Department of Pharmacology

  • Finland

Publications 1982 2019

2019

Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy

Rajendran, J., Purhonen, J., Tegelberg, S., Smolander, O-P., Mörgelin, M., Rozman, J., Gailus-Durner, V., Fuchs, H., de Angelis, M. H., Auvinen, P., Mervaala, E., Jacobs, H. T., Szibor, M., Fellman, V. & Kallijärvi, J., Jan 2019, In : EMBO molecular medicine. 11, 1, 19 p., 9456.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Attenuation of Novelty-Induced Hyperactivity of Gria1-/- Mice by Cannabidiol and Hippocampal Inhibitory Chemogenetics

Aitta-aho, T., Maksimovic, M., Dahl, K., Sprengel, R. & Korpi, E. R., 29 Mar 2019, In : Frontiers in Pharmacology. 10, 11 p., 309.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

CACNG2 polymorphisms associate with chronic pain following mastectomy

Bortsov, A. V., Devor, M., Kaunisto, M. A., Kalso, E., Brufsky, A., Kehlet, H., Aasvang, E., Bittner, R., Diatchenko, L. & Belfer, I., Mar 2019, In : Pain. 160, 3, p. 561-568 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Caution in the Postoperative Treatment of Pain With Opioids-Surgeon Awareness Needed

Kalso, E., Puolakkainen, P. & Salminen, P., Apr 2019, In : JAMA surgery. 154, 4, 1 p., e185839.

Research output: Contribution to journalEditorialScientific

Combination of perineural and wound infusion after above knee amputation: A randomized, controlled multicenter study

FinAPain-1 Study Grp, von Plato, H., Peltoniemi, M., Kauhanen, P., Löyttyniemi, E., Hamunen, K. & Kontinen, V., Nov 2019, In : Acta Anaesthesiologica Scandinavica. 63, 10, p. 1406-1412 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Detection of human rhinoviruses by reverse transcription strand invasion based amplification method (RT-SIBA)

Kainulainen, V., Elf, S., Susi, P., Mäki, M., Pitkäranta, A., Koskinen, J. O., Korpela, R. & Eboigbodin, K. E., Jan 2019, In : Journal of Virological Methods. 263, p. 75-80 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

Lilius, T. O., Blomqvist, K., Hauglund, N., Liu, G., Stæger, F. F., Bærentzen, S., Du, T., Ahlström, F., Backman, J. T., Kalso, E., Rauhala, P. V. & Nedergaard, M., 28 Jun 2019, In : Journal of Controlled Release. 304, p. 29-38 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site

Selberg, S., Blokhina, D., Aatonen, M., Koivisto, P., Siltanen, A., Mervaala, E., Kankuri, E. & Karelson, M., 26 Mar 2019, In : Cell Reports. 26, 13, p. 3762-+ 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Dopaminergic-GABAergic interplay and alcohol binge drinking

Leggio, G. M., Di Marco, R., Gulisano, W., D'Ascenzo, M., Torrisi, S. A., Geraci, F., Lavanco, G., Dahl, K., Giurdanella, G., Castorina, A., Aitta-aho, T., Aceto, G., Bucolo, C., Puzzo, D., Grassi, C., Korpi, E. R., Drago, F. & Salomone, S., Mar 2019, In : Pharmacological Research. 141, p. 384-391 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Douleur Neuropathique 4 (DN4) stratifies possible and definite neuropathic pain after surgical peripheral nerve lesion

Aho, T., Mustonen, L., Kalso, E. & Harno, H., 12 Nov 2019, In : European Journal of Pain. 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of Donor Simvastatin Treatment on Gene Expression Profiles in Human Cardiac Allografts during Ischemia-Reperfusion Injury

Krebs, R., Kankainen, M., Holmström, E., Dhaygude, K., Lukac, J., Ojala, T., Mattila, P., Nykänen, A. & Lemström, K., Apr 2019, In : Journal of Heart and Lung Transplantation. 38, 4, Supplement, p. S75-S76

Research output: Contribution to journalConference articleScientificpeer-review

GABA(B) receptor positive allosteric modulators with different efficacies affect neuroadaptation to and self-administration of alcohol and cocaine

de Miguel, E., Vekovischeva, O., Kuokkanen, K., Vesajoki, M., Paasikoski, N., Kaskinoro, J., Myllymäki, M., Lainiola, M., Janhunen, S. K., Hyytiä, P., Linden, A-M. & Korpi, E. R., Nov 2019, In : Addiction Biology. 24, 6, p. 1191-1203 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Health-related quality of life change in patients treated at a multidisciplinary pain clinic

Vartiainen, P., Heiskanen, T., Sintonen, H., Roine, R. P. & Kalso, E., Aug 2019, In : European Journal of Pain. 23, 7, p. 1318-1328 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Ketamine in Pain Therapy

Bell, R. F. & Kalso, E. A., Apr 2019, In : Schmerz. 33, 2, p. 156-164 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Kivun olemusta etsimässä

Kalso, E., 2019, In : Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti.. 22, 2, p. 51 1 p.

Research output: Contribution to journalArticleProfessional

Lääketieteellinen farmakologia ja toksikologia

Ruskoaho, H. (ed.), Hakkola, J. (ed.), Huupponen, R. (ed.), Kantele, A. (ed.), Korpi, E. (ed.), Moilanen, E. (ed.), Piepponen, P. (ed.), Savontaus, E., Tenhunen, O. (ed.), Vähäkangas, K. & Anttila, V-J., 2019, 5. uud. p. ed. Helsinki: Duodecim. 1288 p.

Research output: Book/ReportBookProfessional

Lactose digestion in humans: intestinal lactase appears to be constitutive whereas the colonic microbiome is adaptable

Forsgård, R. A., Aug 2019, In : American Journal of Clinical Nutrition. 110, 2, p. 273-279 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File

Machine-learned analysis of global and glial/opioid intersection-related DNA methylation in patients with persistent pain after breast cancer surgery

Kringel, D., Kaunisto, M. A., Kalso, E. & Lötsch, J., 27 Nov 2019, In : Clinical epigenetics. 11, 1, 15 p., 167.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice

Galli, E., Rossi, J., Neumann, T., Andressoo, J-O., Drinda, S. & Lindholm, P., 4 Oct 2019, In : Scientific Reports. 9, 12 p., 14318.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Milk and milk-derived peptides combat against hypertension and vascular dysfunction: a review

Siltari, A., Vapaatalo, H. & Korpela, R., Jun 2019, In : International Journal of Food Science and Technology. 54, 6, p. 1920-1929 10 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access

Multiple actions of fenamates and other nonsteroidal anti-inflammatory drugs on GABA(A) receptors

Mansikkamäki, S., Sinkkonen, S. T., Korpi, E. R. & Lüddens, H., 15 Jun 2019, In : European Journal of Pharmacology. 853, p. 247-255 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Normal extinction and reinstatement of morphine-induced conditioned place preference in the GluA1-KO mouse line

Kiiskinen, T., Korpi, E. R. & Aitta-aho, T., Aug 2019, In : Behavioural Pharmacology. p. 405-411 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Oksikodonin ja fentanyylin käyttö avohoidossa

Kalso, E., Klintrup, K., Kastarinen, H., Saastamoinen, L., Helminen, S. & Välimäki, J., 2019, In : Suomen hammaslääkärilehti. 26, 7, p. 36-38 3 p.

Research output: Contribution to journalArticleProfessional

Oksikodonin ja fentanyylin käyttö avohoidossa

Kalso, E., Klintrup, K., Kastarinen, H., Saastamoinen, L., Helminen, S. & Välimäki, J., 2019, In : Suomen lääkärilehti. 74, 23, p. 1512-1514 3 p.

Research output: Contribution to journalArticleProfessional

Pain interference type and level guide the assessment process in chronic pain: Categorizing pain patients entering tertiary pain treatment with the Brief Pain Inventory

Miettinen, T., Kautiainen, H., Mantyselka, P., Linton, S. J. & Kalso, E., 20 Aug 2019, In : PLoS One. 14, 8, 15 p., 0221437.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
Open Access
File

Simultaneous Detection of Morphine and Codeine in the Presence of Ascorbic Acid and Uric Acid and in Human Plasma at Nafion Single-Walled Carbon Nanotube Thin-Film Electrode

Wester, N., Mynttinen, E., Etula, J., Lilius, T., Kalso, E., Kauppinen, E. I., Laurila, T. & Koskinen, J., 29 Oct 2019, In : ACS Omega. 4, 18, p. 17726-17734 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Simultaneous electrochemical detection of tramadol and O-desmethyltramadol with Nafion-coated tetrahedral amorphous carbon electrode

Mynttinen, E., Wester, N., Lilius, T., Kalso, E., Koskinen, J. & Laurila, T., 1 Feb 2019, In : Electrochimica Acta. 295, p. 347-353 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Systematic review of analgesics and dexamethasone for post-tonsillectomy pain in adults

Tolska, H. K., Hamunen, K., Takala, A. & Kontinen, V. K., Aug 2019, In : British Journal of Anaesthesia. 123, 2, p. E397-E411 15 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File

The opioid agonist remifentanil increases subjective pleasure

Heiskanen, T., Leppä, M., Suvilehto, J., Elomaa, M., Akural, E., Larinkoski, T., Jääskeläinen, I., Sams, M., Nummenmaa, L. & Kalso, E., Jun 2019, In : British Journal of Anaesthesia. 122, 6, p. E216-E219 5 p.

Research output: Contribution to journalLetterScientificpeer-review

The relationship between anger regulation, mood, pain, and pain-related disability in women treated for breast cancer

Sipilä, R., Hintsa, T., Lipsanen, J., Tasmuth, T., Estlander, A-M. & Kalso, E., Oct 2019, In : Psycho-Oncology. 28, 10, p. 2002-2008 7 p.

Research output: Contribution to journalArticleScientificpeer-review

The use of unlicensed bone marrow-derived platelet lysate-expanded mesenchymal stromal cells in colitis: a pre-clinical study

Salmenkari, H., Laitinen, A., Forsgård, R. A., Holappa, M., Linden, J., Pasanen, L., Korhonen, M., Korpela, R. & Nystedt, J., Feb 2019, In : Cytotherapy. 21, 2, p. 175-188 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Toimiiko sähköinen tentti lääkiksessä?

Siirilä, S., Merenmies, J., Pyörälä, E., Masalin, T., Baumann, M., Mervaala, E., Härkönen, T. & Rostila, A., 2019, In : Suomen lääkärilehti. 74, 43, p. 2457-2458 2 p.

Research output: Contribution to journalArticleProfessional

Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague-Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles

Forsgård, R. A., Marrachelli, V. G., Linden, J., Frias, R., Carmen Collado, M., Korpela, R., Monleon, D., Spillmann, T. & Österlund, P., Aug 2019, In : Translational oncology. 12, 8, p. 1122-1130 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Uutta tietoa terapeuttisesta vuorovaikutuksesta eli lumevasteesta

Kalso, E., 2019, In : Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti.. 22, 1, p. 44-45 2 p.

Research output: Contribution to journalArticleProfessional

What makes surgical nerve injury painful? A 4-year to 9-year follow-up of patients with intercostobrachial nerve resection in women treated for breast cancer

Mustonen, L., Aho, T., Harno, H., Sipilä, R., Meretoja, T. & Kalso, E., Jan 2019, In : Pain. 160, 1, p. 246-256 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
2018

Addiction-related interactions of pregabalin with morphine in mice and humans: reinforcing and inhibiting effects

Vashchinkina, E., Piippo, O., Vekovischeva, O., Krupitsky, E., Ilyuk, R., Neznanov, N., Kazankov, K., Zaplatkin, I. & Korpi, E. R., May 2018, In : Addiction Biology. 23, 3, p. 945-958 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Addiktion neurobiologia

Hyytiä, P., 2018, In : Duodecim. 134, 20, p. 2031-2038 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File

Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target

Dufva, O., Kankainen, M., Kelkka, T., Sekiguchi, N., Awad, S. A., Eldfors, S., Yadav, B., Kuusanmäki, H., Malani, D., Andersson, E. I., Pietarinen, P., Saikko, L., Kovanen, P. E., Ojala, T., Lee, D. A., Loughran, T. P., Nakazawa, H., Suzumiya, J., Suzuki, R., Ko, Y. H. & 7 others, Kim, W. S., Chuang, S-S., Aittokallio, T., Chan, W. C., Ohshima, K., Ishida, F. & Mustjoki, S., 19 Apr 2018, In : Nature Communications. 9, 12 p., 1567.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

A machine-learned analysis of human gene polymorphisms modulating persisting pain points to major roles of neuroimmune processes

Kringel, D., Lippmann, C., Parnham, M. J., Kalso, E., Ultsch, A. & Lötsch, J., Nov 2018, In : European Journal of Pain. 22, 10, p. 1735-1756 22 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

A microfluidic oxygen sink to create a targeted cellular hypoxic microenvironment under ambient atmospheric conditions

Barmaki, S., Jokinen, V., Obermaier, D., Blokhina, D., Korhonen, M., Ras, R. H. A., Vuola, J., Franssila, S. & Kankuri, E., Jun 2018, In : Acta Biomaterialia. 73, p. 167-179 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Analgesic Plasma Concentrations of Oxycodone After Surgery for Breast CancerWhich Factors Matter?

Cajanus, K., Neuvonen, M., Koskela, O., Kaunisto, M. A., Neuvonen, P. J., Niemi, M. & Kalso, E., Apr 2018, In : Clinical Pharmacology and Therapeutics. 103, 4, p. 653-662 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Analysis of Mitochondrial Protein Synthesis: De Novo Translation, Steady‐State Levels, and Assembled OXPHOS Complexes

Hilander, T., Konovalova, S., Terzioglu, M. & Tyynismaa, H., 31 Jul 2018, In : Current Protocols in Toxicology. 77, 1, e56.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Anestesiologit omalääkäreinä muuttuvassa maailmassa

Kalso, E., 2018, In : Finnanest.. 51, 1, p. 8 1 p.

Research output: Contribution to journalArticleProfessional

Open Access
File

Antihypertensive drugs and prostate cancer risk in a Finnish population-based cohort

Siltari, A., Murtola, T. J., Talala, K., Taari, K., Tammela, T. L. J. & Auvinen, A., 2 Nov 2018, In : Scandinavian Journal of Urology. 52, 5-6, p. 321-327 7 p.

Research output: Contribution to journalArticleScientificpeer-review