Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications 1983 2019

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2019
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Acetalated Dextran Nanoparticles Loaded into an Injectable Alginate Cryogel for Combined Chemotherapy and Cancer Vaccination

Bauleth-Ramos, T., Ting-Yu Shih, T-Y. S., Shahbazi, M-A., Najibi, A. J., Mao, A. S., Liu, D., Granja, P., Santos, H. A., Sarmento, B. & Mooney, D. J., 7 Jun 2019, (Accepted/In press) In : Advanced Functional Materials.

Research output: Contribution to journalArticleScientificpeer-review

Acetylated nanocellulose for single-component bioinks and cell proliferation on 3D-printed scaffolds

Ajdary, R., Huan, S., Zanjanizadeh Ezazi, N., Xiang, W., Grande, R., Santos, H. A. & Rojas, O. J., 22 May 2019, (Accepted/In press) In : Biomacromolecules.

Research output: Contribution to journalArticleScientificpeer-review

A nebulin super-repeat panel reveals stronger actin binding toward the ends of the super-repeat region

Laitila, J., Lehtonen, J., Lehtokari, V-L., Sagath, L., Wallgren-Pettersson, C., Grönholm, M. & Pelin, K., Jan 2019, In : Muscle & Nerve. 59, 1, p. 116-121 6 p.

Research output: Contribution to journalArticleScientificpeer-review

An ethnobotanical survey and antifungal activity of Piper guineense used for the treatment of fungal infections in West-African traditional medicine

Mgbeahuruike, E. E., Holm, Y., Vuorela, H., Amandikwa, C. & Fyhrquist, P., 30 Jan 2019, In : Journal of Ethnopharmacology. 229, p. 157-166 10 p.

Research output: Contribution to journalArticleScientificpeer-review

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

Benetto Tiz, D., Skok, Ž., Durcik, M., Tomašič, T., Peterlin Mašič, L., Ilaš, J., Draskovits, G., Révész, T., Nyerges, Á., Pál, C., Cruz, C. D., Tammela, P. S. M., Žigon, D., Kikelj, D. & Zidar, N., 1 Apr 2019, In : European Journal of Medicinal Chemistry. 167, p. 269-290 22 p.

Research output: Contribution to journalArticleScientificpeer-review

A novel pathogenic UGT1A1 variant in a Sudanese child with type 1 Crigler-Najjar syndrome

Elfar, W., Järvinen, E., Weizhen, J. I., Mosorin, J., Sega, A. G., Iuga, A. C., Lobritto, S. J., Konstantino, M., Chan, A., Finel, M. & Lakhani, S. A., 1 Jan 2019, In : Drug Metabolism and Disposition. 47, 1, p. 45-48 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Antibacterial and antioxidative properties of different parts of garden rhubarb, blackcurrant, chokeberry and blue honeysuckle

Raudsepp, P., Koskar, J., Anton, D., Meremäe, K., Kapp, K., Laurson, P., Bleive, U., Kaldmäe, H., Roasto, M. & Püssa, T., 30 Mar 2019, In : Journal of the Science of Food and Agriculture. 99, 5, p. 2311-2320 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Automatic methodologies to perform loading and release assays of anticancer drugs from mesoporous silicon nanoparticles

Pereira, S., Passos, M., Correia, A., Mäkilä, E., Salonen, J., Araujo, A., Almeida Santos, H. & Saraiva, M. L., 1 May 2019, In : Talanta. 196, p. 277-283 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor

Fontana, F., Fusciello, M., Groeneveldt, C., Capasso, C., Chiaro, J., Feola, S., Liu, Z., Mäkilä, E., Salonen, J., Hirvonen, J., Cerullo, V. & Santos, H. A., 17 May 2019, In : ACS Nano. 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Capillary photoionization: interface for low flow rate liquid chromatography-mass spectrometry

Pöhö, P., Vaikkinen, A., Haapala, M., Kylli, P. & Kostiainen, R., 7 May 2019, In : Analyst. 144, 9, p. 2867-2871 5 p.

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Cartography of rhodopsin-like G protein-coupled receptors across vertebrate genomes

Rinne, M., Tanoli, Z-U-R., Khan, A. & Xhaard, H., 7 May 2019, In : Scientific Reports. 9, 16 p., 7058.

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Cell-Nanoparticle Interactions at (Sub)-Nanometer Resolution Analyzed by Electron Microscopy and Correlative Coherent Anti-Stokes Raman Scattering

Saarinen, J. K. S., Gütter, F., Lindman, M. M., Agopov, M., Fraser-Miller, S. J., Scherließ, R., Jokitalo, E., Almeida Santos, H., Peltonen, L., Isomäki, A. & Strachan, C. J., Apr 2019, In : Biotechnology Journal. 14, 4, 10 p., 1800413.

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Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells

Qi, S., Zhang, P., Ma, M., Yao, M., Wu, J., Mäkilä, E., Salonen, J., Ruskoaho, H., Xu, Y., Santos, H. A. & Zhang, H., 4 Jan 2019, In : Small. 15, 1, 13 p., 1804332.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy

Galli, E., Lindholm, P., Kontturi, L-S., Saarma, M., Urtti, A. & Yliperttula, M., 6 Mar 2019, In : Cell Transplantation.

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Chemical analysis using 3D printed glass microfluidics

Gal-Or, E., Gershoni, Y., Scotti, G., Nilsson, S. M. E., Saarinen, J. K. S., Jokinen, V. P., Strachan, C. J., Boije af Gennäs, P. G., Yli-Kauhaluoma, J. T. & Kotiaho, A. A. T., 7 Apr 2019, In : Analytical Methods. 11, 13, p. 1802-1810 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Chemical characteristics and stability of eucalyptus kraft pulps bleached with tertiary amine catalyzed hypochlorous acid

Afsahi, G., Rojalin, T. & Vuorinen, T., Feb 2019, In : Cellulose. 26, 3, p. 2047-2054 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Close-loop dynamic nanohybrids on collagen-ark with in situ gelling transformation capability for biomimetic stage-specific diabetic wound healing

Liu, Z., Li, Y., Li, W., Lian, W., Kemell, M., Hietala, S., Figueiredo, P., Li, L., Mäkilä, E., Ma, M., Salonen, J., Hirvonen, J. T., Liu, D., Zhang, H., Deng, X. & Santos, H. A., 1 Feb 2019, In : Materials Horizons. 6, 2, p. 385-393 9 p.

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Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses

Kohtala, H. S., Theilmann, W., Rosenholm, M., Penna, L., Karabulut, G., Uusitalo, S., Järventausta, K., Yli-Hankala, A., Yalcin, I., Matsui, N., Wigren, H-K. & Rantamäki, T., Jun 2019, In : Molecular Neurobiology. 56, 6, p. 4163-4174 12 p.

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Data on biosynthesis of BPAF glucuronide, enzyme kinetics of BPAF glucuronidation, and molecular modeling

Skledar, D. G., Trontelj, J., Troberg, J., Tomašič, T., Zega, A., Finel, M. & Mašič, L. P., Feb 2019, In : Data in Brief. 22, p. 977-986 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Dehydroabietylamine-Based Cellulose Nanofibril Films: A New Class of Sustainable Biomaterials for Highly Efficient, Broad-Spectrum Antimicrobial Effects

Hassan, G. A. M. S., Forsman, N., Wan, X., Keurulainen, L., Bimbo, L. M., Johansson, L-S., Sipari, N., Yli-Kauhaluoma, J. T., Zimmermann, R., Stehl, S., Werner, C., Saris, P. E. J., Österberg, M. & Moreira, V. M., 4 Mar 2019, In : ACS Sustainable Chemistry & Engineering. 7, 5, p. 5002-5009 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Design and evaluation of a multiplexed angular-scanning surface plasmon resonance system employing line-laser optics and CCD detection in combination with multi-ligand sensor chips

Lakayan, D., Tuppurainen, J., Suutari, T. E., van Iperen, D. J., Somsen, G. W. & Kool, J., 1 Mar 2019, In : Sensors and Actuators B: Chemical. 282, p. 243-250 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Determinants of Orexin Receptor Binding and Activation—A Molecular Dynamics Study

Karhu, L., Magarkar, A., Bunker, A. & Xhaard, H., 28 Mar 2019, In : Journal of Physical Chemistry B. 123, 12, p. 2609-2622 14 p.

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Dose-dependent effects of isoflurane on TrkB and GSK3β signaling: Importance of burst suppression pattern

Theilmann, W., Alitalo, O. A., Yorke, I. & Rantamäki, T. P. J., 16 Feb 2019, In : Neuroscience Letters. 694, p. 29-33 5 p.

Research output: Contribution to journalArticleScientificpeer-review

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Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease

Albert, K., Voutilainen, M. H., Domanskyi, A., Piepponen, T. P., Ahola, S., Tuominen, R. K., Richie, C., Harvey, B. K. & Airavaara, M., Mar 2019, In : Journal of Neuroscience Research. 97, 3, p. 346-361 16 p.

Research output: Contribution to journalArticleScientificpeer-review

DPD-inspired discovery of novel LsrK kinase inhibitors: an opportunity to fight antimicrobial resistance

Stotani, S., Gatta, V., Medarametla, P., Padmanaban, M., Karawajzyk, A., Giordanetto, F., Tammela, P., Laitinen, T., Poso, A., Tzalis, D. & Collina, S., 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2720-2737 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors

Diniz, C. R. A. F., Biojone, C., Joca, S. R. L., Rantamäki, T., Castren, E., Guimaraes, F. S. & Casarotto, P. C., 21 Feb 2019, In : PeerJ. 7, 21 p., 6493.

Research output: Contribution to journalArticleScientificpeer-review

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Efficient Fabrication of Polycaprolactone Scaffolds for Printing Hybrid Tissue-Engineered Constructs

Sodupe Ortega, E., Sanz-Garcia, A., Pernia-Espinoza, A. & Escobedo-Lucea, C., 2 Feb 2019, In : Materials. 12, 4, 18 p., 613.

Research output: Contribution to journalArticleScientificpeer-review

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Enantiospecific pharmacogenomics of fluvastatin

Hirvensalo, P., Tornio, A., Neuvonen, M., Kiander, W., Kidron, H., Paile-Hyvärinen, M., Tapaninen, T., Backman, J. T. & Niemi, M., 16 Apr 2019, In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticleScientificpeer-review

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Endocrine activities and adipogenic effects of bisphenol AF and its main metabolite

Skledar, D. G., Carino, A., Trontelj, J., Troberg, J., Distrutti, E., Marchiano, S., Tornasic, T., Zega, A., Finel, M., Fiorucci, S. & Maisic, L. P., Jan 2019, In : Chemosphere. 215, p. 870-880 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Environmentally-compatible alkyd paints stabilized by wood hemicelluloses

Mikkonen, K. S., Kirjoranta, S., Xu, C., Hemming, J., Pranovich, A., Bhattarai, M., Peltonen, L., Kilpeläinen, P., Maina, N., Tenkanen, M., Lehtonen, M. & Willför, S., 16 Mar 2019, In : Industrial Crops and Products. 133, p. 212-220

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Euryale Ferox Seed-inspired Super-lubricated Nanoparticles for Treatment of Osteoarthritis

Yan, Y., Sun, T., Zhang, H., Ji, X., Sun, Y., Zhao, X., Deng, L., Qi, J., Cui, W., Almeida Santos, H. & Zhang, H., 24 Jan 2019, In : Advanced Functional Materials. 29, 4, 14 p., 1807559.

Research output: Contribution to journalArticleScientificpeer-review

Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

Harloff-Helleberg, S., Fliervoet, L. A. L., Fano, M., Schmitt, M., Antopolski, M., Urtti, A. & Nielsen, H. M., 1 Jan 2019, In : Drug Delivery. 26, 1, p. 532-541 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Extracellular vesicles enhance the targeted delivery of immunogenic oncolytic adenovirus and paclitaxel in immunocompetent mice

Garofalo, M., Villa, A., Rizzi, N., Kuryk, L., Rinner, B., Cerullo, V., Yliperttula, M., Mazzaferro, V. & Ciana, P., 28 Jan 2019, In : Journal of Controlled Release. 294, p. 165-175 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Fluoroquinolone-related adverse events resulting in health service use and costs: A systematic review

Kuula, L. S. M., Viljemaa, K. M., Backman, J. T. & Blom, M., 26 Apr 2019, In : PLoS One. 14, 4, 17 p., 0216029.

Research output: Contribution to journalArticleScientificpeer-review

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Glucocorticoids promote breast cancer metastasis

Obradovic, M. M. S., Hamelin, B., Manevski, N., Couto, J. P., Sethi, A., Coissieux, M-M., Munst, S., Okamoto, R., Kohler, H., Schmidt, A. & Bentires-Alj, M., 28 Mar 2019, In : Nature. 567, 7749, p. 540-+ 21 p.

Research output: Contribution to journalArticleScientificpeer-review

Heavy metal content and health risk assessment of commonly patronized herbal medicinal preparations from the Kumasi metropolis of Ghana

Adusei-Mensah, F., Essumang, D. K., Agjei, R. O., Kauhanen, J., Tikkanen-Kaukanen, C. & Ekor, M., Apr 2019, In : Journal of environmental health science & engineering.

Research output: Contribution to journalArticleScientificpeer-review

Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice

Leggiero, E., Labruna, G., Iaffaldano, L., Lombardo, B., Greco, A., Fiorenza, D., Gramanzini, M., Montanaro, D., Baldi, A., Cerullo, V., Sacchetti, L. & Pastore, L., Apr 2019, In : Gene Therapy (Basingstoke). 26, 3-4, p. 121-130 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification and characterization of approved drugs and drug-like compounds as covalent Escherichia coli ClpP inhibitors

Sassetti, E., Cruz, CD., Tammela, P., Winterhalter, M., Augustyns, K., Gribbon, P. & Windshugel, B., 31 May 2019, In : International Journal of Molecular Sciences. 20, 11, p. 2686 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Image-Based Investigation: Biorelevant Solubility of α and γ Indomethacin

Štukelj, J., Svanbäck, S., Kristl, J., Strachan, C. J. & Yliruusi, J., 19 Mar 2019, In : Analytical Chemistry. 91, 6, p. 3997-4003 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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Immobilization of proteolytic enzymes on replica-molded thiol-ene micropillar reactors via thiol-gold interaction

Tähkä, S., Sarfraz, J., Urvas, L., Provenzani, R., Wiedmer, S. K., Peltonen, J., Jokinen, V. & Sikanen, T., Apr 2019, In : Analytical and Bioanalytical Chemistry. 411, 11, p. 2339–2349 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Impact of dibenzocyclooctadiene lignans from Schisandra chinensis on the redox status and activation of human innate immune system cells

Kortesoja, M., Karhu, E., Olafsdottir, E. S., Freysdottir, J. & Hanski, L., 1 Feb 2019, In : Free Radical Biology & Medicine. 131, p. 309-317 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Implementation of improved postoperative care decreases the mortality rate of operated mice after an abundant 6-hydroxydopamine lesion of nigrostriatal dopaminergic neurons

Koski, S. K., Leino, S., Rannanpää, S. K. & Salminen, O. S., 2019, (Accepted/In press) In : Scandinavian journal of laboratory animal science. 45, 1, 12 p.

Research output: Contribution to journalArticleScientificpeer-review