Publications 2005 2019

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2019

3D-printability of aqueous poly(ethylene oxide) gels

Viidik, L., Seera, D., Antikainen, O., Kogermann, K., Heinämäki, J. & Laidmäe, I., 23 Aug 2019, In : European Polymer Journal.

Research output: Contribution to journalArticleScientificpeer-review

Acetalated Dextran Nanoparticles Loaded into an Injectable Alginate Cryogel for Combined Chemotherapy and Cancer Vaccination

Bauleth-Ramos, T., Ting-Yu Shih, T-Y. S., Shahbazi, M-A., Najibi, A. J., Mao, A. S., Liu, D., Granja, P., Santos, H. A., Sarmento, B. & Mooney, D. J., 28 Aug 2019, In : Advanced Functional Materials. 29, 35, p. 1903686 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Antimicrobial Colloidal Silver-Lignin Particles via Ion- and Solvent Exchange

Sakari Lintinen, K., Luiro, S., Figueiredo, P., Sakarinen, E., Mousavi, Z., Seitsonen, J., N. S. Rivière, G., Mattinen, U., Niemelä, M., Tammela, P., Österberg, M., Johansson, L-S., Bobacka, J., Santos, H. A. & A. Kostiainen, M., 16 Aug 2019, In : ACS Sustainable Chemistry & Engineering. 7, 18, p. 15297-15303 7 p.

Research output: Contribution to journalArticleScientificpeer-review

A Virus-Mimicking pH-Responsive Acetalated Dextran-Based Membrane-Active Polymeric Nanoparticle for Intracellular Delivery of Antitumor Therapeutics

Wannasarit, S., Wang, S., Figueiredo, P., Trujillo Olvera, C. X., Eburnea, F., Simón-Gracia, L., Correia, A., Ding, Y., Teesalu, T., Liu, D., Wiwattanapatapee, R., Santos, H. A. & Li, W., 20 Sep 2019, (Accepted/In press) In : Advanced Functional Materials.

Research output: Contribution to journalArticleScientificpeer-review

Cardiovascular and sedation reversal effects of intramuscular administration of atipamezole in dogs treated with medetomidine hydrochloride with or without the peripheral α2-adrenoceptor antagonist vatinoxan hydrochloride

Turunen, H., Raekallio, M., Honkavaara, J., Restitutti, F., Kallio-Kujala, I. J., Adam, M., Nevanperä, K., Scheinin, M., Männikkö, S., Hautajarvi, H., Larenza Menzies, M. P. & Vainio, O., Oct 2019, (Accepted/In press) In : American Journal of Veterinary Research. 80

Research output: Contribution to journalArticleScientificpeer-review

CDNF Protein Therapy in Parkinson’s Disease

Huttunen, H. J. & Saarma, M., 4 Apr 2019, In : Cell Transplantation. 28, 4, p. 349-366 18 p.

Research output: Contribution to journalArticleScientificpeer-review

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Cost-effectiveness of abatacept, tocilizumab and TNF-inhibitors compared with rituximab as second-line biologic drug in rheumatoid arthritis

Huoponen, S., Aaltonen, K. J., Viikinkoski, J., Rutanen, J., Relas, H., Taimen, K., Puolakka, K., Nordström, D. & Blom, M., 24 Jul 2019, In : PLoS One. 14, 7, p. e0220142

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Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

Lilius, T., Blomqvist, K., Hauglund, N., Liu, G., Stæger, F. F., Bærentzen, S., Du, T., Ahlström, F., Backman, J., Kalso, E., Rauhala, P. & Nedergaard, M., 5 May 2019, In : Journal of Controlled Release.

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Diagnosis and management of individuals with Fetal Valproate Spectrum Disorder; a consensus statement from the European Reference Network for Congenital Malformations and Intellectual Disability

Clayton-Smith, J., Bromley, R., Dean, J., Journel, H., Odent, S., Wood, A., Williams, J., Cuthbert, V., Hackett, L., Aslam, N., Malm, H., James, G., Westbom, L., Day, R., Ladusans, E., Jackson, A., Bruce, I., Walker, R., Sidhu, S., Dyer, C. & 5 othersAshworth, J., Hindley, D., Diaz, G. A., Rawson, M. & Turnpenny, P., 19 Jul 2019, In : Orphanet journal of rare diseases. 14, 1

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Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease

Albert, K., Voutilainen, M. H., Domanskyi, A., Piepponen, T. P., Ahola, S., Tuominen, R. K., Richie, C., Harvey, B. K. & Airavaara, M., Mar 2019, In : Journal of Neuroscience Research. 97, 3, p. 346-361 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of nanofibrillated cellulose hydrogels on adipose tissue extract and hepatocellular carcinoma cell spheroids in freeze-drying

Auvinen, V-V., Merivaara, A., Kiiskinen, J., Paukkonen, H., Laurén, P., Hakkarainen, T., Koivuniemi, R., Sarkanen, R., Ylikomi, T., Laaksonen, T. & Yliperttula, M., 15 Sep 2019, In : Cryobiology.

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Entsyymien merkitys hermorappeumataudeissa

Kursula, P. & Myöhänen, T., 2019, In : Duodecim. 135, 8, p. 745-752

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Identification and characterization of a novel subtype of Tula virus in Microtus arvalis obscurus voles sampled from Xinjiang, China

Chen, J-T., Qin, J., Li, K., Xu, Q-Y., Wang, X-P., Plyusnin, A., Hou, W. & Zhang, Y-Z., 22 Aug 2019, In : Infection, genetics and evolution.

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Improved synthesis of [18F] fallypride and characterization of a Huntington’s disease mouse model, zQ175DN KI, using longitudinal PET imaging of D2/D3 receptors

Huhtala, T., Poutiainen, P., Rytkönen, J., Lehtimäki, K., Parkkari, T., Kasanen, I., Airaksinen, A. J., Koivula, T., Sweeney, P., Kontkanen, O., Wityak, J., Dominiquez, C. & Park, L. C., 5 Aug 2019, In : EJNMMI Radiopharmacy and Chemistry. 4, 1

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Levels of glial cell line-derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in parkinson's disease

Virachit, S., Mathews, K. J., Cottam, V., Werry, E., Galli, E., Rappou, E., Lindholm, P., Saarma, M., Halliday, G. M., Shannon Weickert, C. & Double, K. L., 29 Apr 2019, In : Brain Pathology.

Research output: Contribution to journalArticleScientificpeer-review

Metallization of Organically Modified Ceramics for Microfluidic Electrochemical Assays

Bonabi, A., Tähkä, S., Ollikainen, E., Jokinen, V. & Sikanen, T., 12 Sep 2019, In : Micromachines. 10, 9

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Multi-parametric single cell evaluation defines distinct drug responses in healthy hematological cells that are retained in corresponding malignant cell types

Majumder, M. M., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Kopperud, R., Bazou, D., Andersson, E., Parsons, A., Tang, J., Kallioniemi, O., Mustjoki, S., O'Gorman, P., Wennerberg, K., Porkka, K., Gjertsen, B. T. & Heckman, C. A., 22 Aug 2019, In : Haematologica. p. haematol.2019.217414

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Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer

Tang, J., Gautam, P., Gupta, A., He, L., Timonen, S., Akimov, Y., Wang, W., Szwajda, A., Jaiswal, A., Turei, D., Yadav, B., Kankainen, M., Saarela, J., Saez-Rodriguez, J., Wennerberg, K. & Aittokallio, T., 2019, In : npj Systems Biology and Applications. 5, 1

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Neuronal activation stimulates cytomegalovirus promoter-driven transgene expression

Bäck, S., Dossat, A., Parkkinen, I., Koivula, P., Airavaara, M., Richie, C. T., Chen, Y-H., Wang, Y. & Harvey, B. K., 2019, In : Molecular therapy-Methods & clinical development.

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Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site

Lopes, A., Feola, S., Ligot, S., Fusciello, M., Vandermeulen, G., Préat, V. & Cerullo, V., 10 Jul 2019, In : Journal for Immunotherapy of Cancer. 7, 1

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Pain interference type and level guide the assessment process in chronic pain: Categorizing pain patients entering tertiary pain treatment with the Brief Pain Inventory

Miettinen, T., Kautiainen, H., Mäntyselkä, P., Linton, S. J. & Kalso, E., 20 Aug 2019, In : PLoS One. 14, 8, p. e0221437

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Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia

Kuusanmäki, H., Leppä, A-M., Pölönen, P., Kontro, M., Dufva, O., Deb, D., Yadav, B., Bruck, O., Kumar, A., Everaus, H., Gjertsen, B. T., Heinäniemi, M., Porkka, K., Mustjoki, S. & Heckman, C., 11 Jul 2019, In : Haematologica.

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Raajan vetäytymisheijaste kivun mittauksessa

Pertovaara, A. Y., 2019, In : Kipuviesti : Suomen kivuntutkimusyhdistyksen jäsenlehti.. 1, p. 54 1 p.

Research output: Contribution to journalArticleProfessional

Research in Specialization Studies in Industrial Pharmacy benefits pharmaceutical industry

Juppo, A. & Siven, M., 2019, In : Dosis. 35, 1, p. 90-96

Research output: Contribution to journalArticleScientificpeer-review

Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents

Fedorowicz, J., Sączewski, J., Konopacka, A., Waleron, K., Lejnowski, D., Ciura, K., Tomašič, T., Skok, Ž., Savijoki, K., Morawska, M., Gilbert-Girard, S. & Fallarero, A., 2019, In : European Journal of Medicinal Chemistry. 179

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Trends in the receipt of medicines information among Finnish adults in 1999–2014: a nationwide repeated cross-sectional survey

Mononen, N., Airaksinen, M., Hämeen-Anttila, K., Helakorpi, S. & Pohjanoksa-Mäntylä, M., 2019, In : BMJ Open.

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Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy

Yong, T., Zhang, X., Bie, N., Zhang, H., Zhang, X., Li, F., Hakeem, A., Hu, J., Gan, L., Santos, H. A. & Yang, X., 23 Aug 2019, In : Nature Communications. 10, 1, p. 3838 16 p.

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2018

Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation

Richardson, D., Itkonen, J., Nievas, J., Urtti, A. & Casteleijn, M. G., 10 Aug 2018, In : Scientific Reports. 8, 1, 11 p., 11967 .

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Accurate Calibration in Multi-Material 3D Bioprinting for Tissue Engineering

Sodupe-Ortega, E., Sanz-Garcia, A., Pernia-Espinoza, A. & Escobedo-Lucea, C., 10 Aug 2018, In : Materials. 11, 8, 19 p., 1402.

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A deep convolutional neural network approach for astrocyte detection

Suleymanova, I., Balassa, T., Tripathi, S., Molnar, C., Saarma, M., Sidorova, Y. & Horvath, P., 27 Aug 2018, In : Scientific Reports. 8, 7 p., 12878.

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A microfluidic oxygen sink to create a targeted cellular hypoxic microenvironment under ambient atmospheric conditions

Barmaki, S., Jokinen, V., Obermaier, D., Blokhina, D., Korhonen, M., Ras, R. H. A., Vuola, J., Franssila, S. & Kankuri, E., Jun 2018, In : Acta Biomaterialia. 73, p. 167-179 13 p.

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A Multiplexed Screening Assay to Evaluate Chemotherapy-Induced Myelosuppression Using Healthy Peripheral Blood and Bone Marrow

Javarappa, K. K., Tsallos, D. & Heckman, C. A., Aug 2018, In : SLAS discovery . 23, 7, p. 687-696 10 p.

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Antitumor-specific T-cell responses induced by oncolytic adenovirus ONCOS-102 (AdV5/3-D24-GM-CSF) in peritoneal mesothelioma mouse model

Kuryk, L., Moller, A-S. W., Garofalo, M., Cerullo, V., Pesonen, S., Alemany, R. & Jaderberg, M., Oct 2018, In : Journal of Medical Virology. 90, 10, p. 1669-1673 5 p.

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Attenuated dopaminergic neurodegeneration and motor dysfunction in hemiparkinsonian mice lacking the α5 nicotinic acetylcholine receptor subunit

Leino, S., Koski, S. K., Hänninen, R., Tapanainen, T., Rannanpää, S. & Salminen, O., 28 Jun 2018, In : Neuropharmacology. 138, p. 371-380 9 p.

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Bentsodiatsepiinien pitkäaikaiskäyttö on vähentynyt

Kurko, T., Saastamoinen, L., Tuulio-Henriksson, A., Taiminen, T., Tiihonen, J., Airaksinen, M. & Hietala, J., 2018, In : Suomen lääkärilehti. 73, 20, p. 1292-1297 6 p.

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Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements

Parkkila, P., Elderdfi, M., Bunker, A. & Viitala, T., 10 Jul 2018, In : Langmuir. 34, 27, p. 8081-8091 11 p.

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Can Practical Nurses Identify Older Home Care Clients at Risk of Drug-Related Problems-Geriatricians' Appraisal of Their Risk Screenings: A Pilot Study

Dimitrow, M., Puustinen, J., Viikari, P., Puumalainen, E., Vahlberg, T., Airaksinen, M. S. A. & Kivelä, S-L., Jun 2018, In : Journal of Pharmacy Technology. 34, 3, p. 99-108 10 p.

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Cytochrome P450 in Pharmacogenetics: An Update

Tornio, A. & Backman, J. T., 2018, In : Advances in Pharmacology. 83, p. 3-32 30 p.

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Development of an AmpliSeq (TM) Panel for Next-Generation Sequencing of a Set of Genetic Predictors of Persisting Pain

Kringel, D., Kaunisto, M. A., Lippmann, C., Kalso, E. & Lötsch, J., 19 Sep 2018, In : Frontiers in Pharmacology. 9, 22 p., 1008.

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