Projects per year
Organization profile
ILS is an international doctoral program providing structured training in life sciences areas requiring multidisciplinary skills and capability engage in multiprofessional cooperation. The Life Science areas that are strong in Finland include Genetics, Cell and Developmental Biology, Cancer Research, Neuroscience and Virology. These areas share a strong component of multidisciplinary approaches bridging research in basic biosciences, computational sciences and medicine. The research groups affiliated in ILS represent the highest quality life science research in Helsinki. Their research interests cover nearly all aspects of modern life sciences ranging from molecular medicine and developmental biology to biophysics and systems biology.
Research and doctoral training in ILS includes the following fields of science:
- Proteomics and Metabolomics
- Genetics and Genomics
- Developmental Biology and Physiology
- Cell and Molecular Biology
- Bioinformatics and Systems Biology
- Biochemistry, Biophysics and Structural Biology
International and National Collaboration
Publications and projects within past five years.
Profiles
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Lauri Aaltonen, Professor
- Department of Medical and Clinical Genetics - Professor
- ATG - Applied Tumor Genomics - Academy Professor
- Doctoral Programme in Biomedicine - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
Person: UH , U4 Research and teaching staff
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Mervi Aavikko
- Medicum - Title of Docent
- Institute for Molecular Medicine Finland - Senior Researcher
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH
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Kaia Achim
- Molecular and Integrative Biosciences Research Programme - Academy Research Fellow
- Doctoral Programme Brain & Mind - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
Person: U3 Research and teaching staff
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Tero Ahola
- Department of Microbiology - Senior University Lecturer
- Helsinki One Health (HOH)
- RNA virus replication and antivirals
- Doctoral Programme in Drug Research - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Microbiology and Biotechnology - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH , Teaching and research personnel
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Laura Ahtiainen
- Faculty Common Matters (Faculty of Biology and Environmental Sciences) - Title of Docent
- Doctoral Programme in Biomedicine - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
Person: UH
Equipment
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Director of Histology Core Facility
Nicolas Di-Poi (Manager)
Doctoral Programme Brain & MindFacility/equipment: Core Facility
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Instruct-HiLIFE CryoEM core facility
Sarah Butcher (Manager), Ausra Domanska (Operator), Pasi Laurinmäki (Operator) & Behnam Lak (Operator)
Institute of BiotechnologyFacility/equipment: Core Facility
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Instruct-HILIFE protein crystallography platform
Tommi Kajander (Manager)
Institute of BiotechnologyFacility/equipment: Core Facility
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Molecular Interactions - Biacore T100
Minna Poranen (Manager) & Maria Aatonen (Operator)
Facility/equipment: Equipment
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Effect of organic environmental chemicals on endocrine and metabolic diseases in dogs and cats
Spillmann, T., Björkman, S. & Pohjanvirta, R.
01/08/2022 → …
Project: Research project
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Metabolic and oxidative stress biomarkers in sows with postpartum dysgalactia syndrome and subsequent endometritis
Björkman, S., Malik, M., Kaiser, M. O. & Ceron, J. J.
01/08/2022 → …
Project: Research project
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CHEMODI: Modulation of post-transcriptional transfer RNA modification as an enhancer of chemotherapeutic agents
Sarin, P., Gregorova, P., Halme, M. M., Gregorova, P. & Heinonen, M. K.
01/05/2022 → 30/04/2024
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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ASTROS: ASTROS: How meristems guide plant reproductive development?
01/01/2022 → 31/12/2025
Project: Research project
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Ducks as models for assessIng endocrine DISRUPTing chemicals in the aquatic environment - Incubation behavior of Common Goldeneye and Common Eider under endocrine-disrupting chemicals and environmental pressure
Shahrbabaki, S. V., Björkman, S. & Arzel, C.
01/01/2022 → …
Project: Research project
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Abolishment of morphology-based taxa and change to binomial species names: 2022 taxonomy update of the ICTV bacterial viruses subcommittee
Turner, D., Shkoporov, A. N., Lood, C., Millard, A. D., Dutilh, B. E., Alfenas-Zerbini, P., van Zyl, L. J., Aziz, R. K., Oksanen, H. M., Poranen, M., Kropinski, A. M., Barylski, J., Brister, J. R., Chanisvili, N., Edwards, R., Enault, F., Gillis, A., Knezevic, P., Krupovic, M., Kurtboke, I., & 16 others, 2023, In: Archives of Virology. 168, 74Research output: Contribution to journal › Review Article › peer-review
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Aging disrupts MANF-mediated immune modulation during skeletal muscle regeneration
Sousa, N. S., Bras, M. F., Antunes, I. B., Lindholm, P., Neves, J. & Sousa-Victor, P., 23 Mar 2023, In: Nature Aging. 31 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Altered acylcarnitine metabolism and inflexible mitochondrial fuel utilization characterize the loss of neonatal myocardial regeneration capacity.
Kankuri, E., Finckenberg, P., Leinonen, J., Tarkia, M., Björk, S., Purhonen, J., Kallijärvi, J., Kankainen, M., Soliymani, R., Lalowski, M. & Mervaala, E., 3 Apr 2023, (E-pub ahead of print) In: Experimental & Molecular Medicine. 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
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A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy
Eteläinen, T., Silva, M. C., Uhari-Väänänen, J., De Lorenzo, F., Jäntti, M., Cui, H., Chavero-Pieres, M., Kilpeläinen, T., Mechtler, C., Svarcbahs, R., Seppälä, E., Savinainen, J., Puris, E., Fricker, G., Gynther, M., Julku, U., Huttunen, H., Haggarty, S. & Myöhänen, T., 12 Apr 2023, In: Science translational medicine. 15, 691, 10.1126/scitranslmed.abq2915.Research output: Contribution to journal › Article › Scientific › peer-review
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Azulene as a biphenyl mimetic in orexin/hypocretin receptor agonists
Leino, T., Turku, A., Urvas, L., Adhikari, K., Oksanen, J., Steynen, Y., Yli-Kauhaluoma, J., Xhaard, H., Kukkonen, J. & Wallén, E. A. A., 6 Jun 2023, In: Bioorganic & Medicinal Chemistry. 88-89, 9 p., 117325.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
Activities
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FinnGen: Origin and Progress
Aarno Palotie (Speaker)
9 Feb 2023Activity: Talk or presentation types › Oral presentation
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FinnGen: a large, nationwide biobank project
Aarno Palotie (Speaker)
23 Feb 2023Activity: Talk or presentation types › Invited talk
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Anatomical Sciences Education (Journal)
Juha Laakkonen (Reviewer)
2023 → …Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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NeuroInsight (External organisation)
Aarno Palotie (Board member)
14 Feb 2023Activity: Membership types › Membership or other role in review committee
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FinnGen projekti
Aarno Palotie (Speaker)
31 Jan 2023Activity: Talk or presentation types › Oral presentation
Prizes
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1st prize from Orion Pharma Competition on¨"Making more efficient medicines"
D. A. Garcia, Susana (Recipient), 2017
Prize: Prizes and awards
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Datasets
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Metabolomic signature of the maternal microbiota in the fetus
Niku, M. (Creator), Pessa-Morikawa, T. (Creator), Husso, A. (Creator) & Iivanainen, A. (Creator), EUDAT, 2021
DOI: http://doi.org/10.23728/b2share.4be0ea9f87b84a06be960d6a1c4b0b42
Dataset
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LAM publication figure dataset
Viitanen, A. I. (Creator), Fairdata.fi, 20 Jun 2021
DOI: https://doi.org/10.23729/fac30a2e-1de5-45d6-879e-f67129bc822d
Dataset
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SynergyFinder Plus (SynergyFinder+)
Tang, J. (Creator), University of Helsinki, 2022
DOI: 10.1016/j.gpb.2022.01.004, http://www.synergyfinder.org and one more link, https://tangsoftwarelab.shinyapps.io/synergyfinder/ (show fewer)
Dataset
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DrugComb
Tang, J. (Creator), University of Helsinki, 2019
DOI: 10.1093/nar/gkz337, http://drugcomb.org
Dataset
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DrugTargetCommons
Tang, J. (Creator), University of Helsinki, 2018
DOI: 10.1016/j.chembiol.2017.11.009, http://drugtargetcommons.org
Dataset
Press/Media
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Podcast haastattelu: Migreeni ja perinnöllisyys
15/03/2023
1 Media contribution
Press/Media: Press / Media
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