Projects per year
Organization profile
From basic research on dsRNA viruses to RNA-based antivirals and crop protectants
Our research aims at molecular level understanding of viral replication mechanisms and self-assembly pathways. These functions are critical in viral disease development and important targets for antivirals. The basic molecular virology research carried out in our laboratory has also led to innovations in the field of RNA interference facilitating the development of new antiviral therapeutics and novel crop protection strategies. Read more on our website.
International and National Collaboration
Publications and projects within past five years.
Profiles
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Veera E Brusila
- Molecular and Translational Virology
- Doctoral Programme in Sustainable Use of Renewable Natural Resources
Person: Doctoral Researcher, Teaching and research personnel
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Katri Eskelin
- Department of Food and Nutrition - Title of Docent
- Molecular and Integrative Biosciences Research Programme - University Researcher
- Molecular and Translational Virology
Person: U3 Research and teaching staff, UH , Teaching and research personnel
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Sari Susanna Mäntynen
- Molecular and Integrative Biosciences Research Programme - Postdoctoral Researcher
- Molecular and Translational Virology
- Doctoral Programme in Microbiology and Biotechnology - Supervisor for doctoral programme
Person: U2 Teaching and research staff
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Minna Poranen
- Molecular and Integrative Biosciences Research Programme - Senior University Lecturer
- Molecular and Translational Virology
- Doctoral Programme in Biomedicine - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Microbiology and Biotechnology - Supervisor for doctoral programme
- Doctoral Programme in Sustainable Use of Renewable Natural Resources - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH , Teaching and research personnel
Equipment
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Instruct-ERIC Centre Finland
Sarah Butcher (Manager), Hanna M Oksanen (Other), Minna Poranen (Other), Katri Eskelin (Other), Perttu Permi (Other), Markku Varjosalo (Other), Lari Lehtiö (Other) & Juha Rouvinen (Other)
Faculty of Biological and Environmental SciencesFacility/equipment: Core Facility
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Instruct-HiLIFE Biomolecular Complex Purification Core Facility (Biocomplex)
Minna Marjetta Poranen (Manager), Hanna Maarit Oksanen (Other) & Katri Johanna Eskelin (Other)
Faculty of Biological and Environmental SciencesFacility/equipment: Core Facility
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Molecular Interactions - Biacore T100
Minna Poranen (Manager) & Maria Aatonen (Operator)
Facility/equipment: Equipment
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Structural Biology Finland (FINStruct)
Sarah Butcher (Manager), Hanna M Oksanen (Other), Minna Poranen (Other), Katri Eskelin (Other), Tommi Kajander (Other), Perttu Permi (Other), Lari Lehtiö (Other), Juha Rouvinen (Other), Tiina A Salminen (Other) & Anastassios Papageorgiou (Other)
Faculty of Biological and Environmental SciencesFacility/equipment: Core Facility
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Integrated Structural Biology Infrastructure-European Research Infrastructure Consortium (Instruct-ERIC) / Consortium FINStruct and Instruct-ERIC
Butcher, S., Poranen, M., Varjosalo, M., Kajander, T., Oksanen, H. M., Eskelin , K., Lehtiö, L., Salminen, T. A. & Papageorgiou, A. C.
01/01/2022 → 31/12/2026
Project: Academy of Finland: Research infrastructure
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SusCrop - ERA-NET, Target-specific RNA-based bioprotectants for sustainable crop production in a changing climate
Kogel, K., Patel, A., Heinlein, M., Poranen, M., Eskelin , K., Levanova, A. & Westerholm, T. T.
01/06/2021 → 31/05/2024
Project: Ministry funding
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Structural Biology Finland (FINStruct) & Instruct-ERIC Centre FI / Research Infrastructure Roadmap 2021-2024
Butcher, S., Poranen, M., Kajander, T., Iwai, H., Varjosalo, M., Lehtiö, L., Rouvinen, J., Salminen, T. A., Papageorgiou, A. C., Oksanen, H. M. & Eskelin , K.
01/01/2021 → 31/12/2024
Project: Academy of Finland: Research infrastructure
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Instruct-HiLIFE: Integrated structural cell biology research infrastructure platform, HiLIFE, University of Helsinki
Poranen, M., Butcher, S., Iwai, H., Kajander, T., Oksanen, H. M. & Eskelin , K.
01/01/2021 → 31/12/2024
Project: Other project
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Environmental RNAi for pathogen control
Poranen, M., Levanova, A., Marttila, H., Mäntynen, S. S., Sun, X. & Westerholm, T. T.
SUOMEN AKATEMIA Vähäkylä Leena
01/09/2020 → 31/08/2024
Project: Academy of Finland: Academy Project
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Abolishment of morphology-based taxa and change to binomial species names: 2022 taxonomy update of the ICTV bacterial viruses subcommittee
Turner, D., Shkoporov, A. N., Lood, C., Millard, A. D., Dutilh, B. E., Alfenas-Zerbini, P., van Zyl, L. J., Aziz, R. K., Oksanen, H. M., Poranen, M., Kropinski, A. M., Barylski, J., Brister, J. R., Chanisvili, N., Edwards, R., Enault, F., Gillis, A., Knezevic, P., Krupovic, M., Kurtboke, I., & 16 others, 2023, In: Archives of Virology. 168, 74Research output: Contribution to journal › Review Article › peer-review
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Four principles to establish a universal virus taxonomy
Simmonds, P., Adriaenssens, E. M., Murilo Zerbini, F., Abrescia, N. G. A., Aiewsakun, P., Alfenas-Zerbini, P., Bao, Y., Barylski, J., Drosten, C., Duffy, S., Paul Duprex, W., Dutilh, B. E., Elena, S. F., García, M. L., Junglen, S., Katzourakis, A., Koonin, E. V., Krupovic, M., Kuhn, J. H., Lambert, A. J., & 23 others, Feb 2023, In: PLoS Biology. 21, 2, 23 p., e3001922.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV‐1
Lasanen, T., Frejborg, F., Lund, L., Nyman, M., Orpana, J., Habib, H., Alaollitervo, S., Levanova, A., Poranen, M., Hukkanen, V. & Kalke, K., 2023, In: Smart Medicine. 2, e20230009.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Analysis and purification of ssRNA and dsRNA molecules using asymmetrical flow field flow fractionation
Eskelin, K., Lampi, M., Coustau, C., Imani, J., Kogel, K-H. & Poranen, M., 8 Nov 2022, In: Journal of Chromatography. A. 1683, 15 p., 463525.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Archaeal viruses: production of virus particles and vesicle-like viruses and purification using asymmetrical flow field-flow fractionation
Eskelin, K. & Oksanen, H. M., 21 Sep 2022, Methods in Molecular Biology - Archaea: methods and protocols. Ferreira-Cerca, S. (ed.). Humana New York, NY, p. 449-465 (Methods in Molecular Biology; vol. 2522).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific › peer-review
Activities
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PLoS Pathogens (Journal)
Minna Poranen (Reviewer)
2023Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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Presentation for high school students
Minna Poranen (Invited speaker)
2023Activity: Talk or presentation types › Oral presentation
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Presentation for the Plant Protection Advisory Council of the Ministry of Agriculture and Forestry
Minna Poranen (Invited speaker)
12 May 2023Activity: Talk or presentation types › Oral presentation
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Helsinki Light Scattering Workshop: Enhancing Structural Biology andGene Delivery Applications with Light Scattering
Minna Poranen (Attendee)
10 May 2023Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Virology Days 2023
Minna Poranen (Attendee)
30 Mar 2023 → 31 Mar 2023Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Prizes
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Excellence in Master Thesis Supervision Award, 2005
Poranen, Minna (Recipient), 23 Feb 2006
Prize: Prizes and awards
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Supervision work acknowledgement from the China Scholarship Council, 2014
Poranen, Minna (Recipient), 2014
Prize: Prizes and awards
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Viikki Biocenter Dissertation Prize, 2000
Poranen, Minna (Recipient), 20 Nov 2000
Prize: Prizes and awards
Press/Media
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-UNIVERSITY OF HELSINKI: Unveiling how the genome has condensed itself inside the virus
30/05/2019
1 item of Media coverage
Press/Media: Press / Media
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Cryo-EM Reveals How a Virus Packages Its Genome
30/05/2019
1 item of Media coverage
Press/Media: Press / Media
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Revealing how the genome has condensed inside the virus.
30/05/2019
1 item of Media coverage
Press/Media: Press / Media
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Unveiling how the genome has condensed itself inside the virus
29/05/2019
5 items of Media coverage
Press/Media: Press / Media
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