Department of Biochemistry and Developmental Biology

  • Finland

Publications 1980 2019

Filter
Article

15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer

Thiel, A., Ganesan, A., Mrena, J., Junnila, S., Nykänen, A., Hemmes, A., Tai, H-H., Monni, O., Kokkola, A. J., Haglund, C., Petrova, T. & Ristimäki, A., 2009, In : Clinical Cancer Research. 15, 14, p. 4572-4580 9 p.

Research output: Contribution to journalArticleScientificpeer-review

19-Nortestosterone influences neural stem cell proliferation and neurogenesis in the rat brain

Brannvall, K., Bogdanovic, N., Korhonen, L. & Lindholm, D., 2005, In : European Journal of Neuroscience. 21, p. 871-878 8 p.

Research output: Contribution to journalArticleScientificpeer-review

3D view to tumor suppression Lkb1, polarity and the arrest of oncogenic c-Myc

Partanen, J. I., Nieminen, A. I. & Klefström, J., 2009, In : Cell Cycle. 8, p. 716-724 9 p.

Research output: Contribution to journalArticleScientificpeer-review

A2B5+/GFAP+ Cells of Rat Spinal Cord Share a Similar Lipid Profile with Progenitor Cells: A Comparative Lipidomic Study

Itokazu, Y., Tajima, N., Kerosuo, L., Somerharju, P., Sariola, H., Yu, R. K. & Kakela, R., Jul 2016, In : Neurochemical Research. 41, 7, p. 1527-1544 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

ABC lipid transporters: extruders, flippases, or flopless activators?

Meer, G. V., Halter, D., Sprong, H., Somerharju, P. & Egmond, M., 2006, In : FEBS Letters. 580, p. 1171-1177 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Accumulation of bis(monoacylglycero)phosphate and gangliosides in mouse models of neuronal ceroid lipofuscinosis

Jabs, S., Quitsch, A., Käkelä, R., Koch, B., Tyynelä, J., Brade, H., Glatzel, M., Walkley, S., Saftig, P., Vanier, M. & Braulke, T., 2008, In : Journal of Neurochemistry. 106, p. 1415-1425 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Accurate genetic diagnosis of Finnish pulmonary arterial hypertension patients using oligonucleotide-selective sequencing

Vattulainen, S., Aho, J., Salmenperä, P., Bruce, S., Tallila, J., Gentile, M., Sankelo, M., Laitinen, T., Koskenvuo, J. W., Alastalo, T-P. & Myllykangas, S., 2015, In : Molecular Genetics & Genomic Medicine. 3, 4, p. 354-362 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

A comment on Schmidt’s experiments: [Letter]

Hemilä, H., 1982, In : Skeptical inquirer. 6, 4, p. 78-78 1 p.

Research output: Contribution to journalArticleScientific

Open Access
File

Activated mast cells increase the level of endothelin-1 mRNA in cocultured endothelial cells and degrade the secreted peptide

Metsarinne, K. P., Vehmaan-Kreula, P., Kovanen, P. T., Saijonmaa, O., Baumann, M., Wang, Y. F., Nyman, T., Fyhrquist, F. Y. & Eklund, K. K., 2002, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 22, p. 268-273 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Activated polymorphonuclear leucocytes consume vitamin C

Hemilä, H., Roberts, P. & Wikström, M., 1984, In : FEBS Letters. 178, 1, p. 25-30 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Activation of calpain-1 in human carotid artery atherosclerotic lesions

Goncalves, I., Nitulescu, M., Saido, T., Dias, N., Pedro, L., Fernandes e Fernandes, J., Ares, M. & Pörn-Ares, I., 2009, In : BMC Cardiovascular Disorders. 9 (2009), p. 26 1 p.

Research output: Contribution to journalArticleScientificpeer-review

Activation of phospholipase A2 by Hsp70 in vitro

Mahalka, A. K., Code, C., Jahromi, B. R., Kirkegaard, T., Jaattela, M. & Kinnunen, P. K. J., Oct 2011, In : Biochimica et Biophysica Acta. Biomembranes. 1808, 10, p. 2569-2572 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Activator protein-1 in human male germ cell apoptosis

Suomalainen, L., Dunkel, L., Ketola, I., Eriksson, M., Erkkilä, K., Oksjoki, R., Taari, K., Heikinheimo, M. & Pentikäinen, V., 2004, In : Molecular Human Reproduction. 10, 10, p. 743–753 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Active transcriptomic and proteomic reprogramming in the C-elegans nucleotide excision repair mutant xpa-1

Arczewska, K. D., Tomazella, G. G., Lindvall, J. M., Kassahun, H., Maglioni, S., Torgovnick, A., Henriksson, J., Matilainen, O., Marquis, B. J., Nelson, B. C., Jaruga, P., Babaie, E., Holmberg, C., Burglin, T. R., Ventura, N., Thiede, B. & Nilsen, H., May 2013, In : Nucleic Acids Research. 41, 10, p. 5368-5381 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

ACTIVITY-DEPENDENT AND HORMONAL-REGULATION OF NEUROTROPHIN MESSENGER-RNA LEVELS IN THE BRAIN - IMPLICATIONS FOR NEURONAL PLASTICITY

LINDHOLM, D., CASTREN, E., BERZAGHI, M., BLOCHL, A. & THOENEN, H., Nov 1994, In : Journal of Neurobiology. 25, 11, p. 1362-1372 11 p.

Research output: Contribution to journalArticleScientificpeer-review

ACTIVITY-DEPENDENT REGULATION OF SYNTHESIS AND RELEASE OF NEUROTROPHINS - IMPLICATIONS FOR NEURONAL PLASTICITY

THOENEN, H., BLOCHI, A., BERZAGHI, M., BERNINGER, M., CASTREN, E. & LINDHOLM, D., 1995, In : Journal of Neurochemistry. 65, p. S133-S133 1 p.

Research output: Contribution to journalArticleScientificpeer-review

Activity of BKCa channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells

Tajima, N., Itokazu, Y., Korpi, E. R., Somerharju, P. & Käkelä, R., 2011, In : Journal of Biological Chemistry. 286, 7, p. 5624-5638 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production

Riederer, M., Ojala, P. J., Hrzenjak, A., Tritscher, M., Hermansson, M., Watzer, B., Schweer, H., Desoye, G., Heinemann, A. & Frank, S., 2010, In : Journal of Lipid Research. 51, p. 2957-2966 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Acyl Chain-Dependent Effect of Lysophosphatidylcholine on Endothelium-Dependent Vasorelaxation

Rao, S. P., Riederer, M., Lechleitner, M., Hermansson, M., Desoye, G., Hallstroem, S., Graier, W. F. & Frank, S., 31 May 2013, In : PLoS One. 8, 5, p. Article Number: e65155 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Acyl chain-dependent effect of lysophosphatidylcholine on human neutrophils

Ojala, P. J., Hirvonen, T. E., Hermansson, M., Somerharju, P. & Parkkinen, J., 2007, In : Journal of Leukocyte Biology. 82, p. 1501-1509 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Acyl-Chain Mismatch Driven Superlattice Arrangements in DPPC/DLPC/Cholesterol Bilayers

Cannon, B., Lewis, A., Somerharju, P., Virtanen, J., Huang, J. & Cheng, K. H., 2010, In : Journal of Physical Chemistry B. 114, p. 10105-10113 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Adipocyte morphology and implications for metabolic derangements in acquired obesity

Heinonen, S., Saarinen, L., Naukkarinen, J., Rodriguez, A., Fruhbeck, G., Hakkarainen, A., Lundbom, J., Lundbom, N., Vuolteenaho, K., Moilanen, E., Arner, P., Hautaniemi, S., Suomalainen, A., Kaprio, J., Rissanen, A. & Pietilainen, K. H., Nov 2014, In : International Journal of Obesity. 38, 11, p. 1423-1431 9 p.

Research output: Contribution to journalArticleScientificpeer-review

A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients

Tumiati, M., Hietanen, S., Hynninen, J., Pietilä, E., Färkkilä, A., Kaipio, K., Roering, P., Huhtinen, K., Alkodsi, A., Li, Y., Lehtonen, R., Erkan, E. P., Tuominen, M. M., Lehti, K., Hautaniemi, S. K., Vähärautio, A., Grenman, S., Carpen, O. & Kauppi, L., 15 Sep 2018, In : Clinical Cancer Research. 24, 18, p. 4482-4493 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Aikuisen luuytimen kantasoluilla ei roolia verisuonten endoteelin uudismuodostuksessa ja kiinteiden kasvaimien kehittymisessä: [referaatti Proc Natl Acad Sci -lehden artikkelista]

Lauttia, S., Palm, J., Rossi, D., Kaskenpää, N., Rajantie, I., Ylä-Herttuala, S., Alitalo, K., Weissman, I. & Salven, P., 2008, In : Duodecim. 124, p. 1083 1 p.

Research output: Contribution to journalArticleScientific

A knot in the protein structure - probing the near-infrared fluorescent protein iRFP designed from a bacterial phytochrome

Stepanenko, O. V., Bublikov, G. S., Stepanenko, O. V., Shcherbakova, D. M., Verkhusha, V. V., Turoverov, K. K. & Kuznetsova, I. M., May 2014, In : The FEBS Journal. 281, 9, p. 2284-2298 15 p.

Research output: Contribution to journalArticleScientificpeer-review

A large set of estrogen receptor beta-interacting proteins identified by tandem affinity purification in hormone-responsive human breast cancer cell nuclei

Nassa, G., Tarallo, R., Ambrosino, C., Bamundo, A., Ferraro, L., Paris, O., Ravo, M., Guzzi, P. H., Cannataro, M., Baumann, M., Nyman, T. A., Nola, E. & Weisz, A., 2011, In : Proteomics (Weinheim). 11, p. 159-165 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Alpha2B-adrenoceptors couple to Ca2+ increase in both endogenous and recombinant expression systems

Holmberg-Still, C., Kukkonen, J. P., Bischoff, A., Nasman, J., Courtney, M. J., Michel, M. C. & Åkerman, K., 1998, In : European Journal of Pharmacology. 363, 1, p. 65-74

Research output: Contribution to journalArticleScientificpeer-review

Altered distribution and levels of cathepsind and cystatins in amyotrophic lateral sclerosis transgenic mice: Possible roles in motor neuron survival

Wootz, H., Weber, E., Korhonen, L. & Lindholm, D., 2006, In : Neuroscience. 143, 2, p. 419-430 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Altered hepatic lipid status and apolipoprotein A-I metabolism in mice lacking phospholipid transfer protein

Siggins, S., Bykov, I., Hermansson, M., Somerharju, P., Lindros, K., Miettinen, T., Jauhiainen, M., Olkkonen, V., Ehnholm, C. & Miettinen, T. A., 2007, In : Atherosclerosis. 190, p. 114-123 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Alternative splicing discriminates molecular subtypes and has prognostic impact in diffuse large B-cell lymphoma

Leivonen, S-K., Taskinen, M., Cervera, A., Karjalainen-Lindsberg, M-L., Delabie, J., Holte, H., Lehtonen, R., Hautaniemi, S. & Leppa, S., 25 Aug 2017, In : Blood cancer journal. 7, 10 p., 596.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

AMPHOTERIN, THE 30-KDA PROTEIN IN A FAMILY OF HMG1-TYPE POLYPEPTIDES - ENHANCED EXPRESSION IN TRANSFORMED-CELLS, LEADING-EDGE LOCALIZATION, AND INTERACTIONS WITH PLASMINOGEN ACTIVATION

PARKKINEN, J., RAULO, E., MERENMIES, J., NOLO, R., KAJANDER, E. O., BAUMANN, M. & RAUVALA, H., 1993, In : Journal of Biological Chemistry. 268, p. 19726-19738 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Amphoterin includes a sequence motif which is homologous to the Alzheimer's beta-amyloid peptide (A beta), forms amyloid fibrils in vitro, and binds avidly to A beta

Kallijarvi, J., Haltia, M. & Baumann, M. H., 2001, In : Comprehensive Biochemistry. 40, p. 10032-10037 6 p.

Research output: Contribution to journalArticleScientificpeer-review

A mutation in hairless dogs implicates FOXI3 in ectodermal development

Drögemuller, C., Karlsson, E. K., Hytönen, M. K., Perloski, M., Dolf, G., Sainio, K., Lohi, H., Lindblad-Toh, K. & Leeb, T., 2008, In : Science. 321, 5895, p. 1462 1 p.

Research output: Contribution to journalArticleScientificpeer-review

A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration

Tyynela, J., Sohar, I., Sleat, D. E., Gin, R. M., Donnelly, R. J., Baumann, M., Haltia, M. & Lobel, P., 2000, In : EMBO Journal. 19, p. 2786-2792 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Amyloid-type fiber formation in control of enzyme action: interfacial activation of phospholipase A2

Code, C., Domanov, Y., Jutila, A. & Kinnunen, P., 2008, In : Biophysical Journal. 95, p. 215-224 10 p.

Research output: Contribution to journalArticleScientificpeer-review

AN ACTIVE SINGLE-CHAIN ANTIBODY CONTAINING A CELLULASE LINKER DOMAIN IS SECRETED BY ESCHERICHIA-COLI

TAKKINEN, K., LAUKKANEN, M. L., SIZMANN, D., ALFTHAN, K., IMMONEN, T., VANNE, L., KAARTINEN, M., KNOWLES, J. K. C. & TEERI, T. T., 1991, In : Protein Engineering. 4, p. 837-841 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Anagrelide for Gastrointestinal Stromal Tumor

Pulkka, O-P., Gebreyohannes, Y. K., Wozniak, A., Mpindi, J-P., Tynninen, O., Icay, K., Cervera, A., Keskitalo, S., Murumägi, A., Kulesskiy, E., Laaksonen, M., Wennerberg, K., Varjosalo, M., Laakkonen, P., Lehtonen, R., Hautaniemi, S., Kallioniemi, O., Schöffski, P., Sihto, H. & Joensuu, H., 1 Mar 2019, In : Clinical Cancer Research. 25, 5, p. 1676-1687 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Analysis of BMP4 and BMP7 signaling in breast cancer cells unveils time-dependent transcription patterns and highlights a common synexpression group of genes

Rodriguez-Martinez, A., Alarmo, E-L., Saarinen, L., Ketolainen, J., Nousiainen, K., Hautaniemi, S. & Kallioniemi, A., 2011, In : BMC Medical Genomics. 4, p. 80 16 p.

Research output: Contribution to journalArticleScientificpeer-review

An artifactual in situ hybridization signal associated with apoptosis in rat embryo

Raatikainen-Ahokas, A., Immonen, T., Rossi, P. O., Sainio, K. & Sariola, H., 2000, In : Journal of Histochemistry and Cytochemistry. 48, 7, p. 955-961 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Ancestral T-box mutation is present in many, but not all, short-tailed dog breeds

Hytönen, M. K., Grall, A., Hedan, B., Dreano, S., Seguin, S. J., Delattre, D., Thomas, A., Galibert, F., Paulin, L., Lohi, H., Sainio, K. & Andre, C., 2009, In : Journal of Heredity. 100, 2, p. 236-240 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Aneuploidy-Associated Gene Expression Signatures Characterize Malignant Transformation in Ulcerative Colitis

Gerling, M., Nousiainen, K., Hautaniemi, S., Krueger, S., Fritzsche, B., Homann, N., Bruch, H-P., Auer, G., Roblick, U. J., Ried, T. & Habermann, J. K., 2013, In : Inflammatory Bowel Diseases. 19, 4, p. 691-703 13 p.

Research output: Contribution to journalArticleScientificpeer-review

A new parvovirus B19 genotype persistent in skin

Hokynar, K. C., Söderlund-Venermo, M., Pesonen, M., Ranki, A., Kiviluoto, O., Partio, E. K. & Hedman, K., 2002, In : Virology Journal. 25, 302, p. 224-228

Research output: Contribution to journalArticleScientificpeer-review

A new redox-dependent mechanism of MMP-1 activity control comprising reduced low-molecular-weight thiols and oxidizing radicals

Koch, S., Volkmar, C. M., Kolb-Bachofen, V., Korth, H-G., Kirsch, M., Horn, A. H. C., Sticht, H., Pallua, N. & Suschek, C. V., Mar 2009, In : Journal of Molecular Medicine. 87, 3, p. 261-272 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Anima: modular workflow system for comprehensive image data analysis

Rantanen, V., Valori, M. & Hautaniemi, S., 30 Jul 2014, In : Frontiers in Bioengineering and Biotechnology. 2, p. 25 25.

Research output: Contribution to journalArticleScientificpeer-review

ANION TRANSPORTERS SLC26A6 AND SLC26A7 HAVE SPECIFIC EXPRESSION IN JUXTAGLOMERULAR APPARATUS OF HUMAN KIDNEY

Kujala, M., Tienari, J., Lohi, H., Sariola, H., Lehtonen, E. & Kere, J., Jun 2005, In : Nephrology. 10, p. A240-A241 2 p.

Research output: Contribution to journalArticleScientificpeer-review

A Novel GUSB Mutation in Brazilian Terriers with Severe Skeletal Abnormalities Defines the Disease as Mucopolysaccharidosis VII

Hytönen, M. K., Arumilli, M., Lappalainen, A. K., Kallio, H., Snellman, M., Sainio, K. & Lohi, H., 2012, In : PLoS One. 7, 7, p. e40281 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines: Implications for Pandemrix-Associated Narcolepsy Risk

Vaarala, O., Vuorela, A., Partinen, M., Baumann, M., Freitag, T. L., Meri, S., Saavalainen, P., Jauhiainen, M., Soliymani, R., Kirjavainen, T., Olsen, P., Saarenpaa-Heikkila, O., Rouvinen, J., Roivainen, M., Nohynek, H., Jokinen, J., Julkunen, I. & Kilpi, T., 15 Dec 2014, In : PLoS One. 9, 12, 23 p., 114361.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Antimicrobial peptides temporins B and L induce formation of tubular lipid protrusions from supported phospholipid bilayers

Domanov, Y. & Kinnunen, P., 2006, In : Biophysical Journal. 91, p. 4427-4439 13 p.

Research output: Contribution to journalArticleScientificpeer-review

ANTISENSE INHIBITION OF LOW-AFFINITY NERVE GROWTH-FACTOR RECEPTOR IN KIDNEY CULTURES - POWER AND PITFALLS

SAINIO, K., SAARMA, M., NONCLERCQ, D., PAULIN, L. & SARIOLA, H., 1994, In : Cellular and Molecular Neurobiology. 14, p. 439-457 19 p.

Research output: Contribution to journalArticleScientificpeer-review