Publications 2001 2020

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2016

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 44 othersMihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samue, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stancakova, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Gjesing, A. P., Kontto, J., Perola, M., Shaw-Hawkins, S., Havulinna, A. S., Kajantie, E., Tuomi, T., Groop, L., Palotie, A., Ripatti, S., CHARGE Heart Failure Consortiumm, EchoGen Consortiumm, Metastroke Consortiumm, Giant Consortiumm, EPIC-InterAct Consortium, Lifelines Cohort Study, Wellcome Trust Case Control Consor, Understanding Soc Sci Grp, EPIC-CVD Consortium, CHARGE Exome Chip Blood Pressure C, T2D-GENES Consortium, GoT2DGenes Consortium, ExomeBP Consortium & CHD Exome Consortium, Oct 2016, In : Nature Genetics. 48, 10, p. 1151-1161 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Transcriptome Remodeling Contributes to Epidemic Disease Caused by the Human Pathogen Streptococcus pyogenes

Beres, S. B., Kachroo, P., Nasser, W., Olsen, R. J., Zhu, L., Flores, A. R., de la Riva, I., Paez-Mayorga, J., Jimenez, F. E., Cantu, C., Vuopio, J., Jalava, J., Kristinsson, K. G., Gottfredsson, M., Corander, J., Fittipaldi, N., Di Luca, M. C., Petrelli, D., Vitali, L. A., Raiford, A. & 2 othersJenkins, L. & Musser, J. M., 2016, In : mBio. 7, 3, 14 p., ARTN 00403-16.

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Understanding pneumococcal serotype 1 biology through population genomic analysis

Chaguza, C., Cornick, J. E., Harris, S. R., Andam, C. P., Bricio-Moreno, L., Yang, M., Yalcin, F., Ousmane, S., Govindpersad, S., Senghore, M., Ebruke, C., Du Plessis, M., Kiran, A. M., Pluschke, G., Sigauque, B., McGee, L., Klugman, K. P., Turner, P., Corander, J., Parkhill, J. & 10 othersCollard, J-M., Antonio, M., von Gottberg, A., Heyderman, R. S., French, N., Kadioglu, A., Hanage, W. P., Everett, D. B., Bentley, S. D. & PAGe Consortium, 8 Nov 2016, In : BMC Infectious Diseases. 16, 14 p., 649.

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USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

Laurila, P-P., Soronen, J., Kooijman, S., Forsstrom, S., Boon, M. R., Surakka, I., Kaiharju, E., Coomans, C. P., Van den Berg, S. A. A., Autio, A., Sarin, A-P., Kettunen, J., Tikkanen, E., Manninen, T., Metso, J., Silvennoinen, R., Merikanto, K., Ruuth, M., Perttila, J., Makela, A. & 27 othersIsomi, A., Tuomainen, A. M., Tikka, A., Ramadan, U. A., Seppala, I., Lehtimaki, T., Eriksson, J., Havulinna, A., Jula, A., Karhunen, P. J., Salomaa, V., Perola, M., Ehnholm, C., Lee-Rueckert, M., Van Eck, M., Roivainen, A., Taskinen, M-R., Palotie, L., Mervaala, E., Jalanko, A., Hohtola, E., Olkkonen, V. M., Ripatti, S., Kovanen, P. T., Rensen, P. C. N., Suomalainen, A. & Jauhiainenit, M., 27 Jan 2016, In : Science translational medicine. 8, 323, 19 p., ARTN 323ra13.

Research output: Contribution to journalArticleScientificpeer-review

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

Orlando, G., Law, P. J., Palin, K., Tuupanen, S., Gylfe, A., Hanninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Kaprio, J., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Ripatti, S., Palotie, A. & 37 othersJärvinen, H., Renkonen-Sinisalo, L., Lepisto, A., Bohm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Tenesa, A., Farrington, S., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Buchanan, D. D., Win, A. K., Hopper, J., Jenkins, M., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Taipale, J., Cheadle, J. P., Dunlop, M. G., Tomlinson, I. P., Aaltonen, L. A. & Houlston, R. S., 1 Jun 2016, In : Human Molecular Genetics. 25, 11, p. 2349-2359 11 p.

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Volume of Metric Balls in High-Dimensional Complex Grassmann Manifolds

Pitaval, R-A., Wei, L., Tirkkonen, O. & Corander, J., Sep 2016, In : IEEE Transactions on Information Theory. 62, 9, p. 5105-5116 12 p.

Research output: Contribution to journalArticleScientificpeer-review

What's in a Name? Species-Wide Whole-Genome Sequencing Resolves Invasive and Noninvasive Lineages of Salmonella enterica Serotype Paratyphi B

Connor, T. R., Owen, S. V., Langridge, G., Connell, S., Nair, S., Reuter, S., Dallman, T. J., Corander, J., Tabing, K. C., Le Hello, S., Fookes, M., Doublet, B., Zhou, Z., Feltwell, T., Ellington, M. J., Herrera, S., Gilmour, M., Cloeckaert, A., Achtman, M., Parkhill, J. & 5 othersWain, J., De Pinna, E., Weill, F-X., Peters, T. & Thomson, N., 2016, In : mBio. 7, 4, 9 p., e00527-16.

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2015

A Bayesian Predictive Model for Clustering Data of Mixed Discrete and Continuous Type

Blomstedt, P., Tang, J., Xiong, J., Granlund, C. & Corander, J., Mar 2015, In : IEEE Transactions on Pattern Analysis and Machine Intelligence. 37, 3, p. 489-498 10 p.

Research output: Contribution to journalArticleScientificpeer-review

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Nikpay, M., Goel, A., Won, H-H., Hall, L. M., Willenborg, C., Kanoni, S., Saleheen, D., Kyriakou, T., Nelson, C. P., Hopewell, J. C., Webb, T. R., Zeng, L., Dehghan, A., Alver, M., Armasu, S. M., Auro, K., Bjonnes, A., Chasman, D. I., Chen, S., Ford, I. & 132 othersFranceschini, N., Gieger, C., Grace, C., Gustafsson, S., Huang, J., Hwang, S-J., Kim, Y. K., Kleber, M. E., Lau, K. W., Lu, X., Lu, Y., Lyytikainen, L-P., Mihailov, E., Morrison, A. C., Pervjakova, N., Qu, L., Rose, L. M., Salfati, E., Saxena, R., Scholz, M., Smith, A. V., Tikkanen, E., Uitterlinden, A., Yang, X., Zhang, W., Zhao, W., de Andrade, M., de Vries, P. S., van Zuydam, N. R., Anand, S. S., Bertram, L., Beutner, F., Dedoussis, G., Frossard, P., Gauguier, D., Goodall, A. H., Gottesman, O., Haber, M., Han, B-G., Huang, J., Jalilzadeh, S., Kessler, T., Koenig, I. R., Lannfelt, L., Lieb, W., Lind, L., Lindgren, C. M., Lokki, M-L., Magnusson, P. K., Mallick, N. H., Mehra, N., Meitinger, T., Memon, F-R., Morris, A. P., Nieminen, M. S., Pedersen, N. L., Peters, A., Rallidis, L. S., Rasheed, A., Samuel, M., Shah, S. H., Sinisalo, J., Stirrups, K. E., Trompet, S., Wang, L., Zaman, K. S., Ardissino, D., Boerwinkle, E., Borecki, I. B., Bottinger, E. P., Buring, J. E., Chambers, J. C., Collins, R., Cupples, L. A., Danesh, J., Demuth, I., Elosua, R., Epstein, S. E., Esko, T., Feitosa, M. F., Franco, O. H., Franzosi, M. G., Granger, C. B., Gu, D., Gudnason, V., Hall, A. S., Hamsten, A., Harris, T. B., Hazen, S. L., Hengstenberg, C., Hofman, A., Ingelsson, E., Iribarren, C., Jukema, J. W., Karhunen, P. J., Kim, B-J., Kooner, J. S., Kullo, I. J., Lehtimaki, T., Loos, R. J. F., Melander, O., Metspalu, A., Maerz, W., Palmer, C. N., Perola, M., Quertermous, T., Rader, D. J., Ridker, P. M., Ripatti, S., Roberts, R., Salomaa, V., Sanghera, D. K., Schwartz, S. M., Seedorf, U., Stewart, A. F., Stott, D. J., Thiery, J., Zalloua, P. A., O'Donnell, C. J., Reilly, M. P., Assimes, T. L., Thompson, J. R., Erdmann, J., Clarke, R., Watkins, H., Kathiresan, S., McPherson, R., Deloukas, P., Schunkert, H., Samani, N. J., Farrall, M. & CARDIoGRAMplusC4D Consortium, Oct 2015, In : Nature Genetics. 47, 10, p. 1121-+ 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Adaptive importance sampling in signal processing

Bugallo, M. F., Martino, L. & Corander, J., Dec 2015, In : Digital Signal Processing. 47, p. 36-49 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

Haegg, S., Fall, T., Ploner, A., Maegi, R., Fischer, K., Draisma, H. H. M., Kals, M., de Vries, P. S., Dehghan, A., Willems, S. M., Sarin, A-P., Kristiansson, K., Nuotio, M-L., Havulinna, A. S., de Bruijn, R. F. A. G., Ikram, M. A., Kuningas, M., Stricker, B. H., Franco, O. H., Benyamin, B. & 44 othersGieger, C., Hall, A. S., Huikari, V., Jula, A., Jarvelin, M-R., Kaakinen, M., Kaprio, J., Kobl, M., Mangino, M., Nelson, C. P., Palotie, A., Samani, N. J., Spector, T. D., Strachan, D. P., Tobin, M. D., Whitfield, J. B., Uitterlinden, A. G., Salomaa, V., Syvanen, A-C., Kuulasmaa, K., Magnusson, P. K., Esko, T., Hofman, A., de Geus, E. J. C., Lind, L., Giedraitis, V., Perola, M., Evans, A., Ferrieres, J., Virtamo, J., Kee, F., Tregouet, D-A., Arveiler, D., Amouyel, P., Gianfagna, F., Brambilla, P., Ripatti, S., van Duijn, C. M., Metspalu, A., Prokopenko, I., McCarthy, M. I., Pedersen, N. L., Ingelsson, E. & European Network Genetic Genomic E, Apr 2015, In : International Journal of Epidemiology. 44, 2, p. 578-586 9 p.

Research output: Contribution to journalArticleScientificpeer-review

A fast universal self-tuned sampler within Gibbs sampling

Martino, L., Yang, H., Luengo, D., Kanniainen, J. & Corander, J., Dec 2015, In : Digital Signal Processing. 47, p. 68-83 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors

Fall, T., Hagg, S., Ploner, A., Maegi, R., Fischer, K., Draisma, H. H. M., Sarin, A-P., Benyamin, B., Ladenvall, C., Akerlund, M., Kals, M., Esko, T., Nelson, C. P., Kaakinen, M., Huikari, V., Mangino, M., Meirhaeghe, A., Kristiansson, K., Nuotio, M-L., Kobl, M. & 31 othersGrallert, H., Dehghan, A., Kuningas, M., de Vries, P. S., de Bruijn, R. F. A. G., Willems, S. M., Heikkila, K., Silventoinen, K., Pietilainen, K. H., Legry, V., Giedraitis, V., Goumidi, L., Syvanen, A-C., Strauch, K., Koenig, W., Lichtner, P., Herder, C., Palotie, A., Menni, C., Uitterlinden, A. G., Kuulasmaa, K., Havulinna, A. S., Moreno, L. A., Gonzalez-Gross, M., Evans, A., Tregouet, D-A., Perola, M., Kaprio, J., Groop, L., Ripatti, S. & ENGAGE Consortium, May 2015, In : Diabetes. 64, 5, p. 1841-1852 12 p.

Research output: Contribution to journalArticleScientificpeer-review

A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism

Loukola, A., Buchwald, J., Gupta, R., Palviainen, T., Hallfors, J., Tikkanen, E., Korhonen, T., Ollikainen, M., Sarin, A-P., Ripatti, S., Lehtimaki, T., Raitakari, O., Salomaa, V., Rose, R. J., Tyndale, R. F. & Kaprio, J., Sep 2015, In : PLoS Genetics. 11, 9, 23 p., 1005498.

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An Adaptive Population Importance Sampler: Learning From Uncertainty

Martino, L., Elvira, V., Luengo, D. & Corander, J., 15 Aug 2015, In : IEEE Transactions on Signal Processing. 63, 16, p. 4422-4437 16 p.

Research output: Contribution to journalArticleScientificpeer-review

ARK: Aggregation of Reads by K-Means for Estimation of Bacterial Community Composition

Koslicki, D., Chatterjee, S., Shahrivar, D., Walker, A. W., Francis, S. C., Fraser, L. J., Vehkaperae, M., Lan, Y. & Corander, J., 23 Oct 2015, In : PLoS One. 10, 10, 16 p., 0140644.

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Assessing allele-specific expression across multiple tissues from RNA-seq read data

Pirinen, M., Lappalainen, T., Zaitlen, N. A., Dermitzakis, E. T., Donnelly, P., McCarthy, M. I., Rivas, M. A. & GTEx Consortium, 1 Aug 2015, In : Bioinformatics. 31, 15, p. 2497-2504 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Baseline adjustment increases accurate interpretation of posturographic sway scores

Tietavainen, A., Corander, J. & Haeggstrom, E., Sep 2015, In : Gait & Posture. 42, 3, p. 285-288 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Cell Specific eQTL Analysis without Sorting Cells

Westra, H-J., Arends, D., Esko, T., Peters, M. J., Schurmann, C., Schramm, K., Kettunen, J., Yaghootkar, H., Fairfax, B. P., Andiappan, A. K., Li, Y., Fu, J., Karjalainen, J., Platteel, M., Visschedijk, M., Weersma, R. K., Kasela, S., Milani, L., Tserel, L., Peterson, P. & 38 othersReinmaa, E., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Homuth, G., Petersmann, A., Lorbeer, R., Prokisch, H., Meitinger, T., Herder, C., Roden, M., Grallert, H., Ripatti, S., Perola, M., Wood, A. R., Melzer, D., Ferrucci, L., Singleton, A. B., Hernandez, D. G., Knight, J. C., Melchiotti, R., Lee, B., Poidinger, M., Zolezzi, F., Larbi, A., Wang, D. Y., van den Berg, L. H., Veldink, J. H., Rotzschke, O., Makino, S., Salomaa, V., Strauch, K., Voelker, U., van Meurs, J. B. J., Metspalu, A., Wijmenga, C., Jansen, R. C. & Franke, L., May 2015, In : PLoS Genetics. 11, 5, 17 p., 1005223.

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Climate induces seasonality in pneumococcal transmission

Numminen, E., Chewapreecha, C., Turner, C., Goldblatt, D., Nosten, F., Bentley, S. D., Turner, P. & Corander, J., 12 Jun 2015, In : Scientific Reports. 5, 14 p., 11344.

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Core Genome Multilocus Sequence Typing Scheme for High-Resolution Typing of Enterococcus faecium

de Been, M., Pinholt, M., Top, J., Bletz, S., Mellmann, A., van Schaik, W., Brouwer, E., Rogers, M., Kraat, Y., Bonten, M., Corander, J., Westh, H., Harmsen, D. & Willems, R. J. L., Dec 2015, In : Journal of Clinical Microbiology. 53, 12, p. 3788-3797 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

Horikoshi, M., Maegi, R., van de Bunt, M., Surakka, I., Sarin, A-P., Mahajan, A., Marullo, L., Thorleifsson, G., Haegg, S., Hottenga, J-J., Ladenvall, C., Ried, J. S., Winkler, T. W., Willems, S. M., Tsernikova, N., Esko, T., Beekman, M., Nelson, C. P., Willenborg, C., Wiltshire, S. & 31 othersFerreira, T., Fernandez, J., Gaulton, K. J., Steinthorsdottir, V., Hamsten, A., Magnusson, P. K. E., Willemsen, G., Milaneschi, Y., Robertson, N. R., Groves, C. J., Bennett, A. J., Lehtimaeki, T., Viikari, J. S., Rung, J., Lyssenko, V., Perola, M., Heid, I. M., Herder, C., Grallert, H., Mueller-Nurasyid, M., Roden, M., Hypponen, E., Isaacs, A., van Leeuwen, E. M., Karssen, L. C., Mihailov, E., Kaprio, J., Eriksson, J. G., Groop, L., Ripatti, S. & Engage Consortium, Jul 2015, In : PLoS Genetics. 11, 7, 24 p., 1005230.

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Ecological Overlap and Horizontal Gene Transfer in Staphylococcus aureus and Staphylococcus epidermidis

Meric, G., Miragaia, M., de Been, M., Yahara, K., Pascoe, B., Mageiros, L., Mikhail, J., Harris, L. G., Wilkinson, T. S., Rolo, J., Lamble, S., Bray, J. E., Jolley, K. A., Hanage, W. P., Bowden, R., Maiden, M. C. J., Mack, D., de Lencastre, H., Feil, E. J., Corander, J. & 1 othersSheppard, S. K., May 2015, In : Genome Biology and Evolution. 7, 5, p. 1313-1328 16 p.

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Effect of predicted protein-truncating genetic variants on the human transcriptome

Rivas, M. A., Pirinen, M., Conrad, D. F., Lek, M., Tsang, E. K., Karczewski, K. J., Maller, J. B., Kukurba, K. R., DeLuca, D. S., Fromer, M., Ferreira, P. G., Smith, K. S., Zhang, R., Zhao, F., Banks, E., Poplin, R., Ruderfer, D. M., Purcell, S. M., Tukiainen, T., Minikel, E. V. & 19 othersStenson, P. D., Cooper, D. N., Huang, K. H., Sullivan, T. J., Nedzel, J., Bustamante, C. D., Li, J. B., Daly, M. J., Guigo, R., Donnelly, P., Ardlie, K., Sammeth, M., Dermitzakis, E. T., McCarthy, M. I., Montgomery, S. B., Lappalainen, T., MacArthur, D. G., GTEx Consortium & Geuvadis Consortium, 8 May 2015, In : Science. 348, 6235, p. 666-669 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Fast and accurate approximate inference of transcript expression from RNA-seq data

Hensman, J., Papastamoulis, P., Glaus, P., Honkela, A. J. H. & Rattray, M., 15 Dec 2015, In : Bioinformatics. 31, 24, p. 3881-3889 9 p.

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Gaussian process test for high-throughput sequencing time series: application to experimental evolution

Topa, H., Jonas, A., Kofler, R., Kosiol, C. & Honkela, A., 1 Jun 2015, In : Bioinformatics. 31, 11, p. 1762-1770 9 p.

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Gene Loss and Lineage-Specific Restriction-Modification Systems Associated with Niche Differentiation in the Campylobacter jejuni Sequence Type 403 Clonal Complex

Morley, L., McNally, A., Paszkiewicz, K., Corander, J., Meric, G., Sheppard, S. K., Blom, J. & Manning, G., Jun 2015, In : Applied and Environmental Microbiology. 81, 11, p. 3641-3647 7 p.

Research output: Contribution to journalArticleScientificpeer-review

General state-space population dynamics model for Bayesian stock assessment

Mäntyniemi, S. H. P., Whitlock, R. E., Perälä, T. A., Blomstedt, P. A., Vanhatalo, J. P., Rincón, M. M., Kuparinen, A. K., Pulkkinen, H. P. & Kuikka, O. S., 7 Aug 2015, In : ICES Journal of Marine Science. 72, 8, p. 2209-2222 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetically Determined Height and Coronary Artery Disease

Nelson, C. P., Hamby, S. E., Saleheen, D., Hopewell, J. C., Zeng, L., Assimes, T. L., Kanoni, S., Willenborg, C., Burgess, S., Amouyel, P., Anand, S., Blankenberg, S., Boehm, B. O., Clarke, R. J., Collins, R., Dedoussis, G., Farrall, M., Franks, P. W., Groop, L., Hall, A. S. & 31 othersHamsten, A., Hengstenberg, C., Hovingh, G. K., Ingelsson, E., Kathiresan, S., Kee, F., Koenig, I. R., Kooner, J., Lehtimaeki, T., Maerz, W., McPherson, R., Metspalu, A., Nieminen, M. S., O'Donnell, C. J., Palmer, C. N. A., Peters, A., Perola, M., Reilly, M. P., Ripatti, S., Roberts, R., Salomaa, V., Shah, S. H., Schreiber, S., Siegbahn, A., Thorsteinsdottir, U., Veronesi, G., Wareham, N., Willer, C. J., Zalloua, P. A., CARDIoGRAM C4D Consortium & Lokki, ML., 23 Apr 2015, In : New England Journal of Medicine. 372, 17, p. 1608-1618 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Gaulton, K. J., Ferreira, T., Lee, Y., Raimondo, A., Maegi, R., Reschen, M. E., Mahajan, A., Locke, A., Rayner, N. W., Robertson, N., Scott, R. A., Prokopenko, I., Scott, L. J., Green, T., Sparso, T., Thuillier, D., Yengo, L., Grallert, H., Wahl, S., Franberg, M. & 199 othersStrawbridge, R. J., Kestler, H., Chheda, H., Eisele, L., Gustafsson, S., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Karssen, L. C., van Leeuwen, E. M., Willems, S. M., Li, M., Chen, H., Fuchsberger, C., Kwan, P., Ma, C., Linderman, M., Lu, Y., Thomsen, S. K., Rundle, J. K., Beer, N. L., van de Bunt, M., Chalisey, A., Kang, H. M., Voight, B. F., Abecasis, G. R., Almgren, P., Baldassarre, D., Balkau, B., Benediktsson, R., Blueher, M., Boeing, H., Bonnycastle, L. L., Bottinger, E. P., Burtt, N. P., Carey, J., Charpentier, G., Chines, P. S., Cornelis, M. C., Couper, D. J., Crenshaw, A. T., van Dam, R. M., Doney, A. S. F., Dorkhan, M., Edkins, S., Eriksson, J. G., Esko, T., Eury, E., Fadista, J., Flannick, J., Fontanillas, P., Fox, C., Franks, P. W., Gertow, K., Gieger, C., Gigante, B., Gottesman, O., Grant, G. B., Grarup, N., Groves, C. J., Hassinen, M., Have, C. T., Herder, C., Holmen, O. L., Hreidarsson, A. B., Humphries, S. E., Hunter, D. J., Jackson, A. U., Jonsson, A., Jorgensen, M. E., Jorgensen, T., Kao, W-H. L., Kerrison, N. D., Kinnunen, L., Klopp, N., Kong, A., Kovacs, P., Kraft, P., Kravic, J., Langford, C., Leander, K., Liang, L., Lichtner, P., Lindgren, C. M., Lindholm, E., Linneberg, A., Liu, C-T., Lobbens, S., Luan, J., Lyssenko, V., Mannisto, S., McLeod, O., Meyer, J., Mihailov, E., Mirza, G., Muehleisen, T. W., Mueller-Nurasyid, M., Navarro, C., Noethen, M. M., Oskolkov, N. N., Owen, K. R., Palli, D., Pechlivanis, S., Peltonen, L., Perry, J. R. B., Platou, C. G. P., Roden, M., Ruderfer, D., Rybin, D., van der Schouw, Y. T., Sennblad, B., Sigurdsson, G., Stancakova, A., Steinbach, G., Storm, P., Strauch, K., Stringham, H. M., Sun, Q., Thorand, B., Tikkanen, E., Tonjes, A., Trakalo, J., Tremoli, E., Tuomi, T., Wennauer, R., Wiltshire, S., Wood, A. R., Zeggini, E., Dunham, I., Birney, E., Pasquali, L., Ferrer, J., Loos, R. J. F., Dupuis, J., Florez, J. C., Boerwinkle, E., Pankow, J. S., van Duijn, C., Sijbrands, E., Meigs, J. B., Hu, F. B., Thorsteinsdottir, U., Stefansson, K., Lakka, T. A., Rauramaa, R., Stumvoll, M., Pedersen, N. L., Lind, L., Keinanen-Kiukaanniemi, S. M., Korpi-Hyovalti, E., Saaristo, T. E., Saltevo, J., Kuusisto, J., Laakso, M., Metspalu, A., Erbel, R., Joecke, K-H., Moebus, S., Ripatti, S., Salomaa, V., Ingelsson, E., Boehm, B. O., Bergman, R. N., Collins, F. S., Mohlke, K. L., Koistinen, H., Tuomilehto, J., Hveem, K., Njolstad, I., Deloukas, P., Donnelly, P. J., Frayling, T. M., Hattersley, A. T., de Faire, U., Hamsten, A., Illig, T., Peters, A., Cauchi, S., Sladek, R., Froguel, P., Hansen, T., Pedersen, O., Morris, A. D., Palmer, C. N. A., Kathiresan, S., Melander, O., Nilsson, P. M., Groop, L. C., Barroso, I., Langenberg, C., Wareham, N. J., O'Callaghan, C. A., Gloyn, A. L., Altshuler, D., Boehnke, M., Teslovich, T. M., McCarthy, M. I., Morris, A. P. & DIAbet Genetics Replication Meta-A, Dec 2015, In : Nature Genetics. 47, 12, p. 1415-1425 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic import and phenotype specific alleles associated with hyper-invasion in Campylobacter jejuni

Baig, A., McNally, A., Dunn, S., Paszkiewicz, K. H., Corander, J. & Manning, G., 24 Oct 2015, In : BMC Genomics. 16, 12 p., 852.

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Genetic Loci Associated with Allergic Sensitization in Lithuanians

Sauliene, I., Greiciuviene, J., Sukiene, L., Juskeviciute, N., Benner, C., Zinkeviciene, A., Ripatti, S., Donner, K. & Kainov, D., 27 Jul 2015, In : PLoS One. 10, 7, 7 p., 0134188.

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Genetic studies of body mass index yield new insights for obesity biology

Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., Powell, C., Vedantam, S., Buchkovich, M. L., Yang, J., Croteau-Chonka, D. C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z., Luan, J., Maegi, R., Randall, J. C., Winkler, T. W. & 44 othersWood, A. R., Workalemahu, T., Faul, J. D., Smith, J. A., Zhao, J. H., Zhao, W., Chen, J., Fehrmann, R., Hedman, A. K., Karjalainen, J., Schmidt, E. M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bolton, J. L., Bragg-Gresham, L., Eklund, N., Koskenvuo, M., Sandholm, N., Eriksson, J. G., Jousilahti, P., Kaprio, J., Sinisalo, J., Groop, L. C., Kivimaki, M., Perola, M., Tuomilehto, J., LifeLines Cohort Study, ADIPOGen Consortium, AGEN-BMI Working Grp, CARDIOGRAMplusC4D Consortium, CKDGen Consortium, GLGC, ICBP, MAGIC Investigators, MuTHER Consortium, MIGen Consortium, PAGE Consortium, ReproGen Consortium, GENIE Consortium, Int Endogene Consortium, Lokki, M-L. & Ripatti, S. O., 12 Feb 2015, In : Nature. 518, 7538, p. 197-U401 23 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic Variants on Chromosome 1p13.3 Are Associated with Non-ST Elevation Myocardial Infarction and the Expression of DRAM2 in the Finnish Population

Salo, P. P., Vaara, S., Kettunen, J., Pirinen, M., Sarin, A-P., Huikuri, H., Karhunen, P. J., Eskola, M., Nikus, K., Lokki, M-L., Ripatti, S., Havulinna, A. S., Salomaa, V., Palotie, A., Nieminen, M. S., Sinisalo, J. & Perola, M., 28 Oct 2015, In : PLoS One. 10, 10, 16 p., 0140576.

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Genome-Wide Analysis of Evolutionary Markers of Human Influenza A(H1N1)pdm09 and A(H3N2) Viruses May Guide Selection of Vaccine Strain Candidates

Belanov, S. S., Bychkov, D., Benner, C., Ripatti, S., Ojala, T., Kankainen, M., Lee, H. K., Tang, J. W-T. & Kainov, D. E., Dec 2015, In : Genome Biology and Evolution. 7, 12, p. 3472-3483 12 p.

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Genome-wide modeling of transcription kinetics reveals patterns of RNA production delays

Honkela, A., Peltonen, J., Topa, H., Charapitsa, I., Matarese, F., Grote, K., Stunnenberg, H. G., Reid, G., Lawrence, N. D. & Rattray, M., 20 Oct 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 42, p. 13115-13120 6 p.

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Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis

Weinert, L. A., Chaudhuri, R. R., Wang, J., Peters, S. E., Corander, J., Jombart, T., Baig, A., Howell, K. J., Vehkala, M., Valimaki, N., Harris, D., Tran Thi Bich Chieu, Nguyen Van Vinh Chau, Campbell, J., Schultsz, C., Parkhill, J., Bentley, S. D., Langford, P. R., Rycroft, A. N., Wren, B. W. & 7 othersFarrar, J., Baker, S., Ngo Thi Hoa, Holden, M. T. G., Tucker, A. W., Maskell, D. J. & BRaDP1T Consortium, Mar 2015, In : Nature Communications. 6, 9 p., 6740.

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Hierarchical Bayesian Model for Rare Variant Association Analysis Integrating Genotype Uncertainty in Human Sequence Data

He, L., Pitkaniemi, J., Sarin, A-P., Salomaa, V., Sillanpaa, M. J. & Ripatti, S., Feb 2015, In : Genetic Epidemiology. 39, 2, p. 89-100 12 p.

Research output: Contribution to journalArticleScientificpeer-review

K-Pax2: Bayesian identification of cluster-defining amino acid positions in large sequence datasets

Pessia, A., Grad, Y., Cobey, S., Puranen, J. S. & Corander, J., 15 Jul 2015, In : Microbial Genomics. 1, 1, 11 p.

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Labeled directed acyclic graphs: a generalization of context-specific independence in directed graphical models

Pensar, J., Nyman, H., Koski, T. & Corander, J., Mar 2015, In : Data Mining and Knowledge Discovery. 29, 2, p. 503-533 31 p.

Research output: Contribution to journalArticleScientificpeer-review

Metabolite Profiling and Cardiovascular Event Risk A Prospective Study of 3 Population-Based Cohorts

Wurtz, P., Havulinna, A. S., Soininen, P., Tynkkynen, T., Prieto-Merino, D., Tillin, T., Ghorbani, A., Artati, A., Wang, Q., Tiainen, M., Kangas, A. J., Kettunen, J., Kaikkonen, J., Mikkila, V., Jula, A., Kahonen, M., Lehtimaki, T., Lawlor, D. A., Gaunt, T. R., Hughes, A. D. & 13 othersSattar, N., Illig, T., Adamski, J., Wang, T. J., Perola, M., Ripatti, S., Vasan, R. S., Raitakari, O. T., Gerszten, R. E., Casas, J-P., Chaturvedi, N., Ala-Korpela, M. & Salomaa, V., 3 Mar 2015, In : Circulation . 131, 9, p. 774-U52 37 p.

Research output: Contribution to journalArticleScientificpeer-review

Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans

Huffman, J. E., Albrecht, E., Teumer, A., Mangino, M., Kapur, K., Johnson, T., Kutalik, Z., Pirastu, N., Pistis, G., Lopez, L. M., Haller, T., Salo, P., Goel, A., Li, M., Tanaka, T., Dehghan, A., Ruggiero, D., Malerba, G., Smith, A. V., Nolte, I. M. & 100 othersPortas, L., Phipps-Green, A., Boteva, L., Navarro, P., Johansson, A., Hicks, A. A., Polasek, O., Esko, T., Peden, J. F., Harris, S. E., Murgia, F., Wild, S. H., Tenesa, A., Tin, A., Mihailov, E., Grotevendt, A., Gislason, G. K., Coresh, J., D'Adamo, P., Ulivi, S., Vollenweider, P., Waeber, G., Campbell, S., Kolcic, I., Fisher, K., Viigimaa, M., Metter, J. E., Masciullo, C., Trabetti, E., Bombieri, C., Sorice, R., Doering, A., Reischl, E., Strauch, K., Hofman, A., Uitterlinden, A. G., Waldenberger, M., Wichmann, H-E., Davies, G., Gow, A. J., Dalbeth, N., Stamp, L., Smit, J. H., Kirin, M., Nagaraja, R., Nauck, M., Schurmann, C., Budde, K., Farrington, S. M., Theodoratou, E., Jula, A., Salomaa, V., Sala, C., Hengstenberg, C., Burnier, M., Maegi, R., Klopp, N., Kloiber, S., Schipf, S., Ripatti, S., Cabras, S., Soranzo, N., Homuth, G., Nutile, T., Munroe, P. B., Hastie, N., Campbell, H., Rudan, I., Cabrera, C., Haley, C., Franco, O. H., Merriman, T. R., Gudnason, V., Pirastu, M., Penninx, B. W., Snieder, H., Metspalu, A., Ciullo, M., Pramstaller, P. P., van Duijn, C. M., Ferrucci, L., Gambaro, G., Deary, I. J., Dunlop, M. G., Wilson, J. F., Gasparini, P., Gyllensten, U., Spector, T. D., Wright, A. F., Hayward, C., Watkins, H., Perola, M., Bochud, M., Kao, W. H. L., Caulfield, M., Toniolo, D., Voelzke, H., Gieger, C., Koettgen, A. & Vitart, V., 26 Mar 2015, In : PLoS One. 10, 3, 21 p., 0119752.

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Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe

Mattila, J., Havula, E., Suominen, E., Teesalu, M., Surakka, I., Hynynen, R., Kilpinen, H., Vaananen, J., Hovatta, I., Kakela, R., Ripatti, S., Sandmann, T. & Hietakangas, V., 13 Oct 2015, In : Cell Reports. 13, 2, p. 350-364 15 p.

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New genetic loci link adipose and insulin biology to body fat distribution

Shungin, D., Winkler, T. W., Croteau-Chonka, D. C., Ferreira, T., Lockes, A. E., Maegi, R., Strawbridge, R. J., Pers, T. H., Fischer, K., Justice, A. E., Workalemahu, T., Wu, J. M. W., Buchkovich, M. L., Heard-Costa, N. L., Roman, T. S., Drong, A. W., Song, C., Gustafsson, S., Day, F. R., Esko, T. & 401 othersFall, T., Kutalik, Z., Luan, J., Randall, J. C., Scherag, A., Vedantam, S., Wood, A. R., Chen, J., Fehrmann, R., Karjalainen, J., Kahali, B., Liu, C-T., Schmidt, E. M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bragg-Gresham, J. L., Buyske, S., Demirkan, A., Ehret, G. B., Feitosa, M. F., Goel, A., Jackson, A. U., Johnson, T., Kleber, M. E., Kristiansson, K., Mangino, M., Leach, I. M., Medina-Gomez, C., Palmer, C. D., Pasko, D., Pechlivaniss, S., Peters, M. J., Prokopenko, I., Stancakova, A., Sung, Y. J., Tanakam, T., Teumer, A., Van Vliet-Ostaptchouk, J. V., Yengo, L., Zhang, W., Albrecht, E., Arnlov, J., Arscott, G. M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A. J., Berne, C., Blueher, M., Buhringer, S., Bonnet, F., Boettcher, Y., Bruinenberg, M., Carba, D. B., Caspersen, I. H., Clarke, R., Daw, E. W., Deelen, J., Deelman, E., Delgado, G., Doney, A. S. F., Eklund, N., Erdos, M. R., Estrada, K., Eury, E., Friedrichs, N., Garcia, M. E., Giedraitis, V., Gigante, B., Go, A. S., Golay, A., Grallert, H., Grammer, T. B., Graessler, J., Grewal, J., Groves, C. J., Haller, T., Hallmans, G., Hartman, C. A., Hassinen, M., Hayward, C., Heikkila, K., Herzig, K-H., Helmer, Q., Hillege, H. L., Holmen, O., Hunt, S. C., Isaacs, A., Ittermann, T., James, A. L., Johansson, I., Juliusdottir, T., Kalafati, I-P., Kinnunen, L., Koenig, W., Kooner, I. K., Kratzer, W., Lamina, C., Leander, K., Lee, N. R., Lichtner, P., Lind, L., Lindstrom, J., Lobbens, S., Lorentzon, M., Mach, F., Magnusson, P. K. E., Mahajan, A., McArdle, W. L., Menni, C., Merger, S., Mihailov, E., Milani, L., Mills, R., Moayyeri, A., Monda, K. L., Mooijaart, S. P., Muehleisen, T. W., Mulas, A., Mueller, G., Mueller-Nurasyid, M., Nagaraja, R., Nalls, M. A., Narisu, N., Glorioso, N., Nolte, I. M., Olden, M., Rayner, N. W., Renstrom, F., Ried, J. S., Robertson, N. R., Rose, L. M., Sanna, S., Scharnagl, H., Scholtens, S., Sennblad, B., Seufferlein, T., Sitlani, C. M., Smith, A. V., Stirrups, K., Stringham, H. M., Sundstrom, J., Swertz, M. A., Swift, A. J., Syvanen, A-C., Tayo, B. O., Thorand, B., Thorleifsson, G., Tomaschitz, A., Troffa, C., van Oort, F. V. A., Verweij, N., Vonk, J. M., Waite, L. L., Wennauer, R., Wilsgaard, T., Wojczynski, M. K., Wong, A., Zhang, Q., Zhao, J. H., Brennan, E. P., Choi, M., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Gharavi, A. G., Hedman, A. K., Hivert, M-F., Huang, J., Kanoni, S., Karpe, F., Keildson, S., Kiryluk, K., Liang, L., Lifton, R. P., Ma, B., McKnight, A. J., McPherson, R., Metspalu, A., Min, J. L., Moffatt, M. F., Montgomery, G. W., Murabito, J. M., Nicholson, G., Nyholt, D. R., Olsson, C., Perry, J. R. B., Reinmaa, E., Salem, R. M., Sandholm, N., Schadt, E. E., Scott, R. A., Stolk, L., Vallejo, E. E., Westra, H-J., Zondervan, K. T., Amouyel, P., Arveiler, D., Bakker, S. J. L., Beilby, J., Bergman, R. N., Blangero, J., Brown, M. J., Burnier, M., Campbell, H., Chakravarti, A., Chiness, P. S., Claudi-Boehmi, S., Collins, F. S., Crawford, D. C., Danesh, J., de Faire, U., de Geusl, E. J. C., Doerr, M., Erbel, R., Eriksson, J. G., Farrall, M., Ferrannini, E., Ferrieres, J., Forouhi, N. G., Forrester, T., Franco, O. H., Gansevoort, R. T., Gieger, C., Gudnason, V., Haiman, C. A., Harris, T. B., Hattersley, A. T., Heliovaara, M., Hicks, A. A., Hingorani, A. D., Hoffmann, W., Hofman, A., Homuth, G., Humphries, S. E., Hyppoenen, E., Illig, T., Jarvelin, M-R., Johansen, B., Jousilahti, P., Jula, A. M., Kaprio, J., Kee, F., Keinanen-Kiukaanniemi, S. M., Kooner, J. S., Kooperberg, C., Kovacs, P., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Lakka, T. A., Langenberg, C., Le Marchand, L., Lehtimaki, T., Lyssenko, V., Mannisto, S., Marette, A., Matise, T. C., McKenzie, C. A., McKnight, B., Musk, A. W., Mohlenkamp, S., Morris, A. D., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Palmer, L. J., Penninx, B. W., Peters, A., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ridker, P. M., Ritchie, M. D., Rudan, I., Salomaa, V., Samani, N. J., Saramies, J., Sarzynski, M. A., Schwarz, P. E. H., Shuldiner, A. R., Staessen, J. A., Steinthorsdottir, V., Stolk, R. P., Strauch, K., Toenjes, A., Tremblay, A., Tremoli, E., Vohl, M-C., Voelker, U., Vollenweider, P., Wilson, J. F., Witteman, J. C., Adair, L. S., Bochud, M., Boehm, B. O., Bornstein, S. R., Bouchard, C., Cauchi, S., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Cooper, R. S., Dedoussis, G., Ferrucci, L., Froguel, P., Grabe, H-J., Hamsten, A., Hui, J., Hveem, K., Joeckel, K-H., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Maerz, W., Munroe, P. B., Njolstad, I., Oostra, B. A., Palmer, C. N. A., Pedersen, N. L., Perola, M., Perusse, L., Peters, U., Power, C., Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T. E., Saleheen, D., Sinisalo, J., Slagboom, P. E., Snieder, H., Spector, T. D., Thorsteinsdottir, U. R., Stumvoll, M., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., van der Harst, P., Veronesi, G., Walker, M., Wareham, N. J., Watkins, H., Wichmann, H-E., Abecasis, G. R., Assimes, T. L., Berndt, S. I., Boehnkes, M., Borecki, I. B., Deloukas, P., Franke, L., Frayling, T. M., Groop, L. C., Hunter, D. J., Kaplan, R. C., O'Connell, J. R., Qi, L., Schlessinger, D., Strachan, D. P., Stefansson, K., van Dujin, C. M., Willer, C. J., Visscher, P. M., Yang, J., Hirschhorn, J. N., Zillikens, M. C., McCarthy, M. I., Speliotes, E. K., North, K. E., Fox, C. S., Barroso, I., Franks, P. W., Ingelsson, E., Heid, I. M., Loos, R. J. F., Cupples, L. A., Morris, A. P., Lindgren, C. M., Mohlke, K. L., ADIPOGEN Consortium, CARDIOGRAMplusC4D Consortium, CKDGen Consortium, GEFOS Consortium, GENIE Consortium, GLGC, ICBP, Int Endogene Consortium, LifeLines Cohort Study, MAGIC Investigators, MuTHER Consortium, PAGE Consortium, ReproGen Consortium, Lokki, M-L. & Ripatti, S. O., 12 Feb 2015, In : Nature. 518, 7538, p. 187-U378 22 p.

Research output: Contribution to journalArticleScientificpeer-review

Novel R Pipeline for Analyzing Biolog Phenotypic Microarray Data

Vehkala, M., Shubin, M., Connor, T. R., Thomson, N. R. & Corander, J., 18 Mar 2015, In : PLoS One. 10, 3, p. 1-14 14 p., 0118392.

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Novel staphylococcal species that form part of a Staphylococcus aureus-related complex: the non-pigmented Staphylococcus argenteus sp nov and the non-human primate-associated Staphylococcus schweitzeri sp nov.

Tong, S. Y. C., Schaumburg, F., Ellington, M. J., Corander, J., Pichon, B., Leendertz, F., Bentley, S. D., Parkhill, J., Holt, D. C., Peters, G. & Giffard, P. M., Jan 2015, In : International Journal of Systematic and Evolutionary Microbiology. 65, p. 15-22 8 p.

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On the Outage Capacity of Orthogonal Space-Time Block Codes Over Multi-Cluster Scattering MIMO Channels

Wei, L., Zheng, Z., Corander, J. & Taricco, G., May 2015, In : IEEE Transactions on Communications. 63, 5, p. 1700-1711 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Patterns of genome evolution that have accompanied host adaptation in Salmonella

Langridge, G. C., Fookes, M., Connor, T. R., Feltwell, T., Feasey, N., Parsons, B. N., Seth-Smith, H. M. B., Barquist, L., Stedman, A., Humphrey, T., Wigley, P., Peters, S. E., Maskell, D. J., Corander, J., Chabalgoity, J. A., Barrow, P., Parkhill, J., Dougan, G. & Thomson, N. R., 20 Jan 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 3, p. 863-868 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Pharmacogenomics of Hypertension: A Genome-Wide, Placebo-Controlled Cross-Over Study, Using Four Classes of Antihypertensive Drugs

Hiltunen, T. P., Donner, K. M., Sarin, A-P., Saarela, J., Ripatti, S., Chapman, A. B., Gums, J. G., Gong, Y., Cooper-DeHoff, R. M., Frau, F., Glorioso, V., Zaninello, R., Salvi, E., Glorioso, N., Boerwinkle, E., Turner, S. T., Johnson, J. A. & Kontula, K. K., Jan 2015, In : Journal of the American Heart Association. 4, 1, 26 p., 001521.

Research output: Contribution to journalArticleScientificpeer-review