• P.O. Box 65 (Viikinkaari 1)

    00014 University of Helsinki

    Finland

Organization profile

Organisation Profile

The group has biomedical and ecophysiological projects. The roles of lipids and fatty acids are studied in human vital functions and pathophysiology as well as in environmental adaptation and feeding ecology of animals. In addition to basic research we carry out applied projects. For example, together with our collaborators we develop functionality markers for stem cells used for transplantations, and improve methods for monitoring the diets of wide-ranging aquatic animals, such as seals and seabirds. The main methods used are mass spectrometry, chromatographic techniques and multivariate statistical analyses. The research group is a part of the lipidomics core facility of the university Helsinki University Lipidomics Unit offering analytical services to research groups, authorities and companies.

International and National Collaboration Publications and projects within past five years.

Equipment

Projects

Publications

ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins

Ruhanen, H., Haridas, P. A. N., Minicocci, I., Taskinen, J. H., Palmas, F., di Costanzo, A., D'Erasmo, L., Metso, J., Partanen, J., Dalli, J., Zhou, Y., Arca, M., Jauhiainen, M., Käkelä, R. & Olkkonen, V. M., Jul 2020, In : Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1865, 7, 11 p., 158679.

Research output: Contribution to journalArticleScientificpeer-review

Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism

Matilainen, J., Mustonen, A-M., Rilla, K., Kakela, R., Sihvo, S. P. & Nieminen, P., 13 Apr 2020, In : Lipids in Health and Disease. 19, 1, 15 p., 70.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Anterior cruciate ligament transection alters the n-3/n-6 fatty acid balance in the lapine infrapatellar fat pad

Mustonen, A-M., Käkelä, R., Finnilä, M. A. J., Sawatsky, A., Korhonen, R. K., Saarakkala, S., Herzog, W., Paakkonen, T. & Nieminen, P., 18 Mar 2019, In : Lipids in Health and Disease. 18, 67, 9 p., 67.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

A transposable element insertion is associated with an alternative life history strategy

Woronik, A., Tunstrom, K., Perry, M. W., Neethiraj, R., Stefanescu, C., Celorio-Mancera, M. D. L. P., Brattstrom, O., Hill, J., Lehmann, P., Käkelä, R. & Wheat, C. W., 17 Dec 2019, In : Nature Communications. 10, 11 p., 5757.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Complementary methods assessing short and long-term prey of a marine top predator - Application to the grey seal-fishery conflict in the Baltic Sea

Tverin, M., Esparza-Salas, R., Strömberg, A., Tang, P., Kokkonen, I., Herrero, A., Kauhala, K., Karlsson, O., Tiilikainen, R., Vetemaa, M., Sinisalo, T., Käkelä, R. & Lundström, K., 2 Jan 2019, In : PLoS One. 14, 1, 26 p., 0208694.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Activities

  • 1 Assessment of candidates for academic posts
  • 1 Oral presentation

Environmental effects of fish introductions in small, high-latitude lakes

Marco Milardi (Speaker), Reijo Tapio Käkelä (Speaker), Jan Björn Weckström (Speaker), Kimmo Kahilainen (Speaker)
2014

Activity: Talk or presentation typesOral presentation

University of Oulu (External organisation)

Reijo Käkelä (Assessment)
5 May 20068 May 2006

Activity: Membership typesAssessment of candidates for academic posts