Faculty of Pharmacy

  • Viikinkaari 5

    HELSINKI

    Finland

Publications 1983 2019

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2017

Refolding of Aggregation-Prone ScFv Antibody Fragments Assisted by Hydrophobically Modified Poly(sodium acrylate) Derivatives

Martin, N., Costa, N., Wien, F., Winnik, F. M., Ortega, C., Herbet, A., Boquet, D. & Tribet, C., Feb 2017, In : Macromolecular Bioscience. 17, 2, 12 p., 1600213.

Research output: Contribution to journalArticleScientificpeer-review

Regioselective Benzylic Oxidation of Aromatic Abietanes: Application to the Semisynthesis of the Naturally Occurring Picealactones A, B and C

Kolsi, L. E., Krogerus, S., Brito, V., Rüffer, T., Lang, H., Yli-Kauhaluoma, J. T., Silvestre, S. & Moreira, V. M., 22 Aug 2017, In : ChemistrySelect. 2, 24, p. 7008-7012 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Rekisteritutkimus ja biopankit: kahdesta huipusta yhdeksi kärjeksi

Elsilä, L., May 2017, In : Proviisorilehti. 2, p. 16-17 2 p.

Research output: Contribution to journalArticleProfessional

Open Access

Repeated brief isoflurane anesthesia during early postnatal development produces negligible changes on adult behavior in male mice

Rosenholm, M., Paro, E., Antila, H., Voikar, V. & Rantamäki, T., 5 Apr 2017, In : PLoS One. 12, 4, 16 p., 0175258.

Research output: Contribution to journalArticleScientificpeer-review

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Screening bioactivity and bioactive constituents of Nordic unifloral honeys

Salonen, A., Virjamo, V., Tammela, P. S. M., Fauch, L. & Julkunen-Tiitto, R., 18 May 2017, In : Food Chemistry. 237, p. 214-224 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Severe neurodegenerative disease in brothers with homozygous mutation in POLR1A

Kara, B., Koroglu, C., Peltonen, K., Steinberg, R. C., Genc, H. M., Holtta-Vuori, M., Guven, A., Kanerva, K., Kotil, T., Solakoglu, S., Zhou, Y., Olkkonen, V. M., Ikonen, E., Laiho, M. & Tolun, A., Feb 2017, In : European Journal of Human Genetics. 25, 3, p. 315-323 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Simultaneous Comparison of Two Roller Compaction Techniques and Two Particle Size Analysis Methods

Saarinen, T., Antikainen, O. & Yliruusi, J., Nov 2017, In : AAPS PharmSciTech. 18, 8, p. 3198-3207 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Small-angle X-ray scattering from the concentrated bulk phase separated from an amphiphilic block-copolymer solution

Kondo, M., Takahashi, R., Qiu, X-P., Winnik, F. M., Terao, K. & Sato, T., Apr 2017, In : Polymer Journal. 49, 4, p. 385-389 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Solid Sampling with a Diode Laser for Portable Ambient Mass Spectrometry

Yung, Y. P., Wickramasinghe, R., Vaikkinen, A., Kauppila, T. J., Veryovkin, I. V. & Hanley, L., 18 Jul 2017, In : Analytical Chemistry. 89, 14, p. 7297-7301 5 p.

Research output: Contribution to journalArticleScientificpeer-review

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Solunulkoiset vesikkelit - isoja asioita pienessä paketissa

Mari, P., Valkonen, S., Lindelöf, A., Puhka, M. & Siljander, P., 2017, In : Kliin lab : kliinisen laboratorioalan julkaisu : SKKY:n jäsenlehti.. 34, 4, p. 75-79 5 p.

Research output: Contribution to journalArticleProfessional

Sponge Spray-Reaching New Dimensions of Direct Sampling and Analysis by MS

Hecht, M., Evard, H., Takkis, K., Veigure, R., Aro, R., Lohmus, R., Herodes, K., Leito, I. & Kipper, K., 7 Nov 2017, In : Analytical Chemistry. 89, 21, p. 11592-11597 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Stability and binding affinity of DNA/chitosan complexes by polyanion competition

Ma, P. L., Lavertu, M., Winnik, F. M. & Buschmann, M. D., 15 Nov 2017, In : Carbohydrate Polymers. 176, p. 167-176 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Stability optimization of microbial surface-enhanced Raman spectroscopy detection with immunomagnetic separation beads

Uusitalo, S., Kögler, M., Välimaa, A-L., Petäjä, J., Kontturi, V., Siitonen, S., Laitinen, R., Kinnunen, M., Viitala, T. & Hiltunen, J., Mar 2017, In : Optical Engineering. 56, 3, 7 p., 037102.

Research output: Contribution to journalArticleScientificpeer-review

Structural Isosteres of Phosphate Groups in the Protein Data Bank

Zhang, Y., Borrel, A., Ghemtio, L., Regad, L., Boije af Gennäs, G., Camproux, A-C., Yli-Kauhaluoma, J. & Xhaard, H., Mar 2017, In : Journal of Chemical Information and Modeling. 57, 3, p. 499-516 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Suberin Fatty Acids from Outer Birch Bark: Isolation and Physical Material Characterization

Heinämäki, J., Pirttimaa, M. M., Alakurtti, S., Pitkänen, H. P., Kanerva, H., Hulkko, J., Paaver, U., Aruväli, J., Yliruusi, J. & Kogermann, K., Apr 2017, In : Journal of Natural Products. 80, 4, p. 916-924 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Supersaturating drug delivery systems: The potential of co-amorphous drug formulations

Laitinen, R., Löbmann, K., Grohganz, H., Priemel, P., Strachan, C. J. & Rades, T., 30 Oct 2017, In : International Journal of Pharmaceutics. 532, 1, p. 1-12 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Surface Modification of Acetaminophen Particles by Atomic Layer Deposition

Kääriäinen, T. O., Kemell, M. L., Vehkamäki, M. J., Kääriäinen, M-L., Correia, A., Almeida Santos, H., Marques dos Santos Bimbo, L. M., Hirvonen, J. T., Hoppu, P., George, S. M., Cameron, D. C., Ritala, M. K. & Leskelä, M. A., 15 Jun 2017, In : International Journal of Pharmaceutics. 525, 1, p. 160–174 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Switching maintenance infliximab therapy to biosimilar infliximab in inflammatory bowel disease patients

Eberl, A., Huoponen, S., Pahikkala, T., Blom, M., Arkkila, P. & Sipponen, T., 2017, In : Scandinavian Journal of Gastroenterology. 52, 12, p. 1348-1353 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Synthesis and biological evaluation of 8-hydroxy2,7-naphthyridin-2-ium salts as novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)

Schiedel, M., Fallarero, A., Luise, C., Sippl, W., Vuorela, P. & Jung, M., 2017, In : MedChemComm. 8, 2, p. 465-470 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel KV10.1

Moreels, L., Bhat, C., Voráčová, M., Peigneur, S., Goovaerts, H., Mäki-Lohiluoma, E., Zahed, F., Pardo, L. A., Yli-Kauhaluoma, J. T., Kiuru, P. S. & Tytgat, J., 8 Dec 2017, In : PLoS One. 12, 12, 18 p., 0188811.

Research output: Contribution to journalArticleScientificpeer-review

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Targeting Tumor-Associated Exosomes with Integrin-Binding Peptides

Carney, R. P., Hazari, S., Rojalin, T., Knudson, A., Gao, T., Tang, Y., Liu, R., Viitala, T., Yliperttula, M. & Lam, K. S., May 2017, In : Advanced Biosystems. 1, 5, 12 p., 1600038.

Research output: Contribution to journalArticleScientificpeer-review

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Tc-99m-labeled glimepiride as a tracer for targeting pancreatic beta-cells mass: preparation and preclinical evaluation

El-Kawy, O. A. & Garcia-Horsman, J. A., Dec 2017, In : Journal of Radioanalytical and Nuclear Chemistry. 314, 3, p. 2539-2550 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Tc-99m-roxifiban: a potential molecular imaging agent for the detection and localization of acute venous thrombosis

El-Kawy, O. A. & Garcia-Horsman, J. A., Mar 2017, In : Journal of Radioanalytical and Nuclear Chemistry. 311, 3, p. 1719-1728 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Tempaistaan juhlavuoden kunniaksi

Yli-Kauhaluoma, J. T., 11 Oct 2017, In : Kemia - Kemi. 44, 6, p. 22 1 p.

Research output: Contribution to journalArticleProfessional

Open Access

The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers

Semjonov, K., Kogermann, K., Laidmae, I., Antikainen, O., Strachan, C. J., Ehlers, H., Yliruusi, J. & Heinämäki, J., 15 Jan 2017, In : European Journal of Pharmaceutical Sciences. 97, p. 237-246 10 p.

Research output: Contribution to journalArticleScientificpeer-review

The Impact of Porous Silicon Nanoparticles on Human Cytochrome P450 Metabolism in Human Liver Microsomes In Vitro

Ollikainen, E., Liu, D., Kallio, A., Mäkilä, E., Zhang, H., Salonen, J., Almeida Santos, H. & Sikanen, T. M., 15 Jun 2017, In : European Journal of Pharmaceutical Sciences. 104, p. 124–132 9 p.

Research output: Contribution to journalArticleScientificpeer-review

The value of patient reporting to the pharmacovigilance system: a systematic review

Inácio, P., Cavaco, A. & Airaksinen, M., Feb 2017, In : British Journal of Clinical Pharmacology. 83, 2, p. 227-246 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Thiol-ene micropillar array electrospray ionization platform for zeptomole level bioanalysis

Lipponen, K., Tähkä, S., Sikanen, T., Jokinen, V., Tatikonda, A., Franssila, S., Kostiainen, R. & Kotiaho, T., 21 Jul 2017, In : Analyst. 142, 14, p. 2552-2557 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Three out of four disease-modifying anti-rheumatic drug-naive rheumatoid arthritis patients meet 28-joint Disease Activity Score remission at 12months: results from the FIN-ERA cohort

Rannio, T., Asikainen, J., Hannonen, P., Yli-Kerttula, T., Ekman, P., Pirilä, L., Kuusalo, L., Mali, M., Puurtinen-Vilkki, M., Kortelainen, S., Paltta, J., Taimen, K., Kauppi, M., Laiho, K., Nyrhinen, S., Makinen, H., Isomaki, P., Uotila, T., Aaltonen, K., Kautiainen, H. & 1 othersSokka, T., 2017, In : Scandinavian Journal of Rheumatology. 46, 6, p. 425-431 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Time-Resolved Fluorescence Spectroscopy Reveals Fine Structure and Dynamics of Poly(L-lysine) and Polyethylenimine Based DNA Polyplexes

Lisitsyna, E. S., Ketola, T-M., Morin-Picardat, E., Liang, H., Hanzlikova, M., Urtti, A., Yliperttula, M. & Vuorimaa-Laukkanen, E., 7 Dec 2017, In : Journal of Physical Chemistry B. 121, 48, p. 10782-10792 11 p.

Research output: Contribution to journalArticleScientificpeer-review

TiO2 Photocatalysis-DESI-MS Rotating Array Platform for High-Throughput Investigation of Oxidation Reactions

Ruokolainen, M., Miikkulainen, V., Ritala, M., Sikanen, T., Kotiaho, T. & Kostiainen, R., 7 Nov 2017, In : Analytical Chemistry. 89, 21, p. 11214-11218 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment

Kuryk, L., Vassilev, L., Ranki, T., Hemminki, A., Karioja-Kallio, A., Levälampi, O., Vuolanto, A., Cerullo, V. & Pesonen, S., 10 Aug 2017, In : PLoS One. 12, 8, 15 p., 0182715.

Research output: Contribution to journalArticleScientificpeer-review

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Transcription factor PEX1 modulates extracellular matrix turnover through regulation of MMP-9 expression

Acosta, A. J., Rysä, J., Szabo, Z., Moilanen, A-M., Komati, H., Nemer, M. & Ruskoaho, H., Feb 2017, In : Cell and Tissue Research. 367, 2, p. 369-385 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Transition-Metal-Doped NIR-Emitting Silicon Nanocrystals

Chandra, S., Masuda, Y., Shirahata, N. & Winnik, F. M., 22 May 2017, In : Angewandte Chemie (International Edition). 56, 22, p. 6157-6160 4 p.

Research output: Contribution to journalArticleScientificpeer-review

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Transmembrane Domain Single-Nucleotide Polymorphisms Impair Expression and Transport Activity of ABC Transporter ABCG2

Sjöstedt, N., van den Heuvel, J. J. M. W., Koenderink, J. B. & Kidron, H., Aug 2017, In : Pharmaceutical Research. 34, 8, p. 1626-1636 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Two cations, two mechanisms: interactions of sodium and calcium with zwitterionic lipid membranes

Javanainen, M., Melcrova, A., Magarkar, A., Jurkiewicz, P., Hof, M., Jungwirth, P. & Martinez-Seara, H., 14 May 2017, In : Chemical Communications. 53, 39, p. 5380-5383 4 p.

Research output: Contribution to journalArticleScientificpeer-review

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UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?

Troberg, J., Järvinen, E., Ge, G-B., Yang, L. & Finel, M., Sep 2017, In : Molecular Pharmaceutics. 14, 9, p. 2875-2883 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Ultrasonic Processing Technique as a Green Preparation Approach for Diacerein-Loaded Niosomes

Khan, M. I., Madni, A., Hirvonen, J. & Peltonen, L., Jul 2017, In : AAPS PharmSciTech. 18, 5, p. 1554-1563 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Understanding quality: conceptualization of the fundamental concepts of quality

Anttila, J. & Jussila, K., 2017, In : International journal of quality and service sciences. 9, 3-4, p. 251-268 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Uusien biologisesti aktiivisten betuliini- johdannaisten valmistaminen

Haavikko, R., 2017, In : Dosis. 33, 2, p. 139-158 20 p.

Research output: Contribution to journalArticleProfessional

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Uusi NRAS-mutaatiota kantava MUG-Mel2 -melanoomasolulinja

Koivuniemi, R. J., Nov 2017, In : Best Practice Ihotaudit. Mar 2017

Research output: Contribution to journalArticleProfessional

"Vaaralliset" lääkkeet

Schepel, L., Linden-Lahti, C., Kinnunen, M., Roine, R. P. & Aaltonen, L-M., 2017, In : Suomen lääkärilehti. 72, 49, p. 2906-2908 3 p.

Research output: Contribution to journalArticleProfessional

Open Access
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What is medicinal chemistry? – Demystifying a rapidly evolving discipline!

Moreira, V. M., 2017, (Submitted) In : MedChemComm. 9

Research output: Contribution to journalArticleProfessional

YAP regulates cell mechanics by controlling focal adhesion assembly

Nardone, G., La Cruz, J. O-D., Vrbsky, J., Martini, C., Pribyl, J., Skladal, P., Pesl, M., Caluori, G., Pagliari, S., Martino, F., Maceckova, Z., Hajduch, M., Sanz-Garcia, A., Pugno, N. M., Stokin, G. B. & Forte, G., 15 May 2017, In : Nature Communications. 8, 13 p., 15321.

Research output: Contribution to journalArticleScientificpeer-review

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2016

Aasialaisesta lääkintäperinteestä Euroopan farmakopeaan: Schisandra chinensis -marjauutteen vanhat ja uudet käyttökohteet

Hanski, L. L., Nov 2016, In : Dosis. 2, p. 151-159 9 p.

Research output: Contribution to journalArticleProfessional

Abietane-Type Diterpenoid Amides with Highly Potent and Selective Activity against Leishmania donovani and Trypanosoma cruzi

Pirttimaa, M., Nasereddin, A., Kopelyanskiy, D., Kaiser, M., Yli-Kauhaluoma, J., Oksman-Caldentey, K-M., Brun, R., Jaffe, C. L., Moreira, V. M. & Alakurtti, S., Feb 2016, In : Journal of Natural Products. 79, 2, p. 362-368 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Accumbal µ-opioid receptors modulate ethanol intake in alcohol-preferring Alko Alcohol rats

Uhari-Väänänen, J. K., Raasmaja, A. I., Bäckström, P., Oinio, V., Airavaara, M. T., Piepponen, P. & Kiianmaa, K., Oct 2016, In : Alcoholism: Clinical and Experimental Research. 40, 10, p. 2114-2123 10 p.

Research output: Contribution to journalArticleScientificpeer-review