Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications 1983 2019

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2019

Image-Based Investigation: Biorelevant Solubility of α and γ Indomethacin

Štukelj, J., Svanbäck, S., Kristl, J., Strachan, C. J. & Yliruusi, J., 19 Mar 2019, In : Analytical Chemistry. 91, 6, p. 3997-4003 7 p.

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Immobilization of proteolytic enzymes on replica-molded thiol-ene micropillar reactors via thiol-gold interaction

Tähkä, S., Sarfraz, J., Urvas, L., Provenzani, R., Wiedmer, S. K., Peltonen, J., Jokinen, V. & Sikanen, T., Apr 2019, In : Analytical and Bioanalytical Chemistry. 411, 11, p. 2339–2349 11 p.

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Impact of dibenzocyclooctadiene lignans from Schisandra chinensis on the redox status and activation of human innate immune system cells

Kortesoja, M., Karhu, E., Olafsdottir, E. S., Freysdottir, J. & Hanski, L., 1 Feb 2019, In : Free Radical Biology & Medicine. 131, p. 309-317 9 p.

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Implementation of improved postoperative care decreases the mortality rate of operated mice after an abundant 6-hydroxydopamine lesion of nigrostriatal dopaminergic neurons

Koski, S. K., Leino, S., Rannanpää, S. K. & Salminen, O. S., 2019, (Accepted/In press) In : Scandinavian journal of laboratory animal science. 45, 1, 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Improving Group Work Practices in Teaching Life Sciences: Trialogical Learning

Tammeorg, P., Mykkänen, A., Rantamäki, T., Lakkala, M. & Muukkonen, H., Jun 2019, In : Research in Science Education. 49, 3, p. 809-828 20 p.

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Influence of Melanin Characteristics on Drug Binding Properties

Jakubiak, P., Lack, F., Thün, J., Urtti, A. & Alvarez-Sanchez, R., Jun 2019, In : Molecular Pharmaceutics. 16, 6, p. 2549-2556 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Influence of strategic planning on product marketing and health service orientation of community pharmacies-A national survey in Finland

Jokinen, L., Puumalainen, I. & Airaksinen, M., May 2019, In : Health Policy. 123, 5, p. 462-467 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Inhibition of Hepatitis C replication by targeting the molecular chaperone Hsp90 - synthesis and biological evaluation of 4,5,6,7-tetrahydrobenzo[1,2-d]thiazole derivatives

Lillsunde, K-E. M., Tomašič, T., Schult, P., Lohmann, V., Kikelj, D. & Tammela, P., 5 Feb 2019, In : ChemMedChem : chemistry enabling drug discovery.. 14, 3, p. 334-342 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Inhibition of let-7c Regulates Cardiac Regeneration after Cryoinjury in Adult Zebrafish

Narumanchi, S., Kalervo, K., Perttunen, S., Wang, H., Immonen, K., Kosonen, R., Laine, M., Ruskoaho, H. J., Tikkanen, I. T., Lakkisto, P. J. & Paavola, J., 4 Apr 2019, In : Journal of Cardiovascular Development and Disease. 6, 2

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Inhibition of UGT1A1 by natural and synthetic flavonoids

Liu, X-Y., Lv, X., Wang, P., Ai, C-Z., Zhou, Q-H., Finel, M., Fan, B., Cao, Y-F., Tang, H. & Ge, G-B., 1 Apr 2019, In : International Journal of Biological Macromolecules. 126, p. 653 – 661 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Inter-rater reliability of medication error classification in a voluntary patient safety incident reporting system HaiPro in Finland

Holmström, A-R., Järvinen, R., Laaksonen, R., Keistinen, T., Doupi, P. & Airaksinen, M., Jul 2019, In : Research in Social and Administrative Pharmacy. 15, 7, p. 864-872 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Ketamine-induced regulation of TrkB-GSK3β signaling is accompanied by slow EEG oscillations and sedation but is independent of hydroxynorketamine metabolites

Kohtala, H. S., Theilmann, W., Rosenholm, M. P., Müller, H. K., Kiuru, P. S., Wegener, G., Yli-Kauhaluoma, J. T. & Rantamäki, T. P. J., 25 Jun 2019, In : Neuropharmacology. 157, 9 p., 107684.

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Kohtaavatko saatavuus ja hyödyt? Korvausjärjestelmään hyväksytyt uudet syöpälääkkeet

Koskinen, H., Juntunen, L., Junttila, T. & Kurko, T., 2019, In : Suomen lääkärilehti. 74, 6, p. 327-330 4 p.

Research output: Contribution to journalArticleProfessional

Laser-Activatable CuS Nanodots to Treat Multidrug-Resistant Bacteria and Release Copper Ion to Accelerate Healing of Infected Chronic Nonhealing Wounds

Qiao, Y., Ping, Y., Zhang, H., Zhou, B., Liu, F., Yu, Y., Xie, T., Li, W., Zhong, D., Zhang, Y., Yao, K., Almeida Santos, H. & Zhou, M., 30 Jan 2019, In : ACS Applied Materials & Interfaces. 11, 4, p. 3809–3822 14 p.

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Levels of glial cell line-derived neurotrophic factor are decreased, but fibroblast growth factor 2 and cerebral dopamine neurotrophic factor are increased in the hippocampus in parkinson's disease

Virachit, S., Mathews, K. J., Cottam, V., Werry, E., Galli, E., Rappou, E., Lindholm, P., Saarma, M., Halliday, G. M., Shannon Weickert, C. & Double, K. L., 29 Apr 2019, In : Brain Pathology.

Research output: Contribution to journalArticleScientificpeer-review

Light-Triggered Cellular Delivery of Oligonucleotides

Kontturi, L-S., van den Dikkenberg, J., Urtti, A., Hennink, W. E. & Mastrobattista, E., Feb 2019, In : Pharmaceutics. 11, 2, 16 p., 90.

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Lipid-Polymer Hybrid Nanoparticles for Controlled Delivery of Hydrophilic and Lipophilic Doxorubicin for Breast Cancer Therapy

Tahir, N., Madni, A., Correia, A., Rehman, M., Balasubramanian, V., Khan, M. M. & Santos, H. A., 5 Jul 2019, In : International Journal of Nanomedicine. 14, p. 4961-4974 14 p.

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Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

Felszeghy, S., Viiri, J., Paterno, J. J., Hyttinen, J. M. T., Koskela, A., Chen, M., Leinonen, H., Tanila, H., Kivinen, N., Koistinen, A., Toropainen, E., Amadio, M., Smedowski, A., Reinisalo, M., Winiarczyk, M., Mackiewicz, J., Mutikainen, M., Ruotsalainen, A-K., Kettunen, M., Jokivarsi, K. & 16 othersSinha, D., Kinnunen, K., Petrovski, G., Blasiak, J., Bjorkoy, G., Koskelainen, A., Skottman, H., Urtti, A., Salminen, A., Kannan, R., Ferrington, D. A., Xu, H., Levonen, A-L., Tavi, P., Kauppinen, A. & Kaarniranta, K., Jan 2019, In : Redox biology. 20, p. 1-12 12 p.

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Metabolic signature of extracellular vesicles depends on the cell culture conditions

Palviainen, M., Saari, H., Kärkkäinen, O., Pekkinen, J., Auriola, S., Yliperttula, M., Puhka, M., Hanhineva, K. & Siljander, P. R-M., 1 Jan 2019, In : Journal of Extracellular Vesicles. 8, 1, 12 p., 1596669.

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Metabolism of Scoparone in Experimental Animals and Humans

Juvonen, R. O., Novak, F., Emmanouilidou, E., Auriola, S., Timonen, J., Heikkinen, A. T., Küblbeck, J., Finel, M. & Raunio, H., Apr 2019, In : Planta Medica. 85, 6, p. 453-464 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Neuronal activation stimulates cytomegalovirus promoter-driven transgene expression

Bäck, S., Dossat, A., Parkkinen, I., Koivula, P., Airavaara, M., Richie, C. T., Chen, Y-H., Wang, Y. & Harvey, B. K., 2019, In : Molecular therapy-Methods & clinical development.

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Neurotrophin receptor Ntrk2b function in the maintenance of dopamine and serotonin neurons in zebrafish

Sahu, M. P., Pazos-Boubeta, Y., Pajanoja, C., Rozov, S., Panula, P. & Castren, E., 14 Feb 2019, In : Scientific Reports. 9, 13 p., 2036.

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New N-phenyl-4,5-dibromopyrrolamides as DNA gyrase B inhibitors

Zidar, N., Macut, H., Tomašič, T., Peterlin Mašič, L., Ilaš, J., Zega, A., Tammela, P. & Kikelj, D., 19 May 2019, (Accepted/In press) In : MedChemComm.

Research output: Contribution to journalArticleScientificpeer-review

Optimization of Early Steps in Oncolytic Adenovirus ONCOS-401 Production in T-175 and HYPERFlasks

Kuryk, L., Moller, A-S. W., Vuolanto, A., Pesonen, S., Garofalo, M., Cerullo, V. & Jaderberg, M., 1 Feb 2019, In : International Journal of Molecular Sciences. 20, 3, 15 p., 621.

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ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol

Koponen, A., Arora, A., Takahashi, K., Kentala, H., Kivela, A. M., Jaaskelainen, E., Peranen, J., Somerharju, P., Ikonen, E., Viitala, T. & Olkkonen, V. M., Mar 2019, In : Biochimie. 158, p. 90-101 12 p.

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Overcoming the Pitfalls of Cytochrome P450 Immobilization Through the Use of Fusogenic Liposomes

Kiiski, I. M. A., Pihlaja, T. L. M., Urvas, L. M., Wiedmer, S. K., Witos, J. M., Jokinen, V. P. & Sikanen, T. M., 11 Jan 2019, In : Advanced Biosystems. 3, 1, 6 p., 1800245.

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Photothermal-responsive nanosized hybrid polymersome as versatile therapeutics codelivery nanovehicle for effective tumor suppression

Zhang, H., Cui, W., Qu, X., Wu, H., Qu, L., Zhang, X., Mäkilä, E., Salonen, J., Zhu, Y., Yang, Z., Chen, D., Santos, H. A., Hai, M. & Weitz, D. A., 16 Apr 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 16, p. 7744-7749 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Porous Silicon as a Platform for Radiation Theranostics Together with a Novel RIB-Based Radiolanthanoid

Jakobsson, U., Mäkilä, E., Airaksinen, A. J., Alanen, O., Etile, A., Köster, U., Ranjan, S., Salonen, J., Santos, H. A. & Helariutta, K., 12 Mar 2019, In : Contrast Media & Molecular Imaging. 2019, 9 p., 3728563.

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Practical realization of a sub-λ/2 acoustic jet

Canle, D. V., Kekkonen, T., Mäkinen, J., Puranen, T., Nieminen, H. J., Kuronen, A., Franssila, S., Kotiaho, T., Salmi, A. & Haeggstrom, E., 26 Mar 2019, In : Scientific Reports. 9, 6 p., 5189.

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Preparation and characterization of dentin phosphophoryn-derived peptide-functionalized lignin nanoparticles for enhanced cellular uptake

Figueiredo, P. I., Sipponen, M. H., Lintinen, K., Rebelo Correia, A. M., Kiriazis, A., Yli-Kauhaluoma, J. T., Österberg, M., George, A., Hirvonen, J. T., Kostiainen, M. A. & Almeida Santos, H., 14 Jun 2019, In : Small. 15, 24, 14 p., 1901427.

Research output: Contribution to journalArticleScientificpeer-review

Process optimization of ecological probe sonication technique for production of rifampicin loaded niosomes

Khan, D. H., Bashir, S., Figueiredo, P., Santos, H. A., Khan, M. I. & Peltonen, L., Apr 2019, In : Journal of Drug Delivery Science and Technology. 50, p. 27-33 7 p.

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Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo

Mäki-Opas, I., Hämäläinen, M., Moilanen, L., Haavikko, R. H., Ahonen, T. J., Alakurtti, S., Moreira, V. M., Muraki, K., Yli-Kauhaluoma, J. T. & Moilanen, E., 19 Jun 2019, In : ACS chemical neuroscience. 10, 6, p. 2848-2857 10 p.

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Quantified forces between HepG2 hepatocarcinoma and WA07 pluripotent stem cells with natural biomaterials correlate with in vitro cell behavior

Harjumaki, R., Nugroho, R. W. N., Zhang, X., Lou, Y-R., Yliperttula, M., Valle-Delgado, J. J. & Österberg, M., 14 May 2019, In : Scientific Reports. 9, 14 p., 7354.

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Quantifying the interactions between biomimetic biomaterials - collagen I, collagen IV, laminin 521 and cellulose nanofibrils - by colloidal probe microscopy

Nugroho, R. W. N., Harjumäki, R., Zhang, X., Lou, Y-R., Yliperttula, M., Valle-Delgado, J. J. & Österberg, M., 1 Jan 2019, In : Colloids and Surfaces B: Biointerfaces. 173, p. 571-580 10 p.

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Radiolabeled Molecular Imaging Probes for the in Vivo Evaluation of Cellulose Nanocrystals for Biomedical Applications

Imlimthan, S., Otaru, S., Keinänen, O., Correia, A., Lintinen, K., Almeida Santos, H., Airaksinen, A., Kostiainen, M. & Sarparanta, M., Feb 2019, In : Biomacromolecules. 20, 2, p. 674–683 10 p.

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Self-healing and injectable hydrogel for matching skin flap regeneration

Mao, X., Cheng, R., Zhang, H., Bae, J., Cheng, L., Zhang, L., Deng, L., Cui, W., Zhang, Y., Almeida Santos, H. & Sun, X., 6 Feb 2019, In : Advanced Science. 6, 3, 10 p., 1801555.

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Simple 3D printed stainless steel microreactors for online mass spectrometric analysis

Scotti, G., Nilsson, S. M. E., Matilainen, V-P., Haapala, M., Boije af Gennäs, G., Yli-Kauhaluoma, J., Salminen, A. & Kotiaho, T., 2 Jul 2019, In : Heliyon. 5, 7, 7 p., e02002.

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Strategies for improving medication safety in hospitals: Evolution of clinical pharmacy services

Lotta, S., Kirsi, A., Kirsi, K., Anna-Riia, H., Lasse, L., Outi, L-R., Raisa, L., Kerstin, C. & Marja, A., 16 Mar 2019, In : Research in Social and Administrative Pharmacy.

Research output: Contribution to journalArticleScientificpeer-review

Striving for benefits of sustainability from the interactivity of quality and innovation

Anttila, J. & Jussila, K. P., 1 Mar 2019, In : Journal of Cleaner Production. 212, p. 409-419 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Submission of Rifaximin to Different Techniques: Characterization, Solubility Study, and Microbiological Evaluation

Kogawa, A. C., Peltonen, L., Antonio, S. G. & Nunes Salgado, H. R., Apr 2019, In : AAPS PharmSciTech. 20, 3, 13 p., 125.

Research output: Contribution to journalArticleScientificpeer-review

Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor

Cortes, E., Lachowski, D., Rice, A., Thorpe, S. D., Robinson, B., Yeldag, G., Lee, D. A., Ghemtio Wafo, L. A., Rombouts, K. & E. del Río Hernández, A., 18 Apr 2019, In : Oncogene. 38, 16, p. 2910–2922 13 p.

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Targeted Reinforcement of Macrophage Reprogramming Toward M2 Polarization by IL-4-Loaded Hyaluronic Acid Particles (vol 1, pg 18444, 2018)

Shahbazi, M-A., Mahsa Sedighi, M. S., Bauleth-Ramos, T., Krishna Kant, K., Correia, A., Poursina, N., Sarmento, B., Hirvonen, J. T. & Almeida Santos, H., 28 Apr 2019, In : ACS Omega. 4, 3, p. 5931-5931 1 p.

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The viral protein corona directs viral pathogenesis and amyloid aggregation

Ezzat, K., Pernemalm, M., Palsson, S., Roberts, T. C., Järver, P., Dondalska, A., Bestas, B., Sobkowiak, M. J., Levänen, B., Sköld, M., Thompson, E. A., Saher, O., Kari, O. K., Lajunen, T., Ekstrom, E. S., Nilsson, C., Ishchenko, Y., Malm, T., Wood, M. J. A., Power, U. F. & 6 othersMasich, S., Linden, A., Sandberg, J. K., Lehtiö, J., Spetz, A-L. & EL Andaloussi, S., 27 May 2019, In : Nature Communications. 10, 16 p., 2331.

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The Water Extract of Juniperus communis L. Induces Cell Death and Sensitizes Cancer Cells to Cytostatic Drugs through p53 and PI3K/Akt Pathways

Raasmaja, A., Stenius, U. & Ghalali, A., 1 May 2019, In : International Journal of Molecular Sciences. 20, 9, 9 p., 2054.

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TiO2 Photocatalyzed Oxidation of Drugs Studied by Laser Ablation Electrospray Ionization Mass Spectrometry

van Geenen, F. A. M. G., Franssen, M. C. R., Miikkulainen, V., Ritala, M., Zuilhof, H., Kostiainen, R. & Nielen, M. W. F., Apr 2019, In : Journal of the American Society for Mass Spectrometry. 30, 4, p. 639-646 8 p.

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