Publications 1966 2019

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2018

(242) - Donor Plasma VEGF as a Biomarker for Early Graft Failure After Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Holmström, E., Tuuminen, R., Krebs, R., Rouvinen, E., Nykänen, A. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S103

Research output: Contribution to journalMeeting AbstractResearchpeer-review

(348) - Worldwide Experience of Adult Patients with Small Body Size Supported by a Continuous-Flow Left Ventricular Assist Device - An IMACS Analysis: ISHLT 38th Annual Meeting and Scientific Sessions

Lee, S., Xie, R., Lemstrom, K., Dickinson, M. G., Boeve, T., Leacche, M., Cowger, J., de By, T. & Kirklin, J. K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, Supplement, p. S145 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Cardiovascular autonomic function after simultaneous pancreas-kidney and kidney-alone transplantation in patients with diabetes

Paajanen, H., Bordino, M., Sandelin, A., Ekstrand, A., Lempinen, M., Forsblom, C., Bernardi, L. & Groop, P-H., 2018, (Accepted/In press) In : Diabetes Care. 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Clinical and Genetic Characterization of Canine Vitreous Degeneration

Kaukonen, M. & Lohi, H., Jul 2018, In : Investigative Ophthalmology & Visual Science. 59, 9, 2 p., 6042.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Donor Simvastatin Treatment Alters Protein Expression in the Recipient after Heart Transplantation: ISHLT 38th Annual Meeting and Scientific Sessions

Lukac, J., Holmström, E., Joenväärä, S., Saraswat, M., Krebs, R., Tohmola, T., Nykänen, A., Renkonen, R. & Lemström, K., Apr 2018, In : Journal of Heart and Lung Transplantation. 37, 4, p. S169-S170 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Efficient fine-mapping to identify causal genetic variants and quantify their contribution to complex phenotypes

Benner, C., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., Oct 2018, In : Genetic Epidemiology. 42, 7, p. 688-689 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Enantiospecific Pharmacogenomics of Fluvastatin

Hirvensalo, P., Tornio, A., Neuvonen, M., Kiander, W., Kidron, H., Paile-Hyvärinen, M., Tapaninen, T., Backman, J. & Niemi, M., May 2018, In : Basic & Clinical Pharmacology & Toxicology. 123, p. 7-7 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Oncolytic Adenoviruses Encapsulated into the Extracellular Vesicles as Carriers for Cancer Drug Delivery

Garofalo, M., Saari, H., Somersalo, P., Crescenti, D., Kuryk, L., Aksela, L., Capasso, C., Madetoja, M., Koskinen, K., Makitie, A., Jalasvuori, M., Cerullo, V., Ciana, P. & Yliperttula, M., May 2018, In : Molecular therapy. 26, 5, p. 203-203 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Role of CDNF in SOD1-G93A Mouse Model of Amyotrophic Lateral Sclerosis

Voutilainen, M. H., De Lorenzo, F., Montonen, E., Tuominen, R. K., Lindholm, D., Sendtner, M. & Saarma, M., Apr 2018, In : Cell Transplantation. 27, 4, p. 717-718 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2017

Changes in risky alcohol use and sickness absence

Ervasti, J., Kivimäki, M., Pentti, J., Halonen, J. I., Vahtera, J. & Virtanen, M., Nov 2017, In : European Journal of Public Health. 27, suppl. 3, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Characterization of Immunological Profiles with Clinical Significance in Patients with Classical Hodgkin Lymphoma

Karihtala, K., Leivonen, S-K., Karjalainen-Lindsberg, M-L. & Leppa, S., 7 Dec 2017, In : Blood. 130, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CHILDHOOD ADVERSITY, ADULT SOCIOECONOMIC STATUS AND RISK OF WORK DISABILITY - A PROSPECTIVE COHORT STUDY

Kivimaki, M., Vahtera, J., Pentti, J., Virtanen, M., Ervasti, J. & Lallukka, T., Sep 2017, In : Journal of Epidemiology & Community Health. 71, Suppl. 1, p. A61-A61 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CHRONIC MYELOID LEUKEMIA PATIENTS WERE NOT DIFFERENT IN MOLECULAR RELAPSE AFTER STOPPING IMATINIB IN MR4 WHETHER RESIDUAL DISEASE WAS DETECTED OR NOT - WHEN ADJUSTING FOR NUMBER OF CONTROL TRANSCRIPTS

Pfirrmann, M., Mahon, F-X., Guilhot, J., Richter, J., Almeida, A., Janssen, J. J., Mayer, J., Koskenvesa, P., Panayiotidis, P., Olsson-Stromberg, U., Berger, M. G., Diamond, J., Ehrencrona, H., Kairisto, V., Polakova, K. M., Mueller, M. C., Mustjoki, S., Hochhaus, A., Saussele, S. & Hjorth-Hansen, H., 26 Jun 2017, In : Haematologica. 102, p. 153-153 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CLINICAL AND IMMUNOLOGICAL EFFECTS OF NILOTINIB IN COMBINATION WITH PEGYLATED INTERFERON-A2B IN PATIENTS WITH SUBOPTIMAL MOLECULAR RESPONSE ON IMATINIB (NORDDUTCHCML009)

Geelen, I., Olsson-Stromberg, U., Mustjoki, S., Richter, J., Blijlevens, N., Smit, W., Gjertsen, B., Gedde-Dahl, T., Markevarn, B., Koppes, M., Westerweel, P., Janssen, J. & Hjorth-Hansen, H., 26 Jun 2017, In : Haematologica. 102, p. 435-435 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Copanlisib (COP) in patients with relapsed or refractory indolent B-cell lymphoma: primary results of the pivotal Chronos-1 study

Dreyling, M., Santoro, A., Mollica, L., Leppa, S., Follows, G. A., Lenz, G., Kim, W. S., Nagler, A., Panayiotidis, P., Demeter, J., Ozcan, M., Kosinova, M., Bouabdallah, K., Morschhauser, F., Stevens, D. A., Trevarthen, D., Giurescu, M., Kupit, L., Childs, B. H. & Zinzani, P. L., Sep 2017, In : Oncology research and treatment. 40, p. 12-12 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Copanlisib in patients with relapsed or refractory follicular lymphoma.

Dreyling, M. H., Santoro, A., Leppa, S., Demeter, J., Follows, G., Lenz, G., Kim, W. S., Mollica, L., Nagler, A., Diong, C. P., Provencio, M., Stevens, D. A., Trevarthen, D., Magagnoli, M., Cupit, L., Yin, S., Hiemeyer, F., -Vargas, J. E. G., Childs, B. H. & Zinzani, P. L., 20 May 2017, In : Journal of Clinical Oncology. 35, 5 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Copanlisib treatment in patients with relapsed or refractory indolent B-cell lymphoma: Subgroup analyses from the CHRONOS-1 study

Provencio Pulla, M., Santoro, A., Mollica, L., Leppa, S., Follows, G., Lenz, G., Kim, W. S., Nagler, A., Panayiotidis, P., Demeter, J., Ozcan, M., Kosinova, M., Bouabdallah, K., Morschhauser, F., Ishida, T., Huang, L., Garcia-Vargas, J., Childs, B. H., Zinzani, P. L. & Dreyling, M., Sep 2017, In : Annals of Oncology. 28, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Differentiation of human astrocyte cell lines to model fragile X syndrome

Peteri, U-K., Roybon, L. & Castren, M., 2017, In : Glia. p. E122-E123

Research output: Contribution to journalMeeting AbstractResearch

DISC1 GENE NETWORK MUTATIONS IN MAJOR MENTAL ILLNESS

Sinha, V., Ortega-Alonso, A., Ukkola-Vuoti, L., Hovatta, I., Haukka, J., Torniainen, M., Therman, S., Cannon, T., Kaprio, J., Lonnqvist, J., Partonen, T., Isometsa, E., Paunio, T., Suvisaari, J. & Hennah, W., Oct 2017, In : European Neuropsychopharmacology. 27, p. S406-S407 2 p., M57.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Effect of Reference Panel in ID Score Regression Analysis of Lipid Traits in the Finnish Population

Hautakangas, H., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., 2017, In : Human Heredity. 83, 1, p. 10-10 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

EFFICACY AND SAFETY OF COPANLISIB IN PATIENTS WITH RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA: A SUBSET ANALYSIS OF THE CHRONOS-1 STUDY

Zinzani, P. L., Santoro, A., Leppa, S., Demeter, J., Follows, G. A., Lenz, G., Kim, W. S., Mollica, L., Nagler, A., Diong, C. P., Provenciio, M., Stevens, D. A., Trevarthen, D., Maagnoli, M., Cupit, L., Yin, S., Hiemeyer, F., Garcia-Vargas, J., Childs, B. H. & Dreyling, M., 26 Jun 2017, In : Haematologica. 102, p. 314-315 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Epigenetic clock at birth and psychiatric problems during early childhood

Suarez, A., Lahti, J., Czamara, D., Lahti, M., Knight, A. K., Girchenko, P., Hamalainen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Smith, A. K., Binder, E. B. & Räikkönen, K., Sep 2017, In : Psychoneuroendocrinology. 83S, p. 52-52 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Open Access
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Evaluating Robustness and Geographic Differences in Polygenic Risk in Finland

Kerminen, S., Koskela, J., Havulinna, A. S., Surakka, I., Martin, A. R., Palotie, A., Perola, M., Salomaa, V., Daly, M. J., Ripatti, S. & Pirinen, M., 2017, In : Human Heredity. 83, 1, p. 14-14 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Turkki, R., Bychkov, D., Linder, N., Isola, J., Joensuu, H. T. & Lundin, J., 1 Jul 2017, In : Cancer Research. 77, 13 Supplement, p. 673 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

GDNF CONTROLS URETER LENGTH BY REGULATING COLLECTING DUCT PROGENITOR EXPANSION

Li, H., Jakobson, M., Ola, R., Sariola, H., Andressoo, J. & Kuure, S., Sep 2017, In : Pediatric Nephrology. 32, 9, p. 1651-1651 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

High Amount of PD-L1+Tumor Associated Macrophages Is Associated with Better Survival in Patients with Primary Testicular Lymphoma

Pollari, M., Bruck, O., Leivonen, S-K., Pellinen, T., Vahamurto, P., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Higher mortality in adult-onset asthma: a 15 year follow-up of a population-based matched cohort

Lemmetyinen, R., Karjalainen, J., But, A., Renkonen, R., Pekkanen, J., Haukka, J. & Toppila-Salmi, S., Aug 2017, In : Allergy : European journal of allergy and clinical immunology. 72, p. 391-391 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Homology between cancer and viral epitopes as criteria to design improved cancer vaccines

Capasso, C., Whalley, T., Marwah, V. S., Serafin, A., Fusciello, M., Feola, S., Martins, B., Greco, D., Szomolay, B. & Cerullo, V., Dec 2017, In : Annals of Oncology. 28, 1 p., 63P.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 Jun 2017, In : Haematologica. 102, p. 654-654 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

INCREASED INDOLEAMINE 2,3-DIOXYGENASE (IDO1) ACTIVITY IN EARLY CHRONIC PHASE CHRONIC MYELOGENOUS LEUKEMIA (CML-CP) IS REDUCED BY NILOTINIB THERAPY AND PREDICTS MOLECULAR RESPONSE

Sopper, S., Mustjoki, S., Gastl, G., Trajanoski, Z., Giles, F., Hochhaus, A., Janssen, J., Geisler, S., Fuchs, D. & Wolf, D., 26 Jun 2017, In : Haematologica. 102, p. 232-233 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Indoleamine 2,3-Dioxygenase (Ido1) activity is increased in early chronic phase Chronic Myelogenous Leukemia (CML) and predicts molecular response to nilotinib therapy

Sopper, S., Mustjoki, S., Geisler, S., Fuchs, D., Hackl, H., Trajanoski, Z., Hochhaus, A. & Wolf, D., Dec 2017, In : European Journal of Immunology. 47, p. 170-170 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Large Scale Epigenome Wide Meta-Analysis Reveals Dna Hypomethylation Patterns Associated With Asthma Throughout Childhood

Koppelman, G. H., Xu, C. -J., Soderhall, C., Bustamante, M., Baiz, N., Wright, J., Chatzi, L., Carlsen, K. L., Torrent, M., Llop, S., Porta, D., Fantini, M. P., Alenius, H., Jankipersadsing, S., Van Rijkom, B., Pershagen, G., Kogevinas, M., Kere, J., Anto, J. M., Bousquet, J. & 4 othersGuerra, S., Annesi-Maesano, I., Sunyer, J. & Melen, E., 2017, In : American Journal of Respiratory and Critical Care Medicine. 195, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low Expression of T/NK-Cell Signature Predicts Poor Survival in Patients with Primary Testicular and Diffuse Large B-Cell Lymphoma

Leivonen, S-K., Pollari, M., Bruck, O., Pellinen, T., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

LOW IL-2 CONCENTRATION FAVORS GENERATION OF EARLY MEMORY T CELLS OVER TERMINAL EEFECTORS DURING CAR T-CELL EXPANSION

Luostarinen, A., Kaartinen, T., Maliniernii, P., Keto, J., Arvas, M., Belt, H., Koponen, J., Loskog, A., Mustjoki, S., Porkka, K., Yla-Herttuala, S. & Korhonen, M., May 2017, In : Cytotherapy. 19, 5, p. S8-S8 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

PAIN AND ROUTES OF EXIT OUT OF PAID EMPLOYMENT AMONG BRITISH CIVIL SERVANTS: A FOLLOW-UP STUDY 1985-2013

Lallukka, T. L., Manty, M. M., Cooper, C. C., Fleischmann, M. F., Kouvonen, A. K., Head, J. H. & Halonen, J. I. H., Sep 2017, In : Journal of Epidemiology & Community Health. 71, Suppl.1, p. A75-A76 2 p., P55.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

PHENOTYPIC TRANSLATION OF THE DISC1 NETWORK HIGHLIGHTS THE ROLE OF THE NDE1 LOCUS, WITH PHARMACOLOGICAL IMPLICATIONS

Hennah, W., Bradshaw, N., Pankakoski, M., Ortega-Alonso, A., Torniainen, M., Paunio, T., Suvisaari, J., Lonnqvist, J. & Haukka, J., Oct 2017, In : European Neuropsychopharmacology. 27, p. S510-S511 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Representational similarity analysis of EEG and fMRI responses to face identities and emotional expressions

Ölander, K., Muukkonen, I., Numminen, J. & Salmela, V., 2017, In : Journal of Vision. 17, 10, p. 271 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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ST-segment elevation in baseline electrocardiogram predicts mortality in cardiogenic shock

Javanainen, T., Tolppanen, HEV., Harjola, VP., Lassus, J., Tarvasmäki, T., Nieminen, MS., Spinar, J., Sionis, A., Banaszewski, M. & Jurkko, R., 2017, In : European Journal of Heart Failure. 19, p. 216-217 2 p., P939.

Research output: Contribution to journalMeeting AbstractResearch

TELOMERE SHORTENING IN CD34+38-BCR-ABL POSITIVE BONE MARROW CELLS FROM NEWLY DIAGNOSED PATIENTS WITH CML CORRELATES WITH THE CLONE SIZE OF THE LEUKEMIC STEM CELL COMPARTMENT

Bouillon, A. -S., Ferreira, M. V., Awad, S. A., Richter, J., Hjorth-Hansen, H., Hummel, S., Schemionek, M., Mustjoki, S., Beier, F. & Bruemmendorf, T. H., 26 Jun 2017, In : Haematologica. 102, p. 231-232 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Th1/2 Immune Response Signature Predicts Outcome after Dose-Dense Immunochemotherapy in Patients with High Risk Diffuse Large B-Cell Lymphoma - Results from Nordic Lymphoma Group Trials

Autio, M., Leivonen, S-K., Jorgensen, J. M., Karjalainen-Lindsberg, M-L., Beiske, K., Holte, H. & Leppä, S., 7 Dec 2017, In : Blood. 130, 2 p., 4008.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The 107 kD ANO5 protein is decreased in anoctaminopathy patients

Vihola, A., Luque, H., Savarese, M., Penttila, S., Lindfors, M., Leturcq, F., Eymard, B., Tasca, G., Brais, B., Conte, T., Charton, K., Richard, I. & Udd, B., Oct 2017, In : Neuromuscular Disorders. 27, p. S144-S145 2 p.

Research output: Contribution to journalMeeting AbstractResearch

The impact of forced migration on mortality and mental health: a cohort study of 242,075 Finns

Haukka, J., Suvisaari, J., Sarvimaki, M., Salokangas, H. & Martikainen, P., Nov 2017, In : European Journal of Public Health. 27, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The living environment shapes intestinal microbial communities and immune responses in a mouse model

Ottman, N., Ruokolainen, L., Suomalainen, A., Karisola, P., Lehtimäki, J., Lehto, M., Hanski, I., Alenius, H. & Fyhrquist, N., Aug 2017, In : Allergy : European journal of allergy and clinical immunology. 72, p. 497-497 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Triplets, birthweight and left-handedness

Heikkila, K., Van Beijsterveldt, T., Haukka, J., Iivanainen, M., Saari-Kemppainen, A., Boomsma, D., Yokoyama, Y. & Vuoksimaa, E., Nov 2017, In : Behavior Genetics. 47, 6, p. 686-686 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Uptake and functionality of prostate cancer extracellular vesicles depends on the metastatic stage of the parent cells

Lazaro Ibanez, E., Neuvonen, K. M., Takatalo-Laine, S. M., Thanigai Arasu, U., Capasso, C., Rhim, J., Rilla, K., Yliperttula, M. L. & Siljander, P. R-M., May 2017, In : Journal of Extracellular Vesicles. 6, sup1

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Wnt pathway activation in 3D nephron progenitor culture facilitates self-organization, expansion, and differentiation

Dapkunas, A., Rantanen, V., Kuure, S., Sainio, K. & Sariola, H., Jul 2017, In : Mechanisms of Development. 145, p. S162-S163 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2016

A New Computational Method to Predict Long-Term Minimal Residual Disease and Molecular Relapse after TKI-Cessation in CML

Glauche, I., Liebscher, H., Baldow, C., Kuhn, M., Schulze, P., Haehnel, T., Voskanyan, A., Guilhot, J., Dulucq, S., von Bubnoff, N., Saussele, S., Mustjoki, S., Jost, P. J., Guilhot, F., Mahon, F-X. & Roeder, I., 2 Dec 2016, In : Blood. 128, 22, 5 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review