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2020

Regioselective Prenylation of Peptide Termini during the Biosynthesis of the Natural Product Muscoride

Mattila, A., Andsten, R-M., Jumppanen, M., Assante, M., Jokela, J., Wahlsten, M., Mikula, K. M., Gugger, M., Koskela, H., Sivonen, K., Yli-Kauhaluoma, J., Iwai, H. & Fewer, D. P., Jan 2020, In : Marine Drugs. 18, 1, 1 p., 40.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2019

A potent partial agonist of PKC orients in membranes like the biological activator diacylglycerol

Lautala, S., Koivuniemi, A., Kulig, W., Rog, T., Talman, V., Tuominen, R. & Bunker, A., Jul 2019, In : European Biophysics Journal. 48, p. S122-S122 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling

Murumagi, A., Ungureanu, D., Khan, S., Hirasawa, A., Arjama, M., Valimaki, K., Mikkonen, P., Niininen, W., Kumar, A., Eldfors, S., Pellinen, T., Pietiainen, V., Magi, A., Koivisto-Korander, R., Tapper, J., Loukovaara, M., Aittokallio, T., Butzow, R. & Kallioniemi, O., Jul 2019, In : Cancer Research. 79, 13, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Drug screening and molecular profiling identifies INKA1 as a predictive biomarker for sensitivity to MAPK inhibition-antimitotic combination treatment in pancreatic ductal adenocarcinoma

Gautam, P., Vaha-Koskela, M., Tomlinson, M., Cox, A. D., Der, C. J., Aittokallio, T. & Wennerberg, K., Dec 2019, In : Molecular Cancer Therapeutics. 18, 12 suppl., 2 p., A137.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

GENETICS OF HUMAN PLASMA LIPIDOME AND ITS LINK TO DISEASES SUSCEPTIBILITY

SK Serv, T FinnGen Project, Tabassum, R., Rämö, J. T., Ripatti, P., Koskela, J. T., Kurki, M., Karjalainen, J., Palta, P., Hassan, S., Nunez-Fontarnau, J., Kiiskinen, T. T. J., Soderlund, S., Matikainen, N., Laivuori, H., Havulinna, A. S., Salomaa, V., Pirinen, M., Jauhiainen, M., Daly, M. J. & 3 others, Palotie, A., Taskinen, M. R. & Ripatti, S., Aug 2019, In : Atherosclerosis. 287, p. E14-E15 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Multivariate GWAS of inflammatory markers reveals novel disease associations

Ruotsalainen, S. E., Partanen, J., Surakka, I., Pirinen, M., Salomaa, V., Salmi, M., Jalkanen, S., Daly, M. J., Ripatti, S. & Koskela, J., 10 Oct 2019, In : European Journal of Human Genetics. 27, 11, p. 1156-1157 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

POLYGENIC HYPERLIPIDEMIA INCREASES CORONARY ARTERY DISEASE RISK IN THE UK BIOBANK

Ripatti, P., Ramo, J. T., Soderlund, S., Surakka, I., Havulinna, A. S., Widen, E., Palta, P., Freimer, N. B., Salomaa, V., Pirinen, M., Palotie, A., Taskinen, M. R. & Ripatti, S., Aug 2019, In : Atherosclerosis. 287, p. E92-E92 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The catalytic mechanism of MB-COMT: new drug design paradigm?

Bunker, A., Rog, T., Magarkar, A., Parkkila, P., Lajunen, T., Mobarak, E., Cramariuc, O., Licari, G. & Vauthey, E., Jul 2019, In : European Biophysics Journal. 48, p. S63-S63 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2018

Combined transcriptomics, proteomics and metabolomics analysis identifies metabolic pathways associated with the loss of cardiac regeneration

Talman, V., Teppo, J., Poho, P., Movahedi, P., Vaikkinen, A., Pahikkala, T., Kotiaho, T., Kostiainen, R., Varjosalo, M. & Ruskoaho, H., Apr 2018, In : Cardiovascular Research. 114, p. S22-S23 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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Efficient fine-mapping to identify causal genetic variants and quantify their contribution to complex phenotypes

Benner, C., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., Oct 2018, In : Genetic Epidemiology. 42, 7, p. 688-689 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Establishment and high-throughput drug testing of multiple patient-derived cells from each renal cancer; intratumor heterogeneity of drug response and implications for precision medicine

Saeed, K., Ojamies, P., Pellinen, T., Eldfors, S., Turkki, R., Lundin, J., Nisen, H., Jarvinen, P., Taari, K., af Hallstrom, T., Rannikko, A., Mirtti, T., Kallioniemi, O. & Ostling, P., Jul 2018, In : Cancer Research. 78, 13, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Melatonin receptor type 1A gene linked to intolerance to shift work and Alzheimer's disease in old age

Sulkava, S., Muggalla, P., Sulkava, R., Ollila, H. M., Peuralinna, T., Myllykangas, L., Helisalmi, S., Soininen, H., Polvikoski, T., Hiltunen, M., Tienari, P. J., Huttunen, H. J. & Paunio, T., Sep 2018, In : Journal of Sleep Research. 27, Supplement 1, 1 p., P007.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Preparation of multi-stimuli-responsive active colloids via RAFT polymerization-induced thermal self-assembly

Otsuka, I., Zhang, X. & Winnik, F., 19 Aug 2018, In : Abstracts of papers of the American Chemical Society . 256, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2017

Changes in risky alcohol use and sickness absence

Ervasti, J., Kivimäki, M., Pentti, J., Halonen, J. I., Vahtera, J. & Virtanen, M., Nov 2017, In : European Journal of Public Health. 27, suppl. 3, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Effect of Reference Panel in ID Score Regression Analysis of Lipid Traits in the Finnish Population

Hautakangas, H., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., 2017, In : Human Heredity. 83, 1, p. 10-10 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Turkki, R., Bychkov, D., Linder, N., Isola, J., Joensuu, H. T. & Lundin, J., 1 Jul 2017, In : Cancer Research. 77, 13 Supplement, p. 673 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Identifying ovarian cancer specific targeted drugs using high-throughput drug sensitivity profiles of primary cancer cells

Murumagi, A., Hirasawa, A., Khan, S., Ungureanu, D., Arjama, M., Pellinen, T., Eldfors, S., Koivisto-Korander, R., Leminen, A., Butzow, R., Aittokallio, T. & Kallioniemi, O., Jul 2017, In : Cancer Research. 77, Supplement 13, 2 p., 410.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Lipids, Neurotransmitters and their Receptors

Juhola, H., Lolicato, F., Postila, P., Vattulainen, I. & Rog, T., 3 Feb 2017, In : Biophysical Journal. 112, 3, Supplement 1, p. 392A-392A 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Molecular Basis of GLUT4 in Glucose Transport: Atomistic Molecular Dynamics Study

Poojari, C. S., Roodhuizen, J., Lolicato, F., Rog, T. & Vattulainen, I., 3 Feb 2017, In : Biophysical Journal. 112, 3, Supplement 1, p. 139A-139A 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Nanoparticle builder: new software for preparing nanoparticles for molecular dynamics simulations

Lolicato, F., Akola, J., Martinez-Searaa, H. & Vattulainen, I., Jul 2017, In : European Biophysics Journal. 46, 1 Supplement, p. S222-S222 1 p.

Research output: Contribution to journalMeeting AbstractResearch

NATURAL HISTORY OF CERVICAL INTRAEPITHELIAL NEOPLASIA GRADE 2 UNDER ACTIVE SURVEILLANCE - A SYSTEMATIC REVIEW AND META-ANALYSIS

Tainio, K., Athanasiou, A., Tikkinen, K., Aaltonen, R., Cardenas Hernandes, L., Glazer-Livson, S., Jakobsson, M., Joronen, K., Kiviharju, M., Louvanto, K., Oksjoki, S., Tahtinen, R., Virtanen, S., Nieminen, P., Kyrgiou, M. & Kalliala, I., Nov 2017, In : International Journal of Gynecological Cancer. 27, p. 25-25 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Oxidation of Cholesterol Changes the Permeability of Lipid Membranes

Kulig, W. T., Mikkolainen, H., Olzynska, A., Jurkiewicz, P., Cwiklik, L., Rog, T., Hof, M., Vattulainen, I. & Jungwirth, P., 3 Feb 2017, In : Biophysical Journal. 112, 3, p. 377A-377A 1 p.

Research output: Contribution to journalMeeting AbstractResearch

PI(4,5)P2 binds to phospholipase C delta 1 in a cholesterol concentration dependent manner: Perspective on implications to PI(4,5)P2 binding proteins

Rissanen, S., Salmela, L., Vattulainen, I. T. & Rog, T. J., 2017, In : Biophysical Journal. 112, 3, p. 137a-138a 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Redox-driven proton pumping in respiratory complex I: a molecular dynamics simulation study

Haapanen, O. & Sharma, V., Jul 2017, In : European Biophysics Journal. 46, Supplement 1, p. S216-S216 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Searching for Genetic Variants Matching a Given Multivariate Target Profile

Topa, H., Havulinna, A. S., Salomaa, V., Kähönen, M., Lehtimaki, T., Raitakari, O. T., Järvelin, M-R., Ala-Korpela, M., Wurtz, P. & Pirinen, M., 2017, In : Human Heredity. 83, 1, p. 25-26 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The Effect of Membrane Polyunsaturated Fatty Acids on Receptor Partitioning to Ordered Domains

Javanainen, M., Enkavi, G., Guixa-Gonzalez, R., Kulig, W., Martinez-Seara, H. & Vattulainen, I., 3 Feb 2017, In : Biophysical Journal. 112, 3, Suppl. 1, p. 230A-231A 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Transition from Direct to Inverse Cascade in Three-Dimensional Turbulence

Sahoo, G., Alexakis, A. & Biferale, L., 2017, In : Bulletin of the American Physical Society. 62, 14

Research output: Contribution to journalMeeting AbstractResearch

Open Access

Y NATURAL HISTORY OF CERVICAL INTRAEPITHELIAL NEOPLASIA GRADE 2 UNDER ACTIVE SURVEILLANCE - A SYSTEMATIC REVIEW AND META-ANALYSIS

Tainio, K., Athanasiou, A., Tikkinen, K., Aaltonen, R., Cardenas Hernandes, L., Glazer-Livson, S., Jakobsson, M., Joronen, K., Kiviharju, M., Louvanto, K., Oksjoki, S., Tahtinen, R., Virtanen, S., Nieminen, P., Kyrgiou, M. & Kalliala, I., Nov 2017, In : International Journal of Gynecological Cancer. 27, p. 893-893 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2016

Controls on neptunium behaviour in the environment

Law, G., Shaw, S., Lloyd, J., Livens, F., Pattrick, R., Bots, P., Rizoulis, A., Brookshaw, D., Thorpe, C., Williamson, A., Master-Waage, N., Mosselmans, F. & Morris, K., 13 Mar 2016, In : Abstracts of papers of the American Chemical Society . 251, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low Expression and Somatic Mutations of the KLHL6 Gene Predict Poor Survival in Patients with Activated B-Cell like Diffuse Large B-Cell Lymphoma

Meriranta, L., Pasanen, A., Cervera, A., Holte, H., Lehtonen, R., Hautaniemi, S. & Leppa, S., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low Expression of the CIITA Gene Predicts Poor Outcome in Diffuse Large B-Cell Lymphoma

Autio, M., Jantti, K., Cervera, A., Hautaniemi, S. & Leppa, S., 2 Dec 2016, In : Blood. 128, 22, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Mutational Landscape of Aggressive Natural Killer Cell Leukemia and Drug Sensitivity Profiling Reveal Therapeutic Options in Natural Killer Cell Malignancies

Dufva, O., Kankainen, M., Kelkka, T., Awad, S. A., Sekiguchi, N., Yadav, B., Eldfors, S., Kuusanmaki, H., Andersson, E. I., Malani, D., Pietarinen, P., Saikko, L., Kovanen, P. E., Suzumiya, J., Suzuki, R., Ko, Y. H., Kim, W. S., Chuang, S-S., Loughran, T. P., Chan, W. C. & 4 others, Ohshima, K., Aittokallio, T., Ishida, F. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 4 p., 2921.

Research output: Contribution to journalMeeting AbstractResearch

Novel therapeutic possibilities for chemorefractory ovarian cancer patients identified by functional ex vivo drug sensitivity testing of primary cells

Murumagi, A., Hirasawa, A., Khan, S., Arjama, M., Pellinen, T., Koivisto-Korander, R., Leminen, A., Magi, A., Aittokallio, T., Butzow, R. & Kallioniemi, O., Oct 2016, In : International Journal of Gynecological Cancer. 26, p. 653-653 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Proton Therapy Treatment Planning With MRI Only: Dose Calculation Accuracy in MRI-Derived Substitute Computed Tomography Images for Brain Tumor and Prostate Cancer Treatments

Koivula, L., Wee, L. & Korhonen, J., 1 Oct 2016, In : International Journal of Radiation: Oncology - Biology - Physics. 96, 2, Supplement 1, p. E623-E623 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Self-consistent evolution models for slow CMEs up to 1 AU

Poedts, S., Pomoell, J. & Zuccarello, F., 2016, In : AIP Conference Proceedings. 1714, 1, 030002.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

UNSTABLE LDL - NOVEL MECHANISM OF ATHEROGENESIS AND LINK TO CARDIOVASCULAR DEATHS

Ruuth, M., Nguyen, S. D., Vihervaara, T., Laajala, T. D., Uusitupa, M., Schwab, U., Savolainen, M., Sinisalo, J., Aittokallio, T., Kakela, R., Jauhiainen, M., Kovanen, P. & Oorni, K., Sep 2016, In : Atherosclerosis. 252, p. E208-E208 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Identification of Novel Candidate Genes in Canine Noise Phobia - A Model for Human Phobias

Hakosalo, O., Tiira, K., Sarviaho, R., Sillanpaa, M., Kere, J. & Lohi, H., 1 May 2015, In : Biological Psychiatry. 77, 9, p. 80S-81S 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2014

Acinetobacter in the skin microbiota protects from atopic sensitisation

Fyhrquist, N. T., Ruokolainen, L., Suomalainen, A., Lehtimaki, S., Veckman, V., Vendelin, J., Karisola, P., Savinko, T., Lehto, M., Jarva, H., Kosunen, T., Corander, J., Petri, A., von Hertzen, L., Laatikainen, T., Mäkelä, M., Haahtela, T., Greco, D., Hanski & Alenius, H., Sep 2014, In : Allergy : European journal of allergy and clinical immunology. 69, p. 4-5 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Characterization of the Microrna Expression Profiles of Paired Primary and Relapsed Diffuse Large B-Cell Lymphoma (DLBCL) By Next-Generation Sequencing

Leivonen, S-K., Icay, K., Liu, C., Taskinen, M., Lehtonen, R., Karjalainen-Lindsberg, M-L., Delabie, J., Holte, H., Hautaniemi, S. & Leppa, S., 6 Dec 2014, In : Blood. 124, 21, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Hunting new anxiety genes with the help of man's best friend, the dog

Hakosalo, O., Tiira, K., James, F., Jokinen, T., Sarviaho, R., Sillanpaa, M., Kere, J. & Lohi, H., 2014, In : International Journal of Molecular Medicine. 34, p. S88-S88 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Molecular-scale studies of radionuclide incorporation into mineral phases

Shaw, S., Marshall, T. A., Morris, K., Fuller, A. J., Law, G. T. W., Burke, I. T. & Mosselmans, F. W., 10 Aug 2014, In : Abstracts of papers of the American Chemical Society . 248, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Somatic Mutations in E3 Ubiquitin Ligase Deltex 1 Are Associated with Survival in Diffuse Large B-Cell Lymphoma

Taskinen, M., Meriranta, L., Pasanen, A., Louhimo, R., Cervera, A., Karjalainen-Lindsberg, M-L., Holte, H., Delabie, J., Lehtonen, R., Hautaniemi, S. & Leppa, S., 6 Dec 2014, In : Blood. 124, 21, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

The Effective Radiation Dose in the Diagnosis of Vesicouretal Reflux Using Two Different Techniques: Nuclear Medicine & Fluoroscopy

Pitkonen, M., Uusi-Simola, J., Hippelainen, E., Seuri, R., Kaijaluoto, S., Sipila, O. & Savolainen, S., Oct 2014, In : European Journal of Nuclear Medicine and Molecular Imaging. 41, p. S553-S554 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2013

Demographics, disease activity, and medication at baseline among patients with rheumatoid arthritis in Finland: an analysis of secular trends

Aaltonen, K., Joensuu, J., Virkki, L., Valleala, H., Relas, H., Romu, M., Uusitalo, T., Vuotila, J., Ilva, K., Parmanne, P., Peltoniemi, S., Kortelainen, S., Salonen, J. & Nordstrom, D., 2013, In : Scandinavian Journal of Rheumatology. 42, 5, p. 425-426 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Genetic Prediction of Type 2 Diabetes: A Meta-Analysis of Prospective Studies of 62,264 Individuals

Engage European Network Genetic, Jul 2013, In : Diabetes. 62, p. A32-A32 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Global Profiling Of Outcome Associated Alternative Splicing Events and Gene Expression In Diffuse Large B-Cell Lymphoma

Taskinen, M., Chen, P., Karjalainen-Lindsberg, M-L., Cervera, A., Delabie, J., Holte, H., Hautaniemi, S. & Leppae, S., 15 Nov 2013, In : Blood. 122, 21, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review