Projects per year
Organization profile
Organisation Profile
The Ripatti group studies genome-wide variation and its relation to complex traits and diseases, with a particular focus, but not limited to, on cardiovascular diseases and metabolism. We build on our understanding of genome-wide variation, Finnish genetically and epidemiologically well-profiled cohorts and knowledge and development of statistical and computational tools, and aim at identifying variants, genes and genetic loci modifying complex disease risks. We also study ways to translate the findings into potential intervention targets and comprehensive disease risk assessments.
International and National Collaboration
Publications and projects within past five years.
Profiles
Paavo Häppölä
- Complex Disease Genetics
- Genomics of Neurological and Neuropsychiatric Disorders
- Institute for Molecular Medicine Finland - Bioinformatician
- Doctoral Programme in Population Health
Person: M5 Teaching and research support staff
Shabbeer Hassan
- Complex Disease Genetics
- Institute for Molecular Medicine Finland - Doctoral Student
- Doctoral Programme in Population Health
Person: U1 Research and teaching staff
Aki Havulinna
- Complex Disease Genetics
- Institute for Molecular Medicine Finland - Senior Researcher
- Staff Services - Title of Docent
Person: U3 Research and teaching staff
Pyry Helkkula
- Complex Disease Genetics
- Institute for Molecular Medicine Finland - Doctoral Student
- Doctoral Programme in Population Health
Person: U1 Research and teaching staff
Mart Kals
- Complex Disease Genetics
- Institute for Molecular Medicine Finland - Postdoctoral Researcher
Person: U2 Teaching and research staff
Projects 2010 2019
Finngen: FinnGen
Palotie, A., Pitkänen, K., Jalanko, A., Lyhs, U., Donner, K. M., Kaunisto, M., Kurki, M. I., Kristiansson, K., Laiho, P., Laivuori, H., Loukola, A., Palta, P., Perola, M., Kajanne, R., Harju, J. J. & Havulinna, A.
15/08/2017 → …
Project: Research project
Department of Public Health, University of Helsinki
Wedenoja, J., Kaprio, J., Loukola, A., Korhonen, T., Hällfors, J., Heikkilä, K., Ripatti, S. & Tikkanen, E.
01/04/2011 → …
Project: Research project
Persinalized disease risk assessment platform
Palta, P., Häppölä, P. & Koskela, J.
01/06/2018 → 31/12/2019
Project: Research project
ePerMed: Rise of scientific excellence and collaboratio for implementing personalised medicine in Estonia
01/01/2016 → 31/12/2018
Project: Other project
Publications 2010 2020
Genomic prediction of alcohol-related morbidity and mortality
Kiiskinen, T., Mars, N., Palviainen, T., Koskela, J., Rämö, J., Ripatti, P., Ruotsalainen, S., Project, F., GSCAN Consortium, Palotie, A., Madden, P. A. F., Rose, R. J., Kaprio, J., Salomaa, V., Mäkelä, P., Havulinna, A. & Ripatti, S., 21 Jan 2020, In : Translational Psychiatry.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study
Lindbohm, J., Sipilä, P. N., Mars, N. J., Pentti, J., Ahmadi-Abhari, S., Brunner, E. J., Shipley, M. J., Singh-Manoux, A., Tabak, A. G. & Kivimäki, M., Apr 2019, In : The Lancet Public Health. 4, 4, p. E189-E199 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Association analyses identify 31 new risk loci for colorectal cancer susceptibility
PRACTICAl Consortium, Law, P. J., Timofeeva, M., Fernandez-Rozadilla, C., Palin, K., Hänninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Eriksson, J. G., Jousilahti, P., Ripatti, S., Palotie, A., Renkonen-Sinisalo, L., Lepistö, A., Aaltonen, L. A., Rissanen, H., Salomaa, V. & 3 others, , 14 May 2019, In : Nature Communications. 10, 15 p., 2154.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease
IBD Pharmacogenetics Study Grp, Walker, G. J., Harrison, J. W., Daly, M. J. & Koskela, J., 26 Feb 2019, In : JAMA : The Journal of the American Medical Association. 321, 8, p. 773-785 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts
Ahola-Olli, A. V., Mustelin, L., Kalimeri, M., Kettunen, J., Jokelainen, J., Auvinen, J., Puukka, K., Havulinna, A. S., Lehtimäki, T., Kähönen, M., Juonala, M., Keinänen-Kiukaanniemi, S., Salomaa, V., Perola, M., Järvelin, M-R., Ala-Korpela, M., Raitakari, O. & Wurtz, P., Dec 2019, In : Diabetologia. 62, 12, p. 2298-2309 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Activities 2007 2019
Novo Nordisk Foundation Center for Basic Metabolic Research Platform (Event)
Samuli Ripatti (Board member)27 May 2019 → 28 May 2019
Activity: Membership types › Membership or other role in national/international committee, council, board
New England Journal of Medicine (Journal)
Samuli Ripatti (Reviewer)22 Jan 2019
Activity: Publication peer-review and editorial work types › Peer review of manuscripts
Cell (Journal)
Samuli Ripatti (Reviewer)1 Feb 2019
Activity: Publication peer-review and editorial work types › Peer review of manuscripts
Lecture: We have the polygenic risks - but do they matter in prevention?
Samuli Ripatti (Speaker)7 Feb 2019 → 8 Feb 2019
Activity: Talk or presentation types › Oral presentation
Primary GWAS plan & schedule
Samuli Ripatti (Speaker)12 Apr 2019
Activity: Talk or presentation types › Oral presentation