Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications 1983 2019

2019

Acceptability of flavoured pharmaceutically non-active minitablets in pet cats tested with a rapid 3-portal acceptance test with and without food

Savolainen, S. M., Hautala, J. K., Junnila, J., Airaksinen, S., Juppo, A. M., Raekallio, M. R. & Vainio, O., 2019, (Submitted) In : Veterinary Journal.

Research output: Contribution to journalArticleScientificpeer-review

A nebulin super-repeat panel reveals stronger actin binding toward the ends of the super-repeat region

Laitila, J., Lehtonen, J., Lehtokari, V-L., Sagath, L., Wallgren-Pettersson, C., Grönholm, M. & Pelin, K., Jan 2019, In : Muscle & Nerve. 59, 1, p. 116-121 6 p.

Research output: Contribution to journalArticleScientificpeer-review

An ethnobotanical survey and antifungal activity of Piper guineense used for the treatment of fungal infections in West-African traditional medicine

Mgbeahuruike, E. E., Holm, Y., Vuorela, H., Amandikwa, C. & Fyhrquist, P., 30 Jan 2019, In : Journal of Ethnopharmacology. 229, p. 157-166 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Automatic methodologies to perform loading and release assays of anticancer drugs from mesoporous silicon nanoparticles

Pereira, S., Passos, M., Correia, A., Mäkilä, E., Salonen, J., Araujo, A., Almeida Santos, H. & Saraiva, M. L., 1 May 2019, In : Talanta. 196, p. 277-283 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells

Qi, S., Zhang, P., Ma, M., Yao, M., Wu, J., Mäkilä, E., Salonen, J., Ruskoaho, H. J., Xu, Y., Almeida Santos, H. & Zhang, H., 4 Jan 2019, In : Small. p. 1804332 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Dose-dependent effects of isoflurane on TrkB and GSK3β signaling: Importance of burst suppression pattern

Alitalo, O. A., Theilmann, W., Yorke, I. & Rantamäki, T. P. J., 16 Feb 2019, In : Neuroscience Letters. 694, p. 29-33

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Electrospun Fibrous Architectures for Drug Delivery, Tissue Engineering and Cancer Therapy

Ding, Y., Li, W., Zhang, F., Liu, Z., Zanjanizadeh Ezazi, N., Liu, D. & Almeida Santos, H., 10 Jan 2019, In : Advanced Functional Materials. 29, 2, p. 1802852 35 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Endocrine activities and adipogenic effects of bisphenol AF and its main metabolite

Skledar, D. G., Carino, A., Trontelj, J., Troberg, J., Distrutti, E., Marchiano, S., Tornasic, T., Zega, A., Finel, M., Fiorucci, S. & Maisic, L. P., Jan 2019, In : Chemosphere. 215, p. 870-880 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Enzyme Immobilization: Overcoming the Pitfalls of Cytochrome P450 Immobilization through the Use of Fusogenic Liposomes (Adv. Biosys. 1/2019)

Kiiski, I. M. A., Pihlaja, T. L. M., Urvas, L. M., Witos, J. M., Wiedmer, S. K., Jokinen, V. P. & Sikanen, T. M., 11 Jan 2019

Research output: Non-textual formDigital or Visual ProductsArt in non-art workpeer-review

Implementation of improved postoperative care decreases the mortality rate of operated mice after an abundant 6-hydroxydopamine lesion of nigrostriatal dopaminergic neurons

Koski, S. K., Leino, S., Rannanpää, S. K. & Salminen, O. S., 2019, (Accepted/In press) In : Scandinavian Journal of Laboratory Animal Science. 45, 1, 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Lääketieteellinen farmakologia ja toksikologia

Ruskoaho, H. J. (ed.), Hakkola, J. (ed.), Huupponen, R., Kantele-Häkkinen, A. M., Korpi, E. R., Moilanen, E., Piepponen, T. P., Tenhunen, O. & Vähäkangas, K., Jan 2019, 5. painos ed. Kustannus Oy Duodecim. 1286 p.

Research output: Book/ReportBookProfessional

Laser Activatable CuS Nanodots to Treat Multidrug-Resistant Bacteria and Release Copper Ion to Accelerate Wound Healing for Infected Chronic Nonhealing Wounds

Qiao, Y., Ping, Y., Zhang, H., Zhou, B., Liu, F., Yu, Y., Xie, T., Li, W., Zhong, D., Zhang, Y., Yao, K., Almeida Santos, H. & Zhou, M., 3 Jan 2019, In : ACS Applied Materials & Interfaces.

Research output: Contribution to journalArticleScientificpeer-review

Nuts and Bolts: Microfluidics for the Production of Biomaterials

Fontana, F., Oliveira Martins, J. P., Torrieri, G. & Almeida Santos, H., 3 Jan 2019, In : Advanced Materials Technologies.

Research output: Contribution to journalReview ArticleScientificpeer-review

Overcoming the Pitfalls of Cytochrome P450 Immobilization Through the Use of Fusogenic Liposomes

Kiiski, I. M. A., Pihlaja, T. L. M., Urvas, L. M., Wiedmer, S. K., Witos, J. M., Jokinen, V. P. & Sikanen, T. M., 11 Jan 2019, In : Advanced Biosystems. 3, 1, 6 p., 1800245.

Research output: Contribution to journalArticleScientificpeer-review

Process optimization of ecological probe sonication technique for production of rifampicin loaded niosomes

Khan, D. H., Bashir, S., Figueiredo, P. I., Almeida Santos, H., Khan, M. I. & Peltonen, L. J., Apr 2019, In : Journal of Drug Delivery Science and Technology. 50, p. 27-33 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Quantifying the interactions between biomimetic biomaterials - collagen I, collagen IV, laminin 521 and cellulose nanofibrils - by colloidal probe microscopy

Nugroho, R. W. N., Harjumäki, R., Zhang, X., Lou, Y-R., Yliperttula, M., Valle-Delgado, J. J. & Österberg, M., 1 Jan 2019, In : Colloids and Surfaces B: Biointerfaces. 173, p. 571-580 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Use of telephone and web interfaces of Interactive Response Technology at clinical investigator sites in clinical trials

Saarela, A-L., Walzer, A. & Juppo, A. M., 2019, (Accepted/In press) In : Clinical trials : journal of the Society for Clinical Trials.

Research output: Contribution to journalArticleScientificpeer-review

2018

3D printed UV light cured polydimethylsiloxane devices for drug delivery

Hollander, J., Hakala, R., Suominen, J., Moritz, N., Yliruusi, J. & Sandler, N., 15 Jun 2018, In : International Journal of Pharmaceutics. 544, 2, p. 433-442 10 p.

Research output: Contribution to journalArticleScientificpeer-review

A call for action: Improve reporting of research studies to increase the scientific basis for regulatory decision-making

Ågerstrand, M., Christiansen, S., Hanberg, A., Rudén, C., Andersson, L., Andersen, S., Appelgren, H., Bjørge, C., Clausen, I. H., Eide, D. M., Hartmann, N. B., Husøy, T., Halldórsson, H. P., Hagen, M., Ingre-Khans, E., Lillicrap, A. D., Beltoft, V. M., Mörk, A-K., Murtomaa-Hautala, M., Nielsen, E. & 8 othersÓlafsdóttir, K., Palomäki, J., Papponen, H., Reiler, E. M., Stockmann-Juvala, H., Suutari, T., Tyle, H. & Beronius, A., 3 Jan 2018, In : Journal of Applied Toxicology. 38, 5, p. 783-785 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation

Richardson, D., Itkonen, J., Nievas, J., Urtti, A. & Casteleijn, M. G., 10 Aug 2018, In : Scientific Reports. 8, 1, 11967 .

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Accurate Calibration in Multi-Material 3D Bioprinting for Tissue Engineering

Sodupe-Ortega, E., Sanz-Garcia, A., Pernia-Espinoza, A. & Escobedo-Lucea, C., 10 Aug 2018, In : Materials. 11, 8, 19 p., 1402.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Adenosine analogs bearing phosphate isosteres as human MDO1 ligands

Zhang, Y., Jumppanen, A. M., Maksimainen, M. M., Auno, A. S., Awol, Z., Ghemtio, L., Venkannagari, H., Lehtiö, L., Yli-Kauhaluoma, J., Xhaard, H. & Boije af Gennäs, G., 6 Apr 2018, In : Bioorganic & Medicinal Chemistry. 26, 8, p. 1588-1597 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Adjustable hardness of hydrogel for promoting vascularization and maintaining stemness of stem cells in skin flap regeneration

Sun, X., Zhang, H., He, J., Cheng, R., Cao, Y., Che, K., Cheng, L., Zhang, L., Pan, G., Ni, P., Deng, L., Zhang, Y., Almeida Santos, H. & Cui, W., Dec 2018, In : Applied materials today. 13, p. 54-63 10 p.

Research output: Contribution to journalArticleScientificpeer-review

A feasibility study of the toxic responses of human induced pluripotent stem cell-derived hepatocytes to phytochemicals

Smutný, T., Harjumäki, R., Kanninen, L., Yliperttula, M. L., Pávek, P. & Lou, Y-R., 11 Jun 2018, In : Toxicology in Vitro. 52, p. 94-105 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Alkaloid-rich crude extracts, fractions and piperamide alkaloids of Piper guineense possess promising antibacterial effects

Mgbeahuruike, E. E., Fyhrqvist, P. J., Vuorela, H. J., Julkunen-Tiitto, R. & Holm, Y. M., 2018, (Submitted) In : Antibiotics. 7

Research output: Contribution to journalArticleScientificpeer-review

Amphetamine primes enhanced motivation toward uncertain choices in rats with genetic alcohol preference

Oinio, V., Sundström, M., Bäckström, P., Uhari-Väänänen, J., Kiianmaa, K., Raasmaja, A. & Piepponen, P., May 2018, In : Psychopharmacology. 235, 5, p. 1361-1370 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Analytical tools for reliable in vitro and in vivo performance testing of drug nanocrystals

Tuomela, A., Saarinen, J., Hirvonen, J. & Peltonen, L., 2018, Nanoscale fabrication, optimization, scale-up and biological aspects of pharmaceutical nanotechnology. Grumezescu, A. M. (ed.). San Diego: Elsevier, p. 441-477 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

A national approach to medicines information research: a systematic review

Mononen, N. M., Järvinen, R., Hämeen-Anttila, K., Airaksinen, M. S. A., Bonhomme, C., Kleme, J. & Pohjanoksa-Mäntylä, M., Dec 2018, In : Research in Social and Administrative Pharmacy. 14, 12, p. 1106-1124 19 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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An immunological electrospun scaffold for tumor cell killing and healthy tissue regeneration

Liu, X., Zhang, H., Cheng, R., Gu, Y., Yin, Y., Sun, Z., Pan, G., Deng, Z., Yang, H., Deng, L., Cui, W., Almeida Santos, H. & Shi, Q., 16 Aug 2018, In : Materials Horizons. 5, 6, p. 1082-1091 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Antibacterial and antioxidative properties of different parts of garden rhubarb, blackcurrant, chokeberry and blue honeysuckle

Raudsepp, P., Kosar, J., Anton, D., Meremäe, K., Kapp, K., Laurson, P., Bleive, U., Kaldmäe, H., Roasto, M. & Püssa, T., 2018, In : Journal of the Science of Food and Agriculture.

Research output: Contribution to journalArticleScientificpeer-review

Antibioottiresistenssi - jätevedessä sen alku ja loppu

Elsilä, L., Feb 2018, In : Proviisorilehti. 1, p. 22-23 2 p.

Research output: Contribution to journalArticleProfessional

Open Access

Anti-Infective Effects of Wild Berries: Novel anti-bacterial biomolecules may protect against infections

Toivanen, M. & Tikkanen-Kaukanen, C., 2018, Microbiological Environmental Hygiene. Hakalehto, E. E. (ed.). Nova Science Publishers

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Antitumor effect of oncolytic virus and paclitaxel encapsulated in extracellular vesicles for lung cancer treatment

Garofalo, M., Saari, H., Somersalo, P., Crescenti, D., Kuryk, L., Aksela, L., Capasso, C., Madetoja, M., Koskinen, K., Oksanen, T., Mäkitie, A., Jalasvuori, M., Cerullo, V., Ciana, P. & Yliperttula, M., 1 Jun 2018, In : Journal of Controlled Release. 283, p. 223-234 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Antitumor-specific T-cell responses induced by oncolytic adenovirus ONCOS-102 (AdV5/3-D24-GM-CSF) in peritoneal mesothelioma mouse model

Kuryk, L., Moller, A-S. W., Garofalo, M., Cerullo, V., Pesonen, S., Alemany, R. & Jaderberg, M., Oct 2018, In : Journal of Medical Virology. 90, 10, p. 1669-1673 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Arginine-rich cell-penetrating peptides induce membrane multilamellarity and subsequently enter via formation of a fusion pore

Allolio, C., Magarkar, A., Jurkiewicz, P., Baxova, K., Javanainen, M., Mason, P. E., Sachl, R., Cebecauer, M., Hof, M., Horinek, D., Heinz, V., Rachel, R., Ziegler, C. M., Schröfel, A. & Jungwirth, P., 20 Nov 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 47, p. 11923-11928 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Attenuated dopaminergic neurodegeneration and motor dysfunction in hemiparkinsonian mice lacking the α5 nicotinic acetylcholine receptor subunit

Leino, S., Koski, S. K., Hänninen, R., Tapanainen, T., Rannanpää, S. & Salminen, O., 28 Jun 2018, In : Neuropharmacology. 138, p. 371-380 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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A versatile strategy for the synthesis of 4,5-dihydroxy-2,3-pentadione (DPD) and related compounds as potential modulators of bacterial quorum sensing

Stotani, S., Gatta, V., Medda, F., Padmanaban, M., Karawajzyk, A., Tammela, P. S. M., Giordanetto, F., Tzalis, D. & Collina, S., 6 Oct 2018, In : Molecules. 23, 10, 22 p., 2545.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Azulene-based compounds for targeting orexin receptors

Leino, T. O., Turku, A., Yli-Kauhaluoma, J. T., Kukkonen, J. P., Xhaard, H. & Wallén, E. A. A., 5 Sep 2018, In : European Journal of Medicinal Chemistry. 157, p. 88-100 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Bare laser-synthesized Au-based nanoparticles as nondisturbing surface-enhanced Raman scattering probes for bacteria identification

Kögler, M., Ryabchikov, Y. V., Uusitalo, S., Popov, A., Popov, A., Tselikov, G., Välimaa, A-L., Al-Kattan, A., Hiltunen, J., Laitinen, R., Neubauer, P., Meglinski, I. & Kabashin, A. V., Jul 2018, In : Journal of Biophotonics. 11, 7, 10 p., 201700225.

Research output: Contribution to journalArticleScientificpeer-review

Barriers and facilitators to medication adherence: a qualitative study with general practitioners

Kvarnström, K., Airaksinen, M. & Liira, H., Jan 2018, In : BMJ Open. 8, 1, 8 p., 015332.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Bentsodiatsepiinien pitkäaikaiskäyttö on vähentynyt

Kurko, T., Saastamoinen, L., Tuulio-Henriksson, A., Taiminen, T., Tiihonen, J., Airaksinen, M. & Hietala, J., 2018, In : Suomen lääkärilehti. 73, 20, p. 1292-1297 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Binding of Small Molecule Drugs to Porcine Vitreous Humor

Rimpelä, A-K., Reunanen, S., Hagström, M., Kidron, H. & Urtti, A., Jun 2018, In : Molecular Pharmaceutics. 15, 6, p. 2174-2179 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate-Induced Excitotoxicity

Liu, D., Chen, J., Jiang, T., Li, W., Huang, Y., Lu, X., Liu, Z., Zhang, W., Zhou, Z., Ding, Q., Almeida Santos, H., Yin, G. & Fan, J., 14 Feb 2018, In : Advanced Materials. 30, 14, 11 p., 1706032.

Research output: Contribution to journalArticleScientificpeer-review

Bioengineered Porous Silicon Nanoparticles@Macrophages Cell Membrane as Composite Platforms for Rheumatoid Arthritis

Fontana, F., Albertini, S., Correia, A., Kemell, M. L., Lindgren, R., Mäkilä, E., Salonen, J., Hirvonen, J. T., Ferrari, F. & Almeida Santos, H., 30 May 2018, In : Advanced Functional Materials. 28, 22, 10 p., 1801355.

Research output: Contribution to journalArticleScientificpeer-review

Biological treatment in ankylosing spondylitis in the Nordic countries during 2010-2016: a collaboration between five biological registries

DANBIO Registry, SRQ ARTIS Registry, ROB-FIN Registry, NOR-DMARD Registry & ICEBIO Registry, 2 Nov 2018, In : Scandinavian Journal of Rheumatology. 47, 6, p. 465-474 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements

Parkkila, P., Elderdfi, M., Bunker, A. & Viitala, T., 10 Jul 2018, In : Langmuir. 34, 27, p. 8081-8091 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Biotransformation of cyclodextrin-complexed semi-synthetic betulin derivatives by plant cells

Häkkinen, S., Nygren, H., Maiorova, N., Haavikko, R. H., Alakurtti, S., Yli-Kauhaluoma, J. T., Rischer, H. & Oksman-Caldentey, K-M., 1 Jul 2018, In : Planta Medica. 84, 9/10, p. 743-748 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Bridging the Knowledge of Different Worlds to Understand the Big Picture of Cancer Nanomedicines

Balasubramanian, V., Liu, Z., Hirvonen, J. T. & Almeida Santos, H., 10 Jan 2018, In : Advanced Healthcare Materials. 7, 1, p. 1700432 23 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Cancer-Targeted Oncolytic Adenoviruses for Modulation of the Immune System

Cerullo, V., Capasso, C., Vähä-Koskela, M., Hemminki, O. & Hemminki, A., 2018, In : Current Cancer Drug Targets. 18, 2, p. 124-138 15 p.

Research output: Contribution to journalReview ArticleScientificpeer-review