Publications 1966 2019

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Meeting Abstract
2012

Somatic PTPRT and ANGPT2 Mutations in Large Granulocyte Leukemia

Andersson, E. I., Eldfors, S., Koskela, H. L. M., Ellonen, P., Olson, T., Jerez, A., Clemente, M. J., Kallioniemi, O., Porkka, K., Loughran, T. P., Maciejewski, J. P., Heckman, C. & Mustjoki, S., 16 Nov 2012, In : Blood. 120, 21, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Use of exon-based transcriptome profiling to identify novel signaling pathways and survival-associated genes in diffuse large B-cell lymphoma

Leppa, S., Taskinen, M., Koivula, S., Chen, P., Louhimo, R., Delabie, J., Karjalainen-Lindsberg, M-L., Bjorkholm, M., Fluge, O., Pedersen, L. M., Rydstrom, K., Jerkeman, M., Eriksson, M., Hautaniemi, S., Holte, H. & Nordic Lymphoma Grp, 20 May 2012, In : Journal of Clinical Oncology. 30, 15, 1 p., Meeting Abstract: 8074.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2011

(18)FDG PET/CT AFTER INTENSIFIED CHEMO-IMMUNOTHERAPY IN DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL), AGED 18-65 YEARS WITH AAIPI 2-3. POSITIVE OR INDETERMINATE LESIONS HAVE A LOW POSITIVE PREDICTIVE VALUE. A NORDIC PHASE II SUBSTUDY

Holte, H., Bogsrud, T., Leppa, S., Laukka, M., Bjorkholm, M., Jacobsson, H., Jyrkkio, S., Seppanen, M., Jerkeman, M., Brun, E., Fluge, O. & Pedersen, L. M., Jun 2011, In : Annals of Oncology. 22, p. 159-159 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Addition of Rituximab to Chemotherapy Alters the Prognostic Impact of Tumor-Associated Macrophages in Diffuse Large B-Cell Lymphoma

Riihijarvi, S., Poyhonen, M., Taskinen, M., Karjalainen-Lindsberg, M-L. & Leppa, S., 18 Nov 2011, In : Blood. 118, 21, p. 1139-1139 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Age-Adjusted Combined Immunochemotherapy without Radiotherapy in Newly Diagnosed PCNSL - A Phase II Trial of the Nordic Lymphoma Group

Pulczynski, E. J., Kamper, P., Fagerli, U-M., Erlanson, M., Kuittinen, O., Fossa, A., Ostenstad, B., Fluge, O., Maisenholder, M., Hagberg, H., Eriksson, M., Nordstrom, M. & Leppa, S., 18 Nov 2011, In : Blood. 118, 21, p. 696-696 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

ALEMTUZUMAB DOES NOT AFFECT HEMATOPOIETIC RECOVERY AFTER AUTOLOGOUS STEM CELL TRANSPLANTATION IN T-CELL LYMPHOMA: DATA FROM THE ACT-1 TRIAL

Lauritzsen, G. F., Da Silva, M. G., Leppa, S., Pezzutto, A., Relander, T., Weidmann, E., Van Gelder, M., Doorduijn, J., Hansen, P., Altmann, B., Toldbod, H. & D'Amore, F., Jun 2011, In : Annals of Oncology. 22, suppl 4, p. 232-232 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Clinicopathological Differences Between Asian and Western Patients with De Novo Diffuse Large B Cell Lymphoma Treated with R-CHOP

Sinclair, N., Beltran, B. E., Song, M-K., Ilic, I., Leppa, S., Nyman, H., Uccella, S., Seki, R., Li, J., Treaba, D. O., Butera, J. N. & Castillo, J. J., 18 Nov 2011, In : Blood. 118, 21, p. 1144-1145 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

First Interim Safety Analysis of a Phase III Randomized Trial in Newly Diagnosed Systemic Peripheral T-Cell Lymphoma Treated with CHOP Chemotherapy with or without Alemtuzumab and Consolidated by Autologous Hematopoietic Stem Cell Transplant

d'Amore, F., da Silva, M. G., Leppa, S., Relander, T., Pezzutto, A., Lauritzsen, G. F., Weidmann, E., Van Gelder, M., Merup, M., Hagberg, H., Fagerli, U-M., Brown, P. D. N., Hansen, P. B., Mariz, J. M., Jankovska, M., Walewski, J., Doorduijn, J., Van Hoof, A., Christiansen, I., Jyrkkio, S. & 20 othersKluin-Nelemans, J. C., Kooy, M. V. M., Fijnheer, R., Stevens, W., Zijlstra, J., Bohmer, L., Lugtenburg, P. J., Grube, M., Prochazka, V., Salek, D., Greil, R., Trumper, L., Wulf, G., Altmann, B., Ziepert, M., Loeffler, M., Jantunen, E., Hopfinger, G., Van den Neste, E. & Toldbod, H., 18 Nov 2011, In : Blood. 118, 21, p. 1755-1755 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Histopathological features of tumor-negative lymph nodes from oral cancer patients without metastatic disease

Vered, M., Schiby, G., Bello, I., Dayan, D., Rytkoenen, A. & Salo, T., Aug 2011, In : Virchows Archiv. 459, p. S119-S119 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Hyperglycaemic E1-DN mice develop albuminuria and glomerular injury

Hyvonen, M. E., Ustinov, J., Otonkoski, T., Miettinen, P. J. & Lehtonen, S., Sep 2011, In : Diabetologia. 54, p. S432-S432 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Inhibition of HER2 Positive Breast Cancer Cells by Drug Screening

Nyberg, S., Hongisto, V., Tadele, D. S., Leivonen, S. K., Edgren, H., Kallioniemi, O., Borresen-Dale, A. L., Perala, M. & Sahlberg, K. K., Sep 2011, In : European Journal of Cancer. 47, p. S330-S331 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

INTEGRATIVE GENOMIC PROFILING OF HIGH-RISK DIFFUSE LARGE B-CELL LYMPHOMA PATIENTS LESS THAN 65 YEARS OLD TREATED WITH DOSE-DENSE CHEMOIMMUNOTHERAPY AND CNS PROPHYLAXIS

Koivula, S., Taskinen, M., Louhimo, R., Chen, P., Delabie, J., Holte, H., Karjalainen-Lindsberg, M., Bjorkholm, M., Fluge, O., Pedersen, L. M., Jerkeman, M., Eriksson, M., Hautaniemi, S. & Leppa, S., Jun 2011, In : Annals of Oncology. 22, p. 207-207 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Myoma organotypic model: novel in vitro and in vivo applications

Salo, T., Teppo, S., Nurmenniemi, S., Bitu, C., Vered, M., Dayan, D. & Nyberg, P., Aug 2011, In : Virchows Archiv. 459, p. S36-S36 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

PROGNOSTIC IMPACT OF TUMOR-ASSOCIATED MACROPHAGES ON SURVIVAL OF DIFFUSE LARGE B-CELL LYMPHOMA PATIENTS TREATED WITH HIGH-DOSE CHEMOTHERAPY SUPPORTED WITH AUTOLOGOUS STEM CELL TRANSPLANTATION

Poyhonen, M., Taskinen, M., Karjalainen-Lindsberg, M., Jantunen, E., Kosma, V. & Leppa, S., Jun 2011, In : Annals of Oncology. 22, p. 145-146 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells

Ostling, P., Leivonen, S-K., Aakula, A., Kohonen, P., Makela, R., Hagman, Z., Edsjo, A., Kangaspeska, S., Edgren, H., Nicorici, D., Bjartell, A., Ceder, Y., Perala, M. & Kallioniemi, O., 15 Apr 2011, In : Cancer Research. 71, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

WHITE MATTER CHANGES PREDICT STROKE RECURRENCE UP TO FIVE YEARS AFTER FIRST-EVER ISCHEMIC STROKE

Melkas, S., Sibolt, G., Oksala, N. K., Putaala, J., Pohjasvaara, T., Kaste, M., Karhunen, P. J. & Erkinjuntti, T., Sep 2011, In : European Journal of Neurology. 18, p. 37-37 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2010

Exon-Based Transcriptome Profiling Reveals Genes That Have Prognostic Impact on the Survival of Young High Risk Diffuse Large B-Cell/Follicular Grade 3 Lymphoma Patients Treated with Dose-Dense Chemoimmuno-therapy and CNS Prophylaxis. Results From a Nordic Lymphoma Group Phase II Study.

Koivula, S., Taskinen, M., Chen, P., Holte, H., Delabie, J., Karjalainen-Lindsberg, M-L., Bjorkholm, M., Fluge, O., Pedersen, L. M., Jerkeman, M., Eriksson, M., Hautaniemi, S. & Leppa, S., 19 Nov 2010, In : Blood. 116, 21, p. 1281-1281 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Poststroke delirium: prevalence, associated factors and influence on long term survival

Melkas, S., Laurila, J. V., Vataja, R., Oksala, N. K. J., Jokinen, H., Pohjasvaara, T., Leppavuori, A., Kaste, M., Karhunen, P. J. & Erkinjuntti, T., Sep 2010, In : European Journal of Neurology. 17, p. 133-133 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

R-CHOEP-14 x 6 Followed by Systemic CNS Prophylaxis for Diffuse Large B-Cell Lymphoma/Follicular Lymphoma Grade 3 with Age Adjusted IPI Score 2-3: Final Results of a Nordic Lymphoma Group Phase 2 Study Including 156 Patients Aged 18-65 Years

Holte, H., Leppa, S., Bjorkholm, M., Fluge, O., Jyrkkio, S., Delabie, J., Sundstrom, C., Karjalainen-Lindsberg, M-L., Erlanson, M., Kolstad, A., Fossa, A., Ostenstad, B., Lofvenberg, E., Nordstrom, M., Pedersen, L. M., Anderson, H., Jerkeman, M. & Eriksson, M., 19 Nov 2010, In : Blood. 116, 21, p. 1157-1157 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

RITUXIMAB MAINTENANCE FOR 2-YEARS SIGNIFICANTLY IMPROVES THE OUTCOME OF PATIENTS WITH UNTREATED HIGH TUMOR BURDEN FOLLICULAR LYMPHOMA AFTER RESPONSE TO IMMUNOCHEMOTHERAPY: RESULTS OF THE PRIMA STUDY

Salles, G., Catalano, J., Feugier, P., Offner, F., Bouabdallah, R., Caballero, D., Brice, P., Pedersen, L. M., Haioun, C., Belada, D., Delmer, A., Simpson, D., Tilly, H., Leppa, S., Soubeyran, P., Hagenbeek, A., Casasnovas, O., Tanin, I., Ferme, C., Gomes Da Silva, M. & 8 othersSebban, C., Pettengell, R., Estell, J., Milone, G., Sonnet, A., Lopez-Guillermo, A., Seymour, J. & Xerri, L., Jun 2010, In : Haematologica. 95, p. 229-229 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Sufficient and Timely Autologous Stem Cell Harvest After Chemoimmunotherapy with Alemtuzumab In Combination with Bi-Weekly CHOP as First Line Treatment In Systemic Peripheral T-Cell Lymphomas (PTCL): a Feasibility Analysis From the First Randomized Trial In Systemic PTCL (ACT trial)

d'Amore, F., da Silva, M. G., Leppa, S., Pezzutto, A., Relander, T., Lauritzsen, G. F., Weidmann, E., Van Gelder, M., Doorduijn, J., Kluin-Nelemans, J. C., Kooy, M. V. M., Fijnheer, R., de Weerdt, O., Brown, P. D. N., Hansen, P. B., Merup, M., Grube, M., Mariz, J. M., Walewski, J., Truemper, L. & 4 othersWulf, G., Jantunen, E., Hopfinger, G. & Prochazka, V., 19 Nov 2010, In : Blood. 116, 21, p. 992-993 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Systematic functional analysis of microRNAs by transfection of 1129 miRNAs into prostate cancer cells

Ostling, P., Leivonen, S-K., Aakula, A., Kohonen, P., Makela, R., Perala, M. & Kallioniemi, O., Apr 2010, In : Cancer Research. 70, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The Genetics of a Novel Form of Lafora Disease

Turnbull, J., Girard, J-M., Lohi, H., Chan, E., Wang, P., Tiberia, E., Omer, S., Ahmed, M., Bennett, C., Chakrabarty, A., Pencea, N., Zhao, X., Scherer, S., Ackerley, C. & Minassian, B., 27 Jul 2010, In : Neurology. 75, 4, p. 380-381 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The Immunohistochemical Profile and Other Prognostic Factors In Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma Treated with R-CHOP

Castillo, J. J., Beltran, B., Chung, J-S., Ilic, I., Leppa, S., Seki, R., Uccella, S., Xia, Z-G. & Butera, J. N., 19 Nov 2010, In : Blood. 116, 21, p. 1679-1679 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

TRAC gene expression analysis in in vitro drug metabolism screening

Rautio, J., Kotimaa, J. & Sirkia, M., 17 Jul 2010, In : Toxicology Letters. 196, p. S145-S146 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Updated Results of the PRIMA Study Confirms the Benefit of 2-Years Rituximab Maintenance In Follicular Lymphoma Patients Responding to Immunochemotherapy.

Salles, G. A., Catalano, J., Feugier, P., Offner, F. C., Bouabdallah, R., Caballero, D., Brice, P., Pedersen, L. M., Haioun, C., Belada, D., Delmer, A., Simpson, D., Tilly, H., Leppa, S., Soubeyran, P., Hagenbeek, A., Casasnovas, O., Intragumtornchai, T., Ferme, C., da Silva, M. G. & 8 othersSebban, C., Lister, A., Estell, J. A., Milone, G., Sonet, A., Lopez-Guillermo, A., Seymour, J. F. & Xerri, L., 19 Nov 2010, In : Blood. 116, 21, p. 746-746 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Visinin like 1 is differentially expressed in ureteric tips upon induction or disruption of branching

Ola, R., Jakobson, M., Perala, N., Kuure, S., Braunewell, K-H., Bridgewater, D., Rosenblum, N. D., Chilov, D., Sainio, K. & Sariola, H., Nov 2010, In : Differentiation. 80, suppl 1, p. S54-S54 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2009

MATRIX-METALLOPROTEINASES 2, 8 AND 9 IN SEVERE SEPSIS-A PROSPECTIVE LONGITUDINAL STUDY OF 44 PATIENTS

Gaddnas, F., Sutinen, M., Koskela, M., Salo, T., Laurila, J., Koivukangas, V., Ala-Kokko, T. & Oikarinen, A., Sep 2009, In : Intensive Care Medicine. 35, p. 168-168 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Mutations in TPM2 and TPM3 causing nemaline myopathy or arthrogryposis

Lehtokari, V. L., Kalimo, H., Pelin, K. & Wallgren-Pettersson, C., 2009, In : Neuromuscular Disorders. 19, 8-9, p. 587-588 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2008

AN ORGANOTYPIC MYOMA MODEL FOR ANALYSING CARCINOMA INVASION

Nurmenniemi, S., Nyberg, P., Sutinen, M., Risteli, J. & Salo, T., 2008, In : Anticancer Research. 28, 5C, p. 3469-3469 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Circulating markers of bone turnover in paediatric patients with inflammatory bowel disease

Vihinen, M., Raivio, T., Ashorn, M., Verkasalo, M. & Kolho, K-L., 2008, In : Scandinavian Journal of Gastroenterology. 43, suppl 244, p. 38-38 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

MATERNAL SERUM LOW PAPP-A IN THE FIRST TRIMESTER IS AN INDEPENDENT RISK FACTOR FOR ADVERSE PREGNANCY OUTCOME

Ryynanen, M., Peuhkurinen, S., Gissler, M., Marttala, J., Ignatius, J. & Laitinen, P., Dec 2008, In : American Journal of Obstetrics and Gynecology. 199, 6, p. S172-S172 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

PROTEASES AND COLLAGEN-DERIVED ANGIOGENESIS INHIBITORS IN THE TUMOR MICROENVIRONMENT

Nyberg, P. & Salo, T., 2008, In : Anticancer Research. 28, 5C, p. 3425-3425 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Atypical lymphocytic infiltration (lymphocytoma) of the inferior alveolar nerve: A case report

Siponen, M., Vartiamen, V. M., Salo, T., Rosberg, J. & Apaja-Sarkkinen, M., Aug 2007, In : Virchows Archiv. 451, 2, p. 552-552 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The enamel matrix derivative (Emdogain (R)) enhances human tongue carcinoma cells gelatinase production, migration and metastases formation

Laaksonen, M., Suojanen, J., Nurmenniemi, S., Laara, E., Sorsa, T. & Salo, T., Aug 2007, In : Virchows Archiv. 451, 2, p. 462-462 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2006

Elective single embryo transfer with cryopreservation improves overall outcome of IVF/ICSI program.

Veleva, Z., Tomas, C., Tapanainen, J. S. & Martikainen, H., Sep 2006, In : Fertility and Sterility : official journal of the American Fertility Society . 86, p. S252-S253 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Mmp-8 expression in females correlates with the improved survival of tongue cancer

Vaananen, A., Teronen, V., Maklin, H., Ristimaki, A., Thomas, G., Ylipalosaari, M., Kantola, S. K. & Salo, T. A., Aug 2006, In : Journal of Oral Pathology & Medicine. 35, 7, p. 429-429 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Oral lichen planus is associated with the use of thyroxin medication. A study of a Finnish population

Siponen, M. K., Huuskonen, L. K. J., Kantola, S. K. & Salo, T. A., Aug 2006, In : Journal of Oral Pathology & Medicine. 35, 7, p. 442-442 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Peptide G effectively inhibits cancer cell migration, tumor growth and membrane type-1 matrix metalloproteinase (MT1-MMP) activity.

Suojanen, J., Sorsa, T., Salo, T., Koivunen, E. & Pirila, E., 2006, In : Tumor Biology. 27, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2005

Collagen XVII promotes integrin-mediated squamous cell carcinoma transmigration: A novel role for alpha IIb integrin and tirofiban

Parikka, M., Kainulainen, T., Bruckner-Tuderman, L., Salo, T., Heino, J. & Tasanen, K., Sep 2005, In : Journal of Investigative Dermatology. 125, 3, p. A16-A16 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Fatty acid synthesis in mitochondria: new insights

Hiltunen, JK., Chen, ZJ., Miinalainen, IJ., Torkko, JM., Okubo, F., Airenne, TT. & Kastaniotis, AJ., 7 Mar 2005, In : FASEB Journal. 19, 5, p. A1371-A1371 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The structure of fixational eye movements during straight gaze path

Berg, M., Kojo, I., Simola, J. M. & Häkkinen, J. P., 2005, In : Journal of Vision. 5, 8, p. 589

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

The structure of fixational eye movements during turning gaze path

Kojo, I., Berg, M., Simola, J. M. & Häkkinen, J. P., 2005, In : Journal of Vision. p. 587

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
2004

Effects of contrast, saccade length and stimulus size on the visibility of colour breakup in field-sequential colour displays

Miettinen, I., Näsänen, R. & Häkkinen, J. P., 2004, In : Perception. 33, Supplement, p. 59-60

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Eye movements during text entry for small devices

Puhakka, M., Häkkinen, J. P. & Laarni, J., 2004, In : Perception. 33, Supplement, p. 171-172

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

ORGANIC BONE MATRIX IS DEGRADED BY OSTEOBLAST AND BREAST CANCER CELLS LEADING TO RELEASE OF TYPE I COLLAGEN FRAGMENTS IN VITRO

Parikka, V., Vaananen, A., Risteli, J., Salo, T., Vaananen, H. K. & Lehenkari, P., 2004, In : Calcified Tissue International. 74, p. S51-S51 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2003

Depth capture in natural environment

Kojo, I., Häkkinen, J. P. & Simola, J. M., 2003, In : Journal of Vision. 3, 9, p. 851a 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Does preknowledge of target depth affect visual processing?

Puhakka, M., Häkkinen, J. P. & Laarni, J., 2003, In : Journal of Vision. 3, p. 559a

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Gingival crevicular fluid collagenase-2 (MMP-8) test stick for chair-side monitoring of periodontitis.

Mantyla, P., Stenman, M., Kinane, D. F., Salo, T. & Sorsa, T., Jun 2003, In : Journal of Dental Research. 82, p. B112-B112 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review