Publications 1992 2019

2019

Kainate receptor auxiliary subunit NETO2 is required for normal fear expression and extinction

Mennesson, M., Rydgren, E., Lipina, T., Sokolowska, E., Kulesskaya, N., Morello, F., Ivakine, E., Voikar, V., Risbrough, V., Partanen, J. & Hovatta, I., Oct 2019, In : Neuropsychopharmacology. 44, 11, p. 1855-1866 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2018

A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions

Nikkanen, J., Landoni, J. C., Balboa, D., Haugas, M., Partanen, J., Paetau, A., Isohanni, P., Brilhante, V. & Suomalainen, A., Jan 2018, In : EMBO molecular medicine. 10, 1, p. 13-21 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes

Balboa, D., Saarimäki-Vire, J., Borshagovski, D., Survila, M., Lindholm, P., Galli, E., Eurola, S., Ustinov, J., Grym, H., Huopio, H., Partanen, J., Wartiovaara, K. & Otonkoski, T., 9 Nov 2018, In : eLife. 7, 35 p., 38519.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Targeted deletion of RIC8A in mouse neural precursor cells interferes with the development of the brain, eyes, and muscles

Kask, K., Tikker, L., Ruisu, K., Lulla, S., Oja, E-M., Meier, R., Raid, R., Velling, T., Tonissoo, T. & Pooga, M., Apr 2018, In : Developmental Neurobiology. 78, 4, p. 374-390 17 p.

Research output: Contribution to journalArticleScientificpeer-review

2017

Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool

Zega, K., Jovanovic, V. M., Vitic, Z., Niedzielska, M., Knaapi, L., Jukic, M. M., Partanen, J., Friedel, R. F., Lang, R. & Brodski, C., 9 Nov 2017, In : Frontiers in Molecular Neuroscience. 10, 15 p., 372.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Inactivation of GATA cofactors Fog1 and Fog2 impairs the development of midbrain GABAergic neurons

Tikker, L., Lahti, L. S., Estartús, N. & Partanen, J. M., Jul 2017, p. S94. 1 p.

Research output: Conference materialsAbstractResearch

Open Access

Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta

Rice, R., Cebra-Thomas, J., Haugas, M., Partanen, J., Rice, D. P. C. & Gilbert, S. F., 21 Sep 2017, In : Scientific Reports. 7, 11 p., 12063.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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NETO1 Guides Development of Glutamatergic Connectivity in the Hippocampus by Regulating Axonal Kainate Receptors.

Orav, E., Atanasova, T., Shintyapina, A., Kesaf, S., Kokko, M., Partanen, J. M., Taira, T. P. & Lauri, S. E., 3 Jul 2017, In : eNeuro. 4, 3, 17 p., e0048-17.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2016

A recessive syndrome of intellectual disability, moderate overgrowth, and renal dysplasia predisposing to Wilms tumor is caused by a mutation in FIBP gene

Akawi, N., Ben-Salem, S., Lahti, L., Partanen, J., Ali, B. R. & Al-Gazali, L., Aug 2016, In : American Journal of Medical Genetics. Part A. 170, 8, p. 2111-2118 8 p.

Research output: Contribution to journalArticleScientificpeer-review

c-Jun N-Terminal Phosphorylation: Biomarker for Cellular Stress Rather than Cell Death in the Injured Cochlea.

Anttonen, T. M., Herranen, H. A-R., Virkkala, J., Kirjavainen, A. L., Elomaa, P., Laos, M., Liang, X., Ylikoski, J., Behrens, A. & Pirvola, U. H., 24 May 2016, In : eNeuro. 3, 2, 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei

Lahti, L., Haugas, M., Tikker, L., Airavaara, M., Voutilainen, M., Anttila, J., Kumar, S., Inkinen, C., Salminen, M. & Partanen, J., 1 Feb 2016, In : Development. 143, 3, p. 516-529 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe

Haugas, M., Tikker, L., Achim, K., Salminen, M. H. & Partanen, J. M., 2016, In : Development. 143, 23, p. 4495-4508 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Peroxidase-Generated Apoplastic ROS Impair Cuticle Integrity and Contribute to DAMP-Elicited Defenses

Survila, M., Davidsson, P. R., Pennanen, V., Kariola, T., Broberg, M., Sipari, N., Heino, P. & Palva, E. T., 23 Dec 2016, In : Frontiers in plant science. 7, 16 p., 1945.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus

Jager, P., Ye, Z., Yu, X., Zagoraiou, L., Prekop, H-T., Partanen, J., Jessell, T. M., Wisden, W., Brickley, S. G. & Delogu, A., 8 Dec 2016, In : Nature Communications. 7, 14 p., 13579.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2015

Diversity and development of local inhibitory and excitatory neurons associated with dopaminergic nuclei

Morello, F. & Partanen, J., 21 Dec 2015, In : FEBS Letters. 589, 24, p. 3693-3701 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Kehitysbiologia : solusta yksilöksi

Sariola, H., Frilander, M., Heino, T., Jernvall, J., Partanen, J., Sainio, K., Salminen, M., Thesleff, I. & Wartiovaara, K., 2015, 2. uud. p. ed. Helsinki: Kustannus Oy Duodecim. 340 p.

Research output: Book/ReportBookScientificpeer-review

The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea

Kirjavainen, A., Laos, M., Anttonen, T. & Pirvola, U., 15 Apr 2015, In : Biology open. 4, 4, p. 516-526 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2014

Mechanisms regulating GABAergic neuron development

Achim, K., Salminen, M. & Partanen, J., 2014, In : Cellular and Molecular Life Sciences. 71, 8, p. 1395-1415 21 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

Molecular regulation of GABAergic neuron differentiation and diversity in the developing midbrain

Lahti, L., Achim, K. & Partanen, J., 2013, In : Acta Physiologica. 207, 4, p. 616-627 12 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors.

Achim, K., Peltopuro, P. P., Lahti, L. S., Tsai, H-H., Zachariah, A., Åstrand, M., Salminen, M., Rowitch, D. & Partanen, J., 2013, In : Biology open. 2, p. 990-997 8 p., bio.20135041v1.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2012

Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain

Lahti, L. S., Peltopuro, P. P., Piepponen, T. P. & Partanen, J., 2012, In : Development. 139, 5, p. 894-905 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Distinct developmental origins and regulatory mechanisms for GABAergic neurons associated with dopaminergic nuclei in the ventral mesodiencephalic region

Achim, K., Peltopuro, P., Lahti, L., Li, J., Salminen, M. & Partanen, J., 2012, In : Development. 139, 13, p. 2360-2370 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Fgf8-Related Secondary Organizers Exert Different Polarizing Planar Instructions along the Mouse Anterior Neural Tube

Crespo-Enriquez, I., Partanen, J., Martinez, S. & Echevarria, D., 6 Jul 2012, In : PLoS One. 7, 7, p. e39977 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres

Virolainen, S-M., Achim, K., Peltopuro, P., Salminen, M. & Partanen, J., 15 Oct 2012, In : Development. 139, 20, p. 3795-3805 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Analysis of Cdh22 expression and function in the developing mouse brain

Saarimäki-Vire, J. M., Alitalo, A. & Partanen, J., 2011, In : Developmental Dynamics. 240, 8, p. 1989-2001 13 p.

Research output: Contribution to journalArticleScientificpeer-review

FGF signaling gradient maintains symmetrical proliferative divisions of midbrain neuronal progenitors.

Lahti, L. S., Saarimäki-Vire, J. M., Rita, H. & Partanen, J., 2011, In : Developmental Biology. 349, 2, p. 270-282 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Phosphorylated beta-catenin localizes to centrosomes of neuronal progenitors and is required for cell polarity and neurogenesis in developing midbrain

Chilov, D., Sinjushina, N., Rita, H., Taketo, M. M., Makela, T. P. & Partanen, J., 2011, In : Developmental Biology. 357, 1, p. 259-268 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Phosphorylated β-catenin localizes to centrosomes of neuronal progenitors and is required for cell polarity and neurogenesis in developing midbrain

Chilov, D., Sinjushina, N., Rita, H., Taketo, M. M., Mäkelä, T. & Partanen, J., 2011, In : Developmental Biology. 357, 1, p. 259-268

Research output: Contribution to journalArticleScientificpeer-review

2010

Beta-Catenin Regulates Intercellular Signalling Networks and Cell-Type Specific Transcription in the Developing Mouse Midbrain-Rhombomere 1 Region

Chilov, D., Sinjushina, N., Saarimäki-Vire, J. M., Taketo, M. M. & Partanen, J., 2010, In : PLoS One. 5, 6, p. e10881 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons

Peltopuro, P., Kala, K. & Partanen, J., 2010, In : Developmental Biology. 343, 1-2, p. 63-70 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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FGF receptors 1 and 2 control chemically induced injury and compound detoxification in regenerating livers of mice.

Böhm, F., Speicher, T., Hellerbrand, C., Dickson, C., Partanen, J., Ornitz, D. & Werner, S., 2010, In : Gastroenterology. 139, 4, p. 1385-1396, e8 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis

Yang, J., Meyer, M., Mueller, A-K., Boehm, F., Grose, R., Dauwalder, T., Verrey, F., Kopf, M., Partanen, J., Bloch, W., Ornitz, D. M. & Werner, S., 2010, In : Journal of Cell Biology. 188, 6, p. 935-952 18 p.

Research output: Contribution to journalArticleScientificpeer-review

2009

Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons

Kala, K., Haugas, M., Lilleväli, K., Guimera, J., Wurst, W., Salminen, M. & Partanen, J., 2009, In : Development. 136, 2, p. 253-262 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Transposition-based method for the rapid generation of gene-targeting vectors to produce Cre/Flp-modifiable conditional knock-out mice

Turakainen, H., Saarimäki-Vire, J., Sinjushina, N., Partanen, J. & Savilahti, H., 2009, In : PLoS One. 4, 2, p. e4341 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2008

Analysis of the midbrain-hindbrain boundary cell fate using a boundary cell-specific Cre-mouse strain

Kala, K., Jukkola, T., Pata, I. & Partanen, J., 2008, In : Genesis: the journal of genetics and development. 46, 1, p. 29-36 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Developmental origin of smooth muscle cells in the descending aorta in mice

Wasteson, P., Johansson, B. R., Jukkola, T., Breuer, S., Akyurek, L. M., Partanen, J. & Lindahl, P., 2008, In : Development. 135, 10, p. 1823-1832 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain

Blak, A. A., Naserke, T., Saarimäki-Vire, J., Peltopuro, P., Giraldo-Velasquez, M., Vogt Weisenhorn, D. M., Prakash, N., Sendtner, M., Partanen, J. & Wurst, W., 2007, In : Developmental Biology. 303, p. 231-243 13 p.

Research output: Contribution to journalArticleScientificpeer-review

FGF signalling pathways in development of the midbrain and anterior hindbrain

Partanen, J., 2007, In : Journal of Neurochemistry. 101, p. 1185-1193 9 p.

Research output: Contribution to journalArticleScientific

Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain

Saarimäki-Vire, J., Peltopuro, P., Lahti, L., Naserke, T., Blak, A. A., Vogt Weisenhorn, D. M., Yu, K., Ornitz, D. M., Wurst, W. & Partanen, J., 2007, In : Journal of Neuroscience. 27, 32, p. 8581-8592 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Targeted deletion of the muscular dystrophy gene myotilin does not perturb muscle structure or function in mice

Moza, M., Mologni, L., Trokovic, R., Faulkner, G., Partanen, J. & Carpen, O., 2007, In : Molecular and Cellular Biology. 27, 1, p. 244-252 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region

Jukkola, T., Lahti, L., Naserke, T., Wurst, W. & Partanen, J., 2006, In : Developmental Biology. 297, p. 141-157 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in mice

Zhao, H., Yang, Y., Partanen, J., Ciruna, BG., Rossant, J. & Robinson, M. L., 2006, In : Molecular Vision. 12, p. 15-25

Research output: Contribution to journalArticleScientificpeer-review

Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation

Jacob, A. L., Smith, C., Partanen, J. & Ornitz, D. M., 2006, In : Developmental Biology. 296, p. 315-328 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity

Hallikas, O., Palin, K., Sinjushina, N., Rautiainen, R., Partanen, J. M., Ukkonen, E. J. & Taipale, J., 2006, In : Cell. 124, 1, p. 47-59 13 p.

Research output: Contribution to journalArticleScientificpeer-review

2005

Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo

Lavine, K. J., Yu, K., White, A. C., Zhang, X., Smith, C., Partanen, J. M. & Ornitz, D. M., 2005, In : Developmental Cell. 8, p. 85-95 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Expression of Fgf receptors 1, 2, and 3 in the developing mid- and hindbrain of the mouse

Blak, A. A., Naserke, T., Weisenhorn, D. M. V., Prakash, N., Partanen, J. M. & Wurst, W., 2005, In : Developmental Dynamics. 233, 3, p. 1023-1030 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Fgfr1-dependent boundary cells between developing mid- and hindbrain

Trokovic, R., Jukkola, T., Saarimäki, J., Peltopuro, P., Naserke, T., Vogt Weisenhorn, D. M., Trokovic, N., Wurst, W. & Partanen, J. M., 2005, In : Developmental Biology. 278, 2, p. 428-439 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development

Magnusson, P. U., Ronca, R., Dell Era, P., Carlstedt, P., Jakobsson, L., Partanen, J. M., Dimberg, A. & Claesson-Welsh, L., 2005, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 25, 5, p. 944-949 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Fibroblast growth factor signalling and regional specification of the pharyngeal ectoderm

Trokovic, N., Trokovic, R. & Partanen, J., 2005, In : International Journal of Developmental Biology. 49, 7, p. 797-805 9 p.

Research output: Contribution to journalArticleScientificpeer-review