• Haartmaninkatu 8, Biomedicum, B309b

    00014 Helsinki

    Finland

Organization profile

Organisation Profile

Pregnancy and Genes - translational research in common obstetric disorders

Pre-eclampsia, fetal growth restriction and gestational diabetes mellitus are common disorders of pregnancy. The impact of these disorders is not limited to obstetric and pediatric domains. They are also associated with increased risk of morbidity in later life of both the mother and the child. We investigate susceptibility genes, molecular mechanisms, risk factors, and implications to later life.

Postdoctoral fellows: 

Tiina Jääskeläinen PhD, Jenni Heikkinen-Eloranta MD, Pia Villa MD, PhD,  Inkeri Lokki PhD, Miira Klemetti MD PhD

Graduate students:

Tea Kaartokallio MSc, Katja Murtoniemi MD, Sanna Suomalainen-König MD

Research nurse: Eija Kortelainen

Laboratory technician: Susanna Mehtälä

 

 

 

Fields of Science

  • 311 Basic medicine
  • molecular genetics
  • 312 Clinical medicine
  • pre-eclampsia
  • gestational diabetes

International and National Collaboration Publications and projects within past five years.

Projects

Finngen: FinnGen

Palotie, A., Pitkänen, K., Jalanko, A., Lyhs, U., Donner, K. M., Kaunisto, M., Kurki, M. I., Kristiansson, K., Laiho, P., Laivuori, H., Loukola, A., Palta, P., Perola, M., Kajanne, R., Harju, J. J. & Havulinna, A.

15/08/2017 → …

Project: Research project

HLA-alueen geenien yhteys HELLP-oireyhtymään

Heikkinen-Eloranta, J., Laivuori, H., Lokki, A. I. & Lokki, M.

31/10/2013 → …

Project: Research project

Severe pre-eclampsia

Heikkinen-Eloranta, J., Lokki, A. I. & Laivuori, H.

01/01/201431/01/2015

Project: Research project

Publications

Äidin verestä otettavan sikiötestin (NIPT) vaikutus jatkotutkimuksiin osallistumiseen ja löydöksiin seulontapositiivisissa raskauksissa

Husu, A-K., Laivuori, H., Karhu, R., Saarela, T. & Tihtonen, K., 2020, In : Duodecim. 136, 3, p. 315-322 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Associations of antenatal glucocorticoid exposure with mental health in children

Wolford, E., Lahti-Pulkkinen, M., Girchenko, P., Lipsanen, J., Tuovinen, S., Lahti, J., Heinonen, K., Hämäläinen, E., Kajantie, E., Pesonen, A-K., Villa, P. M., Laivuori, H., Reynolds, R. M. & Räikkönen, K., Jan 2020, In : Psychological Medicine. 50, 2, p. 247-257 11 p., 0033291718004129.

Research output: Contribution to journalArticleScientificpeer-review

Cohort Profile: The Finnish Gestational Diabetes (FinnGeDi) Study

Keikkala, E., Mustaniemi, S., Koivunen, S., Kinnunen, J., Viljakainen, M., Männistö, T., Ijäs, H., Pouta, A., Kaaja, R., Eriksson, J. G., Laivuori, H., Gissler, M., Erkinheimo, T-L., Keravuo, R., Huttunen, M., Metsälä, J., Stach‑Lempinen, B., Klemetti, M. M., Tikkanen, M., Kajantie, E. & 1 others, Vääräsmäki, M., 1 Jun 2020, In : International Journal of Epidemiology. 49, 3, p. 762-763 2 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia

Wedenoja, S., Yoshihara, M., Teder, H., Sariola, H., Gissler, M., Katayama, S., Wedenoja, J., Häkkinen, I. M. K., Ezer, S., Linder, N., Lundin, J., Skoog, T., Sahlin, E., Iwarsson, E., Pettersson, K., Kajantie, E., Mokkonen, M., Heinonen, S., Laivuori, H., Krjutskov, K. & 1 others, Kere, J., Sep 2020, In : EBioMedicine. 59, 13 p., 102872.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Imprinting disorders in children born after ART: a Nordic study from the CoNARTaS group

Henningsen, A. A., Gissler, M., Rasmussen, S., Opdahl, S., Wennerholm, U. B., Spangsmose, A. L., Tiitinen, A., Bergh, C., Romundstad, L. B., Laivuori, H., Forman, J. L., Pinborg, A. & Lidegaard, O., May 2020, In : Human Reproduction. 35, 5, p. 1178-1184 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Activities

European Congress of the International Society for the Study of Hypertension in Pregnancy

Tea Kaartokallio (Speaker)

2 Oct 20194 Oct 2019

Activity: Talk or presentation typesOral presentation

AHA Scientific Sessions 2019

Tiina Jääskeläinen (Attendee)

16 Nov 201918 Nov 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

26th European Congress on Obesity

Tiina Jääskeläinen (Attendee)

28 Apr 20191 May 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Perinatologisen seuran syyskoulutuspäivät

Tiina Jääskeläinen (Speaker)

3 Oct 2019

Activity: Talk or presentation typesInvited talk

Lunenfeld-Tanenbaum Research Institute (LTRI) Seminar Series

Miira (Klemetti) Pettersson (Speaker: Presenter)

16 May 2018

Activity: Participating in or organising an event typesPublic Talks

Prizes

Best doctoral thesis

Jääskeläinen, Tiina (Recipient), 2010

Prize: Prizes and awards

The Rike Fellowship Award

Laivuori, Hannele (Recipient), 2002

Prize: Prizes and awards

Young Investigator Award

Jääskeläinen, Tiina (Recipient), 2009

Prize: Prizes and awards

Press / Media

Minä väitän /Helsingin Sanomat 15.10.2019

Tiina Jääskeläinen

15/10/2019

1 Media contribution

Press/Media: Press / Media

Ylen Aamu

Tiina Jääskeläinen

30/01/2019

1 Media contribution

Press/Media: Press / Media

Tiedekulma: Syöt mitä olet

Tiina Jääskeläinen

30/01/2019

1 Media contribution

Press/Media: Press / Media

SISU – MED­ICAL BREAK­THROUGHS FROM OPEN SCI­ENCE

Hannele Laivuori

28/10/2016

1 Media contribution

Press/Media: Press / Media