• P.O. Box 65 (Viikinkaari 1)

    00014 University of Helsinki

    Finland

Organization profile

Organisation Profile

The group has biomedical and ecophysiological projects. The roles of lipids and fatty acids are studied in human vital functions and pathophysiology as well as in environmental adaptation and feeding ecology of animals. In addition to basic research we carry out applied projects. For example, together with our collaborators we develop functionality markers for stem cells used for transplantations, and improve methods for monitoring the diets of wide-ranging aquatic animals, such as seals and seabirds. The main methods used are mass spectrometry, chromatographic techniques and multivariate statistical analyses. The research group is a part of the lipidomics core facility of the university Helsinki University Lipidomics Unit offering analytical services to research groups, authorities and companies.

International and National Collaboration Publications and projects within past five years.

Equipment

Publications 2005 2019

Anterior cruciate ligament transection alters the n-3/n-6 fatty acid balance in the lapine infrapatellar fat pad

Mustonen, A-M., Käkelä, R., Finnilä, M. A. J., Sawatsky, A., Korhonen, R. K., Saarakkala, S., Herzog, W., Paakkonen, T. & Nieminen, P., 18 Mar 2019, In : Lipids in Health and Disease. 18, 67, 9 p., 67.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Distinct fatty acid signatures in infrapatellar fat pad and synovial fluid of patients with osteoarthritis versus rheumatoid arthritis

Mustonen, A-M., Käkelä, R., Lehenkari, P., Huhtakangas, J., Turunen, S., Joukainen, A., Kaariainen, T., Paakkonen, T., Kroger, H. & Nieminen, P., 22 May 2019, In : Arthritis research & therapy. 21, 11 p., 124.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

A retrospective study of fatty acid composition in Baltic herring (Clupea harengus membras) caught at three locations in the Baltic Sea (1973-2009)

Lind, Y., Huovila, T. & Käkelä, R., 2018, In : ICES Journal of Marine Science. 75, 1, p. 330-339 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties

Lehti, S., Nguyen, S. D., Belevich, I., Vihinen, H., Heikkilä, H. M., Soliymani, R., Käkelä, R., Saksi, J., Jauhiainen, M., Grabowski, G. A., Kummu, O., Hörkkö, S., Baumann, M., Lindsberg, P. J., Jokitalo, E., Kovanen, P. T. & Öörni, K., Feb 2018, In : The American Journal of Pathology. 188, 2, p. 525-538 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Activities 2014 2014

  • 1 Oral presentation

Environmental effects of fish introductions in small, high-latitude lakes

Marco Milardi (Speaker), Reijo Tapio Käkelä (Speaker), Jan Björn Weckström (Speaker), Kimmo Kahilainen (Speaker)
2014

Activity: Talk or presentation typesOral presentation