Publications

2020

Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent

Serfozo, P., Wysocki, J., Gulua, G., Schulze, A., Ye, M., Liu, P., Jin, J., Bader, M., Myöhänen, T., Garcia Horsman, J. A. & Batlle, D., Jan 2020, In : Hypertension. 75, 1, p. 173-182 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Anterior insula stimulation suppresses appetitive behavior while inducing forebrain activation in alcohol-preferring rats

Haaranen, M., Scuppa, G., Tambalo, S., Järvi, V., Bertozzi, S. M., Armirotti, A., Sommer, W. H., Bifone, A. & Hyytiä, P., 18 May 2020, In : Translational Psychiatry. 10, 1, 11 p., 150.

Research output: Contribution to journalArticleScientificpeer-review

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Cerebral Dopamine Neurotrophic Factor Regulates Multiple Neuronal Subtypes and Behavior

Chen, Y-C., Baronio, D., Semenova, S., Abdurakhmanova, S. & Panula, P., 5 Aug 2020, In : Journal of Neuroscience. 40, 32, p. 6146-6164 19 p.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of ANGPT2 mutations associated with primary lymphedema

Leppänen, V-M., Brouillard, P., Korhonen, E. A., Sipilä, T., Jha, S. K., Revencu, N., Labarque, V., Fastré, E., Schlögel, M., Ravoet, M., Singer, A., Luzzatto, C., Angelone, D., Crichiutti, G., D’Elia, A., Kuurne, J., Elamaa, H., Koh, G. Y., Saharinen, P., Vikkula, M. & 1 others, Alitalo, K., 9 Sep 2020, In : Science translational medicine. 12, 560

Research output: Contribution to journalArticleScientificpeer-review

Comparison of clinically relevant oncolytic virus platforms for enhancing T-cell therapy of solid tumors

Cervera-Carrascon, V., Quixabeira, D. C. A., Havunen, R., Santos, J. M., Kutvonen, E., Clubb, J. H. A., Siurala, M., Heiniö, C., Zafar, S., Koivula, T., Lumen, D., Vaha, M., Garcia-Horsman, A., Airaksinen, A. J., Sorsa, S., Anttila, M., Hukkanen, V., Kanerva, A. & Hemminki, A., 26 Jun 2020, In : Molecular Therapy - Oncolytics. 17, p. 47-60 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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Control of vascular integrity via endothelial growth factor and integrin cell adhesion receptor pathways

Hakanpää, L., 2020, Helsinki: Helsingin yliopisto. 89 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Evaluation of Organo [F-18]Fluorosilicon Tetrazine as a Prosthetic Group for the Synthesis of PET Radiotracers

Otaru, S., Imlimthan, S., Sarparanta, M., Helariutta, K., Wähälä, K. & Airaksinen, A., 1 Mar 2020, In : Molecules. 25, 5, 17 p., 1208.

Research output: Contribution to journalArticleScientificpeer-review

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Finnish neuroscience from past to present

Korpi, E. R., Lindholm, D., Panula, P., Tienari, P. J. & Haltia, M., 3 Feb 2020, In : European Journal of Neuroscience. 17 p.

Research output: Contribution to journalEditorialScientific

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Genetic lack of histamine upregulates dopamine neurotransmission and alters rotational behavior but not levodopa-induced dyskinesia in a mouse model of Parkinson’s disease

Koski, S. K., Leino, S., Panula, P., Rannanpää, S. & Salminen, O., 11 Jun 2020, In : Neuroscience Letters. 729, 6 p., 134932.

Research output: Contribution to journalArticleScientificpeer-review

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Hevosten nivelten juveniilit osteokondraaliset sairaudet – Kirjallisuuskatsaus

Translated title of the contribution: Juvenile osteochondral diseases in equine joints – ReviewMuilu, L. & Ruohoniemi, M., 2020, In : Eläinlääkäri : Suomen eläinlääkärilehti. 126, 2, p. 75-80 6 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Histamine, histamine H3 receptor, and alcohol use disorder

Panula, P., 22 Feb 2020, In : British Journal of Pharmacology. 177, 3, p. 634-641 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

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Increased Sensitivity of Mice Lacking Extrasynaptic delta-Containing GABA(A) Receptors to Histamine Receptor 3 Antagonists

Abdurakhmanova, S., Grotell, M., Kauhanen, J., Linden, A-M., Korpi, E. R. & Panula, P., 6 May 2020, In : Frontiers in Pharmacology. 11, 13 p., 594.

Research output: Contribution to journalArticleScientificpeer-review

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KCC2 regulates dendritic spine development

Llano Sanchez, O., Rivera Baeza, C. & Ludwig, A., 19 Jun 2020, Neuronal Chloride Transporters in Health and Disease. Tang, X. (ed.). 1 ed. Elsevier Academic Press

Research output: Chapter in Book/Report/Conference proceedingChapterScientific

Preparation and In vivo Evaluation of Red Blood Cell Membrane Coated Porous Silicon Nanoparticles Implanted with 155Tb

Jakobsson, U., Mäkilä, E., Rahikkala, A. T. A., Imlimthan, S., Lampuoti, J., Ranjan, S., Heino, J., Jalkanen, P., Köster, U., Mizohata, K., Santos, H. A., Salonen, J., Airaksinen, A., Sarparanta, M. & Helariutta, K., May 2020, In : Nuclear Medicine and Biology. 84-85, p. 102-110 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Rotation and torsion of the left ventricle with cardiovascular magnetic resonance tagging: comparison of two analysis methods

Lehmonen, L., Jalanko, M., Tarkiainen, M., Kaasalainen, T., Kuusisto, J., Lauerma, K-M. S. & Savolainen, S., 1 Jul 2020, In : BMC Medical Imaging. 20, 1, 8 p., 73.

Research output: Contribution to journalArticleScientificpeer-review

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Sparse dynamic tomography: a shearlet-based approach for iodine perfusion in plant stems

Bubba, T., Heikkilä, T., Help, H., Huotari, S., Salmon, Y. & Siltanen, S., 1 Sep 2020, In : Inverse Problems. 36, 9, 34 p., 094002.

Research output: Contribution to journalArticleScientificpeer-review

2019

3D Convolutional Neural Network Applied to CT Angiography in the Detection of an Acute Ischemic Stroke

Öman, O., Mäkelä, T., Salli, E., Savolainen, S. & Kangasniemi, M., 2019, In : European radiology experimental. 3, 11 p., 8.

Research output: Contribution to journalArticleScientificpeer-review

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Abnormal behavior, striatal dopamine turnover and opioid peptide gene expression in histamine-deficient mice

Abdurakhmanova, S., Semenova, S., Piepponen, T. P. & Panula, P., Nov 2019, In : Genes, Brain and Behavior. 18, 8, 12 p., 12595.

Research output: Contribution to journalArticleScientificpeer-review

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Brain-Derived Neurotrophic Factor and Vascular Endothelial Growth Factor: "Siamese Twins" in Antidepressant Action

Lima-Ojeda, J. M. & Castren, E., 15 Jul 2019, In : Biological Psychiatry. 86, 2, p. 81-83 3 p.

Research output: Contribution to journalArticleScientific

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Bumetanide Prevents Brain Trauma-Induced Depressive-Like Behavior

Goubert, E., Altvater, M., Rovira, M-N., Khalilov, I., Mazzarino, M., Sebastiani, A., Schaefer, M. K. E., Rivera, C. & Pellegrino, C., 5 Feb 2019, In : Frontiers in Molecular Neuroscience. 12, 18 p., 12.

Research output: Contribution to journalArticleScientificpeer-review

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Defect-Driven Enhancement of Electrochemical Oxygen Evolution on Fe-Co-Al Ternary Hydroxides

Sun, Y., Xia, Y., Kuai, L., Sun, H., Cao, W., Huttula, M., Honkanen, A-P., Viljanen, M., Huotari, S. & Geng, B., 21 Jun 2019, In : ChemSusChem. 12, 12, p. 2564-2569 6 p.

Research output: Contribution to journalArticleScientificpeer-review

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High-Energy X-Ray Compton Scattering Imaging of 18650-Type Lithium-Ion Battery Cell

Suzuki, K., Honkanen, A-P., Tsuji, N., Jalkanen, K., Koskinen, J., Morimoto, H., Hiramoto, D., Terasaka, A., Hafiz, H., Sakurai, Y., Kanninen, M., Huotari, S., Bansil, A., Sakurai, H. & Barbiellini, B., Sep 2019, In : Condensed matter. 4, 3, 8 p., 66.

Research output: Contribution to journalArticleScientificpeer-review

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History, clinical findings and outcome of horses with radiographical signs of equine odontoclastic tooth resorption and hypercementosis

Rahmani, V., Häyrinen, L., Kareinen, I. & Ruohoniemi, M., 14 Dec 2019, In : Veterinary Record. 185, 23, 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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Intercalation of Lithium Ions from Gaseous Precursors into beta-MnO2 Thin Films Deposited by Atomic Layer Deposition

Nieminen, H., Miikkulainen, V., Settipani, D., Simonelli, L., Hönicke, P., Zech, C., Kayser, Y., Beckhoff, B., Honkanen, A-P., Heikkilä, M., Mizohata, K., Meinander, N. K., Ylivaara, O. M. E., Huotari, S. & Ritala, M., 27 Jun 2019, In : Journal of Physical Chemistry C. 123, 25, p. 15802-15814 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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In vivo Two-Photon Imaging of Anesthesia-Specific Alterations in Microglial Surveillance and Photodamage-Directed Motility in Mouse Cortex

Sun, W., Suzuki, K., Toptunov, D., Stoyanov, S., Yuzaki, M., Khiroug, L. & Dilyatev, A., 7 May 2019, In : Frontiers in Neuroscience. 13, 12 p., 421.

Research output: Contribution to journalArticleScientificpeer-review

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Neurotrophin receptor Ntrk2b function in the maintenance of dopamine and serotonin neurons in zebrafish

Sahu, M. P., Pazos-Boubeta, Y., Pajanoja, C., Rozov, S., Panula, P. & Castren, E., 14 Feb 2019, In : Scientific Reports. 9, 13 p., 2036.

Research output: Contribution to journalArticleScientificpeer-review

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New enzymes of dopamine metabolism in the zebrafish Danio rerio

Semenova, S., 2019, Helsinki: [S. Semenova]. 89 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Owner-Reported Clinical Signs and Management-Related Factors in Horses Radiographed for Intestinal Sand Accumulation

Niinistö, K. E., Määttä, M. A., Ruohoniemi, M. O., Paulaniemi, M. & Raekallio, M. R., Sep 2019, In : Journal of Equine Veterinary Science. 80, p. 10-15 6 p.

Research output: Contribution to journalArticleScientificpeer-review

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Porous Silicon as a Platform for Radiation Theranostics Together with a Novel RIB-Based Radiolanthanoid

Jakobsson, U., Mäkilä, E., Airaksinen, A. J., Alanen, O., Etile, A., Köster, U., Ranjan, S., Salonen, J., Santos, H. A. & Helariutta, K., 12 Mar 2019, In : Contrast Media & Molecular Imaging. 2019, 9 p., 3728563.

Research output: Contribution to journalArticleScientificpeer-review

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Potential occupational exposures in diagnostic and interventional radiology: statistical modeling based on Finnish national dose registry data

Pekkarinen, A., Siiskonen, T., Lehtinen, M., Savolainen, S. & Kortesniemi, M., Jan 2019, In : Acta Radiologica. 60, 1, p. 68-77 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Radiolabeled Molecular Imaging Probes for the in Vivo Evaluation of Cellulose Nanocrystals for Biomedical Applications

Imlimthan, S., Otaru, S., Keinänen, O., Correia, A., Lintinen, K., Almeida Santos, H., Airaksinen, A., Kostiainen, M. & Sarparanta, M., Feb 2019, In : Biomacromolecules. 20, 2, p. 674–683 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify Kras Mutant Lung Cancers

Talwelkar, S. S., Nagaraj, A. S., Devlin, J. R., Hemmes, A., Potdar, S., Kiss, E. A., Saharinen, P., Salmenkivi, K. M., Mäyränpää, M. I., Wennerberg, K. & Verschuren, E., Oct 2019, In : Molecular Cancer Therapeutics. 18, 10, p. 1863-1874 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Regeneration of Dopaminergic Neurons in Adult Zebrafish Depends on Immune System Activation and Differs for Distinct Populations

Caldwell, L. J., Davies, N. O., Cavone, L., Mysiak, K. S., Semenova, S. A., Panula, P., Armstrong, J. D., Becker, C. G. & Becker, T., 12 Jun 2019, In : Journal of Neuroscience. 39, 24, p. 4694-4713 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Site-Specific In-111-Radiolabeling of Dual-PEGylated Porous Silicon Nanoparticles and Their In Vivo Evaluation in Murine 4T1 Breast Cancer Model

Lumen, D., Näkki, S., Imlimthan, S., Lambidis, E., Sarparanta, M., Xu, W., Lehto, V-P. & Airaksinen, A. J., Dec 2019, In : Pharmaceutics. 11, 12, 16 p., 686.

Research output: Contribution to journalArticleScientificpeer-review

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The bradykinin system in stress and anxiety in humans and mice

Rouhiainen, A., Kulesskaya, N., Mennesson, M., Misiewicz, Z., Sipila, T., Sokolowska, E., Trontti, K., Urpa, L., McEntegart, W., Saarnio, S., Hyytia, P. & Hovatta, I., 19 Dec 2019, In : Scientific Reports. 9, 13 p., 19437.

Research output: Contribution to journalArticleScientificpeer-review

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The Radiopharmaceutical Chemistry of Fluorine-18: Next-Generation Fluorinations

Airaksinen, A., 2019, Radiopharmaceutical Chemistry. Lewis, J. S., Windhorst, A. D. & Zeglis, B. M. (eds.). Cham: Springer International Publishing AG, p. 297-310 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientific

The value of academics' formal and informal interaction in developing life science education

Katajavuori, N., Virtanen, V., Ruohoniemi, M., Muukkonen, H. & Toom, A., 7 Jun 2019, In : Higher Education Research and Development. 38, 4, p. 793-806 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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Transient modification of lin28b expression - Permanent effects on zebrafish growth

Leinonen, J. T., Chen, Y-C., Tukiainen, T., Panula, P. & Widen, E., 5 Jan 2019, In : Molecular and Cellular Endocrinology. 479, p. 61-70 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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2018

Abscopal Effect in Non-injected Tumors Achieved with Cytokine-Armed Oncolytic Adenovirus

Havunen, R., Santos, J. M., Sorsa, S., Rantapero, T., Lumen, D., Siurala, M., Airaksinen, A. J., Cervera-Carrascon, V., Tähtinen, S., Kanerva, A. & Hemminki, A., 21 Dec 2018, In : Molecular Therapy - Oncolytics. 11, p. 109-121 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Addiktion neurobiologia

Hyytiä, P., 2018, In : Duodecim. 134, 20, p. 2031-2038 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

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A high-energy-resolution resonant inelastic X-ray scattering spectrometer at ID20 of the European Synchrotron Radiation Facility

Sala, M. M., Martel, K., Henriquet, C., Al Zein, A., Simonelli, L., Sahle, C. J., Gonzalez, H., Lagier, M-C., Ponchut, C., Huotari, S., Verbeni, R., Krisch, M. & Monaco, G., Mar 2018, In : Journal of Synchrotron Radiation. 25, p. 580-591 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Automated analysis of images for molecular quantification in immunohistochemistry

Guirado, R., Carceller, H., Castillo-Gomez, E., Castren, E. & Nacher, J., Jun 2018, In : Heliyon. 4, 6, 16 p., 00669.

Research output: Contribution to journalArticleScientificpeer-review

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Delivery of Agents Into Articular Cartilage With Electric Spark-Induced Sound Waves

Pérez, A. G., Nieminen, H. J., Finnilä, M., Salmi, A., Pritzker, K. P. H., Lampsijärvi, E., Paulin, T., Airaksinen, A. J., Saarakkala, S. & Haeggström, E., 16 Oct 2018, In : Frontiers in Physics. 6, 7 p., 116.

Research output: Contribution to journalArticleScientificpeer-review

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