Publications 2016 2019

Filter
Article
2019
Open Access
File

8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia

Buettner, R., Le Xuan Truong Nguyen, Kumar, B., Morales, C., Liu, C., Chen, L. S., Pemovska, T., Synold, T. W., Palmer, J., Thompson, R., Li, L., Dinh Hoa Hoang, Zhang, B., Ghoda, L., Kowolik, C., Kontro, M., Leitch, C., Wennerberg, K., Yu, X., Chen, C-C. & 5 othersHorne, D., Gandhi, V., Pullarkat, V., Marcucci, G. & Rosen, S. T., Sep 2019, In : Journal of Cellular Physiology. 234, 9, p. 16295-16303 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Acute GVHD prophylaxis plus ATLG after myeloablative allogeneic haemopoietic peripheral blood stem-cell transplantation from HLA-identical siblings in patients with acute myeloid leukaemia in remission: final results of quality of life and long-term outcome analysis of a phase 3 randomised study

Bonifazi, F., Solano, C., Wolschke, C., Sessa, M., Patriarca, F., Zallio, F., Nagler, A., Selleri, C., Risitano, A. M., Messina, G., Bethge, W., Herrera, P., Sureda, A., Carella, A. M., Cimminiello, M., Guidi, S., Finke, J., Sorasio, R., Ferra, C., Sierra, J. & 13 othersRusso, D., Benedetti, E., Milone, G., Benedetti, F., Heinzelmann, M., Pastore, D., Jurado, M., Terruzzi, E., Narni, F., Voelp, A., Ayuk, F., Ruutu, T. & Kroeger, N., Feb 2019, In : The lancet. Haematology. 6, 2, p. E89-E99 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Anagrelide for Gastrointestinal Stromal Tumor

Pulkka, O-P., Gebreyohannes, Y. K., Wozniak, A., Mpindi, J-P., Tynninen, O., Icay, K., Cervera, A., Keskitalo, S., Murumägi, A., Kulesskiy, E., Laaksonen, M., Wennerberg, K., Varjosalo, M., Laakkonen, P., Lehtonen, R., Hautaniemi, S., Kallioniemi, O., Schöffski, P., Sihto, H. & Joensuu, H., 1 Mar 2019, In : Clinical Cancer Research. 25, 5, p. 1676-1687 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Antibody response to the 23-valent pneumococcal polysaccharide vaccine after conjugate vaccine in patients with chronic lymphocytic leukemia

Lindström, V., Aittoniemi, J., Salmenniemi, U., Käyhty, H., Huhtala, H. & Sinisalo, M., 29 Jun 2019, In : Human Vaccines & Immunotherapeutics. 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Antikoagulaatiohoidon seuranta ja verenvuotokomplikaatiot

Lepäntalo, A., 2019, In : Suomen lääkärilehti. 74, 8, p. 469-472 4 p.

Research output: Contribution to journalArticleProfessional

Antilymphocyte globulin for matched sibling donor transplantation in patients with myelofibrosis

Robin, M., Chevret, S., Koster, L., Wolschke, C., Yakoub-Agha, I., Bourhis, J. H., Chevallier, P., Cornelissen, J. J., Remenyi, P., Maertens, J., Poire, X., Craddock, C., Socie, G., Itälä-Remes, M., Schouten, H. C., Marchand, T., Passweg, J., Blaise, D., Damaj, G., Ozkurt, Z. N. & 7 othersZuckerman, T., Cluzeau, T., Labussiere-Wallet, H., Cammenga, J., McLornan, D., Chalandon, Y. & Kroger, N., 31 May 2019, In : Haematologica. 104, 6, p. 1230-1236 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

A prospective non-interventional study on the impact of transfusion burden and related iron toxicity on outcome in myelodysplastic syndromes undergoing allogeneic hematopoietic cell transplantation

Cremers, E. M. P., de Witte, T., de Wreede, L., Eikema, D-J., Koster, L., van Biezen, A., Finke, J., Socie, G., Beelen, D., Maertens, J., Nagler, A., Kobbe, G., Ziagkos, D., Itälä-Remes, M., Gedde-Dahl, T., Sierra, J., Niederwieser, D., Ljungman, P., Beguin, Y., Ozkurt, Z. N. & 4 othersAnagnostopoulos, A., Jindra, P., Robin, M. & Kröger, N., 10 Apr 2019, In : Leukemia & lymphoma. 10 p.

Research output: Contribution to journalArticleScientificpeer-review

A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease

Van Horebeek, L., Hilven, K., Mallants, K., Van Nieuwenhuijze, A., Kelkka, T., Savola, P., Mustjoki, S., Schlenner, S. M., Liston, A., Dubois, B. & Goris, A., 15 Apr 2019, In : Human Molecular Genetics. 28, 8, p. 1369-1380 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Assessing the utilization of the decision to implement a palliative goal for the treatment of cancer patients during the last year of life at Helsinki University Hospital: a historic cohort study

Hirvonen, O. M., Leskela, R-L., Gronholm, L., Haltia, O., Rissanen, A., Tyynela-Korhonen, K., Rahko, E. K., Lehto, J. T. & Saarto, T., 5 Sep 2019, In : Acta Oncologica. 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Boron neutron capture therapy for locally recurrent head and neck squamous cell carcinoma: An analysis of dose response and survival

Koivunoro, H., Kankaanranta, L., Seppälä, T., Haapaniemi, A., Mäkitie, A. & Joensuu, H., Aug 2019, In : Radiotherapy and Oncology. 137, p. 153-158 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Breast cancer outcome prediction with tumour tissue images and machine learning

Turkki, R., Byckhov, D., Lundin, M., Isola, J., Nordling, S., Kovanen, P. E., Verrill, C., von Smitten, K., Joensuu, H., Lundin, J. & Linder, N., Aug 2019, In : Breast Cancer Research and Treatment. 177, 1, p. 41-52 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Cancer Patients' Symptom Burden and Health-related Quality of Life (HRQoL) at Tertiary Cancer Center from 2006 to 2013: A Cross-sectional Study

Kokkonen, K., Tasmuth, T., Lehto, J. T., Kautiainen, H., Elme, A., Jaaskelainen, A-S. & Saarto, T., Jan 2019, In : Anticancer Research. 39, 1, p. 271-277 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

CAR-T-soluhoito - mitä ja millä hinnalla?

Leppä, S. & Vettenranta, K., 2019, In : Duodecim. 135, 12, p. 1202-1206 5 p.

Research output: Contribution to journalArticleProfessional

Characterization of an X-chromosome-linked telomere biology disorder in females with DKC1 mutation

Hirvonen, E. A. M., Peuhkuri, S., Norberg, A., Degerman, S., Hannula-Jouppi, K., Välimaa, H., Kilpivaara, O. & Wartiovaara-Kautto, U., Jan 2019, In : Leukemia. 33, 1, p. 275-278 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Characterization of polydactyly chondrocytes and their use in cartilage engineering

Cavalli, E., Levinson, C., Hertl, M., Broguiere, N., Brück, O., Mustjoki, S., Gerstenberg, A., Weber, D., Salzmann, G., Steinwachs, M., Barreto, G. & Zenobi-Wong, M., 12 Mar 2019, In : Scientific Reports. 9, 15 p., 4275.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Clinical and morphological practices in the diagnosis of transplant-associated microangiopathy: a study on behalf of Transplant Complications Working Party of the EBMT

Moiseev, I. S., Tsvetkova, T., Aljurf, M., Alnounou, R. M., Bogardt, J., Chalandon, Y., Drokov, M. Y., Dvirnyk, V., Faraci, M., Friis, L. S., Giglio, F., Greinix, H. T., Kornblit, B. T., Koelper, C., Koenecke, C., Lewandowski, K., Niederwieser, D., Passweg, J. R., Peczynski, C., Penack, O. & 15 othersPeric, Z., Piekarska, A., Ronchi, P. E., Rovo, A., Rzepecki, P., Scuderi, F., Sigrist, D., Siitonen, S. M., Stoelzel, F., Sulek, K., Tsakiris, D. A., Wilkowojska, U., Duarte, R. F., Ruutu, T. & Basak, G. W., Jul 2019, In : Bone Marrow Transplantation. 54, 7, p. 1022-1028 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Clinical features and outcome of the patients with sinonasal tract diffuse large B-cell lymphoma in the pre-rituximab and rituximab eras

Vähämurto, P., Mannisto, S., Pollari, M., Karjalainen-Lindsberg, M-L., Mäkitie, A. A. & Leppä, S., Jun 2019, In : European Journal of Haematology. 102, 6, p. 457-464 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Comparison of FLAMSA-based reduced intensity conditioning with treosulfan/fludarabine conditioning for patients with acute myeloid leukemia: an ALWP/EBMT analysis

Sheth, V., Labopin, M., Canaani, J., Volin, L., Brecht, A., Ganser, A., Mayer, J., Labussiere-Wallet, H., Bittenbring, J., Shouval, R., Savani, B., Mohty, M. & Nagler, A., Apr 2019, In : Bone Marrow Transplantation. 54, 4, p. 531-539 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Computational Analysis of HLA-presentation of Non-synonymous Recipient Mismatches Indicates Effect on the Risk of Chronic Graft-vs.-Host Disease After Allogeneic HSCT

Ritari, J., Hyvärinen, K., Koskela, S., Niittyvuopio, R., Nihtinen, A., Salmenniemi, U., Putkonen, M., Volin, L., Kwan, T., Pastinen, T., Itälä-Remes, M. & Partanen, J., 16 Jul 2019, In : Frontiers in Immunology. 10, 9 p., 1625.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Constitutively active GSK3 beta as a means to bolster dendritic cell functionality in the face of tumor-mediated immune suppression

Gonzalez, M. L., Oosterhoff, D., Lindenberg, J. J., Milenova, I., Lougheed, S. M., Martianez, T., Dekker, H., Quixabeira, D. C. A., Hangalapura, B., Joore, J., Piersma, S. R., Cervera-Carrascon, V., Santos, J. M., Scheper, R. J., Verheul, H. M. W., Jimenez, C. R., Van De Ven, R., Hemminki, A., Van Beusechem, V. W. & De Gruijl, T. D., 3 Oct 2019, In : OncoImmunology. 8, 10, 18 p., e1631119.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Costs in Different States of Breast Cancer

Roine, E., Farkkila, N., Sintonen, H., Taari, K., Roine, R. P. & Saarto, T., Jan 2019, In : Anticancer Research. 39, 1, p. 353-359 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Craniomaxillofacial osteosarcoma - The role of surgical margins

Kontio, R., Hagström, J., Lindholm, P., Böhling, T., Sampo, M., Mesimäki, K., Saarilahti, K., Koivunen, P. & Mäkitie, A. A., Jun 2019, In : Journal of Cranio-Maxillo-Facial Surgery. 47, 6, p. 922-925 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Dasatinib and navitoclax act synergistically to target NUP98-NSD1(+)/FLT3-ITD+ acute myeloid leukemia

Kivioja, J. L., Thanasopoulou, A., Kumar, A., Kontro, M., Yadav, B., Majumder, M. M., Javarappa, K. K., Eldfors, S., Schwaller, J., Porkka, K. & Heckman, C. A., Jun 2019, In : Leukemia. 33, 6, p. 1360-1372 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Differences in the risk of stroke, bleeding events, and mortality between female and male patients with atrial fibrillation during warfarin therapy

Penttilä, T., Lehto, M., Niiranen, J., Mehtälä, J., Khanfir, H., Lassila, R. & Raatikainen, P., Jan 2019, In : European Heart Journal - Cardiovascular Pharmacotherapy. 5, 1, p. 29-36 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Does Decision-making in End-of-life Care Differ Between Graduating Medical Students and Experienced Physicians?

Alminoja, A., Piili, R. P., Hinkka, H., Metsänoja, R., Hirvonen, O., Tyynelä-Korhonen, K., Kaleva-Kerola, J., Saarto, T., Kellokumpu-Lehtinen, P-L. I. & Lehto, J. T., 2019, In : In Vivo. 33, 3, p. 903-909 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease

Keskitalo, S., Haapaniemi, E. M., Glumoff, V., Liu, X., Lehtinen, V., Fogarty, C., Rajala, H., Chiang, S. C., Mustjoki, S., Kovanen, P., Lohi, J., Bryceson, Y. T., Seppänen, M., Kere, J., Heiskanen, K. & Varjosalo, M., 27 Jul 2019, In : Npj genomic medicine. 4, 1

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

EBMT prospective observational study on allogeneic hematopoietic stem cell transplantation in T-prolymphocytic leukemia (T-PLL)

Wiktor-Jedrzejczak, W., Drozd-Sokolowska, J., Eikema, D. J., Hoek, J., Potter, M., Wulf, G., Sellner, L., Ljungman, P., Chevallier, P., Volin, L., Koc, Y., Martin, S., Bunjes, D., Rovira, M., Itala-Remes, M., Foa, R., Deconinck, E., Gedde-Dahl, T., Cornelissen, J., Collin, M. & 12 othersBrecht, A., Patel, A., de Groot, M., Remenyi, P., Nagler, A., Finke, J., Turlure, P., Iacobelli, S., van Biezen, A., Schetelig, J., Kroeger, N. & Dreger, P., Sep 2019, In : Bone Marrow Transplantation. 54, 9, p. 1391-1398 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Effectiveness of a 12-month Exercise Intervention on Physical Activity and Quality of Life of Breast Cancer Survivors; Five-year Results of the BREX-study

Penttinen, H., Utriainen, M., Kellokumpu-Lehtinen, P-L., Raitanen, J., Sievänen, H., Nikander, R., Blomqvist, C., Huovinen, R., Vehmanen, L. & Saarto, T., 2019, In : In Vivo. 33, 3, p. 881-888 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of Genetic Modifications on Physical and Functional Titers of Adenoviral Cancer Gene Therapy Constructs

Heiniö, C., Sorsa, S., Siurala, M., Grönberg-Vähä-Koskela, S., Havunen, R., Haavisto, E., Koski, A., Hemminki, O., Zafar, S., Cervera-Carrascon, V., Munaro, E., Kanerva, A. & Hemminki, A., 1 Jun 2019, In : Human Gene Therapy. 30, 6, p. 740-752 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of Wilms tumor histology on response to neoadjuvant chemotherapy

Taskinen, S., Leskinen, O., Lohi, J., Koskenvuo, M. & Taskinen, M., Apr 2019, In : Journal of Pediatric Surgery. 54, 4, p. 771-774 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Estrogen receptor beta expression correlates with proliferation in desmoid tumors

Santti, K., Ihalainen, H., Rönty, M., Karlsson, C., Haglund, C., Sampo, M., Tarkkanen, M. & Blomqvist, C., Jun 2019, In : Journal of Surgical Oncology. 119, 7, p. 873-879 7 p.

Research output: Contribution to journalArticleScientificpeer-review

European Society of Surgical Oncology's strategy for clinical research: Paving the way for a culture of research in cancer surgery

European Soc Surgical Oncology, Sep 2019, In : European Journal of Surgical Oncology. 45, 9, p. 1515-1519 5 p.

Research output: Contribution to journalArticleScientificpeer-review

EUSOMA position regarding breast implant associated anaplastic large cell lymphoma (BIA-ALCL) and the use of textured implants

Cardoso, M. J., Wyld, L., Rubio, I. T., Leidenius, M., Curigliano, G., Cutuli, B., Marotti, L. & Biganzoli, L., Apr 2019, In : Breast. 44, p. 90-93 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Evaluation of a standardized protocol for thrombin generation using the calibrated automated thrombogram: A Nordic study

Ljungkvist, M., Strandberg, K., Berntorp, E., Chaireti, R., Holme, P. A., Larsen, O. H., Lassila, R., Jouppila, A., Szanto, T. & Zetterberg, E., Mar 2019, In : Haemophilia. 25, 2, p. 334-342 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Evolving Clinical Picture of Renal Cell Carcinoma: A Population-Based Study from Helsinki

Erkkilä, K., Tornberg, S. V., Järvinen, P., Järvinen, R., Kilpeläinen, T. P., Visapää, H., Hervonen, P., Taari, K. & Nisen, H., 2019, In : Urologia internationalis. 102, 4, p. 390-398 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Extent of resection and long-term survival of pineal region tumors in Helsinki Neurosurgery

Choque-Velasquez, J., Resendiz-Nieves, J., Jahromi, B. R., Colasanti, R., Raj, R., Vehviläinen, J., Tynninen, O., Collan, J., Niemelä, M. & Hernesniemi, J., 30 Jul 2019, In : World Neurosurgery.

Research output: Contribution to journalArticleScientificpeer-review

Familial Associations of Colon and Rectal Cancers With Other Cancers

Yu, H., Hemminki, A., Sundquist, K. & Hemminki, K., Feb 2019, In : Diseases of the Colon & Rectum. 62, 2, p. 189-195 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Family Mismatched Allogeneic Stem Cell Transplantation for Myelofibrosis: Report from the Chronic Malignancies Working Party of European Society for Blood and Marrow Transplantation

Raj, K., Eikema, D-J., McLornanl, D. P., Olavarria, E., Bloke, H-J., Bregante, S., Ciceri, F., Passweg, J., Ljungman, P., Schaap, N., Carlson, K., Zuckerman, T., de Wreede, L. C., Volin, L., Koc, Y., Luis Diez-Martin, J., Brossart, P., Wolf, D., Blaise, D., Di Bartolomeo, P. & 5 othersVitek, A., Robin, M., Yakoub-Agha, I., Chalandon, Y. & Kroger, N., Mar 2019, In : Biology of Blood and Marrow Transplantation. 25, 3, p. 522-528 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Feasibility of MRI-only photon and proton dose calculations for pediatric patients with abdominal tumors

Guerreiro, F., Koivula, L., Seravalli, E., Janssens, G. O., Maduro, J. H., Brouwer, C. L., Korevaar, E. W., Knopf, A. C., Korhonen, J. & Raaymakers, B. W., Mar 2019, In : Physics in Medicine and Biology. 64, 5, 13 p., 055010.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Functional Outcome Measurement in Patients with Lower-Extremity Soft Tissue Sarcoma: A Systematic Literature Review

Kask, G., Barner-Rasmussen, I., Repo, J. P., Kjäldman, M., Kilk, K., Blomqvist, C. & Tukiainen, E. J., 12 Aug 2019, In : Annals of Surgical Oncology.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Genetic architecture of human plasma lipidome and its link to cardiovascular disease

FinnGen Project, 24 Sep 2019, In : Nature Communications. 10, 1, 14 p., 4329.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

GC-HBOC Study Collaborators, GEMO Study Collaborators, EMBRACE Collaborators, HEBON Investigators, BCFR Investigators, ABCTB Investigators , Ferreira, M. A., Gamazon, E. R., Aittomäki, K., Blomqvist, C., Kiiski, J. I. & Nevanlinna, H., 15 Apr 2019, In : Nature Communications. 10, 18 p., 1741.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Genome-wide association study of germline variants and breast cancer-specific mortality

NBCS Collaborators, Escala-Garcia, M., Guo, Q., Doerk, T., Blomqvist, C., Khan, S., Kiiski, J. I. & Nevanlinna, H., 19 Mar 2019, In : British Journal of Cancer. 120, 6, p. 647-657 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Genomic prediction of relapse in recipients of allogeneic haematopoietic stem cell transplantation

Ritari, J., Hyvärinen, K., Koskela, S., Itälä-Remes, M., Niittyvuopio, R., Nihtinen, A., Salmenniemi, U., Putkonen, M., Volin, L., Kwan, T., Pastinen, T. & Partanen, J., Jan 2019, In : Leukemia. 33, 1, p. 240-248 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Glioblastoma survival is improving despite increasing incidence rates: a nationwide study between 2000 and 2013 in Finland

Korja, M., Raj, R., Seppä, K., Luostarinen, T., Malila, N., Seppälä, M., Mäenpää, H. & Pitkäniemi, J., Mar 2019, In : Neuro-Oncology. 21, 3, p. 370-379 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Neurology Collaborators, Feigin, V. L., Nichols, E., Meretoja, A., Meretoja, T. J., Shiri, R. & Weiderpass, E., May 2019, In : Lancet Neurology. 18, 5, p. 459-480 22 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Global, regional, and national burden of traumatic brain injury and spinal cord injury, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Traumatic Brain Injury Sp, Jan 2019, In : Lancet Neurology. 18, 1, p. 56-87 32 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File