Projects per year
Organisation profile
Organisation Profile
The Ripatti group studies genome-wide variation and its relation to complex traits and diseases, with a particular focus, but not limited to, on cardiovascular diseases and metabolism. We build on our understanding of genome-wide variation, Finnish genetically and epidemiologically well-profiled cohorts and knowledge and development of statistical and computational tools, and aim at identifying variants, genes and genetic loci modifying complex disease risks. We also study ways to translate the findings into potential intervention targets and comprehensive disease risk assessments.
International and National Collaboration
Profiles
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Paavo Häppölä
- Institute for Molecular Medicine Finland - Bioinformatician
- Complex Disease Genetics
- Genomics of Neurological and Neuropsychiatric Disorders
Person: M5 Teaching and research support staff
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Aki Havulinna
- Medicum - Title of Docent
- Institute for Molecular Medicine Finland - Senior Researcher
- Complex Disease Genetics
Person: U3 Research and teaching staff
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Tuomo Kiiskinen, MD
- Institute for Molecular Medicine Finland - Postdoctoral Researcher
- Complex Disease Genetics
- Genomics of Neurological and Neuropsychiatric Disorders
Person: U1 Research and teaching staff, U2 Teaching and research staff
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Jukka Koskela
- Institute for Molecular Medicine Finland - Senior Researcher
- Complex Disease Genetics
- Doctoral Programme in Population Health - Supervisor for doctoral programme
Person: U3 Research and teaching staff, U2 Teaching and research staff
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Finngen: FinnGen
Palotie, A., Pitkänen, K., Jalanko, A., Lyhs, U., Donner, K. M., Kaunisto, M., Kurki, M. I., Kristiansson, K., Laiho, P., Laivuori, H., Loukola, A., Palta, P., Perola, M., Kajanne, R., Harju, J. J. & Havulinna, A.
15/08/2017 → …
Project: Research project
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Department of Public Health, University of Helsinki
Wedenoja, J., Kaprio, J., Loukola, A., Korhonen, T., Hällfors, J., Heikkilä, K., Ripatti, S. & Tikkanen, E.
01/04/2011 → …
Project: Research project
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Persinalized disease risk assessment platform
Palta, P., Häppölä, P. & Koskela, J.
01/06/2018 → 31/12/2019
Project: Research project
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ePerMed: Rise of scientific excellence and collaboratio for implementing personalised medicine in Estonia
01/01/2016 → 31/12/2018
Project: Other project
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Targeting the Tie-2 Receptor With Faricimab in Central Serous Chorioretinopathy: A Case Series Motivated by a Genetic Finding
Rämö, J. T., Kim, L. A., Stryjewski, T., Shah, P. P., Bejjani, R., Brodie, F. L., Eliott, D., Sobrin, L., Vavvas, D. G. & Rossin, E. J., Jan 2025, In: American Journal of Ophthalmology. 269, p. 246-254 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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A genomic mutational constraint map using variation in 76,156 human genomes
Genome Aggregation Database Consortium, Chen, S., Francioli, L. C., Goodrich, J. K., Färkkilä, M., Groop, L., Holi, M. M., Kaprio, J., Koskinen, S., Palotie, A., Ripatti, S., Suvisaari, J., Tuomi, T., Vartiainen, E., Wessman, M., Daly, M. J. & Neale, B. M., 4 Jan 2024, In: Nature. 625, 7993, p. 92-100 27 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Association between butyrate-producing gut bacteria and the risk of infectious disease hospitalisation: results from two observational, population-based microbiome studies
Kullberg, R. F. J., Wikki, I., Haak, B. W., Kauko, A., Galenkamp, H., Peters-Sengers, H., Butler, J. M., Havulinna, A. S., Palmu, J., McDonald, D., Benchraka, C., Abdel-Aziz, M. I., Prins, M., Maitland van der Zee, A. H., van den Born, B. J., Jousilahti, P., de Vos, W. M., Salomaa, V., Knight, R., Lahti, L., & 3 others , 2024, In: The Lancet microbe. 5, 9, 10 p., 100864.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Associations between gut microbiota and incident fractures in the FINRISK cohort
Grahnemo, L., Kambur, O., Lahti, L., Jousilahti, P., Niiranen, T., Knight, R., Salomaa, V., Havulinna, A. S. & Ohlsson, C., 2024, In: npj Biofilms and Microbiomes. 10, 1, 10 p., 69.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Associations of "weekend Warrior" Physical Activity with Incident Disease and Cardiometabolic Health
Kany, S., Al-Alusi, M. A., Rämö, J. T., Pirruccello, J. P., Churchill, T. W., Lubitz, S. A., Maddah, M., Guseh, J. S., Ellinor, P. T. & Khurshid, S., 2024, In: Circulation . 150, 6, p. 1236-1247 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Activities
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Genetic influences in detailed lipid profiles and their role in cardiometabolic disease risk
Samuli Ripatti (Speaker)
11 May 2023Activity: Talk or presentation types › Invited talk
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Esimerkkejä suomalaisten geenitiedon avulla tehdyistä tutkimuslöydöksistä
Samuli Ripatti (Speaker)
25 Sept 2023Activity: Talk or presentation types › Oral presentation
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XXVI SIGU National Congress: Gene-microbiome interactions in human health and complex diseases
Samuli Ripatti (Invited speaker)
6 Oct 2023Activity: Talk or presentation types › Oral presentation
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Nature Genetics (Journal)
Samuli Ripatti (Reviewer)
19 Feb 2023Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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Nature Genetics (Journal)
Samuli Ripatti (Reviewer)
27 Nov 2023Activity: Publication peer-review and editorial work types › Peer review of manuscripts
Prizes
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ASHG 2020 Virtual Meeting, Reviewers’ Choice Abstract Award
Kiiskinen, Tuomo (Recipient), 31 Aug 2020
Prize: Prizes and awards
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The Best FinnGen Paper of the Year Award
Kiiskinen, Tuomo (Recipient), 26 Sept 2023
Prize: Prizes and awards
Press/Media
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Artikkeli Hoiva ja Terveys-sivustolla: Samuli Ripatti Suomen molekyylilääketieteen instituutin johtoon
05/05/2023
1 item of Media coverage
Press/Media: Press / Media
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Haastattelu Mediuutisissa: FIMM:lle uusi johtaja – genetiikan ja biometrian konkari on töpinöissä
03/05/2023
1 Media contribution
Press/Media: Press / Media
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Artikkeli Nordic EMBL Partnership for Molecular Medicine-sivustolla: Professor Samuli Ripatti to lead FIMM
03/05/2023
1 item of Media coverage
Press/Media: Press / Media
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Haastattelu Tiedeykkösessä: Vaihdetaanko labrojen poistogeeniset hiiret suomalaisiin, joilla on vastaavat sammuneet geenit?
14/09/2021
1 Media contribution
Press/Media: Press / Media