Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications 1970 2019

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2016

Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei

Lahti, L., Haugas, M., Tikker, L., Airavaara, M., Voutilainen, M., Anttila, J., Kumar, S., Inkinen, C., Salminen, M. & Partanen, J., 1 Feb 2016, In : Development. 143, 3, p. 516-529 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Discovery of bentzothiazole scaffold-based DNA gyrase B inhibitors

Gjorgjieva, M., Tomašič, T., Barančokova, M., Katsamakas, S., Ilaš, J., Tammela, P., Peterlin Mašič, L. & Kikelj, D., Oct 2016, In : Journal of Medicinal Chemistry. 59, 19, p. 8941-8954 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses

Varghese, F. S., Kaukinen, P., Glasker, S., Bespalov, M., Hanski, L., Wennerberg, K., Kummerer, B. M. & Ahola, T., Feb 2016, In : Antiviral Research. 126, p. 117-124 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Drug Distribution to Retinal Pigment Epithelium: Studies on Melanin Binding, Cellular Kinetics, and Single Photon Emission Computed Tomography/Computed Tomography Imaging

Rimpelä, A-K., Schmitt, M., Latonen, S., Hagström, M., Antopolsky, M., Manzanares, J. A., Kidron, H. & Urtti, A., Sep 2016, In : Molecular Pharmaceutics. 13, 9, p. 2977-2986 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Drug permeation and cellular interaction of amino acid-coated drug combination powders for pulmonary delivery

Vartiainen, V., Bimbo, L. M., Hirvonen, J., Kauppinen, E. I. & Raula, J., 17 May 2016, In : International Journal of Pharmaceutics. 504, 1-2, p. 89-97 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Dual chitosan/albumin-coated alginate/dextran sulfate nanoparticles for enhanced oral delivery of insulin

Lopes, M., Shrestha, N., Correia, A., Shahbazi, M-A., Sarmento, B., Hirvonen, J., Veiga, F., Seica, R., Ribeiro, A. & Santos, H. A., 28 Jun 2016, In : Journal of Controlled Release. 232, p. 29-41 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Editorial, Special issue BBBB

Sandler, N. & Peltonen, L. J., 2016, In : European Journal of Pharmaceutical Sciences. 95, p. 1 1 p.

Research output: Contribution to journalArticleScientific

Editorial: Medicinal product, medical device or combination product – challenges and opportunities

Juppo, A. & Rosenqvist, K., 2016, In : Journal of Pharmaceutical Analytics and Insights. 1, 3, 1 p., e103.

Research output: Contribution to journalArticleScientific

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Editorial for the Special Issue "Scandinavia"

Peltonen, L. J., 2016, In : Journal of Drug Delivery Science and Technology. 34, p. A1 1 p.

Research output: Contribution to journalArticleScientific

Effect of chain architecture on the phase transition of star and cyclic poly(N-isopropylacrylamide) in water

Xue, N., Qiu, X-P., Chen, Y., Satoh, T., Kakuchi, T. & Winnik, F. M., 15 Oct 2016, In : Journal of Polymer Science. Part B, Polymer Physics. 54, 20, p. 2059-2068 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of vasoactive peptides in Tetrahymena: chemotactic activities of adrenomedullin, proadrenomedullin N-terminal 20 peptide (PAMP) and calcitonin gene-related peptide (CGRP)

Kohidai, L., Toth, K., Samotik, P., Ranganathan, K., Lang, O., Toth, M. & Ruskoaho, H., Jan 2016, In : Molecular and Cellular Biochemistry. 411, 1-2, p. 271-280 10 p.

Research output: Contribution to journalArticleScientificpeer-review

ELIMINATION OF EXTRACELLULAR DOPAMINE IN THE MEDIAL PREFRONTAL CORTEX OF CONSCIOUS MICE ANALYZED USING SELECTIVE ENZYME AND UPTAKE INHIBITORS

Tammimaki, A., Aonurm-Helm, A., Kaenmaki, M. & Mannisto, P. T., Apr 2016, In : Journal of Physiology and Pharmacology. 67, 2, p. 301-309 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Enhanced Photoluminescence in Acetylene-Treated ZnO Nanorods

Jäppinen, L., Jalkanen, T., Sieber, B., Addad, A., Heinonen, M., Kukk, E., Radevici, I., Paturi, P., Peurla, M., Shahbazi, M-A., Santos, H. A., Boukherroub, R., Santos, H., Lastusaari, M. & Salonen, J., 20 Sep 2016, In : Nanoscale Research Letters. 11, 11 p., 413.

Research output: Contribution to journalArticleScientificpeer-review

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Enhancement of Bioavailability and Pharmacodynamic Effects of Thymoquinone Via Nanostructured Lipid Carrier (NLC) Formulation

Elmowafy, M., Samy, A., Raslan, M. A., Salama, A., Said, R. A., Abdelaziz, A. E., El-Eraky, W., El Awdan, S. & Viitala, T., Jun 2016, In : AAPS PharmSciTech. 17, 3, p. 663-672 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Estradiol-tethered micropatterned surfaces for the study of estrogenic non-genomic pathways

Qi, B., Shimizu, Y., Nakanishi, J. & Winnik, F. M., 2016, In : Chemical Communications. 52, 65, p. 10056-10059 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Etnofarmakologia voi auttaa löytämään uusia lääkeaineita luonnosta

Fyhrqvist, P. J., 2016, In : Sic! Lääketietoa Fimeasta. 6, 3, p. 21-23 3 p.

Research output: Contribution to journalArticleProfessional

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Evaluation of crumb rubber as aggregate for automated manufacturing of rubberized long hollow blocks and bricks

Sodupe-Ortega, E., Fraile-Garcia, E., Ferreiro-Cabello, J. & Sanz-Garcia, A., 1 Mar 2016, In : Construction and Building Materials. 106, p. 305-316 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

Fais, S., O'Driscoll, L., Borras, F. E., Buzas, E., Camussi, G., Cappello, F., Carvalho, J., da Silva, A. C., Del Portillo, H., El Andaloussi, S., Trcek, T. F., Furlan, R., Hendrix, A., Gursel, I., Kralj-Iglic, V., Kaeffer, B., Kosanovic, M., Lekka, M. E., Lipps, G., Logozzi, M. & 17 othersMarcilla, A., Sammar, M., Llorente, A., Nazarenko, I., Oliveira, C., Pocsfalvi, G., Rajendran, L., Raposo, G., Rohde, E., Siljander, P., van Niel, G., Vasconcelos, M. H., Yanez-Mo, M., Yliperttula, M. L., Zarovni, N., Zavec, A. B. & Giebel, B., Apr 2016, In : ACS Nano. 10, 4, p. 3886-3899 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Exploration of Microbial Communities Using the Thermo Scientific Varioskan LUX Multimode Reader and the Invitrogen EVOS FL Cell Imaging System

Hiltunen, A., Skogman, M., Vuorela, P. M. & Fallarero, A., Oct 2016, In : BioTechniques. 61, 4, p. 214-215 2 p.

Research output: Contribution to journalArticleScientific

Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity

Hirvinen, M., Capasso, C., Guse, K., Garofalo, M., Vitale, A., Ahonen, M., Kuryk, L., Vähä-Koskela, M., Hemminki, A., Fortino, V., Greco, D. & Cerullo, V., 23 Mar 2016, In : Molecular Therapy - Oncolytics. 3, 9 p., 16002.

Research output: Contribution to journalArticleScientificpeer-review

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Factorial design formulation optimization and in vitro characterization of curcumin-loaded PLGA nanoparticles for colon delivery

Akl, M. A., Kartal-Hodzic, A., Oksanen, T., Ismael, H. R., Afouna, M. M., Yliperttula, M., Samy, A. M. & Viitala, T., Apr 2016, In : Journal of Drug Delivery Science and Technology. 32, part A, p. 10-20 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Farmasian opetus uudistuu - näkyykö ympäristönäkökulma?

Salminen, O. S., 1 Jun 2016, In : Suomen apteekkarilehti. Blogivieras 26.5.2016, 1 p.

Research output: Contribution to journalArticleProfessional

Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

Baghirov, H., Karaman, D., Viitala, T., Duchanoy, A., Lou, Y-R., Mamaeva, V., Pryazhnikov, E., Khiroug, L., Davies, C. D. L., Sahlgren, C. & Rosenholm, J. M., 22 Aug 2016, In : PLoS One. 11, 8, 22 p., 0160705.

Research output: Contribution to journalArticleScientificpeer-review

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First In Vivo Detection and Characterization of Hyaluronan-Coated Extracellular Vesicles in Human Synovial Fluid

Mustonen, A-M., Nieminen, P., Joukainen, A., Jaroma, A., Kääriäinen, T., Kröger, H., Lazaro-Ibanez, E., Siljander, P. R-M., Kärjä, V., Härkönen, K., Koistinen, A. & Rilla, K., Nov 2016, In : Journal of Orthopaedic Research. 34, 11, p. 1960-1968 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Flavones as Quorum Sensing Inhibitors Identified by a Newly Optimized Screening Platform Using Chromobacterium violaceum as Reporter Bacteria

Skogman, M. E., Kanerva, S., Manner, S., Vuorela, P. M. & Fallarero, A., Sep 2016, In : Molecules. 21, 9, 11 p., 1211.

Research output: Contribution to journalArticleScientificpeer-review

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Fluorescence-suppressed time-resolved Raman spectroscopy of pharmaceuticals using complementary metal-oxide semiconductor (CMOS) single-photon avalanche diode (SPAD) detector

Rojalin, T., Kurki, L., Laaksonen, T., Viitala, T., Kostamovaara, J., Gordon, K. C., Galvis, L., Wachsmann-Hogiu, S., Strachan, C. J. & Yliperttula, M., 2016, In : Analytical and Bioanalytical Chemistry. 408, 3, p. 761-774 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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Functional double-shelled silicon nanocrystals for two-photon fluorescence cell imaging: spectral evolution and tuning

Chandra, S., Ghosh, B., Beaune, G., Nagarajan, U., Yasui, T., Nakamura, J., Tsuruoka, T., Baba, Y., Shirahata, N. & Winnik, F. M., 2016, In : Nanoscale. 8, 16, p. 9009-9019 11 p.

Research output: Contribution to journalArticleScientificpeer-review

General Pharmacokinetic Model for Topically Administered Ocular Drug Dosage Forms

Deng, F., Ranta, V-P., Kidron, H. & Urtti, A., Nov 2016, In : Pharmaceutical Research. 33, 11, p. 2680-2690 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Generation of membrane-bound catechol-O-methyl transferase deficient mice with disctinct sex dependent behavioral phenotype.

Tammimäki, A. E., Aonurm-Helm, A., Zhang, F-P., Poutanen, M., Duran Torres, G., Garcia Horsman, J. A. & Männistö, P. T., 31 Dec 2016, In : Journal of Physiology and Pharmacology. 67, 6, p. 827-842 15 p.

Research output: Contribution to journalArticleScientificpeer-review

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Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease

Hyötyläinen, T., Jerby, L., Petäjä, E. M., Mattila, I., Jäntti, S., Auvinen, P., Gastaldelli, A., Yki-Järvinen, H., Ruppin, E. & Oresic, M., Feb 2016, In : Nature Communications. 7, 9 p., 8994.

Research output: Contribution to journalArticleScientificpeer-review

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Gold Nanorods, DNA Origami, and Porous Silicon Nanoparticle-functionalized Biocompatible Double Emulsion for Versatile Targeted Therapeutics and Antibody Combination Therapy

Kong, F., Zhang, H., Qu, X., Zhang, X., Chen, D., Ding, R., Mäkilä, E., Salonen, J., Santos, H. A. & Hai, M., 14 Dec 2016, In : Advanced Materials. 28, 46, p. 10195-10203 9 p.

Research output: Contribution to journalArticleScientificpeer-review

HDAC inhibition in the cpfl1 mouse protects degenerating cone photoreceptors in vivo

Trifunovic, D., Arango-Gonzalez, B., Comitato, A., Barth, M., del Amo, E. M., Kulkarni, M., Sahaboglu, A., Hauck, S. M., Urtti, A., Arsenijevic, Y., Ueffing, M., Marigo, V. & Paquet-Durand, F., 15 Oct 2016, In : Human Molecular Genetics. 25, 20, p. 4462-4472 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Hepatic differentiation of human pluripotent stem cells on human liver progenitor HepaRG-derived acellular matrix

Kanninen, L. K., Porola, P., Niklander, J., Malinen, M. M., Corlu, A., Guguen-Guillouzo, C., Urtti, A., Yliperttula, M. L. & Lou, Y-R., 15 Feb 2016, In : Experimental Cell Research. 341, 2, p. 207-217 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Histamine H3 receptor antagonist decreases cue-induced alcohol reinstatement in mice

Nuutinen, S., Mäki, T., Rozov, S., Bäckström, P., Hyytiä, P., Piepponen, P. & Panula, P., Jul 2016, In : Neuropharmacology. 106, p. 156-163 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Histamine H3 Receptor Regulates Sensorimotor Gating and Dopaminergic Signaling in the Striatum

Kononoff-Vanhanen, J., Nuutinen, S. K., Tuominen, M. & Panula, P., 2016, In : Journal of Pharmacology and Experimental Therapeutics. 357, 2, p. 264-272 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Hospital and Community Pharmacists’ Perceptions of Which Competences Are Important for Their Practice

Atkinson, J., Sánchez Pozo, A., Rekkas, D., Volmer, D., Hirvonen, J., Bozic, B., Skowron, A., Mircioiu, C., Sandulovici, R., Marcincal, A., Koster, A., Wilson, K. A., van Schravendijk, C., Frontini, R., Price, R., Bates, I. & De Paepe, K., 2016, In : Pharmacy. 4, 2, 21.

Research output: Contribution to journalArticleScientificpeer-review

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Hotel Reservation Forecasting Using Flexible Soft Computing Techniques: A Case of Study in a Spanish Hotel

Martinez-De-Pison, E., Fernandez-Ceniceros, J., Pernia-Espinoza, A. V., Martinez-De-Pison, F. J. & Sanz-Garcia, A., Sep 2016, In : International Journal of Information Technology and Decision Making. 15, 5, p. 1211-1234 24 p.

Research output: Contribution to journalArticleScientificpeer-review

How Do European Pharmacy Students Rank Competences for Practice?

Atkinson, J., De Paepe, K., Sánchez Pozo, A., Rekkas, D., Volmer, D., Hirvonen, J., Bozic, B., Skowron, A., Mircioiu, C., Marcincal, A., Koster, A., Wilson, K., van Schravendijk, C. & Hočevar, S., 2016, In : Pharmacy. 4, 1

Research output: Contribution to journalArticleScientificpeer-review

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Human gut microbes impact host serum metabolome and insulin sensitivity

Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyötyläinen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., Le Chatelier, E., Levenez, F., Dore, J., Mattila, I., Plichta, D. R., Pöhö, P., Hellgren, L. I., Arumugam, M., Sunagawa, S., Vieira-Silva, S. & 14 othersJorgensen, T., Holm, J. B., Trost, K., Kristiansen, K., Brix, S., Raes, J., Wang, J., Hansen, T., Bork, P., Brunak, S., Oresic, M., Ehrlich, S. D., Pedersen, O. & MetaHIT Consortium, 21 Jul 2016, In : Nature. 535, 7612, p. 376-381 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Human stem cell decorated nanocellulose threads for biomedical applications

Mertaniemi, H., Escobedo-Lucea, C., Sanz-Garcia, A., Gandía, C., Mäkitie, A., Partanen, J., Ikkala, O. & Yliperttula, M., Mar 2016, In : Biomaterials. 82, p. 208-220 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Hyttyset levittävät viruksia Suomessakin, ja asiantuntijan mukaan uusien virusten leviämistä on syytä seurata

Hanski, L. L., 10 Sep 2016, In : Helsingin Sanomat. 2016, 10.9.2016, 1 p.

Research output: Contribution to journalArticleGeneral public

Open Access

Iäkkään lääkehoidon riskien arviointimittari kotihoidon lähi- ja perushoitajille

Dimitrow, M., Leikola, S., Puustinen, J., Airaksinen, M. & Kivelä, S-L., 2016, In : Yleislääkäri. 31, 6, p. 23-29 7 p.

Research output: Contribution to journalArticleProfessional

Iäkkään lääkehoidon riskien arvioitimittari kotihoidon lähi- ja perushoitajille

Dimitrow, M., Leikola, S., Puustinen, J., Airaksinen, M. & Kivelä, S-L., 19 Oct 2016, In : Yleislääkäri. 31, 6, p. 23-29 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

IDAAPM: integrated database of ADMET and adverse effects of predictive modeling based on FDA approved drug data

Legehar, A., Xhaard, H. & Ghemtio, L., 14 Jun 2016, In : Journal of Cheminformatics. 8, 11 p., 33.

Research output: Contribution to journalArticleScientificpeer-review

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Imbalance of plasma amino acids, metabolites and lipids in patients with lysinuric protein intolerance (LPI)

Kurko, J., Tringham, M., Tanner, L., Nanto-Salonen, K., Vähä-Mäkilä, M., Nygren, H., Pöhö, P., Lietzen, N., Mattila, I., Olkku, A., Hyötyläinen, T., Oresic, M., Simell, O., Niinikoski, H. & Mykkänen, J., Sep 2016, In : Metabolism, clinical and experimental. 65, 9, p. 1361-1375 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes

Galli, E., Harkonen, T., Sainio, M., Ustav, M., Toots, U., Urtti, A., Yliperttula, M., Lindahl, M., Knip, M., Saarma, M. & Lindholm, P., 30 Jun 2016, In : Scientific Reports. 6, 11 p., 29058.

Research output: Contribution to journalArticleScientificpeer-review

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