Projects per year
Organization profile
The group has biomedical and ecophysiological projects. The roles of lipids and fatty acids are studied in human vital functions and pathophysiology as well as in environmental adaptation and feeding ecology of animals. In addition to basic research we carry out applied projects. For example, together with our collaborators we develop functionality markers for stem cells used for transplantations, and improve methods for monitoring the diets of wide-ranging aquatic animals, such as seals and seabirds. The main methods used are mass spectrometry, chromatographic techniques and multivariate statistical analyses. The research group is a part of the lipidomics core facility of the university Helsinki University Lipidomics Unit offering analytical services to research groups, authorities and companies.
Fields of Science
- 1184 Genetics, developmental biology, physiology
- 1182 Biochemistry, cell and molecular biology
- 1181 Ecology, evolutionary biology
International and National Collaboration
Profiles
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Minna Holopainen
- Molecular and Integrative Biosciences Research Programme - Postdoctoral Researcher
- Functional Lipidomics Group
Person: U2 Teaching and research staff, UH
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Reijo Käkelä
- Molecular and Integrative Biosciences Research Programme - Senior University Lecturer
- Functional Lipidomics Group
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH
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Hanna Ruhanen
- Molecular and Integrative Biosciences Research Programme - Postdoctoral Researcher
- Functional Lipidomics Group
Person: U2 Teaching and research staff, UH
Equipment
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Helsinki University Lipidomics Unit
Reijo Käkelä (Manager), Hanna Elina Ruhanen (Operator), Minna Holopainen (Operator) & Pentti Juhani Somerharju (Manager)
Functional Lipidomics GroupFacility/equipment: Equipment
Projects
- 1 Finished
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Membrec (Membranes and Receptors)
Keinänen, K., Finne, J., Siljander, P., Gahmberg, C. G., Käkelä, R., Eskelinen, E. & Kukkonen, J.
01/01/2013 → 31/12/2016
Project: Research project
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Equine osteoarthritis modifies fatty acid signatures in synovial fluid and its extracellular vesicles
Mustonen, A-M., Lehmonen, N., Paakkonen, T., Raekallio, M., Kakela, R., Niemelä, T., Mykkaenen, A., Sihvo, S. P. & Nieminen, P., 9 Mar 2023, In: Arthritis research & therapy. 25, 1, 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Fatty Acid Fingerprints and Hyaluronic Acid in Extracellular Vesicles from Proliferating Human Fibroblast-like Synoviocytes
Mustonen, A-M., Paakkonen, T., Matilainen, J., Rilla, K., Käkelä, R., Malinen, M., Takabe, P., Oikari, S., Capra, J., Sihvo, S. P., Ryokas, P. & Nieminen, P., May 2022, In: International Journal of Molecular Sciences. 23, 10, 19 p., 5613.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Global effects of pharmacologic inhibition of OSBP in human umbilical vein endothelial cells
Taskinen, J. H., Ruhanen, H., Matysik, S., Käkelä, R. & Olkkonen, V. M., Sep 2022, In: Steroids. 185, 14 p., 109053.Research output: Contribution to journal › Article › Scientific › peer-review
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High Lipid Content of Prey Fish and n-3 PUFA Peroxidation Impair the Thiamine Status of Feeding-Migrating Atlantic Salmon (Salmo salar) and Is Reflected in Hepatic Biochemical Indices
Keinänen, M., Nikonen, S., Käkelä, R., Ritvanen, T., Rokka, M., Myllylä, T., Pönni, J. & Vuorinen, P. J., Apr 2022, In: Biomolecules. 12, 4, 27 p., 526.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Metabolic determination of cell fate through selective inheritance of mitochondria
Döhla, J., Kuuluvainen, E., Gebert, N., Amaral, A., Englund, J. I., Gopalakrishnan, S., Konovalova, S., Nieminen, A. I., Salminen, E. S., Torregrosa Munumer, R., Ahlqvist, K., Yang, Y., Bui, H., Otonkoski, T., Käkelä, R., Hietakangas, V., Tyynismaa, H., Ori, A. & Katajisto, P., Feb 2022, In: Nature Cell Biology. 24, 2, p. 148-+ 27 p.Research output: Contribution to journal › Article › Scientific › peer-review
Activities
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Principles of bioscience omics, Lectures 10 cr, NEU-561
Vilja Pietiäinen (Teacher), Reijo Käkelä (Teacher) & Mari Palviainen (Teacher)
2022 → …Activity: Other activity types › Types for other activities - External teaching and subject coordination
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Environmental effects of fish introductions in small, high-latitude lakes
Marco Milardi (Speaker), Reijo Tapio Käkelä (Speaker), Jan Björn Weckström (Speaker) & Kimmo Kahilainen (Speaker)
2014Activity: Talk or presentation types › Oral presentation
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University of Oulu (External organisation)
Reijo Käkelä (Assessment)
5 May 2006 → 8 May 2006Activity: Membership types › Assessment of candidates for academic posts