Research output per year
Research output per year
Organisation profile
Organisation Profile
Our research is focused on the changes in organ-specific (organotypic) endothelial cells in context of metabolic diseases.
Fields of Science
- 1182 Biochemistry, cell and molecular biology
- Vascular biology
- Blood vessels
- Lymphatic vessels
- Metabolic diseases
- Endothelial cells
- Vascular leakage
International and National Collaboration
Publications and projects within past five years.
Profiles
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Sinem Karaman
- Medicum - Title of Docent
- INDIVIDRUG - Individualized Drug Therapy - Academy Research Fellow
- Organotypic Vasculature Lab
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Biomedicine - Supervisor for doctoral programme
Person: U3 Research and teaching staff
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Madeleine Helena Lackman
- INDIVIDRUG - Individualized Drug Therapy - Doctoral Researcher
- Organotypic Vasculature Lab
- Doctoral Programme in Integrative Life Science
Person: U1 Research and teaching staff, Doctoral Researcher
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Satu Pauliina Paavonsalo
- INDIVIDRUG - Individualized Drug Therapy - Doctoral Researcher
- Organotypic Vasculature Lab
- Doctoral Programme in Biomedicine
Person: U1 Research and teaching staff, Doctoral Researcher
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Emmi Pakarinen
- INDIVIDRUG - Individualized Drug Therapy - Postdoctoral Researcher
- Organotypic Vasculature Lab
Person: U2 Teaching and research staff
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Yelin Subashi, M.Sc.
- INDIVIDRUG - Individualized Drug Therapy - Doctoral Researcher
- Organotypic Vasculature Lab
- Doctoral Programme in Biomedicine
Person: U1 Research and teaching staff, Doctoral Researcher
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Multi-omics characterization of lymphedema-induced adipose tissue resulting from breast cancer-related surgery
Karaman, S., Lehti, S., Zhang, C., Taskinen, M.-R., Käkelä, R., Mardinoglu, A., Brorson, H., Alitalo, K. & Kivelä, R., 31 Oct 2024, In: FASEB Journal. 38, 20, 13 p., e70097.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer’s disease-related amyloid pathology
Antila, S., Chilov, D., Nurmi, H., Li, Z., Näsi, A., Gotkiewicz, M., Sitnikova, V., Jäntti, H., Acosta, N., Koivisto, H., Ray, J., Keuters, M. H., Sultan, I., Scoyni, F., Trevisan, D., Wojciechowski, S., Kaakinen, M., Dvořáková, L., Singh, A. & Jukkola, J. & 7 others, , 2024, In: Nature Cardiovascular Research. 3, p. 474–491 41 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Bexmarilimab-induced macrophage activation leads to treatment benefit in solid tumors: The phase I/II first-in-human MATINS trial
Rannikko, J. H., Verlingue, L., de Miguel, M., Pasanen, A., Robbrecht, D., Skytta, T., Iivanainen, S., Shetty, S., Ma, Y. T., Graham, D. M., Arora, S. P., Jaakkola, P., Yap, C., Xiang, Y., Mandelin, J., Karvonen, M. K., Jalkanen, J., Karaman, S., Koivunen, J. P. & Minchom, A. & 2 others, , 19 Dec 2023, In: Cell Reports Medicine. 4, 12, 17 p., 101307.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
DLL4/Notch3/WNT5B axis mediates bidirectional prometastatic crosstalk between melanoma and lymphatic endothelial cells
Alve, S., Gramolelli, S., Jukonen, J., Juteau, S., Pink, A., Manninen, A. A., Hänninen, S., Monto, E., Lackman, M. H., Carpen, O., Saharinen, P., Karaman, S., Vaahtomeri, K. & Ojala, P. M., 16 Nov 2023, In: JCI INSIGHT. 9, 1, 21 p., e171821.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium
Anisimov, A., Fang, S., Hemanthakumar, K. A., Örd, T., van Avondt, K., Chevre, R., Toropainen, A., Singha, P., Gilani, H., Nguyen, S. D., Karaman, S., Korhonen, E. A., Adams, R. H., Augustin, H. G., Öörni, K., Soehnlein, O., Kaikkonen, M. U. & Alitalo, K., 2023, In: Nature Cardiovascular Research. 2, 3, p. 307-321 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Activities
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Emma Viittala's thesis supervisory board member
Karaman, S. (Supervisor)
2023 → …Activity: Examination types › Member of doctoral thesis committee / follow-up group
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Invited talk at Bioinfocongress III – Vascular endothelial growth factor receptors in organ-specific vessel maintenance
Karaman, S. (Speaker)
15 Oct 2022Activity: Talk or presentation types › Invited talk
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Supervising Erasmus+ intern Gizem Demirci
Karaman, S. (Teacher)
29 Jul 2022 → 21 Oct 2022Activity: Other activity types › Types for other activities - Other
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Invited talks at Metabolism seminar – Organotypic responses of endothelial cells to metabolic challenges
Karaman, S. (Speaker), Subashi, Y. (Speaker) & Lackman, M. H. (Speaker)
20 Dec 2022Activity: Talk or presentation types › Invited talk
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Invited talk at EnVI Lab (INSERMU1096) University of Rouen - Interplay of vascular endothelial growth factor receptors in organ-specific vessel maintenance
Karaman, S. (Speaker)
7 Mar 2022Activity: Talk or presentation types › Invited talk