Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications

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2020

2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in Pseudomonas aeruginosa

McVey, A., Bartlett, S., Kajbaf, M., Pellacani, A., Gatta, V., Tammela, P., Spring, D. R. & Welch, M., 3 Apr 2020, In : International Journal of Molecular Sciences. 21, p. 2490 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

A Biomimetic 3D-Self-Forming Approach for Microvascular Scaffolds

Zhang, L., Xiang, Y., Zhang, H., Cheng, L., Mao, X., An, N., Zhang, L., Zhou, J., Deng, L., Zhang, Y., Sun, X., Santos, H. A. & Cui, W., 6 May 2020, In : Advanced Science. 7, 9, 10 p., 1903553.

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Open Access
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Age-associated changes in the immune system may influence the response to anti-PD1 therapy in metastatic melanoma patients

Kasanen, H., Hernberg, M., Mäkelä, S., Brück, O., Juteau, S., Kohtamäki, L., Ilander, M., Mustjoki, S. & Kreutzman, A., 8 Feb 2020, In : Cancer Immunology, Immunotherapy. 14 p.

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All-in-one microfluidic assembly of insulin-loaded pH-responsive nano-in-microparticles for oral insulin delivery

Costa, C., Liu, Z., Martins, J. P., Correia, A., Rahikkala, A. T. A., Li, W., Seitsonen, J., Ruokolainen, J., Hirvonen, S-P., Aguiar- Ricardo, A., Corvo, M. L. & Santos, H. A., 27 May 2020, In : Biomaterials Science. 8, p. 8 3270 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Amphiphilic Polypeptides for VEGF siRNA Delivery into Retinal Epithelial Cells

Osipova, O., Sharoyko, V., Zashikhina, N., Zakharova, N., Tennikova, T., Urtti, A. & Korzhikova-Vlakh, E., Jan 2020, In : Pharmaceutics. 12, 1, 17 p., 39.

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A new cell-based AI-2-mediated quorum sensing interference assay in screening of LsrK-targeted inhibitors

Gatta, V., Tomašič, T., Ilaš, J., Zidar, N., Peterlin Mašič, L., Barančoková, M., Frlan, R., Anderluh, M., Kikelj, D. & Tammela, P., 6 Feb 2020, In : ChemBioChem : a European journal of chemical biology.

Research output: Contribution to journalArticleScientificpeer-review

Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent

Serfozo, P., Wysocki, J., Gulua, G., Schulze, A., Ye, M., Liu, P., Jin, J., Bader, M., Myöhänen, T., Garcia Horsman, J. A. & Batlle, D., Jan 2020, In : Hypertension. 75, 1, p. 173-182 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Open Access
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Anti-influenza virus activity of benzo[d]thiazoles that target heat shock protein 90

Lamut, A., Gjorgjieva, M., Naesens, L., Liekens, S., Lillsunde, K-E., Tammela, P., Kikelj, D. & Tomašič, T., May 2020, In : Bioorganic Chemistry. 98, 8 p., 103733.

Research output: Contribution to journalArticleScientificpeer-review

A platform for studying the transfer of Chlamydia pneumoniae infection between respiratory epithelium and phagocytes

Kortesoja, M., Trofin, R. E. & Hanski, L., Apr 2020, In : Journal of Microbiological Methods. 171, 9 p., 105857.

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A scaffold replacement approach towards new sirtuin 2 inhibitors

Seifert, T., Malo, M., Kokkola, T., Steen, E. J. L., Meinander, K., Wallen, E. A. A., Jarho, E. M. & Luthman, K., 15 Jan 2020, In : Bioorganic & Medicinal Chemistry. 28, 2, 12 p., 115231.

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A smart microfluidic platform for rapid multiplexed detection of foodborne pathogens

Azinheiro, S., Kant, K., Shahbazi, M-A., Garrido-Maestu, A., Prado, M. & Dieguez, L., Aug 2020, In : Food Control. 114, 7 p., 107242.

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Assembling of the interfacial layer affects the physical and oxidative stability of faba bean protein-stabilized oil-in-water emulsions with chitosan

Liu, C., Pei, R., Peltonen, L. & Heinonen, M., May 2020, In : Food Hydrocolloids. 102, 11 p., 105614.

Research output: Contribution to journalArticleScientificpeer-review

Back Cover - Microvascular Scaffolds: A Biomimetic 3D‐Self‐Forming Approach for Microvascular Scaffolds (Adv. Sci. 9/2020)

Zhang, L., Xiang, Y., Zhang, H., Cheng, L., Mao, X., An, N., Zhang, L., Zhou, J., Deng, L., Zhang, Y., Sun, X., Santos, H. A. & Cui, W., 6 May 2020, In : Advanced Science. 7, 9, 1 p., 2070050.

Research output: Contribution to journalArticleScientific

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Behavioral responses of mGluR3-KO mice to the lipopolysaccharide-induced innate inflammatory reaction

Lainiola, M., Linden, A-M. & Aitta-aho, T., Mar 2020, In : Pharmacology, Biochemistry and Behavior. 190, 8 p., 172852.

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Bioadhesive supramolecular hydrogel from unprotected, short d,l-peptides with Phe-Phe and Leu-Asp-Val motifs

Cringoli, M. C., Romano, C., Parisi, E., Waddington, L. J., Melchionna, M., Semeraro, S., De Zorzi, R., Grönholm, M. & Marchesan, S., 11 Mar 2020, In : Chemical Communications. 56, 20, p. 3015-3018 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Cerebral dopamine neurotrophic factor-deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice

Lindahl, M., Chalazonitis, A., Palm, E., Pakarinen, E., Danilova, T., Pham, T. D., Setlik, W., Rao, M., Voikar, V., Huotari, J., Kopra, J., Andressoo, J-O., Piepponen, P. T., Airavaara, M., Panhelainen, A., Gershon, M. D. & Saarma, M., Feb 2020, In : Neurobiology of Disease. 134, 18 p., 104696.

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Chloroquine fumardiamides as novel quorum sensing inhibitors

Beus, M., Savijoki, K., Patel, J., Yli-Kauhaluoma, J., Fallarero, A. & Zorc, B., 12 Jun 2020, In : Bioorganic & Medicinal Chemistry Letters. 30, 16, 8 p., 127336.

Research output: Contribution to journalArticleScientificpeer-review

Cholesterol Reduces Partitioning of Antifungal Drug Itraconazole into Lipid Bilayers

Poojari, C., Zak, A., Dzieciuch-Rojek, M., Bunker, A., Kepczynski, M. & Rog, T., 19 Mar 2020, In : Journal of Physical Chemistry B. 124, 11, p. 2139-2148 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells in a three-dimensional environment

Salonius, E., Kontturi, L., Laitinen, A., Haaparanta, A-M., Korhonen, M., Nystedt, J., Kiviranta, I. & Muhonen, V., Apr 2020, In : Journal of Cellular Physiology. 235, 4, p. 3497-3507 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Chronic two-fold elevation of endogenous GDNF levels is safe and enhances motor and dopaminergic function in aged mice

Turconi, G., Kopra, J., Võikar, V., Kulesskaya, N., Vilenius, C., Piepponen, T. P. & Andressoo, J-O., 11 Apr 2020, In : Molecular therapy-Methods & clinical development. 17, p. 831-842 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Clinical Study of Nanofibrillar Cellulose Hydrogel Dressing for Skin Graft Donor Site Treatment

Koivuniemi, R., Hakkarainen, T., Kiiskinen, J., Kosonen, M., Vuola, J., Valtonen, J., Luukko, K., Kavola, H. & Yliperttula, M., 7 Feb 2020, In : Advances in wound care. 9, 4, p. 199-210 12 p.

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Colorectal Cancer Triple Co-culture Spheroid Model to Assess the Biocompatibility and Anticancer Properties of Polymeric Nanoparticles

Bauleth-Ramos, T., Feijão, T., Gonçalves, A., Shahbazi, M-A., Liu, Z., Barrias, C., Oliveira, M. J., L. Granja, P., Santos, H. A. & Sarmento, B., 10 Jul 2020, In : Journal of Controlled Release. 323, p. 398-411 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Comparison of clinically relevant oncolytic virus platforms for enhancing T-cell therapy of solid tumors

Cervera-Carrascon, V., Quixabeira, D. C. A., Havunen, R., Santos, J. M., Kutvonen, E., Clubb, J. H. A., Siurala, M., Heiniö, C., Zafar, S., Koivula, T., Lumen, D., Vaha, M., Garcia-Horsman, A., Airaksinen, A. J., Sorsa, S., Anttila, M., Hukkanen, V., Kanerva, A. & Hemminki, A., 19 Mar 2020, In : Molecular Therapy - Oncolytics.

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Deciphering Imidazoline Off-Targets by Fishing in the Class A of GPCR field

Djikic, T., Vucicevic, J., Laurila, J., Radi, M., Veljkovic, N., Xhaard, H. & Nikolic, K. M., 20 Feb 2020, In : Molecular informatics.

Research output: Contribution to journalArticleScientificpeer-review

Design, synthesis and biological evaluation of novel DNA gyrase Inhibitors and their siderophore mimic conjugates

Lamut, A., Cruz, C. D., Skok, Ž., Barančoková, M., Zidar, N., Zega, A., Peterlin Mašič, L., Ilaš, J., Tammela, P., Kikelj, D. & Tomašič, T., Jan 2020, In : Bioorganic Chemistry. 95, 13 p., 103550.

Research output: Contribution to journalArticleScientificpeer-review

Design, Synthesis and Characterization of a PEGylated Stanozolol for Potential Therapeutic Applications

Vergallo, C., Torrieri, G., Provenzani, R., Miettinen, S., Moslova, K., Varjosalo, M., Cristiano, M. C., Fresta, M., Celia, C., Santos, H. A., Cilurzo, F. & Di Marzio, L., 5 Jan 2020, In : International Journal of Pharmaceutics. 573, 11 p., 118826.

Research output: Contribution to journalArticleScientificpeer-review

Design and application of oncolytic viruses for cancer immunotherapy

Ylösmäki, E. & Cerullo, V., Oct 2020, In : Current Opinion in Biotechnology. 65, p. 25-36 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Design and synthesis of lipid-mimetic cationic iridium complexes and their liposomal formulation for in vitro and in vivo application in luminescent bioimaging

Shakirova, J. R., Sadeghi, A., Koblova, A. A., Chelushkin, P. S., Toropainen, E., Tavakoli, S., Kontturi, L-S., Lajunen, T., Tunik, S. P. & Urtti, A., 7 Apr 2020, In : RSC Advances. 10, 24, p. 14431-14440 10 p.

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Discovery of Membrane-Bound Pyrophosphatase Inhibitors Derived from an Isoxazole Fragment

Johansson, N. G., Turku, A., Vidilaseris, K., Dreano, L., Khattab, A., Ayuso Perez, D., Wilkinson, A., Zhang, Y., Tamminen, M., Grazhdankin, E., Kiriazis, A., Fishwick, C. W. G., Meri, S., Yli-Kauhaluoma, J., Goldman, A., Boije af Gennäs, G. & Xhaard, H., 9 Apr 2020, In : ACS Medicinal Chemistry Letters. 11, 4, p. 605-610 6 p.

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Drug Flux Across RPE Cell Models: The Hunt for An Appropriate Outer Blood-Retinal Barrier Model for Use in Early Drug Discovery

Hellinen, L., Hongisto, H., Ramsay, E., Kaarniranta, K., Vellonen, K-S., Skottman, H. & Ruponen, M., Feb 2020, In : Pharmaceutics. 12, 2, 13 p., 176.

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Endothermic and Exothermic Energy Transfer Made Equally Efficient for Triplet-Triplet Annihilation Upconversion

Isokuortti, J., Allu, S. R., Efimov, A., Vuorimaa-Laukkanen, E., Tkachenko, N. V., Vinogradov, S. A., Laaksonen, T. & Durandin, N. A., 2 Jan 2020, In : Journal of Physical Chemistry Letters. 11, 1, p. 318-324 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Extracellular vesicles provide a capsid-free vector for oncolytic adenoviral DNA delivery

Saari, H., Turunen, T., Lohmus, A., Turunen, M., Jalasvuori, M., Butcher, S. J., Yla-Herttuala, S., Viitala, T., Cerullo, V., Siljander, P. R. M. & Yliperttula, M., 1 Jan 2020, In : Journal of Extracellular Vesicles. 9, 1, 24 p., 1747206.

Research output: Contribution to journalArticleScientificpeer-review

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Fabrication and Characterization of Drug-Loaded Conductive Poly(glycerol sebacate)/Nanoparticle-Based Composite Patch for Myocardial Infarction Applications

Ezazi, N. Z., Ajdary, R., Correia, A., Mäkilä, E., Salonen, J., Kemell, M., Hirvonen, J., Rojas, O. J., Ruskoaho, H. J. & Santos, H. A., 12 Feb 2020, In : ACS Applied Materials & Interfaces. 12, 6, p. 6899-6909 11 p.

Research output: Contribution to journalArticleScientificpeer-review

First-year pharmacy students' prior knowledge correlates with study progress and reveals different dynamics of misconceptions

Södervik, I., Hanski, L. & Katajavuori, N., 2 Apr 2020, In : Pharmacy Education. 20, 1, p. 94-102 9 p.

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Formulation optimization and in vitro characterization of rifampicin and ceftriaxone dual drug loaded niosomes with high energy probe sonication technique

Khan, D. H., Bashir, S., Khan, M. I., Figueiredo, P., Santos, H. A. & Peltonen, L., Aug 2020, In : Journal of Drug Delivery Science and Technology. 58, 8 p., 101763.

Research output: Contribution to journalArticleScientificpeer-review

Gelatin Templated Polypeptide Co-crosslinked Hydrogel for Bone Regeneration

Qiao, Y., Liu, X., Zhou, X., Zhang, H., Zhang, W., Xiao, W., Pan, G., Cui, W., Santos, H. A. & Shi, Q., 8 Jan 2020, In : Advanced Healthcare Materials. 9, 1, 7 p., 1901239.

Research output: Contribution to journalArticleScientificpeer-review

Gene-hydrogel microenvironment regulates extracellular matrix metabolism balance in nucleus pulposus

Chen, W., Chen, H., Zheng, D., Zhang, H., Deng, L., Cui, W., Zhang, Y., Santos, H. A. & Shen, H., 8 Jan 2020, In : Advanced Science. 7, 1, 10 p., 1902099.

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Genetic lack of histamine upregulates dopamine neurotransmission and alters rotational behavior but not levodopa-induced dyskinesia in a mouse model of Parkinson’s disease

Koski, S. K., Leino, S., Panula, P., Rannanpää, S. & Salminen, O., 11 Jun 2020, In : Neuroscience Letters. 729, 6 p., 134932.

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Glial cell line-derived neurotrophic factor receptor REarranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo

Mahato, A. K., Kopra, J., Renko, J-M., Visnapuu, T., Korhonen, I., Pulkkinen, N., Bespalov, M. M., Domanskyi, A., Ronken, E., Piepponen, T. P., Voutilainen, M. H., Tuominen, R. K., Karelson, M., Sidorova, Y. A. & Saarma, M., Feb 2020, In : Movement Disorders. 35, 2, p. 245-255 11 p.

Research output: Contribution to journalArticleScientificpeer-review