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2020

Bitopic and Peripheral Membrane Proteins as Drug Targets: Broader Biophysical Insight from Biomembrane Simulations that Transcends the "Lock and Key'' Paradigm

Bunker, A., 7 Feb 2020, In : Biophysical Journal. 118, 3, p. 160A-160A 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

MicroRNA-193a family as potential clinical biomarker and therapeutic agent in advanced Melanoma

Carpi, S., Polini, B., Ylösmäki, L., Ylösmäki, E., Cerullo, V., Romanini, A. & Nieri, P., 11 Feb 2020, In : Journal of Translational Medicine. 18, Supplement 1, 1 p., 25.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Regioselective Prenylation of Peptide Termini during the Biosynthesis of the Natural Product Muscoride

Mattila, A., Andsten, R-M., Jumppanen, M., Assante, M., Jokela, J., Wahlsten, M., Mikula, K. M., Gugger, M., Koskela, H., Sivonen, K., Yli-Kauhaluoma, J., Iwai, H. & Fewer, D. P., Jan 2020, In : Marine Drugs. 18, 1, 1 p., 40.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2019

A potent partial agonist of PKC orients in membranes like the biological activator diacylglycerol

Lautala, S., Koivuniemi, A., Kulig, W., Rog, T., Talman, V., Tuominen, R. & Bunker, A., Jul 2019, In : European Biophysics Journal. 48, p. S122-S122 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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Association between the arrested decline in cardiovascular disease and health and social-care costs: a modelling study

Collins, B., Bandosz, P., Guzman-Castillo, M., Pearson-Stuttard, J., Stoye, G., McCauley, J., Ahmadi-Abhari, S., Shipley, M. J., Araghi, M., Capewell, S., French, E., Brunner, E. J. & O'Flaherty, M., Nov 2019, In : Lancet. 394, Supplement 2, p. 33-33 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Asthma is still a risk factor for mortality in Sweden and Norway ̣— the Nordic EpiLung Study

Backman, H., Bhatta, L., Hedman, L., Brumpton, B., Vähätalo, I., Lassman-Klee, P. G., Nwaru, B. I., Mai, X-M., Vikjord, S. A., Lindberg, A., Lundbäck, B., Rönmark, E. & Langhammer, A., 2019, In : European Respiratory Journal. 54, PA2778.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Azulene-based compounds targeting orexin receptors

Leino, T., Turku, A., Yli-Kauhaluoma, J., Kukkonen, J., Xhaard, H. & Wallen, E., 31 Mar 2019, In : Abstracts of papers of the American Chemical Society . 257, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Brain metabolome during anesthesia - similarities and differences between post-ictal state

Kohtala, S., Kärkkäinen, O. & Rantamäki, T., 2019, In : European Neuropsychopharmacology. 29, p. S645-S646 2 p.

Research output: Contribution to journalMeeting AbstractResearch

Brain region-dependent variation in myelin-related gene expression and myelin thickness in chronic psychosocial stress

Laine, M. A., Trontti, K., Misiewicz, Z., Sokolowska, E., Kulesskaya, N., Heikkinen, A., Saarnio, S., Balcells, I., Ameslon, P., Greco, D., Mattila, P., Ellonen, P., Paulin, L., Auvinen, P., Jokitalo, E. & Hovatta, I., Jul 2019, In : Glia. 67, p. E450-E451 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Characterization Of Focal And Generalized Epilepsy Polygenic Burden In 630,603 Individuals

Epi-Twenty-Five Consortium, Nov 2019, In : Epilepsia. 60, p. 27-28 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling

Murumagi, A., Ungureanu, D., Khan, S., Hirasawa, A., Arjama, M., Valimaki, K., Mikkonen, P., Niininen, W., Kumar, A., Eldfors, S., Pellinen, T., Pietiainen, V., Magi, A., Koivisto-Korander, R., Tapper, J., Loukovaara, M., Aittokallio, T., Butzow, R. & Kallioniemi, O., Jul 2019, In : Cancer Research. 79, 13, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Combination effects of essential oils with antimicrobials

Stalnacke, M., Mgbeahuruike, E. & Holm, Y., Dec 2019, In : Planta Medica. 85, 18, p. 1523-1523 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Conductive 3D printed structures based on nanocellulose for electro-responsiveness and controlled drug release

Ajdary, R., Ezazi, N. Z., Huan, S., Santos, H. & Rojas, O., 31 Mar 2019, In : Abstracts of papers of the American Chemical Society . 257, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Developmental and cognitive profile of children with intestinal failure

Gunnar, R., Kanerva, K., Salmi, S., Hayrinen, T., Haataja, L., Pakarinen, M. & Merras-Salmio, L., Jul 2019, In : Transplantation. 103, p. S29-S30 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Differences of FENO in adult general populations of Nordic regions

Lassmann-Klee, P., Brumpton, B., Henriksen, A. H., Larsson, M., Sundblad, B-M., Põlluste, J., Lindqvist, A., Hedman, L., Backman, H., Rönmark, E., Langhammer, A., Piirilä, P. & Sovijärvi, A. R. A., 28 Sep 2019, In : European Respiratory Journal. 54, Suppl. 63, p. PA5064

Research output: Contribution to journalMeeting AbstractResearch

Doxorubicin-Induced Cardiotoxicity and Novel GATA4-Targeted Compounds

Karhu, T., Kinnunen, S., Talman, V. & Ruskoaho, H., 2 Aug 2019, In : Circulation Research. 125, A781, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Drug screening and molecular profiling identifies INKA1 as a predictive biomarker for sensitivity to MAPK inhibition-antimitotic combination treatment in pancreatic ductal adenocarcinoma

Gautam, P., Vaha-Koskela, M., Tomlinson, M., Cox, A. D., Der, C. J., Aittokallio, T. & Wennerberg, K., Dec 2019, In : Molecular Cancer Therapeutics. 18, 12 suppl., 2 p., A137.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Effect of Donor Simvastatin Treatment on Gene Expression Profiles in Human Cardiac Allografts during Ischemia-Reperfusion Injury

Krebs, R., Kankainen, M., Holmström, E., Dhaygude, K., Lukac, J., Ojala, T., Mattila, P., Nykänen, A. & Lemström, K., Apr 2019, In : Journal of Heart and Lung Transplantation. 38, 4, Supplement, p. S75-S76 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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EVALUATION OF SAFE MEDICATION USE AMONG HOME CARE AND NURSING FACILITIES OLDER PATIENTS IN ESTONIA AND FINLAND

Bobrova, V., Baburina, U., Heinamaki, J., Honkanen, O., Desselle, S., Airaksinen, M. & Volmer, D., Dec 2019, In : Research in Social and Administrative Pharmacy. 15, 12, p. E47-E47 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Genetic risk information (APOE) as a lifestyle change motivator in Finland - Description of the participant population

Tringham, M., Leskinen, H., Karjalainen, H., Iso-Touru, T., Hietaranta-Luoma, H., Rokka, S., Marnila, P., Pihlava, J., Hurme, T., Pietila, A., Puolijoki, H., Akerman, K., Tanner, L., Sandell, M., Vahakangas, K., Hopia, A. & Tahvonen, R., Oct 2019, In : European Journal of Human Genetics. 27, p. 1796-1797 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

GENETICS OF HUMAN PLASMA LIPIDOME AND ITS LINK TO DISEASES SUSCEPTIBILITY

SK Serv, T FinnGen Project, Tabassum, R., Rämö, J. T., Ripatti, P., Koskela, J. T., Kurki, M., Karjalainen, J., Palta, P., Hassan, S., Nunez-Fontarnau, J., Kiiskinen, T. T. J., Soderlund, S., Matikainen, N., Laivuori, H., Havulinna, A. S., Salomaa, V., Pirinen, M., Jauhiainen, M., Daly, M. J. & 3 others, Palotie, A., Taskinen, M. R. & Ripatti, S., Aug 2019, In : Atherosclerosis. 287, p. E14-E15 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

GENETICS OF VACCINATION RELATED NARCOLEPSY

Ollila, H., Wennerstrom, A., Partinen, M., Mignot, E., Saarela, J., Saavalainen, P., Vaarala, O., Tienari, P. & Perola, M., 2019, In : European Neuropsychopharmacology. 29, p. S994-S994 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Genome wide association studies of semen cryoability in cocks (Gallus gallus)

Kudinov, A., Dementeva, N., Silyukova, Y., Pleshanov, N., Stanishevskaya, O., Mitrofanova, O. & Nikitkina, E., Sep 2019, In : Reproduction in Domestic Animals. 54, p. 74-74 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Identification of C. elegans lipid lowering constituents form chaga by correlation of H-1 NMR spectra with phenotypic screening

Kirchweger, B., Kapp, K., Grienke, U., Lehner, T., Zwirchmayr, J., Tahir, A. & Rollinger, J. M., Dec 2019, In : Planta Medica. 85, 18, p. 1395-1395 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Induced and primed defence responses of Fragaria vesca against grey mold

Badmi, R., Zhang, Y., Tengs, T., Brurberg, M. B., Krokene, P., Fossdal, C. G., Hytonen, T. & Thorstensen, T., Oct 2019, In : Molecular Plant - Microbe Interactions. 32, 10, p. S1.9 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Injury Severity and Extracranial Injuries Are Associated with Delayed Return to Work in Mild Traumatic Brain Injury Patients

Huovinen, A., Isokuortti, H., Marinkovic, I., Vanni, S. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 128-129 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

In situ detection of DNA double strand breaks by immunofluorescent gamma-H2AX staining in mice exposed to multiwalled carbon nanotubes

Aimonen, K., Huumonen, K., Savukoski, S., Lindberg, H., Schoonenberg, A., Valimaki, K., Libertini, S., Wolff, H., Catalan, J. & Norppa, H., 15 Oct 2019, In : Toxicology Letters. 314, p. S122-S122 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Intracranial Traumatic Lesions Delay Return to Work in Mild Traumatic Injury Patients

Huovinen, A., Marinkovic, I., Isokuortti, H., Korvenoja, A., Vanni, S. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 130-131 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Label-Free Proteomics Approach Characterizes Plasma Protein Signature of Donor Brain Death

Lukac, J., Saraswat, M., Holmström, E., Dhaygude, K., Joenväärä, S., Krebs, R., Nykänen, A., Renkonen, R. & Lemström, K., Apr 2019, In : Journal of Heart and Lung Transplantation. 38, 4, Supplement, p. S159 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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L-LEUCINE COATED INHALABLE TEICOPLANIN POWDERS PRODUCED BY AEROSOL FLOW REACTOR METHOD

Ugur, N., Bimbo, L. M., Saris, P., Vartiainen, V., Hirvonen, J., Kauppinen, E. I. & Raula, J., 1 Jun 2019, In : Journal of Aerosol Medicine and Pulmonary Drug Delivery. 32, 3, p. A18-A19 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

LP(A)-DEPENDENT INFLAMMASOME ACTIVATION AS A DRIVER OF ITS ATHEROGENICITY

Oorni, K., Lorey, M. B., Borelli, M., Tigistu-Sahle, F., Ruuth, M., Aikas, L., Kakela, R., Boffa, M. B. & Koschinsky, M. L., Aug 2019, In : Atherosclerosis. 287, p. E282-E282 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Multivariate GWAS of inflammatory markers reveals novel disease associations

Ruotsalainen, S. E., Partanen, J., Surakka, I., Pirinen, M., Salomaa, V., Salmi, M., Jalkanen, S., Daly, M. J., Ripatti, S. & Koskela, J., 10 Oct 2019, In : European Journal of Human Genetics. 27, 11, p. 1156-1157 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

NEEDS FOR, AND EXPECTATIONS OF, A POSTGRADUATE PHARMACY PROGRAM

Niittynen, I., Linden-Lahti, C. & Laaksonen, R., Dec 2019, In : Research in Social and Administrative Pharmacy. 15, 12, p. E51-E51 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Notebook: Customizable web forms for recording observations

Raitio, O. A., Juslén, A., Sirkiä, P., Lehikoinen, A., Tähtinen, M., Piirainen, E. & Riihikoski, V-M., 20 Aug 2019, In : Biodiversity Information Science and Standards. 3, 3 p., e39150.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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Pluripotent stem cells differentiation towards definitive endoderm

Bogacheva, M., Kanninen, L. & Lou, Y-R., 15 Oct 2019, In : Toxicology Letters. 314, p. S186-S187 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

POLYGENIC HYPERLIPIDEMIA INCREASES CORONARY ARTERY DISEASE RISK IN THE UK BIOBANK

Ripatti, P., Ramo, J. T., Soderlund, S., Surakka, I., Havulinna, A. S., Widen, E., Palta, P., Freimer, N. B., Salomaa, V., Pirinen, M., Palotie, A., Taskinen, M. R. & Ripatti, S., Aug 2019, In : Atherosclerosis. 287, p. E92-E92 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Pre-hospital thrombolysis of high-risk pulmonary embolism-patient characteristics, management and outcome

Harjola, J., Holmström, P., Kuisma, M. & Harjola, V-P., May 2019, In : European Journal of Heart Failure. 21, p. 131-132 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Prognostic impact of angiographic results in cardiogenic shock

CardShock, Javanainen, T., Lassus, J., Nieminen, M., Tolppanen, H., Jäntti, T., Kataja, A., Hongisto, M., Tarvasmaki, T., Harjola, V-P. & Jurkko, R., May 2019, In : European Journal of Heart Failure. 21, p. 450-450 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Psychiatric Disorders and Return to Work after Mild Traumatic Brain Injury

Marinkovic, I., Isokuortti, H., Huovinen, A., Korvenoja, A., Vataja, R. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 153-153 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Synergistic effect of combined administration of an oncolytic adenovirus and Bifidobacterium spp. supplements in a mouse model of melanoma

Tripodi, L., Leggiero, E., D'Argenio, V., Granata, I., Capasso, C., Passariello, M., D'Agostino, A., Guarracino, M. R., De Lorenzo, C., Cerullo, V. & Pastore, L., 1 Nov 2019, In : Human Gene Therapy. 30, 11, p. A30-A31 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The catalytic mechanism of MB-COMT: new drug design paradigm?

Bunker, A., Rog, T., Magarkar, A., Parkkila, P., Lajunen, T., Mobarak, E., Cramariuc, O., Licari, G. & Vauthey, E., Jul 2019, In : European Biophysics Journal. 48, p. S63-S63 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

THE ECONOMIC IMPACT OF SERIOUS FLUOROQUINOLONE-RELATED ADVERSE EVENTS

Saarukka, L., Backman, J. T. & Blom, M., Nov 2019, In : Value in Health. 22, p. S600-S600 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The EuroDEM-study: does arrival mode affect ED management and outcome of acute heart failure patient?

Harjola, P., Martin, P-L., Tarvasmaki, T., Harjola, V-P. & Laribi, S., May 2019, In : European Journal of Heart Failure. 21, p. 260-260 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The Role of Protein Kinase C Isoforms in Cardiomyocyte Hypertrophy

Pohjolainen, L., Solanki, R., Ruskoaho, H. & Talman, V., 2 Aug 2019, In : Circulation Research. 125, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The shared mutation and neoantigen landscape of MMR-deficient colorectal cancers suggests immunoediting during tumor evolution

Kloor, M., Ballhausen, A., Przybilla, M., Jendrusch, M., Pfaffendorf, E., Draxlbauer, M., Seidler, F., Krausert, S., Ahadova, A., Kalteis, S., Heid, D., Gebert, J., Bonsack, M., Schott, S., Blaeker, H., Seppälä, T. T., Mecklin, J-P., Ten Broeke, S., Nielsen, M., Krzykalla, J. & 3 others, Benner, A., Riemer, A. & Doeberitz, M. V. K., Jul 2019, In : Cancer Research. 79, 13 s, 3 p., 571.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Ticagrelor decreases concentrations of prothrombotic extracellular vesicles compared to clopidogrel

Gasecka, A., Nieuwland, R., Budnik, M., Dignat-George, F., Eyileten, C., Harrison, P., Kaplon-Cieslicka, A., Lacroix, R., Opolski, G., Van der Pol, E., Postula, M., Leroyer, A., Siljander, P., Sturk, A. & Filipiak, K., Oct 2019, In : European Heart Journal. 40, p. 75-75 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Weaker Nonverbal Skills at 5 Years of Age Predict Need for Long-Term Educational Support in Very Preterm Children

Lind, A., Nyman, A., Lehtonen, L. & Haataja, L., Sep 2019, In : Perception. 48, p. 174-174 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2018

(242) - Donor Plasma VEGF as a Biomarker for Early Graft Failure After Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Holmström, E., Tuuminen, R., Krebs, R., Rouvinen, E., Nykänen, A. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S103

Research output: Contribution to journalMeeting AbstractResearchpeer-review

(245) - Proinflammatory Cytokines as Biomarkers for Severe Primary Graft Dysfunction After Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Holmström, E., Tuuminen, R., Syrjälä, S., Krebs, R., Rouvinen, E., Nykänen, A. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S104

Research output: Contribution to journalMeeting AbstractResearchpeer-review