CAN-PRO - Translational Cancer Medicine Program

Mari-Mia Ainola
- mari.ainolahelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - University Researcher
- HUS Heart and Lung Center
- HUS Internal Medicine and Rehabilitation
Person: U3 Research and teaching staff
19982025
Kari Alitalo
- kari.alitalohelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - Research Director
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Biomedicine - Supervisor for doctoral programme
- HUS Radiology and Pathology
Person: U4 Research and teaching staff
19772026
Andrey Anisimov
- andrey.anisimovhelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - Specialist
Person: M5 Teaching and research support staff
20072024
Gauri Anil Arolkar
- gauri.arolkarhelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - Doctoral Researcher
- Doctoral Programme in Biomedicine
Person: U1 Research and teaching staff, Doctoral Researcher
July Aung
- july.aunghelsinkifi
- CAN-PRO - Translational Cancer Medicine Program - Doctoral Researcher
- Doctoral Programme in Biomedicine
Person: U1 Research and teaching staff, Doctoral Researcher
20242025

Cell Communication
CAN-PRO - Translational Cancer Medicine Program
Organisational unit: Research group

96-well PCR-machine
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › PCR equipment
Benchtop centrifuge
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › Centrifuges
Brightfield microscope
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › Microscopes and related accessories
HTP Bright Field & Fluorescence Scanner
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › Scanners
Laminar air flow cabinet (BVC users)
CAN-PRO - Translational Cancer Medicine Program
Facility/equipment: Registry of appliances: Laboratory equipment › Safety equipment and cabinets

3 Not started
15 Finished
30 Active

Paracrine and tissue-specific mechanisms of lymphatic vessel growth and regeneration
Mäkinen, T. (Project manager) & Varaliová, Z. (Participant)
Academy of Finland
01/09/2025 → 31/08/2029
Project: Research Council of Finland: Academy Project
Viral Hijacking of Pioneer Activity: Unveiling a Developmental Transcription Factor's Novel Role in Oncogenic Viral Infection and Host 3D Genome Remodeling
Ojala, P. M. (Project manager)
Academy of Finland
01/09/2025 → 31/08/2029
Project: Research Council of Finland: Academy Project
EMBO Vishal
Mäkinen, T. (Project manager) & Mohanakrishnan, V. (Participant)
EMBO Solutions GmbH
01/09/2025 → 31/08/2027
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
Saharinen Juselius 2025-2028
Saharinen, P. (Project manager)
Sigrid Juséliuksen Säätiö @003701165704@
01/05/2025 → 30/04/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
"Lymphatic endothelium in control of ant
Vaahtomeri, K. (Project manager)
Sigrid Juséliuksen Säätiö @003701165704@
01/05/2025 → 30/04/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)

A Multipotent PROX1+ Tumor Stem/Progenitor Cell Population Emerges During Intestinal Tumorigenesis and Mediates Radioresistance in Colorectal Cancer
Kallio-Koistinen, P., Bessone, C., Seyednasrollah, F., Brodkin, J., Lassila, M., Högström, J., González‐Loyola, A., Petrova, T. V., Haglund, C. & Alitalo, K., 1 Dec 2025, In: Cancer Research. 85, 23, p. 4616-4631 16 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Angiopoietin-TIE2 feedforward circuit promotes PIK3CA-driven venous malformations
Kraft, M., Schoofs, H., Petkova, M., Andrade, J., Grosso, A. R., Benedito, R., De Roo, A.-K., Boon, L. M., Vikkula, M., Kapp, F. G., Hagerling, R., Potente, M. & Mäkinen, T., Jul 2025, In: Nature Cardiovascular Research. 4, 7, 40 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Angiotensin receptor blocker and angiotensinconverting enzyme inhibitor use and survival in gastric cancer patients: a Finnish nationwide cohort study
Auvinen, A., Aaltonen, P., Mustonen, H., Haglund, C., Puolakkainen, P. & Seppänen, H., Nov 2025, In: Gastric Cancer. 28, 6, p. 1058-1066 9 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
An immunohistochemistry-based classification of colorectal cancer resembling the consensus molecular subtypes using convolutional neural networks
Kaprio, T., Hagström, J., Kasurinen, J., Gkekas, I., Edin, S., Beilmann-Lehtonen, I., Strigard, K., Palmqvist, R., Gunnarson, U., Böckelman, C. & Haglund, C., 31 May 2025, In: Scientific Reports. 15, 1, 10 p., 19105.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
A TOM1 variant impairs interaction with TOLLIP, autophagosome-lysosome fusion and regulation of innate immunity
Lång, H. K. M., Roach, T. G., Hölttä, M., Keskitalo, S., Varjosalo, M., Collins, M. V., Seppänen, M. R. J., Capelluto, D. G. S., Ikonen, E. & Ryhänen, S. J., 30 Sept 2025, In: Disease Models & Mechanisms. 18, 9, 11 p., dmm052140.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File

Translational Cancer Medicine Research Program kick-off event
Vaahtomeri, K. (Attendee)
31 Aug 2027
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Cell-type specific apoptotic patterns in pancreatis cancer stromal–tumor co-culture organoids
Brodkin, J. H. (Speaker)
3 Oct 2024
Activity: Talk or presentation types › Oral presentation
SDF-1alpha, SCF, and eotaxin are prognostic serum biomarkers in gastric cancer
Brodkin, J. H. (Speaker)
24 May 2024
Activity: Talk or presentation types › Oral presentation
Co-supervision of PhD docpilot student
Tuohinto, K. (Supervisor)
2024 → …
Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
iCAN retreat 2024
Kremneva, E. (Chair of organizing committee), Kolikova, Y. (Member of organizing committee), Laakkonen, P. (Member of organizing committee), Vanharanta, S. (Member of organizing committee), Varjosalo, M. (Member of organizing committee), Wahl, H. (Member of organizing committee), Sankkila-Forsström, S. S. (Member of organizing committee), Duàn, H. (Speaker: Presenter), Karhemo, P.-R. (Speaker: Presenter), Miihkinen, M. S. (Speaker: Presenter), Liljeström, M. (Member of organizing committee), Pietiäinen, V. (Speaker: Presenter), Ganesan, A. (Poster Presentation), Saad, J. (Poster Presentation), Holmström, S. (Poster Presentation), Brodkin, J. H. (Poster Presentation), Mendoza Ortiz, E. D. (Poster Presentation), Sundaresan, S. (Poster Presentation), Chiaro, J. (Poster Presentation), Giannoula, Y. (Poster Presentation), Portaankorva, A. M. (Speaker: Presenter), Mustjoki, S. (Speaker: Presenter), Mäkelä, T. (Speaker: Presenter), Atarsaikhan, G. (Poster Presentation), Filppu, P. (Poster Presentation), Russo, S. (Poster Presentation), Pikkusaari, S. K. (Poster Presentation), Ryzhenkov, A. (Poster Presentation), Newman, R. G. D. (Speaker: Presenter), Arffman, M. E. (Speaker: Presenter), Kumari, R. (Poster Presentation), Leppiniemi, S. A. (Poster Presentation), Sanjaya, P. (Poster Presentation), Feodoroff, M. J. (Poster Presentation), Karabayev, D. (Poster Presentation), Jäntti, J. M. (Poster Presentation), Wong Ramirez, J. R. C. (Poster Presentation), Kalander, K. O. (Poster Presentation), Bouhlal, J. O. V. (Speaker: Presenter), Kuusela, S. (Speaker: Presenter), Fey, E. (Speaker: Presenter), Krami Senhaji, O. (Poster Presentation), Moradi, N. (Poster Presentation), Polso, M. M. M. (Poster Presentation), Antignani, G. (Poster Presentation), Maljanen, K. J. (Poster Presentation), Langohr, L. (Poster Presentation), Anil, A. (Poster Presentation), Smolander, P. J. (Poster Presentation), Feodoroff, M. J. (Poster Presentation), Alsaed, B. (Poster Presentation), Mogollon Figueroa, I. (Poster Presentation), Ryzhenkov, A. (Poster Presentation) & Henriksson, M. E. J. (Poster Presentation)
3 Oct 2024
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars

A.I. Virtanen Prize
Alitalo, K. (Recipient), 2013
Prize: Prizes and awards
Academy Research Fellow
Karaman, S. (Recipient), Sept 2020
Prize: Prizes and awards
Academy Research Fellow: Research costs
Karaman, S. (Recipient), Sept 2020
Prize: Prizes and awards
Best presentation and poster award: Discovery of Novel Biomarkers and Target Molecules
Laakkonen, P. (Recipient), 12 May 2009
Prize: Prizes and awards
Biomedicum Helsinki Foundation Young Scientist Award 2010
Bry, M. (Recipient), 2010
Prize: Prizes and awards

Patenttihakemus
Alitalo, K. K. (Creator), Syrjälä, S. O. (Creator) & Lemström, K. (Creator), University of Helsinki, 2013
Dataset
Patenttihakemus
Alitalo, K. K. (Creator), Lemström, K. (Creator) & Nykänen, A. (Creator), Licentia and Ludwig Institute for Cancer Research, 2007
Dataset

Tutkimuksen maailma tutummaksi myös potilaille
Lahti, T. & Tran Minh, A. M.
10/05/2021
1 Media contribution
Press/Media: Press / Media
Tutkimus ei yksin riitä
Tran Minh, A. M.
18/02/2021
1 Media contribution
Press/Media: Press / Media
Short review: Kaposin Sarkoma – Enigmaattinen virusperäinen syöpä.
Tuohinto, K.
01/05/2020
1 Media contribution
Press/Media: Press / Media
“Achilles Heel” of Glioblastoma Found?
Laakkonen, P.
21/10/2019
1 item of Media coverage
Press/Media: Press / Media
Scientific editorial: Virukset ja syöpä – mitä uutta?
Tuohinto, K.
01/09/2019
1 Media contribution
Press/Media: Press / Media

CAN-PRO - Translational Cancer Medicine Program

Collaborations and top research areas from the last five years

Profiles

Research units

Equipment

Projects

Research output

Activities

Prizes

Datasets

Press/Media