Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications 1983 2019

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2019

Tissue-specific study across the stem reveals the chemistry and transcriptome dynamics of birch bark.

Alonso Serra, J. A., Safronov, O., Lim, K-J., Fraser-Miller, S., Blokhina, O. B., Campilho, A., Chong, S-L., Fagerstedt, K. V., Haavikko, R. H., Helariutta, Y., Immanen, J. J. M., Kangasjärvi, J. S., Kauppila, T. J., Lehtonen, M., Ragni, L., Rajaraman, S., Räsänen, R-M., Safdari, P., Tenkanen, T. M., Yli-Kauhaluoma, J. T. & 4 othersTeeri, T. H., Strachan, C. J., Nieminen, K. & Salojärvi, J. T., Jun 2019, In : New Phytologist. 222, 4, p. 1816-1831 16 p.

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Use of telephone and web interfaces of interactive response technology at clinical investigator sites in clinical trials

Saarela, A-L., Walzer, A. & Juppo, A. M., Jun 2019, In : Clinical trials : journal of the Society for Clinical Trials. 16, 3, p. 297-305 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Using microfluidic platforms to develop CNS-targeted polymeric nanoparticles for HIV therapy

Martins, C., Araújo, F., Gomes, M. J., Fernandes, C., Nunes, R., Li, W., Santos, H. A., Borges, F. & Sarmento, B., May 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 138, p. 111-124 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Withdrawal from long-term use of zopiclone, zolpidem and temazepam may improve perceived sleep and quality of life in older adults with primary insomnia

Lähteenmäki, R., Neuvonen, P. J., Puustinen, J., Vahlberg, T., Partinen, M., Räihä, I. & Kivelä, S-L., Mar 2019, In : Basic & Clinical Pharmacology & Toxicology. 124, 3, p. 330-340 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Yliopistouralla etenemisen sietämätön vaikeus: Raportti uramallikyselyn tuloksista

Toikkanen, J., Holm, Y. & Giesecke, S., 29 Apr 2019, In : Acatiimi : Professoriliiton, Tieteentekijöiden liiton ja Yliopistonlehtorien liiton lehti. 22, 3, p. 36-39 4 p.

Research output: Contribution to journalArticleProfessional

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α-Amino diphenyl phosphonates as novel inhibitors of Escherichia coli ClpP protease

Moreno-Cinos, C., Sassetti, E., Salado, I. G., Witt, G., Benramdane, S., Reinhardt, L., Cruz, C. D., Joossens, J., Van der Veken, P., Brötz-Oesterhelt, H., Tammela, P. S. M., Winterhalter, M., Gribbon, P., Windshügel, B. & Augustyns, K., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 774-797 24 p.

Research output: Contribution to journalArticleScientificpeer-review

2018

3D printed UV light cured polydimethylsiloxane devices for drug delivery

Hollander, J., Hakala, R., Suominen, J., Moritz, N., Yliruusi, J. & Sandler, N., 15 Jun 2018, In : International Journal of Pharmaceutics. 544, 2, p. 433-442 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation

Richardson, D., Itkonen, J., Nievas, J., Urtti, A. & Casteleijn, M. G., 10 Aug 2018, In : Scientific Reports. 8, 1, 11 p., 11967 .

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Accurate Calibration in Multi-Material 3D Bioprinting for Tissue Engineering

Sodupe-Ortega, E., Sanz-Garcia, A., Pernia-Espinoza, A. & Escobedo-Lucea, C., 10 Aug 2018, In : Materials. 11, 8, 19 p., 1402.

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Adenosine analogs bearing phosphate isosteres as human MDO1 ligands

Zhang, Y., Jumppanen, A. M., Maksimainen, M. M., Auno, A. S., Awol, Z., Ghemtio, L., Venkannagari, H., Lehtiö, L., Yli-Kauhaluoma, J., Xhaard, H. & Boije af Gennäs, G., 1 May 2018, In : Bioorganic & Medicinal Chemistry. 26, 8, p. 1588-1597 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Adjustable hardness of hydrogel for promoting vascularization and maintaining stemness of stem cells in skin flap regeneration

Sun, X., Zhang, H., He, J., Cheng, R., Cao, Y., Che, K., Cheng, L., Zhang, L., Pan, G., Ni, P., Deng, L., Zhang, Y., Almeida Santos, H. & Cui, W., Dec 2018, In : Applied materials today. 13, p. 54-63 10 p.

Research output: Contribution to journalArticleScientificpeer-review

A feasibility study of the toxic responses of human induced pluripotent stem cell-derived hepatocytes to phytochemicals

Smutný, T., Harjumäki, R., Kanninen, L., Yliperttula, M. L., Pávek, P. & Lou, Y-R., Oct 2018, In : Toxicology in Vitro. 52, p. 94-105 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Alkaloid-Rich Crude Extracts, Fractions and Piperamide Alkaloids of Piper guineense Possess Promising Antibacterial Effects

Mgbeahuruike, E. E., Fyhrquist, P., Vuorela, H., Julkunen-Tiitto, R. & Holm, Y., Dec 2018, In : Antibiotics. 7, 4, 18 p., 98.

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Amphetamine primes enhanced motivation toward uncertain choices in rats with genetic alcohol preference

Oinio, V., Sundström, M., Bäckström, P., Uhari-Väänänen, J., Kiianmaa, K., Raasmaja, A. & Piepponen, P., May 2018, In : Psychopharmacology. 235, 5, p. 1361-1370 10 p.

Research output: Contribution to journalArticleScientificpeer-review

A national approach to medicines information research: a systematic review

Mononen, N. M., Järvinen, R., Hämeen-Anttila, K., Airaksinen, M. S. A., Bonhomme, C., Kleme, J. & Pohjanoksa-Mäntylä, M., Dec 2018, In : Research in Social and Administrative Pharmacy. 14, 12, p. 1106-1124 19 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

An immunological electrospun scaffold for tumor cell killing and healthy tissue regeneration

Liu, X., Zhang, H., Cheng, R., Gu, Y., Yin, Y., Sun, Z., Pan, G., Deng, Z., Yang, H., Deng, L., Cui, W., Almeida Santos, H. & Shi, Q., 1 Nov 2018, In : Materials Horizons. 5, 6, p. 1082-1091 10 p.

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Antibioottiresistenssi - jätevedessä sen alku ja loppu

Elsilä, L., Feb 2018, In : Proviisorilehti. 1, p. 22-23 2 p.

Research output: Contribution to journalArticleProfessional

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Antitumor effect of oncolytic virus and paclitaxel encapsulated in extracellular vesicles for lung cancer treatment

Garofalo, M., Saari, H., Somersalo, P., Crescenti, D., Kuryk, L., Aksela, L., Capasso, C., Madetoja, M., Koskinen, K., Oksanen, T., Mäkitie, A., Jalasvuori, M., Cerullo, V., Ciana, P. & Yliperttula, M., 1 Jun 2018, In : Journal of Controlled Release. 283, p. 223-234 12 p.

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Antitumor-specific T-cell responses induced by oncolytic adenovirus ONCOS-102 (AdV5/3-D24-GM-CSF) in peritoneal mesothelioma mouse model

Kuryk, L., Moller, A-S. W., Garofalo, M., Cerullo, V., Pesonen, S., Alemany, R. & Jaderberg, M., Oct 2018, In : Journal of Medical Virology. 90, 10, p. 1669-1673 5 p.

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Arginine-rich cell-penetrating peptides induce membrane multilamellarity and subsequently enter via formation of a fusion pore

Allolio, C., Magarkar, A., Jurkiewicz, P., Baxova, K., Javanainen, M., Mason, P. E., Sachl, R., Cebecauer, M., Hof, M., Horinek, D., Heinz, V., Rachel, R., Ziegler, C. M., Schröfel, A. & Jungwirth, P., 20 Nov 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 47, p. 11923-11928 6 p.

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Attenuated dopaminergic neurodegeneration and motor dysfunction in hemiparkinsonian mice lacking the α5 nicotinic acetylcholine receptor subunit

Leino, S., Koski, S. K., Hänninen, R., Tapanainen, T., Rannanpää, S. & Salminen, O., 28 Jun 2018, In : Neuropharmacology. 138, p. 371-380 9 p.

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A versatile strategy for the synthesis of 4,5-dihydroxy-2,3-pentadione (DPD) and related compounds as potential modulators of bacterial quorum sensing

Stotani, S., Gatta, V., Medda, F., Padmanaban, M., Karawajzyk, A., Tammela, P. S. M., Giordanetto, F., Tzalis, D. & Collina, S., 6 Oct 2018, In : Molecules. 23, 10, 22 p., 2545.

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Azulene-based compounds for targeting orexin receptors

Leino, T. O., Turku, A., Yli-Kauhaluoma, J. T., Kukkonen, J. P., Xhaard, H. & Wallén, E. A. A., 5 Sep 2018, In : European Journal of Medicinal Chemistry. 157, p. 88-100 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Bare laser-synthesized Au-based nanoparticles as nondisturbing surface-enhanced Raman scattering probes for bacteria identification

Kögler, M., Ryabchikov, Y. V., Uusitalo, S., Popov, A., Popov, A., Tselikov, G., Välimaa, A-L., Al-Kattan, A., Hiltunen, J., Laitinen, R., Neubauer, P., Meglinski, I. & Kabashin, A. V., Jul 2018, In : Journal of Biophotonics. 11, 7, 10 p., 201700225.

Research output: Contribution to journalArticleScientificpeer-review

Barriers and facilitators to medication adherence: a qualitative study with general practitioners

Kvarnström, K., Airaksinen, M. & Liira, H., Jan 2018, In : BMJ Open. 8, 1, 8 p., 015332.

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Bentsodiatsepiinien pitkäaikaiskäyttö on vähentynyt

Kurko, T., Saastamoinen, L., Tuulio-Henriksson, A., Taiminen, T., Tiihonen, J., Airaksinen, M. & Hietala, J., 2018, In : Suomen lääkärilehti. 73, 20, p. 1292-1297 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Binding of Small Molecule Drugs to Porcine Vitreous Humor

Rimpelä, A-K., Reunanen, S., Hagström, M., Kidron, H. & Urtti, A., Jun 2018, In : Molecular Pharmaceutics. 15, 6, p. 2174-2179 6 p.

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Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate-Induced Excitotoxicity

Liu, D., Chen, J., Jiang, T., Li, W., Huang, Y., Lu, X., Liu, Z., Zhang, W., Zhou, Z., Ding, Q., Almeida Santos, H., Yin, G. & Fan, J., 14 Feb 2018, In : Advanced Materials. 30, 14, 11 p., 1706032.

Research output: Contribution to journalArticleScientificpeer-review

Bioengineered Porous Silicon Nanoparticles@Macrophages Cell Membrane as Composite Platforms for Rheumatoid Arthritis

Fontana, F., Albertini, S., Correia, A., Kemell, M. L., Lindgren, R., Mäkilä, E., Salonen, J., Hirvonen, J. T., Ferrari, F. & Almeida Santos, H., 30 May 2018, In : Advanced Functional Materials. 28, 22, 10 p., 1801355.

Research output: Contribution to journalArticleScientificpeer-review

Biological treatment in ankylosing spondylitis in the Nordic countries during 2010-2016: a collaboration between five biological registries

DANBIO Registry, SRQ ARTIS Registry, ROB-FIN Registry, NOR-DMARD Registry & ICEBIO Registry, 2 Nov 2018, In : Scandinavian Journal of Rheumatology. 47, 6, p. 465-474 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements

Parkkila, P., Elderdfi, M., Bunker, A. & Viitala, T., 10 Jul 2018, In : Langmuir. 34, 27, p. 8081-8091 11 p.

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Biotransformation of Cyclodextrine-Complexed Semisynthetic Betulin Derivatives by Plant Cells

Häkkinen, S. T., Nygren, H., Maiorova, N., Haavikko, R., Alakurtti, S., Yli-Kauhaluoma, J., Rischer, H. & Oksman-Caldentey, K-M., 1 Jul 2018, In : Planta Medica. 84, 9/10, p. 743-748 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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Can Practical Nurses Identify Older Home Care Clients at Risk of Drug-Related Problems-Geriatricians' Appraisal of Their Risk Screenings: A Pilot Study

Dimitrow, M., Puustinen, J., Viikari, P., Puumalainen, E., Vahlberg, T., Airaksinen, M. S. A. & Kivelä, S-L., Jun 2018, In : Journal of Pharmacy Technology. 34, 3, p. 99-108 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4–NKX2-5 Interaction

Kinnunen, S. M., Tölli, M. A., Välimäki, M. J., Gao, E., Szabo, Z., Rysä, J., Almeida Ferreira, M. P., J. Ohukainen, P., Serpi, R., Correia, A., Makila, E., Salonen, J., Hirvonen, J. T., Almeida Santos, H. & Ruskoaho, H. J., 15 Mar 2018, In : Scientific Reports. 8, 14 p., 4611 .

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Catalytic, Tunable, One-Step Bismuth(III) Triflate Reaction with Alcohols: Dehydration Versus Dimerization

Kolsi, L. E., Yli-Kauhaluoma, J. & Moreira, V. M., 9 Aug 2018, In : ACS Omega. 3, 8, p. 8836–8842 7 p.

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Cell Membrane-Based Nanoreactor To Mimic the Bio-Compartmentalization Strategy of a Cell

Balasubramanian, V., Poillucci, A., Correia, A., Zhang, H., Celia, C. & Santos, H. A., Apr 2018, In : Acs Biomaterials Science & Engineering. 4, 4, p. 1471-1478 8 p.

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Characteristics of Hot Water Extracts from the Bark of Cultivated Willow (Salix sp.)

Dou, J., Xu, W., Koivisto, J. J., Mobley, J. K., Padmakshan, D., Koegler, M., Xu, C., Willfor, S., Ralph, J. & Vuorinen, T., Apr 2018, In : ACS Sustainable Chemistry & Engineering. 6, 4, p. 5566-5573 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of membrane–foulant interactions with novel combination of Raman spectroscopy, surface plasmon resonance and molecular dynamics simulation

Virtanen, T., Parkkila, P., Koivuniemi, A., Lahti, J., Viitala, T., Kallioinen, M., Mänttäri, M. & Bunker, A., 23 May 2018, In : Separation and Purification Technology. 205, p. 263-272 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Cisplatin Encapsulation Generates Morphologically Different Multicompartments in the Internal Nanostructures of Nonlamellar Liquid-Crystalline Self-Assemblies

Azmi, I. D. M., Ostergaard, J., Sturup, S., Gammelgaard, B., Urtti, A., Moghimi, S. M. & Yaghmur, A., 5 Jun 2018, In : Langmuir. 34, 22, p. 6570-6581 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions

Kahma, H., Filppula, A. M., Neuvonen, M., Tarkiainen, E. K., Tornio, A., Holmberg, M. T., Itkonen, M. K., Finel, M., Neuvonen, P. J., Niemi, M. & Backman, J. T., 1 Feb 2018, In : Drug Metabolism and Disposition. 46, 2, p. 141-150 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease

Huotarinen, A., Penttinen, A-M., Bäck, S., Voutilainen, M. H., Julku, U., Piepponen, T. P., Männistö, P. T., Saarma, M., Tuominen, R., Laakso, A. & Airavaara, M., 15 Mar 2018, In : Neuroscience. 374, p. 250-263 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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Community pharmacists' knowledge of COPD, and practices and perceptions of medication counseling of COPD patients

Heikkilä, J. M., Parkkamäki, S., Salimäki, J., Westermarck, S. & Pohjanoksa-Mantyla, M., 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 2065-2074 10 p.

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Comparative Proteomic Analysis of Hymenolepis diminuta Cysticercoid and Adult Stages

Sulima, A., Savijoki, K., Bien, J., Nareaho, A., Salamatin, R., Conn, D. B. & Mlocicki, D., 15 Jan 2018, In : Frontiers in Microbiology. 8, 14 p., 2672.

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Comparison of melibiose and trehalose as stabilising excipients for spray-dried β-galactosidase formulations

Lipiäinen, T., Räikkönen, H., Kolu, A-M., Peltoniemi, M. & Juppo, A., 2018, In : International Journal of Pharmaceutics. 543, 1-2, p. 21-28 8 p.

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Comparison of time-gated surface-enhanced raman spectroscopy (TG-SERS) and classical SERS based monitoring of Escherichia coli cultivation samples

Kögler, M., Paul, A., Anane, E., Birkholz, M., Bunker, A., Viitala, T., Maiwald, M., Junne, S. & Neubauer, P., 2018, In : Biotechnology Progress. 34, 6, p. 1533-1542 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Conditioned Reward of Opioids, but not Psychostimulants, is Impaired in GABA-A Receptor δ Subunit Knockout Mice

Siivonen, M. S., de Miguel, E., Aaltio, J., Manner, A. K., Vahermo, M., Yli-Kauhaluoma, J., Linden, A-M., Aitta-aho, T. & Korpi, E. R., 9 Oct 2018, In : Basic & Clinical Pharmacology & Toxicology. 123, 5, p. 558-566 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Conductive vancomycin-loaded mesoporous silica polypyrrole-based scaffolds for bone regeneration

Ezazi, N. Z., Shahbazi, M-A., Shatalin, Y. V., Nadal, E., Mäkilä, E., Salonen, J., Kemell, M., Correia, A., Hirvonen, J. & Santos, H. A., 30 Jan 2018, In : International Journal of Pharmaceutics. 536, 1, p. 241-250 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine

Kopra, J., Villarta-Aguilera, M., Savolainen, M., Weingerl, S., Myohänen, T. T., Rannanpää, S., Salvatore, M. E., Andressoo, J-O. & Piepponen, T. P., Jan 2018, In : Neuropharmacology. 128, p. 221-230 10 p.

Research output: Contribution to journalArticleScientificpeer-review