Developmental Psychology Research Group

  • Haartmaninkatu 3, Medicum, 2nd Floor

    00290 Helsinki

    Finland

Publications

2020

Associations of antenatal glucocorticoid exposure with mental health in children

Wolford, E., Lahti-Pulkkinen, M., Girchenko, P., Lipsanen, J., Tuovinen, S., Lahti, J., Heinonen, K., Hämäläinen, E., Kajantie, E., Pesonen, A-K., Villa, P. M., Laivuori, H., Reynolds, R. M. & Räikkönen, K., Jan 2020, In : Psychological Medicine. 50, 2, p. 247-257 11 p., 0033291718004129.

Research output: Contribution to journalArticleScientificpeer-review

Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis

Yeung, E. H., Guan, W., Zeng, X., Salas, L. A., Mumford, S. L., de Prado Bert, P., van Meel, E. R., Malmberg, A., Sunyer, J., Duijts, L., Felix, J. F., Czamara, D., Hämäläinen, E., Binder, E. B., Räikkönen, K., Lahti, J., London, S. J., Silver, R. M. & Schisterman, E. F., 30 Apr 2020, In : Clinical epigenetics. 12, 10 p., 60.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

Merid, S. K., Novoloaca, A., Sharp, G. C., Kupers, L. K., Kho, A. T., Roy, R., Gao, L., Annesi-Maesano, I., Jain, P., Plusquin, M., Kogevinas, M., Allard, C., Vehmeijer, F. O., Kazmi, N., Salas, L. A., Rezwan, F. I., Zhang, H., Sebert, S., Czamara, D., Rifas-Shiman, S. L. & 73 others, Melton, P. E., Lawlor, D. A., Pershagen, G., Breton, C. V., Huen, K., Baiz, N., Gagliardi, L., Nawrot, T. S., Corpeleijn, E., Perron, P., Duijts, L., Nohr, E. A., Bustamante, M., Ewart, S. L., Karmaus, W., Zhao, S., Page, C. M., Herceg, Z., Jarvelin, M-R., Lahti, J., Baccarelli, A. A., Anderson, D., Kachroo, P., Relton, C. L., Bergstrom, A., Eskenazi, B., Soomro, M. H., Vineis, P., Snieder, H., Bouchard, L., Jaddoe, V. W., Sorensen, T. I. A., Vrijheid, M., Arshad, S. H., Holloway, J. W., Haberg, S. E., Magnus, P., Dwyer, T., Binder, E. B., DeMeo, D. L., Vonk, J. M., Newnham, J., Tantisira, K. G., Kull, I., Wiemels, J. L., Heude, B., Sunyer, J., Nystad, W., Munthe-Kaas, M. C., Raikkonen, K., Oken, E., Huang, R-C., Weiss, S. T., Anto, J. M., Bousquet, J., Kumar, A., Soderhall, C., Almqvist, C., Cardenas, A., Gruzieva, O., Xu, C-J., Reese, S. E., Kere, J., Brodin, P., Solomon, O., Wielscher, M., Holland, N., Ghantous, A., Hivert, M-F., Felix, J. F., Koppelman, G. H., London, S. J. & Melen, E., 2 Mar 2020, In : Genome medicine. 12, 1, 17 p., 25.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium

Howe, C. G., Cox, B., Fore, R., Jungius, J., Kvist, T., Lent, S., Miles, H. E., Salas, L. A., Rifas-Shiman, S., Starling, A. P., Yousefi, P., Ladd-Acosta, C., Baccarelli, A., Binder, E. B., Chatzi, V. L., Czamara, D., Dabelea, D., DeMeo, D. L., Ghantous, A., Herceg, Z. & 18 others, Kajantie, E., Lahti, J. M. T., Lawlor, D. A., Litonjua, A., Nawrot, T. S., Nohr, E. A., Oken, E., Pizzi, C., Plusquin, M., Räikkönen, K., Relton, C. L., Sharp, G. C., Sorensen, T. I. A., Sunyer, J., Vrijheid, M., Zhang, W., Hivert, M-F. & Breton, C. V., Jan 2020, In : Diabetes Care. 43, 1, p. 98-105 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Mental Health Outcomes of Adults Born Very Preterm or with Very Low Birth Weight: A systematic review

Robinson, R., Lahti-Pulkkinen, M., Schnitzlein, D., Voit, F., Girchenko, P., Wolke, D., Lemola, S., Kajantie, E., Heinonen, K. & Räikkönen, K., 28 Apr 2020, In : Seminars in Fetal & Neonatal Medicine.

Research output: Contribution to journalArticleScientificpeer-review

Polygenic impact of morningness on the overnight dynamics of sleep spindle amplitude

Pesonen, A-K., Merikanto, I., Halonen, R., Ujma, P., Makkonen, T., Räikkönen, K., Lahti, J. & Kuula, L., 17 Jan 2020, In : Genes, Brain and Behavior. 9 p., 12641.

Research output: Contribution to journalArticleScientificpeer-review

Reaction times, learning, and executive functioning in adults born preterm

Suikkanen, J., Miettola, S., Heinonen, K., Vääräsmäki, M., Tikanmäki, M., Sipola, M., Matinolli, H-M., Järvelin, M-R., Räikkönen, K., Hovi, P. & Kajantie, E., 19 Mar 2020, In : Pediatric Research. 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

Munn-Chernoff, M. A., Johnson, E. C., Chou, Y-L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S., Giusti-Rodríguez, P. & 332 others, Hanscombe, K. B., Adan, R. A. H., Alfredsson, L., Ando, T., Andreassen, O. A., Berrettini, W. H., Boehm, I., Boni, C., Boraska Perica, V., Buehren, K., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Cone, R. D., Courtet, P., Crow, S., Crowley, J. J., Danner, U. N., Davis, O. S. P., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Dmitrzak-Weglarz, M., Docampo, E., Duncan, L. E., Egberts, K., Ehrlich, S., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Favaro, A., Fernández-Aranda, F., Fichter, M. M., Fischer, K., Föcker, M., Foretova, L., Forstner, A. J., Forzan, M., Franklin, C. S., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Gratacos Mayora, M., Guillaume, S., Guo, Y., Hakonarson, H., Hatzikotoulas, K., Hauser, J., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Huckins, L. M., Hudson, J. I., Imgart, H., Inoko, H., Janout, V., Jiménez-Murcia, S., Julià, A., Kalsi, G., Kaminská, D., Karhunen, L., Karwautz, A., Kas, M. J. H., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Kim, Y-R., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Levitan, R. D., Li, D., Lilenfeld, L., Lin, B. D., Lissowska, J., Luykx, J., Magistretti, P. J., Maj, M., Mannik, K., Marsal, S., Marshall, C. R., Mattingsdal, M., McDevitt, S., McGuffin, P., Metspalu, A., Meulenbelt, I., Micali, N., Mitchell, K., Monteleone, A. M., Monteleone, P., Nacmias, B., Navratilova, M., Ntalla, I., O'Toole, J. K., Ophoff, R. A., Padyukov, L., Palotie, A., Pantel, J., Papezova, H., Pinto, D., Rabionet, R., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Santonastaso, P., Scherag, A., Scherer, S. W., Schmidt, U., Schork, N. J., Schosser, A., Seitz, J., Slachtova, L., Slagboom, P. E., Slof-Op't Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Szatkiewicz, J. P., Tachmazidou, I., Tenconi, E., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Wagner, G., Walton, E., Widen, E., Zeggini, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, T., Whiteman, D. C., Woodside, D. B., Grove, J., Henders, A. K., Larsen, J. T., Parker, R., Petersen, L. V., Jordan, J., Kennedy, M. A., Birgegård, A., Lichtenstein, P., Norring, C., Landén, M., Mortensen, P. B., Polimanti, R., McClintick, J. N., Adkins, A. E., Aliev, F., Bacanu, S-A., Batzler, A., Bertelsen, S., Biernacka, J. M., Bigdeli, T. B., Chen, L-S., Clarke, T-K., Degenhardt, F., Docherty, A. R., Edwards, A. C., Foo, J. C., Fox, L., Frank, J., Hack, L. M., Hartmann, A. M., Hartz, S. M., Heilmann-Heimbach, S., Hodgkinson, C., Hoffmann, P., Hottenga, J-J., Konte, B., Lahti, J., Lahti-Pulkkinen, M., Lai, D., Ligthart, L., Loukola, A., Maher, B. S., Mbarek, H., McIntosh, A. M., McQueen, M. B., Meyers, J. L., Milaneschi, Y., Palviainen, T., Peterson, R. E., Ryu, E., Saccone, N. L., Salvatore, J. E., Sanchez-Roige, S., Schwandt, M., Sherva, R., Streit, F., Strohmaier, J., Thomas, N., Wang, J-C., Webb, B. T., Wedow, R., Wetherill, L., Wills, A. G., Zhou, H., Boardman, J. D., Chen, D., Choi, D-S., Copeland, W. E., Culverhouse, R. C., Dahmen, N., Degenhardt, L., Domingue, B. W., Frye, M. A., Gäbel, W., Hayward, C., Ising, M., Keyes, M., Kiefer, F., Koller, G., Kramer, J., Kuperman, S., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Männistö, S., Müller-Myhsok, B., Murray, A. D., Nurnberger, J. I., Preuss, U., Räikkönen, K., Reynolds, M. D., Ridinger, M., Scherbaum, N., Schuckit, M. A., Soyka, M., Treutlein, J., Witt, S. H., Wodarz, N., Zill, P., Adkins, D. E., Boomsma, D. I., Bierut, L. J., Brown, S. A., Bucholz, K. K., Costello, E. J., de Wit, H., Diazgranados, N., Eriksson, J. G., Farrer, L. A., Foroud, T. M., Gillespie, N. A., Goate, A. M., Goldman, D., Grucza, R. A., Hancock, D. B., Harris, K. M., Hesselbrock, V., Hewitt, J. K., Hopfer, C. J., Iacono, W. G., Johnson, E. O., Karpyak, V. M., Kendler, K. S., Kranzler, H. R., Krauter, K., Lind, P. A., McGue, M., MacKillop, J., Madden, P. A. F., Maes, H. H., Magnusson, P. K. E., Nelson, E. C., Nöthen, M. M., Palmer, A. A., Penninx, B. W. J. H., Porjesz, B., Rice, J. P., Rietschel, M., Riley, B. P., Rose, R. J., Shen, P-H., Silberg, J., Stallings, M. C., Tarter, R. E., Vanyukov, M. M., Vrieze, S., Wall, T. L., Whitfield, J. B., Zhao, H., Neale, B. M., Wade, T. D., Heath, A. C., Montgomery, G. W., Martin, N. G., Sullivan, P. F., Kaprio, J., Breen, G., Gelernter, J., Edenberg, H. J., Bulik, C. M. & Agrawal, A., 16 Feb 2020, In : Addiction Biology. 20 p., 12880.

Research output: Contribution to journalArticleScientificpeer-review

Aging, cognitive ability and the risk of dementia in the Helsinki Birth Cohort Study

Rantalainen, V., 22 Mar 2019, Helsinki: University of Helsinki. 92 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Open Access

Antipsychotic Use Among 1144 Patients After Aneurysmal Subarachnoid Hemorrhage A Population-Based Case-Control Study

Paavola, J. T., Väntti, N., Junkkari, A., Huttunen, T. J., von und zu Fraunberg, M., Koivisto, T., Kämäräinen, O-P., Lång, M., Meretoja, A., Räikkönen, K., Viinamäki, H., Jääskeläinen, J. E., Huttunen, J. & Lindgren, A. E., Jul 2019, In : Stroke. 50, 7, p. 1711-1718 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Associations of autozygosity with a broad range of human phenotypes

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T. M. & 416 others, Baumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J-F., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., Van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., de Haan, H. G., Harris, S. E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-Gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., van der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., van der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Alberto Aguilar-Salinas, C., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., de Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M-L., Chen, G., Chen, Y-D. I., Chen, Z., Chiu, Y-F., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., Van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Doerr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdottir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gogele, M., Goodarzi, M. O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. A., Halevy, A., Harris, T. B., Hedayati, M., van Heel, D. A., Hirata, M., Hofer, I., Hsiung, C. A., Huang, J., Hung, Y-J., Ikram, M. A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N. D., Kessler, T., Khaw, K-T., Khor, C. C., de Kleijn, D. P. V., Koh, W-P., Kolcic, I., Kraft, P., Kramer, B. K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L. J., Lawlor, D. A., Lee, I-T., Lee, W-J., Lerch, M. M., Li, L., Liu, J., Loh, M., London, S. J., Loomis, S., Lu, Y., Luan, J., Magi, R., Manichaikul, A. W., Manunta, P., Masson, G., Matoba, N., Mei, X. W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I. Y., Momozawa, Y., Moore, A., Morange, P-E., Moreno-Macias, H., Mori, T. A., Morrison, A. C., Muka, T., Murakami, Y., Murray, A. D., de Mutsert, R., Mychaleckyj, J. C., Nalls, M. A., Nauck, M., Neville, M. J., Nolte, I. M., Ong, K. K., Orozco, L., Padmanabhan, S., Palsson, G., Pankow, J. S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P. P., Quintana-Murci, L., Räikkönen, K., Ralhan, S., Rao, D. C., van Rheenen, W., Rich, S. S., Ridker, P. M., Rietveld, C. A., Robino, A., van Rooij, F. J. A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-Lleal, M., Felicita Sala, C., Salomaa, V., Sandow, K., Schmidt, H., Scott, L. J., Scott, W. R., Sedaghati-Khayat, B., Sennblad, B., van Setten, J., Sever, P. J., Sheu, W. H-H., Shi, Y., Shrestha, S., Shukla, S. R., Sigurdsson, J. K., Sikka, T. T., Singh, J. R., Smith, B. H., Stancakova, A., Stanton, A., Starr, J. M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M. A., Taylor, A. M., Taylor, K. D., Terzikhan, N., Tham, Y-C., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R. P., Tusie-Luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J. H., Vitart, V., Volker, U., Vuoksimaa, E., Wakil, S. M., Waldenberger, M., Wander, G. S., Wang, Y. X., Wareham, N. J., Wild, S., Yajnik, C. S., Yuan, J-M., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Becker, D. M., Lehne, B., Bennett, D. A., van den Berg, L. H., Berndt, S. I., Bharadwaj, D., Bielak, L. F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J. P., Brody, J. A., Campbell, A., Carmi, S., Caulfield, M. J., Cesarini, D., Chambers, J. C., Chandak, G. R., Cheng, C-Y., Ciullo, M., Cornelis, M., Cusi, D., Smith, G. D., Deary, I. J., Dorajoo, R., van Duijn, C. M., Ellinghaus, D., Erdmann, J., Eriksson, J. G., Evangelou, E., Evans, M. K., Faul, J. D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S. F. A., Griffiths, L. R., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., van der Harst, P., Heng, C-K., Hicks, A. A., Hochner, H., Huikuri, H., Hunt, S. C., Jaddoe, V. W. V., De Jager, P. L., Johannesson, M., Johansson, A., Jonas, J. B., Jukema, J. W., Junttila, J., Kaprio, J., Kardia, S. L. R., Karpe, F., Kumari, M., Laakso, M., van der Laan, S. W., Lahti, J., Laudes, M., Lea, R. A., Lieb, W., Lumley, T., Martin, N. G., Marz, W., Matullo, G., McCarthy, M. I., Medland, S. E., Merriman, T. R., Metspalu, A., Meyer, B. F., Mohlke, K. L., Montgomery, G. W., Mook-Kanamori, D., Munroe, P. B., North, K. E., Nyholt, D. R., O'connell, J. R., Ober, C., Oldehinkel, A. J., Palmas, W., Palmer, C., Pasterkamp, G. G., Patin, E., Pennell, C. E., Perusse, L., Peyser, P. A., Pirastu, M., Polderman, T. J. C., Porteous, D. J., Posthuma, D., Psaty, B. M., Rioux, J. D., Rivadeneira, F., Rotimi, C., Rotter, J. I., Rudan, I., Den Ruijter, H. M., Sanghera, D. K., Sattar, N., Schmidt, R., Schulze, M. B., Schunkert, H., Scott, R. A., Shuldiner, A. R., Sim, X., Small, N., Smith, J. A., Sotoodehnia, N., Tai, E-S., Teumer, A., Timpson, N. J., Toniolo, D., Tregouet, D-A., Tuomi, T., Vollenweider, P., Wang, C. A., Weir, D. R., Whitfield, J. B., Wijmenga, C., Wong, T-Y., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 31 Oct 2019, In : Nature Communications. 10, 17 p., 4957.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Autistic traits and sleep in typically developing adolescents

Salmela, L., Kuula, L., Merikanto, I., Räikkönen, K. & Pesonen, A-K., Feb 2019, In : Sleep Medicine. 54, p. 164-171 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Autistic Traits Are Associated With Decreased Activity of Fast Sleep Spindles During Adolescence

Merikanto, I., Kuula, L., Makkonen, T., Salmela, L., Räikkönen, K. & Pesonen, A-K., 2019, In : Journal of clinical sleep medicine . 15, 3, p. 401-407 7 p.

Research output: Contribution to journalArticleScientificpeer-review

C9orf72 hexanucleotide repeat length in older population: normal variation and effects on cognition

Kaivola, K., Kiviharju, A., Jansson, L., Rantalainen, V., Eriksson, J. G., Strandberg, T. E., Laaksovirta, H., Renton, A. E., Traynor, B. J., Myllykangas, L. & Tienari, P., Dec 2019, In : Neurobiology of Aging. 84, p. 242.e7-242.e12 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Consequences of being overweight or obese during pregnancy on diabetes in the offspring: a record linkage study in Aberdeen, Scotland

Lahti-Pulkkinen, M., Bhattacharya, S., Wild, S. H., Lindsay, R. S., Räikkönen, K., Norman, J. E., Bhattacharya, S. & Reynolds, R. M., Aug 2019, In : Diabetologia. 62, 8, p. 1412-1419 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Depression, daylight and diabetes : shared genetic background and genomic moderation of associations

Haljas, K., 2019, Helsinki : [K. Haljas]. 77 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Disentangling the genetics of lean mass

Karasik, D., Zillikens, M. C., Hsu, Y-H., Aghdassi, A., Akesson, K., Amin, N., Barroso, I., Bennett, D. A., Bertram, L., Bochud, M., Borecki, I. B., Broer, L., Buchman, A. S., Byberg, L., Campbell, H., Campos-Obando, N., Cauley, J. A., Cawthon, P. M., Chambers, J. C., Chen, Z. & 137 others, Cho, N. H., Choi, H. J., Chou, W-C., Cummings, S. R., de Groot, L. C. P. G. M., De Jager, P. L., Demuth, I., Diatchenko, L., Econs, M. J., Eiriksdottir, G., Enneman, A. W., Eriksson, J., Eriksson, J. G., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Gieger, C., Grallert, H., Gudnason, V., Lenore, L. J., Hayward, C., Hofman, A., Homuth, G., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J-O., Johnson, T., Biffar, R., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K-T., Kilpelainen, T. O., Klopp, N., Kloth, J. S. L., Koller, D. L., Kooner, J. S., Kraus, W. E., Kritchevsky, S., Kutalik, Z., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Lerch, M. M., Lewis, J. R., Lill, C., Lind, L., Lindgren, C., Liu, Y., Livshits, G., Ljunggren, O., Loos, R. J. F., Lorentzon, M., Luan, J., Luben, R. N., Malkin, I., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellstrom, D., Michaelsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Nethander, M., Newman, A. B., O'Connell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Peacock, M., Perola, M., Peters, A., Prince, R. L., Psaty, B. M., Räikkönen, K., Ralston, S. H., Ripatti, S., Rivadeneira, F., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schipf, S., Shin, C. S., Smith, A. V., Smith, S. B., Soranzo, N., Spector, T. D., Stancakova, A., Stefansson, K., Steinhagen-Thiessen, E., Stolk, L., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Thompson, P., Thomson, C. A., Thorleifsson, G., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Uitterlinden, A. G., van Duijn, C. M., van Schoor, N. M., Vandenput, L., Vollenweider, P., Volzke, H., Wactawski-Wende, J., Walker, M., Wareham, N. J., Waterworth, D., Weedon, M. N., Wichmann, H-E., Widen, E., Williams, F. M. K., Wilson, J. F., Wright, N. C., Yerges-Armstrong, L. M., Yu, L., Zhang, W., Zhao, J. H., Zhou, Y., Nielson, C. M., Harris, T. B., Demissie, S., Kiel, D. P. & Ohlsson, C., Feb 2019, In : American Journal of Clinical Nutrition. 109, 2, p. 276-287 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of maternal lifestyle interventions on child neurobehavioral development: Follow-up of randomized controlled trials

Menting, M. D., van de Beek, C., Rono, K., Hoek, A., Groen, H., Painter, R. C., Girchenko, P., Lahti-Pulkkinen, M., Koivusalo, S. B., Raikkonen, K., Eriksson, J. G., Roseboom, T. J. & Heinonen, K., Dec 2019, In : Scandinavian Journal of Psychology. 60, 6, p. 548-558 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappa B-driven inflammation and cardiovascular risk

Zannas, A. S., Jia, M., Hafner, K., Baumert, J., Wiechmann, T., Pape, J. C., Arloth, J., Ködel, M., Martinelli, S., Roitman, M., Roeh, S., Haehle, A., Emeny, R. T., Iurato, S., Carrillo-Roa, T., Lahti, J., Räikkönen, K., Eriksson, J. G., Drake, A. J., Waldenberger, M. & 13 others, Wahl, S., Kunze, S., Lucae, S., Bradley, B., Gieger, C., Hausch, F., Smith, A. K., Ressler, K. J., Mueller-Myhsok, B., Ladwig, K-H., Rein, T., Gassen, N. C. & Binder, E. B., 4 Jun 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 23, p. 11370-11379 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Epigenome-wide meta-analysis of DNA methylation and childhood asthma

BIOS Consortium, Reese, S. E., Xu, C-J., den Dekker, H. T., Lahti, J., Kajantie, E., Kere, J. & Räikkönen, K., Jun 2019, In : Journal of Allergy and Clinical Immunology. 143, 6, p. 2062-2074 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Fetal programming of neuropsychiatric disorders by maternal pregnancy depression: a systematic mini review

Robinson, R., Lahti-Pulkkinen, M., Heinonen, K., Reynolds, R. M. & Räikkönen, K., Jan 2019, In : Pediatric Research. 85, 2, p. 134-145 12 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

23and Me Res Team, eQTLGen Consortium, Int Cannabis Consortium, Soc Sci Genetic Association Con, Linner, R. K., Perola, M., Ripatti, S., Gupta, R., Lahti, J., Eklund, N., Koskinen, S., Latvala, A., Loukola, A., Mäki-Opas, T., Palotie, A., Sarin, A-P., Räikkönen, K., Eriksson, J. G., Kaprio, J., Perola, M. & 3 others, Salomaa, V., Kaasik, K. & Keltikangas-Järvinen, L., Feb 2019, In : Nature Genetics. 51, 2, p. 245-+ 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals

Liu, C-T., Merino, J., Rybin, D., DiCorpo, D., Benke, K. S., Bragg-Gresham, J. L., Canouil, M., Corre, T., Grallert, H., Isaacs, A., Kutalik, Z., Lahti, J., Marullo, L., Marzi, C., Rasmussen-Torvik, L. J., Rocheleau, G., Rueedi, R., Scapoli, C., Verweij, N., Vogelzangs, N. & 30 others, Willems, S. M., Yengo, L., Bakker, S. J. L., Beilby, J., Hui, J., Kajantie, E., Müller-Nurasyid, M., Rathmann, W., Balkau, B., Bergmann, S., Eriksson, J. G., Florez, J. C., Froguel, P., Harris, T., Hung, J., James, A. L., Kavousi, M., Miljkovic, I., Musk, A. W., Palmer, L. J., Peters, A., Roussel, R., van der harst, P., van Duijn, C. M., Vollenweider, P., Barroso, I., Prokopenko, I., Dupuis, J., Meigs, J. B. & Bouatia-Naji, N., 1 Jul 2019, In : Scientific Reports. 9, 1, 8 p., 9439.

Research output: Contribution to journalArticleScientificpeer-review

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Gestational Diabetes But Not Prepregnancy Overweight Predicts for Cardiometabolic Markers in Offspring Twenty Years Later

Kaseva, N., Vääräsmäki, M., Sundvall, J., Matinolli, H-M., Sipola, M., Tikanmäki, M., Heinonen, K., Lano, A., Wehkalampi, K., Wolke, D., Ruokonen, A., Andersson, S., Järvelin, M-R., Räikkönen, K., Eriksson, J. G. & Kajantie, E., Jul 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2785-2795 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation

Provençal, N., Arloth, J., Cattaneo, A., Anacker, C., Cattane, N., Wiechmann, T., Röh, S., Ködel, M., Klengel, T., Czamara, D., Müller, N. S., Lahti, J., Räikkönen, K., Pariante, C. M. & Binder, E. B., 9 Aug 2019, In : Proceedings of the National Academy of Sciences of the United States of America.

Research output: Contribution to journalArticleScientificpeer-review

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Higher sleep spindle activity is associated with fewer false memories in adolescent girls

Kuula, L., Tamminen, J., Makkonen, T., Merikanto, I., Räikkönen, K. & Pesonen, A-K., Jan 2019, In : Neurobiology of Learning and Memory. 157, p. 96-105 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns Findings From the Pregnancy and Childhood Epigenetics Consortium

Kazmi, N., Sharp, G. C., Reese, S. E., Vehmeijer, F. O., Lahti, J., Page, C. M., Zhang, W., Rifas-Shiman, S. L., Rezwan, F. I., Simpkin, A. J., Burrows, K., Richardson, T. G., Ferreira, D. L. S., Fraser, A., Harmon, Q. E., Zhao, S., Jaddoe, V. W. V., Czamara, D., Binder, E. B., Magnus, M. C. & 23 others, Haberg, S. E., Nystad, W., Nohr, E. A., Starling, A. P., Kechris, K. J., Yang, I. V., DeMeo, D. L., Litonjua, A. A., Baccarelli, A., Oken, E., Holloway, J. W., Karmaus, W., Arshad, S. H., Dabelea, D., Sorensen, T. I. A., Laivuori, H., Räikkönen, K., Felix, J. F., London, S. J., Hivert, M-F., Gaunt, T. R., Lawlor, D. A. & Relton, C. L., Aug 2019, In : Hypertension. 74, 2, p. 375-383 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Psychiat Genomics Consortium, Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O'Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C. & 14 others, Jones, M. J., Lin, D. T. S., MacIsaac, J. L., Kobor, M. S., Koen, N., Zar, H. J., Koenen, K. C., Dalvie, S., Stein, D. J., Kondofersky, I., Mueller, N. S., Theis, F. J., Raikkonen, K. & Binder, E. B., 11 Jun 2019, In : Nature Communications. 10, 18 p., 2548.

Research output: Contribution to journalArticleScientificpeer-review

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Longitudinal changes in plasma hemopexin and alpha-1-microglobulin concentrations in women with and without clinical risk factors for pre-eclampsia

Murtoniemi, K., Kalapotharakos, G., Vahlberg, T., Räikkonen, K., Kajantie, E., Hämäläinen, E., Åkerström, B., Villa, P. M., Hansson, S. R. & Laivuori, H., 16 Dec 2019, In : PLoS One. 14, 12, e0226520.

Research output: Contribution to journalArticleScientificpeer-review

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Maternal antenatal daytime sleepiness and child neuropsychiatric and neurocognitive development

Lahti-Pulkkinen, M., Mina, T. H., Riha, R. L., Raikkonen, K., Pesonen, A. K., Drake, A. J., Denison, F. C. & Reynolds, R. M., Sep 2019, In : Psychological Medicine. 49, 12, p. 2081-2090 10 p., 003329171800291.

Research output: Contribution to journalArticleScientificpeer-review

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Maternal early pregnancy body mass index and diurnal salivary cortisol in young adult offspring

Kumpulainen, S. M., Heinonen, K., Kaseva, N., Andersson, S., Lano, A., Reynolds, R. M., Wolke, D., Kajantie, E., Eriksson, J. G. & Räikkönen, K., Jun 2019, In : Psychoneuroendocrinology. 104, p. 89-99 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Kupers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C., Allard, C., Just, A. C., Bakulski, K. M., Holloway, J. W. & 107 others, Everson, T. M., Xu, C-J., Huang, R-C., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M-R., Bergstrom, A., Ortqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Haberg, S. E., Sorensen, T. I. A., Taylor, J. A., Räikkönen, K., Yang, I., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hämäläinen, E., Routledge, M. N., Boomsma, D., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melen, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M-F., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Smith, G. D., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 23 Apr 2019, In : Nature Communications. 10, 11 p., 1893.

Research output: Contribution to journalArticleScientificpeer-review

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Musculoskeletal pain in adults born preterm: Evidence from two birth cohort studies

Evensen, K. A. I., Tikanmäki, M., Heinonen, K., Matinolli, H-M., Sipola-Leppänen, M., Lano, A., Wolke, D., Vääräsmäki, M., Eriksson, J. G., Andersson, S., Järvelin, M-R., Hovi, P., Räikkönen, K. & Kajantie, E., Mar 2019, In : European Journal of Pain. 23, 3, p. 461-471 11 p.

Research output: Contribution to journalArticleScientificpeer-review

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

Evangelou, E., Gao, H., Chu, C., Ntritsos, G., Blakeley, P., Butts, A. R., Pazoki, R., Suzuki, H., Koskeridis, F., Yiorkas, A. M., Karaman, I., Elliott, J., Luo, Q., Aeschbacher, S., Bartz, T. M., Baumeister, S. E., Braund, P. S., Brown, M. R., Brody, J. A., Clarke, T-K. & 78 others, Dimou, N., Faul, J. D., Homuth, G., Jackson, A. U., Kentistou, K. A., Joshi, P. K., Lemaitre, R. N., Lind, P. A., Lyytikainen, L-P., Mangino, M., Milaneschi, Y., Nelson, C. P., Nolte, I. M., Perälä, M-M., Polasek, O., Porteous, D., Ratliff, S. M., Smith, J. A., Stancakova, A., Teumer, A., Tuominen, S., Theriault, S., Vangipurapu, J., Whitfield, J. B., Wood, A., Yao, J., Yu, B., Zhao, W., Arking, D. E., Auvinen, J., Liu, C., Männikkö, M., Risch, L., Rotter, J., Snieder, H., Veijola, J., Blakemore, A., Boehnke, M., Campbell, H., Conen, D., Eriksson, J. G., Grabe, H. J., Guo, X., van der Harst, P., Hartman, C. A., Hayward, C., Heath, A. C., Jarvelin, M-R., Kähönen, M., Kardia, S. L. R., Kuhne, M., Kuusisto, J., Laakso, M., Lahti, J., Lehtimäki, T., McIntosh, A. M., Mohlke, K. L., Morrison, A. C., Martin, N. G., Oldehinkel, A. J., Penninx, B. W. J. H., Psaty, B. M., Raitakari, O. T., Rudan, I., Samani, N. J., Scott, L. J., Spector, T. D., Verweij, N., Weir, D. R., Wilson, J. F., Levy, D., Tzoulaki, I., Bell, J. D., Matthews, P. M., Rothenfluh, A., Desrivieres, S., Schumann, G. & Elliott, P., Sep 2019, In : Nature Human Behaviour. 3, 9, p. 950-961 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Plasma Heme Scavengers Alpha-l-Microglobulin and Hemopexin as Biomarkers in High-Risk Pregnancies

Kalapotharakos, G., Murtoniemi, K., Åkerström, B., Hämäläinen, E., Kajantie, E., Räikkönen, K., Villa, P., Laivuori, H. & Hansson, S. R., 4 Apr 2019, In : Frontiers in Physiology. 10, 7 p., 300.

Research output: Contribution to journalArticleScientificpeer-review

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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

Lam, M., Hill, W. D., Trampush, J. W., Yu, J., Knowles, E., Davies, G., Stahl, E., Huckins, L., Liewald, D. C., Djurovic, S., Melle, I., Sundet, K., Christoforou, A., Reinvang, I., DeRosse, P., Lundervold, A. J., Steen, V. M., Espeseth, T., Räikkönen, K., Widen, E. & 48 others, Palotie, A., Eriksson, J. G., Giegling, I., Konte, B., Hartmann, A. M., Roussos, P., Giakoumaki, S., Burdick, K. E., Payton, A., Ollier, W., Chiba-Falek, O., Attix, D. K., Need, A. C., Cirulli, E. T., Voineskos, A. N., Stefanis, N. C., Avramopoulos, D., Hatzimanolis, A., Arking, D. E., Smyrnis, N., Bilder, R. M., Freimer, N. A., Cannon, T. D., London, E., Poldrack, R. A., Sabb, F. W., Congdon, E., Conley, E. D., Scult, M. A., Dickinson, D., Straub, R. E., Donohoe, G., Morris, D., Corvin, A., Gill, M., Hariri, A. R., Weinberger, D. R., Pendleton, N., Bitsios, P., Rujescu, D., Lahti, J., Le Hellard, S., Keller, M. C., Andreassen, O. A., Deary, I. J., Glahn, D. C., Malhotra, A. K. & Lencz, T., Aug 2019, In : American Journal of Human Genetics. 105, 2, p. 334-350 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths

Halldorsdottir, T., Piechaczek, C., de Matos, A. P. S., Czamara, D., Pehl, V., Wagenbuechler, P., Feldmann, L., Quickenstedt-Reinhardt, P., Allgaier, A-K., Freisleder, F. J., Greimel, E., Kvist, T., Lahti, J., Raikkonen, K., Rex-Haffner, M., Arnarson, E. O., Craighead, W. E., Schulte-Koerne, G. & Binder, E. B., Aug 2019, In : American Journal of Psychiatry. 176, 8, p. 615-625 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Predictors of surgical site skin infection and clinical outcome at caesarean section in the very severely obese: A retrospective cohort study

Dias, M., Dick, A., Reynolds, R. M., Lahti-Pulkkinen, M. & Denison, F. C., 27 Jun 2019, In : PLoS One. 14, 6, 15 p., 0216157.

Research output: Contribution to journalArticleScientificpeer-review

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Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy

Van Den Bergh, B., van den Heuvel, M. I., Lahti-Pulkkinen, M., Braeken, M., de Rooij, S. R., Entringer, S., Hover, D., Roseboom, T., King, S. & Schwab, M., 2019, (Accepted/In press) In : Neuroscience & Biobehavioral Reviews.

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REM sleep fragmentation associated with depressive symptoms and genetic risk for depression in a community-based sample of adolescents

Pesonen, A-K., Gradisar, M., Kuula, L., Short, M., Merikanto, I., Tark, R., Raikkonen, K. & Lahti, J., 15 Feb 2019, In : Journal of Affective Disorders. 245, p. 757-763 7 p.

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Rintaruokinnan suotuisat vaikutukset ulottuvat läpi elämänkaaren

Rantalainen, V. & Räikkönen, K., 2019, In : Terveydenhoitaja. 52, 1, p. 34-35 2 p.

Research output: Contribution to journalArticleProfessional