Department of Anatomy

  • Finland

Publications

2020
Open Access

Anatomical variations and pathological changes in the hearts of free-ranging Eurasian lynx (Lynx lynx) in Finland

Kareinen, I., Lavonen, E., Viranta-Kovanen, S., Holmala, K. & Laakkonen, J., 18 Jan 2020, In : European Journal of Wildlife Research. 66, 1, 11 p., 21.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins

Ruhanen, H., Haridas, P. A. N., Minicocci, I., Taskinen, J. H., Palmas, F., di Costanzo, A., D'Erasmo, L., Metso, J., Partanen, J., Dalli, J., Zhou, Y., Arca, M., Jauhiainen, M., Käkelä, R. & Olkkonen, V. M., Jul 2020, In : Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1865, 7, 11 p., 158679.

Research output: Contribution to journalArticleScientificpeer-review

An International Partnership of 12 Anatomy Departments - Improving Global Health through Internationalization of Medical Education

Wu, A., Noel, G. P. J. C., Wingate, R., Kielstein, H., Sakurai, T., Viranta-Kovanen, S., Chien, C-L., Traxler, H., Waschke, J., Vielmuth, F., Sagoo, M. G., Kitahara, S., Kato, Y., Keay, K. A., Olsen, J. & Bernd, P., 2020, In : Annals of Global Health. 86, 1, 14 p., 27.

Research output: Contribution to journalArticleScientificpeer-review

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Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells

Meneses-Salas, E., García-Melero, A., Kanerva, K., Blanco-Muñoz, P., Morales-Paytuvi, F., Bonjoch, J., Heeren, J., Lu, A., Pol, A., Tebar, F., Ikonen, E., Grewal, T., Enrich, C. & Rentero, C., Jul 2020, In : Cellular and Molecular Life Sciences. 77, 14, p. 2839-2857 19 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Bacterial Phytochrome as a Scaffold for Engineering of Receptor Tyrosine Kinases Controlled with Near-Infrared Light

Leopold, A., Pletnev, S. & Verkhusha, V. V., 12 Jun 2020, In : Journal of Molecular Biology. 432, 13, p. 3749-3760 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes

Latorre, J., Ortega, F. J., Liñares-Pose, L., Moreno-Navarrete, J. M., Lluch, A., Comas, F., Oliveras-Cañellas, N., Ricart, W., Höring, M., Zhou, Y., Liebisch, G., Nidhina Haridas, P. A., Olkkonen, V. M., López, M. & Fernández-Real, J. M., Mar 2020, In : EBioMedicine. 53, 16 p., 102697.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Open Access
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Expression of LHCG receptors in the human penis

Zirnask, H., Pöllänen, P., Suutre, S., Kuuslahti, M., Kotsar, A., Pakarainen, T. & Kokk, K., 2 Jan 2020, In : Aging Male. 23, 1, p. 8-13 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Finnish neuroscience from past to present

Korpi, E. R., Lindholm, D., Panula, P., Tienari, P. J. & Haltia, M., 3 Feb 2020, In : European Journal of Neuroscience. 17 p.

Research output: Contribution to journalEditorialScientific

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Genetic lack of histamine upregulates dopamine neurotransmission and alters rotational behavior but not levodopa-induced dyskinesia in a mouse model of Parkinson’s disease

Koski, S. K., Leino, S., Panula, P., Rannanpää, S. & Salminen, O., 11 Jun 2020, In : Neuroscience Letters. 729, 6 p., 134932.

Research output: Contribution to journalArticleScientificpeer-review

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High-content imaging and structure-based predictions reveal functional differences between Niemann-Pick C1 variants

Vanharanta, L., Peränen, J., Pfisterer, S. G., Enkavi, G., Vattulainen, I. & Ikonen, E., May 2020, In : Traffic. 21, 5, p. 386-397 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Histamine, histamine H3 receptor, and alcohol use disorder

Panula, P., 22 Feb 2020, In : British Journal of Pharmacology. 177, 3, p. 634-641 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

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Hypertriglyceridemia-induced acute pancreatitis: A prospective, multicenter, international cohort analysis of 716 acute pancreatitis cases

Mosztbacher, D., Hanák, L., Farkas, N., Szentesi, A., Mikó, A., Bajor, J., Sarlós, P., Czimmer, J., Vincze, Á., Hegyi, P. J., Erőss, B., Takács, T., Czakó, L., Németh, B. C., Izbéki, F., Halász, A., Gajdán, L., Hamvas, J., Papp, M., Földi, I. & 25 others, Fehér, K. E., Varga, M., Csefkó, K., Török, I., Farkas, H. P., Mickevicius, A., Maldonado, E. R., Sallinen, V., Novák, J., Ince, A. T., Galeev, S., Bod, B., Sümegi, J., Pencik, P., Dubravcsik, Z., Illés, D., Gódi, S., Kui, B., Márta, K., Pécsi, D., Varjú, P., Szakács, Z., Darvasi, E., Párniczky, A. & Hegyi, P., Jun 2020, In : Pancreatology. 20, 4, p. 608-616 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Increased Sensitivity of Mice Lacking Extrasynaptic delta-Containing GABA(A) Receptors to Histamine Receptor 3 Antagonists

Abdurakhmanova, S., Grotell, M., Kauhanen, J., Linden, A-M., Korpi, E. R. & Panula, P., 6 May 2020, In : Frontiers in Pharmacology. 11, 13 p., 594.

Research output: Contribution to journalArticleScientificpeer-review

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Is preoperative bowel preparation always superfluous? reply

Koskenvuo, L. & Sallinen, V., 7 Mar 2020, In : Lancet. 395, 10226, p. 782-782 1 p.

Research output: Contribution to journalLetterScientific

Open Access

Kirurgia vaatii erityisjärjestelyjä COVID-19-pandemian aikana : välttämätön kirurginen toiminta on turvattava

Leppäniemi, A., Tolonen, M., Mentula, P. & Sallinen, V., 2020, In : Duodecim. 136, 12, p. 1377-1379 3 p.

Research output: Contribution to journalEditorialProfessional

Kuinka solut varastoivat rasvaa?

Salo, V. & Ikonen, E., 2020, In : Duodecim. 136, 5, p. 487-495 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Minne katosivat hyljekoirat

Mannermaa, K. & Viranta-Kovanen, S., 2020, Karjalainen eräperinne. Kirkinen, T. (ed.). Helsinki: Maahenki, p. 97 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientific

Mitä uutta elinsiirtorintamalla?

Lempinen, M., Ahopelto, K. & Sallinen, V., 2020, In : Finnanest.. 53, 2, p. 140-145 6 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Optogenetic regulation of endogenous proteins

Redchuk, T. A., Karasev, M. M., Verkhusha, P. V., Donnelly, S. K., Hülsemann, M., Virtanen, J., Moore, H. M., Vartiainen, M. K., Hodgson, L. & Verkhusha, V. V., 2020, In : Nature Communications. 11, 12 p., 605.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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OSBP-Related Protein 5L Maintains Intracellular IP3/Ca2+ Signaling and Proliferation in T Cells by Facilitating PIP2 Hydrolysis

Xu, M., Zhu, B., Cao, X., Li, S., Li, D., Zhou, H., Olkkonen, V. M., Zhong, W., Xu, J. & Yan, D., 1 Mar 2020, In : Journal of Immunology. 204, 5, p. 1134-1145 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Outcomes and quality of life after major bile duct injury in long-term follow-up

Koppatz, H., Sallinen, V., Mäkisalo, H. & Nordin, A., 22 Jun 2020, In : Surgical Endoscopy. 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Surface stabilization and dissolution rate improvement of amorphous compacts with thin polymer coatings: can we have it all?

Novakovic, D., Peltonen, L., Isomäki, A. O., Fraser-Miller, S. J., Hagner Nielsen, L., Laaksonen, T. & Strachan, C., 6 Apr 2020, In : Molecular Pharmaceutics. 17, 4, p. 1248-1260 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1 alpha PARylation in db/db mice

Wang, H., Kuusela, S., Rinnankoski-Tuikka, R., Dumont, V., Bouslama, R., Ramadan, U. A., Waaler, J., Linden, A-M., Chi, N-W., Krauss, S., Pirinen, E. & Lehtonen, S., 21 Apr 2020, In : International Journal of Obesity. 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Taurine Promotes Axonal Regeneration after a Complete Spinal Cord Injury in Lampreys

Sobrido-Camean, D., Fernandez-Lopez, B., Pereiro, N., Lafuente, A., Celina Rodicio, M. & Barreiro-Iglesias, A., 15 Mar 2020, In : Journal of Neurotrauma. 37, p. 899–903 5 p.

Research output: Contribution to journalArticleScientificpeer-review

The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser

Claesson, E., Wahlgren, W. Y., Takala, H., Pandey, S., Castillon, L., Kuznetsova, V., Henry, L., Panman, M., Carrillo, M., Kubel, J., Nanekar, R., Isaksson, L., Nimmrich, A., Cellini, A., Morozov, D., Maj, M., Kurttila, M., Bosman, R., Nango, E., Tanaka, R. & 10 others, Tanaka, T., Fangjia, L., Iwata, S., Owada, S., Moffat, K., Groenhof, G., Stojkovic, E. A., Ihalainen, J. A., Schmidt, M. & Westenhoff, S., 31 Mar 2020, In : eLife. 9, 18 p., 53514.

Research output: Contribution to journalArticleScientificpeer-review

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2019

Abnormal behavior, striatal dopamine turnover and opioid peptide gene expression in histamine-deficient mice

Abdurakhmanova, S., Semenova, S., Piepponen, T. P. & Panula, P., Nov 2019, In : Genes, Brain and Behavior. 18, 8, 12 p., 12595.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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A comparative map of macroautophagy and mitophagy in the vertebrate eye

McWilliams, T. G., Prescott, A. R., Villarejo-Zori, B., Ball, G., Boya, P. & Ganleya, I. G., 3 Jul 2019, In : Autophagy. 15, 7, p. 1296-1308 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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An efficient auxin-inducible degron system with low basal degradation in human cells

Li, S., Prasanna, X., Salo, V. T., Vattulainen, I. & Ikonen, E., Sep 2019, In : Nature methods. 16, 9, p. 866-+ 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Cell-Nanoparticle Interactions at (Sub)-Nanometer Resolution Analyzed by Electron Microscopy and Correlative Coherent Anti-Stokes Raman Scattering

Saarinen, J. K. S., Gütter, F., Lindman, M. M., Agopov, M., Fraser-Miller, S. J., Scherließ, R., Jokitalo, E., Almeida Santos, H., Peltonen, L., Isomäki, A. & Strachan, C. J., Apr 2019, In : Biotechnology Journal. 14, 4, 10 p., 1800413.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Open Access
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Determinants of treatment and outcomes of diverticular abscesses

Mali, J., Mentula, P., Leppäniemi, A. & Sallinen, V., 8 Jul 2019, In : World journal of emergency surgery. 14, 1, 9 p., 31.

Research output: Contribution to journalArticleScientificpeer-review

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Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes

Garcia-Garcia, A., Korn, C., Garcia-Fernandez, M., Domingues, O., Villadiego, J., Martin-Perez, D., Isern, J., Bejarano-Garcia, J. A., Zimmer, J., Perez-Simon, J. A., Toledo-Aral, J. J., Michel, T., Airaksinen, M. S. & Mendez-Ferrer, S., 17 Jan 2019, In : Blood. 133, 3, p. 224-236 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of Pretransplant Dialysis Modality on Outcomes After Simultaneous Pancreas-Kidney Transplantation

Räihä, J., Helanterä, I., Ekstrand, A., Nordin, A., Sallinen, V. & Lempinen, M., 19 Jul 2019, In : Annals of transplantation. 24, p. 426-431 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Fluorescent Biosensors for Neurotransmission and Neuromodulation: Engineering and Applications

Leopold, A. V., Shcherbakova, D. & Verkhusha, V. V., 23 Oct 2019, In : Frontiers in Cellular Neuroscience. 13, 18 p., 474.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Gastroenterologinen kirurgia - kandin tietolaatikko

Sallinen, V. & Salminen, P., 2019, In : Duodecim. 135, 16, p. 1546 1 p.

Research output: Contribution to journalArticleProfessional

HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo

Gungor, B., Vanharanta, L., Hölttä-Vuori, M., Pirhonen, J., Petersen, N. H. T., Gramolelli, S., Ojala, P. M., Kirkegaard, T. & Ikonen, E., Oct 2019, In : Molecular metabolism. 28, p. 135-143 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids

Luukkonen, P. K., Nick, A., Hölttä-Vuori, M., Thiele, C., Isokuortti, E., Lallukka-Brück, S., Zhou, Y., Hakkarainen, A., Lundbom, N., Peltonen, M., Orho-Melander, M., Oresic, M., Hyötyläinen, T., Hodson, L., Ikonen, E. & Yki-Järvinen, H., 22 Aug 2019, In : JCI INSIGHT. 4, 16, 13 p., 127902.

Research output: Contribution to journalArticleScientificpeer-review

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Internationalization of of Medical Education - Building a Program to Prepare Future Leaders in Healthcare

Wu, A., Kielstein, H., Sakurai, T., Noel, G., Viranta-Kovanen, S. K., Chien, C-L. & Bernd, P., 13 Feb 2019, In : Medical science educator. 29, 2, p. 535–547 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

In vivo photoacoustic multi-contrast imaging and detection of protein interactions using a small near-infrared photochromic protein

Li, L., Shemetov, A. A., Hu, P., Shcherbakova, D. M., Shi, J., Yao, J., Verkhusha, V. V. & Wang, L. V., 2019, PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2019. Oraevsky, A. A. & Wang, L. V. (eds.). Bellingham, WA: SPIE - the international society for optics and photonics, 6 p. (Proceedings of SPIE; vol. 10878).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion

Dufurrena, Q., Bäck, N., Mains, R., Hodgson, L., Tanowitz, H., Mandela, P., Eipper, B. & Kuliawat, R., Jan 2019, In : Journal of Molecular Endocrinology. 62, 1, p. 47-65 19 p.

Research output: Contribution to journalArticleScientificpeer-review

Laparoskooppinen kolekystektomia

Sallinen, V., Mentula, P. & Scheinin, T., 2019, In : Duodecim. 135, 6, p. 565-573 9 p.

Research output: Contribution to journalArticleProfessional

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Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export

Heybrock, S., Kanerva, K., Meng, Y., Ing, C., Liang, A., Xiong, Z-J., Weng, X., Kim, Y. A., Collins, R., Trimble, W., Pomes, R., Prive, G. G., Annaert, W., Schwake, M., Heeren, J., Lullmann-Rauch, R., Grinstein, S., Ikonen, E., Saftig, P. & Neculai, D., 6 Aug 2019, In : Nature Communications. 10, 12 p., 3521.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Machine learning of human plasma lipidomes for obesity estimation in a large population cohort

Gerl, M. J., Klose, C., Surma, M. A., Fernandez, C., Melander, O., Männistö, S., Borodulin, K., Havulinna, A. S., Salomaa, V., Ikonen, E., Cannistraci, C. V. & Simons, K., 18 Oct 2019, In : PLoS Biology. 17, 10, 25 p., e3000443.

Research output: Contribution to journalArticleScientificpeer-review

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Maksaportin sappitiesyöpä eli Klatskinin tuumori

Sallinen, V., Peltola, K. & Mäkisalo, H., 2019, In : Duodecim. 135, 6, p. 599-607 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

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Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice

Galli, E., Rossi, J., Neumann, T., Andressoo, J-O., Drinda, S. & Lindholm, P., 4 Oct 2019, In : Scientific Reports. 9, 12 p., 14318.

Research output: Contribution to journalArticleScientificpeer-review

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Metabolomic Signature of Angiopoietin-Like Protein 3 Deficiency in Fasting and Postprandial State

Tikkanen, E., Minicocci, I., Hällfors, J., Di Costanzo, A., D'Erasmo, L., Poggiogalle, E., Donini, L. M., Wurtz, P., Jauhiainen, M., Olkkonen, V. M. & Arca, M., Apr 2019, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 39, 4, p. 665-674 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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