Publications 1977 2019

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2019

Activation of P2X7 Receptors in Peritoneal and Meningeal Mast Cells Detected by Uptake of Organic Dyes: Possible Purinergic Triggers of Neuroinflammation in Meninges

Nurkhametova, D., Kudryavtsev, I., Guselnikova, V., Serebryakova, M., Giniatullina, R. R., Wojciechowski, S., Tore, F., Rizvanov, A., Koistinaho, J., Malm, T. & Giniatullin, R., 13 Feb 2019, In : Frontiers in Cellular Neuroscience. 13

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Activation of the TRKB receptor mediates the panicolytic-like effect of the NOS inhibitor aminoguanidine

Ribeiro, D. E., Casarotto, P. C., Júnior, A. S., Fernandes, G. G., Pinheiro, L. C., dos Santos, J. E. T., Júnior, H. Z., Guimarães, F. S., Joca, S. R. L. & Biojone, C., 13 Apr 2019, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry.

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A variant in MRPS14 (uS14m) causes perinatal hypertrophic cardiomyopathy with neonatal lactic acidosis, growth retardation, dysmorphic features and neurological involvement

Jackson, C. B., Huemer, M., Bolognini, R., Martin, F., Szinnai, G., Donner, B. C., Richter, U., Battersby, B. J., Nuoffer, J-M., Suomalainen, A. & Schaller, A., 15 Feb 2019, In : Human Molecular Genetics. 28, 4, p. 639-649 11 p.

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Bumetanide Prevents Brain Trauma-Induced Depressive-Like Behavior

Goubert, E., Altvater, M., Rovira, M-N., Khalilov, I., Mazzarino, M., Sebastiani, A., Schaefer, M. K. E., Rivera, C. & Pellegrino, C., 5 Feb 2019, In : Frontiers in Molecular Neuroscience. 12

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CDNF Protein Therapy in Parkinson’s Disease

Huttunen, H. J. & Saarma, M., 4 Apr 2019, In : Cell Transplantation. 28, 4, p. 349-366 18 p.

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Central nervous system lymphatic unit, immunity, and epilepsy: Is there a link?

Noé, F. M. & Marchi, N., 13 Jan 2019, In : Epilepsia Open. 4, 1, p. 30-39 10 p.

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Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice

Schob, C., Morellini, F., Ohana, O., Bakota, L., Hrynchak, M. V., Brandt, R., Brockmann, M. D., Cichon, N., Hartung, H., Hanganu-Opatz, I. L., Kraus, V., Scharf, S., Herrmans-Borgmeyer, I., Schweizer, M., Kuhl, D., Wöhr, M., Vörckel, K. J., Calzada-Wack, J., Fuchs, H., Gailus-Durner, V. & 4 othersHrabě de Angelis, M., Garner, C. C., Kreienkamp, H-J. & Kindler, S., 2019, In : Translational Psychiatry. 9, 1

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Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes

Garcia-Garcia, A., Korn, C., Garcia-Fernandez, M., Domingues, O., Villadiego, J., Martin-Perez, D., Isern, J., Bejarano-Garcia, J. A., Zimmer, J., Perez-Simon, J. A., Toledo-Aral, J. J., Michel, T., Airaksinen, M. S. & Mendez-Ferrer, S., 17 Jan 2019, In : Blood. 133, 3, p. 224-236 13 p.

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Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors

Diniz, C. R. A. F., Biojone, C., Joca, S. R. L., Rantamäki, T., Castren, E., Guimaraes, F. S. & Casarotto, P. C., 21 Feb 2019, In : PeerJ. 7, 21 p., 6493.

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Experiments done in Black-6 mice: what does it mean?

Åhlgren, J. K. & Voikar, V., Apr 2019, In : Lab Animal. 10.1038/s41684-019-0288-8.

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GluA4 Dependent Plasticity Mechanisms Contribute to Developmental Synchronization of the CA3-CA1 Circuitry in the Hippocampus

Atanasova, T., Kharybina, Z., Kaarela, T. A. M., Huupponen, J. T., Luchkina, N., Taira, T. P. & Lauri, S. E., Mar 2019, In : Neurochemical Research. 44, 3, p. 562–571 10 p.

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Housing mice in the individually ventilated or open cages—Does it matter for behavioral phenotype?

Åhlgren, J. & Voikar, V., 7 Mar 2019, In : Genes, Brain and Behavior. 0, 0, p. e12564

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Instability of the mitochondrial alanyl-tRNA synthetase underlies fatal infantile-onset cardiomyopathy

Sommerville, E. W., Zhou, X-L., Olahova, M., Jenkins, J., Euro, L., Konovalova, S., Hilander, T., Pyle, A., He, L., Habeebu, S., Saunders, C., Kelsey, A., Morris, A. A. M., McFarland, R., Suomalainen, A., Gorman, G. S., Wang, E-D., Thiffault, I., Tyynismaa, H. & Taylor, R. W., 15 Jan 2019, In : Human Molecular Genetics. 28, 2, p. 258-268 11 p.

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In vivo Two-Photon Imaging of Anesthesia-Specific Alterations in Microglial Surveillance and Photodamage-Directed Motility in Mouse Cortex

Sun, W., Suzuki, K., Toptunov, D., Stoyanov, S., Yuzaki, M., Khiroug, L. & Dilyatev, A., 7 May 2019, In : Frontiers in Neuroscience. 13, 12 p., 421.

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KCC2-Mediated Cl- Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice

Spoljaric, I., Spoljaric, A., Mavrovic, M., Seja, P., Puskarjov, M. & Kaila, K., 29 Jan 2019, In : Cell Reports. 26, 5, p. 1073-+ 12 p.

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Large-scale brain modes reorganize between infant sleep states and carry prognostic information for preterms

Tokariev, A., Roberts, J. A., Zalesky, A., Zhao, X., Vanhatalo, S., Breakspear, M. & Cocchi, L., 13 Jun 2019, In : Nature Communications. 10, 9 p., 2619.

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More dampened monocytic Toll-like receptor 4 response to lipopolysaccharide and its association with cognitive function in Chinese Han first-episode patients with schizophrenia

Chen, S., Tian, L., Chen, N., Xiu, M-H., Wang, Z-R., Wang, Y-C., Tan, Y-L. & Wang, C-Y., Apr 2019, In : Schizophrenia Research. 206, p. 300-306 7 p.

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NETO1 Regulates Postsynaptic Kainate Receptors in CA3 Interneurons During Circuit Maturation

Orav, E., Dowavic, I., Huupponen, J., Taira, T. & Lauri, S., 2019, In : Molecular Neurobiology.

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Neuronal activation stimulates cytomegalovirus promoter-driven transgene expression

Bäck, S., Dossat, A., Parkkinen, I., Koivula, P., Airavaara, M., Richie, C. T., Chen, Y-H., Wang, Y. & Harvey, B. K., 2019, In : Molecular therapy-Methods & clinical development.

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Neurotrophin receptor Ntrk2b function in the maintenance of dopamine and serotonin neurons in zebrafish

Sahu, M. P., Pazos-Boubeta, Y., Pajanoja, C., Rozov, S., Panula, P. & Castren, E., 14 Feb 2019, In : Scientific Reports. 9, 13 p., 2036.

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Overlapping anatomical networks convey cross-modal suppression in the sighted and co-activation of "visual" and auditory cortex in the blind

Anurova, I., Carlson, L. S. & Rauschecker, J. P., 2019, (Accepted/In press) In : Cerebral Cortex.

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Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke

Kolosowska, N., Keuters, M. H., Wojciechowski, S., Keksa-Goldsteine, V., Laine, M., Malm, T., Goldsteins, G., Koistinaho, J. & Dhungana, H., 1 Aug 2019, In : Neurotherapeutics.

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PPAR beta/delta-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1 Delta E9 astrocytes

Konttinen, H., Gureviciene, I., Oksanen, M., Grubman, A., Loppi, S., Huuskonen, M. T., Korhonen, P., Lampinen, R., Keuters, M., Belaya, I., Tanila, H., Kanninen, K. M., Goldsteins, G., Landreth, G., Koistinaho, J. & Malm, T., Jan 2019, In : Glia. 67, 1, p. 146-159 14 p.

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Preterm Birth Changes Networks of Newborn Cortical Activity

Tokariev, A., Stjerna, S., Lano, A., Metsäranta, M., Palva, J. M. & Vanhatalo, S., Feb 2019, In : Cerebral Cortex. 29, 2, p. 814-826 13 p.

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Quantitative changes in perineuronal nets in development and posttraumatic condition

Lipachev, N., Arnst, N., Melnikova, A., Jäälinoja, H., Kochneva, A., Zhigalov, A., Kulesskaya, N., Aganov, A. V., Mavlikeev, M., Rauvala, H., Kiyasov, A. P. & Paveliev, M., Jun 2019, In : Journal of Molecular Histology. 50, 3, p. 203-216 14 p.

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Regeneration of Dopaminergic Neurons in Adult Zebrafish Depends on Immune System Activation and Differs for Distinct Populations

Caldwell, L. J., Davies, N. O., Cavone, L., Mysiak, K. S., Semenova, S. A., Panula, P., Armstrong, J. D., Becker, C. G. & Becker, T., 12 Jun 2019, In : Journal of Neuroscience. 39, 24, p. 4694-4713 20 p.

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Resting state cross-frequency coupling networks in human electrophysiological recordings

Siebenhuehner, F., Wang, S. H., Arnulfo, G., Palva, S. O. & Palva, J. M., 23 Jan 2019, (Submitted) In : PLoS Biology.

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The primate-specific peptide Y-P30 regulates morphological maturation of neocortical dendritic spines

Neumann, J. R., Dash-Wagh, S., Jack, A., Raek, A., Juengling, K., Hamad, M. I. K., Pape, H-C., Kreutz, M. R., Puskarjov, M. & Wahle, P., 13 Feb 2019, In : PLoS One. 14, 2, 23 p., 0211151.

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Transient modification of lin28b expression - Permanent effects on zebrafish growth

Leinonen, J. T., Chen, Y-C., Tukiainen, T., Panula, P. & Widen, E., 5 Jan 2019, In : Molecular and Cellular Endocrinology. 479, p. 61-70 10 p.

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TrkB-ICD Fragment, Originating From BDNF Receptor Cleavage, Is Translocated to Cell Nucleus and Phosphorylates Nuclear and Axonal Proteins

Fonseca-Gomes, J., Jerónimo-Santos, A., Lesnikova, A., Casarotto, P., Castrén, E., Sebastião, A. M. & Diógenes, M. J., 1 Feb 2019, In : Frontiers in Molecular Neuroscience. 12

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2018

Aberrant Inclusion of a Poison Exon Causes Dravet Syndrome and Related SCN1A-Associated Genetic Epilepsies

EuroEPINOMICS Rare Epilepsy Syndro, Carvill, G. L. & Lehesjoki, A-E., 6 Dec 2018, In : American Journal of Human Genetics. 103, 6, p. 1022-1029 8 p.

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A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions

Nikkanen, J., Landoni, J. C., Balboa, D., Haugas, M., Partanen, J., Paetau, A., Isohanni, P., Brilhante, V. & Suomalainen, A., Jan 2018, In : EMBO molecular medicine. 10, 1, p. 13-21 9 p.

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Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling

Richter, M., Murtaza, N., Scharrenberg, R., White, S. H., Johanns, O., Walker, S., Yuen, R. K. C., Schwanke, B., Bedürftig, B., Henis, M., Scharf, S., Kraus, V., Dörk, R., Hellmann, J., Lindenmaier, Z., Ellegood, J., Hartung, H., Kwan, V., Sedlacik, J., Fiehler, J. & 7 othersSchweizer, M., Lerch, J. P., Hanganu-Opatz, I. L., Morellini, F., Scherer, S. W., Singh, K. K. & Calderon de Anda, F., 2018, In : Molecular Psychiatry.

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Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN

Diniz, C. R. A. F., Casarotto, P. C., Fred, S. M., Biojone, C., Castrén, E. & Joca, S. R. L., Jun 2018, In : Neuropharmacology. 135, p. 163-171 9 p.

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Automated analysis of images for molecular quantification in immunohistochemistry

Guirado, R., Carceller, H., Castillo-Gomez, E., Castren, E. & Nacher, J., Jun 2018, In : Heliyon. 4, 6, 16 p., 00669.

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Behavioural characterization of C57BL/6N and BALB/c female mice in social home cage – Effect of mixed housing in complex environment

Heinla, I., Åhlgren, J., Vasar, E. & Voikar, V., 1 May 2018, In : Physiology & Behavior. 188, p. 32-41 10 p.

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Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti seizure efficacy

Brandt, C., Seja, P., Töllner, K., Römermann, K., Hampel, P., Kalesse, M., Kipper, A., Feit, P. W., Lykke, K., Toft-Bertelsen, T. L., Paavilainen, P., Spoljaric, I., Puskarjov, M., MacAulay, N., Kaila, K. & Löscher, W., Dec 2018, In : Neuropharmacology. 143, p. 186-204 19 p.

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Comparison of methods to identify modules in noisy or incomplete brain networks

Williams, N., Arnulfo, G., Wang, S., Nobili, L., Palva, S. & Palva, M., 2018, (Accepted/In press) In : Brain Connectivity.

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Cu-II(atsm) Attenuates Neuroinflammation

Choo, X. Y., Liddell, J. R., Huuskonen, M. T., Grubman, A., Moujalled, D., Roberts, J., Kysenius, K., Patten, L., Quek, H., Oikari, L. E., Duncan, C., James, S. A., McInnes, L. E., Hayne, D. J., Donnelly, P. S., Pollari, E., Vähätalo, S., Lejavova, K., Kettunen, M., Malm, T. & 3 othersKoistinaho, J., White, A. R. & Kanninen, K. M., 24 Sep 2018, In : Frontiers in Neuroscience. 12, 14 p., 668.

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Culturing primary neurons from rat hippocampus and cortex

Sahu, M. P., Nikkilä, O., Lågas, S. A., Kolehmainen, S. & Castrén, E., 13 Dec 2018, (Submitted) In : BioRxiv beta : the preprint server for biology.

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Defining the phenotypic spectrum of SLC6A1 mutations

Johannesen, K. M., Gardella, E., Linnankivi, T., Courage, C., de Saint Martin, A., Lehesjoki, A-E., Mignot, C., Afenjar, A., Lesca, G., Abi-Warde, M-T., Chelly, J., Piton, A., Merritt, J. L., Rodan, L. H., Tan, W-H., Bird, L. M., Nespeca, M., Gleeson, J. G., Yoo, Y., Choi, M. & 30 othersChae, J-H., Czapansky-Beilman, D., Reichert, S. C., Pendziwiat, M., Verhoeven, J. S., Schelhaas, H. J., Devinsky, O., Christensen, J., Specchio, N., Trivisano, M., Weber, Y. G., Nava, C., Keren, B., Doummar, D., Schaefer, E., Hopkins, S., Dubbs, H., Shaw, J. E., Pisani, L., Myers, C. T., Tang, S., Tang, S., Pal, D. K., Millichap, J. J., Carvill, G. L., Helbig, K. L., Mecarelli, O., Striano, P., Helbig, I. & Rubboli, G., Feb 2018, In : Epilepsia. 59, 2, p. 389-402 14 p.

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De novo variants in neurodevelopmental disorders with epilepsy

EuroEPINOMICS- RES Consortium, Heyne, H. O., Linnankivi, T., Palotie, A., Daly, M. J. & Lehesjoki, A-E., Jul 2018, In : Nature Genetics. 50, 7, p. 1048-1058 11 p.

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Depicting regional microglial activation and its importance for anxiety-related behaviors

Piirainen, S., Bisht, K., Tremblay, M-E. & Tian, L., Sep 2018, In : Neurology, Psychiatry and Brain Research. 29, p. 19 1 p.

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Differential Spinal and Supraspinal Activation of Glia in a Rat Model of Morphine Tolerance

Jokinen, V., Sidorova, Y., Viisanen, H., Suleymanova, I., Tiilikainen, H., Li, Z., Lilius, T. O., Matlik, K., Anttila, J. E., Airavaara, M., Tian, L., Rauhala, P. V. & Kalso, E. A., 1 Apr 2018, In : Neuroscience. 375, p. 10-24 15 p.

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Dynamic large-scale network synchronization from perception to action

Hirvonen, J. S., Monto, S. P., Wang, S. H., Palva, J. M. & Palva, S. O., 2018, In : Network neuroscience. 2, 4, p. 442-463 22 p.

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Effects of the Antidepressant Fluoxetine on the Somatostatin Interneurons in the Basolateral Amygdala

Carceller, H., Perez-Rando, M., Castren, E., Nacher, J. & Guirado, R., 21 Aug 2018, In : Neuroscience. 386, p. 205-213 9 p.

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