Department of Oncology

  • Finland

Publications 1991 2019

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2019
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8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia

Buettner, R., Le Xuan Truong Nguyen, Kumar, B., Morales, C., Liu, C., Chen, L. S., Pemovska, T., Synold, T. W., Palmer, J., Thompson, R., Li, L., Dinh Hoa Hoang, Zhang, B., Ghoda, L., Kowolik, C., Kontro, M., Leitch, C., Wennerberg, K., Yu, X., Chen, C-C. & 5 others, Horne, D., Gandhi, V., Pullarkat, V., Marcucci, G. & Rosen, S. T., Sep 2019, In : Journal of Cellular Physiology. 234, 9, p. 16295-16303 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Acute Lymphoblastic Leukemia With INPP5D-ABL1 Fusion Responds to Imatinib Treatment

Poukka, M., Lund-Aho, T., Raittinen, P., Nikkilä, A., Kivinen, K., Lundan, T., Porkka, K. & Lohi, O., Oct 2019, In : Journal of pediatric hematology/oncology. 41, 7, p. E481-E483 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia

Batcha, A. M. N., Bamopoulos, S. A., Kerbs, P., Kumar, A., Jurinovic, V., Rothenberg-Thurley, M., Ksienzyk, B., Philippou-Massier, J., Krebs, S., Blum, H., Schneider, S., Konstandin, N., Bohlander, S. K., Heckman, C., Kontro, M., Hiddemann, W., Spiekermann, K., Braess, J., Metzeler, K. H., Greif, P. A. & 2 others, Mansmann, U. & Herold, T., 13 Aug 2019, In : Scientific Reports. 9, 11 p., 11796.

Research output: Contribution to journalArticleScientificpeer-review

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Allogeneic Stem Cell Transplantation for Blast Crisis Chronic Myeloid Leukemia in the Era of Tyrosine Kinase Inhibitors: A Retrospective Study by the EBMT Chronic Malignancies Working Party

Radujkovic, A., Dietrich, S., Blok, H-J., Nagler, A., Ayuk, F., Finke, J., Tischer, J., Mayer, J., Koc, Y., Sora, F., Passweg, J., Byrne, J. L., Jindra, P., Veelken, J. H., Socie, G., Maertens, J., Schaap, N., Stadler, M., Itälä-Remes, M., Tholouli, E. & 6 others, Arat, M., Rocha, V., Ljungman, P., Yakoub-Agha, I., Kroeger, N. & Chalandon, Y., Oct 2019, In : Biology of Blood and Marrow Transplantation. 25, 10, p. 2008-2016 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Anagrelide for Gastrointestinal Stromal Tumor

Pulkka, O-P., Gebreyohannes, Y. K., Wozniak, A., Mpindi, J-P., Tynninen, O., Icay, K., Cervera, A., Keskitalo, S., Murumägi, A., Kulesskiy, E., Laaksonen, M., Wennerberg, K., Varjosalo, M., Laakkonen, P., Lehtonen, R., Hautaniemi, S., Kallioniemi, O., Schöffski, P., Sihto, H. & Joensuu, H., 1 Mar 2019, In : Clinical Cancer Research. 25, 5, p. 1676-1687 12 p.

Research output: Contribution to journalArticleScientificpeer-review

A Novel Anti-HER2 Antibody-Drug Conjugate XMT-1522 for HER2-Positive Breast and Gastric Cancers Resistant to Trastuzumab Emtansine

Le Joncour, V., Martins, A., Puhka, M., Isola, J., Salmikangas, M., Laakkonen, P., Joensuu, H. & Barok, M., Oct 2019, In : Molecular Cancer Therapeutics. 18, 10, p. 1721-1730 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Antikoagulaatiohoidon seuranta ja verenvuotokomplikaatiot

Lepäntalo, A., 2019, In : Suomen lääkärilehti. 74, 8, p. 469-472 4 p.

Research output: Contribution to journalArticleProfessional

Antilymphocyte globulin for matched sibling donor transplantation in patients with myelofibrosis

Robin, M., Chevret, S., Koster, L., Wolschke, C., Yakoub-Agha, I., Bourhis, J. H., Chevallier, P., Cornelissen, J. J., Remenyi, P., Maertens, J., Poire, X., Craddock, C., Socie, G., Itälä-Remes, M., Schouten, H. C., Marchand, T., Passweg, J., Blaise, D., Damaj, G., Ozkurt, Z. N. & 7 others, Zuckerman, T., Cluzeau, T., Labussiere-Wallet, H., Cammenga, J., McLornan, D., Chalandon, Y. & Kroger, N., 31 May 2019, In : Haematologica. 104, 6, p. 1230-1236 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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A prospective non-interventional study on the impact of transfusion burden and related iron toxicity on outcome in myelodysplastic syndromes undergoing allogeneic hematopoietic cell transplantation

Cremers, E. M. P., de Witte, T., de Wreede, L., Eikema, D-J., Koster, L., van Biezen, A., Finke, J., Socie, G., Beelen, D., Maertens, J., Nagler, A., Kobbe, G., Ziagkos, D., Itälä-Remes, M., Gedde-Dahl, T., Sierra, J., Niederwieser, D., Ljungman, P., Beguin, Y., Ozkurt, Z. N. & 4 others, Anagnostopoulos, A., Jindra, P., Robin, M. & Kröger, N., 10 Apr 2019, In : Leukemia & lymphoma. 10 p.

Research output: Contribution to journalArticleScientificpeer-review

A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease

Van Horebeek, L., Hilven, K., Mallants, K., Van Nieuwenhuijze, A., Kelkka, T., Savola, P., Mustjoki, S., Schlenner, S. M., Liston, A., Dubois, B. & Goris, A., 15 Apr 2019, In : Human Molecular Genetics. 28, 8, p. 1369-1380 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Assessing the utilization of the decision to implement a palliative goal for the treatment of cancer patients during the last year of life at Helsinki University Hospital: a historic cohort study

Hirvonen, O. M., Leskelä, R-L., Gronholm, L., Haltia, O., Rissanen, A., Tyynela-Korhonen, K., Rahko, E. K., Lehto, J. T. & Saarto, T., 5 Sep 2019, In : Acta Oncologica. 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

Breast Canc Assoc Consortium, NBCS Collaborators, Shu, X., Wu, L., Khankari, N. K., Blomqvist, C. & Nevanlinna, H., Jun 2019, In : International Journal of Epidemiology. 48, 3, p. 795-806 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Blood graft composition and post-transplant recovery in myeloma patients mobilized with plerixafor: a prospective multicenter study

Valtola, J., Silvennoinen, R., Ropponen, A., Siitonen, T., Säily, M., Sankelo, M., Putkonen, M., Partanen, A., Pyorälä, M., Savolainen, E-R., Mäntymaa, P., Pelkonen, J., Jantunen, E. & Varmavuo, V., 28 Jan 2019, In : Leukemia & lymphoma. 60, 2, p. 453-461 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Boron neutron capture therapy for locally recurrent head and neck squamous cell carcinoma: An analysis of dose response and survival

Koivunoro, H., Kankaanranta, L., Seppälä, T., Haapaniemi, A., Mäkitie, A. & Joensuu, H., Aug 2019, In : Radiotherapy and Oncology. 137, p. 153-158 6 p.

Research output: Contribution to journalArticleScientificpeer-review

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Breast cancer outcome prediction with tumour tissue images and machine learning

Turkki, R., Byckhov, D., Lundin, M., Isola, J., Nordling, S., Kovanen, P. E., Verrill, C., von Smitten, K., Joensuu, H., Lundin, J. & Linder, N., Aug 2019, In : Breast Cancer Research and Treatment. 177, 1, p. 41-52 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Cancer Patients' Symptom Burden and Health-related Quality of Life (HRQoL) at Tertiary Cancer Center from 2006 to 2013: A Cross-sectional Study

Kokkonen, K., Tasmuth, T., Lehto, J. T., Kautiainen, H., Elme, A., Jaaskelainen, A-S. & Saarto, T., Jan 2019, In : Anticancer Research. 39, 1, p. 271-277 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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CAR-T-soluhoito - mitä ja millä hinnalla?

Leppä, S. & Vettenranta, K., 2019, In : Duodecim. 135, 12, p. 1202-1206 5 p.

Research output: Contribution to journalArticleProfessional

Characterization of an X-chromosome-linked telomere biology disorder in females with DKC1 mutation

Hirvonen, E. A. M., Peuhkuri, S., Norberg, A., Degerman, S., Hannula-Jouppi, K., Välimaa, H., Kilpivaara, O. & Wartiovaara-Kautto, U., Jan 2019, In : Leukemia. 33, 1, p. 275-278 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of polydactyly chondrocytes and their use in cartilage engineering

Cavalli, E., Levinson, C., Hertl, M., Broguiere, N., Brück, O., Mustjoki, S., Gerstenberg, A., Weber, D., Salzmann, G., Steinwachs, M., Barreto, G. & Zenobi-Wong, M., 12 Mar 2019, In : Scientific Reports. 9, 15 p., 4275.

Research output: Contribution to journalArticleScientificpeer-review

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Clinical and morphological practices in the diagnosis of transplant-associated microangiopathy: a study on behalf of Transplant Complications Working Party of the EBMT

Moiseev, I. S., Tsvetkova, T., Aljurf, M., Alnounou, R. M., Bogardt, J., Chalandon, Y., Drokov, M. Y., Dvirnyk, V., Faraci, M., Friis, L. S., Giglio, F., Greinix, H. T., Kornblit, B. T., Koelper, C., Koenecke, C., Lewandowski, K., Niederwieser, D., Passweg, J. R., Peczynski, C., Penack, O. & 15 others, Peric, Z., Piekarska, A., Ronchi, P. E., Rovo, A., Rzepecki, P., Scuderi, F., Sigrist, D., Siitonen, S. M., Stoelzel, F., Sulek, K., Tsakiris, D. A., Wilkowojska, U., Duarte, R. F., Ruutu, T. & Basak, G. W., Jul 2019, In : Bone Marrow Transplantation. 54, 7, p. 1022-1028 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Clinical features and outcome of the patients with sinonasal tract diffuse large B-cell lymphoma in the pre-rituximab and rituximab eras

Vähämurto, P., Mannisto, S., Pollari, M., Karjalainen-Lindsberg, M-L., Mäkitie, A. A. & Leppä, S., Jun 2019, In : European Journal of Haematology. 102, 6, p. 457-464 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Comparable Long-Term Outcome after Allogeneic Stem Cell Transplantation from Sibling and Matched Unrelated Donors in Patients with Acute Myeloid Leukemia Older Than 50 Years: A Report on Behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation

Shimoni, A., Labopin, M., Savani, B., Byrne, M., Volin, L., Finke, J., Niederwieser, D., Ehninger, G., Blaise, D., Beelen, D., Tabrizi, R., Sengeloev, H., Ganser, A., Cornelissen, J. J., Mohty, M. & Nagler, A., Nov 2019, In : Biology of Blood and Marrow Transplantation. 25, 11, p. 2251-2260 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Comparing modular and personal service delivery in specialised outpatient care: A survey of haematology and oncology patient preferences

Silander, K., Torkki, P., Peltokorpi, A., Tarkkanen, M., Lepäntalo, A., Mattson, J., Bono, P. & Kaila, M., Nov 2019, In : Health Services Management Research. 32, 4, p. 209-217 9 p., 0951484819868681.

Research output: Contribution to journalArticleScientificpeer-review

Comparison of FLAMSA-based reduced intensity conditioning with treosulfan/fludarabine conditioning for patients with acute myeloid leukemia: an ALWP/EBMT analysis

Sheth, V., Labopin, M., Canaani, J., Volin, L., Brecht, A., Ganser, A., Mayer, J., Labussiere-Wallet, H., Bittenbring, J., Shouval, R., Savani, B., Mohty, M. & Nagler, A., Apr 2019, In : Bone Marrow Transplantation. 54, 4, p. 531-539 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Computational Analysis of HLA-presentation of Non-synonymous Recipient Mismatches Indicates Effect on the Risk of Chronic Graft-vs.-Host Disease After Allogeneic HSCT

Ritari, J., Hyvärinen, K., Koskela, S., Niittyvuopio, R., Nihtinen, A., Salmenniemi, U., Putkonen, M., Volin, L., Kwan, T., Pastinen, T., Itälä-Remes, M. & Partanen, J., 16 Jul 2019, In : Frontiers in Immunology. 10, 9 p., 1625.

Research output: Contribution to journalArticleScientificpeer-review

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Constitutively active GSK3 beta as a means to bolster dendritic cell functionality in the face of tumor-mediated immune suppression

Gonzalez, M. L., Oosterhoff, D., Lindenberg, J. J., Milenova, I., Lougheed, S. M., Martianez, T., Dekker, H., Quixabeira, D. C. A., Hangalapura, B., Joore, J., Piersma, S. R., Cervera-Carrascon, V., Santos, J. M., Scheper, R. J., Verheul, H. M. W., Jimenez, C. R., Van De Ven, R., Hemminki, A., Van Beusechem, V. W. & De Gruijl, T. D., 3 Oct 2019, In : OncoImmunology. 8, 10, 18 p., e1631119.

Research output: Contribution to journalArticleScientificpeer-review

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Costs in Different States of Breast Cancer

Roine, E., Farkkila, N., Sintonen, H., Taari, K., Roine, R. P. & Saarto, T., Jan 2019, In : Anticancer Research. 39, 1, p. 353-359 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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Craniomaxillofacial osteosarcoma - The role of surgical margins

Kontio, R., Hagström, J., Lindholm, P., Böhling, T., Sampo, M., Mesimäki, K., Saarilahti, K., Koivunen, P. & Mäkitie, A. A., Jun 2019, In : Journal of Cranio-Maxillo-Facial Surgery. 47, 6, p. 922-925 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Dasatinib and navitoclax act synergistically to target NUP98-NSD1(+)/FLT3-ITD+ acute myeloid leukemia

Kivioja, J. L., Thanasopoulou, A., Kumar, A., Kontro, M., Yadav, B., Majumder, M. M., Javarappa, K. K., Eldfors, S., Schwaller, J., Porkka, K. & Heckman, C. A., Jun 2019, In : Leukemia. 33, 6, p. 1360-1372 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Data-driven characterization of molecular phenotypes across heterogeneous sample collections

Mehtonen, J., Polonen, P., Häyrynen, S., Dufva, O., Lin, J., Liuksiala, T., Granberg, K., Lohi, O., Hautamäki, V., Nykter, M. & Heinäniemi, M., 26 Jul 2019, In : Nucleic Acids Research. 47, 13, 12 p., 76.

Research output: Contribution to journalArticleScientificpeer-review

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Differences in the risk of stroke, bleeding events, and mortality between female and male patients with atrial fibrillation during warfarin therapy

Penttilä, T., Lehto, M., Niiranen, J., Mehtälä, J., Khanfir, H., Lassila, R. & Raatikainen, P., Jan 2019, In : European Heart Journal - Cardiovascular Pharmacotherapy. 5, 1, p. 29-36 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Distinct subtypes of diffuse large B-cell lymphoma defined by hypermutated genes

Alkodsi, A., Cervera, A., Zhang, K., Louhimo, R., Meriranta, L., Pasanen, A., Leivonen, S-K., Holte, H., Leppä, S., Lehtonen, R. & Hautaniemi, S., Nov 2019, In : Leukemia. 33, 11, p. 2662-2672 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Does Decision-making in End-of-life Care Differ Between Graduating Medical Students and Experienced Physicians?

Alminoja, A., Piili, R. P., Hinkka, H., Metsänoja, R., Hirvonen, O., Tyynelä-Korhonen, K., Kaleva-Kerola, J., Saarto, T., Kellokumpu-Lehtinen, P-L. I. & Lehto, J. T., 2019, In : In Vivo. 33, 3, p. 903-909 7 p.

Research output: Contribution to journalArticleScientificpeer-review

EBMT prospective observational study on allogeneic hematopoietic stem cell transplantation in T-prolymphocytic leukemia (T-PLL)

Wiktor-Jedrzejczak, W., Drozd-Sokolowska, J., Eikema, D. J., Hoek, J., Potter, M., Wulf, G., Sellner, L., Ljungman, P., Chevallier, P., Volin, L., Koc, Y., Martin, S., Bunjes, D., Rovira, M., Itala-Remes, M., Foa, R., Deconinck, E., Gedde-Dahl, T., Cornelissen, J., Collin, M. & 12 others, Brecht, A., Patel, A., de Groot, M., Remenyi, P., Nagler, A., Finke, J., Turlure, P., Iacobelli, S., van Biezen, A., Schetelig, J., Kroeger, N. & Dreger, P., Sep 2019, In : Bone Marrow Transplantation. 54, 9, p. 1391-1398 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Effectiveness of a 12-month Exercise Intervention on Physical Activity and Quality of Life of Breast Cancer Survivors; Five-year Results of the BREX-study

Penttinen, H., Utriainen, M., Kellokumpu-Lehtinen, P-L., Raitanen, J., Sievänen, H., Nikander, R., Blomqvist, C., Huovinen, R., Vehmanen, L. & Saarto, T., 2019, In : In Vivo. 33, 3, p. 881-888 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of Genetic Modifications on Physical and Functional Titers of Adenoviral Cancer Gene Therapy Constructs

Heiniö, C., Sorsa, S., Siurala, M., Grönberg-Vähä-Koskela, S., Havunen, R., Haavisto, E., Koski, A., Hemminki, O., Zafar, S., Cervera-Carrascon, V., Munaro, E., Kanerva, A. & Hemminki, A., 1 Jun 2019, In : Human Gene Therapy. 30, 6, p. 740-752 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of Wilms tumor histology on response to neoadjuvant chemotherapy

Taskinen, S., Leskinen, O., Lohi, J., Koskenvuo, M. & Taskinen, M., Apr 2019, In : Journal of Pediatric Surgery. 54, 4, p. 771-774 4 p.

Research output: Contribution to journalArticleScientificpeer-review

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Estrogen receptor beta expression correlates with proliferation in desmoid tumors

Santti, K., Ihalainen, H., Rönty, M., Karlsson, C., Haglund, C., Sampo, M., Tarkkanen, M. & Blomqvist, C., Jun 2019, In : Journal of Surgical Oncology. 119, 7, p. 873-879 7 p.

Research output: Contribution to journalArticleScientificpeer-review

European Society of Surgical Oncology's strategy for clinical research: Paving the way for a culture of research in cancer surgery

European Soc Surgical Oncology, Sep 2019, In : European Journal of Surgical Oncology. 45, 9, p. 1515-1519 5 p.

Research output: Contribution to journalArticleScientificpeer-review

EUSOMA position regarding breast implant associated anaplastic large cell lymphoma (BIA-ALCL) and the use of textured implants

Cardoso, M. J., Wyld, L., Rubio, I. T., Leidenius, M., Curigliano, G., Cutuli, B., Marotti, L. & Biganzoli, L., Apr 2019, In : Breast. 44, p. 90-93 4 p.

Research output: Contribution to journalArticleScientificpeer-review

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Evaluation of risk factors for oral infection with potential for spread in a 1-year cohort study

Farkkila, E., Rautemaa-Richardson, R., Färkkilä, A., Grönholm, L. & Lauhio, A., Feb 2019, In : Clinical Oral Investigations. 23, 2, p. 905-911 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Evolving Clinical Picture of Renal Cell Carcinoma: A Population-Based Study from Helsinki

Erkkilä, K., Tornberg, S. V., Järvinen, P., Järvinen, R., Kilpeläinen, T. P., Visapää, H., Hervonen, P., Taari, K. & Nisen, H., 2019, In : Urologia internationalis. 102, 4, p. 390-398 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Extent of Resection and Long-Term Survival of Pineal Region Tumors in Helsinki Neurosurgery

Choque-Velasquez, J., Resendiz-Nieves, J., Jahromi, B. R., Colasanti, R., Raj, R., Vehviläinen, J., Tynninen, O., Collan, J., Niemelä, M. & Hernesniemi, J., Nov 2019, In : World Neurosurgery. 131, p. E379-E391 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Familial Associations of Colon and Rectal Cancers With Other Cancers

Yu, H., Hemminki, A., Sundquist, K. & Hemminki, K., Feb 2019, In : Diseases of the Colon & Rectum. 62, 2, p. 189-195 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Family Mismatched Allogeneic Stem Cell Transplantation for Myelofibrosis: Report from the Chronic Malignancies Working Party of European Society for Blood and Marrow Transplantation

Raj, K., Eikema, D-J., McLornanl, D. P., Olavarria, E., Bloke, H-J., Bregante, S., Ciceri, F., Passweg, J., Ljungman, P., Schaap, N., Carlson, K., Zuckerman, T., de Wreede, L. C., Volin, L., Koc, Y., Luis Diez-Martin, J., Brossart, P., Wolf, D., Blaise, D., Di Bartolomeo, P. & 5 others, Vitek, A., Robin, M., Yakoub-Agha, I., Chalandon, Y. & Kroger, N., Mar 2019, In : Biology of Blood and Marrow Transplantation. 25, 3, p. 522-528 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Feasibility of MRI-only photon and proton dose calculations for pediatric patients with abdominal tumors

Guerreiro, F., Koivula, L., Seravalli, E., Janssens, G. O., Maduro, J. H., Brouwer, C. L., Korevaar, E. W., Knopf, A. C., Korhonen, J. & Raaymakers, B. W., Mar 2019, In : Physics in Medicine and Biology. 64, 5, 13 p., 055010.

Research output: Contribution to journalArticleScientificpeer-review

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Functional Outcome Measurement in Patients with Lower-Extremity Soft Tissue Sarcoma: A Systematic Literature Review

Kask, G., Barner-Rasmussen, I., Repo, J. P., Kjäldman, M., Kilk, K., Blomqvist, C. & Tukiainen, E. J., 12 Aug 2019, In : Annals of Surgical Oncology.

Research output: Contribution to journalArticleScientificpeer-review

Open Access