Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications 1983 2019

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2018
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SDF1 gradient associates with the distribution of c-Kit+ cardiac cells in the heart

Renko, O., Tolonen, A-M., Rysä, J., Magga, J., Mustonen, E., Ruskoaho, H. & Serpi, R., 18 Jan 2018, In : Scientific Reports. 8, 11 p., 1160.

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Sequential Antifouling Surface for Efficient Modulation of the Nanoparticle-Cell Interactions in Protein-Rich Environment

Zhang, F., Kong, L., Liu, D., Li, W., Mäkilä, E., Correia, A., Lindgren, R., Salonen, J., Hirvonen, J. T., Zhang, H., Kros, A. & Almeida Santos, H., May 2018, In : Advanced Therapeutics. 1, 1, p. 1800013 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint

Wei, T., Najmi, S. M., Liu, H., Peltonen, K., Kucerova, A., Schneider, D. A. & Laiho, M., 10 Apr 2018, In : Cell Reports. 23, 2, p. 404-414 11 p.

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Sources of uncertainty in annual global horizontal irradiance data

Urraca, R., Huld, T., Javier Martinez-de-Pison, F. & Sanz-Garcia, A., Aug 2018, In : Solar Energy. 170, p. 873-884 12 p.

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Spin coated chitin films for biosensors and its analysis are dependent on chitin-surface interactions

Casteleijn, M. G., Richardson, D., Parkkila, P. K., Granqvist, N. M., Urtti, A. O. & Viitala, T. J. S., 2018, In : Colloids and Surfaces A: Physicochemical and Engineering Aspects. 539, p. 261-272

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Stapled truncated orexin peptides as orexin receptor agonists

Karhu, L., Weisell, J., Turunen, P. M., Leino, T. O., Pätsi, H., Xhaard, H., Kukkonen, J. P. & Wallén, E. A. A., Apr 2018, In : Peptides. 102, p. 54-60 7 p.

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Structure-based virtual screening of LsrK kinase inhibitors to target quorum sensing

Medarametla, P., Gatta, V., Kajander, T. A., Laitinen, T., Tammela, P. S. M. & Poso, A., 20 Nov 2018, In : ChemMedChem : chemistry enabling drug discovery.. 13, 22, p. 2400-2407 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Synthesis and Antiproliferative Activity of Marine Bromotyrosine Purpurealidin I and Its Derivatives

Bhat, C., Ilina, P., Tilli, I., Vorácova, M., Bruun, T., Barba, V., Hribernik, N., Lillsunde, K-E., Mäki-Lohiluoma, E., Rüffer, T., Lang, H., Yli-Kauhaluoma, J., Kiuru, P. & Tammela, P., 3 Dec 2018, In : Marine Drugs. 16, 12, 26 p., 481.

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Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors

Durcik, M., Tammela, P. S. M., Barančoková, M., Tomašič, T., Ilaš, J., Kikelj, D. & Zidar, N., 22 Jan 2018, In : ChemMedChem : chemistry enabling drug discovery.. 13, 2, p. 186-198 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors

Ahonen, T. J., Rinne, M., Grutschreiber, P., Mätlik, K., Airavaara, M., Schaarschmidt, D., Lang, H., Reiss, D., Xhaard, H., Gaveriaux-Ruff, C., Yli-Kauhaluoma, J. & Moreira, V. M., 10 May 2018, In : European Journal of Medicinal Chemistry. 151, p. 495-507 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Targeted Reinforcement of Macrophage Reprogramming Towards M2 Polarization by IL-4 Loaded Hyaluronic Acid Particles

Shahbazi, M-A., Mahsa Sedighi, M. S., Bauleth-Ramos, T., Krishna Kant, K., Correia, A., Poursina, N., Sarmento, B., Hirvonen, J. T. & Almeida Santos, H., 18 Dec 2018, In : ACS Omega. 3, 12, p. 18444–18455 12 p.

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Temperature-Controlled Interactions between Poly(N-isopropylacrylamide) Mesoglobules Probed by Fluorescence

Fowler, M. A., Duhamel, J., Qiu, X. P., Korchagina, E. & Winnik, F. M., 13 Mar 2018, In : Macromolecules. 51, 5, p. 1946-1956 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Temperature response of aqueous solutions of pyrene end-labeled poly(N-isopropylacrylamide)s probed by steady-state and time-resolved fluorescence

Fowler, M., Duhamel, J., Qiu, X. P., Korchagina, E. & Winnik, F. M., 15 Feb 2018, In : Journal of Polymer Science. Part B, Polymer Physics. 56, 4, p. 308-318 11 p.

Research output: Contribution to journalArticleScientificpeer-review

The effect of light sensitizer localization on the stability of indocyanine green liposomes

Lajunen, T., Nurmi, R., Wilbie, D., Ruoslahti, T., Johansson, N. G., Korhonen, O., Rog, T., Bunker, A., Ruponen, M. & Urtti, A., 28 Aug 2018, In : Journal of Controlled Release. 284, p. 213-223 11 p.

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The effect of lipopolysaccharide (LPS) on inflammatory markers in blood and brain and on behavior in individually-housed pigs

Nordgreen, J., Munsterhjelm, C., Aae, F., Popova, A., Boysen, P., Ranheim, B., Heinonen, M., Raszplewicz, J., Piepponen, P., Lervik, A., Valros, A. & Janczak, A. M., 2 Aug 2018, In : Physiology & Behavior. 195, p. 98-111 14 p.

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The effect of mechanical dry coating with magnesium stearate on flowability and compactibility of plastically deforming microcrystalline cellulose powders

Koskela, J., Morton, D. A. V., Stewart, P. J., Juppo, A. M. & Lakio, S., 15 Feb 2018, In : International Journal of Pharmaceutics. 537, 1-2, p. 64-72 9 p.

Research output: Contribution to journalArticleScientificpeer-review

The microenvironment of proliferative diabetic retinopathy supports lymphatic neovascularization

Gucciardo, E., Loukovaara, S., Korhonen, A., Repo, P., Martins, B., Vihinen, H., Jokitalo, E. & Lehti, K., Jun 2018, In : Journal of Pathology. 245, 2, p. 172-185 14 p.

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The κ-opioid receptor antagonist JDTic decreases ethanol intake in alcohol-preferring AA rats

Uhari-Väänänen, J., Raasmaja, A., Bäckström, P., Oinio, V., Carroll, F. I., Airavaara, M., Kiianmaa, K. & Piepponen, P., May 2018, In : Psychopharmacology. 235, 5, p. 1581-1591 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Tieto lääkityksestä on turvallisen hoidon perusta

Linden-Lahti, C., P. Roine, R., Aaltonen, L-M. & Kinnunen, M., 2018, In : Suomen lääkärilehti. 73, 33, p. 1757-1758 2 p.

Research output: Contribution to journalArticleProfessional

Time-Gated Raman Spectroscopy for Quantitative Determination of Solid-State Forms of Fluorescent Pharmaceuticals

Lipiäinen, T., Pessi, J., Movahedi, P., Koivistoinen, J., Kurki, L., Tenhunen, M., Yliruusi, J., Juppo, A. M., Heikkonen, J., Pahikkala, T. & Strachan, C. J., 3 Apr 2018, In : Analytical Chemistry. 90, 7, p. 4832-4839 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Towards developing a model to study alcohol drinking and craving in female mice housed in automated cages

Koskela, M., Piepponen, T. P., Andressoo, J-O., Võikar, V. & Airavaara, M., 15 Oct 2018, In : Behavioural Brain Research. 352, p. 116-124 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Trends in the long-term use of benzodiazepine anxiolytics and hypnotics: A national register study for 2006 to 2014

Kurko, T., Saastamoinen, L. K., Tuulio-Henriksson, A., Taiminen, T., Tiihonen, J., Airaksinen, M. & Hietala, J., Jun 2018, In : Pharmacoepidemiology and Drug Safety. 27, 6, p. 674-682 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents

Figueiredo, J., Serrano, J. L., Cavalheiro, E., Keurulainen, L., Yli-Kauhaluoma, J. T., Moreira, V. M., Ferreira, S., Domingues, F. C., Silvestre, S. & Almeida, P., 1 Jan 2018, In : European Journal of Medicinal Chemistry. 143, p. 829-842 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Understanding Dissolution and Crystallization with Imaging: A Surface Point of View

Novakovic, D., Isomäki, A., Pleunis, B., Fraser-Miller, S. J., Peltonen, L. J., Laaksonen, T. & Strachan, C. J., Nov 2018, In : Molecular Pharmaceutics. 15, 11, p. 5361-5373 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Understanding Molecular Drivers of Melanin Binding To Support Rational Design of Small Molecule Ophthalmic Drugs

Jakubiak, P., Reutlinger, M., Mattei, P., Schuler, F., Urtti, A. & Alvarez-Sanchez, R., 22 Nov 2018, In : Journal of Medicinal Chemistry. 61, 22, p. 10106-10115 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Universities and smart cities: the challenges to high quality

Anttila, J. & Jussila, K., 17 Jun 2018, In : Total Quality Management & Business Excellence (Print Edition). 29, 9-10, p. 1058-1073 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Unsaturated Fatty Acids Affect Quorum Sensing Communication System and Inhibit Motility and Biofilm Formation of Acinetobacter baumannii

Nicol, M., Alexandre, S., Luizet, J-B., Skogman, M., Jouenne, T., Salcedo, S. P. & De, E., Jan 2018, In : International Journal of Molecular Sciences. 19, 1, 10 p., 214.

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Use of clinical guidelines in cardiology practice in Sudan

Elsadig, H., Weiss, M., Scott, J. & Laaksonen, R., Feb 2018, In : Journal of Evaluation in Clinical Practice. 24, 1, p. 127-134 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Visiopuheesta henkilöstön arkipäivään

Holm, Y. M., Peltola, M. S. & Toikkanen, J., 7 Nov 2018, In : Acatiimi : Professoriliiton, Tieteentekijöiden liiton ja Yliopistonlehtorien liiton lehti. 21, 7, p. 20-21 2 p.

Research output: Contribution to journalArticleProfessional

Open Access
2017

25-Hydroxyvitamin D-3 induces osteogenic differentiation of human mesenchymal stem cells

Lou, Y-R., Toh, T. C., Tee, Y. H. & Yu, H., 17 Feb 2017, In : Scientific Reports. 7, 12 p., 42816.

Research output: Contribution to journalArticleScientificpeer-review

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3D proteochemometrics: using three-dimensional information of proteins and ligands to address aspects of the selectivity of serine proteases

Subramanian, V., Ain, Q. U., Henno, H., Pietilä, L-O., Fuchs, J. E., Prusis, P., Bender, A. & Wohlfahrt, G., May 2017, In : MedChemComm. 8, 5, p. 1037-1045 9 p.

Research output: Contribution to journalArticleScientificpeer-review

A computational study suggests that replacing PEG with PMOZ may increase exposure of hydrophobic targeting moiety

Magarkar, A., Rog, T. & Bunker, A., 30 May 2017, In : European Journal of Pharmaceutical Sciences. 103, p. 128-135 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Aerosolization, Drug Permeation and Cellular Interaction of Dry Powder Pulmonary Formulations of Corticosteroids with Hydroxypropyl-beta-Cyclodextrin as a Solubilizer

Vartiainen, V., Bimbo, L. M., Hirvonen, J., Kauppinen, E. I. & Raula, J., Jan 2017, In : Pharmaceutical Research. 34, 1, p. 25-35 11 p.

Research output: Contribution to journalArticleScientificpeer-review

A miniaturised 3D printed polypropylene reactor for online reaction analysis by mass spectrometry

Scotti, G., Nilsson, S. M. E., Haapala, M., Pöhö, P., Boije af Gennäs, G., Yli-Kauhaluoma, J. & Kotiaho, T., 1 Jun 2017, In : Reaction Chemistry & Engineering. 2, 3, p. 299-303 5 p.

Research output: Contribution to journalArticleScientificpeer-review

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A minitablet formulation made from electrospun nanofibers

Poller, B., Strachan, C., Broadbent, R. & Walker, G. F., May 2017, In : European Journal of Pharmaceutics and Biopharmaceutics. 114, p. 213-220 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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A Multifunctional Nanocomplex for Enhanced Cell Uptake, Endosomal Escape and Improved Cancer Therapeutic Effect

Vingadas Almeida, P., Shahbazi, M-A., Correia, A., Mäkilä, E. M., Kemell, M. L., Salonen, J. & Almeida Santos, H., Jun 2017, In : Nanomedicine. 12, 12, p. 1401-1420 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Analyzing user-generated online content for drug discovery: Development and use of MedCrawler

Helfenstein, A. & Tammela, P., 15 Apr 2017, In : Bioinformatics. 33, 8, p. 1205-1209 5 p.

Research output: Contribution to journalArticleScientificpeer-review

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A Nano-in-Nano Vector: Merging the Best of Polymeric Nanoparticles and Drug Nanocrystals

Liu, D., Rodríguez Bernuz, C., Fan, J., Li, W., Correia, A., Hirvonen, J. T. & Almeida Santos, H., 3 Mar 2017, In : Advanced Functional Materials. 27, 9, 13 p., 1604508.

Research output: Contribution to journalArticleScientificpeer-review

An In-home Advanced Robotic System to Manage Elderly Home-care Patients' Medications: A Pilot Safety and Usability Study

Rantanen, P., Parkkari, T., Leikola, S., Airaksinen, M. & Lyles, A., May 2017, In : Clinical Therapeutics. 39, 5, p. 1054-1061 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library

Gustafsson, M. O., Mohammad, D. K., Ylosmaki, E., Choi, H., Shrestha, S., Wang, Q., Nore, B. F., Saksela, K. & Smith, C. I. E., 3 Apr 2017, In : PLoS One. 12, 4, 13 p., 0174909.

Research output: Contribution to journalArticleScientificpeer-review

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A novel in silico framework to improve MHC-I epitopes and break the tolerance to melanoma

Capasso, C., Magarkar, A., Cervera-Carascon, V., Fusciello, M., Feolaf, S., Muller, M., Garofalo, M., Kuryk, L., Tahtinen, S., Pastore, L., Bunker, A. & Cerullo, V., 2017, In : OncoImmunology. 6, 9, 14 p., 1319028.

Research output: Contribution to journalArticleScientificpeer-review

Antibacterial profiling of abietane-type diterpenoids

Helfenstein, A., Vahermo, M. M. A., Nawrot, D. A., Demirci, F., İşcan, G., Krogerus, S., Yli-Kauhaluoma, J. T., Moreira, V. M. & Tammela, P. S. M., Jan 2017, In : Bioorganic & Medicinal Chemistry. 25, 1, p. 132-137 6 p.

Research output: Contribution to journalArticleScientificpeer-review

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