Projects per year
Organisation profile
Organisation Profile
Our goal is to assess the contribution of genome and epigenome to obesity and other complex diseases and traits using study designs suitable for twin and population-based cohorts. We measure within-pair and intra-individual epigenetic and phenotypic differences and stability longitudinally, and aim at developing epigenetic biomarkers for disease risk prediction and potential intervention targets for complex diseases.
International and National Collaboration
Profiles
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Sailalitha Bollepalli, Postdoctoral Researcher
- Institute for Molecular Medicine Finland - Bioinformatician
- Epigenetics of Complex Diseases and Traits
Person: U1 Research and teaching staff, M5 Teaching and research support staff
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Miina Ollikainen
- Institute for Molecular Medicine Finland - Senior Researcher
- Faculty Common Matters (Faculty of Biology and Environmental Sciences) - Title of Docent
- Epigenetics of Complex Diseases and Traits
- Doctoral Programme in Population Health - Supervisor for doctoral programme
Person: U3 Research and teaching staff
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Mitochondrial biogenesis, epigenetics & obesity
Ollikainen, M., Lundgren, S. N., Pietiläinen, K. & Pirinen, E.
01/09/2019 → …
Project: Research project
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Applying novel computational methods and multiple data types to derive new hypotheses into the molecular mechanisms behind obesity
Kibble, M. M., Ollikainen, M., Bollepalli, S., Khan, S. A., Ammad-ud-din, M. & Pietiläinen, K.
01/01/2017 → …
Project: Research project
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Substance use epigenetics
Ollikainen, M., Loukola, A., Gupta, R., Bollepalli, S., Kaprio, J., Korhonen, T., Cazaly, E., Salvatore, J. E., Stephenson, M. & Anders, S.
01/01/2017 → …
Project: Research project
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Using epigenetic alterations in monozygotic twins to predict the development of metabolic syndrome
Kibble, M. M., Ollikainen, M., Bollepalli, S. & Fu, Y.
01/01/2017 → …
Project: Research project
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Epigenetic pathways to obesity
Bollepalli, S., Kibble, M. M., Muniandy, M., Lundgren, S. N. & Ollikainen, M.
01/09/2016 → 31/08/2021
Project: Research project
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TWINGEN: Protocol for an observational clinical biobank recall and biomarker cohort study to identify Finnish individuals with high risk of Alzheimer's disease
Vuoksimaa, E., Saari, T. T., Aaltonen, A., Aaltonen, S., Herukka, S-K., Iso-Markku, P., Kokkola, T., Kyttälä, A., Kärkkäinen, S., Liedes, H., Ollikainen, M., Palviainen, T., Ruotsalainen, I., Toivola, A., Urjansson, M., Vasankari, T., Vähä-Ypyä, H., Forsberg, M. M., Hiltunen, M., Jalanko, A., & 11 others , 12 Jun 2024, In: BMJ Open. 14, 6, 14 p., e081947.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Trans-ancestry epigenome-wide association meta-analysis of DNA methylation with lifetime cannabis use
Fang, F., Quach, B., Lawrence, K. G., van Dongen, J., Marks, J. A., Lundgren, S., Lin, M., Odintsova, V. V., Costeira, R., Xu, Z., Zhou, L., Mandal, M., Xia, Y., Vink, J. M., Bierut, L. J., Ollikainen, M., Taylor, J. A., Bell, J. T., Kaprio, J., Boomsma, D. I., & 4 others , Nov 2023, In: Molecular Psychiatry. 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
TWINGEN - protocol for an observational clinical biobank recall and biomarker study to identify individuals with high risk of Alzheimer’s disease
FinnGen, Palotie, A., Kaprio, J., Runz, H. & Julkunen, V., 2023, (Submitted) In: medRxiv. p. 2023-11Research output: Contribution to journal › Article › Scientific
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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Million Veterans Program, Global Lipids Genetics Consortium, Ramdas, S., Judd, J., Graham, S. E., Surakka, I., Havulinna, A. S., Weir, D. R., Ruotsalainen, S. E., Loukola, A., Bollepalli, S., Kaprio, J., Koistinen, H. A., Kivimäki, M., Ripatti, S., Widén, E., Tuomilehto, J., Jousilahti, P., Sun, Y. V., Ikeda, D. D., & 1 others , 4 Aug 2022, In: American Journal of Human Genetics. 109, 8, p. 1366-1387 23 p.Research output: Contribution to journal › Article › Scientific › peer-review
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A saturated map of common genetic variants associated with human height
23andMe Res Team, VA Million Vet Program, DiscovEHR DiscovEHR MyCode Communi, eEMERGE Elect Med Records Genomics, LifeLines Cohort Study, PRACTICAL Consortium, Understanding Soc Sci Grp, Yengo, L., Vedantam, S., Marouli, E., Bollepalli, S., Havulinna, A. S., Ruotsalainen, S. E., Kaprio, J., Kivimäki, M., Koistinen, H. A., Ripatti, S., Tuomi, T., Tuomilehto, J. & Widen, E., 27 Oct 2022, In: Nature. 610, 7933, p. 704-+ 35 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Activities
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The 50th Behavior Genetics Association Meeting
Sailalitha Bollepalli (Attendee)
26 Jun 2020Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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BioC 2020: Where Software and Biology Connect
Sailalitha Bollepalli (Attendee)
27 Jul 2020 → 31 Jul 2020Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Data Science Summer School
Sailalitha Bollepalli (Poster Presentation)
24 Jun 2019 → 28 Jun 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Centre for Molecular Medicine Norway (NCMM) University of Oslo
Sailalitha Bollepalli (Visiting researcher)
14 Jan 2019 → 26 Jan 2019Activity: Visiting an external institution types › Academic visit to other institution
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Data Science for A Better Life: Bayer Workshop
Sailalitha Bollepalli (Poster Presentation)
21 Nov 2019 → 23 Nov 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars