• P.O. Box 20 (Tukholmankatu 8), Biomedicum 2U

    00014 University of Helsinki

    Finland

Organization profile

Organisation Profile

The Ripatti group studies genome-wide variation and its relation to complex traits and diseases, with a particular focus, but not limited to, on cardiovascular diseases and metabolism. We build on our understanding of genome-wide variation, Finnish genetically and epidemiologically well-profiled cohorts and knowledge and development of statistical and computational tools, and aim at identifying variants, genes and genetic loci modifying complex disease risks. We also study ways to translate the findings into potential intervention targets and comprehensive disease risk assessments.

International and National Collaboration Publications and projects within past five years.

Projects 2010 2019

Publications 2010 2020

Genomic prediction of alcohol-related morbidity and mortality

Kiiskinen, T., Mars, N., Palviainen, T., Koskela, J., Rämö, J., Ripatti, P., Ruotsalainen, S., Project, F., GSCAN Consortium, Palotie, A., Madden, P. A. F., Rose, R. J., Kaprio, J., Salomaa, V., Mäkelä, P., Havulinna, A. & Ripatti, S., 21 Jan 2020, In : Translational Psychiatry.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study

Lindbohm, J., Sipilä, P. N., Mars, N. J., Pentti, J., Ahmadi-Abhari, S., Brunner, E. J., Shipley, M. J., Singh-Manoux, A., Tabak, A. G. & Kivimäki, M., Apr 2019, In : The Lancet Public Health. 4, 4, p. E189-E199 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

PRACTICAl Consortium, Law, P. J., Timofeeva, M., Fernandez-Rozadilla, C., Palin, K., Hänninen, U. A., Cajuso, T., Tanskanen, T., Kondelin, J., Kaasinen, E., Sarin, A-P., Eriksson, J. G., Jousilahti, P., Ripatti, S., Palotie, A., Renkonen-Sinisalo, L., Lepistö, A., Aaltonen, L. A., Rissanen, H., Salomaa, V. & 3 others, Böhm, J., Mecklin, J-P. & Pukkala, E., 14 May 2019, In : Nature Communications. 10, 15 p., 2154.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease

IBD Pharmacogenetics Study Grp, Walker, G. J., Harrison, J. W., Daly, M. J. & Koskela, J., 26 Feb 2019, In : JAMA : The Journal of the American Medical Association. 321, 8, p. 773-785 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts

Ahola-Olli, A. V., Mustelin, L., Kalimeri, M., Kettunen, J., Jokelainen, J., Auvinen, J., Puukka, K., Havulinna, A. S., Lehtimäki, T., Kähönen, M., Juonala, M., Keinänen-Kiukaanniemi, S., Salomaa, V., Perola, M., Järvelin, M-R., Ala-Korpela, M., Raitakari, O. & Wurtz, P., Dec 2019, In : Diabetologia. 62, 12, p. 2298-2309 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Activities 2007 2019

Novo Nordisk Foundation Center for Basic Metabolic Research Platform (Event)

Samuli Ripatti (Board member)
27 May 201928 May 2019

Activity: Membership typesMembership or other role in national/international committee, council, board

New England Journal of Medicine (Journal)

Samuli Ripatti (Reviewer)
22 Jan 2019

Activity: Publication peer-review and editorial work typesPeer review of manuscripts

Cell (Journal)

Samuli Ripatti (Reviewer)
1 Feb 2019

Activity: Publication peer-review and editorial work typesPeer review of manuscripts

Lecture: We have the polygenic risks - but do they matter in prevention?

Samuli Ripatti (Speaker)
7 Feb 20198 Feb 2019

Activity: Talk or presentation typesOral presentation

Primary GWAS plan & schedule

Samuli Ripatti (Speaker)
12 Apr 2019

Activity: Talk or presentation typesOral presentation