Projects per year
Organisation profile
Organisation Profile
The group has biomedical and ecophysiological projects. The roles of lipids and fatty acids are studied in human vital functions and pathophysiology as well as in environmental adaptation and feeding ecology of animals. In addition to basic research we carry out applied projects. For example, together with our collaborators we develop functionality markers for stem cells used for transplantations, and improve methods for monitoring the diets of wide-ranging aquatic animals, such as seals and seabirds. The main methods used are mass spectrometry, chromatographic techniques and multivariate statistical analyses. The research group is a part of the lipidomics core facility of the university Helsinki University Lipidomics Unit offering analytical services to research groups, authorities and companies.
Fields of Science
- 1184 Genetics, developmental biology, physiology
- 1182 Biochemistry, cell and molecular biology
- 1181 Ecology, evolutionary biology
International and National Collaboration
Profiles
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Reijo Käkelä
- Molecular and Integrative Biosciences Research Programme - Senior University Lecturer
- Functional Lipidomics Group
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH
Equipment
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Helsinki University Lipidomics Unit (LS-RIA/ Metabo-HiLIFE)
Käkelä, R. (Manager), Ruhanen, H. E. (Operator), Holopainen, M. (Operator) & Somerharju, P. J. (Manager)
Functional Lipidomics GroupFacility/equipment: Core Facility
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Browning lakes in the greening Arctic
Weckström, J. (Project manager), Heikkilä, M. (Participant), Heikkilä, M. (Participant), Keva, O. (Participant), Koski, K. J. A. (Participant), Käkelä, R. (Participant), McGowan, S. (Participant), Meyer-Jacob, C. (Participant), Orozco, L. (Participant), Smol, J. (Participant), Strötz, L. M. (Participant), Virtanen, T. (Participant), Weckström, K. (Participant) & Weckström, K. (Participant)
01/09/2023 → 31/08/2027
Project: Research Council of Finland: Academy Project
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Membrec (Membranes and Receptors)
Keinänen, K. (Participant), Finne, J. (Participant), Siljander, P. (Participant), Gahmberg, C. G. (Participant), Käkelä, R. (Participant), Eskelinen, E.-L. (Participant) & Kukkonen, J. (Participant)
01/01/2013 → 31/12/2016
Project: Research project
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ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism
Löf, C., Sultana, N., Goel, N., Heron, S., Wahlström, G., House, A., Holopainen, M., Käkelä, R. & Schleutker, J., 8 Feb 2025, In: Cell Communication and Signaling. 23, 1, 19 p., 71.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Improvement of high-density lipoprotein atheroprotective properties in patients with systemic lupus erythematosus after belimumab treatment
Dedemadi, A., Gkolfinopoulou, C., Nikoleri , D., Nikoloudaki, M., Ruhanen, H., Holopainen, M., Käkelä, R., Christopoulou, G., Bournazos, S., Constantoulakis, P., Sidiropoulos, P., Bertsias, G. & Chroni , A., Feb 2025, In: Rheumatology. 64, 2, p. 648-657 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Pain and functional limitations in knee osteoarthritis are reflected in the fatty acid composition of plasma extracellular vesicles
Mustonen, A.-M., Julkunen, P., Saisanen, L., Karttunen, L., Esrafilian, A., Reijonen, J., Tollis, S., Käkelä, R., Sihvo, S. P., Höglund, N., Niemelä, T., Mykkänen, A., Maki, J., Kröger, H., Arokoski, J. & Nieminen, P., Apr 2025, In: Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1870, 3, 12 p., 159602.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Seasonal and genetic effects on lipid profiles of juvenile Atlantic salmon
House, A. H., Debes, P. V., Holopainen, M., Käkelä, R., Donner, I., Frapin, M., Ahi, E. P., Kurko, J., Ruhanen, H. & Primmer, C. R., Jan 2025, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1870, 1, 10 p., 159565.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
The lipidome and proteome of high-density lipoprotein are altered in menopause.
Lehti, S., Korhonen, T.-M., Soliymani, R., Ruhanen, H., Lähteenmäki, E., Palviainen, M., Siljander, P., Lalowski, M., Käkelä, R., Lehti, M. & Laakkonen, E. K., 11 Jan 2025, (BioRxiv beta : the preprint server for biology).Research output: Working paper › Preprint
Open AccessFile
Activities
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Lipid species profiling of equine bronchoalveolar lavage cells: a comparison of lipid profiles of horses housed on two different bedding materials
Mönki, J. (Speaker)
14 Nov 2023Activity: Talk or presentation types › Invited talk
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Principles of bioscience omics, Lectures 10 cr, NEU-561
Pietiäinen, V. (Teacher), Käkelä, R. (Teacher) & Palviainen, M. (Teacher)
2022 → …Activity: Other activity types › Types for other activities - External teaching and subject coordination
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Environmental effects of fish introductions in small, high-latitude lakes
Milardi, M. (Speaker), Käkelä, R. T. (Speaker), Weckström, J. B. (Speaker) & Kahilainen, K. (Speaker)
2014Activity: Talk or presentation types › Oral presentation
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University of Oulu (External organisation)
Käkelä, R. (Assessment)
5 May 2006 → 8 May 2006Activity: Membership types › Assessment of candidates for academic posts