Publications 1997 2019

2019

Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in beta Cells

Zhang, E., Al-Amily, I. M., Mohammed, S., Luan, C., Asplund, O., Ahmed, M., Ye, Y., Ben-Hail, D., Soni, A., Vishnu, N., Bompada, P., De Marinis, Y., Groop, L., Shoshan-Barmatz, V., Renstrom, E., Wollheim, C. B. & Salehi, A., 8 Jan 2019, In : Cell Metabolism. 29, 1, p. 64-+ 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Prognostic value of blood and lymphatic vessel markers in tongue cancer: A Systematic Review

Almahmoudi, R., Kasanen, M., Sieviläinen, M., Salem, A., Pirinen, M., Salo, T. & Al-Samadi, A., 30 Sep 2019, In : Cancer Science. 10 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File

Roadmap for a precision-medicine initiative in the Nordic region

Njolstad, P. R., Andreassen, O. A., Brunak, S., Borglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, M., Metspalu, A., Mortensen, P. B., Palmgren, J. & 11 othersPalotie, A., Reed, W., Stefansson, H., Stitziel, N. O., Sullivan, P. F., Thorsteinsdottir, U., Vaudel, M., Vuorio, E., Werge, T., Stoltenberg, C. & Stefansson, K., Jun 2019, In : Nature Genetics. 51, 6, p. 924-930 7 p.

Research output: Contribution to journalEditorialScientificpeer-review

Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis

UK10K Consortium, Yang, Y., van der Klaauw, A. A., Lonnqvist, J., Palotie, A., Paunio, T., Pietilainen, O. & Suvisaari, J., 12 Apr 2019, In : Nature Communications. 10, 14 p., 1718.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

The associations of daylight and melatonin receptor 1B gene rs10830963 variant with glycemic traits: the prospective PPP-Botnia study

Haljas, K., Hakaste, L., Lahti, J., Isomaa, B., Groop, L., Tuomi, T. & Räikkönen, K., 2 Jan 2019, In : Annals of Medicine. 51, 1, p. 58-67 10 p.

Research output: Contribution to journalArticleScientificpeer-review

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

Early Genetics Lifecourse, EGG Consortium, EGG Membership, EAGLE Membership, Middeldorp, C. M., Mahajan, A., Auvinen, J., Eriksson, J. G., Groop, L., Kaprio, J., Lahti, J., Palviainen, T., Strandberg, T., Vuoksimaa, E. & Widen, E. E., Mar 2019, In : European Journal of Epidemiology. 34, 3, p. 279-300 22 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Transient modification of lin28b expression - Permanent effects on zebrafish growth

Leinonen, J. T., Chen, Y-C., Tukiainen, T., Panula, P. & Widen, E., 5 Jan 2019, In : Molecular and Cellular Endocrinology. 479, p. 61-70 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study

van Essen, T. A., den Boogert, H. F., Cnossen, M. C., CENTER-TBI Investigators Partici, Kaukonen, M., Kivisaari, R., Piippo-Karjalainen, A., Raj, R., Tanskanen, P., Palotie, A., Pirinen, M. & Ripatti, S., Mar 2019, In : Acta Neurochirurgica. 161, 3, p. 435-449 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
2018

2017 William Allan Award Introduction: Kari Stefansson

Daly, M. J., 1 Mar 2018, In : American Journal of Human Genetics. 102, 3, p. 350-350 1 p.

Research output: Contribution to journalEditorialScientificpeer-review

Open Access
File

Age at first birth in women is genetically associated with increased risk of schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Eriksson, J. G., Paunio, T. M., Pietiläinen, O. K. & Palotie, A. V., 5 Jul 2018, In : Scientific Reports. 8, 14 p., 10168.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Akuutti ripuli

Färkkilä, M., 2018, Akuuttihoito-opas . Mäkijärvi, M., Harjola, V-P., Päivä, H., Valli, J. & Vaula, E. (eds.). 20. uud. p. ed. Helsinki: Kustannus Oy Duodecim, p. 212-214 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Analysis of shared heritability in common disorders of the brain

Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y. & 33 othersBerr, C., Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J-F., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Palta, P., Wedenoja, J., Artto, V., Kaunisto, M., Vepsäläinen, S., Kurki, M. I., Hämäläinen, E., Kaprio, J., Metspalu, A., Keski-Rahkonen, A., Raevuori, A., Ripatti, S., Lönnqvist, J., Daly, M., Palotie, A. & Neale, B. M., 22 Jun 2018, In : Science. 360, 6395, p. 1313-+ 13 p., 8757.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Association between genetic risk variants and glucose intolerance during pregnancy in north Indian women

Arora, G. P., Almgren, P., Brons, C., Thaman, R. G., Vaag, A. A., Groop, L. & Prasad, R. B., 8 Aug 2018, In : BMC Medical Genomics. 11, 10 p., 64.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes

SUMMIT Consortium, 19 Dec 2018, In : PLoS One. 13, 12, 13 p., 0208654.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Base-specific mutational intolerance near splice sites clarifies the role of nonessential splice nucleotides

Zhang, S., Samocha, K. E., Rivas, M. A., Karczewski, K. J., Daly, E., Schmandt, B., Neale, B. M., MacArthur, D. G. & Daly, M. J., Jul 2018, In : Genome Research. 28, 7, p. 968-974 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits

Haljas, K., Amare, A. T., Alizadeh, B. Z., Hsu, Y-H., Mosley, T., Newman, A., Murabito, J., Tiemeier, H., Tanaka, T., van Duijn, C., Ding, J., Llewellyn, D. J., Bennett, D. A., Terracciano, A., Launer, L., Ladwig, K-H., Cornelis, M. C., Teumer, A., Grabe, H., Kardia, S. L. R. & 7 othersWare, E. B., Smith, J. A., Snieder, H., Eriksson, J. G., Groop, L., Räikkönen, K. & Lahti, J., Apr 2018, In : Psychosomatic Medicine. 80, 3, p. 242-251 10 p.

Research output: Contribution to journalArticleScientificpeer-review

C-hepatiitti - maksasairauden hoidosta infektion eliminaatioon: Hoitopolku erikoissairaanhoidosta perusterveydenhuoltoon

Färkkilä, M., 2018, In : Duodecim. 134, 17, p. 1655-1657 3 p.

Research output: Contribution to journalEditorialProfessional

Open Access
File
Open Access
File

Coffee consumption, genetic susceptibility and risk of latent autoimmune diabetes in adults: A population-based case-control study

Rasouli, B., Ahlqvist, E., Alfredsson, L., Andersson, T., Carlsson, P-O., Groop, L., Löfvenborg, J. E., Martinell, M., Rosengren, A., Tuomi, T., Wolk, A. & Carlsson, S., 2018, In : Diabetes & metabolism. 44, 4, p. 354-360 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

23 Me Res Team, IHGC, Gormley, P., Kurki, M. I., Hiekkala, M. E., Häppölä, P., Palta, P., Surakka, I., Kaunisto, M. A., Hämäläinen, E., Vepsäläinen, S., Havanka, H., Harno, H., Ilmavirta, M., Nissilä, M., Säkö, E., Sumelahti, M-L., Liukkonen, J., Sillanpaa, M., Metsähonkala, L. & 15 othersKoskinen, S., Lehtimaki, T., Raitakari, O., Männikko, M., Jousilahti, P., Anttila, V., Salomaa, V., Artto, V., Färkkilä, M., Daly, M. J., Neale, B. M., Ripatti, S., Kallela, M., Wessman, M. & Palotie, A., 16 May 2018, In : Neuron. 98, 4, p. 743–753 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

NHLBI TOPMED Lipids Working Grp, 23 Aug 2018, In : Nature Communications. 9, 12 p., 3391.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

NHLBI TOPMED Lipids Working Grp, 4 Jul 2018, In : Nature Communications. 9, 14 p., 2606.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

De novo variants in neurodevelopmental disorders with epilepsy

EuroEPINOMICS- RES Consortium, Heyne, H. O., Linnankivi, T., Palotie, A., Daly, M. J. & Lehesjoki, A-E., Jul 2018, In : Nature Genetics. 50, 7, p. 1048-1058 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Diabeetikon hoito päivystyksessä

Tuomi, T., 2018, Akuuttihoito-opas . Mäkijärvi, M., Harjola, V-P., Päivä, H., Valli, J. & Vaula, E. (eds.). 20. uud. p. ed. Helsinki: Kustannus Oy Duodecim, p. 397-399 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Diabetes

Tuomi, T., Antikainen, A., Honkasalo, M., Härmä-Rodriquez, S., Ilanne-Parikka, P., Meinander, T., Nuutinen, H., Rautavaara, M., Rautiainen, P., Suokas, J. & Tuomaala, A-K., 2018, In : Duodecim. 134, 9, p. 979-980 2 p.

Research output: Contribution to journalArticleProfessional

Open Access
File

Differences in the Commonly used Genotype Imputation Algorithms and Their Imputation Accuracy Estimates: 2018 IEEE 14th International Conference on e-Science

Pärn, K., Pirinen, M., Kals, M., Mägi, R., Salomaa, V., Boehnke, M., Hall, I., Stitziel, N., Freimer, N., Daly, M., Palotie, A., Ripatti, S. & Palta, P., 2018, p. 293-294. 2 p.

Research output: Conference materialsPaperResearchpeer-review

Do Disordered Eating Behaviours Have Long-term Health-related Consequences?

Karkkainen, U., Mustelin, L., Raevuori, A., Kaprio, J. & Keski-Rahkonen, A., Jan 2018, In : European Eating Disorders Review. 26, 1, p. 22-28 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Early maturation and substance use across adolescence and young adulthood: A longitudinal study of Finnish twins

Savage, J. E., Rose, R. J., Pulkkinen, L., Silventoinen, K., Korhonen, T., Kaprio, J., Gillespie, N. & Dick, D. M., Feb 2018, In : Development and Psychopathology. 30, 1, p. 79-92 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study

Neonatal Diabet Int Collaborative, Bowman, P. & Tuomi, T., Aug 2018, In : The Lancet diabetes & endocrinology. 6, 8, p. 637-646 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Efficient fine-mapping to identify causal genetic variants and quantify their contribution to complex phenotypes

Benner, C., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., Oct 2018, In : Genetic Epidemiology. 42, 7, p. 688-689 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Epigenetic DNA methylation changes associated with headache chronification: A retrospective case-control study

Int Headache Genetics Consortium, Feb 2018, In : Cephalalgia. 38, 2, p. 312-322 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Fecal Calprotectin Test Performed at Home: A Prospective Study of Pediatric Patients with Inflammatory Bowel Disease

Piekkala, M., Alfthan, H., Merras-Salmio, L., Puustinen Wikström, A., Heiskanen, K., Jaakkola, T., Klemetti, P., Färkkilä, M. & Kolho, K-L., Jun 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 66, 6, p. 926-931 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., Cook, J. P., Schmidt, E. M., Wuttke, M., Sarnowski, C., Magill, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M. H. & 95 othersPrins, B. P., Guo, X., Bielak, L. F., Below, J. E., Bowden, D. W., Chambers, J. C., Kim, Y. J., Ng, M. C. Y., Petty, L. E., Sim, X., Zhang, W., Bennett, A. J., Bork-Jensen, J., Brummett, C. M., Canouil, M., Kardt, K-U. E., Fischer, K., Kardia, S. L. R., Kronenberg, F., Lall, K., Liu, C-T., Locke, A. E., Luan, J., Ntalla, L., Nylander, V., Schoenherr, S., Schurmann, C., Yengo, L., Bottinger, E. P., Brandslund, I., Christensen, C., Dedoussis, G., Florez, J. C., Ford, I., France, O. H., Frayling, T. M., Giedraitis, V., Hackinger, S., Hattersley, A. T., Herder, C., Ikram, M. A., Ingelsson, M., Jorgensen, M. E., Jorgensen, T., Kriebel, J., Kuusisto, J., Ligthart, S., Lindgren, C. M., Linneberg, A., Lyssenko, V., Mamakou, V., Meitinger, T., Mohlke, K. L., Morris, A. D., Nadkarni, G., Pankow, J. S., Peters, A., Sattar, N., Stancakova, A., Strauch, K., Taylor, K. D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tuomilehto, J., Witte, D. R., Dupuis, J., Peyser, P. A., Zeggini, E., Loos, R. J. F., Froguel, P., Ingelsson, E., Lind, L., Groop, L., Laakso, M., Collins, F. S., Jukema, J. W., Palmer, C. N. A., Grallert, H., Metspalu, A., Dehghan, A., Koettgen, A., Abecasis, G. R., Meigs, J. B., Rotter, J., Marchini, J., Pedersen, O., Hansen, T., Langenberg, C., Wareham, N. J., Stefansson, K., Gloyn, A. L., Morris, A. P., Boehnke, M. & McCarthy, M., Nov 2018, In : Nature Genetics. 50, 11, p. 1505-+ 11 p.

Research output: Contribution to journalArticleScientificpeer-review

FinnGen-tutkimus luo perustaa genomitiedon hyödyntämiseksi terveydenhuollossa: Lähes joka kymmenes suomalainen osallistuu

Palotie, A., 2018, In : Duodecim. 134, 16, p. 1545-1547 3 p.

Research output: Contribution to journalEditorialProfessional

Open Access
File

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

Bone Mineral Density Childhood, Groop, L., Leslie, R. D. & Gran, S. F. A., Nov 2018, In : Diabetes Care. 41, 11, p. 2396-2403 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Gastroenterolgia ja Hepatologia

Färkkilä, M. (ed.), Heikkinen, M. (ed.), Isoniemi, H. (ed.) & Puolakkainen, P. (ed.), Jan 2018, 3. uud. p. ed. Helsinki: Kustannus Oy Duodecim. 1039 p.

Research output: Book/ReportBookProfessional

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

Social Science Genetic Association Consortium (SSGAC), COGENT (Cognitive Genomics Consortium), Lee, J. J., Wedow, R., Gupta, R., Latvala, A. E., Loukola, A-M., Kaprio, J. A., Kaasik, K., Lahti, J. M. T., Keltikangas-Järvinen, A. L., Räikkönen, K., Palotie, A. V., Sarin, A-P. J., Kaprio, J. A. & Eriksson, J. G., 23 Jul 2018, In : Nature Genetics. 50, 8, p. 1112-1121 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Million Vet Program, Oct 2018, In : Nature Genetics. 50, 10, p. 1412-+ 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis

The International PSC Study Group, The UK PSC Consortium, Alberts, R., de Vries, E. M. G., Goode, E. C., Jiang, X., Sampaziotis, F., Rombouts, K., Böttcher, K., Folseraas, T., Weismüller, T. J., Mason, A. L., Wang, W., Alexander, G., Alvaro, D., Bergquist, A., Björkström, N. K., Beuers, U., Björnsson, E., Boberg, K. M. & 56 othersBowlus, C. L., Bragazzi, M. C., Carbone, M., Chazouilleres, O., Cheung, A., Dalekos, G., Eaton, J., Eksteen, B., Ellinghaus, D., Färkkilä, M. A., Festen, E. A. M., Floreani, A., Franceschet, I., Gotthardt, D. N., Hirschfield, G. M., van Hoek, B., Holm, K., Hohenester, S., Hov, J. R., Imhann, F., Invernizzi, P., Juran, B. D., Lenzen, H., Lieb, W., Liu, J. Z., Marschall, H-U., Marzioni, M., Melum, E., Milkiewicz, P., Müller, T., Pares, A., Rupp, C., Rust, C., Sandford, R. N., Schramm, C., Schreiber, S., Schrumpf, E., Silverberg, M. S., Srivastava, B., Sterneck, M., Teufel, A., Vallier, L., Verheij, J., Vila, A. V., de Vries, B., Zachou, K., Chapman, R. W., Manns, M. P., Pinzani, M., Rushbrook, S. M., Lazaridis, K. N., Franke, A., Anderson, C. A., Karlsen, T. H., Ponsioen, C. Y. & Weersma, R. K., 2018, In : Gut. 67, 8, p. 1517-1524 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic Associations With Gestational Duration and Spontaneous Preterm Birth

Zhang, G., Feenstra, B., Bacelis, J., Liu, X., Muglia, L. M., Juodakis, J., Miller, D. E., Litterman, N., Jiang, P-P., Russell, L., Hinds, D. A., Hu, Y., Weirauch, M. T., Chen, X., Chavan, A. R., Wagner, G. P., Pavlicev, M., Nnamani, M. C., Maziarz, J., Karjalainen, M. K. & 18 othersRamet, M., Sengpiel, V., Geller, F., Boyd, H. A., Palotie, A., Momany, A., Bedell, B., Ryckman, K. K., Huusko, J. M., Forney, C. R., Kottyan, L. C., Hallman, M., Teramo, K., Nohr, E. A., Smith, G. D., Melbye, M., Jacobsson, B. & Muglia, L. J., Feb 2018, In : Obstetrical & Gynecological Survey. 73, 2, p. 83-85 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic determinants of glucose levels in pregnancy: genetic risk scores analysis and GWAS in the Norwegian STORK cohort

Moen, G-H., LeBlanc, M., Sommer, C., Prasad, R. B., Lekvas, T., Normann, K. R., Qvigstad, E., Groop, L., Birkeland, K., Evans, D. M. & Froslie, K. F., Dec 2018, In : European Journal of Endocrinology. 179, 6, p. 363-372 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

Gusarova, V., O'Dushlaine, C., Teslovich, T. M., Benotti, P. N., Mirshahi, T., Gottesman, O., Van Hout, C. V., Murray, M. F., Mahajan, A., Nielsen, J. B., Fritsche, L., Wulff, A. B., Gudbjartsson, D. F., Sjogren, M., Emdin, C. A., Scott, R. A., Lee, W-J., Small, A., Kwee, L. C., Dwivedi, O. P. & 31 othersPrasad, R. B., Bruse, S., Lopez, A. E., Penn, J., Marcketta, A., Leader, J. B., Still, C. D., Kirchner, H. L., Mirshahi, U. L., Wardeh, A. H., Hartle, C. M., Habegger, L., Fetterolf, S. N., Tusie-Luna, T., Morris, A. P., Holm, H., Steinthorsdottir, V., Sulem, P., Thorsteinsdottir, U., Rotter, J. I., Chuang, L-M., Damrauer, S., Birtwell, D., Brummett, C. M., Khera, A. V., Natarajan, P., Orho-Melander, M., Flannick, J., Lotta, L. A., Hansson, O. & Groop, L., 13 Jun 2018, In : Nature Communications. 9, 11 p., 2252.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Genetics of migraine

Anttila, V., Wessman, M., Kallela, M. & Palotie, A., 2018, Handbook of Clinical Neurology: Neurogenetics, Part II. Geschwind, D. H., Paulson, H. L. & Klein, C. (eds.). 1st ed. ed. Elsevier, Vol. 148. p. 493-503 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Genetics Sheds New Light on Congenital Hydrocephalus Biology

Lal, D. & Palotie, A., 25 Jul 2018, In : Neuron. 99, 2, p. 246-247 2 p.

Research output: Contribution to journalEditorialScientificpeer-review

Genetic variation in VAC14 is associated with bacteremia secondary to diverse pathogens in African children

Wellcome Trust Case-Control Conso & Kenyan Bacteraemia Study Grp, 17 Apr 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 16, p. E3601-E3603 3 p.

Research output: Contribution to journalLetterScientificpeer-review

Open Access

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

Xue, A., Wu, Y., Zhu, Z., Zhang, F., Kemper, K. E., Zheng, Z., Yengo, L., Lloyd-Jones, L. R., Sidorenko, J., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Awadalla, P., Battle, A., Beutner, F., Bonder, M. J., Boomsma, D., Christiansen, M., Claringbould, A. & 62 othersDeelen, P., Esko, T., Favé, M-J., Franke, L., Frayling, T., Gharib, S., Gibson, G., Hemani, G., Jansen, R., Kähönen, M., Kalnapenkis, A., Kasela, S., Kettunen, J., Kim, Y., Kirsten, H., Kovacs, P., Krohn, K., Kronberg-Guzman, J., Kukushkina, V., Kutalik, Z., Lee, B., Lehtimäki, T., Loeffler, M., Marigorta, U. M., Metspalu, A., Milani, L., Müller-Nurasyid, M., Nauck, M., Nivard, M., Penninx, B., Perola, M., Pervjakova, N., Pierce, B., Powell, J., Prokisch, H., Psaty, B., Raitakari, O., Ring, S., Ripatti, S., Rotzschke, O., Ruëger, S., Saha, A., Scholz, M., Schramm, K., Seppälä, I., Stumvoll, M., Sullivan, P., Teumer, A., Thiery, J., Tong, L., Tönjes, A., van Dongen, J., van Meurs, J., Verlouw, J., Völker, U., Võsa, U., Yaghootkar, H., Zeng, B., McRae, A. F., Visscher, P. M., Zeng, J. & Yang, J., 2018, In : Nature Communications. 9, 1, 14 p., 2941.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

Savage, J. E., Jansen, P. R., Stringer, S., Watanabe, K., Bryois, J., de Leeuw, C. A., Nagel, M., Awasthi, S., Barr, P. B., Coleman, J. R. I., Grasby, K. L., Hammerschlag, A. R., Kaminski, J. A., Karlsson, R., Krapohl, E., Lam, M., Nygaard, M., Reynolds, C. A., Trampush, J. W., Young, H. & 97 othersZabaneh, D., Hagg, S., Hansell, N. K., Karlsson, I. K., Linnarsson, S., Montgomery, G. W., Munoz-Manchado, A. B., Quinlan, E. B., Schumann, G., Skene, N. G., Webb, B. T., White, T., Arking, D. E., Avramopoulos, D., Bilder, R. M., Bitsios, P., Burdick, K. E., Cannon, T. D., Chiba-Falek, O., Christoforou, A., Cirulli, E. T., Congdon, E., Corvin, A., Davies, G., Deary, I. J., DeRosse, P., Dickinson, D., Djurovic, S., Donohoe, G., Conley, E. D., Eriksson, J. G., Espeseth, T., Freimer, N. A., Giakoumaki, S., Giegling, I., Gill, M., Glahn, D. C., Hariri, A. R., Hatzimanolis, A., Keller, M. C., Knowles, E., Koltai, D., Konte, B., Lahti, J., Le Hellard, S., Lencz, T., Liewald, D. C., London, E., Lundervold, A. J., Malhotra, A. K., Melle, I., Morris, D., Need, A. C., Ollier, W., Palotie, A., Payton, A., Pendleton, N., Poldrack, R. A., Räikkönen, K., Reinvang, I., Roussos, P., Rujescu, D., Sabb, F. W., Scult, M. A., Smeland, O. B., Smyrnis, N., Starr, J. M., Steen, V. M., Stefanis, N. C., Straub, R. E., Sundet, K., Tiemeier, H., Voineskos, A. N., Weinberger, D. R., Widen, E., Yu, J., Abecasis, G., Andreassen, O. A., Breen, G., Christiansen, L., Debrabant, B., Dick, D. M., Heinz, A., Hjerling-Leffler, J., Ikram, M. A., Kendler, K. S., Martin, N. G., Medland, S. E., Pedersen, N. L., Plomin, R., Polderman, T. J. C., Ripke, S., van der Sluis, S., Sullivan, P. F., Vrieze, S. I., Wright, M. J. & Posthuma, D., Jul 2018, In : Nature Genetics. 50, 7, p. 912-+ 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

Tanskanen, T., van den Berg, L., Valimaki, N., Aavikko, M., Ness-Jensen, E., Hveem, K., Wettergren, Y., Lindskog, E. B., Tonisson, N., Metspalu, A., Silander, K., Orlando, G., Law, P. J., Tuupanen, S., Gylfe, A. E., Hanninen, U. A., Cajuso, T., Kondelin, J., Sarin, A-P., Pukkala, E. & 40 othersJousilahti, P., Salomaa, V., Ripatti, S., Palotie, A., Jarvinen, H., Renkonen-Sinisalo, L., Lepisto, A., Bohm, J., Mecklin, J-P., Al-Tassan, N. A., Palles, C., Martin, L., Barclay, E., Tenesa, A., Farrington, S. M., Timofeeva, M. N., Meyer, B. F., Wakil, S. M., Campbell, H., Smith, C. G., Idziaszczyk, S., Maughan, T. S., Kaplan, R., Kerr, R., Kerr, D., Buchanan, D. D., Win, A. K., Hopper, J., Jenkins, M. A., Newcomb, P. A., Gallinger, S., Conti, D., Schumacher, F. R., Casey, G., Cheadle, J. P., Dunlop, M. G., Tomlinson, I. P., Houlston, R. S., Palin, K. & Aaltonen, L. A., 1 Feb 2018, In : International Journal of Cancer. 142, 3, p. 540-546 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

Jiang, X., O'Reilly, P. F., Aschard, H., Hsu, Y-H., Richards, J. B., Dupuis, J., Ingelsson, E., Karasik, D., Pilz, S., Berry, D., Kestenbaum, B., Zheng, J., Luan, J., Sofianopoulou, E., Streeten, E. A., Albanes, D., Lutsey, P. L., Yao, L., Tang, W., Econs, M. J. & 84 othersWallaschofski, H., Voelzke, H., Zhou, A., Power, C., McCarthy, M. I., Michos, E. D., Boerwinkle, E., Weinstein, S. J., Freedman, N. D., Huang, W-Y., Van Schoor, N. M., van der Velde, N., de Groot, L. C. P. G. M., Enneman, A., Cupples, L. A., Booth, S. L., Vasan, R. S., Liu, C-T., Zhou, Y., Ripatti, S., Ohlsson, C., Vandenput, L., Lorentzon, M., Eriksson, J. G., Shea, M. K., Houston, D. K., Kritchevsky, S. B., Liu, Y., Lohman, K. K., Ferrucci, L., Peacock, M., Gieger, C., Beekman, M., Slagboom, E., Deelen, J., van Heemst, D., Kleber, M. E., Maerz, W., de Boer, I. H., Wood, A. C., Rotter, J. I., Rich, S. S., Robinson-Cohen, C., den Heijer, M., Jarvelin, M-R., Cavadino, A., Joshi, P. K., Wilson, J. F., Hayward, C., Lind, L., Michaelsson, K., Trompet, S., Zillikens, M. C., Uitterlinden, A. G., Rivadeneira, F., Broer, L., Zgaga, L., Campbell, H., Theodoratou, E., Farrington, S. M., Timofeeva, M., Dunlop, M. G., Valdes, A. M., Tikkanen, E., Lehtimaki, T., Lyytikainen, L-P., Kahonen, M., Raitakari, O. T., Mikkila, V., Ikram, M. A., Sattar, N., Jukema, J. W., Wareham, N. J., Langenberg, C., Forouhi, N. G., Gundersen, T. E., Khaw, K-T., Butterworth, A. S., Danesh, J., Spector, T., Wang, T. J., Hypponen, E., Kraft, P. & Kiel, D. P., 17 Jan 2018, In : Nature Communications. 9, 12 p., 260.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

Int League Against Epilepsy Conso, Abou-Khalil, B., Eriksson, J. G., Lehesjoki, A-E. & Palotie, A., 10 Dec 2018, In : Nature Communications. 9, 15 p., 5269.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File