Publications 2001 2020

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2015

Pharmacogenomics of Hypertension: A Genome-Wide, Placebo-Controlled Cross-Over Study, Using Four Classes of Antihypertensive Drugs

Hiltunen, T. P., Donner, K. M., Sarin, A-P., Saarela, J., Ripatti, S., Chapman, A. B., Gums, J. G., Gong, Y., Cooper-DeHoff, R. M., Frau, F., Glorioso, V., Zaninello, R., Salvi, E., Glorioso, N., Boerwinkle, E., Turner, S. T., Johnson, J. A. & Kontula, K. K., Jan 2015, In : Journal of the American Heart Association. 4, 1, 26 p., 001521.

Research output: Contribution to journalArticleScientificpeer-review

Population Biology of Intestinal Enterococcus Isolates from Hospitalized and Nonhospitalized Individuals in Different Age Groups

Tedim, A. P., Ruiz-Garbajosa, P., Corander, J., Rodriguez, C. M., Canton, R., Willems, R. J., Baquero, F. & Coque, T. M., Mar 2015, In : Applied and Environmental Microbiology. 81, 5, p. 1820–1831 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Posterior Predictive Comparisons for the Two-sample Problem

Blomstedt, P. & Corander, J., 2015, In : Communications in Statistics: Theory and Methods. 44, 2, p. 376-389 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Probe Region Expression Estimation for RNA-Seq Data for Improved Microarray Comparability

Uziela, K. & Honkela, A., 12 May 2015, In : PLoS One. 10, 5, 18 p., 0126545.

Research output: Contribution to journalArticleScientificpeer-review

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Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection

Darch, S. E., McNally, A., Harrison, F., Corander, J., Barr, H. L., Paszkiewicz, K., Holden, S., Fogarty, A., Crusz, S. A. & Diggle, S. P., 12 Jan 2015, In : Scientific Reports. 5, 12 p., 7649.

Research output: Contribution to journalArticleScientificpeer-review

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Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

Artigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., Shrine, N., Obeidat, M., Trochet, H., McArdle, W. L., Alves, A. C., Hui, J., Zhao, J. H., Joshi, P. K., Teumer, A., Albrecht, E., Imboden, M., Rawal, R., Lopez, L. M., Marten, J. & 31 others, Enroth, S., Surakka, I., Polasek, O., Lyytikainen, L-P., Granell, R., Hysi, P. G., Flexeder, C., Mahajan, A., Beilby, J., Bosse, Y., Brandsma, C-A., Campbell, H., Gieger, C., Glaeser, S., Gonzalez, J. R., Grallert, H., Hammond, C. J., Harris, S. E., Hartikainen, A-L., Heliovaara, M., Henderson, J., Hocking, L., Horikoshi, M., Hutri-Kahonen, N., Ingelsson, E., Johansson, A., Kemp, J. P., Kolcic, I., Kumar, A., Ripatti, S. & UK BiLEVE, Dec 2015, In : Nature Communications. 6, 12 p., 8658.

Research output: Contribution to journalArticleScientificpeer-review

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Targeted Resequencing of the Pericentromere of Chromosome 2 Linked to Constitutional Delay of Growth and Puberty

Cousminer, D. L., Leinonen, J. T., Sarin, A-P., Chheda, H., Surakka, I., Wehkalampi, K., Ellonen, P., Ripatti, S., Dunkel, L., Palotie, A. & Widen, E., 1 Jun 2015, In : PLoS One. 10, 6, 16 p., 0128524.

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The Biomarker GlycA is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

Ritchie, S. C., Würtz, P., Nath, A. P., Abraham, G., Havulinna, A. S., Fearnley, L. G., Sarin, A-P., Kangas, A. J., Soininen, P., Aalto, K., Seppälä, I., Raitoharju, E., Salmi, M., Maksimow, M., Männistö, S., Kähönen, M., Juonala, M., Ripatti, S., Lehtimäki, T., Jalkanen, S. & 6 others, Perola, M., Raitakari, O., Salomaa, V., Ala-Korpela, M., Kettunen, J. & Inouye, M., 2015, In : Cell Systems. 1, 4, p. 293-301 9 p.

Research output: Contribution to journalArticleScientificpeer-review

The fine-scale genetic structure of the British population

Leslie, S., Winney, B., Hellenthal, G., Davison, D., Boumertit, A., Day, T., Hutnik, K., Royrvik, E. C., Cunliffe, B., Lawson, D. J., Falush, D., Freeman, C., Pirinen, M., Myers, S., Robinson, M., Donnelly, P., Bodmer, W., Wellcome Trust Case Control & Int Multiple Sclerosis Genetics, 19 Mar 2015, In : Nature. 519, 7543, p. 309-+ 24 p.

Research output: Contribution to journalArticleScientificpeer-review

The impact of low-frequency and rare variants on lipid levels

Surakka, I., Horikoshi, M., Magi, R., Sarin, A-P., Mahajan, A., Lagou, V., Marullo, L., Ferreira, T., Miraglio, B., Timonen, S., Kettunen, J., Pirinen, M., Karjalainen, J., Thorleifsson, G., Hagg, S., Hottenga, J-J., Isaacs, A., Ladenvall, C., Beekman, M., Esko, T. & 31 others, Ried, J. S., Nelson, C. P., Willenborg, C., Gustafsson, S., Westra, H-J., Blades, M., de Craen, A. J. M., de Geus, E. J., Deelen, J., Grallert, H., Hamsten, A., Havulinna, A. S., Hengstenberg, C., Houwing-Duistermaat, J. J., Hypponen, E., Karssen, L. C., Lehtimaki, T., Lyssenko, V., Magnusson, P. K. E., Mihailov, E., Mpindi, J-P., Perola, M., Kaprio, J., Groop, L., Eriksson, J. G., Ikonen, E., Kallioniemi, O., Pietiainen, V., Palotie, A., Ripatti, S. & ENGAGE Consortium, Jun 2015, In : Nature Genetics. 47, 6, p. 589-597 9 p.

Research output: Contribution to journalArticleScientificpeer-review

The landscape of genomic imprinting across diverse adult human tissues

Baran, Y., Subramaniam, M., Biton, A., Tukiainen, T., Tsang, E. K., Rivas, M. A., Pirinen, M., Gutierrez-Arcelus, M., Smith, K. S., Kukurba, K. R., Zhang, R., Eng, C., Torgerson, D. G., Urbanek, C., Li, J. B., Rodriguez-Santana, J. R., Burchard, E. G., Seibold, M. A., MacArthur, D. G., Montgomery, S. B. & 3 others, Zaitlen, N. A., Lappalainen, T. & GTEx Consortium, Jul 2015, In : Genome Research. 25, 7, p. 927-936 10 p.

Research output: Contribution to journalArticleScientificpeer-review

The transcriptional landscape of age in human peripheral blood

Peters, M. J., Joehanes, R., Pilling, L. C., Schurmann, C., Conneely, K. N., Powell, J., Reinmaa, E., Sutphin, G. L., Zhernakova, A., Schramm, K., Wilson, Y. A., Kobes, S., Tukiainen, T., Ramos, Y. F., Goering, H. H. H., Fornage, M., Liu, Y., Gharib, S. A., Stranger, B. E., De Jager, P. L. & 31 others, Aviv, A., Levy, D., Murabito, J. M., Munson, P. J., Huan, T., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., van Rooij, J., Stolk, L., Broer, L., Verbiest, M. M. P. J., Jhamai, M., Arp, P., Metspalu, A., Tserel, L., Milani, L., Samani, N. J., Peterson, P., Kasela, S., Codd, V., Peters, A., Ward-Caviness, C. K., Herder, C., Waldenberger, M., Roden, M., Hovatta, I., Perola, M., Ripatti, S., Kettunen, J. & NABEC UKBEC Consortium, Oct 2015, In : Nature Communications. 6, 14 p., 8570.

Research output: Contribution to journalArticleScientificpeer-review

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Women's and men's sexual preferences and activities with respect to the partner's age: evidence for female choice

Antfolk, J., Salo, B., Alanko, K., Bergen, E., Corander, J., Sandnabba, N. K. & Santtila, P., Jan 2015, In : Evolution and Human Behavior. 36, 1, p. 73-79 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2016

Analysis of differential splicing suggests different modes of short-term splicing regulation

Topa, H. & Honkela, A., 15 Jun 2016, In : Bioinformatics. 32, 12, p. 147-155 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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An object oriented Python interface for atomistic simulations

Hynninen, T., Himanen, L., Parkkinen, V., Musso, T., Corander, J. & Foster, A. S., Jan 2016, In : Computer Physics Communications. 198, p. 230-237 8 p.

Research output: Contribution to journalArticleScientificpeer-review

A reference panel of 64,976 haplotypes for genotype imputation

McCarthy, S., Das, S., Kretzschmar, W., Delaneau, O., Wood, A. R., Teumer, A., Kang, H. M., Fuchsberger, C., Danecek, P., Sharp, K., Luo, Y., Sidorel, C., Kwong, A., Timpson, N., Koskinen, S., Vrieze, S., Scott, L. J., Zhang, H., Mahajan, A., Veldink, J. & 31 others, Peters, U., Pato, C., van Duijn, C. M., Gillies, C. E., Gandin, I., Mezzavilla, M., Gilly, A., Cocca, M., Traglia, M., Angius, A., Barrett, J. C., Boomsma, D., Branham, K., Breen, G., Brummett, C. M., Busonero, F., Campbell, H., Chan, A., Che, S., Chew, E., Collins, F. S., Corbin, L. J., Smith, G. D., Dedoussis, G., Dorr, M., Farmaki, A-E., Ferrucci, L., Groop, L., Palotie, A., Ripatti, S. & Haplotype Reference Consortium, Oct 2016, In : Nature Genetics. 48, 10, p. 1279-1283 5 p.

Research output: Contribution to journalArticleScientificpeer-review

A tribute to Mats Gyllenberg, on the occasion of his 60th birthday

Corander, J., Diekmann, O. & Koski, T., Mar 2016, In : Journal of mathematical biology. 72, 4, p. 793-795 3 p.

Research output: Contribution to journalArticleScientific

Bayesian identification of bacterial strains from sequencing data

Sankar, A., Malone, B. M., Bayliss, S. C., Pascoe, B., Méric, G., Hitchings, M. D., Sheppard, S. K., Feil, E. J., Corander, J. I. & Honkela, A. J. H., 25 Aug 2016, In : Microbial Genomics. 2, 8, 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Bayesian Optimization for Likelihood-Free Inference of Simulator-Based Statistical Models

Gutmann, M. U. & Corander, J., Aug 2016, In : Journal of Machine Learning Research. 17, 47 p.

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Combined Analysis of Variation in Core, Accessory and Regulatory Genome Regions Provides a Super-Resolution View into the Evolution of Bacterial Populations

McNally, A., Oren, Y., Kelly, D., Pascoe, B., Dunn, S., Sreecharan, T., Vehkala, M., Välimäki, N., Prentice, M. B., Ashour, A., Avram, O., Pupko, T., Dobrindt, U., Literak, I., Guenther, S., Schaufler, K., Wieler, L. H., Zong Zhiyong, Sheppard, S. K., McInerney, J. O. & 1 others, Corander, J., Sep 2016, In : PLoS Genetics. 12, 9, 16 p., 1006280.

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Computing exact clustering posteriors with subset convolution

Kohonen, J. & Corander, J., 2016, In : Communications in Statistics: Theory and Methods. 45, 10, p. 3048-3058 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Context-specific independence in graphical log-linear models

Nyman, H., Pensar, J., Koski, T. & Corander, J., Dec 2016, In : Computational Statistics. 31, 4, p. 1493-1512 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

Sieberts, S. K., Zhu, F., Garcia-Garcia, J., Stahl, E., Pratap, A., Pandey, G., Pappas, D., Aguilar, D., Anton, B., Bonet, J., Eksi, R., Fornes, O., Guney, E., Li, H., Marin, M. A., Panwar, B., Planas-Iglesias, J., Poglayen, D., Cui, J., Falcao, A. O. & 31 others, Suver, C., Hoff, B., Balagurusamy, V. S. K., Dillenberger, D., Neto, E. C., Norman, T., Aittokallio, T., Ammad-ud-din, M., Azencott, C-A., Bellon, V., Boeva, V., Bunte, K., Chheda, H., Cheng, L., Corander, J., Dumontier, M., Goldenberg, A., Gopalacharyulu, P., Hajiloo, M., Hidru, D., Jaiswal, A., Kaski, S., Khalfaoui, B., Khan, S. A., Kramer, E. R., Marttinen, P., Pirinen, M., Saarela, J., Tang, J., Wennerberg, K. & Rheumatoid Arth Challenge, Aug 2016, In : Nature Communications. 7, 9 p., 12460.

Research output: Contribution to journalArticleScientificpeer-review

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Detailed temperature mapping-Warming characterizes archipelago zones

Veneranta, L., Vanhatalo, J. & Urho, L., 5 Dec 2016, In : Estuarine, Coastal and Shelf Science. 182, p. 123-135 13 p.

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Downscaling and extrapolating dynamic seasonal marine forecasts for coastal ocean users

Vanhatalo, J. P., Hobday, A. J., Little, L. R. & Spillman, C. M., Apr 2016, In : Ocean Modelling. 100, p. 20-30 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

Nowak, C., Salihovic, S., Ganna, A., Brandmaier, S., Tukiainen, T., Broeckling, C. D., Magnusson, P. K., Prenni, J. E., Wang-Sattler, R., Peters, A., Strauch, K., Meitinger, T., Giedraitis, V., Arnlov, J., Berne, C., Gieger, C., Ripatti, S., Lind, L., Pedersen, N. L., Sundstrom, J. & 2 others, Ingelsson, E. & Fall, T., Oct 2016, In : PLoS Genetics. 12, 10, 19 p., 1006379.

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Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Hinney, A., Kesselmeier, M., Jall, S., et al., Hebebrand, J., GENETIC CONSORTIUM FOR ANOREXIA NERVOSA (GCAN), WELLCOME TRUST CASE CONTROL CONSORTIUM 3 (WTCCC3), GENETIC INVESTIGATION OF ANTHROPOMETRIC TRAITS CONSORTIUM (GIANT), EARLY GROWTH GENETICS CONSORTIUM (EGG), THE PRICE FOUNDATION COLLABORATIVE GROUP, Raevuori-Helkamaa, A., Palotie, A. & Ripatti, S., 17 May 2016, In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.

Research output: Contribution to journalArticleScientificpeer-review

FINEMAP: efficient variable selection using summary data from genome-wide association studies

Benner, C., Spencer, C. C. A., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., 15 May 2016, In : Bioinformatics. 32, 10, p. 1493-1501 9 p.

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FLOG: Multivariate R Tool for Exploring Biolog Phenotype Microarray Data

Vehkala, M. E., Shubin, M. & Corander, J. I., 16 Aug 2016, (In preparation) In : PLoS One.

Research output: Contribution to journalArticleScientificpeer-review

Genetic Risk Scores Predict Recurrence of Acute Coronary Syndrome

Vaara, S., Tikkanen, E., Parkkonen, O., Lokki, M-L., Ripatti, S., Perola, M., Nieminen, M. S. & Sinisalo, J., Apr 2016, In : Circulation. Cardiovascular genetics. 9, 2, p. 172-178 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic support for the causal role of insulin in coronary heart disease

Tikkanen, E., Pirinen, M., Sarin, A-P., Havulinna, A. S., Mannisto, S., Saltevo, J., Lokki, M-L., Sinisalo, J., Lundqvist, A., Jula, A., Salomaa, V. & Ripatti, S., 2016, In : Diabetologia. 59, 11, p. 2369-2377 9 p.

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Genome-Wide Meta-Analysis of Sciatica in Finnish Population

Lemmelä, S., Solovieva, S., Shiri, R., Benner, C., Heliovaara, M., Kettunen, J., Anttila, V., Ripatti, S., Perola, M., Seppala, I., Juonala, M., Kahonen, M., Salomaa, V., Viikari, J., Raitakari, O. T., Lehtimaki, T., Palotie, A., Viikari-Juntura, E. & Husgafvel-Pursiainen, K., 20 Oct 2016, In : PLoS One. 11, 10, 18 p., 0163877.

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Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

Kettunen, J., Demirkan, A., Wurtz, P., Draisma, H. H. M., Haller, T., Rawal, R., Vaarhorst, A., Kangas, A. J., Lyytikäinen, L-P., Pirinen, M., Pool, R., Sarin, A-P., Soininen, P., Tukiainen, T., Wang, Q., Tiainen, M., Tynkkynen, T., Amin, N., Zeller, T., Beekman, M. & 30 others, Deelen, J., van Dijk, K. W., Esko, T., Hottenga, J-J., van Leeuwen, E. M., Lehtimaki, T., Mihailov, E., Rose, R. J., de Craen, A. J. M., Gieger, C., Kahonen, M., Perola, M., Blankenberg, S., Savolainen, M. J., Verhoeven, A., Viikari, J., Willemsen, G., Boomsma, D. I., van Duijn, C. M., Eriksson, J., Jula, A., Jarvelin, M-R., Kaprio, J., Metspalu, A., Raitakari, O., Salomaa, V., Slagboom, P. E., Waldenberger, M., Ripatti, S. & Ala-Korpela, M., Mar 2016, In : Nature Communications. 7, 9 p., 11122.

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Genome-wide time-to-event analysis on smoking progression stages in a family-based study

He, L., Pitkäniemi, J., Heikkila, K., Chou, Y-L., Madden, P. A. F., Korhonen, T., Sarin, A-P., Ripatti, S., Kaprio, J. & Loukola, A., May 2016, In : Brain and Behavior. 6, 5, 14 p., 00462.

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Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

Spjuth, O., Krestyaninova, M., Hastings, J., Shen, H-Y., Heikkinen, J., Waldenberger, M., Langhammer, A., Ladenvall, C., Esko, T., Persson, M-A., Heggland, J., Dietrich, J., Ose, S., Gieger, C., Ried, J. S., Peters, A., Fortier, I., de Geus, E. J. C., Klovins, J., Zaharenko, L. & 16 others, Willemsen, G., Hottenga, J-J., Litton, J-E., Karvanen, J., Boomsma, D. I., Groop, L., Rung, J., Palmgren, J., Pedersen, N. L., McCarthy, M. I., van Duijn, C. M., Hveem, K., Metspalu, A., Ripatti, S., Prokopenko, I. & Harris, J. R., Apr 2016, In : European Journal of Human Genetics. 24, 4, p. 521-528 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Hydrographic responses to regional covariates across the Kara Sea

Mäkinen, J. A-E. & Vanhatalo, J. P., Dec 2016, In : Journal of Geophysical Research : Oceans. 121, 12, p. 8872-8887 16 p.

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Identifying Multiple Potential Metabolic Cycles in Time-Series from Biolog Experiments

Shubin, M., Schaufler, K., Tedin, K., Vehkala, M. & Corander, J., 27 Sep 2016, In : PLoS One. 11, 9, 14 p., 0162276.

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KardioKompassi yhdistää perimän ja perinteiset riskitekijät sepelvaltimotaudin ehkäisyssä

Ripatti, S. & Widén, E., 2016, In : Duodecim. 132, 10, p. 897-899 3 p.

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Low-Rank Doubly Stochastic Matrix Decomposition for Cluster Analysis

Yang, Z., Corander, J. & Oja, E., 2016, In : Journal of Machine Learning Research. 17, 187, p. 1-25 25 p., 1.

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Marginal and simultaneous predictive classification using stratified graphical models

Nyman, H., Xiong, J., Pensar, J. & Corander, J., Sep 2016, In : Advances in Data Analysis and Classification. 10, 3, p. 305-326 22 p.

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Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

Jarvis, D., Mitchell, J. S., Law, P. J., Palin, K., Tuupanen, S., Gylfe, A., Hanninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Kaprio, J., Eriksson, J. G., Rissanen, H., Knekt, P., Pukkala, E., Jousilahti, P., Salomaa, V., Ripatti, S. & 37 others, Palotie, A., Järvinen, H., Renkonen-Sinisalo, L., Lepistö, A., Bohm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Buchanan, D. D., Win, A. K., Hopper, J. L., Jenkins, M. A., Lindor, N. M., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F., Casey, G., Taipale, J., Aaltonen, L. A., Cheadle, J. P., Dunlop, M. G., Tomlinson, I. P. & Houlston, R. S., 12 Jul 2016, In : British Journal of Cancer. 115, 2, p. 266-272 7 p.

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Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems

Shu, L., Zhao, Y., Kurt, Z., Byars, S. G., Tukiainen, T., Kettunen, J., Orozco, L. D., Pellegrini, M., Lusis, A. J., Ripatti, S., Zhang, B., Inouye, M., Makinen, V-P. & Yang, X., 4 Nov 2016, In : BMC Genomics. 17, 16 p., 874.

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Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

van Leeuwen, E. M., Sabo, A., Bis, J. C., Huffman, J. E., Manichaikul, A., Smith, A. V., Feitosa, M. F., Demissie, S., Joshi, P. K., Duan, Q., Marten, J., van Klinken, J. B., Surakka, I., Nolte, I. M., Zhang, W., Mbarek, H., Li-Gao, R., Trompet, S., Verweij, N., Evangelou, E. & 31 others, Lyytikainen, L-P., Tayo, B. O., Deelen, J., van der Most, P. J., van der Laan, S. W., Arking, D. E., Morrison, A., Dehghan, A., Franco, O. H., Hofman, A., Rivadeneira, F., Sijbrands, E. J., Uitterlinden, A. G., Mychaleckyj, J. C., Campbell, A., Hocking, L. J., Padmanabhan, S., Brody, J. A., Rice, K. M., White, C. C., Harris, T., Isaacs, A., Campbell, H., Lange, L. A., Rudan, I., Kolcic, I., Navarro, P., Zemunik, T., Salomaa, V., Ripatti, S. & CHARGE Lipids Working Grp, Jul 2016, In : Journal of Medical Genetics. 53, 7, p. 441-449 9 p.

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metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

Cichonska, A., Rousu, J., Marttinen, P., Kangas, A. J., Soininen, P., Lehtimaki, T., Raitakari, O. T., Jarvelin, M-R., Salomaa, V., Ala-Korpela, M., Ripatti, S. & Pirinen, M., 1 Jul 2016, In : Bioinformatics. 32, 13, p. 1981-1989 9 p.

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Monomorphic genotypes within a generalist lineage of Campylobacter jejuni show signs of global dispersion

Llarena, A-K., Zhang, J., Vehkala, M., Välimäki, N., Hakkinen, M., Hänninen, M-L., Roasto, M., Mäesaar, M., Taboada, E., Barker, D., Garofolo, G., Cammà, C., Di Giannatale, E., Corander, J. & Rossi, M., 1 Oct 2016, In : Microbial Genomics. 2, 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Multiple Output Regression with Latent Noise

Gillberg, J., Marttinen, P., Pirinen, M., Kangas, A. J., Soininen, P., Ali, M., Havulinna, A. S., Järvelin, M-R., Ala-Korpela, M. & Kaski, S., 1 Jan 2016, In : Journal of Machine Learning Research. 17, 1, p. 4170-4204 35 p.

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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, A. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S. & 239 others, Lagou, V., Li, R., Li, X., Locke, A., Lu, C., Magi, R., Perry, J. R. B., Pers, T. H., Qi, Q., Sanna, M., Schmidt, E. M., Scott, W. R., Shungin, D., Teumer, A., Vinkhuyzen, A. A. E., Walker, R. W., Westra, H-J., Zhang, M., Zhang, W., Zhao, J. H., Zhu, Z., Afzal, U., Ahluwalia, T. S., Bakker, S. J. L., Bellis, C., Bonnefond, A., Borodulin, K., Buchman, A. S., Cederholm, T., Choh, A. C., Choi, H. J., Curran, J. E., de Groot, L. C. P. G. M., De Jager, P. L., Dhonukshe-Rutten, R. A. M., Enneman, A. W., Eury, E., Evans, D. S., Forsen, T., Friedrich, N., Fumeron, F., Garcia, M. E., Gartner, S., Han, B-G., Havulinna, A. S., Hayward, C., Hernandez, D., Hillege, H., Ittermann, T., Kent, J. W., Kolcic, I., Laatikainen, T., Lahti, J., Leach, I. M., Lee, C. G., Lee, J-Y., Liu, T., Liu, Y., Lobbens, S., Loh, M., Lyytikainen, L-P., Medina-Gomez, C., Michaelsson, K., Nalls, M. A., Nielson, C. M., Oozageer, L., Pascoe, L., Paternoster, L., Polasek, O., Ripatti, S., Sarzynski, M. A., Shin, C. S., Narancic, N. S., Spira, D., Srikanth, P., Steinhagen-Thiessen, E., Sung, Y. J., Swart, K. M. A., Taittonen, L., Tanaka, T., Tikkanen, E., van der Velde, N., van Schoor, N. M., Verweij, N., Wright, A. F., Yu, L., Zmuda, J. M., Pellikka, N., Forrester, T., Grarup, N., Jackson, A. U., Kristiansson, K., Kuulasmaa, T., Kuusisto, J., Lichtner, P., Luan, J., Mahajan, A., Mannisto, S., Palmer, C. D., Ried, J. S., Scott, R. A., Stancakova, A., Wagner, P. J., Demirkan, A., Doring, A., Gudnason, V., Kiel, D. P., Kuhnel, B., Mangino, M., Mcknight, B., Menni, C., O'Connell, J. R., Oostra, B. A., Shuldiner, A. R., Song, K., Vandenput, L., van Duijn, C. M., Vollenweider, P., White, C. C., Boehnke, M., Boettcher, Y., Cooper, R. S., Forouhi, N. G., Gieger, C., Grallert, H., Hingorani, A., Jorgensen, T., Jousilahti, P., Kivimaki, M., Kumari, M., Laakso, M., Langenberg, C., Linneberg, A., Luke, A., Mckenzie, C. A., Palotie, A., Pedersen, O., Peters, A., Strauch, K., Tayo, B. O., Wareham, N. J., Bennett, D. A., Bertram, L., Blangero, J., Bluher, M., Bouchard, C., Campbell, H., Cho, N. H., Cummings, S. R., Czerwinski, S. A., Demuth, I., Eckardt, R., Eriksson, J. G., Ferrucci, L., Franco, O. H., Froguel, P., Gansevoort, R. T., Hansen, T., Harris, T. B., Hastie, N., Heliovaara, M., Hofman, A., Jordan, J. M., Jula, A., Kahonen, M., Kajantie, E., Knekt, P. B., Koskinen, S., Kovacs, P., Lehtimaki, T., Lind, L., Liu, Y., Orwoll, E. S., Osmond, C., Perola, M., Perusse, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Rivadeneira, F., Rudan, I., Salomaa, V., Sorensen, T. I. A., Stumvoll, M., Tonjes, A., Towne, B., Tranah, G. J., Tremblay, A., Uitterlinden, A. G., van der Harst, P., Vartiainen, E., Viikari, J. S., Vitart, V., Vohl, M-C., Volzke, H., Walker, M., Wallaschofski, H., Wild, S., Wilson, J. F., Yengo, L., Bishop, D. T., Borecki, I. B., Chambers, J. C., Cupples, L. A., Dehghan, A., Deloukas, P., Fatemifar, G., Fox, C., Furey, T. S., Franke, L., Han, J., Hunter, D. J., Karjalainen, J., Karpe, F., Kaplan, R. C., Kooner, J. S., McCarthy, M. I., Murabito, J. M., Morris, A. P., Bishop, J. A. N., North, K. E., Ohlsson, C., Ong, K. K., Prokopenko, I., Richards, J. B., Schadt, E. E., Spector, T. D., Widen, E., Willer, C. J., Yang, J., Ingelsson, E., Mohlke, K. L., Hirschhorn, J. N., Pospisilik, J. A., Zillikens, M. C., Lindgren, C., Kilpelainen, T. O. & Loos, R. J. F., Feb 2016, In : Nature Communications. 7, 15 p., 10495.

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No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

Loley, C., Alver, M., Assimes, T. L., Bjonnes, A., Goel, A., Gustafsson, S., Hernesniemi, J., Hopewell, J. C., Kanoni, S., Kleber, M. E., Lau, K. W., Lu, Y., Lyytikainen, L-P., Nelson, C. P., Nikpay, M., Qu, L., Salfati, E., Scholz, M., Tukiainen, T., Willenborg, C. & 58 others, Won, H-H., Zeng, L., Zhang, W., Anand, S. S., Beutner, F., Bottinger, E. P., Clarke, R., Dedoussis, G., Do, R., Esko, T., Eskola, M., Farrall, M., Gauguier, D., Giedraitis, V., Granger, C. B., Hall, A. S., Hamsten, A., Hazen, S. L., Huang, J., Kahonen, M., Kyriakou, T., Laaksonen, R., Lind, L., Lindgren, C., Magnusson, P. K. E., Marouli, E., Mihailov, E., Morris, A. P., Nikus, K., Pedersen, N., Rallidis, L., Salomaa, V., Shah, S. H., Stewart, A. F. R., Thompson, J. R., Zalloua, P. A., Chambers, J. C., Collins, R., Ingelsson, E., Iribarren, C., Karhunen, P. J., Kooner, J. S., Lehtimaki, T., Loos, R. J. F., Maerz, W., McPherson, R., Metspalu, A., Reilly, M. P., Ripatti, S., Sanghera, D. K., Thiery, J., Watkins, H., Deloukas, P., Kathiresan, S., Samani, N. J., Schunkert, H., Erdmann, J. & Koenig, I. R., 12 Oct 2016, In : Scientific Reports. 6, 9 p., 35278.

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Open Access
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On the Identifiability of Transmission Dynamic Models for Infectious Diseases

Lintusaari, J., Gutmann, M. U., Kaski, S. & Corander, J., Mar 2016, In : Genetics. 202, 3, p. 911-918 8 p.

Research output: Contribution to journalArticleScientificpeer-review