Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications 1983 2019

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2017

A one-pot synthesis of water soluble highly fluorescent silica nanoparticles

Chandra, S., Beaune, G., Shirahata, N. & Winnik, F., 2017, In : Journal of Materials Chemistry. B. 5, 7, p. 1363-1370 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Apteekin ja lääkärin yhteistyö

Salimäki, J. & Pohjanoksa-Mäntylä, M. K., 17 Feb 2017, In : Suomen lääkärilehti. 2017, 7, p. 444-446 3 p.

Research output: Contribution to journalArticleScientificpeer-review

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Arginine-rich cross-linking peptides with different SV40 nuclear localization signal content as vectors for intranuclear DNA delivery

Bogacheva, M., Egorova, A., Slita, A., Maretina, M., Baranov, V. & Kiselev, A., 1 Nov 2017, In : Bioorganic & Medicinal Chemistry Letters. 27, 21, p. 4781-4785 5 p.

Research output: Contribution to journalArticleScientificpeer-review

A Simple Method for Improving the Spatial Resolution in Infrared Laser Ablation Mass Spectrometry Imaging

Hieta, J-P., Vaikkinen, A., Auno, S., Räikkönen, H., Haapala, M., Scotti, G., Kopra, J., Piepponen, T. & Kauppila, T. J., Jun 2017, In : Journal of the American Society for Mass Spectrometry. 28, 6, p. 1060-1065 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

A structure-activity relationship study of ABCC2 inhibitors

Wissel, G., Deng, F., Kudryavtsev, P., Ghemtio, L., Wipf, P., Xhaard, H. & Kidron, H., 30 May 2017, In : European Journal of Pharmaceutical Sciences. 103, p. 60-69 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Atomic layer deposition-A novel method for the ultrathin coating of minitablets

Hautala, J., Kääriäinen, T., Hoppu, P., Kemell, M., Heinämäki, J., Cameron, D., George, S. & Juppo, A. M., 5 Oct 2017, In : International Journal of Pharmaceutics. 531, 1, p. 47-58 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Attitudes and actions: A survey to assess statin use among Finnish patients with increased risk for cardiovascular events

Silvennoinen, R., Turunen, J. H., Kovanen, P. T., Syvänne, M. & Tikkanen, M. J., Apr 2017, In : Journal of Clinical Lipidology. 11, 2, p. 485-494 10 p.

Research output: Contribution to journalArticleScientificpeer-review

A Versatile Carbonic Anhydrase IX Targeting Ligand-Functionalized Porous Silicon Nanoplatform for Dual Hypoxia Cancer Therapy and Imaging

Janoniene, A., Liu, Z., Baranauskiene, L., Mäkilä, E., Ma, M., Salonen, J., Hirvonen, J., Zhang, H., Petrikaite, V. & Santos, H. A., 26 Apr 2017, In : ACS Applied Materials & Interfaces. 9, 16, p. 13976-13987 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Biological reference materials for extracellular vesicle studies

Valkonen, S., Pol, E. V. D., Böing, A., Yuana, Y., Yliperttula, M., Nieuwland, R., Laitinen, S. & Siljander, P. R-M., 2017, In : European Journal of Pharmaceutics and Biopharmaceutics. 98, p. 4-16 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Biomimetic engineering using cancer cell membranes for designing compartmentalized nanoreactors with organelle-like functions

Balasubramanian, V., Rebelo Correia, A. M., Zhang, H., Fontana, F., Mäkilä, E., Salonen, J., Hirvonen, J. T. & Almeida Santos, H., 21 Mar 2017, In : Advanced Materials. 29, 11, 8 p., 1605375.

Research output: Contribution to journalArticleScientificpeer-review

Bisphenol-A glucuronidation in human liver and breast: identification of UDP-glucuronosyltransferases (UGTs) and influence of genetic polymorphisms

Street, C. M., Zhu, Z., Finel, M. & Court, M. H., 2017, In : Xenobiotica. 47, 1, p. 1-10 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.

Li, X., Wu, Z., An, X., Mei, Q., Bai, M., Hanski, L., Li, X., Ahola, T. & Han, W., 2017, In : eLife. 6, 34 p., e27301.

Research output: Contribution to journalArticleScientificpeer-review

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Boron nitride nanotube-based amphiphilic hybrid nanomaterials for superior encapsulation of hydrophobic cargos

Abu Saleh, D., Niskanen, J., Xue, Y., Golberg, D., Winnik, F. M. & Sosnik, A., Dec 2017, In : Materials today chemistry. 6, p. 45-50 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Brief isoflurane anesthesia regulates striatal AKT-GSK3 beta signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease

Leikas, J. V., Kohtala, S., Theilmann, W., Jalkanen, A. J., Forsberg, M. M. & Rantamaki, T., Aug 2017, In : Journal of Neurochemistry. 142, 3, p. 456-463 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Challenge of paediatric compounding to solid dosage forms sachets and hard capsules - Finnish perspective

Siven, M., Kovanen, S., Siirola, O., Hepojoki, T., Isokirmo, S., Laihanen, N., Eränen, T., Pellinen, J. & Juppo, A. M., May 2017, In : Journal of Pharmacy and Pharmacology. 69, 5, p. 593-602 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of Ionizable Groups' Environments in Proteins and Protein-Ligand Complexes through a Statistical Analysis of the Protein Data Bank

Borrel, A., Camproux, A. & Xhaard, H. G. M., 2017, In : ACS Omega. 2, 10, p. 7359-7374 16 p.

Research output: Contribution to journalArticleScientificpeer-review

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Chemical Profiling and Bioactivity of Body Wall Lipids from Strongylocentrotus droebachiensis

Shikov, A. N., Laakso, I., Pozharitskaya, O. N., Seppänen-Laakso, T., Krishtopina, A. S., Makarova, M. N., Vuorela, H. & Makarov, V., Dec 2017, In : Marine Drugs. 15, 12, 11 p., 365.

Research output: Contribution to journalArticleScientificpeer-review

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Coating Nanoparticles with Plant-Produced Transferrin-Hydrophobin Fusion Protein Enhances Their Uptake in Cancer Cells

Reuter, L. J., Shahbazi, M-A., Mäkilä, E. M., Salonen, J. J., Saberianfar, R., Menassa, R., Santos, H. A., Joensuu, J. J. & Ritala, A., Jun 2017, In : Bioconjugate Chemistry. 28, 6, p. 1639-1648 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Combined Ipsilateral Limb Use Score as an Index of Motor Deficits and Neurorestoration in Parkinsonian Rats

Leikas, J. V., Kaariainen, T. M., Jalkanen, A. J., Lehtonen, M., Rantamaki, T. & Forsberg, M. M., Sep 2017, In : Journal of Neuroscience Research. 95, 9, p. 1858-1870 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Comparison between a novel combination of bioactive glass with clodronate and bioactive glass alone as a treatment for chronic periodontitis

Rosenqvist, K., Gursöy, M., Könönen, E., Gursöy, U. & Juppo, A. M., 2017, In : Journal of Biotechnology & Biomaterials. 7, 3, 6 p., 265.

Research output: Contribution to journalArticleScientificpeer-review

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Comparison of liposomal drug formulations for transdermal iontophoretic drug delivery

Malinovskaja-Gomez, K., Espuelas, S., Garrido, M. J., Hirvonen, J. & Laaksonen, T., 30 Aug 2017, In : European Journal of Pharmaceutical Sciences. 106, p. 294-301 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Competence-Based Pharmacy Education in the University of Helsinki

Katajavuori, N., Salminen, O., Vuorensola, K., Huhtala, H., Vuorela, P. & Hirvonen, J., 2017, In : Pharmacy. 5, 2, 29.

Research output: Contribution to journalArticleScientificpeer-review

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Convection-Driven Pull-Down Assays in Nanoliter Droplets Using Scaffolded Aptamers

Qu, X., Zhang, H., Chen, H., Aldalbahi, A., Li, L., Tian, Y., Weitz, D. A. & Pei, H., 21 Mar 2017, In : Analytical Chemistry. 89, 6, p. 3468-3473 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Core/Shell Nanocomposites Produced by Superfast Sequential Microfluidic Nanoprecipitation

Liu, D., Zhang, H., Cito, S., Fan, J., Mäkilä, E., Salonen, J., Hirvonen, J., Sikanen, T. M., Weitz, D. A. & Santos, H. A., Feb 2017, In : Nano Letters. 17, 2, p. 606-614 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Current trends in drug safety research : shifting towards methodology applying real world data

Inácio, P., 2017, In : Dosis. 33, 3, p. 216-224 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Dampened Amphetamine-Stimulated Behavior and Altered Dopamine Transporter Function in the Absence of Brain GDNF

Kopra, J. J., Panhelainen, A., af Bjerken, S., Porokuokka, L. L., Varendi, K., Olfat, S., Montonen, H., Piepponen, T. P., Saarma, M. & Andressoo, J-O., 8 Feb 2017, In : Journal of Neuroscience. 37, 6, p. 1581-1590 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Depolarizing γ-aminobutyric acid contributes to glutamatergic network rewiring in epilepsy

Kourdougli, N., Pellegrino, C., Renko, J-M., Khirug, S., Chazal, G., Kukko-Lukjanov, T-K., Lauri, S. E., Gaiarsa, J-L., Zhou, L., Peret, A., Castrén, E., Tuominen, R. K., Crepel, V. & Rivera Baeza, C., Feb 2017, In : Annals of Neurology. 81, 2, p. 251-265 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors

Tomašič, T., Mirt, M., Barančoková, M., Ilaš, J., Zidar, N., Tammela, P. S. M. & Kikelj, D., 1 Jan 2017, In : Bioorganic & Medicinal Chemistry. 25, 1, p. 338-349 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Design, Synthesis and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors

Cotman, A., Trampuž, M., Brvar, M., Kikelj, D., Ilaš, J., Peterlin-Mašič, L., Montalvao, S. I. G. H., Tammela, P. S. M. & Frlan, R., Aug 2017, In : Archiv der Pharmazie : Chemistry in life sciences. 350, 8, 16 p., 1700087 .

Research output: Contribution to journalArticleScientificpeer-review

Development and Optimization of Methotrexate-Loaded Lipid-Polymer Hybrid Nanoparticles for Controlled Drug Delivery Applications

Tahir, N., Madni, A., Balasubramanian, V., Rehman, M., Rebelo Correia, A. M., Muhammad Kashif, P., Mäkilä, E., Salonen, J. & Almeida Santos, H., 25 Nov 2017, In : International Journal of Pharmaceutics. 533, 1, p. 156–168 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Dicer and microRNAs protect adult dopamine neurons

Chmielarz, P., Konovalova, J., Najam, S. S., Alter, H., Piepponen, T. P., Erfle, H., Sonntag, K. C., Schutz, G., Vinnikov, I. A. & Domanskyi, A., 25 May 2017, In : Cell Death and Disease. 8, 5, 9 p., 2813.

Research output: Contribution to journalArticleScientificpeer-review

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Difference in the core-shell dynamics of polyethyleneimine and poly(L-lysine) DNA polyplexes

Vuorimaa-Laukkanen, E., Lisitsyna, E. S., Ketola, T-M., Morin-Picardat, E., Liang, H., Hanzlikova, M. & Yliperttula, M., 30 May 2017, In : European Journal of Pharmaceutical Sciences. 103, SI, p. 122-127 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Differentially cleaving peptides as a strategy for controlled drug release in human retinal pigment epithelial cells

Bhattacharya, M., Sarkhel, S., Peltoniemi, J., Broadbridge, R., Tuomainen, M., Auriola, S. & Urtti, A., 10 Apr 2017, In : Journal of Controlled Release. 251, p. 37-48 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Difficulties in administration of oral medication formulations to pet cats: an e-survey of cat owners

Sivén, M., Savolainen, S., Räntilä, S., Männikkö, S., Vainionpää, M., Airaksinen, S., Raekallio, M., Vainio, O. & Juppo, A. M., 10 Mar 2017, In : Veterinary Record. 180, 10, 6 p., 250.

Research output: Contribution to journalArticleScientificpeer-review

Direct analysis of Peucedanum palustre samples by desorption atmospheric pressure photoionization-mass spectrometry

Yrjönen, T., Vuorela, H. & Kauppila, T. J., Jun 2017, In : Phytochemistry Letters. 20, p. 49-53 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Discovery of Small Molecules Targeting the Synergy of Cardiac Transcription Factors GATA4 and NKX2-5

Välimäki, M. J., Tölli, M. A., Kinnunen, S. M., Aro, J., Serpi, R., Pohjolainen, L., Talman, V., Poso, A. & Ruskoaho, H. J., 28 Sep 2017, In : Journal of Medicinal Chemistry. 60, 18, p. 7781-7798 18 p.

Research output: Contribution to journalArticleScientificpeer-review

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Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors

Jakopin, Z., Ilas, J., Barancokova, M., Brvar, M., Tammela, P., Dolenc, M. S., Tomasic, T. & Kikelj, D., 21 Apr 2017, In : European Journal of Medicinal Chemistry. 130, p. 171-184 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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Distinct prostate cancer-related mRNA cargo in extracellular vesicle subsets from prostate cell lines

Lazaro-Ibanez, E., Lunavat, T. R., Jang, S. C., Escobedo-Lucea, C., Oliver-De La Cruz, J., Siljander, P., Lotvall, J. & Yliperttula, M., 1 Feb 2017, In : BMC Cancer. 17, 11 p., 92.

Research output: Contribution to journalArticleScientificpeer-review

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Distribution, properties, and inhibitor sensitivity of zebrafish catechol-O-methyl transferases (COMT)

Semenova, S., Rozov, S. & Panula, P., 1 Dec 2017, In : Biochemical Pharmacology. 145, p. 147-157 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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DNA sequences within glioma-derived extracellular vesicles can cross the intact blood-brain barrier and be detected in peripheral blood of patients

Garcia-Romero, N., Carrion-Navarro, J., Esteban-Rubio, S., Lazaro-Ibanez, E., Peris-Celda, M., Alonso, M. M., Guzman-De-Villoria, J., Fernandez-Carballal, C., Ortiz de Mendivil, A., Garcia-Duque, S., Escobedo-Lucea, C., Prat-Acin, R., Belda-Iniesta, C. & Ayuso-Sacido, A., 3 Jan 2017, In : Oncotarget. 8, 1, p. 1416-1428 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Dopaminergic modulation of reward-guided decision making in alcohol-preferring AA rats

Oinio, V., Bäckström, P., Uhari-Väänänen, J., Raasmaja, A., Piepponen, T. & Kiianmaa, K., 30 May 2017, In : Behavioural Brain Research. 326, p. 87-95 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Drug-loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling

Ferreira, M. P. A., Ranjan, S., Kinnunen, S., Correia, A., Talman, V., Mäkilä, E., Barrios-Lopez, B., Kemell, M., Balasubramanian, V., Salonen, J., Hirvonen, J., Ruskoaho, H., Airaksinen, A. J. & Santos, H. A., 6 Sep 2017, In : Small. 13, 33, 14 p., 1701276.

Research output: Contribution to journalArticleScientificpeer-review

Drug survival on tumour necrosis factor inhibitors in patients with rheumatoid arthritis in Finland

Aaltonen, K. J., Joensuu, J. T., Pirilä, L., Kauppi, M., Uutela, T., Varjolahti-Lehtinen, T., Yli-Kerttula, T., Isomäki, P., Nordström, D. & Sokka, T., 2017, In : Scandinavian Journal of Rheumatology. 46, 5, p. 359-363 5 p.

Research output: Contribution to journalArticleScientificpeer-review

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Early career researchers want Open Science: Comment

Farnham, A., Kurz, C., Öztürk, M. A., Solbiati, M., Myllyntaus, O., Meekes, J., Pham, T. M., Paz, C., Langiewicz, M., Kanninen, L., Agbemabiese, C., Tugce Guler, A., Durieux, J., Jasim, S., Viessmann, O., Frattini, S., Yembergenova, C., Benito, C. M., Porte, M., Grangeray-Vilmint, A. & 5 othersCuriel, R. P., Rehncrona, C., Malas, T., Esposito, F. & Hettne, K., 15 Nov 2017, In : Genome Biology. 18, 4 p., 221.

Research output: Contribution to journalArticleScientific

Open Access
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Effectiveness and drug survival of TNF-inhibitors in the treatment of psoriatic arthritis: A prospective cohort study

Aaltonen, K., Heinonen, A., Joensuu, J., Parmanne, P., Karjalainen, A., Varjolahti-Lehtinen, T., Uutela, T., Puurtinen-Vilkki, M., Arstila, L., Blom, M., Sokka, T. & Nordström, D., Jun 2017, In : Seminars in Arthritis and Rheumatism. 46, 6, p. 732-739 8 p.

Research output: Contribution to journalArticleScientificpeer-review

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Effect of piroxicam on lipid membranes: Drug encapsulation and gastric toxicity aspects

Wilkosz, N., Rissanen, S., Cyza, M., Szybka, R., Nowakowska, M., Bunker, A., Rog, T. & Kepczynski, M., 30 Mar 2017, In : European Journal of Pharmaceutical Sciences. 100, p. 116-125 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of solvent quality and chain density on normal and frictional forces between electrostatically anchored thermoresponsive diblock copolymer layers

An, J., Liu, X., Dedinaite, A., Korchagina, E., Winnik, F. M. & Claesson, P. M., 1 Feb 2017, In : Journal of Colloid and Interface Science. 487, p. 88-96 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Effects of Membrane PEGylation on Entry and Location of Antifungal Drug Itraconazole and Their Pharmacological Implications

Dzieciuch-Rojek, M., Poojari, C., Bednar, J., Bunker, A., Kozik, B., Nowakowska, M., Vattulainen, I., Wydro, P., Kepczynski, M. & Rog, T., Apr 2017, In : Molecular Pharmaceutics. 14, 4, p. 1057-1070 14 p.

Research output: Contribution to journalArticleScientificpeer-review