CAN-PRO - Translational Cancer Medicine Program

Mari-Mia Ainola
- mari.ainolahelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - University Researcher
Person: U3 Research and teaching staff
19982024
Kari Alitalo
- kari.alitalohelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - Research Director
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Biomedicine - Supervisor for doctoral programme
- HUSLAB
Person: U4 Research and teaching staff
19772025
Andrey Anisimov
- andrey.anisimovhelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - Specialist
Person: M5 Teaching and research support staff
20072024
Johanna Anttila
- johanna.m.anttilahelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - Postdoctoral Researcher
Person: U2 Teaching and research staff
20172024
Gauri Anil Arolkar
- gauri.arolkarhelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - Doctoral Researcher
- Doctoral Programme in Biomedicine
Person: U1 Research and teaching staff, Doctoral Researcher

Cell Communication
CAN-PRO - Translational Cancer Medicine Program
Organisational unit: Research group

96-well PCR-machine
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › PCR equipment
Benchtop centrifuge
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › Centrifuges
Brightfield microscope
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › Microscopes and related accessories
HTP Bright Field & Fluorescence Scanner
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › Scanners
Laminar air flow cabinet (BVC users)
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › Safety equipment and cabinets

13 Finished
28 Active

EU HE/MSC/Vanharanta/Adaptmet/101169223
Vanharanta, S. (Project manager)
European Commission
01/03/2025 → 28/02/2029
Project: EU Horizon Europe: MSCA Doctoral Networks (HORIZON-TMA-MSCA-DN)
Syöpäsäätiö 2025 Saharinen Pipsa
Saharinen, P. (Project manager)
Syöpäsäätiö sr Cancerstiftelsen sr
01/01/2025 → 31/12/2025
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
Syöpäsäätiö2025
Ojala, P. M. (Project manager)
Syöpäsäätiö sr Cancerstiftelsen sr
01/01/2025 → 31/12/2025
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
Imusuonten rooli keuhkosyövässä ja etäpe
Mäkinen, T. (Project manager) & Faragó, T. (Participant)
Syöpäsäätiö sr Cancerstiftelsen sr
01/01/2025 → 31/12/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
Syöpäsäätiö 2025/Alitalo
Alitalo, K. (Project manager), Bessone, C. (Participant), Kallio, P. (Participant) & Lassila, M. J. J. (Participant)
Syöpäsäätiö sr Cancerstiftelsen sr
01/01/2025 → 31/12/2025
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)

Cancer cells impair monocyte-mediated T cell stimulation to evade immunity
Elewaut, A., Estivill, G., Bayerl, F., Castillon, L., Novatchkova, M., Pottendorfer, E., Hoffmann-Haas, L., Schönlein, M., Nguyen, T. V., Lauss, M., Andreatta, F., Vulin, M., Krecioch, I., Bayerl, J., Pedde, A. M., Fabre, N., Holstein, F., Cronin, S. M., Rieser, S. & Laniti, D. D. & 11 others, Barras, D., Coukos, G., Quek, C., Bai, X., Muñoz i Ordoño, M., Wiesner, T., Zuber, J., Jönsson, G., Böttcher, J. P., Vanharanta, S. & Obenauf, A. C., 2025, In: Nature. 637, p. 716-725 40 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Direct specification of lymphatic endothelium from mesenchymal progenitors
Lupu, I.-E., Grainger, D. E., Kirschnick, N., Weischer, S., Zhao, E., Martinez-Corral, I., Schoofs, H., Vanhollebeke, M., Jones, G., Godwin, J., Forrow, A., Lahmann, I., Riley, P. R., Zobel, T., Alitalo, K., Mäkinen, T., Kiefer, F. & Stone, O. A., 2 Jan 2025, In: Nature Cardiovascular Research. 4, 1, p. 45–63 39 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Disitamab vedotin in preclinical models of HER2-positive breast and gastric cancers resistant to trastuzumab emtansine and trastuzumab deruxtecan
Pourjamal, N., Le Joncour, V., Vereb, G., Honkamäki, C., Isola, J., Leyton, J. V., Laakkonen, P., Joensuu, H. & Barok, M., Mar 2025, In: Translational oncology. 53, 9 p., 102284.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium
Schoofs, H., Daubel, N., Schnabellehner, S., Grönloh, M. L. B., Martinez, S. P., Halme, A., Marks, A. M., Jeansson, M., Barcos, S., Brakebusch, C., Benedito, R., Engelhardt, B., Vestweber, D., Gaengel, K., Linsenmeier, F., Schurmann, S., Saharinen, P., van Buul, J. D., Friedrich, O. & Smith, R. S. & 2 others, Majda, M. & Mäkinen, T., 2025, In: Nature. 39 p., 2869.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
Establishing a GMP-compliant manufacturing process and phase-appropriate analytics for early development of a FiCAR T-cell product with a novel CAR spacer
Luostarinen, A., Vuorela, A., Kerkelä, E., Patrikoski, M., Kotovuori, A., Koski, J., Ahoniemi, J., Lähteenmäki, K., Lehtisalo, J., Oja, T., Paavilainen, H., Autio, A., Nyman, M., Nikoskelainen, V., Kergourlay, V., Elbasani, E., van Veen, B., Thotakura, A., Monzo, H. & Ojala, P. M. & 3 others, Korhonen, M., Hongisto, H. & Laitinen, A., 8 Mar 2025, In: Scientific Reports. 15, 1, 17 p., 8093.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File

Translational Cancer Medicine Research Program kick-off event
Vaahtomeri, K. (Attendee)
31 Aug 2027
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
SDF-1alpha, SCF, and eotaxin are prognostic serum biomarkers in gastric cancer
Brodkin, J. H. (Speaker)
24 May 2024
Activity: Talk or presentation types › Oral presentation
Cell-type specific apoptotic patterns in pancreatis cancer stromal–tumor co-culture organoids
Brodkin, J. H. (Speaker)
3 Oct 2024
Activity: Talk or presentation types › Oral presentation
iCAN retreat 2024
Kremneva, E. (Chair of organizing committee), Kolikova, Y. (Member of organizing committee), Laakkonen, P. (Member of organizing committee), Vanharanta, S. (Member of organizing committee), Varjosalo, M. (Member of organizing committee), Wahl, H. (Member of organizing committee), Sankkila-Forsström, S. S. (Member of organizing committee), Duàn, H. (Speaker: Presenter), Karhemo, P.-R. (Speaker: Presenter), Miihkinen, M. S. (Speaker: Presenter), Liljeström, M. (Member of organizing committee), Pietiäinen, V. (Speaker: Presenter), Ganesan, A. (Poster Presentation), Saad, J. (Poster Presentation), Holmström, S. (Poster Presentation), Brodkin, J. H. (Poster Presentation), Mendoza Ortiz, E. D. (Poster Presentation), Sundaresan, S. (Poster Presentation), Chiaro, J. (Poster Presentation), Giannoula, Y. (Poster Presentation), Portaankorva, A. M. (Speaker: Presenter), Mustjoki, S. (Speaker: Presenter), Mäkelä, T. (Speaker: Presenter), Atarsaikhan, G. (Poster Presentation), Filppu, P. (Poster Presentation), Russo, S. (Poster Presentation), Pikkusaari, S. K. (Poster Presentation), Ryzhenkov, A. (Poster Presentation), Newman, R. G. D. (Speaker: Presenter), Arffman, M. E. (Speaker: Presenter), Kumari, R. (Poster Presentation), Leppiniemi, S. A. (Poster Presentation), Sanjaya, P. (Poster Presentation), Feodoroff, M. J. (Poster Presentation), Karabayev, D. (Poster Presentation), Jäntti, J. M. (Poster Presentation), Wong Ramirez, J. R. C. (Poster Presentation), Kalander, K. O. (Poster Presentation), Bouhlal, J. O. V. (Speaker: Presenter), Kuusela, S. (Speaker: Presenter), Fey, E. (Speaker: Presenter), Krami Senhaji, O. (Poster Presentation), Moradi, N. (Poster Presentation), Polso, M. M. M. (Poster Presentation), Antignani, G. (Poster Presentation), Maljanen, K. J. (Poster Presentation), Langohr, L. (Poster Presentation), Anil, A. (Poster Presentation), Smolander, P. J. (Poster Presentation), Feodoroff, M. J. (Poster Presentation), Alsaed, B. (Poster Presentation), Mogollon Figueroa, I. (Poster Presentation), Ryzhenkov, A. (Poster Presentation) & Henriksson, M. E. J. (Poster Presentation)
3 Oct 2024
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Co-supervision of PhD docpilot student
Tuohinto, K. (Supervisor)
2024 → …
Activity: Examination types › Supervisor or co-supervisor of doctoral thesis

A.I. Virtanen Prize
Alitalo, K. (Recipient), 2013
Prize: Prizes and awards
Academy Research Fellow
Karaman, S. (Recipient), Sept 2020
Prize: Prizes and awards
Academy Research Fellow: Research costs
Karaman, S. (Recipient), Sept 2020
Prize: Prizes and awards
Best presentation and poster award: Discovery of Novel Biomarkers and Target Molecules
Laakkonen, P. (Recipient), 12 May 2009
Prize: Prizes and awards
Biomedicum Helsinki Foundation Young Scientist Award 2010
Bry, M. (Recipient), 2010
Prize: Prizes and awards

Patenttihakemus
Alitalo, K. K. (Creator), Lemström, K. (Creator) & Nykänen, A. (Creator), Licentia and Ludwig Institute for Cancer Research, 2007
Dataset
Patenttihakemus
Alitalo, K. K. (Creator), Syrjälä, S. O. (Creator) & Lemström, K. (Creator), University of Helsinki, 2013
Dataset

Tutkimuksen maailma tutummaksi myös potilaille
Lahti, T. & Tran Minh, A. M.
10/05/2021
1 Media contribution
Press/Media: Press / Media
Tutkimus ei yksin riitä
Tran Minh, A. M.
18/02/2021
1 Media contribution
Press/Media: Press / Media
Short review: Kaposin Sarkoma – Enigmaattinen virusperäinen syöpä.
Tuohinto, K.
01/05/2020
1 Media contribution
Press/Media: Press / Media
“Achilles Heel” of Glioblastoma Found?
Laakkonen, P.
21/10/2019
1 item of Media coverage
Press/Media: Press / Media
Scientific editorial: Virukset ja syöpä – mitä uutta?
Tuohinto, K.
01/09/2019
1 Media contribution
Press/Media: Press / Media

CAN-PRO - Translational Cancer Medicine Program

International and National Collaboration

Profiles

Research units

Equipment

Projects

Publications

Activities

Prizes

Datasets

Press/Media