Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications

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2019

Chemical analysis using 3D printed glass microfluidics

Gal-Or, E., Gershoni, Y., Scotti, G., Nilsson, S. M. E., Saarinen, J. K. S., Jokinen, V. P., Strachan, C. J., Boije af Gennäs, P. G., Yli-Kauhaluoma, J. T. & Kotiaho, A. A. T., 7 Apr 2019, In : Analytical Methods. 11, 13, p. 1802-1810 9 p.

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Chemical characteristics and stability of eucalyptus kraft pulps bleached with tertiary amine catalyzed hypochlorous acid

Afsahi, G., Rojalin, T. & Vuorinen, T., Feb 2019, In : Cellulose. 26, 3, p. 2047-2054 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Chemical profiles of birch and alder bark by ambient mass spectrometry

Räsänen, R-M., Hieta, J-P., Immanen, J., Nieminen, K., Haavikko, R., Yli-Kauhaluoma, J. & Kauppila, T. J., Nov 2019, In : Analytical and Bioanalytical Chemistry. 411, 28, p. 7573-7583 11 p.

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Close-loop dynamic nanohybrids on collagen-ark with in situ gelling transformation capability for biomimetic stage-specific diabetic wound healing

Liu, Z., Li, Y., Li, W., Lian, W., Kemell, M., Hietala, S., Figueiredo, P., Li, L., Mäkilä, E., Ma, M., Salonen, J., Hirvonen, J. T., Liu, D., Zhang, H., Deng, X. & Santos, H. A., 1 Feb 2019, In : Materials Horizons. 6, 2, p. 385-393 9 p.

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Connective Tissue Growth Factor Inhibition Enhances Cardiac Repair and Limits Fibrosis After Myocardial Infarction

Vainio, L., Szabo, Z., Lin, R., Ulvila, J., Yrjölä, R., Alakoski, T., Piuhola, J., Koch, W. J., Ruskoaho, H., Fouse, SD., Seeley, TW., Gao, E., Signore, P., Lipson, K. E., Magga, J. & Kerkelä, R., 25 Feb 2019, In : JACC : Basic to Translational Science. 4, 1, p. 83-94 12 p.

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Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles

Clayton, A., Boilard, E., Buzas, E. I., Cheng, L., Falcón-Perez, J. M., Gardiner, C., Gustafson, D., Gualerzi, A., Hendrix, A., Hoffman, A., Jones, J., Lässer, C., Lawson, C., Lenassi, M., Nazarenko, I., O’Driscoll, L., Pink, R., Siljander, P. R-M., Soekmadji, C., Wauben, M. & 4 others, Welsh, J. A., Witwer, K., Zheng, L. & Nieuwland, R., 1 Dec 2019, In : Journal of Extracellular Vesicles. 8, 1, 5 p., 1647027.

Research output: Contribution to journalArticleScientific

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Correction Self-Healing and Injectable Hydrogel for Matching Skin Flap Regeneration

Mao, X., Cheng, R., Zhang, H., Bae, J., Cheng, L., Zhang, L., Deng, L., Cui, W., Zhang, Y., Almeida Santos, H. & Sun, X., 3 Jul 2019, In : Advanced Science. 6, 13, 2 p., 1901124.

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Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses

Kohtala, H. S., Theilmann, W., Rosenholm, M., Penna, L., Karabulut, G., Uusitalo, S., Järventausta, K., Yli-Hankala, A., Yalcin, I., Matsui, N., Wigren, H-K. & Rantamäki, T., Jun 2019, In : Molecular Neurobiology. 56, 6, p. 4163-4174 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Cost-effectiveness of abatacept, tocilizumab and TNF-inhibitors compared with rituximab as second-line biologic drug in rheumatoid arthritis

Huoponen, S., Aaltonen, K. J., Viikinkoski, J., Rutanen, J., Relas, H., Taimen, K., Puolakka, K., Nordström, D. & Blom, M., 24 Jul 2019, In : PLoS One. 14, 7, 14 p., 0220142.

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Data on biosynthesis of BPAF glucuronide, enzyme kinetics of BPAF glucuronidation, and molecular modeling

Skledar, D. G., Trontelj, J., Troberg, J., Tomašič, T., Zega, A., Finel, M. & Mašič, L. P., Feb 2019, In : Data in Brief. 22, p. 977-986 10 p.

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Dehydroabietylamine-Based Cellulose Nanofibril Films: A New Class of Sustainable Biomaterials for Highly Efficient, Broad-Spectrum Antimicrobial Effects

Hassan, G. A. M. S., Forsman, N., Wan, X., Keurulainen, L., Bimbo, L. M., Johansson, L-S., Sipari, N., Yli-Kauhaluoma, J. T., Zimmermann, R., Stehl, S., Werner, C., Saris, P. E. J., Österberg, M. & Moreira, V. M., 4 Mar 2019, In : ACS Sustainable Chemistry & Engineering. 7, 5, p. 5002-5009 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Design and evaluation of a multiplexed angular-scanning surface plasmon resonance system employing line-laser optics and CCD detection in combination with multi-ligand sensor chips

Lakayan, D., Tuppurainen, J., Suutari, T. E., van Iperen, D. J., Somsen, G. W. & Kool, J., 1 Mar 2019, In : Sensors and Actuators B: Chemical. 282, p. 243-250 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Determinants of Orexin Receptor Binding and Activation—A Molecular Dynamics Study

Karhu, L., Magarkar, A., Bunker, A. & Xhaard, H., 28 Mar 2019, In : Journal of Physical Chemistry B. 123, 12, p. 2609-2622 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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Developing a procedure for medication reconciliation and review on admission to geriatric wards

Riukka, L. H., Niskanen, A. E., Holmström, A-R., Hakoinen, S., Lavonius, S., Airaksinen, M. & Laaksonen, R., 2019, In : Dosis : farmaseuttinen aikakauskirja. 35, 1, p. 20-41 22 p.

Research output: Contribution to journalArticleScientificpeer-review

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Direct Measurement of Amorphous Solubility

Stukelj, J., Svanback, S., Agopov, M., Lobmann, K., Strachan, C. J., Rades, T. & Yliruusi, J., 4 Jun 2019, In : Analytical Chemistry. 91, 11, p. 7411-7417 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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Distribution of Small Molecular Weight Drugs into the Porcine Lens: Studies on Imaging Mass Spectrometry, Partition Coefficients, and Implications in Ocular Pharmacokinetics

Heilkkinen, E. M., Auriola, S., Ranta, V-P., Demarais, N. J., Grey, A. C., del Amo, E. M., Toropainen, E., Vellonen, K-S., Urtti, A. & Ruponen, M., Sep 2019, In : Molecular Pharmaceutics. 16, 9, p. 3968-3976 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Dose-dependent effects of isoflurane on TrkB and GSK3β signaling: Importance of burst suppression pattern

Theilmann, W., Alitalo, O. A., Yorke, I. & Rantamäki, T. P. J., 16 Feb 2019, In : Neuroscience Letters. 694, p. 29-33 5 p.

Research output: Contribution to journalArticleScientificpeer-review

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DPD-inspired discovery of novel LsrK kinase inhibitors: an opportunity to fight antimicrobial resistance

Stotani, S., Gatta, V., Medarametla, P., Padmanaban, M., Karawajzyk, A., Giordanetto, F., Tammela, P., Laitinen, T., Poso, A., Tzalis, D. & Collina, S., 14 Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2720-2737 18 p.

Research output: Contribution to journalArticleScientificpeer-review

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Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors

Diniz, C. R. A. F., Biojone, C., Joca, S. R. L., Rantamäki, T., Castren, E., Guimaraes, F. S. & Casarotto, P. C., 21 Feb 2019, In : PeerJ. 7, 21 p., 6493.

Research output: Contribution to journalArticleScientificpeer-review

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Effect of headspace gas on nucleation of amorphous paracetamol

Palomäki, E. A. K., Yliruusi, J. K. & Ehlers, H., Jun 2019, In : Journal of Drug Delivery Science and Technology. 51, p. 127-138 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Effects of nanofibrillated cellulose hydrogels on adipose tissue extract and hepatocellular carcinoma cell spheroids in freeze-drying

Auvinen, V-V., Merivaara, A., Kiiskinen, J., Paukkonen, H., Laurén, P., Hakkarainen, T., Koivuniemi, R., Sarkanen, R., Ylikomi, T., Laaksonen, T. & Yliperttula, M., 15 Sep 2019, In : Cryobiology. 91, p. 137-145 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Efficient Fabrication of Polycaprolactone Scaffolds for Printing Hybrid Tissue-Engineered Constructs

Sodupe Ortega, E., Sanz-Garcia, A., Pernia-Espinoza, A. & Escobedo-Lucea, C., 2 Feb 2019, In : Materials. 12, 4, 18 p., 613.

Research output: Contribution to journalArticleScientificpeer-review

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Efflux transport of nicotine, cotinine and trans-3 '-hydroxycotinine glucuronides by human hepatic transporters

Jarvinen, E., Sjöstedt, N., Koenderink, J. B., Kidron, H. & Finel, M., Dec 2019, In : Basic & Clinical Pharmacology & Toxicology. 125, 6, p. 490-498 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Electron dispersive X-ray spectroscopy and degradation properties of hyaluronic acid decorated microparticles

Serri, C., Frigione, M., Ruponen, M., Urtti, A., Borzacchiello, A., Biondi, M., Itkonen, J. & Mayol, L., 1 Sep 2019, In : Colloids and Surfaces B: Biointerfaces. 181, p. 896-901 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Enantioselective hyperporous molecularly imprinted thin film polymers

Nilsson, S., Suriyanarayanan, S., Kathiravan, S., Yli-Kauhaluoma, J., Kotiaho, T. & Nicholls, I. A., 23 Oct 2019, In : RSC Advances. 9, 58, p. 33653-33656 4 p.

Research output: Contribution to journalArticleScientificpeer-review

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Enantiospecific pharmacogenomics of fluvastatin

Hirvensalo, P., Tornio, A., Neuvonen, M., Kiander, W., Kidron, H., Paile-Hyvärinen, M., Tapaninen, T., Backman, J. T. & Niemi, M., Sep 2019, In : Clinical Pharmacology and Therapeutics. 106, 3, p. 668-680 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Endocrine activities and adipogenic effects of bisphenol AF and its main metabolite

Skledar, D. G., Carino, A., Trontelj, J., Troberg, J., Distrutti, E., Marchiano, S., Tornasic, T., Zega, A., Finel, M., Fiorucci, S. & Maisic, L. P., Jan 2019, In : Chemosphere. 215, p. 870-880 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Endogenous, cholesterol-activated ATP-dependent transport in membrane vesicles from Spodoptera frugiperda cells

Sjöstedt, N., Salminen, T. A. & Kidron, H., 1 Sep 2019, In : European Journal of Pharmaceutical Sciences. 137, 9 p., 104963.

Research output: Contribution to journalArticleScientificpeer-review

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Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial

Toivo, T., Airaksinen, M., Dimitrow, M., Savela, E., Pelkonen, K., Kiuru, V., Suominen, T., Uunimäki, M., Kivelä, S-L., Leikola, S. & Puustinen, J., 27 Nov 2019, In : BMC Geriatrics. 19, 1, 13 p., 332.

Research output: Contribution to journalArticleScientificpeer-review

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Environmentally-compatible alkyd paints stabilized by wood hemicelluloses

Mikkonen, K. S., Kirjoranta, S., Xu, C., Hemming, J., Pranovich, A., Bhattarai, M., Peltonen, L., Kilpeläinen, P., Maina, N., Tenkanen, M., Lehtonen, M. & Willför, S., Jul 2019, In : Industrial Crops and Products. 133, p. 212-220 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Establishment of an In Vitro-In Vivo Correlation for Melanin Binding and the Extension of the Ocular Half-Life of Small-Molecule Drugs

Jakubiak, P., Cantrill, C., Urtti, A. & Alvarez-Sanchez, R., Dec 2019, In : Molecular Pharmaceutics. 16, 12, p. 4890-4901 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Euryale Ferox Seed-inspired Super-lubricated Nanoparticles for Treatment of Osteoarthritis

Yan, Y., Sun, T., Zhang, H., Ji, X., Sun, Y., Zhao, X., Deng, L., Qi, J., Cui, W., Almeida Santos, H. & Zhang, H., 24 Jan 2019, In : Advanced Functional Materials. 29, 4, 14 p., 1807559.

Research output: Contribution to journalArticleScientificpeer-review

Exploring Light-Sensitive Nanocarriers for Simultaneous Triggered Antibiotic Release and Disruption of Biofilms Upon Generation of Laser-Induced Vapor Nanobubbles

Teirlinck, E., Barras, A., Liu, J., Fraire, J. C., Lajunen, T., Xiong, R., Forier, K., Li, C., Urtti, A., Boukherroub, R., Szunerits, S., De Smedt, S. C., Coenye, T. & Braeckmans, K., May 2019, In : Pharmaceutics. 11, 5, 15 p., 201.

Research output: Contribution to journalArticleScientificpeer-review

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Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

Harloff-Helleberg, S., Fliervoet, L. A. L., Fano, M., Schmitt, M., Antopolski, M., Urtti, A. & Nielsen, H. M., 1 Jan 2019, In : Drug Delivery. 26, 1, p. 532-541 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Extracellular vesicles enhance the targeted delivery of immunogenic oncolytic adenovirus and paclitaxel in immunocompetent mice

Garofalo, M., Villa, A., Rizzi, N., Kuryk, L., Rinner, B., Cerullo, V., Yliperttula, M., Mazzaferro, V. & Ciana, P., 28 Jan 2019, In : Journal of Controlled Release. 294, p. 165-175 11 p.

Research output: Contribution to journalArticleScientificpeer-review

FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis

Turunen, S. P., von Nandelstadh, P., Öhman, T., Gucciardo, E., Seashore-Ludlow, B., Martins, B., Rantanen, V., Li, H., Höpfner, K., Östling, P., Varjosalo, M. & Lehti, K., Dec 2019, In : Cell Death and Differentiation. 26, 12, p. 2577-2593 17 p.

Research output: Contribution to journalArticleScientificpeer-review

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Fluoroquinolone-related adverse events resulting in health service use and costs: A systematic review

Kuula, L. S. M., Viljemaa, K. M., Backman, J. T. & Blom, M., 26 Apr 2019, In : PLoS One. 14, 4, 17 p., 0216029.

Research output: Contribution to journalArticleScientificpeer-review

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Frailty and mortality: an 18-year follow-up study among Finnish community-dwelling older people

Salminen, M., Viljanen, A., Eloranta, S., Viikari, P., Wuorela, M., Vahlberg, T., Isoaho, R., Kivela, S-L., Korhonen, P., Irjala, K., Lopponen, M. & Viikari, L., 25 Oct 2019, In : Aging Clinical and Experimental Research. 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Functionalized Bacterial Cellulose Microparticles for Drug Delivery in Biomedical Applications

Ullah, H., Badshah, M., Rebelo Correia, A. M., Wahid, F., Santos, H. A. & Khan, T., 9 Oct 2019, In : Current Pharmaceutical Design. 25, 34, p. 3692–3701 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Glucocorticoids promote breast cancer metastasis

Obradovic, M. M. S., Hamelin, B., Manevski, N., Couto, J. P., Sethi, A., Coissieux, M-M., Munst, S., Okamoto, R., Kohler, H., Schmidt, A. & Bentires-Alj, M., 28 Mar 2019, In : Nature. 567, 7749, p. 540-+ 21 p.

Research output: Contribution to journalArticleScientificpeer-review

Growth Mode and Carbon Source Impact the Surfaceome Dynamics of Lactobacillus rhamnosus GG

Savijoki, K., Nyman, T. A., Kainulainen, V., Miettinen, I., Siljamäki, P., Fallarero, A., Sandholm, J., Satokari, R. & Varmanen, P., 5 Jun 2019, In : Frontiers in Microbiology. 10, 17 p., 1272.

Research output: Contribution to journalArticleScientificpeer-review

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Harnessing therapeutic viruses as a delivery vehicle for RNA-based therapy

Ylösmäki, L., Polini, B., Carpi, S., Martins, B., Smertina, E., Feola, S., Fusciello, M., Peltonen, K., Nieri, P., Ylösmäki, E. & Cerullo, V., 23 Oct 2019, In : PLoS One. 14, 10, p. e0224072

Research output: Contribution to journalArticleScientificpeer-review

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HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells.

Arasu, U. T., Deen, A. J., Pasonen-Seppänen, S., Heikkinen, S., Lalowski, M., Kärnä, R., Härkönen, K., Mäkinen, P., Lazaro-Ibañez, E., Siljander, P. R-M., Oikari, S., Levonen, A-L. & Rilla, K., 9 Dec 2019, In : Cellular and Molecular Life Sciences. 23 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Heat shock protein 90 is downregulated in calcific aortic disease

Weisell, J., Ohukainen, P., Näpänkangas, J., Ohlmeier, S., BERMANN, U., Peltonen, T., Taskinen, P., Ruskoaho, H. & Rysä, J., 19 Dec 2019, In : BMC Cardiovascular Disorders. 19, 1, 12 p., 306.

Research output: Contribution to journalArticleScientificpeer-review

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Heavy metal content and health risk assessment of commonly patronized herbal medicinal preparations from the Kumasi metropolis of Ghana

Adusei-Mensah, F., Essumang, D. K., Agjei, R. O., Kauhanen, J., Tikkanen-Kaukanen, C. & Ekor, M., 15 Apr 2019, In : Journal of environmental health science & engineering. 17, 2, p. 609-618 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice

Leggiero, E., Labruna, G., Iaffaldano, L., Lombardo, B., Greco, A., Fiorenza, D., Gramanzini, M., Montanaro, D., Baldi, A., Cerullo, V., Sacchetti, L. & Pastore, L., Apr 2019, In : Gene Therapy (Basingstoke). 26, 3-4, p. 121-130 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure

Kalinin, S., Valtari, A., Ruponen, M., Toropainen, E., Kovalenko, A., Nocentini, A., Gureev, M., Dar'in, D., Urtti, A., Supuran, C. T. & Krasavin, M., 1 Nov 2019, In : Bioorganic & Medicinal Chemistry. 27, 21, 8 p., 115086.

Research output: Contribution to journalArticleScientificpeer-review