Projects per year
Organisation profile
Our goal is to assess the contribution of genome and epigenome to obesity and other complex diseases and traits using study designs suitable for twin and population-based cohorts. We measure within-pair and intra-individual epigenetic and phenotypic differences and stability longitudinally, and aim at developing epigenetic biomarkers for disease risk prediction and potential intervention targets for complex diseases.
International and National Collaboration
Publications and projects within past five years.
Profiles
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Sailalitha Bollepalli, Postdoctoral Researcher
- Institute for Molecular Medicine Finland - Bioinformatician
- Epigenetics of Complex Diseases and Traits
Person: U1 Research and teaching staff, M5 Teaching and research support staff
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Miina Ollikainen
- Institute for Molecular Medicine Finland - Senior Researcher
- Faculty Common Matters (Faculty of Biology and Environmental Sciences) - Title of Docent
- Epigenetics of Complex Diseases and Traits
- Doctoral Programme in Population Health - Supervisor for doctoral programme
Person: U3 Research and teaching staff
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Mitochondrial biogenesis, epigenetics & obesity
Ollikainen, M., Lundgren, S. N., Pietiläinen, K. & Pirinen, E.
01/09/2019 → …
Project: Research project
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Substance use epigenetics
Ollikainen, M., Loukola, A., Gupta, R., Bollepalli, S., Kaprio, J., Korhonen, T., Cazaly, E., Salvatore, J. E., Stephenson, M. & Anders, S.
01/01/2017 → …
Project: Research project
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Using epigenetic alterations in monozygotic twins to predict the development of metabolic syndrome
Kibble, M. M., Ollikainen, M., Bollepalli, S. & Fu, Y.
01/01/2017 → …
Project: Research project
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Applying novel computational methods and multiple data types to derive new hypotheses into the molecular mechanisms behind obesity
Kibble, M. M., Ollikainen, M., Bollepalli, S., Khan, S. A., Ammad-ud-din, M. & Pietiläinen, K.
01/01/2017 → …
Project: Research project
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Epigenetic pathways to obesity
Bollepalli, S., Kibble, M. M., Muniandy, M., Lundgren, S. N. & Ollikainen, M.
01/09/2016 → 31/08/2021
Project: Research project
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Trans-ancestry epigenome-wide association meta-analysis of DNA methylation with lifetime cannabis use
Fang, F., Quach, B., Lawrence, K. G., van Dongen, J., Marks, J. A., Lundgren, S., Lin, M., Odintsova, V. V., Costeira, R., Xu, Z., Zhou, L., Mandal, M., Xia, Y., Vink, J. M., Bierut, L. J., Ollikainen, M., Taylor, J. A., Bell, J. T., Kaprio, J., Boomsma, D. I., & 4 others, Nov 2023, In: Molecular Psychiatry. 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
TWINGEN - protocol for an observational clinical biobank recall and biomarker study to identify individuals with high risk of Alzheimer’s disease
FinnGen, Palotie, A., Kaprio, J., Runz, H. & Julkunen, V., 2023, (E-pub ahead of print) In: medRxiv. p. 2023-11Research output: Contribution to journal › Article › Scientific › peer-review
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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Million Veterans Program, Global Lipids Genetics Consortium, Ramdas, S., Judd, J., Graham, S. E., Surakka, I., Havulinna, A. S., Weir, D. R., Ruotsalainen, S. E., Loukola, A., Bollepalli, S., Kaprio, J., Koistinen, H. A., Kivimäki, M., Ripatti, S., Widén, E., Tuomilehto, J., Jousilahti, P., Sun, Y. V., Ikeda, D. D., & 1 others, 4 Aug 2022, In: American Journal of Human Genetics. 109, 8, p. 1366-1387 23 p.Research output: Contribution to journal › Article › Scientific › peer-review
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A saturated map of common genetic variants associated with human height
23andMe Res Team, VA Million Vet Program, DiscovEHR DiscovEHR MyCode Communi, eEMERGE Elect Med Records Genomics, LifeLines Cohort Study, PRACTICAL Consortium, Understanding Soc Sci Grp, Yengo, L., Vedantam, S., Marouli, E., Bollepalli, S., Havulinna, A. S., Ruotsalainen, S. E., Kaprio, J., Kivimäki, M., Koistinen, H. A., Ripatti, S., Tuomi, T., Tuomilehto, J. & Widen, E., 27 Oct 2022, In: Nature. 610, 7933, p. 704-+ 35 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
BMI is positively associated with accelerated epigenetic aging in twin pairs discordant for body mass index
Lundgren, S., Kuitunen, S., Pietiläinen, K. H., Hurme, M., Kähönen, M., Männistö, S., Perola, M., Lehtimäki, T., Raitakari, O., Kaprio, J. & Ollikainen, M., Oct 2022, In: Journal of Internal Medicine. 292, 4, p. 627-640 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Activities
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The 50th Behavior Genetics Association Meeting
Sailalitha Bollepalli (Attendee)
26 Jun 2020Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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BioC 2020: Where Software and Biology Connect
Sailalitha Bollepalli (Attendee)
27 Jul 2020 → 31 Jul 2020Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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PRACE: Practical Deep Learning
Sailalitha Bollepalli (Attendee)
13 Feb 2019 → 14 Feb 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Centre for Molecular Medicine Norway (NCMM) University of Oslo
Sailalitha Bollepalli (Visiting researcher)
14 Jan 2019 → 26 Jan 2019Activity: Visiting an external institution types › Academic visit to other institution
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Epigenetic Analyses
Sailalitha Bollepalli (Speaker)
25 Apr 2019Activity: Talk or presentation types › Invited talk