Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications 1983 2019

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2019
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A nebulin super-repeat panel reveals stronger actin binding toward the ends of the super-repeat region

Laitila, J., Lehtonen, J., Lehtokari, V-L., Sagath, L., Wallgren-Pettersson, C., Grönholm, M. & Pelin, K., Jan 2019, In : Muscle & Nerve. 59, 1, p. 116-121 6 p.

Research output: Contribution to journalArticleScientificpeer-review

An ethnobotanical survey and antifungal activity of Piper guineense used for the treatment of fungal infections in West-African traditional medicine

Mgbeahuruike, E. E., Holm, Y., Vuorela, H., Amandikwa, C. & Fyhrquist, P., 30 Jan 2019, In : Journal of Ethnopharmacology. 229, p. 157-166 10 p.

Research output: Contribution to journalArticleScientificpeer-review

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

Benetto Tiz, D., Skok, Ž., Durcik, M., Tomašič, T., Peterlin Mašič, L., Ilaš, J., Draskovits, G., Révész, T., Nyerges, Á., Pál, C., Cruz, CD., Tammela, P. S. M., Žigon, D., Kikelj, D. & Zidar, N., 10 Feb 2019, In : European Journal of Medicinal Chemistry. 167, p. 269-290 22 p.

Research output: Contribution to journalArticleScientificpeer-review

A novel pathogenic UGT1A1 variant in a Sudanese child with type 1 crigler-najjar syndrome

Elfar, W., Järvinen, E., Weizhen, J. I., Mosorin, J., Sega, A. G., Iuga, A. C., Lobritto, S. J., Konstantino, M., Chan, A., Finel, M. & Lakhani, S. A., 2019, In : Drug Metabolism and Disposition. 47, 1, p. 45-48 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Antibacterial and antioxidative properties of different parts of garden rhubarb, blackcurrant, chokeberry and blue honeysuckle

Raudsepp, P., Koskar, J., Anton, D., Meremäe, K., Kapp, K., Laurson, P., Bleive, U., Kaldmäe, H., Roasto, M. & Püssa, T., 30 Mar 2019, In : Journal of the Science of Food and Agriculture. 99, 5, p. 2311-2320 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Automatic methodologies to perform loading and release assays of anticancer drugs from mesoporous silicon nanoparticles

Pereira, S., Passos, M., Correia, A., Mäkilä, E., Salonen, J., Araujo, A., Almeida Santos, H. & Saraiva, M. L., 1 May 2019, In : Talanta. 196, p. 277-283 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Benzo[cd]azulen-3-ones with Built-in ortho/para-Quinone Methides

Kiriazis, A., Aumuller, I. B. & Yli-Kauhaluoma, J. T., 2019, (In preparation) In : European Journal of Organic Chemistry.

Research output: Contribution to journalArticleScientificpeer-review

Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells

Qi, S., Zhang, P., Ma, M., Yao, M., Wu, J., Mäkilä, E., Salonen, J., Ruskoaho, H., Xu, Y., Santos, H. A. & Zhang, H., 4 Jan 2019, In : Small. 15, 1, 13 p., 1804332.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy

Galli, E., Lindholm, P., Kontturi, L-S., Saarma, M., Urtti, A. & Yliperttula, M., 6 Mar 2019, In : Cell Transplantation.

Research output: Contribution to journalArticleScientificpeer-review

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Chemical analysis using 3D printed glass microfluidics

Gal-Or, E., Gershoni, Y., Scotti, G., Nilsson, S. M. E., Saarinen, J. K. S., Jokinen, V. P., Strachan, C. J., Boije af Gennäs, P. G., Yli-Kauhaluoma, J. T. & Kotiaho, A. A. T., 19 Feb 2019, (Accepted/In press) In : Analytical Methods.

Research output: Contribution to journalArticleScientificpeer-review

Close-loop dynamic nanohybrids on collagen-ark with in situ gelling transformation capability for biomimetic stage-specific diabetic wound healing

Liu, Z., Li, Y., Li, W., Lian, W., Kemell, M., Hietala, S., Figueiredo, P., Li, L., Mäkilä, E., Ma, M., Salonen, J., Hirvonen, J. T., Liu, D., Zhang, H., Deng, X. & Santos, H. A., 1 Feb 2019, In : Materials Horizons. 6, 2, p. 385-393 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Data on biosynthesis of BPAF glucuronide, enzyme kinetics of BPAF glucuronidation, and molecular modeling

Skledar, D. G., Trontelj, J., Troberg, J., Tomašič, T., Zega, A., Finel, M. & Mašič, L. P., 2019, In : Data in Brief.

Research output: Contribution to journalArticleScientificpeer-review

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Dehydroabietylamine-based Cellulose Nanofibril Films: A new Class of Sustainable Biomaterials for Highly Efficient, Broad-Spectrum Antimicrobial Effect

Hassan, G. A. M. S., Forsman, N. M., Wan, X., Keurulainen, L. M., Bimbo, L. M., Johansson, L-S., Sipari, N. H., Yli-Kauhaluoma, J. T., Zimmermann, R., Stehl, S., Werner, C., Saris, P. E. J., Österberg, M. & Moreira, V. M., 4 Mar 2019, In : ACS Sustainable Chemistry & Engineering. 7, 5, p. 5002-5009 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Design and evaluation of a multiplexed angular-scanning surface plasmon resonance system employing line-laser optics and CCD detection in combination with multi-ligand sensor chips

Lakayan, D., Tuppurainen, J., Suutari, T. E., van Iperen, D. J., Somsen, G. W. & Kool, J., 1 Mar 2019, In : Sensors and Actuators B: Chemical. 282, p. 243-250 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Dose-dependent effects of isoflurane on TrkB and GSK3β signaling: Importance of burst suppression pattern

Theilmann, W., Alitalo, O. A., Yorke, I. & Rantamäki, T. P. J., 16 Feb 2019, In : Neuroscience Letters. 694, p. 29-33 5 p.

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Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease

Albert, K., Voutilainen, M. H., Domanskyi, A., Piepponen, T. P., Ahola, S., Tuominen, R. K., Richie, C., Harvey, B. K. & Airavaara, M., Mar 2019, In : Journal of Neuroscience Research. 97, 3, p. 346-361 16 p.

Research output: Contribution to journalArticleScientificpeer-review

DPD-inspired discovery of novel LsrK kinase inhibitors: an opportunity to fight antimicrobial resistance

Stotani, S., Gatta, V., Medarametla, P., Padmanaban, M., Karawajzyk, A., Giordanetto, F., Tammela, P. S. M., Laitinen, T., Poso, A., Tzalis, D. & Collina, S., 20 Feb 2019, In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticleScientificpeer-review

Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors

Diniz, C. R. A. F., Biojone, C., Joca, S. R. L., Rantamäki, T., Castren, E., Guimaraes, F. S. & Casarotto, P. C., 21 Feb 2019, In : PeerJ. 7, 21 p., 6493.

Research output: Contribution to journalArticleScientificpeer-review

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Endocrine activities and adipogenic effects of bisphenol AF and its main metabolite

Skledar, D. G., Carino, A., Trontelj, J., Troberg, J., Distrutti, E., Marchiano, S., Tornasic, T., Zega, A., Finel, M., Fiorucci, S. & Maisic, L. P., Jan 2019, In : Chemosphere. 215, p. 870-880 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Environmentally-compatible alkyd paints stabilized by wood hemicelluloses

Mikkonen, K. S., Kirjoranta, S., Xu, C., Hemming, J., Pranovich, A., Bhattarai, M., Peltonen, L., Kilpeläinen, P., Maina, N., Tenkanen, M., Lehtonen, M. & Willför, S., 16 Mar 2019, In : Industrial Crops and Products. 133, p. 212-220

Research output: Contribution to journalArticleScientificpeer-review

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Euryale Ferox Seed-inspired Super-lubricated Nanoparticles for Treatment of Osteoarthritis

Yan, Y., Sun, T., Zhang, H., Ji, X., Sun, Y., Zhao, X., Deng, L., Qi, J., Cui, W., Almeida Santos, H. & Zhang, H., 24 Jan 2019, In : Advanced Functional Materials. 29, 4, 14 p., 1807559.

Research output: Contribution to journalArticleScientificpeer-review

Extracellular vesicles enhance the targeted delivery of immunogenic oncolytic adenovirus and paclitaxel in immunocompetent mice

Garofalo, M., Villa, A., Rizzi, N., Kuryk, L., Rinner, B., Cerullo, V., Yliperttula, M., Mazzaferro, V. & Ciana, P., 28 Jan 2019, In : Journal of Controlled Release. 294, p. 165-175 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Immobilization of proteolytic enzymes on replica-molded thiol-ene micropillar reactors via thiol-gold interaction

Tähkä, S., Sarfraz, J., Urvas, L., Provenzani, R., Wiedmer, S. K., Peltonen, J., Jokinen, V. & Sikanen, T. M., 2019, (Accepted/In press) In : Analytical and Bioanalytical Chemistry.

Research output: Contribution to journalArticleScientificpeer-review

Impact of dibenzocyclooctadiene lignans from Schisandra chinensis on the redox status and activation of human innate immune system cells

Kortesoja, M., Karhu, E., Olafsdottir, E. S., Freysdottir, J. & Hanski, L., 1 Feb 2019, In : Free Radical Biology & Medicine. 131, p. 309-317 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Implementation of improved postoperative care decreases the mortality rate of operated mice after an abundant 6-hydroxydopamine lesion of nigrostriatal dopaminergic neurons

Koski, S. K., Leino, S., Rannanpää, S. K. & Salminen, O. S., 2019, (Accepted/In press) In : Scandinavian journal of laboratory animal science. 45, 1, 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Inhibition of Hepatitis C replication by targeting the molecular chaperone Hsp90 - synthesis and biological evaluation of 4,5,6,7-tetrahydrobenzo[1,2-d]thiazole derivatives

Lillsunde, K-E. M., Tomašič, T., Schult, P., Lohmann, V., Kikelj, D. & Tammela, P., 5 Feb 2019, In : ChemMedChem : chemistry enabling drug discovery.. 14, 3, p. 334-342 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Inhibition of UGT1A1 by natural and synthetic flavonoids

Liu, X-Y., Lv, X., Wang, P., Ai, C-Z., Zhou, Q-H., Finel, M., Fan, B., Cao, Y-F., Tang, H. & Ge, G-B., 1 Apr 2019, In : International Journal of Biological Macromolecules. 126, p. 653 – 661

Research output: Contribution to journalArticleScientificpeer-review

Kohtaavatko saatavuus ja hyödyt? Korvausjärjestelmään hyväksytyt uudet syöpälääkkeet

Koskinen, H., Juntunen, L., Junttila, T. & Kurko, T., 2019, In : Suomen lääkärilehti. 74, 6, p. 327-330 4 p.

Research output: Contribution to journalArticleProfessional

Laser-Activatable CuS Nanodots to Treat Multidrug-Resistant Bacteria and Release Copper Ion to Accelerate Healing of Infected Chronic Nonhealing Wounds

Qiao, Y., Ping, Y., Zhang, H., Zhou, B., Liu, F., Yu, Y., Xie, T., Li, W., Zhong, D., Zhang, Y., Yao, K., Almeida Santos, H. & Zhou, M., 30 Jan 2019, In : ACS Applied Materials & Interfaces. 11, 4, p. 3809–3822 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

Felszeghy, S., Viiri, J., Paterno, J. J., Hyttinen, J. M. T., Koskela, A., Chen, M., Leinonen, H., Tanila, H., Kivinen, N., Koistinen, A., Toropainen, E., Amadio, M., Smedowski, A., Reinisalo, M., Winiarczyk, M., Mackiewicz, J., Mutikainen, M., Ruotsalainen, A-K., Kettunen, M., Jokivarsi, K. & 16 othersSinha, D., Kinnunen, K., Petrovski, G., Blasiak, J., Bjorkoy, G., Koskelainen, A., Skottman, H., Urtti, A., Salminen, A., Kannan, R., Ferrington, D. A., Xu, H., Levonen, A-L., Tavi, P., Kauppinen, A. & Kaarniranta, K., Jan 2019, In : Redox biology. 20, p. 1-12 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Neurotrophin receptor Ntrk2b function in the maintenance of dopamine and serotonin neurons in zebrafish

Sahu, M. P., Pazos-Boubeta, Y., Pajanoja, C., Rozov, S., Panula, P. & Castren, E., 14 Feb 2019, In : Scientific Reports. 9, 13 p., 2036.

Research output: Contribution to journalArticleScientificpeer-review

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ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol

Koponen, A., Arora, A., Takahashi, K., Kentala, H., Kivela, A. M., Jaaskelainen, E., Peranen, J., Somerharju, P., Ikonen, E., Viitala, T. & Olkkonen, V. M., Mar 2019, In : Biochimie. 158, p. 90-101 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Overcoming the Pitfalls of Cytochrome P450 Immobilization Through the Use of Fusogenic Liposomes

Kiiski, I. M. A., Pihlaja, T. L. M., Urvas, L. M., Wiedmer, S. K., Witos, J. M., Jokinen, V. P. & Sikanen, T. M., 11 Jan 2019, In : Advanced Biosystems. 3, 1, 6 p., 1800245.

Research output: Contribution to journalArticleScientificpeer-review

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Porous silicon as a platform for radiation theranostics together with a novel RIB based radiolanthanoid

Jakobsson, E. H. U., Mäkilä, E., Airaksinen, A., Alanen, O. S., Etile, A., Köster, U., Ranjan, S., Salonen, J., Almeida Santos, H. & Helariutta, A. M. K., 7 Feb 2019, In : Contrast media & molecular imaging. 2019, 9 p., 3728563.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Process optimization of ecological probe sonication technique for production of rifampicin loaded niosomes

Khan, D. H., Bashir, S., Figueiredo, P. I., Almeida Santos, H., Khan, M. I. & Peltonen, L. J., Apr 2019, In : Journal of Drug Delivery Science and Technology. 50, p. 27-33 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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Quantifying the interactions between biomimetic biomaterials - collagen I, collagen IV, laminin 521 and cellulose nanofibrils - by colloidal probe microscopy

Nugroho, R. W. N., Harjumäki, R., Zhang, X., Lou, Y-R., Yliperttula, M., Valle-Delgado, J. J. & Österberg, M., 1 Jan 2019, In : Colloids and Surfaces B: Biointerfaces. 173, p. 571-580 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Radiolabeled Molecular Imaging Probes for the in Vivo Evaluation of Cellulose Nanocrystals for Biomedical Applications

Imlimthan, S., Otaru, S., Keinänen, O., Correia, A., Lintinen, K., Almeida Santos, H., Airaksinen, A., Kostiainen, M. & Sarparanta, M., Feb 2019, In : Biomacromolecules. 20, 2, p. 674–683 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Self-healing and injectable hydrogel for matching skin flap regeneration

Mao, X., Cheng, R., Zhang, H., Bae, J., Cheng, L., Zhang, L., Deng, L., Cui, W., Zhang, Y., Almeida Santos, H. & Sun, X., 6 Feb 2019, In : Advanced Science. 6, 3, p. 1801555 10 p., 1801555.

Research output: Contribution to journalArticleScientificpeer-review

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Strategies for improving medication safety in hospitals: Evolution of clinical pharmacy services

Lotta, S., Kirsi, A., Kirsi, K., Anna-Riia, H., Lasse, L., Outi, L-R., Raisa, L., Kerstin, C. & Marja, A., 16 Mar 2019, In : Research in Social and Administrative Pharmacy.

Research output: Contribution to journalArticleScientificpeer-review

Striving for benefits of sustainability from the interactivity of quality and innovation

Anttila, J. & Jussila, K. P., 1 Mar 2019, In : Journal of Cleaner Production. 212, p. 409-419 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Submission of Rifaximin to Different Techniques: Characterization, Solubility Study, and Microbiological Evaluation

Kogawa, A. C., Peltonen, L., Antonio, S. G. & Nunes Salgado, H. R., Apr 2019, In : AAPS PharmSciTech. 20, 3, 13 p., 125.

Research output: Contribution to journalArticleScientificpeer-review

Tissue-specific study across the stem reveals the chemistry and transcriptome dynamics of birch bark.

Alonso Serra, J. A., Safronov, O., Lim, K-J., Fraser-Miller, S., Blokhina, O. B., Campilho, A., Chong, S-L., Fagerstedt, K. V., Haavikko, R. H., Helariutta, Y. E., Immanen, J. J. M., Kangasjärvi, J. S., Kauppila, T. J., Lehtonen, M., Ragni, L., Rajaraman, S., Riikka-Marjaana, R., Safdari, P., Tenkanen, T. M., Yli-Kauhaluoma, J. T. & 4 othersTeeri, T. H., Strachan, C. J., Nieminen, K. & Salojärvi, J. T., 6 Feb 2019, In : New Phytologist.

Research output: Contribution to journalArticleScientificpeer-review

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Open Access