Publications 1966 2019

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2019

Brain metabolome during anesthesia - similarities and differences between post-ictal state

Kohtala, S., Kärkkäinen, O. & Rantamäki, T., 2019, In : European Neuropsychopharmacology. 29, p. S645-S646 2 p.

Research output: Contribution to journalMeeting AbstractResearch

2018

(242) - Donor Plasma VEGF as a Biomarker for Early Graft Failure After Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Holmström, E., Tuuminen, R., Krebs, R., Rouvinen, E., Nykänen, A. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S103

Research output: Contribution to journalMeeting AbstractResearchpeer-review

(245) - Proinflammatory Cytokines as Biomarkers for Severe Primary Graft Dysfunction After Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Holmström, E., Tuuminen, R., Syrjälä, S., Krebs, R., Rouvinen, E., Nykänen, A. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S104

Research output: Contribution to journalMeeting AbstractResearchpeer-review

(348) - Worldwide Experience of Adult Patients with Small Body Size Supported by a Continuous-Flow Left Ventricular Assist Device - An IMACS Analysis: ISHLT 38th Annual Meeting and Scientific Sessions

Lee, S., Xie, R., Lemstrom, K., Dickinson, M. G., Boeve, T., Leacche, M., Cowger, J., de By, T. & Kirklin, J. K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S145 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Cardiovascular autonomic function after simultaneous pancreas-kidney and kidney-alone transplantation in patients with diabetes

Paajanen, H., Bordino, M., Sandelin, A., Ekstrand, A., Lempinen, M., Forsblom, C., Bernardi, L. & Groop, P-H., 2018, (Accepted/In press) In : Diabetes Care. 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Clinical and Genetic Characterization of Canine Vitreous Degeneration

Kaukonen, M. & Lohi, H., Jul 2018, In : Investigative Ophthalmology & Visual Science. 59, 9, 2 p., 6042.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Combined Targeting of BET Family Proteins and BCL2 Is Synergistic in Acute Myeloid Leukemia Cells Overexpressing S100A8 and S100A9

Karjalainen, R., Liu, M., Kumar, A., Parsons, A., He, L., Malani, D. R., Kontro, M., Porkka, K. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

COSTS AND HEALTH SERVICE USE ASSOCIATED WITH FLUOROQUINOLONE-RELATED TENDON INJURIES

Saarukka, L., Backman, J. T. & Blom, M., Oct 2018, In : Value in Health. 21, p. S293-S293 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Donor Simvastatin Treatment Alters Protein Expression in the Recipient after Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Lukac, J., Holmström, E., Joenväärä, S., Saraswat, M., Krebs, R., Tohmola, T., Nykänen, A., Renkonen, R. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, p. S169-S170 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Efficient fine-mapping to identify causal genetic variants and quantify their contribution to complex phenotypes

Benner, C., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., Oct 2018, In : Genetic Epidemiology. 42, 7, p. 688-689 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Eltrombopag Promotes Megakaryocyte Survival and Signaling in the Presence of Specific Cytotoxic Agents

Javarappa, K. K., Tsallos, D., Zagidullin, B., Saad, J., Tang, J., Ramos, P. M., Pallaud, C. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Enantiospecific Pharmacogenomics of Fluvastatin

Hirvensalo, P., Tornio, A., Neuvonen, M., Kiander, W., Kidron, H., Paile-Hyvärinen, M., Tapaninen, T., Backman, J. & Niemi, M., May 2018, In : Basic & Clinical Pharmacology & Toxicology. 123, p. 7-7 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Epidemiology, genetic models and epigenetics of insomnia

Paunio, T., Sep 2018, In : Journal of Sleep Research. 27, 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Genome-Scale CRISPR Screens Identify Essential Genes for Sensitivity to Natural Killer Cells in Hematological Malignancies

Dufva, O., Klievink, J., Saeed, K., Kankainen, M., Ilander, M., Hannunen, T., Lagstrom, S., Ellonen, P., Lee, D. A. & Mustjoki, S., 29 Nov 2018, In : Blood. 132, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Intrinsically Disordered Proteins PH-Induced Structural Transitions in Overcrowded Milieu

Fonin, A. V., Asiya, S. K., Gagarskaia, I. A., Kostyleva, E. I., Karasev, M. M., Povarova, O. I., Uversky, V. N., Kuznetsova, I. M. & Turoverov, K. K., 2 Feb 2018, In : Biophysical Journal. 114, 3/Supplement 1, p. 591A-591A 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Late Breaking Abstract - Conversion of FENO from different flows to the standard flow.

Lassmann-Klee, P., Lehtimaki, L., Lindholm, T., Malmberg, P., Sovijarvi, A. & Piirila, P., 15 Sep 2018, In : European Respiratory Journal. 52, Suppl 62, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Melatonin receptor type 1A gene linked to intolerance to shift work and Alzheimer's disease in old age

Sulkava, S., Muggalla, P., Sulkava, R., Ollila, H. M., Peuralinna, T., Myllykangas, L., Helisalmi, S., Soininen, H., Polvikoski, T., Hiltunen, M., Tienari, P. J., Huttunen, H. J. & Paunio, T., Sep 2018, In : Journal of Sleep Research. 27, Supplement 1, 1 p., P007.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Multi-Parametric Single Cell Profiling Defines Distinct Drug Responses in Healthy Hematological Cell Lineages That Are Retained in Corresponding Malignant Cell Types

Majumder, MM., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Bazou, D., Andersson, E. I., Parsons, A., Tang, J., Kallioniemi, O-P., Mustjoki, S. M., O'Gorman, P., Wennerberg, J. K., Porkka, K. V. K., Gjertsen, B-T. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Novel mutations in fibronectin associated with metaphyseal fractures - Expanding the phenotype of patients with a subtype of spondylomethaphyseal dysplasia with "corner fractures"

Alm, J. J., Costantini, A., Valta, H., Baratang, N. V., Yap, P., Bertola, D., Yamamoto, G., Kim, C. A., Chen, J., Wierenga, K. J., Fanning, E. A., Escobar, L., Mcwalter, K., Mclaughlin, H., Willaert, R., Begtrup, A., Reinhardt, D. P., Makitie, O. & Campeau, P. M., Nov 2018, In : Journal of Bone and Mineral Research. 33, p. 417-417 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Oncolytic Adenoviruses Encapsulated into the Extracellular Vesicles as Carriers for Cancer Drug Delivery

Garofalo, M., Saari, H., Somersalo, P., Crescenti, D., Kuryk, L., Aksela, L., Capasso, C., Madetoja, M., Koskinen, K., Makitie, A., Jalasvuori, M., Cerullo, V., Ciana, P. & Yliperttula, M., May 2018, In : Molecular therapy. 26, 5, p. 203-203 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Role of CDNF in SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis

Voutilainen, M. H., De Lorenzo, F., Montonen, E., Tuominen, R. K., Lindholm, D., Sendtner, M. & Saarma, M., Apr 2018, In : Cell Transplantation. 27, 4, p. 717-718 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Somatic Mutations in CD8+T Cells in Patients with Chronic Immune Thrombocytopenia Are Associated with Increased Clonality and Cytotoxic Phenotype of CD8+T Cells

Rajala, H., Savola, P., Lundgren, S., Eldfors, S., Kelkka, T., Ebeling, F. & Mustjoki, S., 29 Nov 2018, In : Blood. 132, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

What's in a shopping basket? Alcohol and grocery purchases among Finnish loyalty-card holders

Uusitalo, P. L., Erkkola, M., Lintonen, T., Rahkonen, O. & Nevalainen, J., Nov 2018, In : European Journal of Public Health. 28, suppl_4, p. 140-140 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2017

Changes in risky alcohol use and sickness absence

Ervasti, J., Kivimäki, M., Pentti, J., Halonen, J. I., Vahtera, J. & Virtanen, M., Nov 2017, In : European Journal of Public Health. 27, suppl. 3, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Characterization of Immunological Profiles with Clinical Significance in Patients with Classical Hodgkin Lymphoma

Karihtala, K., Leivonen, S-K., Karjalainen-Lindsberg, M-L. & Leppa, S., 7 Dec 2017, In : Blood. 130, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CHILDHOOD ADVERSITY, ADULT SOCIOECONOMIC STATUS AND RISK OF WORK DISABILITY - A PROSPECTIVE COHORT STUDY

Kivimaki, M., Vahtera, J., Pentti, J., Virtanen, M., Ervasti, J. & Lallukka, T., Sep 2017, In : Journal of Epidemiology & Community Health. 71, Suppl. 1, p. A61-A61 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CHRONIC MYELOID LEUKEMIA PATIENTS WERE NOT DIFFERENT IN MOLECULAR RELAPSE AFTER STOPPING IMATINIB IN MR4 WHETHER RESIDUAL DISEASE WAS DETECTED OR NOT - WHEN ADJUSTING FOR NUMBER OF CONTROL TRANSCRIPTS

Pfirrmann, M., Mahon, F-X., Guilhot, J., Richter, J., Almeida, A., Janssen, J. J., Mayer, J., Koskenvesa, P., Panayiotidis, P., Olsson-Stromberg, U., Berger, M. G., Diamond, J., Ehrencrona, H., Kairisto, V., Polakova, K. M., Mueller, M. C., Mustjoki, S., Hochhaus, A., Saussele, S. & Hjorth-Hansen, H., 26 Jun 2017, In : Haematologica. 102, p. 153-153 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CLINICAL AND IMMUNOLOGICAL EFFECTS OF NILOTINIB IN COMBINATION WITH PEGYLATED INTERFERON-A2B IN PATIENTS WITH SUBOPTIMAL MOLECULAR RESPONSE ON IMATINIB (NORDDUTCHCML009)

Geelen, I., Olsson-Stromberg, U., Mustjoki, S., Richter, J., Blijlevens, N., Smit, W., Gjertsen, B., Gedde-Dahl, T., Markevarn, B., Koppes, M., Westerweel, P., Janssen, J. & Hjorth-Hansen, H., 26 Jun 2017, In : Haematologica. 102, p. 435-435 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Copanlisib (COP) in patients with relapsed or refractory indolent B-cell lymphoma: primary results of the pivotal Chronos-1 study

Dreyling, M., Santoro, A., Mollica, L., Leppa, S., Follows, G. A., Lenz, G., Kim, W. S., Nagler, A., Panayiotidis, P., Demeter, J., Ozcan, M., Kosinova, M., Bouabdallah, K., Morschhauser, F., Stevens, D. A., Trevarthen, D., Giurescu, M., Kupit, L., Childs, B. H. & Zinzani, P. L., Sep 2017, In : Oncology research and treatment. 40, p. 12-12 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Copanlisib in patients with relapsed or refractory follicular lymphoma.

Dreyling, M. H., Santoro, A., Leppa, S., Demeter, J., Follows, G., Lenz, G., Kim, W. S., Mollica, L., Nagler, A., Diong, C. P., Provencio, M., Stevens, D. A., Trevarthen, D., Magagnoli, M., Cupit, L., Yin, S., Hiemeyer, F., -Vargas, J. E. G., Childs, B. H. & Zinzani, P. L., 20 May 2017, In : Journal of Clinical Oncology. 35, 5 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Copanlisib treatment in patients with relapsed or refractory indolent B-cell lymphoma: Subgroup analyses from the CHRONOS-1 study

Provencio Pulla, M., Santoro, A., Mollica, L., Leppa, S., Follows, G., Lenz, G., Kim, W. S., Nagler, A., Panayiotidis, P., Demeter, J., Ozcan, M., Kosinova, M., Bouabdallah, K., Morschhauser, F., Ishida, T., Huang, L., Garcia-Vargas, J., Childs, B. H., Zinzani, P. L. & Dreyling, M., Sep 2017, In : Annals of Oncology. 28, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Differentiation of human astrocyte cell lines to model fragile X syndrome

Peteri, U-K., Roybon, L. & Castren, M., 2017, In : Glia. p. E122-E123

Research output: Contribution to journalMeeting AbstractResearch

DISC1 GENE NETWORK MUTATIONS IN MAJOR MENTAL ILLNESS

Sinha, V., Ortega-Alonso, A., Ukkola-Vuoti, L., Hovatta, I., Haukka, J., Torniainen, M., Therman, S., Cannon, T., Kaprio, J., Lonnqvist, J., Partonen, T., Isometsa, E., Paunio, T., Suvisaari, J. & Hennah, W., Oct 2017, In : European Neuropsychopharmacology. 27, p. S406-S407 2 p., M57.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Effect of Reference Panel in ID Score Regression Analysis of Lipid Traits in the Finnish Population

Hautakangas, H., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., 2017, In : Human Heredity. 83, 1, p. 10-10 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

EFFICACY AND SAFETY OF COPANLISIB IN PATIENTS WITH RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA: A SUBSET ANALYSIS OF THE CHRONOS-1 STUDY

Zinzani, P. L., Santoro, A., Leppa, S., Demeter, J., Follows, G. A., Lenz, G., Kim, W. S., Mollica, L., Nagler, A., Diong, C. P., Provenciio, M., Stevens, D. A., Trevarthen, D., Maagnoli, M., Cupit, L., Yin, S., Hiemeyer, F., Garcia-Vargas, J., Childs, B. H. & Dreyling, M., 26 Jun 2017, In : Haematologica. 102, p. 314-315 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Epigenetic clock at birth and psychiatric problems during early childhood

Suarez, A., Lahti, J., Czamara, D., Lahti, M., Knight, A. K., Girchenko, P., Hamalainen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Smith, A. K., Binder, E. B. & Räikkönen, K., Sep 2017, In : Psychoneuroendocrinology. 83S, p. 52-52 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Open Access
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Evaluating Robustness and Geographic Differences in Polygenic Risk in Finland

Kerminen, S., Koskela, J., Havulinna, A. S., Surakka, I., Martin, A. R., Palotie, A., Perola, M., Salomaa, V., Daly, M. J., Ripatti, S. & Pirinen, M., 2017, In : Human Heredity. 83, 1, p. 14-14 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Turkki, R., Bychkov, D., Linder, N., Isola, J., Joensuu, H. T. & Lundin, J., 1 Jul 2017, In : Cancer Research. 77, 13 Supplement, p. 673 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Fluoroquinolone-Related Adverse Events Resulting In Health Care Use And Costs: A Systematic Review

Kuula, L. SM., Viljemaa, K. M., Backman, J. T. & Blom, M. L. J., Oct 2017, In : Value in Health. 20, p. A669-A670 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

GDNF CONTROLS URETER LENGTH BY REGULATING COLLECTING DUCT PROGENITOR EXPANSION

Li, H., Jakobson, M., Ola, R., Sariola, H., Andressoo, J. & Kuure, S., Sep 2017, In : Pediatric Nephrology. 32, 9, p. 1651-1651 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

High Amount of PD-L1+Tumor Associated Macrophages Is Associated with Better Survival in Patients with Primary Testicular Lymphoma

Pollari, M., Bruck, O., Leivonen, S-K., Pellinen, T., Vahamurto, P., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, Suppl 1, p. Meeting Abstract: 2761 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Higher mortality in adult-onset asthma: a 15 year follow-up of a population-based matched cohort

Lemmetyinen, R., Karjalainen, J., But, A., Renkonen, R., Pekkanen, J., Haukka, J. & Toppila-Salmi, S., Aug 2017, In : Allergy : European journal of allergy and clinical immunology. 72, p. 391-391 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Homology between cancer and viral epitopes as criteria to design improved cancer vaccines

Capasso, C., Whalley, T., Marwah, V. S., Serafin, A., Fusciello, M., Feola, S., Martins, B., Greco, D., Szomolay, B. & Cerullo, V., Dec 2017, In : Annals of Oncology. 28, 1 p., 63P.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 Jun 2017, In : Haematologica. 102, p. 654-654 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

INCREASED INDOLEAMINE 2,3-DIOXYGENASE (IDO1) ACTIVITY IN EARLY CHRONIC PHASE CHRONIC MYELOGENOUS LEUKEMIA (CML-CP) IS REDUCED BY NILOTINIB THERAPY AND PREDICTS MOLECULAR RESPONSE

Sopper, S., Mustjoki, S., Gastl, G., Trajanoski, Z., Giles, F., Hochhaus, A., Janssen, J., Geisler, S., Fuchs, D. & Wolf, D., 26 Jun 2017, In : Haematologica. 102, p. 232-233 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Indoleamine 2,3-Dioxygenase (Ido1) activity is increased in early chronic phase Chronic Myelogenous Leukemia (CML) and predicts molecular response to nilotinib therapy

Sopper, S., Mustjoki, S., Geisler, S., Fuchs, D., Hackl, H., Trajanoski, Z., Hochhaus, A. & Wolf, D., Dec 2017, In : European Journal of Immunology. 47, p. 170-170 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Large Scale Epigenome Wide Meta-Analysis Reveals Dna Hypomethylation Patterns Associated With Asthma Throughout Childhood

Koppelman, G. H., Xu, C. -J., Soderhall, C., Bustamante, M., Baiz, N., Wright, J., Chatzi, L., Carlsen, K. L., Torrent, M., Llop, S., Porta, D., Fantini, M. P., Alenius, H., Jankipersadsing, S., Van Rijkom, B., Pershagen, G., Kogevinas, M., Kere, J., Anto, J. M., Bousquet, J. & 4 othersGuerra, S., Annesi-Maesano, I., Sunyer, J. & Melen, E., 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low Expression of T/NK-Cell Signature Predicts Poor Survival in Patients with Primary Testicular and Diffuse Large B-Cell Lymphoma

Leivonen, S-K., Pollari, M., Bruck, O., Pellinen, T., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

LOW IL-2 CONCENTRATION FAVORS GENERATION OF EARLY MEMORY T CELLS OVER TERMINAL EEFECTORS DURING CAR T-CELL EXPANSION

Luostarinen, A., Kaartinen, T., Maliniernii, P., Keto, J., Arvas, M., Belt, H., Koponen, J., Loskog, A., Mustjoki, S., Porkka, K., Yla-Herttuala, S. & Korhonen, M., May 2017, In : Cytotherapy. 19, 5, p. S8-S8 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review