Projects per year
Organisation profile
Organisation Profile
The Glycoscience group headed by Professor Jukka Finne is engaged with the biology of carbohydrates, the most abundant biological molecules of nature, involved in the biology of all living organisms. Glycans have received little attention due to lack of efficient tools to probe their complex structures and properties.
The group has focused on the study of two main topics of carbohydrate interactions: the role of polysialic acid, a developmentally regulated carbohydrate moiety of cell adhesion molecules originally discovered by us, in the childhood cancer neuroblastoma, as well as the role of cell surface carbohydrates in the adhesion of pathogenic bacteria to the cells of our body.
Fields of Science
- 1182 Biochemistry, cell and molecular biology
- 1183 Plant biology, microbiology, virology
- Microbiology
- 3111 Biomedicine
- 3112 Neurosciences
- 3122 Cancers
International and National Collaboration
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Role of polysialic acid in human neuroblastoma
Finne, J. (Project manager), Vettenranta, K. (Participant), Sariola, H. (Participant), Porkka, K. (Participant) & Lehti, T. (Participant)
Project: Research project
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Neural cell adhesion molecule and polysialic acid in clinical-grade human bone marrow-derived mesenchymal stromal cell
Skog, M. (Participant), Pajunen, M. (Participant), Anderson, H. (Participant) & Colley, K. (Participant)
Project: Research project
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Cytotoxic constructs targeting polysialic acid
Lehti, T. (Participant), Skog, M. (Participant), Lilie, H. (Participant), Nacher, J. (Participant) & Finne, J. (Project manager)
Project: Research project
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Neural cell adhesion molecule and polysialic acid in clinical-grade human bone marrow-derived mesenchymal stromal cell
Skog, M. (Participant), Pajunen, M. (Participant), Anderson, H. (Participant), Colley, K. (Participant) & Finne, J. (Project manager)
Project: Research project
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Regulation of polysialic acid expression
Pajunen, M. (Participant), Anderson, H. (Participant), Lehti, T. (Participant), Skog, M. (Participant), Schachner, M. (Participant), Kallioniemi, O. (Participant), Saarela, J. (Participant) & Finne, J. (Project manager)
Project: Research project
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Discovery of Bactericidal Proteins from Staphylococcus Phage Stab21 Using a High-Throughput Screening Method
Nyhamar, E., Webber, P., Liong, O., Yilmaz, O., Pajunen, M., Skurnik, M. & Wan, X., Jul 2023, In: Antibiotics. 12, 7, 15 p., 1213.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
The DNA polymerase of bacteriophage YerA41 replicates its T-modified DNA in a primer-independent manner
Gomez-Raya-Vilanova, M. V., Leskinen, K., Bhattacharjee, A., Virta, P., Rosenqvist, P., Smith, J. L. R., Bayfield, O. W., Homberger, C., Kerrinnes, T., Vogel, J., Pajunen, M. & Skurnik, M., 22 Apr 2022, In: Nucleic Acids Research. 50, 7, p. 3985-3997 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Bacteriophages fEV-1 and fD1 Infect Yersinia pestis
Skurnik, M., Jaakkola, S., Mattinen, L., von Ossowski, L., Nawaz, A., Pajunen, M. & Happonen, L. J., Jul 2021, In: Viruses (Basel). 13, 7, 21 p., 1384.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
BtuB-Dependent Infection of the T5-like Yersinia Phage phi R2-01
Happonen, L. J., Pajunen, M. I., Jun, J. W. & Skurnik, M., Nov 2021, In: Viruses (Basel). 13, 11, 18 p., 2171.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Design of a cytotoxic neuroblastoma-targeting agent using an enzyme acting on polysialic acid fused to a toxin
Lehti, T., Pajunen, M., Jokilammi, A., Korja, M. J., Lilie, H., Vettenranta, K. & Finne, J., Oct 2021, In: Molecular Cancer Therapeutics. 20, 10, p. 1996-2007 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Activities
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Glycoconjugate Journal (Journal)
Finne, J. (Reviewer)
2023Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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Member of the Scientific Advisory Board of Sialoglyco 2020 Meeting, Gifu, Japan
Finne, J. (Scientific Committee Member)
2020Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Member of the Council of the Finnish Union of University Professors
Finne, J. (Participant)
2019 → 2020Activity: Other activity types › Types for other activities - Other
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Invited speaker at 25th International Symposium on Glycoconjugates, Milan, Italy
Finne, J. (Speaker: Presenter)
2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Societas Biophysica, Biochimica et Microbiologica Fenniae (External organisation)
Finne, J. (Board member)
2019Activity: Membership types › Membership or other role in national/international committee, council, board
Prizes
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Awarded as a member of the MembRec group in the International evaluation of research and doctoral training training of the University of Helsinki
Finne, J. (Recipient), 2013
Prize: Prizes and awards
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Golden medal of the Federation of Finnish Learned Societies and Universities Finland UNIFI
Finne, J. (Recipient), 2016
Prize: Prizes and awards
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Young Researcher's Prize of Duodecim (Finnish College of Physicians)
Finne, J. (Recipient), 1985
Prize: Prizes and awards
Press/Media
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Interviewed for an article in Yliopisto-lehti
01/01/2015
1 Media contribution
Press/Media: Press / Media
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Interviewed for an article in Teknia Journal
01/01/1995
1 Media contribution
Press/Media: Press / Media
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