Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications

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2019

Identification and characterization of approved drugs and drug-like compounds as covalent Escherichia coli ClpP inhibitors

Sassetti, E., Cruz, C. D., Tammela, P., Winterhalter, M., Augustyns, K., Gribbon, P. & Windshügel, B., 1 Jun 2019, In : International Journal of Molecular Sciences. 20, 11, 13 p., 2686.

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Identification of Motor Symptoms Related to Parkinson Disease Using Motion-Tracking Sensors at Home (KAVELI): Protocol for an Observational Case-Control Study

Jauhiainen, M., Puustinen, J., Mehrang, S., Ruokolainen, J., Holm, A., Vehkaoja, A. & Nieminen, H., Mar 2019, In : JMIR Research Protocols. 8, 3, 12 p., 12808.

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Image-Based Investigation: Biorelevant Solubility of α and γ Indomethacin

Štukelj, J., Svanbäck, S., Kristl, J., Strachan, C. J. & Yliruusi, J., 19 Mar 2019, In : Analytical Chemistry. 91, 6, p. 3997-4003 7 p.

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Immobilization of proteolytic enzymes on replica-molded thiol-ene micropillar reactors via thiol-gold interaction

Tähkä, S., Sarfraz, J., Urvas, L., Provenzani, R., Wiedmer, S. K., Peltonen, J., Jokinen, V. & Sikanen, T., Apr 2019, In : Analytical and Bioanalytical Chemistry. 411, 11, p. 2339–2349 11 p.

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Impact of dibenzocyclooctadiene lignans from Schisandra chinensis on the redox status and activation of human innate immune system cells

Kortesoja, M., Karhu, E., Olafsdottir, E. S., Freysdottir, J. & Hanski, L., 1 Feb 2019, In : Free Radical Biology & Medicine. 131, p. 309-317 9 p.

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Implementation of improved postoperative care decreases the mortalit1y rate of operated mice after an abundant 6-hydroxy dopamine lesion of nigrostriatal dopaminergic neurons

Koski, S. K., Leino, S., Rannanpää, S. & Salminen, O., 2019, In : Scandinavian journal of laboratory animal science. 45, 1, p. 1-11 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Improving Group Work Practices in Teaching Life Sciences: Trialogical Learning

Tammeorg, P., Mykkänen, A., Rantamäki, T., Lakkala, M. & Muukkonen, H., Jun 2019, In : Research in Science Education. 49, 3, p. 809-828 20 p.

Research output: Contribution to journalArticleScientificpeer-review

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Influence of Melanin Characteristics on Drug Binding Properties

Jakubiak, P., Lack, F., Thün, J., Urtti, A. & Alvarez-Sanchez, R., Jun 2019, In : Molecular Pharmaceutics. 16, 6, p. 2549-2556 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Influence of strategic planning on product marketing and health service orientation of community pharmacies-A national survey in Finland

Jokinen, L., Puumalainen, I. & Airaksinen, M., May 2019, In : Health Policy. 123, 5, p. 462-467 6 p.

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Inhibition of Hepatitis C replication by targeting the molecular chaperone Hsp90 - synthesis and biological evaluation of 4,5,6,7-tetrahydrobenzo[1,2-d]thiazole derivatives

Lillsunde, K-E. M., Tomašič, T., Schult, P., Lohmann, V., Kikelj, D. & Tammela, P., 5 Feb 2019, In : ChemMedChem : chemistry enabling drug discovery.. 14, 3, p. 334-342 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Inhibition of human carboxylesterases by magnolol: Kinetic analyses and mechanism

Song, Y-Q., Weng, Z-M., Dou, T-Y., Finel, M., Wang, Y-Q., Ding, L-L., Jin, Q., Wang, D-D., Fang, S-Q., Cao, Y-F., Hou, J. & Ge, G-B., 1 Aug 2019, In : Chemico-Biological Interactions. 308, p. 339-349 11 p.

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Inhibition of let-7c Regulates Cardiac Regeneration after Cryoinjury in Adult Zebrafish

Narumanchi, S., Kalervo, K., Perttunen, S., Wang, H., Immonen, K., Kosonen, R., Laine, M., Ruskoaho, H., Tikkanen, I., Lakkisto, P. & Paavola, J., Jun 2019, In : Journal of Cardiovascular Development and Disease. 6, 2, 12 p., 16.

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Inhibition of UGT1A1 by natural and synthetic flavonoids

Liu, X-Y., Lv, X., Wang, P., Ai, C-Z., Zhou, Q-H., Finel, M., Fan, B., Cao, Y-F., Tang, H. & Ge, G-B., 1 Apr 2019, In : International Journal of Biological Macromolecules. 126, p. 653 – 661 9 p.

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Inter-rater reliability of medication error classification in a voluntary patient safety incident reporting system HaiPro in Finland

Holmström, A-R., Järvinen, R., Laaksonen, R., Keistinen, T., Doupi, P. & Airaksinen, M., Jul 2019, In : Research in Social and Administrative Pharmacy. 15, 7, p. 864-872 9 p.

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Intravitreal Pharmacokinetics in Mice: SPECT/CT Imaging and Scaling to Rabbits and Humans

Schmitt, M., Hippeläinen, E., Ravina, M., Arango-Gonzalez, B., Antopolsky, M., Vellonen, K-S., Airaksinen, A. J. & Urtti, A., Oct 2019, In : Molecular Pharmaceutics. 16, 10, p. 4399-4404 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Kävelyä ja jumppaa

Kivelä, S-L., 2019, In : SuPer. 4, p. 32-32 1 p.

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Kohtaavatko saatavuus ja hyödyt? Korvausjärjestelmään hyväksytyt uudet syöpälääkkeet

Koskinen, H., Juntunen, L., Junttila, T. & Kurko, T., 2019, In : Suomen lääkärilehti. 74, 6, p. 327-330 4 p.

Research output: Contribution to journalArticleProfessional

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Large expert-curated database for benchmarking document similarity detection in biomedical literature search

RELISH Consortium, Zhou, Y., Yli-Kauhaluoma, J., Almeida, G. M. D. F., Cardoso, P., Eskelinen, E-L., Helanterä, H., Sillanpää, E., Frilander, M., Korpela, K., Pinto, C., Quinn, G., Tripathi, S. & Zeng, Z., 29 Oct 2019, In : Database-The journal of biological databases and curation. 2019, p. 1-66 66 p., baz085.

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Laser-Activatable CuS Nanodots to Treat Multidrug-Resistant Bacteria and Release Copper Ion to Accelerate Healing of Infected Chronic Nonhealing Wounds

Qiao, Y., Ping, Y., Zhang, H., Zhou, B., Liu, F., Yu, Y., Xie, T., Li, W., Zhong, D., Zhang, Y., Yao, K., Almeida Santos, H. & Zhou, M., 30 Jan 2019, In : ACS Applied Materials & Interfaces. 11, 4, p. 3809–3822 14 p.

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Light-Triggered Cellular Delivery of Oligonucleotides

Kontturi, L-S., van den Dikkenberg, J., Urtti, A., Hennink, W. E. & Mastrobattista, E., Feb 2019, In : Pharmaceutics. 11, 2, 16 p., 90.

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Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules

Valkonen, S., Holopainen, M., Colas, R. A., Impola, U., Dalli, J., Käkelä, R., Siljander, P. R-M. & Laitinen, S., Aug 2019, In : Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1864, 8, p. 1168-1182 15 p.

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Lipid-Polymer Hybrid Nanoparticles for Controlled Delivery of Hydrophilic and Lipophilic Doxorubicin for Breast Cancer Therapy

Tahir, N., Madni, A., Correia, A., Rehman, M., Balasubramanian, V., Khan, M. M. & Santos, H. A., 5 Jul 2019, In : International Journal of Nanomedicine. 14, p. 4961-4974 14 p.

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Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

Felszeghy, S., Viiri, J., Paterno, J. J., Hyttinen, J. M. T., Koskela, A., Chen, M., Leinonen, H., Tanila, H., Kivinen, N., Koistinen, A., Toropainen, E., Amadio, M., Smedowski, A., Reinisalo, M., Winiarczyk, M., Mackiewicz, J., Mutikainen, M., Ruotsalainen, A-K., Kettunen, M., Jokivarsi, K. & 16 others, Sinha, D., Kinnunen, K., Petrovski, G., Blasiak, J., Bjorkoy, G., Koskelainen, A., Skottman, H., Urtti, A., Salminen, A., Kannan, R., Ferrington, D. A., Xu, H., Levonen, A-L., Tavi, P., Kauppinen, A. & Kaarniranta, K., Jan 2019, In : Redox biology. 20, p. 1-12 12 p.

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Loukkaavat sanat ja teot

Kivelä, S-L., 2019, In : SuPer. 5, p. 32-32 1 p.

Research output: Contribution to journalArticleGeneral public

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Mechanism of the Oxidation of Heptafulvenes to Tropones Studied by Online Mass Spectrometry and Density Functional Theory Calculations

Nilsson, S., Henschel, H., Scotti, G., Haapala, M., Kiriazis, A., Boije af Gennäs, G., Kotiaho, T. & Yli-Kauhaluoma, J., 1 Nov 2019, In : Journal of Organic Chemistry. 84, 21, p. 13975-13982 8 p.

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Medication safety risks to be managed in national implementation of automatic substitution of biological medicines: a qualitative study

Tolonen, H. M., Airaksinen, M., Ruokoniemi, P., Hämeen-Anttila, K., Shermock, K. M. & Kurki, P., 2019, In : BMJ Open. 9, 10, 11 p., 032892.

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Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice

Galli, E., Rossi, J., Neumann, T., Andressoo, J-O., Drinda, S. & Lindholm, P., 4 Oct 2019, In : Scientific Reports. 9, 12 p., 14318.

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Metabolic signature of extracellular vesicles depends on the cell culture conditions

Palviainen, M., Saari, H., Kärkkäinen, O., Pekkinen, J., Auriola, S., Yliperttula, M., Puhka, M., Hanhineva, K. & Siljander, P. R-M., 1 Jan 2019, In : Journal of Extracellular Vesicles. 8, 1, 12 p., 1596669.

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Metabolism of Scoparone in Experimental Animals and Humans

Juvonen, R. O., Novak, F., Emmanouilidou, E., Auriola, S., Timonen, J., Heikkinen, A. T., Küblbeck, J., Finel, M. & Raunio, H., Apr 2019, In : Planta Medica. 85, 6, p. 453-464 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Metallization of Organically Modified Ceramics for Microfluidic Electrochemical Assays

Bonabi, A., Tähkä, S., Ollikainen, E., Jokinen, V. & Sikanen, T., Sep 2019, In : Micromachines. 10, 9, 12 p., 605.

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Methyljasmonate Elicitation Increases Terpenoid Indole Alkaloid Accumulation in Rhazya stricta Hairy Root Cultures

Akhgari, A., Laakso, I., Maaheimo, H., Choi, Y. H., Seppänen-Laakso, T., Oksman-Caldentey, K-M. & Rischer, H., Dec 2019, In : Plants. 8, 12, 15 p., 534.

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Moniammatillisen lääkehoidon arviointimallin kehittäminen Järvenpään kotihoidossa

Miettinen, S., Kvarnström, K., Linden-Lahti, C., Holmström, A-R., Tuomi, J., Vuori, K. & Puustinen, J., 2019, In : Dosis : farmaseuttinen aikakauskirja. 35, 3, p. 228-241 14 p.

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Monimuotoinen valmistautuminen

Kivelä, S-L., 2019, In : SuPer. 9, p. 34-34 1 p.

Research output: Contribution to journalArticleGeneral public

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Nanomedicines to tackle myocardial infarction: where are we now and where are we going?

Almeida Ferreira, M. & Santos, H. A., 25 Sep 2019, In : Dosis : farmaseuttinen aikakauskirja. 35, 3, p. 290-298 9 p.

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Neurotrophin receptor Ntrk2b function in the maintenance of dopamine and serotonin neurons in zebrafish

Sahu, M. P., Pazos-Boubeta, Y., Pajanoja, C., Rozov, S., Panula, P. & Castren, E., 14 Feb 2019, In : Scientific Reports. 9, 13 p., 2036.

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New N-phenyl-4,5-dibromopyrrolamides as DNA gyrase B inhibitors

Zidar, N., Macut, H., Tomašič, T., Peterlin Mašič, L., Ilaš, J., Zega, A., Tammela, P. & Kikelj, D., 1 Jun 2019, In : MedChemComm. 10, 6, p. 1007-1017 11 p.

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Nucleic acid delivery to differentiated retinal pigment epithelial cells using cell-penetrating peptide as a carrier

Subia, B., Reinisalo, M., Dey, N., Tavakoli, S., Subrizi, A., Ganguli, M. & Ruponen, M., Jul 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 140, p. 91-99 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Older adults using multi-dose dispensing exposed to risks of potentially inappropriate medications

Bobrova, V., Heinamäki, J., Honkanen, O., Desselle, S., Airaksinen, M. & Volmer, D., Sep 2019, In : Research in Social and Administrative Pharmacy. 15, 9, p. 1102-1106 5 p.

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Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site

Lopes, A., Feola, S., Ligot, S., Fusciello, M., Vandermeulen, G., Préat, V. & Cerullo, V., 10 Jul 2019, In : Journal for Immunotherapy of Cancer. 7, 1, 14 p., 174.

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Optimization of Early Steps in Oncolytic Adenovirus ONCOS-401 Production in T-175 and HYPERFlasks

Kuryk, L., Moller, A-S. W., Vuolanto, A., Pesonen, S., Garofalo, M., Cerullo, V. & Jaderberg, M., 1 Feb 2019, In : International Journal of Molecular Sciences. 20, 3, 15 p., 621.

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ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol

Koponen, A., Arora, A., Takahashi, K., Kentala, H., Kivelä, A. M., Jääskeläinen, E., Peränen, J., Somerharju, P., Ikonen, E., Viitala, T. & Olkkonen, V. M., Mar 2019, In : Biochimie. 158, p. 90-101 12 p.

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Outer-inner Dual Reinforced Micro/Nano Hierarchical Scaffolds for Promoting Osteogenesis

Tang, J., Gu, Y., Zhang, H., Wu, L., Xu, Y., Mao, J., Xin, T., Ye, T., Deng, L., Cui, W., Santos, H. A. & Chen, L., 14 Sep 2019, In : Nanoscale. 11, 34, p. 15794-15803 10 p.

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Overcoming the Pitfalls of Cytochrome P450 Immobilization Through the Use of Fusogenic Liposomes

Kiiski, I. M. A., Pihlaja, T. L. M., Urvas, L. M., Wiedmer, S. K., Witos, J. M., Jokinen, V. P. & Sikanen, T. M., Jan 2019, In : Advanced Biosystems. 3, 1, 6 p., 1800245.

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Peptide Nucleic Acid-Functionalized Adenoviral Vectors Targeting G-Quadruplexes in the P1 Promoter of Bcl-2 Proto-Oncogene: A New Tool for Gene Modulation in Anticancer Therapy

Falanga, A. P., Cerullo, V., Marzano, M., Feola, S., Oliviero, G., Piccialli, G. & Borbone, N., Mar 2019, In : Bioconjugate Chemistry. 30, 3, p. 572-582 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Pharmacy Practice and Education in Finland

Hirvonen, J., Salminen, O., Vuorensola, K., Katajavuori, N., Huhtala, H. & Atkinson, J., 23 Feb 2019, In : Pharmacy. 7, 1, 15 p., 21.

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Photothermal-responsive nanosized hybrid polymersome as versatile therapeutics codelivery nanovehicle for effective tumor suppression

Zhang, H., Cui, W., Qu, X., Wu, H., Qu, L., Zhang, X., Mäkilä, E., Salonen, J., Zhu, Y., Yang, Z., Chen, D., Santos, H. A., Hai, M. & Weitz, D. A., 16 Apr 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 16, p. 7744-7749 6 p.

Research output: Contribution to journalArticleScientificpeer-review

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Pienet tapahtumat – isot ilot

Kivelä, S-L., 2019, In : SuPer. 3, p. 34-34 1 p.

Research output: Contribution to journalArticleGeneral public

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