Department of Biochemistry and Developmental Biology

  • Finland

Publications 1980 2019

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2007

Binding of lysozyme to phospholipid bilayers: evidence for protein aggregation upon membrane association

Gorbenko, G., Ioffe, V. & Kinnunen, P., 2007, In : Biophysical Journal. 93, p. 140-153 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells

Tafesse, F. G., Huitema, K., Hermansson, M., Poel, S. V. D., Dikkenberg, J. V. D., Uphoff, A., Somerharju, P. & Holthuis, J., 2007, In : Journal of Biological Chemistry. 282, 24, p. 17537-17547 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Cdk8 is essential for preimplantation mouse development

Westerling, T., Kuuluvainen, E. & Mäkelä, T., 2007, In : Molecular and Cellular Biology. 27, 17, p. 6177-6182 6 p.

Research output: Contribution to journalArticleScientificpeer-review

c-Myc blazing a trail of death: coupling of the mitochondrial and death receptor apoptosis pathways by c-Myc

Nieminen, A., Partanen, J. & Klefström, J., 2007, In : Cell Cycle. 6, 20, p. 2464-2472 9 p.

Research output: Contribution to journalArticleScientificpeer-review

c-Myc primed mitochondria determine cellular sensitivity to TRAIL-induced apoptosis

Nieminen, A., Partanen, J., Hau, A. & Klefström, J., 2007, In : EMBO Journal. 26, p. 1055-1067 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Computational identification of candidate loci for recessively inherited mutation using high-throughput SNP arrays: genetics and population analysis

Laakso, M., Tuupanen, S., Karhu, A., Lehtonen, R., Aaltonen, L. A. & Hautaniemi, S., 2007, In : Bioinformatics. 23, 15, p. 1952-1961 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Decision tree modeling predicts effects of inhibiting contractility signaling on cell motility

Kharait, S., Hautaniemi, S., Wu, S., Iwabu, A., Lauffenburger, D. & Wells, A., 2007, In : BMC Systems Biology. 1, 9, 13 s

Research output: Contribution to journalArticleScientificpeer-review

Endocytic trafficking of sphingomyelin depends on its acyl chain length

Koivusalo, M., Jansen, M., Somerharju, P. & Ikonen, E., 2007, In : Molecular Biology of the Cell. 18, 12, p. 5113-5123 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Fluorescent temporin B derivative and its binding to liposomes

Sood, R., Domanov, Y. & Kinnunen, P., 2007, In : Journal of Fluorescence. 17, p. 223-234 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Glycogen synthase kinase-3 inactivation and stabilization of [beta]-catenin induce nephron differentiation in isolated mouse and rat kidney mesenchymes

Kuure, S., Popsueva, A., Jakobson, M., Sainio, K. & Sariola, H., 2007, In : Journal of the American Society of Nephrology. 18, p. 1130-1139 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Influence of the spacer of cationic gemini amphiphiles on the hydration of lipoplexes

Luciani, P., Bombelli, C., Colone, M., Giansanti, L., Ryhänen, S., Säily, V. M. J., Mancini, G. & Kinnunen, P., 2007, In : Biomacromolecules. 8, p. 1999-2003 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Interfacial and lipid transfer properties of human phospholipid transfer protein: implications for the transfer mechanism of phospholipids

Setälä, N. L., Metso, J., Wiedmer, S. K., Yohannes, G., Kinnunen, P. K. J., Ehnholm, C., Holopainen, J. & Jauhiainen, M., 2007, In : Biochemistry. 46, p. 1312-1319 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Interfacial and lipid transfer properties of human phospholipid transfer protein

Setälä, N., Metso, J., Wiedmer, S., Yohannes, G., Kinnunen, P., Ehnholm, C., Holopainen, J. & Jauhiainen, M., 2007, In : Chemistry and Physics of Lipids. 149, p. S88-S89 2 p.

Research output: Contribution to journalArticleScientificpeer-review

In vivo MRI reveals the dynamics of pathological changes in the brains of cathepsin D-deficient mice and correlates changes in manganese-enhanced MRI with microglial activation

Haapanen, A., Ramadan, U. A., Autti, T., Joensuu, R. & Tyynelä, J., 2007, In : Magnetic Resonance Imaging. 25, 7, p. 1024-1031 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Lipid metabolism in the adipose tissues of a carnivore, the raccoon dog, during prolonged fasting

Mustonen, A-M., Käkelä, R., Käkelä, A., Pyykönen, T., Aho, J. & Nieminen, P., 2007, In : Experimental Biology and Medicine (Maywood). 232, p. 58-69 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

Wolf-Yadlin, A., Hautaniemi, S., Lauffenburger, D. & White, F., 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 14, p. 5860-5865 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Neural network and "Ganglion" formations in vitro: A video Microscopy and scanning electron Microscopy study on adult cultured spiral ganglion cells

Bostroem, M., Anderson, M., Lindholm, D., Park, K-H., Schrott-Fischer, A., Pfaller, K., Glueckert, R. & Rask-Andersen, H., 2007, In : Otology & Neurotology. 28, p. 1109-1119 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Oxidized phospholipids as potential novel drug targets

Mattila, J-P., Sabatini, K. & Kinnunen, P., 2007, In : Biophysical Journal. 93, p. 3105-3112 8 p.

Research output: Contribution to journalArticleScientificpeer-review

PlasmaDNA: a free, cross-platform plasmid manipulation program for molecular biology laboratories

Angers-Loustau, A., Rainy, J. & Wartiovaara, K., 2007, In : BMC Molecular Biology. 8, 77, 5 s

Research output: Contribution to journalArticleScientificpeer-review

Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas

Sarek, G., Kurki, S., Enbäck, J., Iotzova, G., Haas, J., Laakkonen, P. M., Laiho, M. & Ojala, P., 2007, In : Journal of Clinical Investigation. 117, 4, p. 1019-1028 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Thalami and corona radiata in juvenile NCL (CLN3): a voxel-based morphometric study

Autti, T., Hämäläinen, J., Åberg, L., Lauronen, L., Tyynelä, J., van Leemput, K. & Åberg, L., 2007, In : European Journal of Neurology. 14, 4, p. 447-450 4 p.

Research output: Contribution to journalArticleScientificpeer-review

The LKB1 tumor suppressor kinase in human disease

Katajisto, P., Vallenius, T., Vaahtomeri, K., Ekman, N., Udd, L., Tiainen, M. & Makela, T. P., 2007, In : Biochimica et Biophysica Acta. Reviews on Cancer. 1775, 1, p. 63-75 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Thermal phase behavior of DMPG: the exclusion of continuous network and dense aggregates

Alakoskela, J-M. & Kinnunen, P., 2007, In : Langmuir. 23, p. 4203-4213 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Transcriptome teleonomy and scavenger lipidomics of albumin and alpha 1-acid glycoproteins: contextual genome-wide ontology enrichment as evidence for the epigenetic code?

Ojala, P., Kilpinen, S., Arola, L., Toronen, P., Bucher, E., Ojala, K., Iljin, K., Peltonen, M., Skotheim, R., Kleivi, K., Tolvanen, M., Autio, R., Somerharju, P., Kallioniemi, O. & Laitinen, S., Sep 2007, In : Chemistry and Physics of Lipids. 149, p. S86-S86 1 p.

Research output: Contribution to journalArticleScientificpeer-review

Viral oncogene-induced DNA damage response is activated in Kaposi sarcoma tumorigenesis

Koopal, S., Furuhjelm, J., Järviluoma, A., Jäämaa, S., Pyakurel, P., Pussinen, C. E., Wirzenius, M., Biberfeld, P., Alitalo, K., Laiho, M. & Ojala, P., 2007, In : PLoS Pathogens. 3, 9, p. 1348-1360 13 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

ABC lipid transporters: extruders, flippases, or flopless activators?

Meer, G. V., Halter, D., Sprong, H., Somerharju, P. & Egmond, M., 2006, In : FEBS Letters. 580, p. 1171-1177 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Altered distribution and levels of cathepsind and cystatins in amyotrophic lateral sclerosis transgenic mice: Possible roles in motor neuron survival

Wootz, H., Weber, E., Korhonen, L. & Lindholm, D., 2006, In : Neuroscience. 143, 2, p. 419-430 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Antimicrobial peptides temporins B and L induce formation of tubular lipid protrusions from supported phospholipid bilayers

Domanov, Y. & Kinnunen, P., 2006, In : Biophysical Journal. 91, p. 4427-4439 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Application of mass spectrometry to the determination of total antioxidant potential

Glod, B. K., Baumann, M. & Kaczmarski, K., 2006, In : Chemia Analityczna. 51, p. 51-64 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Biophysical properties of lipids and dynamic membranes

Janmey, P. A. & Kinnunen, P., 2006, In : Trends in Cell Biology. 16, 10, p. 538-546 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis

Siintola, E., Partanen, S., Strömme, P., Haapanen, A., Haltia, M., Maehlen, J., Lehesjoki, A-E. & Tyynelä, J., 2006, In : Brain : a journal of neurology. 129, p. 1438-1445 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Cationic lipid membranes: specific interactions with counter-ions

Ryhänen, S., Säily, V. M. J. & Kinnunen, P., 2006, In : Journal of Physics. Condensed Matter. 18, p. S1139-S1150

Research output: Contribution to journalArticleScientificpeer-review

Characteristics of fibers formed by cytochrome c and induced by anionic phospholipids

Alakoskela, J-M., Jutila, A., Simonsen, A., Pirneskoski, J., Pyhäjoki, S., Turunen, R., Marttila, S., Mouritsen, O., Goormaghtigh, E. & Kinnunen, P., 2006, In : Biochemistry. 45, p. 13447-13453 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of two oxidatively modified phospholipids in mixed monolayers with DPPC

Sabatini, K., Mattila, J-P., Megli, F. & Kinnunen, P., 2006, In : Biophysical Journal. 90, p. 4488-4499 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Cholesterol supports headgroup superlattice domain formation in fluid phospholipid/cholesterol bilayers

Cannon, B., Lewis, A., Metze, J., Thiagarajan, V., Vaughn, M., Somerharju, P., Virtanen, J., Huang, J. & Cheng, K. H., 2006, In : Journal of Physical Chemistry B. 110, 10, p. 6339-6350 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Counterion-controlled transition of a cationic gemini from submicroscopic to giant vesicles

Ryhänen, S., Säily, V. M. J., Parry, M., Luciani, P., Mancini, G., Alakoskela, J-M. & Kinnunen, P., 2006, In : Journal of the American Chemical Society. 128, p. 8659-8663 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Cytochrome C interaction with cardiolipin/phosphatidylcholine model membranes: effect of cardiolipin protonation

Gorbenko, G., Molotkovsky, J. & Kinnunen, P., 2006, In : Biophysical Journal. 90, p. 4093-4103 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Differential gene expression in non-malignant tumour microenvironment is associated with outcome in follicular lymphoma patients treated with rituximab and CHOP

Harjunpää, A., Taskinen, M., Nykter, M., Karjalainen-Lindsberg, M-L., Nyman, H., Monni, O., Hemmer, S., Yli-Harja, O., Hautaniemi, S., Meri, S. & Leppä, S., 2006, In : British Journal of Haematology. 135, 1, p. 33-42 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Divergence of hedgehog signal transduction mechanism between Drosophila and mammals

Varjosalo, M. T., Li, S. & Taipale, J., 2006, In : Developmental Cell. 10, p. 177-186 10 p.

Research output: Contribution to journalArticleScientificpeer-review

E6/E7 oncogenes increase and tumor suppressors decrease the proportion of self-renewing neural progenitor cells

Piltti, K., Kerosuo, L., Hakanen, J., Eriksson, M., Angers-Loustau, A., Leppä, S., Salminen, M., Sariola, H. & Wartiovaara, K., 2006, In : Oncogene. 25, p. 4880-4889 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

Wolf-Yadlin, A., Kumar, N., Zhang, Y., Hautaniemi, S., Zaman, M., Kim, H-D., Grantcharova, V., Lauffenburger, D. & White, F., 2006, In : Molecular Systems Biology. 2, 54, 15 p.

Research output: Contribution to journalArticleScientificpeer-review

ER stress and neurodegenerative diseases

Lindholm, D., Wootz, H. & Korhonen, L., 2006, In : Cell Death and Differentiation. 13, p. 385-392 8 p.

Research output: Contribution to journalArticleScientificpeer-review

From genes to systems: new global strategies for the characterization of NCL biology

Jalanko, A., Tyynelä, J. & Peltonen, L., 2006, In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1762, p. 934-944 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity

Hallikas, O., Palin, K., Sinjushina, N., Rautiainen, R., Partanen, J. M., Ukkonen, E. J. & Taipale, J., 2006, In : Cell. 124, 1, p. 47-59 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Herpesvirukset ja immuunijärjestelmä: virusperäisen syövän alkulähteillä : [katsaus]

Lehtonen, A. & Ojala, P., 2006, In : Duodecim. 122, p. 1759-1766 8 p.

Research output: Contribution to journalArticleScientific

High-throughput assay for determining specificity and affinity of protein-DNA binding interactions

Hallikas, O. & Taipale, J., 2006, In : Nature Protocols. 1, 1, p. 215-222 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification and analysis of a novel serine [beta]-lactamase-like plant protein by a bioinformatic approach

Liobikas, J., Baniulis, D., Stanys, V., Toleikis, A. & Eriksson, O., 2006, In : Biologija. 3, p. 126-129 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification and analysis of a novel serine β-lactamase-like plant protein by a bioinformatic approach

Eriksson-Rosenberg, O., Liobikas, J., Baniulis, D., Stanys, V. & Toleikis, A., 2006, In : Biologija. 3, p. 590-595

Research output: Contribution to journalArticleScientificpeer-review

Identification of pathways regulating cell size and cell-cycle progression by RNAi

Björklund, M., Taipale, M. K., Varjosalo, M. T., Saharinen, J., Lahdenperä, J. & Taipale, J., 2006, In : Nature. 439, p. 1009-1013 5 p.

Research output: Contribution to journalArticleScientificpeer-review