Publications 1977 2019

2019

Activation of P2X7 Receptors in Peritoneal and Meningeal Mast Cells Detected by Uptake of Organic Dyes: Possible Purinergic Triggers of Neuroinflammation in Meninges

Nurkhametova, D., Kudryavtsev, I., Guselnikova, V., Serebryakova, M., Giniatullina, R. R., Wojciechowski, S., Tore, F., Rizvanov, A., Koistinaho, J., Malm, T. & Giniatullin, R., 13 Feb 2019, In : Frontiers in Cellular Neuroscience. 13

Research output: Contribution to journalArticleScientificpeer-review

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Activation of the TRKB receptor mediates the panicolytic-like effect of the NOS inhibitor aminoguanidine

Ribeiro, D. E., Casarotto, P. C., Júnior, A. S., Fernandes, G. G., Pinheiro, L. C., dos Santos, J. E. T., Júnior, H. Z., Guimarães, F. S., Joca, S. R. L. & Biojone, C., 13 Apr 2019, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry.

Research output: Contribution to journalArticleScientificpeer-review

Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling

Richter, M., Murtaza, N., Scharrenberg, R., White, S. H., Johanns, O., Walker, S., Yuen, R. K. C., Schwanke, B., Bedurftig, B., Henis, M., Scharf, S., Kraus, V., Dork, R., Hellmann, J., Lindenmaier, Z., Ellegood, J., Hartung, H., Kwan, V., Sedlacik, J., Fiehler, J. & 7 othersSchweizer, M., Lerch, J. P., Hanganu-Opatz, I. L., Morellini, F., Scherer, S. W., Singh, K. K. & de Anda, F. C., Sep 2019, In : Molecular Psychiatry. 24, 9, p. 1329-1350 22 p.

Research output: Contribution to journalArticleScientificpeer-review

Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms

Oksanen, M., Lehtonen, S., Jaronen, M., Goldsteins, G., Hämäläinen, R. H. & Koistinaho, J., 23 Apr 2019, In : Cellular and Molecular Life Sciences. 76, 14, p. 2739-2760 22 p.

Research output: Contribution to journalArticleScientificpeer-review

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Attention, memory and preference for direct and indirect print advertisements

Simola, J., Kuisma, J. & Kaakinen, J., 17 Jun 2019, In : Journal of Business Research. https://doi.org/10.1016/j.jbusres.2019.06.028.

Research output: Contribution to journalArticleScientificpeer-review

A variant in MRPS14 (uS14m) causes perinatal hypertrophic cardiomyopathy with neonatal lactic acidosis, growth retardation, dysmorphic features and neurological involvement

Jackson, C. B., Huemer, M., Bolognini, R., Martin, F., Szinnai, G., Donner, B. C., Richter, U., Battersby, B. J., Nuoffer, J-M., Suomalainen, A. & Schaller, A., 15 Feb 2019, In : Human Molecular Genetics. 28, 4, p. 639-649 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Bumetanide Prevents Brain Trauma-Induced Depressive-Like Behavior

Goubert, E., Altvater, M., Rovira, M-N., Khalilov, I., Mazzarino, M., Sebastiani, A., Schaefer, M. K. E., Rivera, C. & Pellegrino, C., 5 Feb 2019, In : Frontiers in Molecular Neuroscience. 12

Research output: Contribution to journalArticleScientificpeer-review

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CDNF Protein Therapy in Parkinson’s Disease

Huttunen, H. J. & Saarma, M., 4 Apr 2019, In : Cell Transplantation. 28, 4, p. 349-366 18 p.

Research output: Contribution to journalArticleScientificpeer-review

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Central nervous system lymphatic unit, immunity, and epilepsy: Is there a link?

Noé, F. M. & Marchi, N., 13 Jan 2019, In : Epilepsia Open. 4, 1, p. 30-39 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice

Schob, C., Morellini, F., Ohana, O., Bakota, L., Hrynchak, M. V., Brandt, R., Brockmann, M. D., Cichon, N., Hartung, H., Hanganu-Opatz, I. L., Kraus, V., Scharf, S., Herrmans-Borgmeyer, I., Schweizer, M., Kuhl, D., Wöhr, M., Vörckel, K. J., Calzada-Wack, J., Fuchs, H., Gailus-Durner, V. & 4 othersHrabě de Angelis, M., Garner, C. C., Kreienkamp, H-J. & Kindler, S., 2019, In : Translational Psychiatry. 9, 1

Research output: Contribution to journalArticleScientificpeer-review

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Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes

Garcia-Garcia, A., Korn, C., Garcia-Fernandez, M., Domingues, O., Villadiego, J., Martin-Perez, D., Isern, J., Bejarano-Garcia, J. A., Zimmer, J., Perez-Simon, J. A., Toledo-Aral, J. J., Michel, T., Airaksinen, M. S. & Mendez-Ferrer, S., 17 Jan 2019, In : Blood. 133, 3, p. 224-236 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors

Diniz, C. R. A. F., Biojone, C., Joca, S. R. L., Rantamäki, T., Castren, E., Guimaraes, F. S. & Casarotto, P. C., 21 Feb 2019, In : PeerJ. 7, 21 p., 6493.

Research output: Contribution to journalArticleScientificpeer-review

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Dysfunction of Cellular Proteostasis in Parkinson's Disease

Lehtonen, S., Sonninen, T-M., Wojciechowski, S., Goldsteins, G. & Koistinaho, J., 10 May 2019, In : Frontiers in Neuroscience. 13, 19 p., 457.

Research output: Contribution to journalReview ArticleScientificpeer-review

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Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury

Poyhonen, S., Er, S., Domanskyi, A. & Airavaara, M., 26 Apr 2019, In : Frontiers in Physiology. 10, 20 p., 486.

Research output: Contribution to journalReview ArticleScientificpeer-review

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Experiments done in Black-6 mice: what does it mean?

Åhlgren, J. K. & Voikar, V., Apr 2019, In : Lab Animal. 10.1038/s41684-019-0288-8.

Research output: Contribution to journalArticleScientificpeer-review

GluA4 Dependent Plasticity Mechanisms Contribute to Developmental Synchronization of the CA3-CA1 Circuitry in the Hippocampus

Atanasova, T., Kharybina, Z., Kaarela, T. A. M., Huupponen, J. T., Luchkina, N., Taira, T. P. & Lauri, S. E., Mar 2019, In : Neurochemical Research. 44, 3, p. 562–571 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Housing mice in the individually ventilated or open cages—Does it matter for behavioral phenotype?

Åhlgren, J. & Voikar, V., Sep 2019, In : Genes, Brain and Behavior. 18, 7, 12 p., 12564.

Research output: Contribution to journalArticleScientificpeer-review

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Instability of the mitochondrial alanyl-tRNA synthetase underlies fatal infantile-onset cardiomyopathy

Sommerville, E. W., Zhou, X-L., Olahova, M., Jenkins, J., Euro, L., Konovalova, S., Hilander, T., Pyle, A., He, L., Habeebu, S., Saunders, C., Kelsey, A., Morris, A. A. M., McFarland, R., Suomalainen, A., Gorman, G. S., Wang, E-D., Thiffault, I., Tyynismaa, H. & Taylor, R. W., 15 Jan 2019, In : Human Molecular Genetics. 28, 2, p. 258-268 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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In vivo Two-Photon Imaging of Anesthesia-Specific Alterations in Microglial Surveillance and Photodamage-Directed Motility in Mouse Cortex

Sun, W., Suzuki, K., Toptunov, D., Stoyanov, S., Yuzaki, M., Khiroug, L. & Dilyatev, A., 7 May 2019, In : Frontiers in Neuroscience. 13, 12 p., 421.

Research output: Contribution to journalArticleScientificpeer-review

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Kainate receptor auxiliary subunit NETO2 is required for normal fear expression and extinction

Mennesson, M., Rydgren, E., Lipina, T., Sokolowska, E., Kulesskaya, N., Morello, F., Ivakine, E., Voikar, V., Risbrough, V., Partanen, J. & Hovatta, I., Oct 2019, In : Neuropsychopharmacology. 44, 11, p. 1855-1866 12 p.

Research output: Contribution to journalArticleScientificpeer-review

KCC2-Mediated Cl- Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice

Spoljaric, I., Spoljaric, A., Mavrovic, M., Seja, P., Puskarjov, M. & Kaila, K., 29 Jan 2019, In : Cell Reports. 26, 5, p. 1073-+ 12 p.

Research output: Contribution to journalArticleScientificpeer-review

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Large-scale brain modes reorganize between infant sleep states and carry prognostic information for preterms

Tokariev, A., Roberts, J. A., Zalesky, A., Zhao, X., Vanhatalo, S., Breakspear, M. & Cocchi, L., 13 Jun 2019, In : Nature Communications. 10, 9 p., 2619.

Research output: Contribution to journalArticleScientificpeer-review

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More dampened monocytic Toll-like receptor 4 response to lipopolysaccharide and its association with cognitive function in Chinese Han first-episode patients with schizophrenia

Chen, S., Tian, L., Chen, N., Xiu, M-H., Wang, Z-R., Wang, Y-C., Tan, Y-L. & Wang, C-Y., Apr 2019, In : Schizophrenia Research. 206, p. 300-306 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Multi-omics analysis identifies mitochondrial pathways associated with anxiety-related behavior

Misiewicz, Z., Iurato, S., Kulesskaya, N., Salminen, L., Rodrigues, L., Maccarrone, G., Martins, J., Czamara, D., Laine, M. A., Sokolowska, E., Trontti, K., Rewerts, C., Novak, B., Volk, N., Park, D. I., Jokitalo, E., Paulin, L., Auvinen, P., Voikar, V., Chen, A. & 3 othersErhardt, A., Turck, C. W. & Hovatta, I., 26 Sep 2019, In : PLoS Genetics. 15, 9, p. e1008358

Research output: Contribution to journalArticleScientificpeer-review

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NETO1 regulates postsynaptic Kainate receptors in CA3 interneurons during circuit maturation

Orav, E., 2019.

Research output: Conference materialsPosterResearchpeer-review

NETO1 Regulates Postsynaptic Kainate Receptors in CA3 Interneurons During Circuit Maturation

Orav, E., Dowavic, I., Huupponen, J., Taira, T. & Lauri, S., 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticleScientificpeer-review

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Neuronal activation stimulates cytomegalovirus promoter-driven transgene expression

Bäck, S., Dossat, A., Parkkinen, I., Koivula, P., Airavaara, M., Richie, C. T., Chen, Y-H., Wang, Y. & Harvey, B. K., 2019, In : Molecular therapy-Methods & clinical development.

Research output: Contribution to journalArticleScientificpeer-review

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Neurotrophin receptor Ntrk2b function in the maintenance of dopamine and serotonin neurons in zebrafish

Sahu, M. P., Pazos-Boubeta, Y., Pajanoja, C., Rozov, S., Panula, P. & Castren, E., 14 Feb 2019, In : Scientific Reports. 9, 13 p., 2036.

Research output: Contribution to journalArticleScientificpeer-review

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New enzymes of dopamine metabolism in the zebrafish Danio rerio

Semenova, S., 2019, Helsinki: [S. Semenova]. 89 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Overlapping anatomical networks convey cross-modal suppression in the sighted and co-activation of "visual" and auditory cortex in the blind

Anurova, I., Carlson, L. S. & Rauschecker, J. P., 2019, (Accepted/In press) In : Cerebral Cortex.

Research output: Contribution to journalArticleScientificpeer-review

Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke

Kolosowska, N., Keuters, M. H., Wojciechowski, S., Keksa-Goldsteine, V., Laine, M., Malm, T., Goldsteins, G., Koistinaho, J. & Dhungana, H., 1 Aug 2019, In : Neurotherapeutics.

Research output: Contribution to journalArticleScientificpeer-review

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PPAR beta/delta-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1 Delta E9 astrocytes

Konttinen, H., Gureviciene, I., Oksanen, M., Grubman, A., Loppi, S., Huuskonen, M. T., Korhonen, P., Lampinen, R., Keuters, M., Belaya, I., Tanila, H., Kanninen, K. M., Goldsteins, G., Landreth, G., Koistinaho, J. & Malm, T., Jan 2019, In : Glia. 67, 1, p. 146-159 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Preterm Birth Changes Networks of Newborn Cortical Activity

Tokariev, A., Stjerna, S., Lano, A., Metsäranta, M., Palva, J. M. & Vanhatalo, S., Feb 2019, In : Cerebral Cortex. 29, 2, p. 814-826 13 p.

Research output: Contribution to journalArticleScientificpeer-review

PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

Konttinen, H., Cabral-da-Silva, M. E. C., Ohtonen, S., Wojciechowski, S., Shakirzyanova, A., Caligola, S., Giugno, R., Ishchenko, Y., Hernández, D., Fazaludeen, M. F., Eamen, S., Budia, M. G., Fagerlund, I., Scoyni, F., Korhonen, P., Huber, N., Haapasalo, A., Hewitt, A. W., Vickers, J., Smith, G. C. & 10 othersOksanen, M., Graff, C., Kanninen, K. M., Lehtonen, S., Propson, N., Schwartz, M. P., Pébay, A., Koistinaho, J., Ooi, L. & Malm, T., 12 Sep 2019, In : Stem cell reports.

Research output: Contribution to journalArticleScientificpeer-review

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Quantitative changes in perineuronal nets in development and posttraumatic condition

Lipachev, N., Arnst, N., Melnikova, A., Jäälinoja, H., Kochneva, A., Zhigalov, A., Kulesskaya, N., Aganov, A. V., Mavlikeev, M., Rauvala, H., Kiyasov, A. P. & Paveliev, M., Jun 2019, In : Journal of Molecular Histology. 50, 3, p. 203-216 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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Regeneration of Dopaminergic Neurons in Adult Zebrafish Depends on Immune System Activation and Differs for Distinct Populations

Caldwell, L. J., Davies, N. O., Cavone, L., Mysiak, K. S., Semenova, S. A., Panula, P., Armstrong, J. D., Becker, C. G. & Becker, T., 12 Jun 2019, In : Journal of Neuroscience. 39, 24, p. 4694-4713 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Resting state cross-frequency coupling networks in human electrophysiological recordings

Siebenhuehner, F., Wang, S. H., Arnulfo, G., Palva, S. O. & Palva, J. M., 23 Jan 2019, (Submitted) In : PLoS Biology.

Research output: Contribution to journalArticleScientificpeer-review

Sex-specific transcriptional and proteomic signatures in schizophrenia

Tiihonen, J., Koskuvi, M., Storvik, M., Hyotylainen, I., Gao, Y., Puttonen, K. A., Giniatullina, R., Poguzhelskaya, E., Ojansuu, I., Vaurio, O., Cannon, T. D., Lonnqvist, J., Therman, S., Suvisaari, J., Kaprio, J., Cheng, L., Hill, A. F., Lahteenvuo, M., Tohka, J., Giniatullin, R. & 2 othersLehtonen, S. & Koistinaho, J., 2 Sep 2019, In : Nature Communications. 10, 11 p., 3933.

Research output: Contribution to journalArticleScientificpeer-review

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Sub-membranous actin rings in the axon initial segment are resistant to the action of latrunculin

Abouelezz, A., Micinski, D., Lipponen, A. & Hotulainen, P., Sep 2019, In : Biological Chemistry. 400, 9, p. 1141-1146 6 p.

Research output: Contribution to journalArticleScientificpeer-review

The primate-specific peptide Y-P30 regulates morphological maturation of neocortical dendritic spines

Neumann, J. R., Dash-Wagh, S., Jack, A., Raek, A., Juengling, K., Hamad, M. I. K., Pape, H-C., Kreutz, M. R., Puskarjov, M. & Wahle, P., 13 Feb 2019, In : PLoS One. 14, 2, 23 p., 0211151.

Research output: Contribution to journalArticleScientificpeer-review

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The role of multi-scale phase synchronization and cross-frequency interactions in cognitive integration

Siebenhuehner, F., 16 Jan 2019, (Submitted)

Research output: ThesisDoctoral ThesisCollection of Articles

Transient modification of lin28b expression - Permanent effects on zebrafish growth

Leinonen, J. T., Chen, Y-C., Tukiainen, T., Panula, P. & Widen, E., 5 Jan 2019, In : Molecular and Cellular Endocrinology. 479, p. 61-70 10 p.

Research output: Contribution to journalArticleScientificpeer-review

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TrkB-ICD Fragment, Originating From BDNF Receptor Cleavage, Is Translocated to Cell Nucleus and Phosphorylates Nuclear and Axonal Proteins

Fonseca-Gomes, J., Jerónimo-Santos, A., Lesnikova, A., Casarotto, P., Castrén, E., Sebastião, A. M. & Diógenes, M. J., 1 Feb 2019, In : Frontiers in Molecular Neuroscience. 12

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2018

Aberrant Inclusion of a Poison Exon Causes Dravet Syndrome and Related SCN1A-Associated Genetic Epilepsies

EuroEPINOMICS Rare Epilepsy Syndro, Carvill, G. L. & Lehesjoki, A-E., 6 Dec 2018, In : American Journal of Human Genetics. 103, 6, p. 1022-1029 8 p.

Research output: Contribution to journalArticleScientificpeer-review

A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions

Nikkanen, J., Landoni, J. C., Balboa, D., Haugas, M., Partanen, J., Paetau, A., Isohanni, P., Brilhante, V. & Suomalainen, A., Jan 2018, In : EMBO molecular medicine. 10, 1, p. 13-21 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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