinen, M., Saarela, J., Tang, J., Wennerberg, K. & Rheumatoid Arth Challenge, Aug 2016, In : Nature Communications. 7, 9 p., 12460.

Research output: Contribution to journalArticleScientificpeer-review

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Detailed temperature mapping-Warming characterizes archipelago zones

Veneranta, L., Vanhatalo, J. & Urho, L., 5 Dec 2016, In : Estuarine, Coastal and Shelf Science. 182, p. 123-135 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Downscaling and extrapolating dynamic seasonal marine forecasts for coastal ocean users

Vanhatalo, J. P., Hobday, A. J., Little, L. R. & Spillman, C. M., Apr 2016, In : Ocean Modelling. 100, p. 20-30 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

Nowak, C., Salihovic, S., Ganna, A., Brandmaier, S., Tukiainen, T., Broeckling, C. D., Magnusson, P. K., Prenni, J. E., Wang-Sattler, R., Peters, A., Strauch, K., Meitinger, T., Giedraitis, V., Arnlov, J., Berne, C., Gieger, C., Ripatti, S., Lind, L., Pedersen, N. L., Sundstrom, J. & 2 others, Ingelsson, E. & Fall, T., Oct 2016, In : PLoS Genetics. 12, 10, 19 p., 1006379.

Research output: Contribution to journalArticleScientificpeer-review

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Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Hinney, A., Kesselmeier, M., Jall, S., et al., Hebebrand, J., GENETIC CONSORTIUM FOR ANOREXIA NERVOSA (GCAN), WELLCOME TRUST CASE CONTROL CONSORTIUM 3 (WTCCC3), GENETIC INVESTIGATION OF ANTHROPOMETRIC TRAITS CONSORTIUM (GIANT), EARLY GROWTH GENETICS CONSORTIUM (EGG), THE PRICE FOUNDATION COLLABORATIVE GROUP, Raevuori-Helkamaa, A., Palotie, A. & Ripatti, S., 17 May 2016, In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

Research output: Contribution to journalArticleScientificpeer-review

FINEMAP: efficient variable selection using summary data from genome-wide association studies

Benner, C., Spencer, C. C. A., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., 15 May 2016, In : Bioinformatics. 32, 10, p. 1493-1501 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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FLOG: Multivariate R Tool for Exploring Biolog Phenotype Microarray Data

Vehkala, M. E., Shubin, M. & Corander, J. I., 16 Aug 2016, (In preparation) In : PLoS One.

Research output: Contribution to journalArticleScientificpeer-review

Genetic Risk Scores Predict Recurrence of Acute Coronary Syndrome

Vaara, S., Tikkanen, E., Parkkonen, O., Lokki, M-L., Ripatti, S., Perola, M., Nieminen, M. S. & Sinisalo, J., Apr 2016, In : Circulation. Cardiovascular genetics. 9, 2, p. 172-178 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic support for the causal role of insulin in coronary heart disease

Tikkanen, E., Pirinen, M., Sarin, A-P., Havulinna, A. S., Mannisto, S., Saltevo, J., Lokki, M-L., Sinisalo, J., Lundqvist, A., Jula, A., Salomaa, V. & Ripatti, S., 2016, In : Diabetologia. 59, 11, p. 2369-2377 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Genome-Wide Meta-Analysis of Sciatica in Finnish Population

Lemmelä, S., Solovieva, S., Shiri, R., Benner, C., Heliovaara, M., Kettunen, J., Anttila, V., Ripatti, S., Perola, M., Seppala, I., Juonala, M., Kahonen, M., Salomaa, V., Viikari, J., Raitakari, O. T., Lehtimaki, T., Palotie, A., Viikari-Juntura, E. & Husgafvel-Pursiainen, K., 20 Oct 2016, In : PLoS One. 11, 10, 18 p., 0163877.

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Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

Kettunen, J., Demirkan, A., Wurtz, P., Draisma, H. H. M., Haller, T., Rawal, R., Vaarhorst, A., Kangas, A. J., Lyytikäinen, L-P., Pirinen, M., Pool, R., Sarin, A-P., Soininen, P., Tukiainen, T., Wang, Q., Tiainen, M., Tynkkynen, T., Amin, N., Zeller, T., Beekman, M. & 30 others, Deelen, J., van Dijk, K. W., Esko, T., Hottenga, J-J., van Leeuwen, E. M., Lehtimaki, T., Mihailov, E., Rose, R. J., de Craen, A. J. M., Gieger, C., Kahonen, M., Perola, M., Blankenberg, S., Savolainen, M. J., Verhoeven, A., Viikari, J., Willemsen, G., Boomsma, D. I., van Duijn, C. M., Eriksson, J., Jula, A., Jarvelin, M-R., Kaprio, J., Metspalu, A., Raitakari, O., Salomaa, V., Slagboom, P. E., Waldenberger, M., Ripatti, S. & Ala-Korpela, M., Mar 2016, In : Nature Communications. 7, 9 p., 11122.

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Genome-wide time-to-event analysis on smoking progression stages in a family-based study

He, L., Pitkäniemi, J., Heikkila, K., Chou, Y-L., Madden, P. A. F., Korhonen, T., Sarin, A-P., Ripatti, S., Kaprio, J. & Loukola, A., May 2016, In : Brain and Behavior. 6, 5, 14 p., 00462.

Research output: Contribution to journalArticleScientificpeer-review

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Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

Spjuth, O., Krestyaninova, M., Hastings, J., Shen, H-Y., Heikkinen, J., Waldenberger, M., Langhammer, A., Ladenvall, C., Esko, T., Persson, M-A., Heggland, J., Dietrich, J., Ose, S., Gieger, C., Ried, J. S., Peters, A., Fortier, I., de Geus, E. J. C., Klovins, J., Zaharenko, L. & 16 others, Willemsen, G., Hottenga, J-J., Litton, J-E., Karvanen, J., Boomsma, D. I., Groop, L., Rung, J., Palmgren, J., Pedersen, N. L., McCarthy, M. I., van Duijn, C. M., Hveem, K., Metspalu, A., Ripatti, S., Prokopenko, I. & Harris, J. R., Apr 2016, In : European Journal of Human Genetics. 24, 4, p. 521-528 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Hydrographic responses to regional covariates across the Kara Sea

Mäkinen, J. A-E. & Vanhatalo, J. P., Dec 2016, In : Journal of Geophysical Research : Oceans. 121, 12, p. 8872-8887 16 p.

Research output: Contribution to journalArticleScientificpeer-review

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Identifying Multiple Potential Metabolic Cycles in Time-Series from Biolog Experiments

Shubin, M., Schaufler, K., Tedin, K., Vehkala, M. & Corander, J., 27 Sep 2016, In : PLoS One. 11, 9, 14 p., 0162276.

Research output: Contribution to journalArticleScientificpeer-review

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KardioKompassi yhdistää perimän ja perinteiset riskitekijät sepelvaltimotaudin ehkäisyssä

Ripatti, S. & Widén, E., 2016, In : Duodecim. 132, 10, p. 897-899 3 p.

Research output: Contribution to journalArticleScientific

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Low-Rank Doubly Stochastic Matrix Decomposition for Cluster Analysis

Yang, Z., Corander, J. & Oja, E., 2016, In : Journal of Machine Learning Research. 17, 187, p. 1-25 25 p., 1.

Research output: Contribution to journalArticleScientificpeer-review

Marginal and simultaneous predictive classification using stratified graphical models

Nyman, H., Xiong, J., Pensar, J. & Corander, J., Sep 2016, In : Advances in Data Analysis and Classification. 10, 3, p. 305-326 22 p.

Research output: Contribution to journalArticleScientificpeer-review

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

Jarvis, D., Mitchell, J. S., Law, P. J., Palin, K., Tuupanen, S., Gylfe, A., Hanninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Kaprio, J., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Ripatti, S. & 37 others, Palotie, A., Järvinen, H., Renkonen-Sinisalo, L., Lepistö, A., Bohm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Buchanan, D. D., Win, A. K., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Taipale, J., Aaltonen, L. A., Cheadle, J. P., Dunlop, M. G., Tomlinson, I. P. & Houlston, R. S., 12 Jul 2016, In : British Journal of Cancer. 115, 2, p. 266-272 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems

Shu, L., Zhao, Y., Kurt, Z., Byars, S. G., Tukiainen, T., Kettunen, J., Orozco, L. D., Pellegrini, M., Lusis, A. J., Ripatti, S., Zhang, B., Inouye, M., Makinen, V-P. & Yang, X., 4 Nov 2016, In : BMC Genomics. 17, 16 p., 874.

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Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

van Leeuwen, E. M., Sabo, A., Bis, J. C., Huffman, J. E., Manichaikul, A., Smith, A. V., Feitosa, M. F., Demissie, S., Joshi, P. K., Duan, Q., Marten, J., van Klinken, J. B., Surakka, I., Nolte, I. M., Zhang, W., Mbarek, H., Li-Gao, R., Trompet, S., Verweij, N., Evangelou, E. & 31 others, Lyytikainen, L-P., Tayo, B. O., Deelen, J., van der Most, P. J., van der Laan, S. W., Arking, D. E., Morrison, A., Dehghan, A., Franco, O. H., Hofman, A., Rivadeneira, F., Sijbrands, E. J., Uitterlinden, A. G., Mychaleckyj, J. C., Campbell, A., Hocking, L. J., Padmanabhan, S., Brody, J. A., Rice, K. M., White, C. C., Harris, T., Isaacs, A., Campbell, H., Lange, L. A., Rudan, I., Kolcic, I., Navarro, P., Zemunik, T., Salomaa, V., Ripatti, S. & CHARGE Lipids Working Grp, Jul 2016, In : Journal of Medical Genetics. 53, 7, p. 441-449 9 p.

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metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

Cichonska, A., Rousu, J., Marttinen, P., Kangas, A. J., Soininen, P., Lehtimaki, T., Raitakari, O. T., Jarvelin, M-R., Salomaa, V., Ala-Korpela, M., Ripatti, S. & Pirinen, M., 1 Jul 2016, In : Bioinformatics. 32, 13, p. 1981-1989 9 p.

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Monomorphic genotypes within a generalist lineage of Campylobacter jejuni show signs of global dispersion

Llarena, A-K., Zhang, J., Vehkala, M., Välimäki, N., Hakkinen, M., Hänninen, M-L., Roasto, M., Mäesaar, M., Taboada, E., Barker, D., Garofolo, G., Cammà, C., Di Giannatale, E., Corander, J. & Rossi, M., 1 Oct 2016, In : Microbial Genomics. 2, 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Multiple Output Regression with Latent Noise

Gillberg, J., Marttinen, P., Pirinen, M., Kangas, A. J., Soininen, P., Ali, M., Havulinna, A. S., Järvelin, M-R., Ala-Korpela, M. & Kaski, S., 1 Jan 2016, In : Journal of Machine Learning Research. 17, 1, p. 4170-4204 35 p.

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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, A. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S. & 239 others, Lagou, V., Li, R., Li, X., Locke, A., Lu, C., Magi, R., Perry, J. R. B., Pers, T. H., Qi, Q., Sanna, M., Schmidt, E. M., Scott, W. R., Shungin, D., Teumer, A., Vinkhuyzen, A. A. E., Walker, R. W., Westra, H-J., Zhang, M., Zhang, W., Zhao, J. H., Zhu, Z., Afzal, U., Ahluwalia, T. S., Bakker, S. J. L., Bellis, C., Bonnefond, A., Borodulin, K., Buchman, A. S., Cederholm, T., Choh, A. C., Choi, H. J., Curran, J. E., de Groot, L. C. P. G. M., De Jager, P. L., Dhonukshe-Rutten, R. A. M., Enneman, A. W., Eury, E., Evans, D. S., Forsen, T., Friedrich, N., Fumeron, F., Garcia, M. E., Gartner, S., Han, B-G., Havulinna, A. S., Hayward, C., Hernandez, D., Hillege, H., Ittermann, T., Kent, J. W., Kolcic, I., Laatikainen, T., Lahti, J., Leach, I. M., Lee, C. G., Lee, J-Y., Liu, T., Liu, Y., Lobbens, S., Loh, M., Lyytikainen, L-P., Medina-Gomez, C., Michaelsson, K., Nalls, M. A., Nielson, C. M., Oozageer, L., Pascoe, L., Paternoster, L., Polasek, O., Ripatti, S., Sarzynski, M. A., Shin, C. S., Narancic, N. S., Spira, D., Srikanth, P., Steinhagen-Thiessen, E., Sung, Y. J., Swart, K. M. A., Taittonen, L., Tanaka, T., Tikkanen, E., van der Velde, N., van Schoor, N. M., Verweij, N., Wright, A. F., Yu, L., Zmuda, J. M., Pellikka, N., Forrester, T., Grarup, N., Jackson, A. U., Kristiansson, K., Kuulasmaa, T., Kuusisto, J., Lichtner, P., Luan, J., Mahajan, A., Mannisto, S., Palmer, C. D., Ried, J. S., Scott, R. A., Stancakova, A., Wagner, P. J., Demirkan, A., Doring, A., Gudnason, V., Kiel, D. P., Kuhnel, B., Mangino, M., Mcknight, B., Menni, C., O'Connell, J. R., Oostra, B. A., Shuldiner, A. R., Song, K., Vandenput, L., van Duijn, C. M., Vollenweider, P., White, C. C., Boehnke, M., Boettcher, Y., Cooper, R. S., Forouhi, N. G., Gieger, C., Grallert, H., Hingorani, A., Jorgensen, T., Jousilahti, P., Kivimaki, M., Kumari, M., Laakso, M., Langenberg, C., Linneberg, A., Luke, A., Mckenzie, C. A., Palotie, A., Pedersen, O., Peters, A., Strauch, K., Tayo, B. O., Wareham, N. J., Bennett, D. A., Bertram, L., Blangero, J., Bluher, M., Bouchard, C., Campbell, H., Cho, N. H., Cummings, S. R., Czerwinski, S. A., Demuth, I., Eckardt, R., Eriksson, J. G., Ferrucci, L., Franco, O. H., Froguel, P., Gansevoort, R. T., Hansen, T., Harris, T. B., Hastie, N., Heliovaara, M., Hofman, A., Jordan, J. M., Jula, A., Kahonen, M., Kajantie, E., Knekt, P. B., Koskinen, S., Kovacs, P., Lehtimaki, T., Lind, L., Liu, Y., Orwoll, E. S., Osmond, C., Perola, M., Perusse, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Rivadeneira, F., Rudan, I., Salomaa, V., Sorensen, T. I. A., Stumvoll, M., Tonjes, A., Towne, B., Tranah, G. J., Tremblay, A., Uitterlinden, A. G., van der Harst, P., Vartiainen, E., Viikari, J. S., Vitart, V., Vohl, M-C., Volzke, H., Walker, M., Wallaschofski, H., Wild, S., Wilson, J. F., Yengo, L., Bishop, D. T., Borecki, I. B., Chambers, J. C., Cupples, L. A., Dehghan, A., Deloukas, P., Fatemifar, G., Fox, C., Furey, T. S., Franke, L., Han, J., Hunter, D. J., Karjalainen, J., Karpe, F., Kaplan, R. C., Kooner, J. S., McCarthy, M. I., Murabito, J. M., Morris, A. P., Bishop, J. A. N., North, K. E., Ohlsson, C., Ong, K. K., Prokopenko, I., Richards, J. B., Schadt, E. E., Spector, T. D., Widen, E., Willer, C. J., Yang, J., Ingelsson, E., Mohlke, K. L., Hirschhorn, J. N., Pospisilik, J. A., Zillikens, M. C., Lindgren, C., Kilpelainen, T. O. & Loos, R. J. F., Feb 2016, In : Nature Communications. 7, 15 p., 10495.

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No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

Loley, C., Alver, M., Assimes, T. L., Bjonnes, A., Goel, A., Gustafsson, S., Hernesniemi, J., Hopewell, J. C., Kanoni, S., Kleber, M. E., Lau, K. W., Lu, Y., Lyytikainen, L-P., Nelson, C. P., Nikpay, M., Qu, L., Salfati, E., Scholz, M., Tukiainen, T., Willenborg, C. & 58 others, Won, H-H., Zeng, L., Zhang, W., Anand, S. S., Beutner, F., Bottinger, E. P., Clarke, R., Dedoussis, G., Do, R., Esko, T., Eskola, M., Farrall, M., Gauguier, D., Giedraitis, V., Granger, C. B., Hall, A. S., Hamsten, A., Hazen, S. L., Huang, J., Kahonen, M., Kyriakou, T., Laaksonen, R., Lind, L., Lindgren, C., Magnusson, P. K. E., Marouli, E., Mihailov, E., Morris, A. P., Nikus, K., Pedersen, N., Rallidis, L., Salomaa, V., Shah, S. H., Stewart, A. F. R., Thompson, J. R., Zalloua, P. A., Chambers, J. C., Collins, R., Ingelsson, E., Iribarren, C., Karhunen, P. J., Kooner, J. S., Lehtimaki, T., Loos, R. J. F., Maerz, W., McPherson, R., Metspalu, A., Reilly, M. P., Ripatti, S., Sanghera, D. K., Thiery, J., Watkins, H., Deloukas, P., Kathiresan, S., Samani, N. J., Schunkert, H., Erdmann, J. & Koenig, I. R., 12 Oct 2016, In : Scientific Reports. 6, 9 p., 35278.

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