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Publications 1969 2019

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Meeting Abstract
2019

Injury Severity and Extracranial Injuries Are Associated with Delayed Return to Work in Mild Traumatic Brain Injury Patients

Huovinen, A., Isokuortti, H., Marinkovic, I., Vanni, S. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 128-129 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Intracranial Traumatic Lesions Delay Return to Work in Mild Traumatic Injury Patients

Huovinen, A., Marinkovic, I., Isokuortti, H., Korvenoja, A., Vanni, S. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 130-131 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Psychiatric Disorders and Return to Work after Mild Traumatic Brain Injury

Marinkovic, I., Isokuortti, H., Huovinen, A., Korvenoja, A., Vataja, R. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 153-153 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2018

(242) - Donor Plasma VEGF as a Biomarker for Early Graft Failure After Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Holmström, E., Tuuminen, R., Krebs, R., Rouvinen, E., Nykänen, A. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S103

Research output: Contribution to journalMeeting AbstractResearchpeer-review

(245) - Proinflammatory Cytokines as Biomarkers for Severe Primary Graft Dysfunction After Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Holmström, E., Tuuminen, R., Syrjälä, S., Krebs, R., Rouvinen, E., Nykänen, A. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S104

Research output: Contribution to journalMeeting AbstractResearchpeer-review

(348) - Worldwide Experience of Adult Patients with Small Body Size Supported by a Continuous-Flow Left Ventricular Assist Device - An IMACS Analysis: ISHLT 38th Annual Meeting and Scientific Sessions

Lee, S., Xie, R., Lemstrom, K., Dickinson, M. G., Boeve, T., Leacche, M., Cowger, J., de By, T. & Kirklin, J. K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S145 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Cardiovascular autonomic function after simultaneous pancreas-kidney and kidney-alone transplantation in patients with diabetes

Paajanen, H., Bordino, M., Sandelin, A., Ekstrand, A., Lempinen, M., Forsblom, C., Bernardi, L. & Groop, P-H., 2018, (Accepted/In press) In : Diabetes Care. 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Combined Targeting of BET Family Proteins and BCL2 Is Synergistic in Acute Myeloid Leukemia Cells Overexpressing S100A8 and S100A9

Karjalainen, R., Liu, M., Kumar, A., Parsons, A., He, L., Malani, D. R., Kontro, M., Porkka, K. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Donor Simvastatin Treatment Alters Protein Expression in the Recipient after Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Lukac, J., Holmström, E., Joenväärä, S., Saraswat, M., Krebs, R., Tohmola, T., Nykänen, A., Renkonen, R. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, p. S169-S170 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Efficient fine-mapping to identify causal genetic variants and quantify their contribution to complex phenotypes

Benner, C., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., Oct 2018, In : Genetic Epidemiology. 42, 7, p. 688-689 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Enantiospecific Pharmacogenomics of Fluvastatin

Hirvensalo, P., Tornio, A., Neuvonen, M., Kiander, W., Kidron, H., Paile-Hyvärinen, M., Tapaninen, T., Backman, J. & Niemi, M., May 2018, In : Basic & Clinical Pharmacology & Toxicology. 123, p. 7-7 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Epidemiology, genetic models and epigenetics of insomnia

Paunio, T., Sep 2018, In : Journal of Sleep Research. 27, 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Genome-Scale CRISPR Screens Identify Essential Genes for Sensitivity to Natural Killer Cells in Hematological Malignancies

Dufva, O., Klievink, J., Saeed, K., Kankainen, M., Ilander, M., Hannunen, T., Lagstrom, S., Ellonen, P., Lee, D. A. & Mustjoki, S., 29 Nov 2018, In : Blood. 132, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Late Breaking Abstract - Conversion of FENO from different flows to the standard flow.

Lassmann-Klee, P., Lehtimaki, L., Lindholm, T., Malmberg, P., Sovijarvi, A. & Piirila, P., 15 Sep 2018, In : European Respiratory Journal. 52, Suppl 62, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Melatonin receptor type 1A gene linked to intolerance to shift work and Alzheimer's disease in old age

Sulkava, S., Muggalla, P., Sulkava, R., Ollila, H. M., Peuralinna, T., Myllykangas, L., Helisalmi, S., Soininen, H., Polvikoski, T., Hiltunen, M., Tienari, P. J., Huttunen, H. J. & Paunio, T., Sep 2018, In : Journal of Sleep Research. 27, Supplement 1, 1 p., P007.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Multi-Parametric Single Cell Profiling Defines Distinct Drug Responses in Healthy Hematological Cell Lineages That Are Retained in Corresponding Malignant Cell Types

Majumder, MM., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Bazou, D., Andersson, E. I., Parsons, A., Tang, J., Kallioniemi, O-P., Mustjoki, S. M., O'Gorman, P., Wennerberg, J. K., Porkka, K. V. K., Gjertsen, B-T. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Novel mutations in fibronectin associated with metaphyseal fractures - Expanding the phenotype of patients with a subtype of spondylomethaphyseal dysplasia with "corner fractures"

Alm, J. J., Costantini, A., Valta, H., Baratang, N. V., Yap, P., Bertola, D., Yamamoto, G., Kim, C. A., Chen, J., Wierenga, K. J., Fanning, E. A., Escobar, L., Mcwalter, K., Mclaughlin, H., Willaert, R., Begtrup, A., Reinhardt, D. P., Makitie, O. & Campeau, P. M., Nov 2018, In : Journal of Bone and Mineral Research. 33, p. 417-417 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Oncolytic Adenoviruses Encapsulated into the Extracellular Vesicles as Carriers for Cancer Drug Delivery

Garofalo, M., Saari, H., Somersalo, P., Crescenti, D., Kuryk, L., Aksela, L., Capasso, C., Madetoja, M., Koskinen, K., Makitie, A., Jalasvuori, M., Cerullo, V., Ciana, P. & Yliperttula, M., May 2018, In : Molecular therapy. 26, 5, p. 203-203 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Somatic Mutations in CD8+T Cells in Patients with Chronic Immune Thrombocytopenia Are Associated with Increased Clonality and Cytotoxic Phenotype of CD8+T Cells

Rajala, H., Savola, P., Lundgren, S., Eldfors, S., Kelkka, T., Ebeling, F. & Mustjoki, S., 29 Nov 2018, In : Blood. 132, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

What's in a shopping basket? Alcohol and grocery purchases among Finnish loyalty-card holders

Uusitalo, P. L., Erkkola, M., Lintonen, T., Rahkonen, O. & Nevalainen, J., Nov 2018, In : European Journal of Public Health. 28, suppl_4, p. 140-140 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2017

Changes in risky alcohol use and sickness absence

Ervasti, J., Kivimäki, M., Pentti, J., Halonen, J. I., Vahtera, J. & Virtanen, M., Nov 2017, In : European Journal of Public Health. 27, suppl. 3, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Characterization of Immunological Profiles with Clinical Significance in Patients with Classical Hodgkin Lymphoma

Karihtala, K., Leivonen, S-K., Karjalainen-Lindsberg, M-L. & Leppa, S., 7 Dec 2017, In : Blood. 130, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CHILDHOOD ADVERSITY, ADULT SOCIOECONOMIC STATUS AND RISK OF WORK DISABILITY - A PROSPECTIVE COHORT STUDY

Kivimaki, M., Vahtera, J., Pentti, J., Virtanen, M., Ervasti, J. & Lallukka, T., Sep 2017, In : Journal of Epidemiology & Community Health. 71, Suppl. 1, p. A61-A61 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CHRONIC MYELOID LEUKEMIA PATIENTS WERE NOT DIFFERENT IN MOLECULAR RELAPSE AFTER STOPPING IMATINIB IN MR4 WHETHER RESIDUAL DISEASE WAS DETECTED OR NOT - WHEN ADJUSTING FOR NUMBER OF CONTROL TRANSCRIPTS

Pfirrmann, M., Mahon, F-X., Guilhot, J., Richter, J., Almeida, A., Janssen, J. J., Mayer, J., Koskenvesa, P., Panayiotidis, P., Olsson-Stromberg, U., Berger, M. G., Diamond, J., Ehrencrona, H., Kairisto, V., Polakova, K. M., Mueller, M. C., Mustjoki, S., Hochhaus, A., Saussele, S. & Hjorth-Hansen, H., 26 Jun 2017, In : Haematologica. 102, p. 153-153 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CLINICAL AND IMMUNOLOGICAL EFFECTS OF NILOTINIB IN COMBINATION WITH PEGYLATED INTERFERON-A2B IN PATIENTS WITH SUBOPTIMAL MOLECULAR RESPONSE ON IMATINIB (NORDDUTCHCML009)

Geelen, I., Olsson-Stromberg, U., Mustjoki, S., Richter, J., Blijlevens, N., Smit, W., Gjertsen, B., Gedde-Dahl, T., Markevarn, B., Koppes, M., Westerweel, P., Janssen, J. & Hjorth-Hansen, H., 26 Jun 2017, In : Haematologica. 102, p. 435-435 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Copanlisib (COP) in patients with relapsed or refractory indolent B-cell lymphoma: primary results of the pivotal Chronos-1 study

Dreyling, M., Santoro, A., Mollica, L., Leppa, S., Follows, G. A., Lenz, G., Kim, W. S., Nagler, A., Panayiotidis, P., Demeter, J., Ozcan, M., Kosinova, M., Bouabdallah, K., Morschhauser, F., Stevens, D. A., Trevarthen, D., Giurescu, M., Kupit, L., Childs, B. H. & Zinzani, P. L., Sep 2017, In : Oncology research and treatment. 40, p. 12-12 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Copanlisib in patients with relapsed or refractory follicular lymphoma.

Dreyling, M. H., Santoro, A., Leppa, S., Demeter, J., Follows, G., Lenz, G., Kim, W. S., Mollica, L., Nagler, A., Diong, C. P., Provencio, M., Stevens, D. A., Trevarthen, D., Magagnoli, M., Cupit, L., Yin, S., Hiemeyer, F., -Vargas, J. E. G., Childs, B. H. & Zinzani, P. L., 20 May 2017, In : Journal of Clinical Oncology. 35, 5 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Copanlisib treatment in patients with relapsed or refractory indolent B-cell lymphoma: Subgroup analyses from the CHRONOS-1 study

Provencio Pulla, M., Santoro, A., Mollica, L., Leppa, S., Follows, G., Lenz, G., Kim, W. S., Nagler, A., Panayiotidis, P., Demeter, J., Ozcan, M., Kosinova, M., Bouabdallah, K., Morschhauser, F., Ishida, T., Huang, L., Garcia-Vargas, J., Childs, B. H., Zinzani, P. L. & Dreyling, M., Sep 2017, In : Annals of Oncology. 28, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

DISC1 GENE NETWORK MUTATIONS IN MAJOR MENTAL ILLNESS

Sinha, V., Ortega-Alonso, A., Ukkola-Vuoti, L., Hovatta, I., Haukka, J., Torniainen, M., Therman, S., Cannon, T., Kaprio, J., Lonnqvist, J., Partonen, T., Isometsa, E., Paunio, T., Suvisaari, J. & Hennah, W., Oct 2017, In : European Neuropsychopharmacology. 27, p. S406-S407 2 p., M57.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Effect of Reference Panel in ID Score Regression Analysis of Lipid Traits in the Finnish Population

Hautakangas, H., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., 2017, In : Human Heredity. 83, 1, p. 10-10 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

EFFICACY AND SAFETY OF COPANLISIB IN PATIENTS WITH RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA: A SUBSET ANALYSIS OF THE CHRONOS-1 STUDY

Zinzani, P. L., Santoro, A., Leppa, S., Demeter, J., Follows, G. A., Lenz, G., Kim, W. S., Mollica, L., Nagler, A., Diong, C. P., Provenciio, M., Stevens, D. A., Trevarthen, D., Maagnoli, M., Cupit, L., Yin, S., Hiemeyer, F., Garcia-Vargas, J., Childs, B. H. & Dreyling, M., 26 Jun 2017, In : Haematologica. 102, p. 314-315 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Epigenetic clock at birth and psychiatric problems during early childhood

Suarez, A., Lahti, J., Czamara, D., Lahti, M., Knight, A. K., Girchenko, P., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Smith, A. K., Binder, E. B. & Räikkönen, K., Sep 2017, In : Psychoneuroendocrinology. 83S, p. 52-52 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Open Access
File

Evaluating Robustness and Geographic Differences in Polygenic Risk in Finland

Kerminen, S., Koskela, J., Havulinna, A. S., Surakka, I., Martin, A. R., Palotie, A., Perola, M., Salomaa, V., Daly, M. J., Ripatti, S. & Pirinen, M., 2017, In : Human Heredity. 83, 1, p. 14-14 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Turkki, R., Bychkov, D., Linder, N., Isola, J., Joensuu, H. T. & Lundin, J., 1 Jul 2017, In : Cancer Research. 77, 13 Supplement, p. 673 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

High Amount of PD-L1+Tumor Associated Macrophages Is Associated with Better Survival in Patients with Primary Testicular Lymphoma

Pollari, M., Bruck, O., Leivonen, S-K., Pellinen, T., Vahamurto, P., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, Suppl 1, p. Meeting Abstract: 2761 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Higher mortality in adult-onset asthma: a 15 year follow-up of a population-based matched cohort

Lemmetyinen, R., Karjalainen, J., But, A., Renkonen, R., Pekkanen, J., Haukka, J. & Toppila-Salmi, S., Aug 2017, In : Allergy : European journal of allergy and clinical immunology. 72, p. 391-391 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 Jun 2017, In : Haematologica. 102, p. 654-654 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

INCREASED INDOLEAMINE 2,3-DIOXYGENASE (IDO1) ACTIVITY IN EARLY CHRONIC PHASE CHRONIC MYELOGENOUS LEUKEMIA (CML-CP) IS REDUCED BY NILOTINIB THERAPY AND PREDICTS MOLECULAR RESPONSE

Sopper, S., Mustjoki, S., Gastl, G., Trajanoski, Z., Giles, F., Hochhaus, A., Janssen, J., Geisler, S., Fuchs, D. & Wolf, D., 26 Jun 2017, In : Haematologica. 102, p. 232-233 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Indoleamine 2,3-Dioxygenase (Ido1) activity is increased in early chronic phase Chronic Myelogenous Leukemia (CML) and predicts molecular response to nilotinib therapy

Sopper, S., Mustjoki, S., Geisler, S., Fuchs, D., Hackl, H., Trajanoski, Z., Hochhaus, A. & Wolf, D., Dec 2017, In : European Journal of Immunology. 47, p. 170-170 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low Expression of T/NK-Cell Signature Predicts Poor Survival in Patients with Primary Testicular and Diffuse Large B-Cell Lymphoma

Leivonen, S-K., Pollari, M., Bruck, O., Pellinen, T., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

LOW IL-2 CONCENTRATION FAVORS GENERATION OF EARLY MEMORY T CELLS OVER TERMINAL EEFECTORS DURING CAR T-CELL EXPANSION

Luostarinen, A., Kaartinen, T., Maliniernii, P., Keto, J., Arvas, M., Belt, H., Koponen, J., Loskog, A., Mustjoki, S., Porkka, K., Yla-Herttuala, S. & Korhonen, M., May 2017, In : Cytotherapy. 19, 5, p. S8-S8 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

NATURAL HISTORY OF CERVICAL INTRAEPITHELIAL NEOPLASIA GRADE 2 UNDER ACTIVE SURVEILLANCE - A SYSTEMATIC REVIEW AND META-ANALYSIS

Tainio, K., Athanasiou, A., Tikkinen, K., Aaltonen, R., Cardenas Hernandes, L., Glazer-Livson, S., Jakobsson, M., Joronen, K., Kiviharju, M., Louvanto, K., Oksjoki, S., Tahtinen, R., Virtanen, S., Nieminen, P., Kyrgiou, M. & Kalliala, I., Nov 2017, In : International Journal of Gynecological Cancer. 27, p. 25-25 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

PAIN AND ROUTES OF EXIT OUT OF PAID EMPLOYMENT AMONG BRITISH CIVIL SERVANTS: A FOLLOW-UP STUDY 1985-2013

Lallukka, T. L., Manty, M. M., Cooper, C. C., Fleischmann, M. F., Kouvonen, A. K., Head, J. H. & Halonen, J. I. H., Sep 2017, In : Journal of Epidemiology & Community Health. 71, Suppl.1, p. A75-A76 2 p., P55.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

PHENOTYPIC TRANSLATION OF THE DISC1 NETWORK HIGHLIGHTS THE ROLE OF THE NDE1 LOCUS, WITH PHARMACOLOGICAL IMPLICATIONS

Hennah, W., Bradshaw, N., Pankakoski, M., Ortega-Alonso, A., Torniainen, M., Paunio, T., Suvisaari, J., Lonnqvist, J. & Haukka, J., Oct 2017, In : European Neuropsychopharmacology. 27, p. S510-S511 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Representational similarity analysis of EEG and fMRI responses to face identities and emotional expressions

Ölander, K., Muukkonen, I., Numminen, J. & Salmela, V., 2017, In : Journal of Vision. 17, 10, p. 271 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
File

ST-segment elevation in baseline electrocardiogram predicts mortality in cardiogenic shock

Javanainen, T. S., Tolppanen, HEV., Harjola, VP., Lassus, J., Tarvasmäki, T., Nieminen, MS., Spinar, J., Sionis, A., Banaszewski, M. & Jurkko, R., 2017, In : European Journal of Heart Failure. 19, p. 216-217 2 p., P939.

Research output: Contribution to journalMeeting AbstractResearch

TELOMERE SHORTENING IN CD34+38-BCR-ABL POSITIVE BONE MARROW CELLS FROM NEWLY DIAGNOSED PATIENTS WITH CML CORRELATES WITH THE CLONE SIZE OF THE LEUKEMIC STEM CELL COMPARTMENT

Bouillon, A. -S., Ferreira, M. V., Awad, S. A., Richter, J., Hjorth-Hansen, H., Hummel, S., Schemionek, M., Mustjoki, S., Beier, F. & Bruemmendorf, T. H., 26 Jun 2017, In : Haematologica. 102, p. 231-232 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Th1/2 Immune Response Signature Predicts Outcome after Dose-Dense Immunochemotherapy in Patients with High Risk Diffuse Large B-Cell Lymphoma - Results from Nordic Lymphoma Group Trials

Autio, M., Leivonen, S-K., Jorgensen, J. M., Karjalainen-Lindsberg, M-L., Beiske, K., Holte, H. & Leppä, S., 7 Dec 2017, In : Blood. 130, 2 p., 4008.

Research output: Contribution to journalMeeting AbstractResearchpeer-review