Projects per year
Organization profile
Organisation Profile
ILS is an international doctoral program providing structured training in life sciences areas requiring multidisciplinary skills and capability engage in multiprofessional cooperation. The Life Science areas that are strong in Finland include Genetics, Cell and Developmental Biology, Cancer Research, Neuroscience and Virology. These areas share a strong component of multidisciplinary approaches bridging research in basic biosciences, computational sciences and medicine. The research groups affiliated in ILS represent the highest quality life science research in Helsinki. Their research interests cover nearly all aspects of modern life sciences ranging from molecular medicine and developmental biology to biophysics and systems biology.
Research and doctoral training in ILS includes the following fields of science:
- Proteomics and Metabolomics
- Genetics and Genomics
- Developmental Biology and Physiology
- Cell and Molecular Biology
- Bioinformatics and Systems Biology
- Biochemistry, Biophysics and Structural Biology
International and National Collaboration
Publications and projects within past five years.
Profiles
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Lauri Aaltonen, Professor
- Department of Medical and Clinical Genetics - Professor
- Doctoral Programme in Biomedicine - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
Person: UH, U4 Research and teaching staff
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Maria Aatonen, Laboratory Coordinator
- Faculty of Biological and Environmental Sciences - Laboratory Coordinator
- Extracellular Vesicles
- Doctoral Programme in Integrative Life Science
Person: Doctoral student, M5 Teaching and research support staff, UH
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Mervi Aavikko
- Medicum - Title of Docent
- Institute for Molecular Medicine Finland - Senior Researcher
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH
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Kaia Achim
- Molecular and Integrative Biosciences Research Programme - Academy Research Fellow
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
Person: U3 Research and teaching staff
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Tero Ahola
- Department of Microbiology - University Lecturer
- Helsinki One Health (HOH)
- RNA virus replication and antivirals
- Doctoral Programme in Drug Research - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Microbiology and Biotechnology - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH, Teaching and research personnel
Equipment
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Director of Histology Core Facility
Nicolas Di-Poi (Manager)
Doctoral Programme BrainFacility/equipment: Core Facility
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Instruct-HiLIFE CryoEM core facility
Sarah Butcher (Manager), Ausra Domanska (Operator), Pasi Laurinmäki (Operator) & Benita Löflund (Operator)
Institute of BiotechnologyFacility/equipment: Core Facility
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INSTRUCT HILIFE protein crystallography platform
Tommi Kajander (Manager)
Institute of BiotechnologyFacility/equipment: Core Facility
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Molecular Interactions - Biacore T100
Minna Poranen (Manager) & Maria Aatonen (Operator)
BiosciencesFacility/equipment: Equipment
Projects
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DECIDER: DECIDER (Clinical Decision via Integrating Multiple Data Levels to Overcome Chemotherapy Resistance in High-Grade Serous Ovarian Cancer)
Korpisaari (ex. Tiilikka), P., Hautaniemi, S. & Mansnérus, J.
01/02/2021 → 31/01/2026
Project: Research project
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Translation and neoplasia – the multifaceted role of post-transcriptional transfer RNA modification
Gregorova, P., Heinonen, M. K. & Sarin, P.
Sigrid Juseliuksen Säätiö, Sigrid Juselius Foundation
01/05/2020 → 30/04/2022
Project: Research project
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GOOD: Improved gut heath by wood-derived gums (Jane and Aatos Erkko Foundation)
Kynkäänniemi, E. K., Lahtinen, M., Pajari, A. & Mikkonen, K. S.
01/01/2020 → 31/12/2022
Project: Research project
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ProteRNA: Enhanced Production of Heterologous Proteins Following Translational Fine-Tuning by Optimized Post-Transcriptional RNA Modification
Sarin, P., Qasim, M. S., Abendroth, U., Pedor, J. K. & Kalaniemi, S. M.
01/09/2019 → 31/08/2024
Project: Research project
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Leg4Life: Legumes for sustainable food system and healthy life
Pajari, A., Piironen, V., Vanhatalo, A., Simojoki, A., Jouppila, K., Kariluoto, S., Päivärinta, E., Konttinen, H., Hyytiäinen, K., Lombardini (former Lombardini-Riipinen), C., Lamminen, M., Alakukku, L., Chamlagain, B., Coda, R., Ertbjerg, P., Edelmann, M., Halmemies-Beauchet-Filleau, A., Itkonen, S., Katina, K., Knaapila, A., Kokkonen, T., Kuoppala, K., Lampi, A., Mäkelä, P., Nurmi, V., Ramos-Diaz, J. M., Salonen, A., Sandell, M., Sihvonen, M., Sontag-Strohm, T., Stoddard, F., Tenkanen, M. & Varmanen, P.
01/06/2019 → 31/08/2022
Project: Research project
Publications
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A comparative analysis of parechovirus structure within the Picornaviridae
Domanska, A., Guryanov, S. & Butcher, S., 7 Jan 2021, (Submitted) In : Open biology.Research output: Contribution to journal › Review Article › peer-review
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Aminopeptidase Expression in Multiple Myeloma Associates with Disease Progression and Sensitivity to Melflufen
Miettinen, J., Kumari, R., Traustadottir, G. A., Huppunen, M-E. A., Sergeev, P., Majumder, MM., Schepsky, A., Gudjonsson, T., Lievonen, J., Bazou, D., Dowling, P., O'Gorman, P., Slipicevic, A., Anttila, P., Silvennoinen, R., Nupponen, N., Lehmann, F. & Heckman, C., Apr 2021, In : Cancers. 13, 7, 21 p., 1527.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Analysis of phloem trajectory links tissue maturation to cell specialization.
Roszak, P., Heo, J., Blob, B., Toyokura, K., De Luis Balaguer, M. A., Lau, W., Hamey, F. K., Cirrone, J., Wang, X., Ursache, R., Tavares, H., Verstaen, K., Wendrich, J., Melnyk, C. W., Shasha, D., Ahnert, S., Saeys, Y., De Rybel, B., Heidstra, R., Scheres, B. & 5 others, , 19 Jan 2021, (Unpublished) In : bioRxiv : the preprint server for biology .Research output: Contribution to journal › Article › Scientific › peer-review
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Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
Talwelkar, S., 2021, (Submitted) In : bioRxiv.Research output: Contribution to journal › Article › Scientific › peer-review
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Genetic variants for morningness in relation to habitual sleep-wake behavior and diurnal preference in a population-based sample of 17,243 adults
Merikanto, I., Kantojärvi, K., Partonen, T., Pesonen, A-K. & Paunio, T., 30 Jan 2021, In : Sleep Medicine. 80, p. 322-332Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
Activities
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Development of data integration methods in cell biology
Maciej Lalowski (Member of thesis committee / follow-up group)
1 Apr 2021 → 31 Dec 2025Activity: Examination types › Member of doctoral thesis committee / follow-up group
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Anatomical Sciences Education (Journal)
Juha Laakkonen (Reviewer)
2021 → …Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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Pre-examiner of doctoral thesis
Katarina Pelin (Pre-examiner)
11 Jan 2021 → 22 Jan 2021Activity: Examination types › Pre-examiner of doctoral thesis
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Journal of Veterinary Medical Education (Journal)
Juha Laakkonen (Reviewer)
2021 → …Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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International Journal of Molecular Sciences (Journal)
Kristiina Himanen (Reviewer)
14 Jan 2021Activity: Publication peer-review and editorial work types › Peer review of manuscripts
Prizes
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1st prize from Orion Pharma Competition on¨"Making more efficient medicines"
D. A. Garcia, Susana (Recipient), 2017
Prize: Prizes and awards
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Datasets
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SynergyFinder
Tang, J. (Creator), University of Helsinki, 2017
DOI: doi: 10.1093/bioinformatics/btx162, http://synergyfinder.org
Dataset
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DrugTargetCommons
Tang, J. (Creator), University of Helsinki, 2018
DOI: 10.1016/j.chembiol.2017.11.009, http://drugtargetcommons.org
Dataset
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DrugComb
Tang, J. (Creator), University of Helsinki, 2019
DOI: 10.1093/nar/gkz337, http://drugcomb.org
Dataset
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Metabolomic signature of the maternal microbiota in the fetus
Niku, M. (Creator), Pessa-Morikawa, T. (Creator), Husso, A. (Creator) & Iivanainen, A. (Creator), EUDAT, 2021
DOI: http://doi.org/10.23728/b2share.4be0ea9f87b84a06be960d6a1c4b0b42
Dataset
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Press / Media
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Vegaaninen ruokavalio altistaa päiväkoti-ikäisen vitamiinipuutoksille, kertoo tutkimus
Liisa Korkalo & Anu Suomalainen Wartiovaara
22/01/2021
1 Media contribution
Press/Media: Press / Media
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University of Helsinki researchers developed a sequence analysis pipeline for virus discovery
Ilja Pljusnin, Ravi Kant, Teemu Smura, Tarja Sironen & Olli Vapalahti
03/12/2020
1 item of Media coverage
Press/Media: Press / Media
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Haastattelu: Helsingin Sanomat. Sairauksia saatetaan alkaa hoitaa vitamiineilla.
01/06/2020
1 item of Media coverage
Press/Media: Press / Media
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50 000 hyttystä kerännyt tutkija löysi Suomesta uuden lajin, jonka tunnistaminen oli tuskaa – ”Olen käsitellyt paljon hyttysten sukuelimiä”
24/06/2019
1 item of Media coverage
Press/Media: Press / Media