Projects per year
Organisation profile
Organisation Profile
Pregnancy and Genes - translational research in common obstetric disorders
Pre-eclampsia, fetal growth restriction and gestational diabetes mellitus are common disorders of pregnancy. The impact of these disorders is not limited to obstetric and pediatric domains. They are also associated with increased risk of morbidity in later life of both the mother and the child. We investigate susceptibility genes, molecular mechanisms, risk factors, and implications to later life.
Postdoctoral fellows:
Tiina Jääskeläinen PhD, Jenni Heikkinen-Eloranta MD, Pia Villa MD, PhD, Inkeri Lokki PhD, Miira Klemetti MD PhD
Graduate students:
Tea Kaartokallio MSc, Katja Murtoniemi MD, Sanna Suomalainen-König MD
Research nurse: Eija Kortelainen
Laboratory technician: Susanna Mehtälä
Fields of Science
- 311 Basic medicine
- molecular genetics
- 312 Clinical medicine
- pre-eclampsia
- gestational diabetes
International and National Collaboration
Publications and projects within past five years.
Profiles
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Tiina Jääskeläinen
- Department of Food and Nutrition - University Lecturer
- Medicum - Visiting scholar
- Pregnancy and Genes
- Doctoral Programme in Population Health - Supervisor for doctoral programme
Person: Visiting scholar, U3 Research and teaching staff
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Eija Kortelainen
- Department of Medical and Clinical Genetics - Clinical Research Nurse
- Pregnancy and Genes
Person: M5 Teaching and research support staff
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Pre-eclampsia and future cardiovascular health: An underused opportunity to improve family health
Jääskeläinen, T. (Project manager)
01/01/2019 → …
Project: Research project
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Finngen: FinnGen
Palotie, A. (Project manager), Pitkänen, K. (Principal Investigator), Jalanko, A. (Principal Investigator), Lyhs, U. (Participant), Donner, K. M. (Participant), Kaunisto, M. (Participant), Kurki, M. I. (Participant), Kristiansson, K. (Participant), Laiho, P. (Participant), Laivuori, H. (Participant), Loukola, A. (Participant), Palta, P. (Participant), Perola, M. (Project manager), Kajanne, R. (Project manager), Harju, J. J. (Project manager) & Havulinna, A. (Project manager)
15/08/2017 → …
Project: Research project
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HLA-alueen geenien yhteys HELLP-oireyhtymään
Heikkinen-Eloranta, J. (Principal Investigator), Laivuori, H. (Participant), Lokki, A. I. (Participant) & Lokki, M.-L. (Participant)
31/10/2013 → …
Project: Research project
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Severe pre-eclampsia
Heikkinen-Eloranta, J. (Participant), Lokki, A. I. (Participant) & Laivuori, H. (Participant)
01/01/2014 → 31/01/2015
Project: Research project
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Alkuraskauden »metabolinen sormenjälki» eroaa raskausdiabeteksen alatyypeissä
Translated title of the contribution :Analysis of early-pregnancy metabolome in early- and late-onset gestational diabetes reveals distinct associations with maternal overweight Research output: Contribution to journal › Comment/debate › Professional
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Analysis of early-pregnancy metabolome in early- and late-onset gestational diabetes reveals distinct associations with maternal overweight
Masalin, S., Klåvus, A., Rönö, K., Koistinen, H. A., Koistinen, V., Kärkkäinen, O., Jääskeläinen, T. J. & Klemetti, M. M., 2024, In: Diabetologia. 16 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Cardiac Structure and Function in 8- to 12-Year-Old Children Following In-Utero Exposure to Preeclampsia (FINNCARE Study)
Renlund-Vikström, M. A., Jääskeläinen, T. J., Kivelä, A., Heinonen, S., Laivuori, H. & Sarkola, T., 6 Aug 2024, In: Journal of the American Heart Association. 13, 15, 14 p., e034494.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Delayed versus early delivery leads to similar outcome in selected cases of preeclampsia in the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC) cohort
FINNPEC Core Investigator Group, Kivisilta, K., Toivonen, E., Kiverä, A., Kortelainen, E., Uotila, J. & Laivuori, H., Jun 2024, In: Pregnancy Hypertension. 36, 5 p., 101129.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Preeclampsia-exposed children’s heart rate variability 8–12 yr after index pregnancy: FINNCARE study
Renlund, M., Tulppo, M. P., Kivelä, A., Laivuori, H., Heinonen, S., Jääskeläinen, T. & Sarkola, T., 3 Jan 2024, In: American Journal of Physiology: Heart and Circulatory Physiology. 326, 1, p. H74-H81 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
Activities
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Lääkäripäivät 2023
Jääskeläinen, T. (Speaker)
26 Jan 2023Activity: Talk or presentation types › Oral presentation
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American Journal of Clinical Nutrition (Journal)
Jääskeläinen, T. (Reviewer)
Oct 2022Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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Nordic obesity meeting
Jääskeläinen, T. (Attendee)
17 Nov 2022 → 19 Nov 2022Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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The Annual Nordic Pharmacoepidemiological Network (NorPEN) meeting
Jääskeläinen, T. (Speaker)
17 Nov 2022Activity: Talk or presentation types › Invited talk
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Perinatologisen seuran syyskoulutuspäivät
Jääskeläinen, T. (Speaker)
29 Sept 2022Activity: Talk or presentation types › Invited talk
Prizes
Press/Media
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Preeclampsia risk linked to blood pressure, BMI
26/11/2020
1 item of Media coverage
Press/Media: Press / Media
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Preeclampsia risk linked to blood pressure, body mass index
26/11/2020
1 item of Media coverage
Press/Media: Press / Media
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-UNIVERSITY OF HELSINKI: Genetic study shows that the risk of preeclampsia is related to blood pressure and body mass index
26/11/2020
1 item of Media coverage
Press/Media: Press / Media
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University of Helsinki: Genetic Study Shows That the Risk of Preeclampsia is Related to Blood Pressure and Body Mass Index
25/11/2020
1 item of Media coverage
Press/Media: Press / Media
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Genetic study shows that the risk of pre-eclampsia is related to blood pressure and body mass index
25/11/2020
2 items of Media coverage
Press/Media: Press / Media